@TOME V2.2
(Nov 2016)
Ref.
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : S38A3_HUMAN: (2015-12-10 )
MEAPLQTEMVELVPNGKHSEGLLPVITPMAGNQRVEDPARSCMEGKSFLQKSPSKEPHFTDFEGKTSFGMSVFNLSNAIMGSGILGLAYAMANTGIILFLFLLTAVALLSSYSIHLLLKSSGVVGIRAYEQLGYRAFGTPGKLAAALAITLQNIGAMSSYLYIIKSELPLVIQTFLNLEEKTSDWYMNGNYLVILVSVTIILPLALMRQLGYLGYSSGFSLSCMVFFLIAVIYKKFHVPCPLPPNFNNTTGNFSHVEIVKEKVQLQVEPEASAFCTPSYFTLNSQTAYTIPIMAFAFVCHPEVLPIYTELKDPSKKKMQHISNLSIAVMYIMYFLAALFGYLTFYNGVESELLHTYSKVDPFDVLILCVRVAVLTAVTLTVPIVLFPVRRAIQQMLFPNQEFSWLRHVLIAVGLLTCINLLVIFAPNILGIFGVIGATSAPFLIFIFPAIFYFRIMPTEKEPARSTPKILALCFAMLGFLLMTMSLSFIIIDWASGTSRHGGNH
Atome Classification :
(20 SA)
.........10........----------------20........30........40....-----....50........60------........70........80..-......-90........100.......110---........120.-.-.....130......--.140.-.......150...---.....160.--..----....170.......180.......190.......200.......210.......220.......230.....-...240.......250.......260----------......-.----270.......280.......290.......300.......310.......320...----....330.......340.......---350---........360.--......--370.......380.......390.....-------..400-----......------------.410......----.----420........430.......440.........450..----.....460.......470.......480.......490.......500..--------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MEAP
L
Q
T
E
M
V
E
LVPNGKHS----------------EGL
L
P
V
ITPMAGNQR
V
E
D
P
A
R
S
C
M
E
G
-----
K
S
F
L
Q
KSPSKEPHFTD------FEGKTSFG
M
S
V
F
N
L
S
N
A
I
MG
S
G
-
I
L
G
L
A
Y
-
A
M
AN
T
G
I
I
L
F
L
F
L
L
T
A
V
A
L
L
SS----
Y
S
I
H
L
L
L
KSS
G
V
-
V
-
G
I
R
A
Y
E
QLGYRAFG--TP
G
-
K
-
L
A
A
A
L
A
I
T
L
-
Q
N
I
---
G
A
M
S
S
Y
L
Y
I
--IK----SE
L
P
L
V
I
Q
T
F
LNLEEKTS
D
W
Y
MNG
N
Y
L
V
I
L
V
S
V
T
I
I
L
P
L
A
L
M
R
QLGYLGYSSGF
S
L
S
C
M
V
F
F
L
I
A
V
-
I
Y
K
KF-HVPCPLPPNFNNTTGN
F
S
H
V
E
I
V
K
E
K
----------
V
Q
L
Q
VE-P----EAS
A
F
CTP
S
Y
F
T
LNSQ
T
A
Y
T
I
P
I
M
A
F
A
F
VCHPE
V
L
P
I
Y
TELKDP
S
K
K
K
M
Q
H
I
SN
L
S
----
I
A
V
M
Y
I
M
Y
F
L
A
A
L
F
G
Y
L
T
F
YN
G
V
E
---
S
E
----
L
L
H
T
YSKV
D
P
F
D
--
V
L
I
L
C
V
--
R
V
A
V
L
T
A
V
T
L
T
V
P
I
V
L
F
P
V
R
R
A
I
Q
Q
MLF-------PNQ
E
F
-----
S
W
L
R
H
V
------------
L
I
A
V
G
L
L
T
C
I
----
N
----
L
L
-
V
I
FAP
N
I
L
G
I
F
G
VIGATSA--
P
F
L
I
F
I
F
P
A
I
F
Y
F
R----IMPTEKEPARS
T
P
K
I
L
A
L
C
F
A
M
L
G
F
L
L
M
T
MS
L
S
F
I
I
I
DWASGTSRHGGNH--------------------------------------
24
Fugue
90.06
19%
-140
- C3 -
4OR2
9
C562_ECOLX (first)
A:
[5-372]
----------
D
L
E
D
N
W
E
T
L
----------------
N
D
N
L
K
V
I
E
K
A
D
N
A
A
Q
V
K
D
A
L
T
K
M
R
A
A
-----
A
L
D
A
Q
K
A
T
P
--
P
K
L
E
D
-------
K
S
P
D
S
P
E
M
K
D
F
R
H
G
F
D
I
L
-
V
G
-
Q
I
D
D
A
L
-
K
L
A
N
E
G
----------------------------------------------------
K
V
-
K
-
E
A
Q
A
A
A
E
Q
L
-
K
T
T
---
R
N
A
Y
I
Q
K
Y
L
--
I
P
----
V
R
-------
Y
L
E
W
S
N
I
E
S
I
I
A
I
A
F
S
C
L
G
I
L
V
T
L
F
V
T
L
I
F
V
L
Y
R
D
T
P
V
V
K
S
S
S
----
R
E
L
C
Y
I
I
L
A
G
-
I
F
L
G
Y
-
V
C
P
F
T
L
I
----------------------------------------------
A
K
P
T
T
T
S
C
Y
L
Q
R
L
L
V
G
L
S
S
A
M
C
Y
S
A
L
V
T
K
T
N
R
I
A
R
I
L
A
R
K
P
R
F
M
S
A
W
A
Q
V
I
----
I
A
S
I
L
I
S
V
Q
L
T
L
V
V
T
L
I
I
M
E
P
------
P
M
----
P
I
L
S
Y
P
S
I
K
--
E
--
V
Y
L
I
C
N
TS
N
L
G
V
V
A
P
L
G
Y
N
G
L
L
I
M
S
C
T
Y
Y
A
F
K
---
T
-------
R
N
V
P
A
-----
N
F
N
E
A
K
------------
Y
I
A
F
T
M
Y
T
T
C
----
I
----
I
W
-
L
A
F
V
P
I
Y
F
G
----------------------------------------
S
N
Y
K
I
I
T
T
C
F
A
V
S
L
S
V
T
V
A
L
G
C
M
F
T
P
K
M
Y
I
I
I
A
K
P
E
------------------------------------------
25
Fugue
84.44
15%
-136
- C3 -
4Y9J
4
?
A:
[1-592]
-
T
I
T
A
R
H
T
Q
Y
S
H
A
K
T
G
G
F
S
Q
T
G
P
TLHNPYKDDPI
L
D
R
T
L
R
R
L
L
P
E
S
E
Y
M
R
V
A
A
D
L
S
K
F
G
D
R
I
T
S
E
V
E
H
L
G
R
Q
A
E
L
E
Q
P
R
L
E
H
QDAWGK
R
V
D
K
L
I
V
C
N
E
W
H
K
L
K
Q
I
C
A
E
E
G
-
V
I
S
I
G
Y
-
E
D
S
V
D
P
F
V
R
R
I
H
Q
V
A
K
L
F
L
F
S
P
SAGL
V
S
C
P
M
A
M
T
D
G
A
V
-
K
-
T
L
T
S
L
N
L
Y
G
--------
K
H
-
K
-
L
A
T
E
A
V
D
R
L
-
R
S
R
DPS
K
A
W
T
S
G
Q
W
M
--
T
E
KKGG
S
D
V
A
G
G
C
D
T
Y
A
V
Q
I
D
K
--
D
T
Y
R
L
H
G
Y
K
W
F
S
S
A
V
D
A
D
V
A
L
T
L
A
R
I
V
D
S
D
G
N
A
L
E
G
S
R
G
L
S
L
F
L
L
K
------------------
I
R
D
E
S
G
N
L
N
G
I
Q
M
V
R
L
K
NKLGTKQ
L
P
T
A
E
L
L
L
D
G
A
----
I
A
E
R
I
G
D
Q
G
R
G
V
A
G
I
S
N
M
L
N
I
T
R
I
H
N
A
V
A
S
L
G
Y
M
R
R
I
I
S
L
A
R
D
Y
S
T
K
R
V
V
F
G
Q
T
Q
S
KW
P
L
H
T
T
T
L
A
K
M
E
V
D
T
R
G
S
M
L
L
L
F
E
A
A
R
---
L
L
----
G
L
S
E
A
G
K
S
S
D
V
E
A
M
M
L
R
L
I
T
--
P
V
L
K
L
Y
A
G
K
Q
A
V
P
M
V
S
E
G
I
E
C
F
G
G
Q
G
Y
M
-------
E
D
T
G
L
-----
P
T
L
L
R
D
A
Q
V
T
P
I
WEGT
T
N
V
L
S
L
D
V
L
R
V
F
SGKE
N
----
I
L
-
L
A
F
G
K
R
V
E
Q
L
L
G
N
T
K
T
E
D
E
--
K
L
K
K
S
K
E
A
V
E
S
A
L
K
Q
L
Q
K
L
L
V
K
A
S
D
S
A
I
Q
G
E
T
R
I
D
S
V
A
R
H
I
A
F
T
I
A
R
I
Y
S
G
A
L
L
I
D
H
A
S
D
S
S
V
A
N
Q
S
D
I
E
V
A
Y
R
Y
C
CEQPLIDLRWEWFA
S
E
R
V
K
A
D
R
E
I
V
F
DNFT
27
Fugue
71.75
9%
-130
- C4 -
3GIA
7
Y609_METJA
A:
[3-435]
---------------------------------------------------------------------
L
K
N
K
K
L
S
L
W
E
A
V
S
------
M
A
V
G
V
M
I
G
A
S
I
F
S
I
----------
F
G
V
G
A
-
K
I
A
G
R
N
L
P
E
T
F
I
L
S
G
I
Y
A
L
L
V
A
----
Y
S
Y
T
K
L
G
A
------------------------------------
K
I
-
V
S
N
---
A
G
P
I
A
F
I
H
K
--
A
I
----
G
D
---------
N
I
I
T
G
A
L
S
I
L
L
W
M
S
Y
V
I
S
I
A
L
F
A
K
G
F
A
G
Y
F
L
P
L
I
N
A
P
I
N
T
F
N
I
A
I
T
E
I
G
I
V
A
F
F
T
-
A
L
N
F
F
-
G
S
K
A
V
G
R
A
E
F
F
I
V
L
V
K
L
L
I
L
G
L
F
I
F
A
----------
G
L
I
T
I
H
-
P
----
S
Y
V
I
P
D
L
A
P
S
A
V
S
G
M
I
F
A
S
A
I
--
F
F
L
S
Y
M
G
F
G
V
I
T
N
A
S
E
H
I
E
N
P
K
K
N
V
P
R
A
I
F
I
S
I
----
L
I
V
M
F
V
Y
V
G
V
A
I
S
A
I
G
N
L
P
I
D
E
L
I
K
A
S
E
N
----
A
L
A
V
A
A
K
P
F
L
G
N
--
L
G
F
L
L
I
--
S
I
G
A
L
F
S
I
S
S
A
M
N
A
T
I
Y
G
G
A
N
V
A
Y
S
L
A
K
D
GELPEF
F
E
R
K
V
-----
W
F
K
S
T
E
------------
G
L
Y
I
T
S
A
L
G
V
----
L
----
F
A
-
L
L
F
N
M
E
G
V
A
S
I
T
S
A
V
F
M
V
I
--
Y
L
F
V
I
L
S
H
Y
I
L
I
D
E
----
V
G
G
R
K
E
I
V
I
F
S
F
I
V
V
L
G
V
F
L
L
L
L
Y
Y
Q
W
I
T
N
R
F
V
F
Y
G
I
I
A
T
F
I
G
V
L
I
F
E
I
I
Y
R
K
V
TK
R
T
F
S
NNMYVKS---------------------
11
HHSearch
70.70
12%
-126
- C4 -
3L1L
2
ADIC_ECO57
A:
[7-380]
-----------------------------------------------------------------------------------------
A
H
K
V
G
L
I
P
V
T
L
M
V
S
G
A
I
M
G
S
G
-
V
F
L
L
P
A
-
N
L
A
S
T
G
G
-
I
A
I
Y
G
W
L
V
T
I
I
G
A
L
----
G
L
S
M
V
Y
A
K
M
S
F
L
-
D
P
S
P
G
G
S
Y
A
Y
A
R
R
C
F
G
--
P
F
L
-
G
-
Y
Q
T
N
V
L
Y
W
L
-
A
C
W
---
I
G
N
I
A
M
V
V
I
--
G
V
----
G
Y
L
S
Y
F
F
P
I
L
K
D
------
P
W
V
----
L
T
I
T
C
V
V
V
L
W
I
F
V
L
L
N
I
V
G
P
K
M
I
T
R
V
Q
A
V
A
T
V
L
A
L
I
P
I
V
G
I
-
A
V
F
G
W
-
F
W
F
R
G
E
T
Y
M
---------------------------
A
--------------------------
A
I
Q
S
T
L
N
V
T
L
W
S
F
I
G
V
E
S
A
S
V
A
A
G
V
V
K
N
P
-
K
R
N
V
P
I
A
T
I
G
G
----
V
L
I
A
A
V
C
Y
V
L
S
T
T
A
I
M
G
M
I
P
N
A
A
L
---
R
V
SAS-
P
F
G
D
A
A
R
M
A
L
G
D
--
T
A
G
A
I
V
--
S
F
C
A
A
A
G
C
L
G
S
L
G
G
W
T
L
L
A
G
Q
T
A
K
A
A
A
D
-------
D
G
L
F
P
PIFAR
V
N
K
A
G
T
------------
P
V
A
G
L
I
I
V
G
I
----
L
M
T
I
F
Q
L
-
S
S
I
S
P
N
A
T
K
E
F
G
L
V
S
S
V
S
V
I
F
T
L
V
P
Y
L
Y
T
C
A
A
L
L
L
----
L
G
H
G
H
F
G
K
A
R
P
A
Y
L
A
V
T
T
I
A
F
L
Y
C
I
W
A
V
V
G
S
G
A
K
E
V
M
W
S
F
V
T
L
M
V
I
T
A
M
Y
--------------------------------------
30
Fugue
68.18
16%
-125
- C2 -
1DMU
2
T2B1_BACIU
A:
[1-299]
--------------------------------------------------------------------------------------------------
M
Y
N
L
H
R
E
K
I
F
M
S
-
Y
N
Q
N
K
Q
-
Y
L
E
D
N
P
E
I
Q
E
K
I
E
L
Y
G
L
N
L
L
N
E
----
V
I
S
D
N
E
E
E
I
R
A
D
-
Y
-
N
E
A
N
F
L
H
P
F
W
M
N
Y
P
PL
D
R
G
-
K
-
M
P
K
G
D
Q
I
P
W
-
I
E
V
---
G
E
K
A
-------
V
G
----
S
K
L
T
R
L
V
S
Q
R
E
D
I
T
V
R
E
I
G
L
P
T
G
P
D
E
R
Y
L
L
T
S
P
T
I
Y
S
L
------------
T
N
G
F
T
D
S
I
M
M
F
V
D
I
K
S
-
V
G
P
R
D
S
D
Y
D
L
V
L
S
P
N
Q
V
S
G
N
G
D
W
A
Q
L
E
G
G
I
Q
N
----------
N
Q
Q
T
I
Q
G
P
----
R
S
S
Q
I
F
L
P
T
I
P
P
L
Y
I
L
S
D
G
T
-----
I
A
P
V
V
H
L
F
I
K
P
I
Y
A
M
R
S
L
T
K
G
D
T
G
Q
S
L
Y
K
I
K
----
L
A
S
V
P
N
G
L
G
L
F
C
N
P
G
Y
A
F
--
D
S
A
Y
---
K
F
----
L
F
R
P
G
K
D
D
R
T
K
S
--
L
L
Q
K
R
V
--
R
V
D
L
R
V
L
D
K
I
G
P
R
V
M
T
I
D
M
D
K
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
HHSearch
67.07
11%
-138
- C4 -
3GIA
6
Y609_METJA
A:
[3-367]
---------------------------------------------------------------------------------
L
------
K
N
K
K
L
S
L
W
E
A
V
S
M
A
V
G
V
M
I
G
A
S
-
I
F
S
I
F
G
V
G
A
K
I
A
G
R
-
N
L
P
E
T
F
I
L
S
G
I
Y
A
L
----
L
V
A
Y
S
Y
T
K
L
G
A
K
I
V
-
S
N
A
G
P
I
A
F
I
H
K
A
I
G
--
D
N
I
I
T
-
G
A
L
S
I
L
L
W
M
-
S
Y
V
---
I
S
I
A
L
F
A
K
G
--
F
A
----
G
Y
F
L
P
L
I
N
A
P
I
N
------
T
F
---
N
-
I
A
I
T
E
I
G
I
V
A
F
F
T
A
L
N
F
F
G
S
K
A
V
G
R
A
E
F
F
I
V
L
V
K
L
L
I
L
G
L
F
-
I
F
A
G
L
-
I
T
I
H
P
S
-------------------------------
Y
V
I
P
-------
D
L
---
A
P
S
A
V
----
S
G
M
I
F
A
S
A
I
F
F
L
S
Y
M
G
F
G
V
I
T
N
A
S
E
H
I
E
N
P
-
K
K
N
V
P
R
A
I
F
I
S
----
I
L
I
V
M
F
V
Y
V
G
V
A
I
S
A
I
G
N
L
P
I
D
E
L
---
I
K
A
SEN
A
L
A
V
A
A
K
P
F
L
G
N
--
L
G
F
L
L
I
--
S
I
G
A
L
F
S
I
S
S
A
M
N
A
T
I
Y
G
G
A
N
V
A
Y
S
L
A
K
-------
D
G
E
L
P
EFFER
K
V
W
F
K
S
------------
T
-
E
G
L
Y
I
T
S
A
----
L
----
G
V
L
F
A
L
L
F
N
M
E
G
V
A
S
I
T
S
A
--
V
--
F
M
V
I
Y
L
F
V
I
L
S
H
Y
I
----
L
I
D
E
V
G
G
R
K
E
I
V
I
F
S
F
I
V
V
L
G
V
F
L
L
L
L
Y
Y
Q
W
I
T
N
R
F
V
F
Y
G
I
I
A
T
F
I
G
V
L
I
--------------------------------------
28
Fugue
62.79
14%
-86
- C3 -
1U19
8
OPSD_BOVIN
A:
[4-349]
M
N
G
T
E
G
P
N
F
--
Y
V
P
F
S
N
K
T
----------------
G
V
V
---------------------------------
R
S
P
F
E
A
P
Q
Y
Y
---------------------------------
L
A
E
-
P
W
Q
F
S
M
L
A
A
Y
M
F
L
L
I
M
L
G
F
P
I
N
----
F
L
T
L
Y
V
T
V
Q
H
K
------------------------
K
-
L
R
T
P
L
N
Y
I
L
-
L
N
L
---
A
V
A
D
L
F
M
V
F
GG
F
T
----
T
T
L
Y
T
S
L
H
G
Y
F
V
F
G
P
T
G
C
N
L
E
G
F
F
A
T
L
G
G
E
I
A
L
W
S
L
V
V
L
A
I
E
R
Y
V
V
V
C
K
P
M
S
N
F
R
F
G
E
N
H
A
I
M
G
V
A
-
F
T
W
V
M
-
A
L
A
C
A
A
P
P
L
V
G
-----
W
S
R
--
Y
I
P
E
G
----------
M
Q
C
S
C
G
-
I
DYYT
P
H
E
E
T
N
N
E
S
F
V
I
Y
M
F
V
V
H
F
I
I
P
L
I
V
I
F
F
C
Y
G
Q
L
V
F
T
V
K
E
A
A
A
Q
Q
Q
E
S
A
T
T
Q
K
A
E
K
E
----
V
T
R
M
V
I
I
M
V
I
A
F
L
I
C
W
L
P
Y
A
G
V
A
F
---
Y
I
----
F
T
H
Q
G
S
---
D
F
G
--
P
I
F
M
T
I
--
P
A
F
F
A
K
T
S
A
V
Y
N
P
V
I
Y
I
M
M
-----------------
N
K
Q
F
-----
R
N
C
M
V
T
------------
T
L
C
C
G
K
------------------------
N
P
L
G
D
D
E
A
S
T
T
--
V
--------------------
S
K
T
E
T
S
Q
V
A
P
A
--------------------------------------------------------------------------
3
PsiBlast_PDB
37.45
26%
-89
* C5 *
3K1Q
-
?
A:
[1073-1170]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
--
T
P
G
-
N
V
I
S
V
A
G
A
A
A
L
-
Q
Y
I
---
L
A
N
Q
E
F
L
L
Q
--
F
T
----
P
T
L
P
G
I
F
D
V
F
L
T
T
L
G
Q
P
P
--
V
P
R
G
S
F
T
I
T
P
P
P
T
T
V
A
L
N
M
P
P
P
R
Q
L
D
F
T
D
V
G
N
D
A
R
I
T
C
D
P
Y
Y
Q
L
A
V
C
I
F
K
D
G
-
Q
Y
V
R
V
N
P
E
K
A
S
V
V
T
N
A
P
N
R
D
L
H
F
V
L
D
----------
L
A
D
N
H
V
-
L
----
L
Y
L
C
D
V
T
P
S
G
L
G
D
R
I
A
F
P
I
V
D
I
Y
R
I
A
F
P
R
N
T
P
V
R
A
S
L
P
Y
T
G
G
G
A
H
L
T
S
G
G
N
P
F
M
S
L
----
T
T
P
P
A
V
L
P
A
G
V
A
L
A
A
L
S
T
S
V
A
T
Q
Y
---
P
T
----
Y
T
L
P
A
G
V
Y
E
Y
V
I
--
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
36.04
26%
-83
- C5 -
3IYL
-
?
W:
[1073-1170]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
--
T
P
G
-
N
V
I
S
V
A
G
A
A
A
L
-
Q
Y
I
---
L
A
N
Q
E
F
L
L
Q
--
F
T
----
P
T
L
P
G
I
F
D
V
F
L
T
T
L
G
Q
P
P
--
V
P
R
G
S
F
T
I
T
P
P
P
T
T
V
A
L
N
M
P
P
P
R
Q
L
D
F
T
D
V
G
N
D
A
R
I
T
C
D
P
Y
Y
Q
L
A
V
C
I
F
K
D
G
-
Q
Y
V
R
V
N
P
E
K
A
S
V
V
T
N
A
P
N
R
D
L
H
F
V
L
D
----------
L
A
D
N
H
V
-
L
----
L
Y
L
C
D
V
T
P
S
G
L
G
D
R
I
A
F
P
I
V
D
I
Y
R
I
A
F
P
R
N
T
P
V
R
A
S
L
P
Y
T
G
G
G
A
H
L
T
S
G
G
N
P
F
M
S
L
----
T
T
P
P
A
V
L
P
A
G
V
A
L
A
A
L
S
T
S
V
A
T
Q
Y
---
P
T
----
Y
T
L
P
A
G
V
Y
E
Y
V
I
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
HHSearch
35.12
18%
153
- C4 -
2WWB
-
SC61G_CANFA
B:
[22-54]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
K
R
C
T
K
P
D
R
K
E
F
Q
K
I
A
M
A
T
----
A
----
I
G
F
A
I
M
G
F
I
G
F
F
V
K
L
I
H
I
P
---
I
N
----
N
I
I
V
G
G
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
HHSearch
34.69
19%
184
* C4 *
3MP7
-
SECE_PYRFU
B:
[19-50]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
V
T
K
K
P
N
W
A
T
Y
K
R
A
A
K
I
T
----
G
----
L
G
I
I
L
I
G
L
I
G
M
L
I
R
I
V
G
I
L
---
I
L
----
G
G
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
HHSearch
34.55
9%
-85
- C4 -
2JLN
-
?
A:
[24-186]
-----------------------------------------------------------------------------------------
E
R
S
V
G
P
F
S
L
A
A
I
W
F
A
M
A
I
Q
V
A
I
F
I
A
A
G
Q
-
M
T
S
S
F
Q
V
W
Q
V
I
V
A
I
A
A
G
C
T
I
A
V
----
I
L
L
F
F
T
Q
S
A
A
I
R
-
W
-
G
-
I
N
F
T
V
A
A
R
M
P
F
G
--
I
R
G
-
S
-
L
I
P
I
T
L
K
A
L
-
L
S
L
---
F
W
F
G
F
Q
T
W
L
--
G
A
----
L
A
L
D
E
I
T
R
L
L
T
G
F
T
--------
N
L
-
P
L
W
I
V
I
F
G
A
I
Q
V
V
T
T
-
F
Y
G
I
T
F
I
R
W
M
N
V
F
A
S
P
V
L
L
A
M
G
V
Y
M
-
V
Y
L
M
L
-
D
G
A
D
V
S
L
G
E
V
M
S
M
G
G
E
N
P
G
M
P
F
S
T
A
I
----------
M
I
F
V
G
G
-
W
----
I
A
V
V
V
S
I
H
D
I
V
K
E
C
K
V
D
P
N
A
S
R
E
G
Q
T
K
A
D
A
R
Y
A
T
A
Q
W
L
G
M
V
P
A
S
I
I
F
G
F
I
G
A
A
S
M
V
----
L
V
G
E
W
N
P
V
I
A
I
T
E
V
V
G
G
V
S
I
P
M
A
I
---
L
F
----
Q
V
F
V
L
L
A
T
W
S
T
N
--
P
A
A
N
L
L
--
S
P
A
Y
T
L
C
S
T
F
P
R
V
F
T
F
K
T
G
V
I
V
S
A
V
V
G
L
-------
L
M
M
P
W
-----
Q
F
A
G
V
L
------------
N
T
F
L
N
L
L
A
S
A
----
L
----
G
P
-
L
A
G
I
M
I
S
D
Y
F
L
V
R
R
R
R
I
S
L
--
H
D
L
Y
R
T
K
G
I
Y
T
Y
W
R
----
G
V
N
W
V
A
L
A
V
Y
A
V
A
L
A
V
S
F
L
T
P
D
L
M
F
V
T
G
L
I
A
A
L
L
L
H
I
P
A
M
R
W
V
A
K
T
F
P
L
F
--------------------------------------
14
HHSearch
33.92
13%
-71
- C4 -
3DH4
1
?
A:
[52-175]
----------------------------------------------------------------------------------------
A
G
K
S
L
P
W
W
A
V
G
A
S
L
I
A
A
N
I
S
A
E
Q
F
I
G
M
S
G
-
S
G
Y
S
I
G
L
A
I
A
S
Y
-
E
W
M
S
A
I
T
L
I
----
I
V
G
K
Y
F
L
P
I
F
I
E
-
K
-
G
I
Y
T
I
P
E
F
V
E
K
R
F
N
--
K
K
L
-
K
-
T
I
L
A
V
F
W
I
S
L
Y
I
F
---
V
N
L
T
S
V
L
Y
L
--
G
G
----
L
A
L
E
T
I
L
G
I
----
P
---------
L
-
M
Y
S
I
L
G
L
A
L
F
A
L
V
Y
S
I
------
V
V
W
T
D
V
I
Q
V
F
F
L
V
L
G
G
F
M
T
-
T
Y
M
A
V
-
S
F
I
G
G
T
D
G
W
F
A
G
V
S
K
M
V
D
A
A
P
G
H
F
E
M
----------
I
L
D
Q
S
N
-
P
----
Q
Y
M
N
L
P
G
I
A
V
L
I
G
G
L
W
V
A
N
L
Y
Y
W
G
F
N
Q
Y
I
I
Q
R
T
L
A
A
K
S
V
S
E
A
Q
K
G
I
V
F
A
A
F
L
K
L
I
V
----
P
F
L
V
V
L
P
G
I
A
A
Y
V
I
T
S
D
P
Q
L
M
A
S
L
---
G
D
----
I
A
A
T
N
L
P
S
A
A
N
A
--
D
K
A
Y
P
W
--
L
T
Q
F
L
P
V
G
V
K
G
V
V
F
A
A
L
A
A
A
I
V
S
S
L
A
S
M
-------
L
N
S
T
A
-----
T
I
F
T
M
D
------------
I
Y
K
E
Y
I
S
P
D
S
----
G
----
D
H
-
K
L
V
N
V
G
R
T
A
A
V
V
A
L
I
I
A
C
L
--
I
A
P
M
L
G
G
I
G
Q
A
F
Q
Y
----
I
Q
E
Y
T
G
L
V
S
P
G
I
L
A
V
F
L
L
G
L
F
W
K
K
T
T
S
K
G
A
I
I
G
V
V
A
S
I
P
F
A
L
F
L
K
F
M
P
L
S
--------------------------------------
9
PsiBlast_CBE
31.61
61%
445
* C6 *
4PG3
2
?
C:
[419-439]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
I
C
G
K
E
V
L
N
A
Y
T
E
L
N
D
P
F
K
Q
K
E
C
F
L
D
S
A
F
----
C
T
S
L
E
Y
G
L
P
P
T
G
G
L
G
L
G
I
D
R
I
T
M
F
---
L
T
----
N
K
N
S
I
K
D
V
I
L
F
P
--
T
M
R
P
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_CBE
30.44
61%
444
- C6 -
4PG3
2
?
B:
[419-439]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
I
C
G
K
E
V
L
N
A
Y
T
E
L
N
D
P
F
K
Q
K
E
C
F
L
D
S
A
F
----
C
T
S
L
E
Y
G
L
P
P
T
G
G
L
G
L
G
I
D
R
I
T
M
F
---
L
T
----
N
K
N
S
I
K
D
V
I
L
F
P
--
T
M
R
P
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_CBE
30.22
61%
457
- C6 -
4YCV
1
?
D:
[420-440]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
I
C
G
K
E
V
L
N
A
Y
T
E
L
N
D
P
F
K
Q
K
E
C
F
S
A
F
C
T
----
S
L
E
Y
G
L
P
P
T
G
G
L
G
L
G
I
D
R
I
T
M
F
L
T
---
N
K
----
N
S
I
K
D
V
I
L
F
P
T
M
--
R
P
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_CBE
29.37
61%
442
- C6 -
4PG3
2
?
D:
[419-439]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
I
C
G
K
E
V
L
N
A
Y
T
E
L
N
D
P
F
K
Q
K
E
C
F
L
D
S
A
F
----
C
T
S
L
E
Y
G
L
P
P
T
G
G
L
G
L
G
I
D
R
I
T
M
F
---
L
T
----
N
K
N
S
I
K
D
V
I
L
F
P
--
T
M
R
P
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
28.69
61%
483
- C6 -
4YCV
1
?
A:
[420-440]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
I
C
G
K
E
V
L
N
A
Y
T
E
L
N
D
P
F
K
Q
K
E
C
F
K
L
L
D
S
----
A
F
C
T
S
L
E
Y
G
L
P
P
T
G
G
L
G
L
G
I
D
R
I
T
---
M
F
----
L
T
N
K
N
S
I
K
D
V
I
L
--
F
P
T
M
R
P
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_CBE
28.19
61%
478
- C6 -
4YCV
1
?
C:
[420-440]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
I
C
G
K
E
V
L
N
A
Y
T
E
L
N
D
P
F
K
Q
K
E
C
F
L
D
S
A
F
----
C
T
S
L
E
Y
G
L
P
P
T
G
G
L
G
L
G
I
D
R
I
T
M
F
---
L
T
----
N
K
N
S
I
K
D
V
I
L
F
P
--
T
M
R
P
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
28.18
61%
448
- C6 -
4PG3
2
?
A:
[419-439]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
I
C
G
K
E
V
L
N
A
Y
T
E
L
N
D
P
F
K
Q
K
E
C
F
L
D
S
A
F
----
C
T
S
L
E
Y
G
L
P
P
T
G
G
L
G
L
G
I
D
R
I
T
M
F
---
L
T
----
N
K
N
S
I
K
D
V
I
L
F
P
--
T
M
R
P
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------