@TOME V2.2
(Nov 2016)
Ref.
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : T0799: (2014-05-30 )
CSFGIENTAGGSAVFHNYTRGASNSVTKNNQLLGGYGSRPWLGSTYTEHSNAALHFLGAGDTSATNHGGWIRLLVTPKGKTISDRVPAFRLSDNGDLWLVPDGAMHSDLGLVRSIETLNAAVPRFNAPSIQDGRGLKIVAPQAPEIDLIAPRGSGASAPAIRAMWCDGSLADTTRYIGATQPGSTFYIGASGHDGEKFDSMRGSVAIKSAGGWGPTSTPTQVVLETCESGSISRLPRWGVDHNGTLMPMADNRYNLGWGSGRVKQVYAVNGTINTSDARLKNDVRAMSDPETEAAKAIAKEIGFWTWKEQADMNDIREHCGLTVQRAIEIMESFGLDPFKYGFICYDKWDEHTVVSEYGPANEDGTENPIYKTIPAGDHYSFRLEELNLFIAKGFEARLSAIEDKLGM
Atome Classification :
(20 SA)
----------------------.........10........20........30..-......40........50........---60........70........---80........90--------........100.......110..-------.....120.......130.........140.......150.......160.......170....-...180..-.....-.190..------..-...200.......-210-.-..---...-..-220......-.230----------........---.---240-.---.......-250-------........-260...--------....270.......280.......290.......300.-.-.....310..--.----....320.......----330...-.-----..---.340.-......350------.......---.---360...----....370-------.---...---.....380....------...390--...---------.....400......-
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
----------------------CSFGIENTAGGS
A
V
F
HNYTRGASNSVTKNN
Q
L
L
-GGYGSRPWLGSTYTEHSN
A
A
L
H
F
LGA---GDTSATNHG
G
W
I
R
L
L
VTPKG---KTISDRV
P
A
F
R
L--------SDNG
D
L
W
L
VPDGAM
H
S
D
L
G
L
V
R
S
-------
I
E
T
L
N
AAVPRFNAPSI--QDGRG
L
K
I
VAPQAP
E
I
D
L
IAPRGSGASA
P
A
I
R
A
M
WCDGSLADT
T
R
Y
-IGAT-QPG-
S
T
F
Y
I
-GASGHD------G
E
-
K
F
D
SMRG
S
V
A
I
KS-AG--G-WG---PTS-
T
P
-
T
Q
V
V
L
E
TCE-SG------------SISRLPRW---G---VD--H---NG
T
L
MPM-AD--------NRYNLGWG-SG
R
V
K
Q
--------
V
Y
A
VN
G
T
INTS
D
A
R
L
K
N
D
V
RAMSDP
E
T
E
A
A
K
A
I
A
K
E
IG-F-WTWKEQA
D
M
N
--
D
----
I
R
E
H
CG
L
T
V
Q
R
A
I
E
----
I
M
E
SFG-L-----D
P
---
F
K
Y
G
F
-
I
C
YDKWDE-------
H
T
V
VSEY---G---PANEDG----TENP
I
---------
Y
---
K
TI---PAGDH
Y
S
F
R
L
E
E
------
L
N
L
F
-
I
--AK
G
---------
F
E
A
R
L
S
A
I
E
D
KLGM-
2
PsiBlast_PDB
86.62
25%
-61
- C2 -
3GW6
4
ENAN_BPK1F
A:
[49-274]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
I
F
-
C
G
--
G
-
E
G
---
T
S
S
-
T
T
G
A
Q
I
T
L
Y
G
A
N
-
N
T
------------
D
S
R
R
I
V
Y
N
---
G
---
D
E
--
H
L
F
Q
S
A
D
V
K
P
Y
-
N
D
--------
N
V
T
A
L
G
G
P
-
S
N
R
F
T
T
--------
A
Y
L
G
S
N
P
I
V
T
A
N
G
E
R
K
T
E
P
V
V
F
D
D
A
F
L
D
A
W
G
D
V
H
Y
I
M
Y
-
Q
-
W
L
D
A
V
Q
L
K
G
N
--
D
----
A
R
I
H
F
G
V
I
A
Q
Q
I
R
D
----
V
F
I
A
H
G
-
L
MDENS-----
C
R
Y
A
V
-
L
C
Y
D
K
Y
P
R
M
T
D
T
V
F
S
H
N
E
I
V
E
H
--------
T
D
E
E
G
N
V
T
T
T
E
E
P
V
---------
Y
---
T
E
V
V
IH
E
E
G
E
E
W
G
V
R
P
D
--------
G
I
F
-
F
--
A
E
A
A
Y
Q
R
R
K
L
E
R
I
E
A
R
L
S
A
L
E
Q
-----
10
Fugue
78.24
12%
-28
- C1 -
3C1M
6
AK_METJA
A:
[2-470]
T
T
V
M
K
F
G
GTSVGS
G
E
R
I
R
H
V
A
K
I
V
T
K
R
K
K
E
D
D
D
V
V
V
V
V
S
A
M
S
E
V
T
N
A
L
V
E
I
S
Q
Q
A
-
L
D
V
R
D
I
A
K
V
G
D
F
I
K
F
I
R
E
K
H
Y
K
A
I
E
E
A
I
K
S
E
E
I
K
E
E
V
K
K
I
I
D
S
R
I
E
E
L
E
---
K
V
L
I
G
V
A
Y
L
G
E
L
--------
T
P
K
S
R
D
Y
I
L
S
F
G
E
R
L
S
S
P
I
L
S
G
A
-------
I
R
D
L
G
E
K
S
I
A
L
--------
E
G
G
E
A
G
I
I
T
D
N
N
F
G
S
---
A
R
V
K
R
L
E
V
K
E
R
L
L
P
L
L
K
E
G
I
I
P
V
V
T
G
F
-
I
G
T
T
-
E
E
G
-
Y
I
T
T
L
-
G
R
G
G
S
D
Y
S
A
A
L
I
G
Y
-
G
L
D
A
D
I
I
E
I
W
T
D
V
-
S
G
VY
T
-
T
D
---
P
R
L
-
V
P
-
T
A
R
R
I
P
K
L
S
-
Y
I
------------
E
A
M
E
L
A
Y
F
---
G
---
A
K
VL
H
---
P
R
T
I
E
P
A
-
M
E
K
G
I
P
I
L
V
K
N
T
F
E
P
E
S
E
-
G
T
L
I
T
N
D
M
E
M
S
DSI
V
K
A
I
S
T
I
K
N
V
A
L
I
N
I
F
G
A
G
M
V
G
V
S
G
T
A
A
R
I
F
K
A
L
G
E
E
E
-
V
-
N
V
I
L
I
S
Q
G
S
S
--
E
----
T
N
I
S
L
V
V
S
E
E
D
V
D
K
A
L
K
A
L
K
R
E
F
G
-
D
-----
S
F
---
L
N
N
N
L
-
I
R
D
V
S
V
D
K
-------
D
V
C
V
I
S
V
V
G
A
G
---
M
R
G
A
K
G
----
I
A
G
K
I
---------
F
---
T
A
V
---
S
E
S
G
A
N
I
K
M
I
A
Q
GSSEV
N
I
S
F
V
-
I
D-
E
K
D
---------
L
L
N
C
V
R
K
L
H
E
K
F
I
E
K
15
HHSearch
71.96
22%
-55
- C2 -
3GW6
4
ENAN_BPK1F
A:
[85-270]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
---
L
F
--
Q
---
S
A
D
V
K
P
Y
-
N
D
--------
N
V
T
A
L
G
G
P
-
S
N
R
F
T
T
--------
A
Y
L
G
S
N
P
I
V
T
A
N
G
E
R
K
T
E
P
V
V
F
D
D
A
F
L
D
A
W
G
D
V
H
Y
I
M
Y
-
Q
-
W
L
D
A
V
Q
L
K
G
N
--
D
----
A
R
I
H
F
G
V
I
A
Q
Q
I
R
D
----
V
F
I
A
H
G
-
L
-----
M
D
ENS
C
R
Y
A
V
-
L
C
Y
D
K
Y
P
R
-------
M
T
D
T
V
F
S
---
H
N
E
I
V
E
H
T
D
E
----
E
G
N
V
T
T
T
E
E
P
V
Y
T
E
V
---
V
I
H
---
E
E
G
E
E
W
G
V
R
P
D
G
------
I
F
F
A
-
E
--
A
A
Y
---------
Q
R
R
K
L
E
R
I
E
A
R
L
S
--
8
Fugue
71.19
20%
7
- C1 -
3G3L
9
?
A:
[10-305]
-------------------------
P
A
E
A
K
Y
Y
I
A
G
T
I
T
D
A
T
T
G
--
Q
E
L
T
T
A
K
V
T
L
-
G
D
K
S
V
T
----
S
S
F
N
E
Q
V
N
-----------------
Y
K
A
E
G
Y
A
L
V
V
S
A
D
G
---
Y
Y
P
V
K
R
Q
V
Y
L
N
Q
--------
V
S
D
G
Q
----------------
T
S
-------
V
A
T
V
N
V
A
L
V
S
V
E
A
A
V
I
--
P
-----
P
V
V
P
P
T
D
P
E
T
D
I
N
E
G
E
A
T
K
V
A
D
K
A
V
E
V
A
-------
K
P
S
E
S
-
T
V
T
D
M
L
A
G
-
T
T
-----
A
T
P
E
E
------
K
K
-
A
L
D
E
T
L
------
E
M
A
G
--
G
M
K
V
---
G
E
T
-
T
P
-
E
V
L
-----
A
-
D
G
------------
S
I
L
A
I
T
P
V
---
K
---
F
T
--
N
---
P
I
Q
D
A
P
A
M
V
P
--------
Y
F
Y
N
E
G
C
E
L
T
G
D
V
K
E
--------
V
A
A
--------------
P
V
A
V
A
A
D
I
Q
K
A
F
L
S
N
A
A
K
A
L
N
M
N
-
A
G
F
V
Q
K
I
G
Y
T
--
R
----
I
S
V
L
N
G
Y
S
I
L
-----------------------------
G
Y
-
T
I
K
G
Q
L
V
S
-------
K
K
L
T
F
L
I
---
S
---------------------------------------
G
K
Y
Y
E
G
I
V
S
Y
------
Q
K
S
V
M
I
--
Y
P
N
---------
Y
Y
S
------------
5
Fugue
63.11
24%
-60
- C1 -
3GUD
1
?
A:
[3-121]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
R
H
K
T
D
I
A
P
I
S
D
K
V
L
D
A
W
E
K
V
K
F
Y
Q
Y
-
K
-
F
K
D
A
V
D
E
K
G
E
--
E
----
A
R
Y
H
F
G
V
I
A
Q
Q
I
V
K
----
V
F
E
D
E
G
-
L
-----
S
A
---
F
D
Y
G
L
-
V
G
Y
D
E
W
E
A
-------
T
-------------
E
D
E
Y
D
S
----
E
G
N
L
V
---------
E
---
K
G
R
---
E
A
G
N
I
Y
S
I
R
P
T
E
------
C
Q
W
L
-
E
--
M
A
C
---------
M
R
R
K
L
E
R
L
S
------
16
HHSearch
62.87
25%
-58
- C1 -
3GUD
1
?
A:
[3-121]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
R
H
K
T
D
I
A
P
I
S
D
K
V
L
D
A
W
E
K
V
K
F
Y
Q
Y
-
K
-
F
K
D
A
V
D
E
K
G
E
--
E
----
A
R
Y
H
F
G
V
I
A
Q
Q
I
V
K
----
V
F
E
D
E
G
-
L
-----
S
A
---
F
D
Y
G
L
-
V
G
Y
D
E
W
E
A
-------
T
E
D
-------------
E
Y
D
S
----
E
G
N
L
V
---------
E
---
K
G
R
---
E
A
G
N
I
Y
S
I
R
P
T
E
------
C
Q
W
L
-
E
--
M
A
C
---------
M
R
R
K
L
E
R
L
S
------
1
PsiBlast_PDB
57.28
29%
-55
- C1 -
3GUD
1
?
A:
[3-104]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
R
H
K
T
D
I
A
P
I
S
D
K
V
L
D
A
W
E
----
K
V
K
-
F
-
Y
Q
Y
K
F
K
D
A
V
D
--
E
KGEE
A
R
Y
H
F
G
V
I
A
Q
Q
I
V
K
----
V
F
E
D
E
G
-
L
-----
S
A
---
F
D
Y
G
L
-
V
G
Y
D
E
W
E
---------
A
T
E
D
E
Y
-----------
D
S
----
E
G
N
L
V
---------
E
---
K
G
R
---
E
A
G
N
I
Y
S
I
R
P
T
E
-----------------------------------------
14
Fugue
52.07
14%
-10
- C1 -
1G57
-
RIBB_ECOLI
A:
[5-213]
---------------------------------------------------------------------------------------------------
L
L
S
S
F
G
T
P
F
E
R
V
E
N
A
L
A
A
L
R
E
G
R
G
V
M
V
L
D
E
N
E
G
D
M
I
F
P
A
E
T
M
T
V
E
Q
M
A
L
T
I
R
H
GSGI
V
C
L
C
I
T
E
D
R
R
K
Q
L
D
L
P
M
M
--
V
E
N
N
T
S
A
Y
G
T
G
F
T
V
T
I
E
A
A
E
G
V
T
T
G
V
S
-
A
A
D
R
I
T
T
V
R
A
A
I
A
D
G
A
K
P
-
S
D
L
N
-
R
P
G
-
H
V
F
P
L
-
R
A
Q
A
G
G
------
V
L
T
R
G
G
H
T
E
A
T
I
D
L
M
T
-
L
A
--
G
-
F
K
---
P
A
G
-
V
L
-
C
E
L
T
N
D
D
G
T
-
M
A
------------
R
A
P
E
C
I
E
F
---
A
---
N
K
--
H
---
N
M
A
L
V
T
I
-
E
D
L
-------
V
A
Y
R
Q
A
H
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
34
HHSearch
45.94
14%
-43
- C1 -
3BO6
-
?
A:
[76-167]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
G
D
FA
G
----
D
K
F
H
I
S
V
Q
R
E
Q
V
P
Q
----
A
F
Q
A
L
S
G
L
LFSVD
S
P
-----------
I
D
K
W
K
V
-------
T
D
M
E
-
R
V
---
D
---
Q
Q
S
R
V
A
----
V
G
A
Q
F
---------
T
L
Y
V
K
P
D
---
Q
E
N
S
Q
Y
S
-------------
A
S
-
S
--
L
H
N
---------
T
R
Q
F
I
E
C
L
E
S
R
L
S
--
19
HHSearch
41.27
27%
-13
- C2 -
4HIZ
1
?
A:
[604-683]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
N
P
S
E
Q
R
L
I
L
C
-
G
G
--
E
-
T
P
---
Y
T
T
-
D
G
-
S
L
L
Q
L
Y
G
S
N
-
H
T
------------
Y
P
N
R
A
I
L
Y
A
PG
G
---
A
Y
--
T
---
Q
N
N
F
M
P
Y
-
L
D
--------
G
Q
V
S
L
G
G
A
-
S
N
R
W
S
E
--------
V
Y
A
S
T
G
T
I
N
T
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
HHSearch
40.31
13%
-0
- C2 -
2X3H
-
?
A:
[249-541]
-----------------------
S
Y
N
I
V
S
N
V
I
G
A
D
C
Q
H
V
T
Y
N
G
T
E
G
P
I
A
P
S
N
N
L
I
K
G
V
M
A
N
N
P
K
Y
A
A
V
V
A
G
K
G
S
T
N
L
I
S
D
V
L
---
V
D
Y
S
T
S
D
A
R
Q
A
H
G
V
T
V
E
G
S
D
---
N
V
I
N
N
V
L
M
S
G
C
D
--------
G
T
N
S
L
G
Q
R
Q
T
A
T
I
A
R
F
I
G
T
A
N
N
N
-------
Y
A
S
V
F
P
S
Y
S
A
T
G
V
I
T
F
E
S
G
S
T
R
N
F
V
E
V
K
H
P
G
R
R
N
D
L
L
S
S
A
S
T
I
D
G
A
A
T
I
D
G
T
S
N
S
N
V
V
H
A
P
A
L
G
-
Q
Y
I
G
-
S
M
S
-
G
R
F
E
W
R
I
K
S
M
S
L
------
P
S
-
G
V
L
T
S
A
D
K
Y
R
M
L
G
-
D
G
--
A
-
V
S
L
A
V
G
G
G
-
T
S
-
S
Q
V
R
L
F
T
S
D
-
G
T
S
R
T
VSLTNG
N
V
R
L
S
T
S
S
T
G
Y
---
L
---
Q
L
--
G
---
A
D
A
M
T
P
D
-
S
T
--------
G
T
Y
A
L
G
S
A
-
S
R
A
W
S
G
--------
G
F
T
Q
A
A
F
T
V
T
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
Fugue
38.05
9%
35
- C1 -
3GW4
-
?
A:
[8-199]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
Y
A
L
A
E
R
Q
A
Q
A
L
L
A
H
P
A
T
A
S
G
A
R
F
M
L
G
Y
V
-
Y
A
F
M
D
R
F
D
E
-
A
R
A
S
F
Q
------
A
L
-
Q
Q
Q
A
Q
K
S
G
D
H
T
A
E
-
H
R
--
A
-
L
H
---
Q
V
G
M
V
E
---------
R
M
A
G
------------
N
W
D
A
A
R
R
C
---
F
---
L
E
--
E
---
R
E
L
L
A
S
L
-
P
E
--------
D
P
L
A
A
S
A
N
-
A
Y
E
V
A
T
--------
V
A
L
H
F
G
D
L
A
G
A
R
Q
E
Y
E
K
S
L
V
Y
A
Q
Q
A
D
D
Q
V
A
I
A
C
A
F
R
G
L
-
G
-
D
L
A
Q
Q
E
K
N
L
L
--
E
----
A
Q
Q
H
----
W
L
R
A
R
D
----
I
F
A
E
L
E
-
D
-----
S
E
---
A
V
N
E
L
M
T
R
L
N
G
L
E
H
------------------------------------------------------------------------------------------------------------
18
HHSearch
37.07
25%
-3
* C2 *
3JU4
1
ENAN_BPK1F
A:
[591-670]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
N
P
A
G
Q
R
I
I
F
C
-
G
G
--
E
-
G
T
---
S
S
T
-
T
G
-
A
Q
I
T
L
Y
G
A
N
-
N
T
------------
D
S
R
R
I
V
Y
N
---
G
D
E
H
L
F
--
Q
---
S
A
D
V
K
P
Y
-
N
D
--------
N
V
T
A
L
G
G
P
-
S
N
R
F
T
T
--------
A
Y
L
G
S
N
P
I
V
T
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
Fugue
33.42
21%
36
- C1 -
3FXD
-
?
B:
[29-86]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
T
D
A
T
L
G
S
V
Y
S
E
I
I
S
P
V
K
D
C
I
L
T
V
A
K
A
V
S
-
F
N
P
G
G
K
D
N
T
D
A
V
--
E
----
V
L
T
E
L
N
T
K
V
E
R
A
A
L
----
N
Q
------------------------------------------------------------------------------------------------------------------------------------------
9
Fugue
30.01
12%
105
- C1 -
3T98
-
NUP54_RAT
A:
[456-494]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
Y
I
D
A
D
L
L
R
E
I
K
Q
H
L
K
Q
Q
Q
E
G
L
S
H
L
I
S
I
I
K
-
D
-
D
L
E
D
I
K
L
V
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
29.02
50%
57
- C2 -
4HIZ
-
?
A:
[654-683]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
M
P
Y
-
L
D
--------
G
Q
V
S
L
G
G
A
-
S
N
R
W
S
E
--------
V
Y
A
S
T
G
T
I
N
T
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
HHSearch
26.63
33%
76
- C1 -
1G6U
-
?
A:
[15-43]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
G
F
S
P
E
E
------
L
A
A
L
-
E
S
E
L
Q
A
---------
L
E
K
K
L
A
A
L
K
S
K
L
---
12
Fugue
24.15
16%
126
- C1 -
3PCQ
-
PSAM_THEEB
M:
[1-31]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
A
L
T
D
T
Q
V
Y
V
A
L
V
I
A
L
L
P
A
-
V
-
L
A
F
R
L
S
T
E
L
Y
--
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
23.67
28%
52
- C1 -
1EJB
1
RIB4_YEAST
A:
[28-69]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
V
I
I
D
A
L
V
-
K
G
------------
A
I
E
R
M
A
S
L
---
G
---
V
E
--
E
---
N
N
I
I
I
E
T
-
V
P
--------
G
S
Y
E
L
P
W
G
-
T
K
R
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
Fugue
23.61
26%
184
- C1 -
3R46
-
?
A:
[4-31]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
E
L
K
A
I
A
Q
E
L
K
A
I
A
K
E
L
K
-
A
-
I
A
W
E
D
K
A
I
A
Q
--
G
------------------------------------------------------------------------------------------------------------------------------------------------------------------
User Run . : Multi Template Modeling Result:
(4 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400......
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
CSFGIENTAGGS
A
V
F
HNYTRGASNSVTKNN
Q
L
L
GGYGSRPWLGSTYTEHSN
A
A
L
H
F
LGAGDTSATNHG
G
W
I
R
L
L
VTPKGKTISDRV
P
A
F
R
LSDNG
D
L
W
L
VPDGAM
H
S
D
L
G
L
V
R
S
I
E
T
L
N
AAVPRFNAPSIQDGRG
L
K
I
VAPQAP
E
I
D
L
IAPRGSGASA
P
A
I
R
A
M
WCDGSLADT
T
R
Y
IGATQPG
S
T
F
Y
I
GASGHDG
E
K
F
D
SMRG
S
V
A
I
KSAGGWGPTS
T
P
T
Q
V
V
L
E
TCESGSISRLPRWGVDHNG
T
L
MPMADNRYNLGWGSG
R
V
K
Q
V
Y
A
VN
G
T
INTS
D
A
R
L
K
N
D
V
RAMSDP
E
T
E
A
A
K
A
I
A
K
E
IGFWTWKEQA
D
M
N
D
I
R
E
H
CG
L
T
V
Q
R
A
I
E
I
M
E
SFGLD
P
F
K
Y
G
F
I
C
YDKWDE
H
T
V
VSEYGPANEDGTENP
I
Y
K
TIPAGDH
Y
S
F
R
L
E
E
L
N
L
F
I
AK
G
F
E
A
R
L
S
A
I
E
D
KLGM
55
94.77
100%
-25
- C- -
M055
-
A:
[1-480]
C
S
F
G
I
E
N
T
A
G
G
S
A
V
F
H
N
Y
T
R
G
A
S
N
S
V
T
K
N
N
Q
L
L
G
G
Y
G
S
R
P
W
L
G
S
T
Y
T
E
H
S
N
A
A
L
H
F
L
G
A
G
D
T
S
A
T
N
H
G
G
W
I
R
L
L
V
T
P
K
G
K
T
I
S
D
R
V
P
A
F
R
L
S
D
N
G
D
L
W
L
V
P
D
G
A
M
H
S
D
L
G
L
V
R
S
I
E
T
L
N
A
A
V
P
R
F
N
A
P
S
I
Q
D
G
R
G
L
K
I
V
A
P
Q
A
P
E
I
D
L
I
A
P
R
G
S
G
A
S
A
P
A
I
R
A
M
W
C
D
G
S
L
A
D
T
T
R
Y
I
G
A
T
Q
P
G
S
T
F
Y
I
G
A
S
G
H
D
G
E
K
F
D
S
M
R
G
S
V
A
I
K
S
A
G
G
W
G
P
T
S
T
P
T
Q
V
V
L
E
T
C
E
S
G
S
I
S
R
L
P
R
W
G
V
D
H
N
G
T
L
M
P
M
A
D
N
R
Y
N
L
G
W
G
S
G
R
V
K
Q
V
Y
A
V
N
G
T
I
N
T
S
D
A
R
L
K
N
D
V
R
A
M
S
D
P
E
T
E
A
A
K
A
I
A
K
E
I
G
F
W
T
W
K
E
Q
A
D
M
N
D
I
R
E
H
C
G
L
T
V
Q
R
A
I
E
I
M
E
S
F
G
L
D
P
F
K
Y
G
F
I
C
Y
D
K
W
D
E
H
T
V
V
S
E
Y
G
P
A
N
E
D
G
T
E
N
P
I
Y
K
T
I
P
A
G
D
H
Y
S
F
R
L
E
E
L
N
L
F
I
A
K
G
F
E
A
R
L
S
A
I
E
D
K
L
G
M
39
92.95
100%
-26
- C- -
M039
-
A:
[1-480]
C
S
F
G
I
E
N
T
A
G
G
S
A
V
F
H
N
Y
T
R
G
A
S
N
S
V
T
K
N
N
Q
L
L
G
G
Y
G
S
R
P
W
L
G
S
T
Y
T
E
H
S
N
A
A
L
H
F
L
G
A
G
D
T
S
A
T
N
H
G
G
W
I
R
L
L
V
T
P
K
G
K
T
I
S
D
R
V
P
A
F
R
L
S
D
N
G
D
L
W
L
V
P
D
G
A
M
H
S
D
L
G
L
V
R
S
I
E
T
L
N
A
A
V
P
R
F
N
A
P
S
I
Q
D
G
R
G
L
K
I
V
A
P
Q
A
P
E
I
D
L
I
A
P
R
G
S
G
A
S
A
P
A
I
R
A
M
W
C
D
G
S
L
A
D
T
T
R
Y
I
G
A
T
Q
P
G
S
T
F
Y
I
G
A
S
G
H
D
G
E
K
F
D
S
M
R
G
S
V
A
I
K
S
A
G
G
W
G
P
T
S
T
P
T
Q
V
V
L
E
T
C
E
S
G
S
I
S
R
L
P
R
W
G
V
D
H
N
G
T
L
M
P
M
A
D
N
R
Y
N
L
G
W
G
S
G
R
V
K
Q
V
Y
A
V
N
G
T
I
N
T
S
D
A
R
L
K
N
D
V
R
A
M
S
D
P
E
T
E
A
A
K
A
I
A
K
E
I
G
F
W
T
W
K
E
Q
A
D
M
N
D
I
R
E
H
C
G
L
T
V
Q
R
A
I
E
I
M
E
S
F
G
L
D
P
F
K
Y
G
F
I
C
Y
D
K
W
D
E
H
T
V
V
S
E
Y
G
P
A
N
E
D
G
T
E
N
P
I
Y
K
T
I
P
A
G
D
H
Y
S
F
R
L
E
E
L
N
L
F
I
A
K
G
F
E
A
R
L
S
A
I
E
D
K
L
G
M
51
91.09
100%
-26
- C- -
M051
-
A:
[1-480]
C
S
F
G
I
E
N
T
A
G
G
S
A
V
F
H
N
Y
T
R
G
A
S
N
S
V
T
K
N
N
Q
L
L
G
G
Y
G
S
R
P
W
L
G
S
T
Y
T
E
H
S
N
A
A
L
H
F
L
G
A
G
D
T
S
A
T
N
H
G
G
W
I
R
L
L
V
T
P
K
G
K
T
I
S
D
R
V
P
A
F
R
L
S
D
N
G
D
L
W
L
V
P
D
G
A
M
H
S
D
L
G
L
V
R
S
I
E
T
L
N
A
A
V
P
R
F
N
A
P
S
I
Q
D
G
R
G
L
K
I
V
A
P
Q
A
P
E
I
D
L
I
A
P
R
G
S
G
A
S
A
P
A
I
R
A
M
W
C
D
G
S
L
A
D
T
T
R
Y
I
G
A
T
Q
P
G
S
T
F
Y
I
G
A
S
G
H
D
G
E
K
F
D
S
M
R
G
S
V
A
I
K
S
A
G
G
W
G
P
T
S
T
P
T
Q
V
V
L
E
T
C
E
S
G
S
I
S
R
L
P
R
W
G
V
D
H
N
G
T
L
M
P
M
A
D
N
R
Y
N
L
G
W
G
S
G
R
V
K
Q
V
Y
A
V
N
G
T
I
N
T
S
D
A
R
L
K
N
D
V
R
A
M
S
D
P
E
T
E
A
A
K
A
I
A
K
E
I
G
F
W
T
W
K
E
Q
A
D
M
N
D
I
R
E
H
C
G
L
T
V
Q
R
A
I
E
I
M
E
S
F
G
L
D
P
F
K
Y
G
F
I
C
Y
D
K
W
D
E
H
T
V
V
S
E
Y
G
P
A
N
E
D
G
T
E
N
P
I
Y
K
T
I
P
A
G
D
H
Y
S
F
R
L
E
E
L
N
L
F
I
A
K
G
F
E
A
R
L
S
A
I
E
D
K
L
G
M
57
90.97
100%
-26
- C- -
M057
-
A:
[1-480]
C
S
F
G
I
E
N
T
A
G
G
S
A
V
F
H
N
Y
T
R
G
A
S
N
S
V
T
K
N
N
Q
L
L
G
G
Y
G
S
R
P
W
L
G
S
T
Y
T
E
H
S
N
A
A
L
H
F
L
G
A
G
D
T
S
A
T
N
H
G
G
W
I
R
L
L
V
T
P
K
G
K
T
I
S
D
R
V
P
A
F
R
L
S
D
N
G
D
L
W
L
V
P
D
G
A
M
H
S
D
L
G
L
V
R
S
I
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L
N
A
A
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P
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F
N
A
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D
G
R
G
L
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I
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A
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A
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G
A
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A
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A
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A
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A
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A
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A
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C
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M
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V
Y
A
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N
G
T
I
N
T
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D
A
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L
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N
D
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A
M
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D
P
E
T
E
A
A
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A
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A
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I
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F
W
T
W
K
E
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A
D
M
N
D
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C
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A
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E
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N
L
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A
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L
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M