@TOME V2.2
(Nov 2016)
Ref.
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : S23A3_HUMAN: (2015-12-09 )
MSRSPLNPSQLRSVGSQDALAPLPPPAPQNPSTHSWDPLCGSLPWGLSCLLALQHVLVMASLLCVSHLLLLCSLSPGGLSYSPSQLLASSFFSCGMSTILQTWMGSRLPLVQAPSLEFLIPALVLTSQKLPRAIQTPGNSSLMLHLCRGPSCHGLGHWNTSLQEVSGAVVVSGLLQGMMGLLGSPGHVFPHCGPLVLAPSLVVAGLSAHREVAQFCFTHWGLALLVILLMVVCSQHLGSCQFHVCPWRRASTSSTHTPLPVFRLLSVLIPVACVWIVSAFVGFSVIPQELSAPTKAPWIWLPHPGEWNWPLLTPRALAAGISMALAASTSSLGCYALCGRLLHLPPPPPHACSRGLSLEGLGSVLAGLLGSPMGTASSFPNVGKVGLIQAGSQQVAHLVGLLCVGLGLSPRLAQLLTTIPLPVVGGVLGVTQAVVLSAGFSSFYLADIDSGRNIFIVGFSIFMALLLPRWFREAPVLFSTGWSPLDVLLHSLLTQPIFLAGLSGFLLENTIPGTQLERGLGQGLPSPFTAQEARMPQKPREKAAQVYRLPFPIQNLCPCIPQPLHCLCPLPEDPGDEEGGSSEPEEMADLLPGSGEPCPESSREGFRSQK
Atome Classification :
(20 SA)
------------.........10........20........30........40........50........60........70.-.......80........90........100..-.....110.......120.......130...--....140.......150.......160.......170.....-----------..180.---.---.....190.......200...-----....210---------------------------....-----------....220.....------..230.......240..--.....250.......260.....-..270......------.280...--....290.......300.....-----..310..-.----....320.......330.......340.---......350.......360.......-370....---...380....----...--390........400.......410-.........420.......430.....-------..440-....--.....450..-------.....460.......470--..---------.....480.......490.....--..500.......510.....-..520.......530.......540.......550.......560----.........570...------....580.......590.......600.......610-----------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
------------MSRSPL
N
P
S
Q
L
R
SVGSQDALAPLPPPAPQNPSTHSWDPLCGSL
P
W
G
L
S
C
L
L
A
L
Q
H
V
L
V
M
A
S
L
L
C
V
S
H
L
L
L
L
C-SLSPGGLSY
S
P
S
Q
L
L
A
S
S
F
F
S
C
G
M
S
T
I
L
Q
T
W
M-GSRLPLVQAP
S
L
E
F
L
I
P
A
L
V
L
T
S
Q
KL
P
R
A
IQ--TPGNS
S
L
M
L
H
LCRGPSCHGLGHWN
T
S
L
Q
E
VS
G
A
V
V
V
S
G
L
L
Q
G
-----------
M
M
G
LLG---S---PGHVFPHC
G
P
L
V
L
A
P
S
L
V
V
A
G
-----
L
S
A
H
R
E
----------------------------
V
A
Q
F
-----------
C
F
T
H
W
G
L
A
L
L
V
I
------
L
L
M
V
V
C
S
Q
H
LGS
C
Q
F
H
V--CPWRRASTSSTHTP
L
P
V
F
R
L
L
S
V
-
L
I
P
V
A
C
V
W
I
V
S
------
A
F
V
G
F
S
V--
I
P
Q
E
LSAPTKA
P
W
I
WLPHPGEW-----NWPLL
T
P
-
R
----
A
L
A
A
G
I
S
M
A
L
AASTSSL
G
C
Y
A
L
C
G
R
L
LH---LPPPP
P
H
A
C
SRGL
S
L
E
G
L
G
S
V
L
A
G
L
L-GSPMGTA---SSFPNVGKV
G
----
L
IQ--A-
G
S
Q
Q
V
A
H
L
V
G
L
L
C
V
GLGL
S
P
---
R
L
A
Q
L
L
T
TI
P
L
P
V
V
G
G
V
L
G
V
T
Q
A
V
V
L
S-------AGF---S
S
F
Y
--
L
A
DIDSG
R
N
I
-------
F
I
V
G
F
S
I
F
M
A
L
L
L
P
R
W
F
R
--EA---------
P
V
L
FSTGW
S
P
L
D
V
L
L
H
S
L
LTQ
P
I
--
F
L
A
G
L
S
G
F
L
L
ENTI
P
G
T
Q
L
E
-
R
G
L
GQGLPSPF
T
A
Q
E
ARMPQK
P
R
E
K
A
A
Q
VYRLPF
P
I
Q
N
LCPCI------PQP
L
H
CLCPLPEDPG------DEEGGSS
E
P
E
E
M
A
D
LLPGSGEPCPE
S
S
R
EGFRSQK-------------------------------------------------
14
Fugue
81.47
18%
-86
- C8 -
3QE7
2
URAA_ECOLI
A:
[4-410]
----------------------------------------
R
A
I
G
V
S
E
R
P
P
L
L
Q
T
I
P
L
S
L
Q
H
L
F
A
M
F
G
A
T
V
L
V
P
V
L
----------------
F
H
I
N
P
A
T
V
L
L
F
N
G
I
G
T
L
L
Y
L
F
I
---
C
-
K
G
K
I
P
A
Y
L
G
S
S
F
A
F
I
S
P
V
L
L
L
L
P
L
----------------------------------
G
Y
E
V
A
L
G
G
F
I
M
C
G
V
L
F
C
-----------
L
V
S
F
I
V
---
K
K
A
G
T
G
W
L
D
V
L
F
P
P
A
A
M
G
A
I
V
A
V
I
G
-----
L
E
L
A
G
V
----------------------------
A
A
G
M
-----------
A
G
L
L
--------------------
P
A
E
G
Q
T
P
D
S
K
T
--
I
I
I
S
I
T
T
L
A
V
T
V
L
G
S
V
L
F
R
G
F
L
A
-
I
I
P
I
L
I
G
V
L
V
G
------
Y
A
L
S
F
A
M
--
G
I
V
D
T
T
P
I
I
N
A
H
W
F
A
L
P
---
T
L
-----
Y
T
P
R
F
E
W
-
F
----
A
I
L
T
I
L
P
A
A
L
V
V
I
A
E
H
V
G
H
L
V
V
T
A
N
I
V
K
---
K
D
L
L
R
D
P
G
L
H
R
S
M
F
A
N
G
L
S
T
V
I
S
G
F
F
-
G
S
T
P
-
N
T
---
T
Y
G
E
N
I
G
V
M
A
----
I
T
R
--
V
-
Y
S
T
W
V
I
G
G
A
A
I
F
A
I
L
L
S
C
V
G
---
K
L
A
A
A
I
Q
M
I
P
L
P
V
M
G
G
V
S
L
L
L
Y
G
V
I
G
A
-------
S
G
I
---
R
V
L
I
--
E
S
K
V
D
Y
N
K
-----------------------------------------------------
A
Q
N
L
I
L
T
S
V
I
--
L
I
I
G
V
S
G
---------
A
K
V
N
-
I
G
A
A
E
L
K
G
M
A
L
A
T
I
V
G
I
G
L
S
L
I
F
K
L
I
S
-------------------------------------------------------------------------------------------------------------------------------
19
Fugue
77.26
19%
-79
- C8 -
5DA0
2
?
A:
[14-484]
-------------------
Q
R
E
W
F
A
N
P
R
K
D
V
L
A
G
I
V
V
A
L
A
L
I
P
E
A
I
A
F
S
I
I
A
G
----------
V
D
P
Q
V
G
L
Y
A
S
F
I
I
A
L
I
T
A
F
L
G
-
G
R
-
P
G
M
I
S
A
------
A
T
G
A
M
A
L
L
M
T
G
L
V
K
------------------------------------------------------------
D
H
G
I
Q
Y
L
F
A
A
T
V
L
T
G
V
L
Q
V
-----------
V
F
G
W
----------------------------
A
K
-----
L
A
R
Y
L
K
F---------------------------
V
P
R
S
-----------
V
M
V
G
F
V
N
A
L
A
I
L
------
I
F
M
A
Q
L
P
Q
F
V
G
A
N
W
Q
M
Y
--
A
M
V
A
A
G
L
A
I
I
Y
L
L
P
L
V
F
K
A
M
P
S
A
-
L
V
A
I
V
V
L
T
V
V
A
------
V
V
T
G
A
D
V
KT
V
G
D
M
G
T
L
P
T
A
L
P
H
F
Q
F
P
Q
V
P
-----------
L
T
F
-
E
----
T
L
A
I
I
F
P
V
A
L
T
L
S
L
V
G
L
L
E
S
L
L
T
A
Q
L
I
D
---
E
R
T
D
T
T
S
D
K
N
V
E
S
R
G
Q
G
V
A
N
I
V
T
G
F
F
-
G
G
M
A
G
C
A
M
I
G
Q
S
M
I
N
V
T
S
G
G
----
R
G
R
--
L
-
S
T
F
V
A
G
A
F
L
M
V
L
I
L
A
L
---------
Q
P
L
L
V
Q
I
P
M
A
A
L
V
A
V
M
M
V
V
A
I
S
T
F
D
WGSLRFP
K
G
E
---
T
V
V
M
--
L
A
T
V
A
V
T
V
F
T
-------
H
D
L
S
L
G
V
L
I
G
V
V
L
S
A
L
F
F
--
A
R
---------
K
V
S
Q
L
S
Q
V
T
P
V
D
E
V
-
D
G
T
R
T
Y
R
V
R
G
Q
L
F
F
V
S
T
H
D
F
L
H
Q
F
D
F
T
H
P
A
-
R
------
R
V
V
I
D
L
S
D
A
H
F
W
D
G
S
A
V
G
A
L
D
K
V
M
L
K
F
M
R
Q
------------------------------------
G
T
S
V
E
L
R
G
L
--------
N
A
A
S
A
T
L
V
E
R
L
-----------------------------------------------------
4
HHSearch
75.67
19%
-116
- C8 -
3QE7
2
URAA_ECOLI
A:
[4-410]
----------------------------------------------
R
A
I
G
V
S
E
R
P
P
L
L
Q
T
I
P
L
S
L
Q
H
L
F
A
M
F
G
A
T
V
L
V
P
V
L
F
H
-------
I
N
-------
P
A
T
V
L
L
F
N
G
I
G
T
L
L
Y
L
F
I
C
K
G
K
I
P
A
Y
L
G
S
S
F
A
F
I
S
P
V
L
L
L
L
P
----------------------------------
L
G
Y
E
V
A
L
G
G
F
I
M
C
G
V
L
F
C
-----------
L
V
S
F
I
V
K
K
A
G
---
T
G
W
L
D
V
L
F
P
P
A
A
M
G
A
I
V
A
V
I
G
-----
L
E
L
A
G
V
----------------------------
A
A
G
M
A
GLLPAEGQTP
D
S
K
T
I
I
I
S
I
T
T
L
------
A
V
T
V
L
G
S
V
L
F
R
G
-----------------------
F
L
A
I
I
P
I
-
L
I
G
V
L
V
G
Y
A
L
S
------
F
A
M
G
I
V
------
D
T
T
P
I
I
N
A
H
W
F
A
L
P
T
L
Y
--------
T
P
R
F
E
W
-
F
----
A
I
L
T
I
L
P
A
A
L
V
V
I
A
E
H
V
G
H
L
V
V
T
A
N
I
V
K
---
K
D
L
L
R
D
P
G
L
H
R
S
M
F
A
N
G
L
S
T
V
I
S
G
F
F
-
G
S
T
P
N
T
T
----
Y
G
E
N
I
G
V
M
A
----
I
T
R
--
V
-
Y
S
T
W
V
I
G
G
A
A
I
F
A
I
L
L
S
C
V
G
---
K
L
A
A
A
I
Q
M
I
P
L
P
V
M
G
G
V
S
L
L
L
Y
G
V
I
G
A
-------
S
G
I
---
R
V
L
I
E
S
K
V
D
Y
N
K
A
Q
N
L
-------
I
L
T
S
V
I
L
I
I
G
V
S
G
A
K
V
N
I
----------------------------
G
A
A
E
L
K
G
M
--
A
L
A
T
I
V
G
I
G
L
S
L
I
F
K
L
I
S
-------------------------------------------------------------------------------------------------------------------------------------------------------------
21
Fugue
65.77
13%
-73
- C5 -
4A01
9
AVP_VIGRR
A:
[2-766]
GAAILP
D
L
G
T
E
I
L
I
P
V
C
A
V
I
G
I
A
F
A
L
F
Q
W
L
L
V
S
K
V
K
L
S
A
V
D
H
N
V
V
V
K
C
A
E
I
Q
N
A
I
S
E
G
A
T
S
F
L
F
T
E
Y
K
Y
V
G
I
F
M
V
A
F
A
I
L
I
F
L
F
-
L
G
S
V
E
G
F
S
T
S
P
Q
A
C
S
Y
D
K
T
K
T
C
K
P
A
L
A
T
A
I
F
S
-
T
V
S
F
L
L
G
G
V
T
S
L
V
S
G
F
L
G
M
K
I
A
T
Y
A
N
A
R
T
T
L
E
A
R
K
G
V
G
K
A
F
I
T
A
F
R
S
G
A
V
M
G
F
L
L
A
A
N
G
L
L
V
L
Y
I
A
I
N
L
F
K
I
Y
Y
G
DD
W
G
G
L
F
E
A
I
T
G
Y
G
L
G
G
---
S
---
S
M
A
L
F
G
R
V
G
G
G
I
Y
T
K
A
A
D
V
G
A
-----
D
L
V
G
K
V
ERNIPEDDPRNPA
V
I
A
D
N
V
G
D
N
V
GDI
A
G
M
G
S
D
-----------
L
F
G
S
Y
A
E
S
S
C
A
A
------
L
V
V
A
S
I
S
S
F
G
L
N
H
E
L
T
A
M
L
Y
P
L
I
V
S
S
V
G
I
L
V
C
L
L
T
T
L
F
A
T
D
F
-
F
E
I
K
A
V
K
E
I
E
P
------
A
L
K
K
Q
L
V
--
I
S
T
V
L
M
T
I
G
V
A
V
V
S
F
V
A
L
P
T
S
F
-----
T
I
F
N
F
G
V
-
Q
----
K
D
V
K
S
W
Q
L
F
L
C
V
A
V
G
L
W
A
G
L
I
I
G
F
V
T
E
Y
---
Y
T
S
N
A
Y
S
P
V
Q
D
V
A
D
S
C
R
T
G
A
A
T
N
V
I
F
-
G
L
A
L
G
Y
K
---
S
V
I
I
P
I
F
A
I
A
----
I
S
I
--
F
-
V
S
F
T
F
A
A
M
Y
G
I
A
V
A
A
L
G
M
------
L
S
T
I
A
T
G
L
A
I
D
A
Y
G
P
I
S
D
N
A
G
G
I
A
E
M
-------
A
G
M
S
H
R
I
R
E
R
--
T
D
A
L
D
A
A
G
N
T
T
A
A
I
G
K
G
F
A
I
G
S
A
A
L
V
S
L
A
L
F
G
A
F
V
--
S
R
A
SITTVDVL
T
P
K
V
F
I
G
L
I
V
G
A
M
L
P
Y
W
F
S
A
M
T
M
--
K
S
V
G
S
A
A
L
K
M
V
E
E
V
R
R
Q
F
N
T
I
P
G
L
M
E
G
T
A
K
P
---
D
Y
A
T
C
V
K
I
S
T
D
A
S
I
K
E
M
I
P
P
G
A
L
V
M
L
T
P
L
V
V
G
I
L
FG
V
E
T
L
S
G
V
L
A
G
S
L
V
S
G
V
Q
I
A
I
S
A
S
N
T
G
G
A
W
D
N
A
K
K
Y
I
E
A
G
A
S
E
H
A
R
S
L
G
P
K
G
S
D
C
H
K
A
A
V
I
G
D
T
I
G
DPLKDT
S
G
P
S
L
N
I
L
I
K
L
M
A
V
E
S
L
V
F
A
P
F
F
A
T
HGG
L
L
F
K
I
F
17
Fugue
62.75
18%
-119
- C8 -
4TXD
-
?
A:
[21-369]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
R
D
V
L
A
E
L
G
L
G
D
L
R
P
Y
L
R
S
I
G
DKDRI
F
P
K
A
H
R
----------------------------
I
E
V
V
-----------
F
L
V
R
A
A
N
Y
L
L
L
R
T
E
G
AGT
I
N
M
T
T
L
E
Y
S
G
G
A
M
E
V
P
V
--
I
Q
P
Q
K
L
M
A
V
T
R
R
Q
M
L
Q
L
L
R
E
Y
R
D
S
L
D
E
V
S
K
R
W
L
V
Q
EV
I
G
K
A
K
D
L
G
F
K
K
--
V
S
E
E
W
N
C
T
I
Q
G
M
D
G
F
C
P
H
C
T
I
F
-----
G
A
A
L
T
E
Q
H
N
----
E
K
F
G
G
L
S
I
G
I
K
T
R
V
R
F
D
P
A
F
A
T
Q
R
R
I
------
T
P
E
T
H
N
K
V
T
E
G
-
H
L
S
M
T
G
Q
A
L
F
S
E
V
-
H
V
E
P
G
T
-------
V
F
I
G
R
A
E
----
L
V
D
--
L
-
T
E
P
E
L
V
A
T
L
Y
S
L
A
T
L
R
E
L
G
G
---
R
-----
S
G
I
Y
G
T
V
R
V
E
I
L
G
V
K
A
G
K
--
Y
-------
A
S
T
---
T
A
Y
D
--
L
A
A
E
N
A
G
K
G
Y
-------
E
E
V
K
K
N
L
K
E
R
L
E
K
L
G
F
T
P
V
D
N
S
---------
K
L
L
A
A
V
D
H
K
D
P
N
G
L
F
K
D
L
W
R
S
S
I
--
D
F
A
E
K
M
V
K
W
V
E
E
L
K
G
G
G
--------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
56.29
30%
209
- C8 -
4ABX
-
RECN_DEIRA
A:
[-1-236]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
Q
R
E
R
A
R
Q
I
D
L
L
A
F
Q
V
Q
E
I
S
E
V
S
------
P
-----------
D
P
G
------
E
E
E
G
L
N
T
E
L
S
R
L
S
N
L
H
T
I
A
Q
A
A
A
G
G
V
E
L
L
S
D
G
D
L
N
-------------------------------------------------
1
PsiBlast_PDB
53.52
23%
-75
- C8 -
3QE7
2
URAA_ECOLI
A:
[176-362]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
R
G
F
L
A
-
I
I
P
I
L
I
G
V
L
V
G
------
Y
A
L
S
F
A
M
--
G
I
V
D
T
T
P
I
I
N
A
H
W
F
A
L
P
------------
T
L
Y
T
P
-
R
F
E
W
F
A
I
L
T
I
L
P
A
A
L
V
V
I
A
E
H
V
G
H
L
V
V
T
A
N
I
V
K
KDL
L
R
D
P
G
L
H
---
R
S
M
F
A
N
G
L
S
T
V
I
S
G
F
F
-
G
S
T
P
N
T
T
---
Y
G
-
E
N
I
G
V
M
A
----
I
T
R
--
V
-
Y
S
T
W
V
I
G
G
A
A
I
F
A
I
L
L
S
C
V
G
---
K
L
A
A
A
I
Q
M
I
P
L
P
V
M
G
G
V
S
L
L
L
Y
G
V
I
G
A
-------
S
G
I
---
R
V
L
I
--
E
S
K
V
D
Y
N
K
A
Q
-------
N
L
I
L
T
S
V
I
L
I
I
G
V
S
G
A
K
V
--
N
I
---------
G
A
A
E
L
K
G
M
A
L
A
T
I
V
G
I
G
L
S
L
I
F
K
--
L
I
S
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
Fugue
50.45
13%
-96
- C6 -
1B9I
1
RIFK_AMYMS
A:
[5-388]
--------------
K
A
P
-
E
F
P
A
W
P
Q
Y
-
D
D
A
E
R
N
G
L
V
R
A
L
E
Q
G
Q
W
W
R
M
G
G
D
E
V
N
S
F
E
R
E
F
A
A
H
H
G
A
A
H
A
L
A
V
T
N
G
T
H
A
L
E
L
A
L
Q
V
M
G
V
G
P
G
T
E
V
I
V
P
A
F
----
T
F
I
--
S
S
S
Q
A
A
Q
R
-
L
-
G
A
V
T
V
P
V
D
V
D
A
A
T
Y
N
L
D
P
E
A
V
A
A
A
V
T
P
--------
R
T
K
V
I
M
P
V
--------------
H
----
M
A
G
L
M
A
D
M
D
A
L
A
K
-----------
I
S
A
D
T
---------
G
-------------------------------------------------------------------------------------------
V
P
L
L
Q
D
A
A
H
A
H
G
A
R
W
Q
-----
G
K
R
V
G
E
L
---
D
S
I
A
T
F
S
F
Q
N
-------------------------------------------------------------
G
-
K
----
L
M
T
A
G
E
G
G
A
V
V
F
P
D
G
E
T
E
K
Y
E
T
A
F
L
R
H
S
---
C
G
R
P
R
D
D
R
---------------
R
Y
F
-
H
K
I
A
G
S
N
---
M
R
L
N
----
E
F
----
S
A
S
--
V
-
L
R
A
Q
L
A
R
L
D
E
Q
I
A
V
R
D
E
R
W
T
---
L
L
S
R
L
L
G
A
I
D
-----
G
V
V
P
Q
G
G
D
V
R
A
D
-------
R
N
S
---
H
Y
M
A
--
M
F
R
I
P
---------------
G
L
T
E
E
R
R
N
A
L
V
D
R
L
V
--
E
A
---------
G
L
P
A
F
A
A
F
R
A
I
Y
R
-------
T
D
A
--
F
W
E
----------------------
L
G
A
P
D
E
S
V
D
A
I
A
R
R
C
P
N
T
D
A
I
S
S
D
C
V
W
L
H
H
R
V
L
L
--------------------------------------
A
G
E
P
E
L
H
A
T
A
E
I
I
A
D
A
V
G
R
A
----------------------------------------------------------
8
HHSearch
27.34
21%
851
- C7 -
3MHP
-
C:
[10-23]
-------------------------
T
A
Y
D
D
L
K
P
P
S
S
P
S
P
T
K
P
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
Fugue
27.33
27%
383
- C8 -
1LBJ
-
A:
[1-22]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
V
P
I
F
T
Y
G
E
L
Q
R
M
Q
E
K
E
R
N
K
G
Q
-------------------------------------------------------------------------------------------------------------------------------
11
HHSearch
27.33
24%
74
- C8 -
1WPW
-
LEU3_SULTO
A:
[205-246]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
L
V
R
---
N
P
Q
M
F
D
V
I
V
T
E
N
V
Y
G
D
I
L
S
D
E
A
S
Q
I
A
-
G
S
L
-
G
I
A
---
P
S
-
A
N
I
G
D
K
K
----
A
L
F
--
E
-
P
V
H
G
A
A
F
D
I
A
G
K
N
I
G
N
P
T
A
F
---
L
L
S
V
S
M
M
Y
E
R
M
Y
E
L
S
N
D
D
R
Y
I
K
A
S
R
A
L
-------
E
N
A
---
I
Y
L
V
--
Y
K
E
R
K
A
L
T
P
D
-------
V
G
G
N
A
T
T
D
D
L
I
N
E
I
Y
N
K
L
--
G
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
Fugue
27.00
27%
416
* C8 *
2VOG
-
B:
[4-25]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
A
E
V
Q
I
A
R
K
L
Q
C
I
A
D
Q
F
H
R
L
H
T
------------------------------------------------------------------------------------------------------------------------
5
HHSearch
26.11
12%
-38
- C8 -
3QE7
2
URAA_ECOLI
A:
[45-145]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
V
L
L
F
N
G
I
G
T
L
L
Y
L
F
I
C
K
G
K
I
P
A
Y
---
L
G
-
S
S
F
A
F
I
S
P
V
L
L
L
L
P
LG
Y
E
V
A
L
G
G
F
I
M
C
G
V
L
F
C
L
V
S
F
I
V
K
K
A
G
T
G
W
L
D
V
L
F
P
P
A
A
M
G
A
I
V
A
V
I
G
L
E
L
A
G
-------
V
A
A
---
G
M
A
G
--
L
L
P
A
E
G
Q
T
P
D
-------
S
K
T
I
I
I
S
I
T
T
L
A
V
T
V
L
G
S
--
V
L
---------
F
R
G
F
L
A
I
I
P
I
L
I
G
V
L
V
G
Y
A
L
S
F
A
--
M
G
I
V
D
T
T
P
I
I
N
A
H
W
F
A
L
P
T
L
-
Y
T
P
R
F
E
W
F
A
I
L
T
I
L
P
A
A
L
V
V
I
A
E
H
V
G
H
L
V
V
T
A
N
I
V
K
K
D
L
L
R
D
P
------
G
L
H
R
S
M
F
A
N
G
L
S
T
V
I
------
S
G
F
F
G
S
T
P
N
T
T
Y
G
E
N
I
G
V
M
A
I
T
R
V
Y
S
T
W
V
I
G
G
A
A
I
-------------------------------------------------
18
Fugue
24.71
16%
377
- C8 -
3RA3
-
?
B:
[3-27]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
R
L
K
Q
K
N
A
R
L
K
Q
E
I
A
A
L
E
Y
E
I
A
A
L
E
-------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
24.51
38%
48
* C7 *
1L5A
-
?
A:
[248-294]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
A
E
P
D
A
P
W
L
W
L
P
F
M
N
R
W
GSVAA
N
V
P
G
L
M
V
-
N
----
S
L
P
L
---
L
R
L
S
A
Q
Q
T
S
L
G
N
Y
L
K
Q
S
G
Q
A
I
---
R
S
L
Y
L
H
G
R
Y
R
I
E
Q
I
E
Q
D
Q
G
L
N
A
E
Q
S
Y
-
F
M
S
P
F
I
N
---
I
L
P
F
E
S
P
H
F
A
----
D
C
Q
--
T
-
E
L
K
V
L
A
S
G
S
A
E
G
I
N
F
T
F
R
G
S
---
P
Q
H
E
L
C
L
D
I
T
A
D
L
A
S
Y
P
Q
S
H
W
Q
S
H
C
E
R
-------
F
P
R
---
F
F
E
Q
--
L
L
A
R
F
Q
Q
V
E
Q
-------
D
V
A
R
L
L
A
E
P
A
A
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
HHSearch
24.31
40%
1408
- C1 -
1F3K
-
A:
[3-12]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
A
D
E
P
C
D
V
F
S
L
D
C
C
T
G
I
C
-------------------------------------------------
23
Fugue
24.22
19%
340
- C8 -
1I5K
-
D:
[402-427]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
K
L
T
A
D
A
E
L
Q
R
L
K
N
E
R
H
E
E
A
E
L
E
R
L
K
-------------------------------------------------------------------------------------------------------------------------
6
HHSearch
21.53
22%
139
- C8 -
2FIP
-
VG4_BPPH2
A:
[64-99]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
L
A
D
I
T
F
Y
S
E
V
E
K
-
R
G
F
H
A
W
L
K
G
D
N
A
T
W
----------
R
E
V
H
V
Y
A
L
R
I
M
T
K
P
N
T
L
D
W
------
S
R
I
Q
K
P
R
--------------------------------------------------------------------------------------------------
7
HHSearch
18.59
36%
1646
- C2 -
2JMF
-
B:
[7-16]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
T
G
A
K
Q
P
P
S
Y
E
D
C
I
K
----------------------------------------------------
20
Fugue
18.02
19%
381
- C4 -
2MNU
-
?
B:
[1-26]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
S
S
P
I
Q
G
S
W
T
W
E
N
G
K
W
T
W
-----
K
G
I
I
R
L
E
-
Q
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------