@TOME V2.2
(Nov 2016)
Ref.
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : CTL4_HUMAN: (2015-12-07 )
MGGKQRDEDDEAYGKPVKYDPSFRGPIKNRSCTDVICCVLFLLFILGYIVVGIVAWLYGDPRQVLYPRNSTGAYCGMGENKDKPYLLYFNIFSCILSSNIISVAENGLQCPTPQVCVSSCPEDPWTVGKNEFSQTVGEVFYTKNRNFCLPGVPWNMTVITSLQQELCPSFLLPSAPALGRCFPWTNVTPPALPGITNDTTIQQGISGLIDSLNARDISVKIFEDFAQSWYWILVALGVALVLSLLFILLLRLVAGPLVLVLILGVLGVLAYGIYYCWEEYRVLRDKGASISQLGFTTNLSAYQSVQETWLAALIVLAVLEAILLLMLIFLRQRIRIAIALLKEASKAVGQMMSTMFYPLVTFVLLLICIAYWAMTALYLATSGQPQYVLWASNISSPGCEKVPINTSCNPTAHLVNSSCPGLMCVFQGYSSKGLIQRSVFNLQIYGVLGLFWTLNWVLALGQCVLAGAFASFYWAFHKPQDIPTFPLISAFIRTLRYHTGSLAFGALILTLVQIARVILEYIDHKLRGVQNPVARCIMCCFKCCLWCLEKFIKFLNRNAYIMIAIYGKNFCVSAKNAFMLLMRNIVRVVVLDKVTDLLLFFGKLLVVGGVGVLSFFFFSGRIPGLGKDFKSPHLNYYWLPIMTSILGAYVIASGFFSVFGMCVDTLFLCFLEDLERNNGSLDRPYYMSKSLLKILGKKNEAPPDNKKRKK
Atome Classification :
(20 SA)
---.....-----------....10--........20.......--.30........40........50.....--...60........70........---80.--..----------------.....90..----------------------......100.-......110---.........120-..-.......-130.......-------.140..----..---...150--------------.........160.....--------..170--.......180------.......----190.........200.......210----------........220........230------.----........-------240.......250..--.....260.--------......270-----..-------...-----..280......-.290.......300...--------....310.......320.......330.......---340.......-------------------350....----..--------.360--------.......-------370---------.....---...380.------......390...-...---.400..-....-------.410.---..-....420------------......---...430..------....-----.440--.........450.......460...---....470..------------.....480.......490.......-------------..500...-....510-----......------.520.-----------......530.......540..------.....550..-------...-----..560.......570.......580...-------....590.......600--------.....-------..610----------........620-........630.......640......---.650-.......660.......670....-...680.......690.......700.......710------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
---MGGKQ-----------RDED
D
E
--AYGKPVKYDPSFRGPIK--NR
S
C
T
D
V
I
C
C
V
L
F
L
L
F
I
L
G
Y
I
V
V
G
I
V
A
W
--LYGDPR
Q
V
LYPRNSTGAYCGMGE---NKD--K
P
----------------
Y
L
L
Y
F
N
I
F
S
----------------------
C
I
L
S
S
N
I
I
S
V
-
A
ENGLQC-----P
T
P
Q
V
C
V
S
SC---PE-DPWTV
G
K
-
N
-
E
F
S
Q
T
V
G
E
-------
V
F
Y
TKN----R
N
---
F
CLP----------------GVPW
N
M
T
V
I
T
S
L
Q
Q
E
L
C
--------
P
S
FLL--PSAPALGRCF------PWTNVTP----P--ALPGITN
D
T
T
I
Q
Q
G
I
S
G
L
I
D
S-----------LNAR
D
I
S
V
K
-
I
F
E
D
F
A
Q
S
W
Y
--------
W
----
I
L
V
A
L
G
V
A
-------
L
V
L
S
L
L
F
I
L
L
L
R
LVA--
G
P
L
V
L
V
L
I
L
--------
G
V
L
G
V
L
A
Y
G
-----
I
Y
-------
Y
C
W
-----
E
E
Y
R
V
L
R
DKGA-SISQLGFTT
N
L
S
A
Y
Q
S
V
--------
Q
E
T
W
L
A
A
L
I
V
L
A
V
L
E
A
I
L
L
L
M
L
I
F
L
R
Q
R
I
R
I
A
I
A
---
L
L
K
E
A
S
K
A
V
G
-------------------
Q
M
M
S
T
M
F
----
Y
P
--------
L
V
T
F
--------
V
L
L
L
I
C
I
-------
A
Y
----------
W
A
M
T
A
---
L
Y
LATSG------QP
Q
Y
V
L
W
ASNIS-SPG---CEKVPI-NTSC-------NP
T
A
H
---
L
V-NSSCP--------------
G
L
M
C
V
F---QGYSSKG
L
------
I
Q
R
S
-----
V
F
----
N
L
Q
I
Y
G
V
L
G
L
F
W
T
L
N
W
V
L
A
L
G
Q
C
V
L
---
A
G
A
F
A
S
F
Y
W
------------AFHKPQDIP
T
F
P
L
I
S
A
--
F
I
R
T
L
R
Y-------------HTG
S
L
A
F
G
-
A
L
I
L
T
L
V
-----
Q
I
A
R
V
I
------
L
E
Y
I
D
-----------
H
K
L
RG
V
Q
N
P
V
A
R
C
I
M
C
C
F
K
C
C
------
L
W
C
L
E
K
F
I
K
F
-------LNR-----N
A
Y
I
M
I
A
I
YGK
N
F
C
V
S
A
K
N
A
F
M
L
L
M
R
N
I
-------
V
R
V
V
V
L
D
K
V
T
D
L
L
L
F
F
G
--------
K
L
L
V
V-------G
G
V
G
-----------
V
L
S
F
F
F
FSGR--IPGLGKDFKSPHL
N
Y
Y
W
L
P
I
M
T
S
I
L
G
A
---
Y
V
I
A
-
S
G
F
F
S
V
F
G
M
C
V
D
T
L
F
L
C
F
L
E
D
L
E
R-NNGSLDR
P
Y
Y
M
S
K
S
L
L
K
I
LGKKNEAPPDNKKRKK--------
22
Fugue
89.95
17%
-122
- C5 -
4WZ9
3
?
A:
[40-926]
------
Q
A
-----------
V
D
E
R
Y
R
LP
T
T
S
I
P
I
H
Y
D
L
H
L
R
T
E
I
H
RN
E
R
T
F
T
G
T
V
G
I
Q
L
Q
V
V
Q
A
T
D
K
L
V
M
H
N
R
G
L
--
V
M
S
S
A
K
V
S
S
L
P
N
G
V
T
G
A
P
T
L
I
G
D
V
Q
Y
S
T
D
--
T
T
FE
H
I
T
F
T
S
P
T
I
L
Q
P
G
T
Y
L
L
E
V
A
F
Q
G
R
L
A
TNDDGF
Y
V
S
S
Y
V
A
DNG
E
R
R
Y
L
A
T
T
Q
F
E
S
T
S
A
R
M
A
F
P
C
YDEPG
L
K
A
T
F
T
V
S
I
T
---
H
S
-
L
S
Y
K
A
I
S
-
N
-
M
P
Q
K
T
T
T
D
I
ET
D
M
R
T
T
F
F
E
K
T
----
P
A
M
S
T
Y
L
L
A
----------------
F
V
V
S
D
F
Q
L
R
L
S
G
A
Q
R
V
Y
V
RPNAFNE
A
T
F
A
L
--
E
A
G
V
K
I
L
K
V
L
D
D
H
L
GI
P
Y
D
T
Y
M
P
K
L
D
Q
I
--
A
I
P
D
F
A
A
G
A
M
E
N
W
G
L
V
T
Y
R
E
Q
ALLFNPAVST
Y
R
G
K
T
N
V
A
T
T
-
I
A
H
E
Y
A
H
Q
W
F
GNLVSPEW
W
----
E
Y
I
W
L
N
E
G
-------
F
A
T
L
Y
E
F
Y
A
L
D
M
A
Y
P
--
G
Q
E
Y
W
E
L
F
N
--------
Q
Q
V
I
Q
Y
A
M
G
-----
Q
D
G
QASTRP
M
N
W
N
A
A
T
P
G
E
I
S
A
L
F
D
R
V
A
-
Y
-
D
K
S
G
S
V
L
N
M
M
R
H
V
L
G
--------
D
D
N
W
K
A
G
L
K
A
Y
L
T
D
R
A
L
Q
G
A
V
D
E
Q
L
Y
A
G
L
Q
S
A
I
E
GKG
V
L
P
N
-
G
V
T
V
A
-------------------
Q
I
M
R
T
W
T
N
E
A
G
Y
P
--------
V
L
N
V
R
R
SYDT
G
D
V
I
I
S
Q
E
R
-------
F
Y
ND
R
K
V
P
N
TNI
W
M
I
P
Y
---
N
Y
V
H
Q
A
K
------
A
D
F
N
E
F
--
D
D
F
Q
-
W
L
A
---
T
K
A
A
R
I
-
E
T
T
V
-------
P
A
N
E
W
---
I
V
F
N
K
Q
Q
V
--------------
G
Y
Y
R
V
N
---
Y
D
E
H
N
W
E
L
------
I
T
N
A
-----
L
H
E
NWA
S
I
H
R
L
N
R
A
Q
L
I
D
D
A
Y
W
L
A
R
S
G
R
L
D
L
---
R
V
A
L
R
F
M
T
Y
------------
L
R
N
E
R
E
Y
A
P
W
T
A
A
N
V
A
--
L
T
Y
F
N
N
R
-------------
L
R
G
T
A
E
Y
H
-
N
F
L
I
F
V
D
-----
A
L
I
E
D
I
------
Y
S
L
L
T
IDAVSPDDT
L
L
H
K
Y
L
V
Q
T
I
S
T
W
A
C
S
M
G
Y
T
D
C
L
------
M
K
T
A
A
L
L
K
A
E
-------
A
S
G
TGPAV
H
P
D
I
A
S
V
T
Y
C
Y
G
M
R
S
A
L
E
S
E
F
Q
Y
L
Y
R
K
M
-------
M
N
S
K
N
L
A
E
R
T
M
L
I
D
S
L
G
C
SNN
K
E
F
L
K
A
F
L
T
-------
T
A
L
G
SINYR
A
D
E
R
R
R
V
V
Q
A
I
Y
S
G
G
R
T
G
V
D
A
L
I
E
F
L
M
D
P
A
L
V
N
E
F
V
S
T
L
S
----
T
---
S
T
L
N
-
S
A
L
S
A
I
A
S
R
T
N
N
V
E
E
M
N
K
L
N
A
L
I
T
-
A
L
G
--
S
R
V
N
S
Q
T
A
A
N
L
R
T
T
A
Q
A
N
L
D
W
V
N
G
F
E
G
L
M
L
S
N
F
L
AEA
18
Fugue
80.88
16%
-128
- C5 -
4CR2
-
RPN1_YEAST
Z:
[49-993]
LEL
L
V
E
R
L
-----------
K
E
D
D
S
S
--
L
Y
E
A
S
L
N
---
A
L
K
E
S
I
K
--
N
S
T
S
S
-------------------------
M
T
A
V
P
K
P
L
K
F
L
R
P
T
Y
P
D
L
C
S
I
Y
D
---
K
W
T
--
D
P
----------------
N
L
K
--
S
S
L
A
----------------------
D
V
L
S
I
L
A
M
T
Y
-
S
E
N
G
K
H
D
-----
S
L
R
Y
R
L
L
S
D
V
---
S
D
F
E
G
W
G
H
E
Y
I
R
-
H
L
A
L
E
I
G
E
-------
V
Y
N
D
Q
V
----
E
K
---
D
A
E
D
ETSSDGSKSDGSAATS
G
F
E
F
S
K
E
D
T
L
R
L
C
L
D
I
V
--------
P
Y
F
L
K
H
N
G
E
E
D
A
V
D
L
L
L
------
E
I
E
S
I
------
D
--
K
L
P
Q
F
V
D
E
N
T
F
Q
R
V
C
Q
Y
M
V
A
C
-----------
V
P
L
L
P
P
P
E
D
V
A
F
L
K
T
A
Y
S
I
Y
--------
L
S
Q
NE
L
T
D
A
I
A
L
A
V
RLGE
E
D
M
I
R
S
V
F
D
A
T
S
D
P
V
M
H
--
K
Q
L
A
Y
I
L
A
A
Q
KTSFEYE
G
V
Q
D
I
I
G
N
G
KLSEH
F
L
-------
Y
L
A
-----
K
E
L
N
L
T
---
G
P
-
K
V
P
E
D
I
Y
K
S
H
L
D
N
S
K
S
V
F
S
S
A
GLDS
A
Q
Q
N
L
A
S
S
F
V
N
G
F
L
N
L
G
Y
C
N
D
K
L
I
V
D
N
D
N
W
V
Y
K
T
---
K
G
D
G
M
T
S
A
V
A
-------------------
S
I
G
S
I
Y
Q
----
W
N
--------
L
D
G
L
--------
Q
Q
L
D
K
Y
L
Y
VDE
P
E
V
K
A
----------
G
A
L
L
G
---
I
G
I
S
A
S
G
VHDGEV
E
P
A
L
L
L
L
Q
D
Y
V
T
-
N
P
D
T
K
I
S
S
A
A
I
L
-
G
L
G
I
A
F
AGSKN
D
E
V
L
G
---
L
L
-
L
P
I
A
A
STDLPIETAAM
A
S
L
A
L
A
H
V
F
---
V
G
T
C
N
G
D
I
------
T
T
S
I
-----
M
D
----
N
F
L
E
R
T
A
I
E
L
K
T
D
W
V
R
F
L
A
L
A
L
G
I
L
Y
MG
Q
G
E
Q
V
D
D
V
L
------------
E
T
I
S
A
I
E
H
P
M
T
S
A
I
E
V
--
L
V
G
S
C
A
Y
TGTGD
V
L
L
I
Q
D
L
L
H
R
L
T
L
A
Y
A
-
V
L
G
I
A
L
I
A
L
GE
D
I
G
K
E
M
S
------
L
R
H
F
G
-----------
H
L
M
H
Y
G
N
E
H
I
R
R
M
V
P
L
A
M
G
I
V
S
VSDPQ
M
K
V
F
D
T
L
T
R
F
S
H
DAD
L
E
V
S
M
-----
N
S
I
F
A
M
G
L
C
G
---
A
G
T
N
N
A
R
L
A
Q
L
L
R
Q
L
A
S
Y
YSRE
Q
D
A
L
F
I
T
R
L
A
Q
G
L
L
H
L
G
--------
K
G
T
M
T
MDVFNDA
H
V
L
N
-----------
K
V
T
L
A
S
I
L
T
T
--
A
V
G
L
V
S
P
S
F
M
L
K
H
H
Q
L
F
Y
M
L
N
A
G
I
R
P
K
---
F
I
L
A
L
N
D
E
G
E
P
I
K
V
N
V
R
V
G
Q
P
V
L
L
N
H
G
E
R
A
E
L
E
T
D
E
Y
I
S
Y
T
S
H
I
E
G
V
V
I
L
K
K
N
---
P
D
Y
R
E
E
E
---------
19
Fugue
71.62
14%
-122
- C5 -
3KX2
1
PRP43_YEAST
A:
[1-755]
---
M
G
S
K
R
R
F
S
SEHPDPVE
T
S
I
P
E
Q
--
A
A
E
I
A
E
E
L
S
K
Q
H
P
L
P
S
E
--
E
P
L
V
H
H
D
A
--
G
E
F
K
G
L
Q
R
H
H
T
S
A
E
E
A
Q
K
--
L
E
D
G
K
I
N
P
F
T
G
R
E
F
T
P
K
Y
V
D
I
L
K
---
I
R
R
E
L
P
V
----------------
H
A
Q
R
D
E
F
L
K
----------------------
L
Y
Q
N
N
Q
I
M
V
F
V
G
E
T
G
S
----------------------------
G
K
-
T
T
Q
I
P
Q
F
V
L
F
-------
D
E
M
P
H
L
----
E
N
---
T
Q
V
A
----------------
C
T
Q
P
R
R
V
A
A
M
S
V
A
Q
R
V
A
--------
E
E
M
D
V
--
K
L
G
E
E
V
G
Y
S
I
------
R
F
E
N
K
T
S
----
N
KT
I
L
K
Y
M
T
D
G
M
L
L
R
E
A
M
E
----
D
-----------
H
D
L
S
R
Y
S
C
I
-
I
L
D
E
A
H
E
R
----------------------
T
-------
L
A
T
D
I
L
M
G
L
L
K
Q
V
V
K
R
R
P
D
L
K
I
I
I
M
S
--------
A
T
L
D
A
E
K
F
Q
-----
R
Y
---------
F
-----
N
D
A
P
L
L
A
V
P
G
R
-
T
Y
P
V
E
L
Y
Y
T
P
E
F
Q
R
D
Y
L
--------
D
S
A
I
R
T
V
L
Q
I
H
A
T
E
E
A
G
D
I
L
L
F
L
T
G
E
D
E
I
E
D
A
V
R
---
K
I
S
L
E
G
D
Q
L
V
R
E
EGC
G
P
L
S
V
Y
P
L
Y
GSLP
P
H
Q
Q
Q
R
I
F
----
E
P
APESHNG
R
P
G
R
K
--------
V
V
I
S
T
N
I
-------
A
E
----------
T
S
L
T
I
D
GI
V
Y
V
V
D
P
G
------
F
S
K
Q
K
V
Y
N
P
R
I
R
-
V
E
S
---
L
L
V
S
P
I
S
K
A
S
A
-------
Q
Q
R
A
G
---
R
A
-
G
R
T
R
P
--------------
G
K
C
F
R
L
YT
E
E
A
F
Q
K
E
L
I
EQSYPE
I
L
R
S
NL
S
S
T
V
L
----
E
L
K
K
L
G
I
D
D
L
V
-
H
F
D
F
M
D
P
P
A
P
E
T
M
---
M
R
A
L
E
E
L
N
Y
L
ACLDDEGNLT
P
L
G
R
L
A
S
Q
F
P
L
D
P
M
L
A
V
--
M
L
I
G
S
F
E
-------------
F
Q
C
S
Q
E
I
--
L
T
I
V
A
M
L
-----
S
V
P
N
V
F
I
R
P
TKD
K
K
R
A
D
-----------
D
A
K
N
I
F
A
H
P
D
G
D
H
I
T
L
L
N
V
Y
H
------
A
F
K
S
D
E
A
Y
E
Y
--------
G
I
-----
H
K
W
C
R
D
H
Y
L
N
Y
R
S
L
S
A
A
D
N
I
R
S
Q
L
E
R
L
M
-------
N
R
Y
N
-
L
E
L
N
T
T
D
Y
E
S
P
K
--------
Y
F
D
N
I
-------
R
K
A
L
-----------
A
S
G
F
F
M
Q
V
A
K
--
K
R
S
G
A
K
G
Y
I
T
V
K
D
N
Q
D
V
L
I
H
P
S
T
V
L
G
H
DAE
W
V
I
Y
-
N
E
F
V
L
T
S
K
N
Y
I
R
T
V
T
S
V
R
P
E
W
L
I
E
I
A
P
A
Y
Y
D
L
S
N
F
Q
K
G
D
V
K
L
S
L
E
R
I
K
E
K
V
D
R
L
N
E
L
K
Q
--------
17
Fugue
63.03
15%
-82
- C5 -
3OC2
-
?
A:
[35-545]
---------------------------
A
R
S
V
R
H
I
A
I
P
A
H
R
G
L
I
T
--
D
R
N
G
E
-------------
P
L
A
V
S
T
P
V
T
T
--
L
W
A
N
P
K
E
L
M
T
A
K
E
R
W
P
Q
L
A
A
A
L
G
---
Q
D
T
--
K
L
----------------
F
A
D
R
I
E
--------------------------------------------------------
Q
N
---
A
E
-
R
E
F
I
Y
L
V
-
R
-
G
L
T
P
E
Q
G
E
-------
G
V
I
A
L
K
-----------
V
P
----------------
G
V
Y
S
I
E
E
F
R
R
F
Y
--------------------
P
A
G
E
V
V
A
H
A
V
------
G
F
T
D
V
D
D
----
R
--
G
R
E
G
I
E
L
A
---------
F
D
E
W
-----------
L
A
G
V
P
G
K
R
Q
-
V
L
K
D
---------------------------------------------------------------------------------------------------
R
R
G
R
V
I
K
D
V
Q
V
T
K
N
A
K
P
G
K
T
L
A
L
S
I
D
L
R
L
--------
Q
Y
L
A
H
R
E
L
R
N
A
L
L
E
N
G
A
K
A
G
S
L
V
I
M
D
V
K
T
G
E
I
L
A
---
M
T
N
Q
P
T
Y
N
P
N
-------------------
N
R
R
N
L
Q
P
----
A
A
--------
M
R
N
R
--------
A
M
I
D
V
F
E
-------
P
G
----------
S
T
V
K
P
---
F
S
M
S
A
A
L
------
A
S
G
R
W
K
P
S
D
I
V
D
V
Y
P
G
---
T
L
Q
I
G
R
-
Y
T
I
R
-------
D
V
S
R
N
---
S
R
-
Q
L
D
L
T
--------------
G
I
L
I
-------
K
S
S
N
V
G
------
I
S
K
I
-----
A
F
----
D
I
G
A
E
S
I
Y
S
V
M
Q
Q
V
G
L
-------------
G
Q
D
T
G
L
G
F
------------
P
G
E
R
V
G
N
L
P
N
H
R
K
W
P
--------
K
A
-------------
E
T
A
T
L
A
Y
G
Y
G
L
S
V
T
A
I
-----
Q
L
A
H
A
Y
------
A
A
L
A
N
-----------
D
---
G
K
S
V
P
L
S
-------------------------
M
-------
T
R
V
-----
D
R
V
----------------------
P
D
G
-------
V
Q
V
I
S
P
E
V
A
S
T
V
Q
G
M
L
Q
--------
Q
V
V
E
A
-------
Q
G
G
V
-----------------
F
R
A
Q
--
V
P
G
Y
H
A
A
G
K
S
G
T
A
R
K
A
Y
R
S
L
F
A
G
F
A
P
A
-------------------
T
D
P
R
I
A
M
V
V
V
I
D
E
-
P
F
G
G
L
V
S
A
P
V
F
S
K
V
M
A
G
A
L
R
L
M
N
-
V
P
P
D
N
L
------------
4
PsiBlast_PDB
37.90
30%
-67
- C6 -
1GT8
4
DPYD_PIG
A:
[109-177]
--------------------------------------------------------------------------------------------------------------------------------
Y
Y
G
A
A
K
----------------------
M
I
F
S
D
N
P
L
G
L
-
T
-
C
G
M
V
C
-----
P
T
S
D
L
C
V
G
G
C
NLY
A
T
-
E
E
G
S
I
N
I
-
G
-
G
L
Q
Q
F
A
S
E
-------
V
F
K
A
M
N
I
P
Q
I
R
N
---
P
C
L
P
----------------
S
Q
E
K
M
P
E
A
Y
S
A
K
I
A
L
L
G
--------
A
G
P
A
S
--
I
S
C
A
S
F
L
A
R
L
------
G
Y
S
D
I
T
I
----
F
--
E
K
Q
E
Y
V
G
G
L
S
T
S
E
I
P
Q
F
R
L
P
Y
-----------
D
V
V
N
F
E
I
E
L
-
M
K
D
L
G
V
K
I
I
C
--------
G
----
K
S
L
S
E
N
E
I
-------
T
L
N
T
L
K
E
E
G
Y
K
A
A
F
I
--
G
I
G
L
P
E
P
K
T
--------
D
D
I
F
Q
G
L
T
Q
-----
D
Q
-------
G
F
Y
-----
T
S
K
D
F
L
P
L
V
A
K
-
S
S
K
A
G
M
C
A
C
H
S
P
L
P
S
I
R
--------
G
A
V
I
V
L
G
A
G
D
T
A
F
D
C
A
T
S
A
L
R
C
G
A
R
R
V
F
L
V
F
R
K
G
---
F
V
N
I
R
A
V
P
E
E
-------------------
V
E
L
A
K
E
E
----
K
C
--------
E
F
L
P
--------
F
L
S
P
R
K
V
-------
I
V
----------
K
G
G
R
I
---
V
A
V
Q
F
V
R
------
T
E
Q
D
E
T
G
K
W
N
E
D
-
E
D
Q
---
I
V
H
L
K
A
-
D
V
V
I
-------
S
A
F
G
S
---
V
L
-
R
D
P
K
V
--------------
K
E
A
L
S
P
---
I
K
F
N
R
W
D
L
------
P
E
V
D
-----
P
E
----
T
M
Q
T
S
E
P
W
V
F
A
G
G
D
I
V
G
M
A
N
T
T
V
E
S
---
V
N
D
G
K
Q
A
S
W
------------
Y
I
H
K
Y
I
Q
A
Q
Y
G
A
S
V
S
A
--
K
P
E
L
P
L
F
-------------
Y
T
P
V
D
L
V
D
-
I
S
V
E
M
A
G
-----
L
K
F
I
N
P
------
F
G
L
A
S
-----------
A
A
P
T
T
S
S
S
M
I
R
R
A
F
E
A
G
W
G
F
A
------
L
T
K
T
F
S
L
D
K
D
-------
I
V
T
-----
N
V
S
P
R
I
V
R
G
T
T
S
G
P
M
Y
G
P
G
Q
S
S
F
L
N
I
E
L
-------
I
S
E
K
T
A
A
Y
W
C
Q
S
V
T
E
L
K
--------
A
D
F
P
D
-------
N
I
V
I
-----------
A
S
I
M
C
S
Y
N
K
N
--
D
W
M
E
L
S
R
K
A
E
A
S
G
A
D
A
L
E
L
N
L
S
C
P
H
G
M
---
G
E
M
G
-
L
A
C
G
Q
D
P
E
L
V
R
N
I
C
R
W
V
R
Q
A
V
Q
I
P
-
F
F
A
K
L
T
P
N
V
T
D
I
V
S
I
A
R
A
A
K
E
G
G
A
D
G
V
T
A
T
N
T
V
S
--------
3
PsiBlast_PDB
37.52
30%
-74
- C6 -
1H7W
3
DPYD_PIG
A:
[109-177]
--------------------------------------------------------------------------------------------------------------------------------
Y
Y
G
A
A
K
----------------------
M
I
F
S
D
N
P
L
G
L
-
T
-
C
G
M
V
C
-----
P
T
S
D
L
C
V
G
G
C
NLY
A
T
-
E
E
G
S
I
N
I
-
G
-
G
L
Q
Q
F
A
S
E
-------
V
F
K
A
M
N
I
P
Q
I
R
N
---
P
C
L
P
----------------
S
Q
E
K
M
P
E
A
Y
S
A
K
I
A
L
L
G
--------
A
G
P
A
S
--
I
S
C
A
S
F
L
A
R
L
------
G
Y
S
D
I
T
I
----
F
--
E
K
Q
E
Y
V
G
G
L
S
T
S
E
I
P
Q
F
R
L
P
Y
-----------
D
V
V
N
F
E
I
E
L
-
M
K
D
L
G
V
K
I
I
C
--------
G
----
K
S
L
S
E
N
E
I
-------
T
L
N
T
L
K
E
E
G
Y
K
A
A
F
I
--
G
I
G
L
P
E
P
K
T
--------
D
D
I
F
Q
G
L
T
Q
-----
D
Q
-------
G
F
Y
-----
T
S
K
D
F
L
P
L
V
A
K
-
S
S
K
A
G
M
C
A
C
H
S
P
L
P
S
I
R
--------
G
A
V
I
V
L
G
A
G
D
T
A
F
D
C
A
T
S
A
L
R
C
G
A
R
R
V
F
L
V
F
R
K
G
---
F
V
N
I
R
A
V
P
E
E
-------------------
V
E
L
A
K
E
E
----
K
C
--------
E
F
L
P
--------
F
L
S
P
R
K
V
-------
I
V
----------
K
G
G
R
I
---
V
A
V
Q
F
V
R
------
T
E
Q
D
E
T
G
K
W
N
E
D
-
E
D
Q
---
I
V
H
L
K
A
-
D
V
V
I
-------
S
A
F
G
S
---
V
L
-
R
D
P
K
V
--------------
K
E
A
L
S
P
---
I
K
F
N
R
W
D
L
------
P
E
V
D
-----
P
E
----
T
M
Q
T
S
E
P
W
V
F
A
G
G
D
I
V
G
M
A
N
T
T
V
E
S
---
V
N
D
G
K
Q
A
S
W
------------
Y
I
H
K
Y
I
Q
A
Q
Y
G
A
S
V
S
A
--
K
P
E
L
P
L
F
-------------
Y
T
P
V
D
L
V
D
-
I
S
V
E
M
A
G
-----
L
K
F
I
N
P
------
F
G
L
A
S
-----------
A
A
P
T
T
S
S
S
M
I
R
R
A
F
E
A
G
W
G
F
A
------
L
T
K
T
F
S
L
D
K
D
-------
I
V
T
-----
N
V
S
P
R
I
V
R
G
T
T
S
G
P
M
Y
G
P
G
Q
S
S
F
L
N
I
E
L
-------
I
S
E
K
T
A
A
Y
W
C
Q
S
V
T
E
L
K
--------
A
D
F
P
D
-------
N
I
V
I
-----------
A
S
I
M
C
S
Y
N
K
N
--
D
W
M
E
L
S
R
K
A
E
A
S
G
A
D
A
L
E
L
N
L
S
C
P
H
G
M
---
G
E
R
G
-
M
G
L
A
C
G
Q
D
P
E
L
V
R
N
I
C
R
W
V
R
Q
A
V
Q
-
I
P
F
F
A
K
L
T
P
N
V
T
D
I
V
S
I
A
R
A
A
K
E
G
G
A
D
G
V
T
A
T
N
T
--------
7
PsiBlast_PDB
37.40
30%
-72
- C6 -
1H7X
3
DPYD_PIG
A:
[109-177]
--------------------------------------------------------------------------------------------------------------------------------
Y
Y
G
A
A
K
----------------------
M
I
F
S
D
N
P
L
G
L
-
T
-
C
G
M
V
C
-----
P
T
S
D
L
C
V
G
G
C
NLY
A
T
-
E
E
G
S
I
N
I
-
G
-
G
L
Q
Q
F
A
S
E
-------
V
F
K
A
M
N
I
P
Q
I
R
N
---
P
C
L
P
----------------
S
Q
E
K
M
P
E
A
Y
S
A
K
I
A
L
L
G
--------
A
G
P
A
S
--
I
S
C
A
S
F
L
A
R
L
------
G
Y
S
D
I
T
I
----
F
--
E
K
Q
E
Y
V
G
G
L
S
T
S
E
I
P
Q
F
R
L
P
Y
-----------
D
V
V
N
F
E
I
E
L
-
M
K
D
L
G
V
K
I
I
C
--------
G
----
K
S
L
S
E
N
E
I
-------
T
L
N
T
L
K
E
E
G
Y
K
A
A
F
I
--
G
I
G
L
P
E
P
K
T
--------
D
D
I
F
Q
G
L
T
Q
-----
D
Q
-------
G
F
Y
-----
T
S
K
D
F
L
P
L
V
A
K
-
S
S
K
A
G
M
C
A
C
H
S
P
L
P
S
I
R
--------
G
A
V
I
V
L
G
A
G
D
T
A
F
D
C
A
T
S
A
L
R
C
G
A
R
R
V
F
L
V
F
R
K
G
---
F
V
N
I
R
A
V
P
E
E
-------------------
V
E
L
A
K
E
E
----
K
C
--------
E
F
L
P
--------
F
L
S
P
R
K
V
-------
I
V
----------
K
G
G
R
I
---
V
A
V
Q
F
V
R
------
T
E
Q
D
E
T
G
K
W
N
E
D
-
E
D
Q
---
I
V
H
L
K
A
-
D
V
V
I
-------
S
A
F
G
S
---
V
L
-
R
D
P
K
V
--------------
K
E
A
L
S
P
---
I
K
F
N
R
W
D
L
------
P
E
V
D
-----
P
E
----
T
M
Q
T
S
E
P
W
V
F
A
G
G
D
I
V
G
M
A
N
T
T
V
E
S
---
V
N
D
G
K
Q
A
S
W
------------
Y
I
H
K
Y
I
Q
A
Q
Y
G
A
S
V
S
A
--
K
P
E
L
P
L
F
-------------
Y
T
P
V
D
L
V
D
-
I
S
V
E
M
A
G
-----
L
K
F
I
N
P
------
F
G
L
A
S
-----------
A
A
P
T
T
S
S
S
M
I
R
R
A
F
E
A
G
W
G
F
A
------
L
T
K
T
F
S
L
D
K
D
-------
I
V
T
-----
N
V
S
P
R
I
V
R
G
T
T
S
G
P
M
Y
G
P
G
Q
S
S
F
L
N
I
E
L
-------
I
S
E
K
T
A
A
Y
W
C
Q
S
V
T
E
L
K
--------
A
D
F
P
D
-------
N
I
V
I
-----------
A
S
I
M
C
S
Y
N
K
N
--
D
W
M
E
L
S
R
K
A
E
A
S
G
A
D
A
L
E
L
N
L
S
A
P
H
G
M
---
G
E
R
G
-
M
G
L
A
C
G
Q
D
P
E
L
V
R
N
I
C
R
W
V
R
Q
A
V
Q
-
I
P
F
F
A
K
L
T
P
N
V
T
D
I
V
S
I
A
R
A
A
K
E
G
G
A
D
G
V
T
A
T
N
T
--------
5
PsiBlast_PDB
36.84
30%
-73
- C6 -
1GTE
3
DPYD_PIG
A:
[109-177]
--------------------------------------------------------------------------------------------------------------------------------
Y
Y
G
A
A
K
----------------------
M
I
F
S
D
N
P
L
G
L
-
T
-
C
G
M
V
C
-----
P
T
S
D
L
C
V
G
G
C
NLY
A
T
-
E
E
G
S
I
N
I
-
G
-
G
L
Q
Q
F
A
S
E
-------
V
F
K
A
M
N
I
P
Q
I
R
N
---
P
C
L
P
----------------
S
Q
E
K
M
P
E
A
Y
S
A
K
I
A
L
L
G
--------
A
G
P
A
S
--
I
S
C
A
S
F
L
A
R
L
------
G
Y
S
D
I
T
I
----
F
--
E
K
Q
E
Y
V
G
G
L
S
T
S
E
I
P
Q
F
R
L
P
Y
-----------
D
V
V
N
F
E
I
E
L
-
M
K
D
L
G
V
K
I
I
C
--------
G
----
K
S
L
S
E
N
E
I
-------
T
L
N
T
L
K
E
E
G
Y
K
A
A
F
I
--
G
I
G
L
P
E
P
K
T
--------
D
D
I
F
Q
G
L
T
Q
-----
D
Q
-------
G
F
Y
-----
T
S
K
D
F
L
P
L
V
A
K
-
S
S
K
A
G
M
C
A
C
H
S
P
L
P
S
I
R
--------
G
A
V
I
V
L
G
A
G
D
T
A
F
D
C
A
T
S
A
L
R
C
G
A
R
R
V
F
L
V
F
R
K
G
---
F
V
N
I
R
A
V
P
E
E
-------------------
V
E
L
A
K
E
E
----
K
C
--------
E
F
L
P
--------
F
L
S
P
R
K
V
-------
I
V
----------
K
G
G
R
I
---
V
A
V
Q
F
V
R
------
T
E
Q
D
E
T
G
K
W
N
E
D
-
E
D
Q
---
I
V
H
L
K
A
-
D
V
V
I
-------
S
A
F
G
S
---
V
L
-
R
D
P
K
V
--------------
K
E
A
L
S
P
---
I
K
F
N
R
W
D
L
------
P
E
V
D
-----
P
E
----
T
M
Q
T
S
E
P
W
V
F
A
G
G
D
I
V
G
M
A
N
T
T
V
E
S
---
V
N
D
G
K
Q
A
S
W
------------
Y
I
H
K
Y
I
Q
A
Q
Y
G
A
S
V
S
A
--
K
P
E
L
P
L
F
-------------
Y
T
P
V
D
L
V
D
-
I
S
V
E
M
A
G
-----
L
K
F
I
N
P
------
F
G
L
A
S
-----------
A
A
P
T
T
S
S
S
M
I
R
R
A
F
E
A
G
W
G
F
A
------
L
T
K
T
F
S
L
D
K
D
-------
I
V
T
-----
N
V
S
P
R
I
V
R
G
T
T
S
G
P
M
Y
G
P
G
Q
S
S
F
L
N
I
E
L
-------
I
S
E
K
T
A
A
Y
W
C
Q
S
V
T
E
L
K
--------
A
D
F
P
D
-------
N
I
V
I
-----------
A
S
I
M
C
S
Y
N
K
N
--
D
W
M
E
L
S
R
K
A
E
A
S
G
A
D
A
L
E
L
N
L
S
C
P
H
G
M
---
G
L
A
C
-
G
Q
D
P
E
L
V
R
N
I
C
R
W
V
R
Q
A
V
Q
I
P
F
F
A
-
K
L
T
P
N
V
T
D
I
V
S
I
A
R
A
A
K
E
G
G
A
D
G
V
T
A
T
N
T
V
S
G
L
M
--------
6
PsiBlast_PDB
36.60
30%
-69
- C6 -
1GTH
4
DPYD_PIG
A:
[109-177]
--------------------------------------------------------------------------------------------------------------------------------
Y
Y
G
A
A
K
----------------------
M
I
F
S
D
N
P
L
G
L
-
T
-
C
G
M
V
C
-----
P
T
S
D
L
C
V
G
G
C
NLY
A
T
-
E
E
G
S
I
N
I
-
G
-
G
L
Q
Q
F
A
S
E
-------
V
F
K
A
M
N
I
P
Q
I
R
N
---
P
C
L
P
----------------
S
Q
E
K
M
P
E
A
Y
S
A
K
I
A
L
L
G
--------
A
G
P
A
S
--
I
S
C
A
S
F
L
A
R
L
------
G
Y
S
D
I
T
I
----
F
--
E
K
Q
E
Y
V
G
G
L
S
T
S
E
I
P
Q
F
R
L
P
Y
-----------
D
V
V
N
F
E
I
E
L
-
M
K
D
L
G
V
K
I
I
C
--------
G
----
K
S
L
S
E
N
E
I
-------
T
L
N
T
L
K
E
E
G
Y
K
A
A
F
I
--
G
I
G
L
P
E
P
K
T
--------
D
D
I
F
Q
G
L
T
Q
-----
D
Q
-------
G
F
Y
-----
T
S
K
D
F
L
P
L
V
A
K
-
S
S
K
A
G
M
C
A
C
H
S
P
L
P
S
I
R
--------
G
A
V
I
V
L
G
A
G
D
T
A
F
D
C
A
T
S
A
L
R
C
G
A
R
R
V
F
L
V
F
R
K
G
---
F
V
N
I
R
A
V
P
E
E
-------------------
V
E
L
A
K
E
E
----
K
C
--------
E
F
L
P
--------
F
L
S
P
R
K
V
-------
I
V
----------
K
G
G
R
I
---
V
A
V
Q
F
V
R
------
T
E
Q
D
E
T
G
K
W
N
E
D
-
E
D
Q
---
I
V
H
L
K
A
-
D
V
V
I
-------
S
A
F
G
S
---
V
L
-
R
D
P
K
V
--------------
K
E
A
L
S
P
---
I
K
F
N
R
W
D
L
------
P
E
V
D
-----
P
E
----
T
M
Q
T
S
E
P
W
V
F
A
G
G
D
I
V
G
M
A
N
T
T
V
E
S
---
V
N
D
G
K
Q
A
S
W
------------
Y
I
H
K
Y
I
Q
A
Q
Y
G
A
S
V
S
A
--
K
P
E
L
P
L
F
-------------
Y
T
P
V
D
L
V
D
-
I
S
V
E
M
A
G
-----
L
K
F
I
N
P
------
F
G
L
A
S
-----------
A
A
P
T
T
S
S
S
M
I
R
R
A
F
E
A
G
W
G
F
A
------
L
T
K
T
F
S
L
D
K
D
-------
I
V
T
-----
N
V
S
P
R
I
V
R
G
T
T
S
G
P
M
Y
G
P
G
Q
S
S
F
L
N
I
E
L
-------
I
S
E
K
T
A
A
Y
W
C
Q
S
V
T
E
L
K
--------
A
D
F
P
D
-------
N
I
V
I
-----------
A
S
I
M
C
S
Y
N
K
N
--
D
W
M
E
L
S
R
K
A
E
A
S
G
A
D
A
L
E
L
N
L
S
C
P
H
G
M
---
G
E
R
G
-
M
G
L
A
C
G
Q
D
P
E
L
V
R
N
I
C
R
W
V
R
Q
A
V
Q
-
I
P
F
F
A
K
L
T
P
N
V
T
D
I
V
S
I
A
R
A
A
K
E
G
G
A
D
G
V
T
A
T
N
T
--------
23
Fugue
35.11
14%
454
- C5 -
4PVZ
-
?
C:
[3-37]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
-
G
S
T
N
K
R
K
R
E
Q
I
S
T
D
N
E
A
K
M
Q
I
Q
E
E
K
S
P
K
K
K
R
K
K
R
--------
12
HHSearch
34.28
31%
55
- C6 -
3BK7
2
?
A:
[68-83]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
C
-----
T
G
C
G
I
C
V
H
K
C
---
P
F
-
N
A
I
S
I
V
N
-
L
-
P
E
Q
L
D
E
D
C
-------
V
H
R
Y
G
V
----
N
A
---
F
V
L
Y
----------------
R
L
P
I
V
K
D
G
M
V
V
G
I
V
G
P
N
--------
G
T
G
K
T
--
T
A
V
K
I
L
A
G
Q
L
------
I
P
N
L
C
E
D
----
N
--
D
S
W
D
N
V
I
R
A
F
R
G
N
E
L
Q
N
Y
F
E
R
-----------
L
K
N
G
E
I
R
P
V
-
V
K
P
Q
Y
V
D
L
L
P
--------
K
----
A
V
K
G
K
V
R
E
-------
L
L
K
K
V
D
E
V
G
K
F
E
E
V
V
--
K
E
L
E
L
E
N
V
L
--------
D
R
E
L
H
Q
L
S
G
-----
G
E
-------
L
Q
R
-----
V
A
I
A
A
A
L
L
R
K
A
-
H
F
Y
F
F
D
E
P
S
S
Y
L
D
I
R
Q
R
--------
L
K
V
A
R
V
I
R
R
L
A
N
E
G
K
A
V
L
V
V
E
H
D
L
A
V
L
D
Y
L
S
D
V
I
---
H
V
V
Y
G
E
P
G
V
Y
-------------------
G
I
F
S
K
P
K
----
G
T
--------
R
N
G
I
--------
N
E
F
L
Q
G
Y
-------
L
K
----------
D
E
N
V
R
---
F
R
P
Y
E
I
R
------
F
T
K
L
S
E
R
V
D
V
E
R
-
E
T
L
---
V
E
Y
P
R
L
-
V
K
D
Y
-------
G
S
F
K
L
---
E
V
-
E
P
G
E
I
--------------
R
K
G
E
V
I
---
G
I
V
G
P
N
G
I
------
G
K
T
T
-----
F
V
----
K
M
L
A
G
V
E
E
P
T
E
G
K
V
E
W
D
L
T
V
A
Y
K
P
Q
---
Y
I
K
A
E
Y
E
G
T
------------
V
Y
E
L
L
S
K
I
D
S
S
K
L
N
S
N
--
F
Y
K
T
E
L
L
-------------
K
P
L
G
I
I
D
L
-
Y
D
R
N
V
E
D
-----
L
S
G
G
E
L
------
Q
R
V
A
I
-----------
A
A
T
L
L
R
D
A
D
I
Y
L
L
D
E
P
S
A
Y
L
D
------
V
E
Q
R
L
A
V
S
R
A
-------
I
R
H
-----
L
M
E
K
N
E
K
T
A
L
V
V
E
H
D
V
L
M
I
D
Y
V
S
D
R
L
I
V
-------
F
E
G
E
P
G
R
H
G
R
A
L
P
P
M
G
M
--------
R
E
G
M
N
-------
R
F
L
A
-----------
S
V
G
I
T
F
R
R
D
P
--
D
S
G
R
P
R
A
N
K
E
G
S
V
K
D
R
E
Q
K
A
R
G
E
Y
Y
Y
A
---------------------------------------------------------------------------
2
PsiBlast_PDB
32.89
36%
152
- C7 -
3N94
-
A:
[398-446]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
D
S
-
S
P
G
---
C
P
G
M
W
D
-
N
I
T
C
-------
W
K
P
A
H
VG
E
M
V
-
L
V
S
C
P
--------------
E
L
F
R
I
F
---
N
P
D
Q
D
M
G
V
------
V
S
R
N
-----
C
T
----
E
D
G
W
S
E
P
F
P
H
Y
F
D
A
C
G
F
D
E
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
32.04
35%
167
* C7 *
2JOD
-
PACR_HUMAN
A:
[44-96]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
M
G
F
N
D
S
-
S
P
G
---
C
P
G
M
W
D
-
N
I
T
C
-------
W
K
P
A
H
VG
E
M
V
-
L
V
S
C
P
--------------
E
L
F
R
I
F
---
N
P
D
Q
D
M
G
V
------
V
S
R
N
-----
C
T
----
E
D
G
W
S
E
P
F
P
H
Y
F
D
A
C
G
F
D
E
Y
E
S
E
T
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
HHSearch
30.93
15%
217
- C6 -
2K21
-
KCNE1_HUMAN
A:
[44-85]
--------------------------------------------------------
A
L
Y
V
L
M
V
L
G
F
F
G
F
F
T
L
G
I
M
L
S
Y
I
R
S
K
K
L
E
H
S
N
D
P
F
N
V
Y
I
E
S
D
A
---
W
Q
E
--
K
D
----------------
K
A
Y
V
Q
A
R
V
L
----------------------
E
S
Y
K
S
C
Y
V
V
E
-
N
H
L
A
I
E
Q
-----
P
N
T
H
L
P
E
T
K
P
---
S
P
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
Fugue
29.99
20%
343
* C6 *
3MRA
-
?
?:
[277-301]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
M
L
F
T
M
I
F
V
I
S
S
I
I
I
T
V
V
---
V
I
N
T
H
H
R
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
Fugue
29.77
31%
303
* C5 *
1LYP
-
?
?:
[1-32]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
L
R
K
R
L
R
K
F
R
N
---
K
I
K
E
K
L
K
K
I
G
-------------------
Q
K
I
Q
G
L
L
----
P
K
--------
L
A
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
HHSearch
26.43
40%
2294
- C1 -
1SOP
1
?
A:
[8-17]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
Q
C
V
P
T
C
---
P
Q
-
Y
C
C
P
A
K
R
-
K
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26
Fugue
26.23
30%
896
- C4 -
4J2L
1
CIC_HUMAN
C:
[1-25]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
F
V
W
------------
T
N
V
E
P
R
S
V
A
V
F
P
W
H
S
L
V
P
F
L
A
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
HHSearch
23.22
29%
599
- C6 -
2KVO
-
PSB28_SYNY3
A:
[91-111]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
R
F
M
R
F
-------
M
E
R
-----
Y
G
A
----
E
N
G
L
G
F
S
K
S
E
L
E
H
H
H
H
H
H
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
HHSearch
19.62
29%
1411
- C2 -
3WU2
-
PSBI_THEVL
I:
[20-31]
--------------------------------------------------------------------
L
F
V
F
G
F
--
L
S
G
D
P
A
R
N
P
K
R
K
D
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------