@TOME V2.2
(Nov 2016)
Ref.
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : LAT4_HUMAN: (2015-12-08 )
MAPTLATAHRRRWWMACTAVLENLLFSAVLLGWGSLLIMLKSEGFYSYLCTEPENVTNGTVGGTAEPGHEEVSWMNGWLSCQAQDEMLNLAFTVGSFLLSAITLPLGIVMDKYGPRKLRLLGSACFAVSCLLIAYGASKPNALSVLIFIALALNGFGGMCMTFTSLTLPNMFGDLRSTFIALMIGSYASSAVTFPGIKLIYDAGVSFIVVLVVWAGCSGLVFLNCFFNWPLEPFPGPEDMDYSVKIKFSWLGFDHKITGKQFYKQVTTVGRRLSVGSSMRSAKEQVALQEGHKLCLSTVDLEVKCQPDAAVAPSFMHSVFSPILLLSLVTMCVTQLRLIFYMGAMNNILKFLVSGDQKTVGLYTSIFGVLQLLCLLTAPVIGYIMDWRLKECEDASEEPEEKDANQGEKKKKKRDRQIQKITNAMRAFAFTNLLLVGFGVTCLIPNLPLQILSFILHTIVRGFIHSAVGGLYAAVYPSTQFGSLTGLQSLISALFALLQQPLFLAMMGPLQGDPLWVNVGLLLLSLLGFCLPLYLICYRRQLERQLQQRQEDDKLFLKINGSSNQEAFV
Atome Classification :
(20 SA)
.........10........20-........30........40........50........60........70........80........90........100.......110.......120---.......130.......140.......150.......160-.----......170..-.....180-.......190.......200.-......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430..-.-....440..---.----....450.......460.......470.......480.......490.......500.......510.......520.......530.......540.......550.......560.......
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MAPT
L
A
T
A
H
R
R
R
W
W
M
A
C
T
A
V
L
-
E
N
L
L
F
S
A
V
L
L
G
W
G
S
L
L
I
M
L
KSEG
F
Y
S
Y
LCTEPENVTNGTVGGTAEPGH
E
E
V
S
W
M
N
G
W
LSCQA
Q
D
E
M
L
N
L
A
F
T
V
G
S
F
L
L
S
A
I
T
L
P
L
G
I
V
MDKYGP
R
K
L
R
L
L
G
---
S
A
C
F
A
V
S
C
L
L
I
AYGASKP
N
A
L
S
V
L
I
F
I
A
L
A
L
NGFGG
M
C
M
T
-
F
----TSL
T
L
P
N
M
F
G
D
-
L
R
S
T
F
I
A
L
-
M
I
G
SYASSAVTFP
G
I
K
L
I
YDA-
G
V
S
F
I
V
V
L
V
V
W
AGCS
G
L
V
F
L
N
C
F
FNWPLEPFPGPEDM
D
Y
S
V
K
I
K
F
S
W
LGFDHKI
T
G
K
Q
F
Y
K
Q
V
T
T
VGRRLSV
G
S
S
M
R
S
A
K
E
Q
V
A
L
Q
EG
H
K
L
C
L
S
T
V
D
L
E
V
K
CQPDAAV
A
P
S
F
M
H
S
V
F
S
P
I
L
L
L
S
L
V
T
M
C
V
T
Q
L
R
L
I
F
Y
M
G
A
M
N
N
I
L
K
F
L
VSGDQ
K
T
V
G
L
Y
T
S
I
F
G
V
L
Q
L
L
C
L
L
T
A
P
V
I
G
Y
I
M
DW
R
L
K
E
CEDASEEPEEKDANQ
G
E
K
K
K
K
K
R
D
R
Q
I
Q
K
I
T
N
A
M
R
A
F
A
F
T
N
L
L
-
L
-
V
GF
G
V
T
CLI---P----NL
P
L
Q
I
L
S
F
I
L
H
T
I
V
R
G
F
I
H
S
A
V
G
G
L
Y
A
A
VYPSTQFG
S
L
T
G
L
Q
S
L
I
S
A
L
F
A
L
L
QQ
P
L
F
L
A
M
MGPLQGD
P
L
W
V
N
V
G
L
L
L
L
S
L
L
G
F
C
L
P
L
Y
L
I
C
Y
R
R
Q
L
E
R
Q
L
Q
Q
RQED
D
K
L
F
L
K
INGSSNQEAFV
21
Fugue
77.39
10%
-103
- C1 -
1PV6
-
LACY_ECOLI
A:
[1-417]
----
M
Y
Y
L
K
N
T
N
F
W
M
F
G
L
F
F
F
-
F
Y
F
F
I
M
G
A
Y
F
P
F
F
P
I
W
L
H
D
I
N
H
---------------------------------------
I
S
K
S
D
T
G
I
I
F
A
A
I
S
L
F
S
L
L
F
Q
P
L
F
G
L
L
S
D
K
L
G
L
R
K
Y
L
L
W
I
---
I
T
G
M
L
V
M
F
A
P
F
F
I
F
I
F
G
P
L
L
Q
Y
N
I
L
V
G
S
I
V
G
G
----------------
I
Y
L
G
F
C
F
N
A
-
G
A
P
A
V
E
A
F
-
I
E
K
V
S
R
R
S
N
F
E
F
G
R
A
R
M
F
G
C
V
-
G
W
A
L
G
A
S
I
V
G
I
M
F
T
I
N
------------------
N
Q
F
V
F
W
L
G
S
G
C
A
L
I
L
A
V
L
L
F
F
A
K
T
D
A
P
S
S
A
T
V
A
N
A
V
G
A
N
H
S
A
F
S
L
K
L
A
L
E
L
F
R
------------------------------
Q
P
K
L
W
F
L
S
L
Y
V
I
G
V
S
C
T
Y
D
V
F
D
Q
Q
F
A
N
F
F
T
S
F
F
A
T
G
E
Q
G
T
R
V
F
G
Y
V
T
T
M
G
E
L
L
N
A
S
I
M
F
F
A
P
L
I
I
N
R
I
-------------------------
G
G
K
N
A
L
L
L
A
G
T
I
M
S
V
R
I
I
G
S
S
-
F
-
A
-----------
T
----
S
A
L
E
V
V
I
L
K
T
L
H
M
F
E
V
P
F
L
L
V
G
C
F
K
Y
I
T
S
Q
F
E
V
R
F
S
A
T
I
Y
L
V
C
F
C
F
F
K
Q
L
A
M
I
F
M
S
V
L
A
G
N
M
Y
E
S
I
G
F
Q
G
A
Y
L
V
L
G
L
V
A
L
G
F
T
L
I
S
V
F
T
L
S
G
P
G
P
L
S
L
L
R
R
Q
V
N
E
V
A
-----------------
3
HHSearch
67.14
18%
-131
- C2 -
1PW4
-
GLPT_ECOLI
A:
[19-210]
---
I
D
P
T
Y
R
R
L
R
W
Q
I
F
L
G
I
F
F
-
G
Y
A
A
Y
Y
L
V
R
K
N
F
A
L
A
M
P
Y
L
V
E
---------------------------------
Q
G
F
S
-----
R
G
D
L
G
F
A
L
S
G
I
S
I
A
Y
G
F
S
K
F
I
M
G
S
V
S
D
R
S
N
P
R
V
F
L
P
A
G
---
L
I
L
A
A
A
V
M
L
F
M
G
F
V
P
W
A
T
-
S
S
I
A
V
M
F
V
L
L
F
L
C
G
W
F
Q
G
M
G
W
P
P
----
C
G
R
T
M
V
H
W
W
S
Q
K
E
R
G
G
I
V
S
V
-
W
N
C
A
H
N
V
G
G
G
I
P
P
L
L
F
L
L
G
M
A
W
F
N
D
W
H
A
A
L
Y
M
P
A
F
C
A
I
L
V
A
L
F
A
F
A
M
M
R
D
T
P
Q
S
C
G
L
P
P
I
E
E
Y
K
N
D
T
A
K
Q
I
F
M
Q
Y
V
L
P
N
K
L
L
W
Y
I
A
I
A
N
V
F
V
Y
L
L
R
Y
G
I
L
D
W
S
P
T
Y
L
K
E
V
K
H
F
A
L
D
K
S
S
W
A
Y
F
L
Y
E
Y
A
G
I
P
G
T
L
L
C
G
W
M
S
D
K
V
F
R
G
N
R
G
A
T
G
V
F
F
M
T
L
V
T
I
A
T
I
V
Y
W
M
N
P
A
G
N
P
T
V
D
M
I
C
M
I
V
I
G
F
L
I
Y
G
P
V
M
L
I
G
L
H
A
L
E
L
A
P
K
K
A
A
G
T
A
A
G
F
T
G
L
F
G
Y
L
G
G
S
V
A
A
S
A
I
V
G
Y
T
V
D
F
F
G
W
D
G
G
F
M
V
M
I
G
G
S
I
L
-
A
-
V
I
L
L
I
V
V
M
I
---
G
----
E
K
R
R
H
E
Q
L
L
Q
E
L
V
P
--------------------------------------------------------------------------------------------------------------
8
HHSearch
61.74
13%
-129
- C2 -
2CFQ
-
LACY_ECOLI
A:
[259-394]
--------------------------------------------------------------------------------------
R
V
F
G
Y
V
T
T
M
G
E
L
L
N
A
S
I
M
F
F
A
P
L
I
I
N
R
I
G
G
K
N
A
L
L
L
A
---
G
T
I
M
S
V
R
I
I
G
S
S
F
A
T
S
-----
A
L
E
V
V
I
L
K
T
L
H
M
F
E
V
P
F
L
L
V
G
----
C
F
K
Y
I
T
S
Q
F
E
V
R
F
S
A
T
I
Y
L
V
C
F
C
F
F
K
Q
L
A
M
I
F
M
S
V
L
A
G
N
M
Y
E
-
S
I
G
F
Q
G
A
Y
L
V
L
G
L
V
A
L
G
F
T
L
I
S
V
F
T
L
S
G
P
G
P
L
S
L
L
R
R
Q
V
N
E
V
A
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
HHSearch
57.93
14%
-149
- C2 -
3O7Q
1
FUCP_ECOLI
A:
[22-176]
----------
R
S
Y
I
I
P
F
A
L
L
C
S
L
F
F
L
W
A
V
A
N
N
L
N
D
I
L
L
P
Q
F
Q
Q
A
--------------------------------
F
T
L
T
-----
N
F
Q
A
G
L
I
Q
S
A
F
Y
F
G
Y
F
I
I
P
I
P
A
G
I
L
M
K
K
L
S
Y
K
A
G
I
I
T
G
---
L
F
L
Y
A
L
G
A
A
L
F
W
P
A
A
E
I
--
M
N
Y
T
L
F
L
V
G
L
F
I
I
A
A
G
L
G
C
L
E
T
A
----
A
N
P
F
V
T
V
L
G
P
E
S
S
G
H
F
R
L
N
L
-
A
Q
T
F
N
S
F
G
A
I
I
A
V
V
F
G
Q
S
L
I
L
-
S
N
V
P
H
Q
S
Q
D
V
L
D
K
M
S
P
E
Q
L
S
A
Y
K
H
S
L
V
L
S
V
Q
T
P
Y
M
I
I
V
A
I
V
L
L
V
A
L
L
I
M
L
T
K
F
P
A
L
Q
S
D
N
H
S
D
A
K
Q
G
S
F
S
A
S
L
S
R
L
A
R
I
R
H
W
R
W
A
V
L
A
Q
F
C
Y
V
G
A
Q
T
A
C
W
S
Y
L
I
R
Y
A
V
E
E
I
P
G
M
T
A
G
F
A
A
N
Y
L
T
G
T
M
V
C
F
F
I
G
R
F
T
G
T
W
L
I
S
R
F
A
P
H
K
V
L
A
A
Y
A
L
I
A
M
A
L
C
L
I
S
A
F
A
G
G
H
V
G
L
I
A
L
T
L
C
S
A
F
M
S
I
Q
Y
P
T
I
F
S
L
G
I
K
N
L
G
Q
D
T
K
Y
G
S
S
F
I
V
M
T
I
I
G
G
G
I
V
T
P
V
M
G
F
V
S
D
A
A
G
-
N
-
I
P
T
A
E
L
I
P
A
---
L
----
C
F
A
V
I
F
I
F
A
R
F
R
S
Q
T
-------------------------------------------------------------------------------------------------------------
4
HHSearch
52.05
17%
-154
- C2 -
3WDO
-
?
A:
[45-186]
-------------------------------------------------------------------------------------
E
A
L
I
G
I
A
I
G
I
Y
G
L
T
Q
A
V
F
Q
I
P
F
G
L
L
S
D
R
I
G
R
K
P
L
I
V
G
G
---
L
A
V
F
A
A
G
S
V
I
A
A
L
S
D
S
-----
I
W
G
I
I
L
G
R
A
L
Q
G
S
G
A
I
-
A
A
-
A
----
V
M
A
L
L
S
D
L
T
R
E
Q
N
R
T
K
A
M
A
F
-
I
G
V
S
F
G
I
T
F
A
I
A
M
V
L
G
P
I
I
T
H
-
K
L
G
L
H
A
L
F
W
M
I
A
I
L
A
T
T
G
I
A
L
T
I
W
V
V
P
N
S
S
T
H
V
L
N
R
E
S
G
M
V
K
G
S
F
S
K
V
L
A
E
P
R
L
L
K
L
N
F
G
I
M
C
L
H
M
L
L
M
S
T
F
V
A
L
P
G
Q
L
A
D
A
G
F
P
A
A
E
H
W
K
V
Y
L
A
T
M
L
I
A
F
G
S
V
V
P
F
I
I
Y
A
E
V
K
R
K
M
K
Q
V
F
V
F
C
V
G
L
I
V
V
A
E
I
V
L
W
N
A
Q
T
Q
F
W
Q
L
V
V
G
V
Q
L
F
F
V
A
F
N
L
M
E
A
L
L
P
S
L
I
S
K
E
S
P
A
G
Y
K
G
T
A
M
G
V
Y
S
T
S
Q
F
L
G
V
A
I
G
G
S
L
G
G
W
I
D
G
M
F
D
G
Q
G
V
F
L
A
G
A
M
L
A
A
V
W
L
A
V
A
S
T
M
K
E
P
-
P
-
Y
V
S
S
L
R
I
E
I
---
P
----
A
D
I
A
A
N
E
A
L
K
V
R
L
L
E
T
E
G
V
K
E
V
L
I
A
E
E
E
H
S
A
Y
V
K
I
D
S
K
V
T
N
R
F
E
V
E
Q
A
I
R
Q
A
L
-----------------------------------------------------------------------
6
HHSearch
47.23
14%
-121
- C2 -
2GFP
-
EMRD_ECOLI
A:
[38-174]
----------------------------------------------------------------------------
L
N
V
R
-----
E
G
A
V
Q
S
V
M
G
A
Y
L
L
T
Y
G
V
S
Q
L
F
Y
G
P
I
S
D
R
V
G
R
R
P
V
I
L
V
G
---
M
S
I
F
M
L
A
T
L
V
A
V
T
T
S
S
-----
L
T
V
L
I
A
A
S
A
M
Q
G
M
G
T
G
V
G
G
V
M
----
A
R
T
L
P
R
D
L
Y
E
R
T
Q
L
R
H
A
N
S
L
-
L
N
M
G
I
L
V
S
P
L
L
A
P
L
I
G
G
L
L
D
T
-
M
W
N
W
R
A
C
Y
L
F
L
L
V
L
C
A
G
V
T
F
S
M
A
R
W
M
P
E
T
R
P
V
D
A
P
R
T
R
L
L
T
S
Y
K
T
L
F
G
N
S
G
F
N
C
Y
L
L
M
L
I
G
G
L
A
G
I
A
A
F
E
A
C
S
G
V
L
M
G
A
V
L
G
L
S
S
M
T
V
S
I
L
F
I
L
P
I
P
A
A
F
F
G
A
W
F
A
G
R
P
N
K
R
F
S
T
L
M
W
Q
S
V
I
C
C
L
L
A
G
L
L
M
W
I
P
D
W
F
G
V
M
N
V
W
T
L
L
V
P
A
A
L
F
F
F
G
A
G
M
L
F
P
L
A
T
S
G
A
M
E
P
F
P
F
L
A
G
T
A
G
A
L
V
G
G
L
Q
N
I
G
S
G
V
L
A
S
L
S
A
M
L
P
Q
T
G
Q
G
S
L
G
L
L
M
T
L
M
G
L
L
I
V
L
C
W
L
P
L
-----------------------------------------------------------------------------------------------------------------------------------------------------
7
HHSearch
42.17
13%
-135
- C2 -
2CFQ
-
LACY_ECOLI
A:
[42-181]
-------------------------------------------------------------------------------------
K
S
D
T
G
I
I
F
A
A
I
S
L
F
S
L
L
F
Q
P
L
F
G
L
L
S
D
K
L
G
L
R
K
Y
L
L
W
I
I
T
G
M
L
V
M
F
A
P
F
F
I
F
I
F
G
P
L
L
----
Q
Y
N
I
L
V
G
S
I
V
G
G
I
Y
L
G
F
C
F
N
A
G
A
P
A
V
E
A
F
I
E
K
V
S
R
--
R
S
N
F
E
F
G
R
-
A
R
M
F
G
C
V
G
W
A
L
G
A
S
I
V
G
I
M
F
T
--
I
N
N
Q
F
V
F
W
L
G
S
G
C
A
L
I
L
A
V
L
L
F
F
A
K
T
D
A
P
S
S
A
T
V
A
N
A
V
G
A
N
H
S
A
F
S
L
K
L
A
L
E
L
F
R
Q
P
K
L
W
F
L
S
L
Y
V
I
G
V
S
C
T
Y
D
V
F
D
Q
Q
F
A
N
F
F
T
S
F
F
A
T
G
E
Q
G
T
R
V
F
G
Y
V
T
T
M
G
E
L
L
N
A
S
I
M
F
F
A
P
L
I
I
N
R
I
G
G
K
N
A
L
L
L
A
G
T
I
M
S
V
R
I
I
G
S
S
F
A
T
S
A
L
E
V
V
I
L
K
T
L
H
M
F
E
V
P
F
L
L
V
G
C
F
K
Y
I
T
S
Q
F
E
V
R
F
S
A
T
I
Y
L
V
C
F
C
F
F
K
Q
L
A
M
I
F
M
S
V
L
A
G
N
M
Y
E
S
I
G
F
Q
G
A
Y
L
V
L
G
L
V
A
L
G
F
T
-
L
-
I
S
V
F
T
L
S
G
P
---
G
----
P
L
S
L
L
R
R
Q
V
N
E
V
A
---------------------------------------------------------------------------------------------------------------
10
HHSearch
41.06
14%
-131
- C2 -
3WDO
-
?
A:
[50-160]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
A
I
G
I
Y
G
L
T
Q
A
V
F
Q
I
P
F
G
L
L
S
D
R
I
G
R
K
P
L
----------------------------------
I
V
G
G
L
A
V
-
F
A
A
G
S
V
I
A
A
L
S
---
D
----
S
I
W
G
I
I
L
G
R
A
L
Q
G
S
G
--
A
I
A
A
A
V
M
A
L
L
S
D
L
T
R
E
Q
N
R
T
K
A
M
A
F
I
G
V
S
F
G
I
T
F
A
I
A
M
V
L
G
P
I
I
T
H
K
L
G
L
H
A
L
F
W
M
I
A
I
L
A
T
T
G
I
A
L
T
I
W
V
V
P
N
S
S
T
H
V
L
N
R
E
S
G
M
V
K
G
S
F
S
K
V
L
A
E
P
R
L
L
K
L
N
F
G
I
11
HHSearch
38.88
11%
-110
- C2 -
3O7Q
1
FUCP_ECOLI
A:
[65-177]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
I
Q
S
A
F
Y
F
G
Y
F
I
I
P
I
P
A
G
I
L
M
K
K
L
S
Y
K
A
G
----------------------------------
I
I
T
G
L
F
L
Y
A
-
L
G
A
A
L
F
W
P
A
A
E
I
M
----
N
Y
T
L
F
L
V
G
L
F
I
I
A
A
G
L
G
C
L
E
T
A
A
N
P
F
V
T
V
L
G
P
E
S
S
G
H
F
R
L
N
L
A
Q
T
F
N
S
F
G
A
I
I
A
V
V
F
G
Q
S
L
I
L
S
N
V
P
H
Q
S
Q
D
V
L
D
K
M
S
P
E
Q
L
S
A
Y
K
H
S
L
V
L
S
V
Q
T
P
Y
M
I
I
V
A
I
V
L
L
V
A
L
L
I
M
L
T
K
F
P
A
L
Q
S
D
N
H
20
Fugue
38.37
6%
403
- C2 -
1A93
2
B:
[1-32]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
C
G
G
M
R
R
K
N
D
T
H
Q
Q
D
I
D
D
L
K
R
Q
N
A
L
L
E
Q
Q
V
R
A
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------
16
Fugue
37.97
14%
371
- C2 -
2RMY
-
BIN1_HUMAN
A:
[1-34]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
A
E
M
G
S
K
G
V
T
A
G
K
I
A
S
N
V
Q
K
K
L
T
R
A
Q
E
K
V
L
Q
K
L
Y
------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
37.28
26%
107
- C2 -
2E1D
-
TALDO_MOUSE
A:
[182-231]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
I
S
P
F
V
G
R
I
L
D
W
H
V
A
N
T
D
K
K
S
Y
E
P
------
Q
G
D
P
G
V
K
----
S
V
T
K
I
Y
N
Y
Y
K
K
F
G
Y
K
T
I
V
-
M
-
G
A
S
F
R
N
T
G
E
---
I
----
K
A
L
A
G
C
D
F
L
T
I
S
P
K
L
L
G
E
L
L
K
D
N
S
K
L
A
P
A
L
S
V
K
A
A
Q
T
S
D
S
E
K
I
H
L
D
E
K
A
F
R
W
L
H
N
E
D
Q
M
A
V
E
K
L
S
D
G
I
R
K
F
A
A
D
A
I
K
L
E
R
M
L
T
E
R
M
F
S
------------------------------------
1
PsiBlast_PDB
37.04
26%
106
- C2 -
2CWN
-
TALDO_MOUSE
A:
[185-234]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
I
S
P
F
V
G
R
I
L
D
W
H
V
A
N
T
D
K
K
S
Y
E
P
------
Q
G
D
P
G
V
K
----
S
V
T
K
I
Y
N
Y
Y
K
K
F
G
Y
K
T
I
V
-
M
-
G
A
S
F
R
N
T
G
E
---
I
----
K
A
L
A
G
C
D
F
L
T
I
S
P
K
L
L
G
E
L
L
K
D
N
S
K
L
A
P
A
L
S
V
K
A
A
Q
T
S
D
S
E
K
I
H
L
D
E
K
A
F
R
W
L
H
N
E
D
Q
M
A
V
E
K
L
S
D
G
I
R
K
F
A
A
D
A
I
K
L
E
R
M
L
T
E
R
M
F
-------------------------------------
14
Fugue
36.45
21%
375
- C2 -
5CMZ
-
?
B:
[2-33]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
T
W
E
E
W
D
K
K
I
E
E
L
I
K
K
S
E
E
L
I
K
K
I
E
E
Q
I
K
K
Q
E
-----------------------------------------------------------------------------------------------------------------------------------------------------
17
Fugue
36.43
13%
411
- C2 -
3EFD
-
?
K:
[129-158]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
E
K
A
A
E
E
A
Y
T
R
T
T
R
A
L
H
E
R
F
D
R
L
E
R
M
L
D
D
N
---------------------------------------------------------------------------------------------------------------------------------------------------------
12
HHSearch
36.17
15%
-104
- C2 -
2GFP
-
EMRD_ECOLI
A:
[47-158]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
V
M
G
A
Y
L
L
T
Y
G
V
S
Q
L
F
Y
G
P
I
S
D
R
V
G
R
R
P
V
----------------------------------
I
L
V
G
M
S
I
-
F
M
L
A
T
L
V
A
V
T
T
---
S
----
S
L
T
V
L
I
A
A
S
A
M
Q
G
M
G
T
G
V
G
G
V
M
A
R
T
L
P
R
D
L
Y
E
R
T
Q
L
R
H
A
N
S
L
L
N
M
G
I
L
V
S
P
L
L
A
P
L
I
G
G
L
L
D
T
M
W
N
W
R
A
C
Y
L
F
L
L
V
L
C
A
G
V
T
F
S
M
A
R
W
M
P
E
T
R
P
V
D
A
P
R
T
R
L
L
T
S
Y
K
T
L
F
G
N
S
G
F
N
C
Y
L
L
M
L
I
G
9
HHSearch
34.72
11%
-103
- C2 -
1PW4
-
GLPT_ECOLI
A:
[67-181]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
A
L
S
G
I
S
I
A
Y
G
F
S
K
F
I
M
G
S
V
S
D
R
S
N
P
R
V
F
----------------------------------
L
P
A
G
L
I
L
-
A
A
A
V
M
L
F
M
G
F
V
---
P
W
A
T
S
S
I
A
V
M
F
V
L
L
F
L
C
G
W
F
Q
G
M
G
W
P
P
C
G
R
T
M
V
H
W
W
S
Q
K
E
R
G
G
I
V
S
V
W
N
C
A
H
N
V
G
G
G
I
P
P
L
L
F
L
L
G
M
A
W
F
N
D
W
H
A
A
L
Y
M
P
A
F
C
A
I
L
V
A
L
F
A
F
A
M
M
R
D
T
P
Q
S
C
G
L
P
P
I
E
E
Y
K
N
D
T
A
K
Q
I
F
M
Q
Y
V
L
P
N
K
L
L
19
Fugue
31.49
16%
306
- C2 -
2Y0M
-
B:
[29-70]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
I
L
E
N
L
D
D
S
V
F
S
K
R
H
A
K
L
E
L
D
E
K
R
R
K
R
W
D
I
Q
R
I
R
E
Q
R
I
L
Q
R
L
---------------------------------------------------------------------------------------------------------------------------------------------------
22
Fugue
31.22
21%
577
- C2 -
2XZE
-
CHMP3_HUMAN
Q:
[18-40]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
E
D
E
E
E
E
E
E
A
L
E
A
M
Q
S
R
L
A
T
L
R
S
-----------------------------------------------------------------------------------------------------------------------------------------------------------------
15
Fugue
31.05
12%
247
- C2 -
4YV4
-
SAS5_CAEEL
A:
[7-53]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
A
E
N
W
R
D
A
M
K
T
E
L
Q
T
I
R
T
E
I
Q
E
E
T
A
R
R
Q
E
E
L
N
A
Q
N
L
V
K
M
Q
E
L
M
S
N
F
F
-----------------------------------------------------------------------------------------------------------------------------------------------------