@TOME V2.2
(Nov 2016)
Ref.
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : NAC1_HUMAN: (2015-12-08 )
MYNMRRLSLSPTFSMGFHLLVTVSLLFSHVDHVIAETEMEGEGNETGECTGSYYCKKGVILPIWEPQDPSFGDKIARATVYFVAMVYMFLGVSIIADRFMSSIEVITSQEKEITIKKPNGETTKTTVRIWNETVSNLTLMALGSSAPEILLSVIEVCGHNFTAGDLGPSTIVGSAAFNMFIIIALCVYVVPDGETRKIKHLRVFFVTAAWSIFAYTWLYIILSVISPGVVEVWEGLLTFFFFPICVVFAWVADRRLLFYKYVYKRYRAGKQRGMIIEHEGDRPSSKTEIEMDGKVVNSHVENFLDGALVLEVDERDQDDEEARREMARILKELKQKHPDKEIEQLIELANYQVLSQQQKSRAFYRIQATRLMTGAGNILKRHAADQARKAVSMHEVNTEVTENDPVSKIFFEQGTYQCLENCGTVALTIIRRGGDLTNTVFVDFRTEDGTANAGSDYEFTEGTVVFKPGDTQKEIRVGIIDDDIFEEDENFLVHLSNVKVSSEASEDGILEANHVSTLACLGSPSTATVTIFDDDHAGIFTFEEPVTHVSESIGIMEVKVLRTSGARGNVIVPYKTIEGTARGGGEDFEDTCGELEFQNDEIVKTISVKVIDDEEYEKNKTFFLEIGEPRLVEMSEKKALLLNELGGFTITGKYLFGQPVFRKVHAREHPILSTVITIADEYDDKQPLTSKEEEERRIAEMGRPILGEHTKLEVIIEESYEFKSTVDKLIKKTNLALVVGTNSWREQFIEAITVSAGEDDDDDECGEEKLPSCFDYVMHFLTVFWKVLFAFVPPTEYWNGWACFIVSILMIGLLTAFIGDLASHFGCTIGLKDSVTAVVFVALGTSVPDTFASKVAATQDQYADASIGNVTGSNAVNVFLGIGVAWSIAAIYHAANGEQFKVSPGTLAFSVTLFTIFAFINVGVLLYRRRPEIGGELGGPRTAKLLTSCLFVLLWLLYIFFSSLEAYCHIKGF
Atome Classification :
(21 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430.......440.......450.-......460.......470.......480....-...490.......500....---...510.-------......520.......530.......540.......550.......560.......570.......580..-.....590.......600.......610.......620.......630.......640.......650.......660.......670.......680.......690.......700.......710.......720.......730.......740.......750.......760.......770.......780.......790.......800.......810.......820.......830.......840.......850.......860.......870.......880.......890.......900.......910.......920.......930.......940.......950.......960.......970.
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MYN
M
R
R
LSLSP
T
F
SM
G
F
H
L
L
V
T
V
S
L
L
F
S
H
V
D
H
V
I
A
E
TEMEGEGNETGECTG
S
Y
Y
CKK
G
V
I
L
P
I
WEPQDPS
F
G
D
K
I
A
R
A
T
V
Y
F
V
A
M
V
Y
M
F
L
G
V
S
I
I
A
D
R
F
M
S
S
I
E
V
ITSQE
K
E
I
T
I
KKPNGET
T
K
T
T
V
R
I
W
N
ETVS
N
L
T
L
M
ALGSS
A
P
E
I
L
L
S
V
I
E
V
CGHNFTAGDLG
P
S
T
I
V
G
S
A
A
F
N
M
F
I
I
I
A
L
C
V
YVVPDGET
R
K
I
K
H
L
R
V
F
F
V
T
A
A
W
S
I
F
A
Y
T
W
L
Y
I
I
L
S
V
IS
P
G
V
V
E
V
W
E
G
L
L
T
F
F
F
F
P
I
C
V
V
F
A
W
V
ADR
R
L
L
F
Y
K
Y
V
Y
K
R
Y
RAGKQR
G
M
I
I
EHEGDRPSSK
T
E
I
E
MD
G
K
V
V
N
S
H
V
E
N
FLD
G
A
L
V
L
E
VDERDQ
D
D
E
E
A
R
R
E
M
A
R
I
L
K
E
L
K
Q
KHP
D
K
E
I
E
Q
L
I
E
L
A
N
Y
Q
V
L
S
Q
Q
Q
KS
R
A
F
Y
R
I
Q
A
T
R
L
MTG
A
G
N
I
L
K
R
H
A
A
D
Q
A
R
K
A
V
S
M
HEVNTEVTENDPVS
K
I
F
FEQ
G
T
Y
Q
C
L
E
NC
G
T
V
A
L
T
I
I
RRGGDL
T
N
T
V
F
V
D
F
RTEDGTANA-GSD
Y
E
FTE
G
T
V
V
FKPGDT
Q
K
E
I
R
V
G
IIDDDIFE-EDE
N
F
L
V
H
L
SN
V
K
VSSEASE---DG
I
L
EAN-------H
V
S
T
L
A
CLGSPS
T
A
T
V
T
I
FDDDHA
G
I
F
TFE
E
P
V
T
H
V
S
ESI
G
I
M
E
V
K
V
L
RTSGARG
N
V
I
V
P
Y
K
TIEGTARGG-GE
D
F
E
D
T
CGELEFQND
E
I
V
K
T
I
S
V
K
V
IDDEEYEKN
K
T
F
F
L
EIGEP
R
L
V
E
M
S
E
K
K
A
L
L
L
N
ELG
G
F
T
I
T
GKYLFG
Q
P
V
F
R
K
V
H
AREHP
I
L
S
T
V
I
T
IADEYDDKQPLT
S
K
E
E
E
E
R
R
I
A
E
MGRPILGEH
T
K
L
E
V
I
IEESY
E
F
K
S
T
V
D
K
L
I
K
KT
N
L
A
L
V
V
GT
N
S
W
R
E
Q
F
I
E
A
I
T
VSAGEDDDDD
E
C
G
E
E
K
L
P
S
C
F
D
Y
V
M
H
F
L
T
V
F
W
K
V
L
F
A
FV
P
P
T
EYWN
G
W
A
C
F
I
V
S
I
L
M
I
G
L
L
T
A
F
I
G
D
L
A
S
HF
G
C
T
IGLKDS
V
T
A
V
V
F
V
ALGTSV
P
D
T
F
A
S
K
V
AATQDQYADASIGNVTGSN
A
V
N
V
F
L
GI
G
V
A
W
S
I
A
A
I
YHAANG
E
Q
F
K
VSPG
T
L
A
F
S
V
T
L
F
T
I
F
A
F
I
N
V
G
V
L
L
Y
RRRPEIGGELGG
P
R
T
A
K
L
L
T
S
C
L
F
V
L
L
W
L
L
Y
I
F
F
S
S
L
E
A
Y
C
H
IKGF
2
PsiBlast_PDB
92.17
98%
-27
- C2 -
2QVM
-
A:
[4-188]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
A
G
I
F
T
F
E
E
P
V
T
H
V
S
E
S
I
G
I
M
E
V
K
V
L
R
T
S
G
A
R
G
N
V
I
V
P
Y
K
T
I
E
G
T
A
R
G
G
-
G
E
D
F
E
D
T
C
G
E
L
E
F
Q
N
D
E
I
V
K
T
I
S
V
K
V
I
D
D
E
E
Y
E
K
N
K
T
F
F
L
E
I
G
E
P
R
L
V
---------------------------------------------------------------------
G
R
P
I
L
G
E
H
T
K
L
E
V
I
I
E
E
S
Y
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
PsiBlast_CBE
83.97
38%
-60
- C2 -
3RB5
1
?
B:
[10-260]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
-
R
M
Y
F
E
P
G
H
Y
T
V
M
E
N
C
G
E
F
E
V
R
V
V
R
R
-
G
D
I
S
T
Y
A
S
V
E
Y
E
T
Q
D
G
T
A
S
A
-
G
T
D
F
V
G
R
K
G
L
L
S
F
P
P
G
V
D
E
Q
R
F
R
I
E
V
I
D
D
D
V
F
E
-
E
D
E
C
F
Y
I
R
L
F
N
---------------------------
P
S
E
G
V
K
L
A
V
P
M
I
A
T
V
M
I
L
D
D
D
H
A
G
I
F
A
F
T
D
S
V
F
E
I
T
E
S
V
G
R
F
E
L
K
V
M
R
Y
S
G
A
R
G
T
V
I
V
P
Y
W
T
E
N
D
T
A
-
T
E
-
S
K
D
Y
E
G
A
R
G
E
L
V
F
E
N
N
E
S
E
K
F
I
D
L
F
I
L
E
E
------
V
S
F
K
V
H
I
G
E
P
R
L
A
P
D
D
E
L
A
A
K
I
-----------
K
E
V
E
K
K
P
V
-------------------------
Q
D
L
T
----
E
L
D
R
I
L
L
L
S
K
P
R
N
G
E
L
T
T
A
Y
V
R
I
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
83.13
38%
-50
- C2 -
3RB7
-
?
A:
[10-262]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
-
R
M
Y
F
E
P
G
H
Y
T
V
M
E
N
C
G
E
F
E
V
R
V
V
R
R
G
-
D
I
S
T
Y
A
S
V
E
Y
E
T
Q
D
G
T
A
S
A
-
G
T
D
F
V
G
R
K
G
L
L
S
F
P
P
G
V
D
E
Q
R
F
R
I
E
V
I
D
D
D
V
F
E
-
E
D
E
C
F
Y
I
R
L
F
N
P
---------------------------
S
E
G
V
K
L
A
V
P
M
I
A
T
V
M
I
L
D
D
D
H
A
G
I
F
A
F
T
D
S
V
F
E
I
T
E
S
V
G
R
F
E
L
K
V
M
R
Y
S
G
A
R
G
T
V
I
V
P
Y
W
T
E
N
D
T
A
T
E
S
--
K
D
Y
E
G
A
R
G
E
L
V
F
E
N
N
E
S
E
K
F
I
D
L
F
I
-----
Y
E
K
D
V
S
F
K
V
H
I
G
E
P
R
L
A
P
D
S
----------------------------
T
H
---
Y
P
K
I
K
E
V
--------
E
K
K
P
V
Q
D
L
T
E
L
D
R
-
I
L
L
L
S
K
P
R
N
G
E
L
T
T
A
Y
V
R
I
R
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
83.11
38%
-58
- C2 -
3RB5
1
?
A:
[10-261]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
-
R
M
Y
F
E
P
G
H
Y
T
V
M
E
N
C
G
E
F
E
V
R
V
V
R
R
-
G
D
I
S
T
Y
A
S
V
E
Y
E
T
Q
D
G
T
A
S
A
-
G
T
D
F
V
G
R
K
G
L
L
S
F
P
P
G
V
D
E
Q
R
F
R
I
E
V
I
D
D
D
V
F
E
-
E
D
E
C
F
Y
I
R
L
F
N
---------------------------
P
S
E
G
V
K
L
A
V
P
M
I
A
T
V
M
I
L
D
D
D
H
A
G
I
F
A
F
T
D
S
V
F
E
I
T
E
S
V
G
R
F
E
L
K
V
M
R
Y
S
G
A
R
G
T
V
I
V
P
Y
W
T
E
N
D
-------
K
D
Y
E
G
A
R
G
E
L
V
F
E
N
N
E
S
E
K
F
I
D
L
F
---------
D
V
S
F
K
V
H
I
G
E
P
R
L
A
P
D
D
E
L
A
A
K
I
-----------
K
E
V
E
K
K
P
V
-------------------------
Q
D
L
T
----
E
L
D
R
I
L
L
L
S
K
P
R
N
G
E
L
T
T
A
Y
V
R
I
R
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
HHSearch
83.04
44%
-45
- C2 -
3RB5
1
?
A:
[10-261]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
R
M
Y
F
E
P
G
H
Y
T
V
M
E
N
C
G
E
F
E
V
R
V
V
R
R
G
D
-
I
S
T
Y
A
S
V
E
Y
E
T
Q
D
G
T
A
S
A
-
G
T
D
F
V
G
R
K
G
L
L
S
F
P
P
G
V
D
E
Q
R
F
R
I
E
V
I
D
D
D
V
F
E
-
E
D
E
C
F
Y
I
R
L
F
N
P
S
E
---------------------------
G
V
K
L
A
V
P
M
I
A
T
V
M
I
L
D
D
D
H
A
G
I
F
A
F
T
D
S
V
F
E
I
T
E
S
V
G
R
F
E
L
K
V
M
R
Y
S
G
A
R
G
T
V
I
V
P
Y
W
T
E
N
D
-------
K
D
Y
E
G
A
R
G
E
L
V
F
E
N
N
E
S
E
K
F
I
D
L
F
---------
D
V
S
F
K
V
H
I
G
E
P
R
L
A
P
D
D
E
L
A
A
K
I
K
----------------------------------------
E
V
E
K
K
P
V
Q
D
L
T
E
L
D
R
I
L
L
L
S
K
P
R
N
G
E
L
T
T
A
Y
V
R
I
R
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
82.37
98%
-17
- C2 -
2QVK
-
NAC1_CANFA
A:
[501-654]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
A
G
I
F
T
F
E
E
P
V
T
H
V
S
E
S
I
G
I
M
E
V
K
V
L
R
T
S
G
A
R
G
N
V
I
V
P
Y
K
T
I
E
G
T
A
R
G
G
-
G
E
D
F
E
D
T
C
G
E
L
E
F
Q
N
D
E
I
V
K
T
I
S
V
K
V
I
D
D
E
E
Y
E
K
N
K
T
F
F
L
E
I
G
E
P
R
L
V
E
--------------------------------------------------------------------
G
R
P
I
L
G
E
H
T
K
L
E
V
I
I
E
E
S
Y
E
F
K
S
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
25
HHSearch
82.19
97%
-17
- C2 -
2QVK
-
NAC1_CANFA
A:
[501-654]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
A
G
I
F
T
F
E
E
P
V
T
H
V
S
E
S
I
G
I
M
E
V
K
V
L
R
T
S
G
A
R
G
N
V
I
V
P
Y
K
T
I
E
G
T
A
R
G
G
-
G
E
D
F
E
D
T
C
G
E
L
E
F
Q
N
D
E
I
V
K
T
I
S
V
K
V
I
D
D
E
E
Y
E
K
N
K
T
F
F
L
E
I
G
E
P
R
L
V
E
--------------------------------------------------------------------
G
R
P
I
L
G
E
H
T
K
L
E
V
I
I
E
E
S
Y
E
F
K
S
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
80.41
98%
-37
- C2 -
2DPK
2
A:
[13-145]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
V
S
K
I
F
F
E
Q
G
T
Y
Q
C
L
E
N
C
G
T
V
A
L
T
I
I
R
R
G
G
D
L
T
N
T
V
F
V
D
F
R
T
E
D
G
T
A
N
A
-
G
S
D
Y
E
F
T
E
G
T
V
V
F
K
P
G
E
T
Q
K
E
I
R
V
G
I
I
D
D
D
I
F
E
-
E
D
E
N
F
L
V
H
L
S
N
V
K
V
S
S
E
----------------------
S
A
L
A
C
L
G
S
P
S
T
A
T
V
T
I
F
D
D
D
H
A
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
79.07
97%
-46
- C2 -
3GIN
-
NAC1_CANFA
A:
[21-152]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
V
S
K
I
F
F
E
Q
G
T
Y
Q
C
L
E
N
C
G
T
V
A
L
T
I
I
R
R
G
G
D
L
T
N
T
V
F
V
D
F
R
T
E
D
G
T
A
N
A
-
G
S
D
Y
E
F
T
E
G
T
V
V
F
K
P
G
E
T
Q
K
E
I
R
V
G
I
I
D
D
D
I
F
E
-
E
D
K
N
F
L
V
H
L
S
N
V
K
V
--------------------------
A
L
A
C
L
G
S
P
S
T
A
T
V
T
I
F
D
D
D
H
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
32
HHSearch
78.92
96%
-46
- C2 -
3GIN
-
NAC1_CANFA
A:
[21-152]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
V
S
K
I
F
F
E
Q
G
T
Y
Q
C
L
E
N
C
G
T
V
A
L
T
I
I
R
R
G
G
D
L
T
N
T
V
F
V
D
F
R
T
E
D
G
T
A
N
A
-
G
S
D
Y
E
F
T
E
G
T
V
V
F
K
P
G
E
T
Q
K
E
I
R
V
G
I
I
D
D
D
I
F
E
-
E
D
K
N
F
L
V
H
L
S
N
V
K
V
--------------------------
A
L
A
C
L
G
S
P
S
T
A
T
V
T
I
F
D
D
D
H
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
77.76
81%
-12
- C2 -
2KLS
-
?
A:
[502-657]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
G
I
F
T
F
E
E
P
V
T
H
V
S
E
S
I
G
I
M
E
V
K
V
L
R
T
S
G
A
R
G
N
V
I
V
P
Y
K
T
I
E
G
T
A
R
G
G
-
G
E
D
F
E
D
T
C
G
E
L
E
F
Q
N
D
E
I
V
K
T
I
S
V
K
V
I
D
D
E
E
Y
E
K
N
K
T
F
F
L
E
I
G
E
P
R
L
V
E
M
S
E
K
K
-------
G
G
F
T
I
T
----------------------------
E
E
Y
D
D
K
Q
P
L
T
S
K
E
E
E
E
R
R
I
A
E
M
G
R
P
I
L
G
E
H
T
K
L
E
V
I
I
E
E
S
Y
E
F
K
S
T
V
D
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
74.57
69%
-9
- C2 -
2KLT
-
?
A:
[502-656]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
G
I
F
T
F
E
E
P
V
T
H
V
S
E
S
I
G
I
M
E
V
K
V
L
R
T
S
G
A
R
G
N
V
I
V
P
Y
K
T
I
E
G
T
A
R
G
G
-
G
E
D
F
E
D
T
C
G
E
L
E
F
Q
N
D
E
I
V
K
I
I
T
I
R
I
F
D
R
E
E
Y
E
K
E
C
S
F
S
L
V
L
E
E
P
K
W
I
R
R
G
M
K
--------
G
G
F
T
I
T
----------------------------
E
E
Y
D
D
K
Q
P
L
T
S
K
E
E
E
E
R
R
I
A
E
M
G
R
P
I
L
G
E
H
T
K
L
E
V
I
I
E
E
S
Y
E
F
K
S
T
V
D
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
28
HHSearch
71.30
32%
-23
- C2 -
2LT9
-
?
A:
[529-669]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
G
I
F
T
F
E
C
D
T
I
H
V
S
E
S
I
G
V
M
E
V
K
V
L
R
T
S
G
-
A
R
G
T
V
I
V
P
F
R
T
V
E
G
T
A
K
G
G
G
E
D
F
E
D
A
Y
G
E
L
E
F
K
N
D
E
T
V
K
T
I
R
V
K
I
V
D
E
E
E
Y
E
-
R
Q
E
N
F
F
I
A
L
G
E
P
K
W
M
E
R
G
I
S
EVT
D
R
K
L
T
V
E
EE
E
A
K
R
I
A
E
M
G
K
P
V
L
G
E
H
P
K
L
E
V
I
I
E
E
S
Y
E
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
27
HHSearch
71.11
69%
-17
- C2 -
2LT9
-
?
A:
[528-675]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
A
G
I
F
T
F
E
C
D
T
I
H
V
S
E
S
I
G
V
M
E
V
K
V
L
R
T
S
G
A
R
G
T
V
I
V
P
F
R
T
V
E
G
T
A
K
-
G
G
G
E
D
F
E
D
A
Y
G
E
L
E
F
K
N
D
E
T
V
K
T
I
R
V
K
I
V
D
E
E
E
Y
E
R
Q
E
N
F
F
I
A
L
G
E
P
K
W
M
E
R
G
I
S
E
V
T
--------------------------------------------
D
R
K
L
T
V
E
E
E
E
A
K
R
I
A
E
M
G
K
P
V
L
G
E
H
P
K
L
E
V
I
I
E
E
S
Y
E
F
K
S
T
V
D
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
69.74
54%
-21
- C2 -
2LT9
-
?
A:
[529-675]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
G
I
F
T
F
E
C
D
T
I
H
V
S
E
S
I
G
V
M
E
V
K
V
L
R
T
S
G
A
R
G
T
V
I
V
P
F
R
T
V
E
G
T
A
K
G
G
-
G
E
D
F
E
D
A
Y
G
E
L
E
F
K
N
D
E
T
V
K
T
I
R
V
K
I
V
D
E
E
E
Y
E
R
Q
E
N
F
F
I
A
L
G
E
P
K
W
M
E
R
G
------------------------------------------
I
S
E
V
T
D
R
K
--
L
T
V
E
E
E
E
A
K
R
I
A
E
M
G
K
P
V
L
G
E
H
P
K
L
E
V
I
I
E
E
S
Y
E
F
K
S
T
V
D
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
66.39
36%
-13
- C2 -
3E9U
-
?
A:
[555-708]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
I
F
A
F
T
D
S
V
F
E
I
T
E
S
V
G
R
F
E
L
K
V
M
R
Y
S
G
A
R
G
T
V
I
V
P
Y
W
T
E
N
D
T
A
-
T
E
-
S
K
D
Y
E
G
A
R
G
E
L
V
F
E
N
N
E
S
E
K
F
I
D
L
F
I
L
E
E
S
S
Y
E
K
D
V
S
F
K
V
H
I
G
E
P
R
L
A
P
D
D
-----------
G
L
A
A
K
I
K
E
V
E
K
K
P
V
-------------------------
Q
D
L
T
----
E
L
D
R
I
L
L
L
S
K
P
R
N
G
E
L
T
T
A
Y
V
R
I
R
E
S
Q
E
F
K
A
T
V
D
K
L
V
A
K
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
41
Fugue
66.20
40%
5
- C2 -
3E9U
-
?
A:
[548-709]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
G
R
G
S
E
F
G
I
F
A
F
T
D
S
V
F
E
I
T
E
S
V
G
R
F
E
L
K
V
M
R
Y
S
G
A
R
G
T
V
I
V
P
Y
W
T
E
N
D
T
A
T
E
S
--
K
D
Y
E
G
A
R
G
E
L
V
F
E
N
N
E
S
E
K
F
I
D
L
F
I
L
E
E
S
S
Y
E
K
D
V
S
F
K
V
H
I
G
E
P
R
L
A
P
D
D
G
L
A
A
K
I
K
E
V
----------------------------------------
E
K
K
P
V
Q
D
L
T
E
L
D
R
I
L
L
L
S
K
P
R
N
G
E
L
T
T
A
Y
V
R
I
R
E
S
Q
E
F
K
A
T
V
D
K
L
V
A
K
A
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
34
HHSearch
61.43
33%
-37
- C2 -
3FSO
-
ITB4_HUMAN
A:
[988-1105]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
R
D
V
V
S
F
E
Q
P
E
F
S
V
S
R
G
D
Q
V
A
R
I
P
V
I
R
R
V
L
D
-
G
G
K
S
Q
V
S
Y
R
T
Q
D
G
T
A
Q
G
-
N
R
D
Y
I
P
V
E
G
E
L
L
F
Q
P
G
E
A
W
K
E
L
Q
V
K
L
L
E
L
----R
Q
V
R
R
F
H
V
Q
L
S
N
P
K
F
---------------------------
G
A
H
L
G
Q
P
H
S
T
T
I
I
I
R
D
P
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
35
HHSearch
61.02
42%
-20
- C2 -
3E9T
-
?
A:
[3-112]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
R
M
Y
F
E
P
G
H
Y
T
V
M
E
N
C
G
E
F
E
V
R
V
V
R
R
G
D
-
I
S
T
Y
A
S
V
E
Y
E
T
Q
D
G
T
A
S
A
-
G
T
D
F
V
G
R
K
G
L
L
S
F
P
P
G
V
D
E
Q
R
F
R
I
E
V
I
D
D
D
V
F
E
-
E
D
E
C
F
Y
I
R
L
F
N
P
S
E
---------------------------
G
V
K
L
A
V
P
M
I
A
T
V
M
I
L
D
D
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
30
HHSearch
60.03
42%
-24
- C2 -
3EAD
1
?
A:
[5-115]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
R
M
Y
F
E
P
G
H
Y
T
V
M
E
N
C
G
E
F
E
V
R
V
V
R
R
G
D
-
I
S
T
Y
A
S
V
E
Y
E
T
Q
D
G
T
A
S
A
-
G
T
D
F
V
G
R
K
G
L
L
S
F
P
P
G
V
D
E
Q
R
F
R
I
E
V
I
D
D
D
V
F
E
-
E
D
E
C
F
Y
I
R
L
F
N
P
S
E
---------------------------
G
V
K
L
A
V
P
M
I
A
T
V
M
I
L
D
D
D
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
PsiBlast_CBE
59.85
40%
-1
- C2 -
3EAD
1
?
C:
[5-116]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
-
R
M
Y
F
E
P
G
H
Y
T
V
M
E
N
C
G
E
F
E
V
R
V
V
R
R
G
-
D
I
S
T
Y
A
S
V
E
Y
E
T
Q
D
G
T
A
S
A
-
G
T
D
F
V
G
R
K
G
L
L
S
F
P
P
G
V
D
E
Q
R
F
R
I
E
V
I
D
D
D
V
F
E
-
E
D
E
C
F
Y
I
R
L
F
N
---
P
S
E
G
V
K
------------------------
L
A
V
P
M
I
A
T
V
M
I
L
D
D
D
H
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------