@TOME V2.2
(Nov 2016)
Ref.
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : T0765: (2014-05-06 )
MMVMKRPSLRQFSWLLGGSLLLGALFWLWLAVQQQEATLAIRPVGQGIGMPDGFSVWHHLDANGIRFKSITPQKDGLLIKFDSTAQGAAAKEVLGRALPHGYIIALLEDDNSPTAWLSRLRDAPHRLG
Atome Classification :
(20 SA)
---------------------------------------------------------------------------......---------...10......----..20........30.----....-...40...-----.....50--.....-...-.60......---..70-----.---------.-------.--------.-----....80.-.......90-........100.......110.......120......-----------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
---------------------------------------------------------------------------MMVMKR---------PS
L
R
Q
F
S
W
L
LG----
G
S
L
L
L
G
A
L
F
W
L
W
L
A
V
----QQQE-
A
T
L
A
I
R
PV-----GQGIGM---PDG
F
S
-
V
W
H
-HLDAN
G
I
R
F
---KSIT-----P---------Q-------K--------D-----
G
L
L
I
K
FD-STAQ
G
A
A
A
K
-
E
V
L
G
R
ALPH
G
Y
I
I
A
L
L
EDDNS
P
T
A
W
L
S
R
L
RDAPHRLG-----------------------------------------------------
25
HHSearch
75.53
16%
-118
- C4 -
2DNP
-
RBM14_HUMAN
A:
[77-145]
------------------------------------------------------------------------------------------------------------------------------
N
T
-
W
K
I
F
V
G
N
V
-----
S
A
A
C
T
S
------
Q
E
-
L
R
S
-
L
F
E
R
R
G
-
R
V
---
I
E
C
D
-----
V
---------
V
-------
K
--------
D
-----
Y
A
F
V
H
M
E
-
K
E
A
D
A
K
A
A
I
-
A
Q
L
N
G
K
E
V
K
G
K
R
I
N
V
E
--------------------------------------------------------------------------
21
SP3
75.17
10%
-103
- C4 -
1XEW
-
?
Y:
[1012-1173]
--------------------------------VFMRTFEAISRNFSEIFAKLSPGGSARLILENPEDPFSGGLEI
E
A
K
P
A
G
---------
K
D
V
K
R
I
E
A
M
S
G
----
G
E
K
A
L
T
A
L
A
F
V
F
A
I
Q
----
K
F
K
P
A
P
F
Y
L
F
D
E
I
-----
D
A
H
L
D
D
---
A
N
V
K
R
-
V
A
D
-
L
I
K
E
S
----------------
S
---------
K
-------
E
--------
S
-----
Q
F
I
V
I
T
L
-
R
D
V
M
M
A
N
A
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-
K
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I
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M
G
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S
K
V
V
S
L
S
L
E
K
A
--
M
K
I
L
E
E
I
R
K
---
K
Q
G
W----------------------------------------------------
5
Fugue
74.76
13%
-95
* C3 *
1J0S
-
IL18_HUMAN
A:
[1-157]
---------------------------------------------------------YFGKL
E
S
K
L
S
V
I
R
N
LND
Q
V
L
F
I
D
Q
---------
G
N
R
P
L
F
E
D
M
T
D
----
S
D
C
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N
A
P
R
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I
F
I
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----
M
Y
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-
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P
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G
M
A
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-----
T
--
I
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---
K
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-
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E
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I
I
S
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---
K
E
M
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-----
P
---------
P
-------
D
--------
N
IKDTK
S
D
I
I
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F
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-
R
S
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G
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D
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-
M
Q
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E
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Y
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L
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K
E
D
E
L
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I
M
F
T
V
Q
N
E
D---------------------------------------------
32
HHSearch
73.23
17%
-100
- C4 -
2DGU
-
HNRPQ_HUMAN
A:
[335-405]
-----------------------------------------------------------------------------------------------------------------------------
A
K
V
-
K
V
L
F
V
R
N
L
-----
A
N
T
V
T
E
---
E
---
I
-
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E
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-
A
F
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Q
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G
-
K
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---
E
R
V
K
-----
K
---------
L
-------
K
--------
D
-----
Y
A
F
I
H
F
D
-
E
R
D
G
A
V
K
A
M
-
E
E
M
N
G
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D
L
E
G
E
N
I
E
I
V
F
-------------------------------------------------------------------------
33
HHSearch
71.68
14%
-113
- C4 -
2JVR
-
A:
[25-103]
----------------------------------------------------------------------------------------------------------------------------
P
A
K
R
-
Y
R
I
T
M
K
N
L
-----
P
E
G
C
S
W
------
Q
D
-
L
K
D
-
L
A
R
E
N
S
L
E
T
---
T
F
S
S
-----
V
NTRD-----
F
-------
D
--------
G
-----
T
G
A
L
E
F
P
-
S
E
E
I
L
V
E
A
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-
E
R
L
N
N
I
E
F
R
G
S
V
I
T
V
E
R
D
D
-----------------------------------------------------------------------
17
SP3
71.22
14%
-87
- C4 -
1U7P
-
MGDP1_MOUSE
A:
[1-164]
---------------------------------------------------------------------------
M
T
R
L
P
K
-----------------
L
A
V
------
F
D
L
D
Y
T
L
W
P
F
W
V
D
----
T
H
V
D
-
P
P
F
H
K
S
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N
I
QLY
P
E
V
P
E
-
V
L
G
-
R
L
Q
S
L
G
V
P
------------------------------------------------
V
A
A
A
S
-
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A
N
-
Q
L
L
E
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D
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F
I
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E
I
Y
P
G
S
K
V
T
H
F
E
R
L
H
H
---
K
T
G
VPFSQ
M
V
F
F
D
DE
N
R
N
I
I
D
V
G
R
L
GVT
C
I
H
I
R
DGMS
L
Q
T
L
T
Q
G
L
E
T
F
A
K
A
Q
A
GL-
23
HHSearch
69.69
10%
-107
- C4 -
2DGT
-
RBM4B_HUMAN
A:
[76-146]
------------------------------------------------------------------------------------------------------------------------------
A
S
-
T
K
L
H
V
G
N
I
-----
S
P
T
C
T
N
------
Q
E
-
L
R
A
-
K
F
E
E
Y
G
-
P
V
---
I
E
C
D
-----
I
---------
V
-------
K
--------
D
-----
Y
A
F
V
H
M
E
-
R
A
E
D
A
V
E
A
I
-
R
G
L
D
N
T
E
F
Q
G
K
R
M
H
V
Q
L
S
------------------------------------------------------------------------
29
HHSearch
68.95
14%
-95
- C4 -
2DO4
-
SART3_HUMAN
A:
[799-877]
------------------------------------------------------------------------------------------------------------------------------
E
K
-
H
K
L
F
I
S
G
L
-----
P
F
S
C
T
K
------
E
E
-
L
E
E
-
I
C
K
A
H
G
-
T
V
---
K
D
L
R
-----
L
---------
V
TNRAGKP
K
--------
G
-----
L
A
Y
V
E
Y
E
-
N
E
S
Q
A
S
Q
A
V
-
M
K
M
D
G
M
T
I
K
E
N
I
I
K
V
A
I
S
N
-----------------------------------------------------------------------
9
Fugue
68.22
20%
-16
- C4 -
4EYT
-
?
A:
[10-106]
-------------------------------------------------------------------------------
K
Q
---------
N
C
L
I
K
I
I
N
I
P
Q
----
G
T
L
-----------------
K
A
E
-
V
V
L
A
V
R
H
L
-----
G
---------
Y
E
F
Y
-
C
D
Y
-
I
D
G
Q
A
M
I
R
F
---
Q
N
S
D
-----
E
---------
Q
-------
R
--------
L
-----
A
I
Q
-
K
L
L
-
N
H
N
N
N
K
L
Q
I
-
E
I
R
G
---
Q
I
C
D
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I
S
T
I
P
E
D
E
E
K
N
Y
W
N
Y
I
K
F
K
K
N
---------------------------------------------------------
37
HHSearch
66.80
17%
-84
- C4 -
2ADC
-
A:
[151-216]
-------------------------------------------------------------------------------------------------------------------------------
S
-
A
T
L
H
L
S
N
I
-----
P
P
S
V
S
------
E
E
D
-
L
K
V
-
L
F
S
S
N
G
G
V
V
---
K
G
F
K
-----
F
FQK------
D
-------
R
--------
K
-----
M
A
L
I
Q
M
G
-
S
V
E
E
A
V
Q
A
L
-
I
D
L
H
N
H
D
L
G
E
--------------------------------------------------------------------------------
43
HHSearch
66.23
11%
-92
- C4 -
2DGX
-
A:
[553-632]
------------------------------------------------------------------------------------------------------------------------------
N
G
-
A
D
V
Q
V
S
N
I
-----
D
Y
R
L
S
R
---
K
E
L
Q
Q
L
L
Q
E
-
A
F
A
R
H
G
-
K
V
---
K
S
V
E
-----
L
---------
S
PHTDY--
Q
--------
L
-----
K
A
V
V
Q
M
E
-
N
L
Q
D
A
I
G
A
V
-
N
S
L
H
R
Y
K
I
G
S
K
K
I
L
V
S
L
A
------------------------------------------------------------------------
34
HHSearch
64.28
16%
-76
- C4 -
3OFF
-
A:
[16-74]
-----------------------------------------------------------------------------------------------------------------------------------
V
S
V
T
G
N
-----
P
T
R
E
E
S
---
D
T
I
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-
L
W
Q
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W
N
N
H
I
Q
A
---
E
R
Y
M
-----
V
---------
D
-------
D
--------
N
-----
R
A
I
F
L
F
K
-
D
G
T
Q
A
W
D
A
K
-
D
F
L
I
E
-------------------------------------------------------------------------------------
31
HHSearch
61.12
14%
-97
- C4 -
4A8X
-
RNPS1_HUMAN
A:
[159-233]
------------------------------------------------------------------------------------------------------------------------------
K
P
-
T
K
V
H
I
G
R
L
-----
T
R
N
V
T
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---
D
---
H
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E
-
I
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S
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Y
G
-
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I
---
K
M
I
D
-----
M
P
V
ERMHPHL
S
-------
K
--------
G
-----
Y
A
Y
V
E
F
E
-
N
P
D
E
A
E
K
A
L
-
K
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M
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Q
I
D
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Q
E
I
-----------------------------------------------------------------------------
30
HHSearch
60.46
12%
-80
- C4 -
3MDF
-
PPIE_HUMAN
A:
[3-70]
-----------------------------------------------------------------------------------------------------------------------------
T
T
K
-
R
V
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Y
V
G
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-----
A
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D
------
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A
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A
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---
T
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-----
I
P
L
DYETEK-
H
-------
R
--------
G
-----
F
A
F
V
E
F
E
-
L
A
E
D
A
A
A
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I
-
D
N
M
N
E
S
------------------------------------------------------------------------------------
42
HHSearch
56.75
12%
-107
* C4 *
3BS9
-
TIA1_HUMAN
A:
[6-77]
-------------------------------------------------------------------------------------------------------------------------------
H
-
F
H
V
F
V
G
D
L
-----
S
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E
I
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------
A
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A
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F
G
-
R
I
---
S
D
A
R
-----
V
---------
V
-------
K
D
MATGKSK
G
-----
Y
G
F
V
S
F
F
-
N
K
W
D
A
E
N
A
I
-
Q
Q
M
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G
Q
W
L
G
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R
Q
------------------------------------------------------------------------------
18
SP3
56.56
11%
-91
- C4 -
1KZF
-
ESAI_ERWST
A:
[1-210]
M
L
E
L
F
D
V
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Y
E
E
L
Q
T
TFS
D
R
L
G
W
E
V
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C
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Q
GMESDEFDGPG
T
R
Y
I
L
G
I
C
EGQLV
C
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V
R
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S
LDRPNMITHTFQHCFS
D
V
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A
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RFF
V
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K
A
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G
EHYP
I
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Q
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L
A
M
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N
W
A
Q
N
----
N
A
Y
G
-
N
I
Y
T
I
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S
------------------
R
A
-
M
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K
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I
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Q
I
KVI
K
E
A
F
-----
L
---------
T
-------
E
--------
K
E
R
---
I
Y
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-
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--------
C
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P
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A
V
T
T
W
-------
P
L
T
L
P
V----------------------------------------------------
38
HHSearch
56.14
15%
-85
- C4 -
2E44
-
IF2B3_HUMAN
A:
[80-150]
-------------------------------------------------------------------------------------------------------------------------------
I
-
R
K
L
Q
I
R
N
I
-----
P
P
H
L
Q
W
---
E
V
----
L
D
S
-
L
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V
Q
Y
G
-
V
V
---
E
S
C
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Q
V
N
TD
S
---------
E
-------
T
--------
A
-----
V
V
N
V
T
Y
S
-
S
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A
L
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N
G
F
Q
L
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N
F
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L
K
----------------------------------------------------------------------------
19
SP3
53.68
12%
-45
- C4 -
1GPU
-
TKT1_YEAST
A:
[535-680]
-------------------------------------------------------------------------------
E
G
---------
S
S
I
E
S
A
S
--
K
G
----
G
Y
V
L
----------
Q
----
D
V
A
N
-
P
D
I
I
L
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A
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-------
G
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S
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E
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A
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-----
L
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P
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D
-------------------
F
F
-
T
F
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--
P
L
-
E
Y
R
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H
---
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GFT
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A
F
Y
KG
D
K
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I
SPLKKAF-----
13
Fugue
53.63
15%
-52
- C4 -
2RBG
-
?
A:
[3-126]
--------------------------------------------------------------------YK
N
I
L
T
L
I
S
V
N
N
D
---------
N
F
E
N
Y
F
R
K
I
F
L
----
D
V
R
S
S
G
S
K
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T
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I
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V
F
TEIQ
Y
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-
V
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---
G
Y
E
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N
L
E
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-----
S
---------
E
-------
V
--------
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G
L
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V
Y
C
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-
D
E
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---
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C
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L
S
------------------------------------------------------------------
15
SP3
53.34
13%
-40
* C5 *
1BCC
3
UCRI_CHICK
E:
[1-196]
------------------------------------------------------------SHTD
I
K
V
P
N
FSDYRR
P
P
D
D
Y
S
TKSSRESD-
P
S
R
K
G
F
S
Y
L
V
T
----
A
V
T
T
L
G
V
A
Y
A
A
K
N
V
V
----
T
Q
F
V
-
S
S
M
--
S
A
S
-----
A
D
V
L
A
M
---
S
K
I
E
I
-
K
L
S
-
D
I
P
E
G
--
K
N
---
M
A
F
K
-----
W
---------
R
-------
G
--------
K
-----
P
L
F
V
R
H
R
-
T
K
K
E
I
D
Q
E
A
-
A
V
E
V
S
Q
L
R
D
P
---
Q
H
D
L
E
R
V
K
K
P
E
W
V
I
-
L
I
G
V
C
T
H
L
G
C
V
P
I
A
NAGDFG
G
Y
Y
C
PCH
G
S
H
Y
D
ASGRIRKGPAPLNLEVPSYEFTSDD
M
V
I
V
G
User Run . : Multi Template Modeling Result:
(2 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120......
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MMVMKRPS
L
R
Q
F
S
W
L
LG
G
S
L
L
L
G
A
L
F
W
L
W
L
A
V
QQQE
A
T
L
A
I
R
PVGQGIGMPDG
F
S
V
W
H
HLDAN
G
I
R
F
KSITPQKD
G
L
L
I
K
FDSTAQ
G
A
A
A
K
E
V
L
G
R
ALPH
G
Y
I
I
A
L
L
EDDNS
P
T
A
W
L
S
R
L
RDAPHRLG
57
62.47
100%
-3
- C- -
M057
-
A:
[3-183]
M
M
V
M
K
R
P
S
L
R
Q
F
S
W
L
L
G
G
S
L
L
L
G
A
L
F
W
L
W
L
A
V
Q
Q
Q
E
A
T
L
A
I
R
P
V
G
Q
G
I
G
M
P
D
G
F
S
V
W
H
H
L
D
A
N
G
I
R
F
K
S
I
T
P
Q
K
D
G
L
L
I
K
F
D
S
T
A
Q
G
A
A
A
K
E
V
L
G
R
A
L
P
H
G
Y
I
I
A
L
L
E
D
D
N
S
P
T
A
W
L
S
R
L
R
D
A
P
H
R
L
G
67
56.52
100%
-22
- C- -
M067
-
A:
[9-144]
M
M
V
M
K
R
--------
L
L
G
G
S
L
L
L
G
A
L
F
W
L
W
L
A
V
Q
Q
Q
E
A
T
L
A
I
R
P
V
G
Q
G
I
G
M
P
D
G
F
S
V
W
H
H
L
D
A
N
G
I
R
F
K
S
I
T
P
Q
K
D
G
L
L
I
K
F
D
S
T
A
Q
G
A
A
A
K
E
V
L
G
R
A
L
P
H
G
Y
I
I
A
L
L
E
D
D
N
S
P
T
A
W
L
S
R
L
R
D
A
P
H
R
L
G