@TOME V2.2
(Nov 2016)
Ref.
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : NAC2_HUMAN: (2015-12-08 )
MAPLALVGVTLLLAAPPCSGAATPTPSLPPPPANDSDTSTGGCQGSYRCQPGVLLPVWEPDDPSLGDKAARAVVYFVAMVYMFLGVSIIADRFMAAIEVITSKEKEITITKANGETSVGTVRIWNETVSNLTLMALGSSAPEILLSVIEVCGHNFQAGELGPGTIVGSAAFNMFVVIAVCIYVIPAGESRKIKHLRVFFVTASWSIFAYVWLYLILAVFSPGVVQVWEALLTLVFFPVCVVFAWMADKRLLFYKYVYKRYRTDPRSGIIIGAEGDPPKSIELDGTFVGAEAPGELGGLGPGPAEARELDASRREVIQILKDLKQKHPDKDLEQLVGIANYYALLHQQKSRAFYRIQATRLMTGAGNVLRRHAADASRRAAPAEGAGEDEDDGASRIFFEPSLYHCLENCGSVLLSVTCQGGEGNSTFYVDYRTEDGSAKAGSDYEYSEGTLVFKPGETQKELRIGIIDDDIFEEDEHFFVRLLNLRVGDAQGMFEPDGGGRPKGRLVAPLLATVTILDDDHAGIFSFQDRLLHVSECMGTVDVRVVRSSGARGTVRLPYRTVDGTARGGGVHYEDACGELEFGDDETMKTLQVKIVDDEEYEKKDNFFIELGQPQWLKRGISALLLNQGDGDRKLTAEEEEARRIAEMGKPVLGENCRLEVIIEESYDFKNTVDKLIKKTNLALVIGTHSWREQFLEAITVSAGDEEEEEDGSREERLPSCFDYVMHFLTVFWKVLFACVPPTEYCHGWACFGVSILVIGLLTALIGDLASHFGCTVGLKDSVNAVVFVALGTSIPDTFASKVAALQDQCADASIGNVTGSNAVNVFLGLGVAWSVAAVYWAVQGRPFEVRTGTLAFSVTLFTVFAFVGIAVLLYRRRPHIGGELGGPRGPKLATTALFLGLWLLYILFASLEAYCHIRGF
Atome Classification :
(21 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430.......440........450.......460.......470.......480.....---..490-----........------500.......510.......520.......530.......540.......550.......560.......570.......580.......590.......600.......610.....----..620.--......630.......640.......650.......660.......670.......680.......690.......700.......710.......720.......730.......740.......750.......760.......770.......780.......790.......800.......810.......820.......830.......840.......850.......860.......870.......880.......890.......900.......910.......920
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MA
P
L
A
L
V
G
V
T
L
L
L
AAPPCSGAATPTPSLPPPPANDSDTSTGGCQGSYRCQP
G
V
L
L
P
VWEPDDPSL
G
D
K
A
A
R
A
V
V
Y
F
V
A
M
V
Y
M
F
L
G
V
S
I
I
A
D
R
F
M
A
A
I
E
V
I
TSKE
K
E
I
T
I
T
KANGETS
V
G
T
V
R
I
W
N
E
TVS
N
L
T
L
M
ALGSS
A
P
E
I
L
L
S
V
I
E
V
CGHNFQAGELGPG
T
I
V
G
S
A
A
F
N
M
F
V
V
I
A
V
C
I
Y
V
IPAGES
R
K
I
K
H
L
R
V
F
F
V
TA
S
W
S
I
F
A
Y
V
W
L
Y
L
I
L
A
VFS
P
G
V
V
Q
V
W
E
A
L
L
T
L
V
F
F
P
V
C
V
V
F
A
W
M
ADK
R
L
L
F
Y
K
Y
V
Y
K
R
YRTDPRS
G
I
I
I
GAEGDPP
K
S
I
E
LD
G
T
F
VGAEAPGELGGLGPG
P
A
E
A
R
E
L
D
A
S
R
R
E
V
I
Q
I
L
K
D
L
K
Q
KHP
D
K
D
L
E
Q
L
V
G
I
A
N
Y
Y
A
L
L
H
Q
QKS
R
A
F
Y
R
I
Q
A
T
R
L
MTG
A
G
N
V
L
R
R
H
AADASRRAAPAEGAGEDEDDGA
S
R
I
F
FE
P
S
L
Y
H
C
L
E
N
C
G
S
V
L
L
S
V
T
C
QGGEGN
S
T
F
Y
V
D
Y
RTEDGSAKA-GSDYEYSE
G
T
L
V
FKPGET
Q
K
E
L
R
I
G
IIDDDIFEE
D
E
H
F
F
V
R
L
L
NLRV---GDAQ------GMFEPDGG------GRPKG
R
L
V
A
P
L
L
A
T
V
T
I
LDDDHA
G
I
F
S
F
Q
D
R
L
L
H
V
S
E
CMG
T
V
D
V
R
V
V
RSSGARG
T
V
R
L
P
Y
R
TVDGTARGGGVHYEDACGELEFGDDE
T
M
K
T
L
Q
V
K
IVD
D
E
E
YEKKD
N
F
F
I
ELGQ
P
Q
W
L
----
K
R
G
I
S
A
--
L
L
LNQGDGDRKLT
A
E
E
E
E
A
R
R
I
A
E
MGKPVLGEN
C
R
L
E
V
I
I
EESYD
F
K
N
T
V
D
K
L
I
K
KT
N
L
A
L
V
I
GT
H
S
W
R
E
Q
F
L
E
A
I
TVSAGDEEEEEDG
S
R
E
ER
L
P
S
C
F
D
Y
V
M
H
F
L
T
V
F
W
K
V
L
F
A
CV
P
P
T
E
Y
CH
G
W
A
C
F
G
V
S
I
L
V
I
G
L
L
T
A
L
I
G
D
L
A
S
HF
G
C
TVGLKDSV
N
A
V
V
F
V
A
LGTSI
P
D
T
F
A
S
K
V
A
A
L
Q
D
QCADASIGNVTGSN
A
V
N
V
F
LGL
G
V
A
W
S
V
A
A
V
Y
W
AVQG
R
P
F
E
V
R
T
G
T
L
A
F
S
V
T
L
F
T
V
F
A
F
V
G
I
A
V
L
L
Y
RRRPHIGGELGGPRGP
K
L
A
T
T
A
L
F
L
G
L
W
L
L
Y
I
L
F
A
S
L
E
A
Y
C
H
IRGF
23
PsiBlast_CBE
94.69
40%
-62
- C2 -
3RB5
1
?
B:
[10-260]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
R
M
Y
F
E
P
G
H
Y
T
V
M
E
N
C
G
E
F
E
V
R
V
-
V
R
R
G
D
I
S
T
Y
A
S
V
E
Y
E
T
Q
D
G
T
A
S
A
-
G
T
D
F
V
G
R
K
G
L
L
S
F
P
P
G
V
D
E
Q
R
F
R
I
E
V
I
D
D
D
V
F
E
E
D
E
C
F
Y
I
R
L
F
N
--------------------
P
S
E
G
------
V
K
----
L
A
V
P
M
I
A
T
V
M
I
L
D
D
D
H
A
G
I
F
A
F
T
D
S
V
F
E
I
T
E
S
V
G
R
F
E
L
K
V
M
R
Y
S
G
A
R
G
T
V
I
V
P
Y
W
T
E
N
D
T
A
T
E
S
K
-
D
Y
E
G
A
R
G
E
L
V
F
E
N
N
E
S
E
K
F
I
D
L
F
I
L
E
E
------
V
S
F
K
V
H
I
G
E
P
R
L
A
----
P
D
D
E
L
A
--
A
K
I
K
E
--
V
E
K
K
P
V
Q
D
L
T
E
L
D
R
I
L
L
L
S
K
P
R
N
G
E
L
T
T
A
Y
V
R
I
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
94.13
40%
-49
- C2 -
3RB7
-
?
A:
[10-262]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
R
M
Y
F
E
P
G
H
Y
T
V
M
E
N
C
G
E
F
E
V
R
V
-
V
R
R
G
D
I
S
T
Y
A
S
V
E
Y
E
T
Q
D
G
T
A
S
A
-
G
T
D
F
V
G
R
K
G
L
L
S
F
P
P
G
V
D
E
Q
R
F
R
I
E
V
I
D
D
D
V
F
E
E
D
E
C
F
Y
I
R
L
F
N
--------------------
P
S
E
G
------
V
K
----
L
A
V
P
M
I
A
T
V
M
I
L
D
D
D
H
A
G
I
F
A
F
T
D
S
V
F
E
I
T
E
S
V
G
R
F
E
L
K
V
M
R
Y
S
G
A
R
G
T
V
I
V
P
Y
W
T
E
N
D
T
A
T
E
S
K
-
D
Y
E
G
A
R
G
E
L
V
F
E
N
N
E
S
E
K
F
I
D
L
F
I
-----
Y
E
K
D
V
S
F
K
V
H
I
G
E
P
R
L
A
----
P
D
S
T
H
Y
--
P
K
I
K
E
--
V
E
K
K
P
V
Q
D
L
T
E
L
D
R
I
L
L
L
S
K
P
R
N
G
E
L
T
T
A
Y
V
R
I
R
E
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
27
HHSearch
90.13
42%
-55
- C2 -
3RB5
1
?
A:
[10-261]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
R
M
Y
F
E
P
G
H
Y
T
V
M
E
N
C
G
E
F
E
V
R
V
V
R
R
G
D
I
-
S
T
Y
A
S
V
E
Y
E
T
Q
D
G
T
A
S
A
-
G
T
D
F
V
G
R
K
G
L
L
S
F
P
P
G
V
D
E
Q
R
F
R
I
E
V
I
D
D
D
V
F
E
E
D
E
C
F
Y
I
R
L
F
N
P
S
------------------------------
E
G
V
K
L
A
V
P
M
I
A
T
V
M
I
L
D
D
D
H
A
G
I
F
A
F
T
D
S
V
F
E
I
T
E
S
V
G
R
F
E
L
K
V
M
R
Y
S
G
A
R
G
T
V
I
V
P
Y
W
T
E
N
D
------
K
D
Y
E
G
A
R
G
E
L
V
F
E
N
N
E
S
E
K
F
I
D
L
F
---------
D
V
S
F
K
V
H
I
G
E
P
R
L
A
----
P
D
D
E
L
A
--
A
K
I
K
--
E
V
E
K
K
P
V
Q
D
L
T
E
L
D
R
I
L
L
L
S
K
P
R
N
G
E
L
T
T
A
Y
V
R
I
R
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
88.46
40%
-53
- C2 -
3RB5
1
?
A:
[10-261]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
R
M
Y
F
E
P
G
H
Y
T
V
M
E
N
C
G
E
F
E
V
R
V
-
V
R
R
G
D
I
S
T
Y
A
S
V
E
Y
E
T
Q
D
G
T
A
S
A
-
G
T
D
F
V
G
R
K
G
L
L
S
F
P
P
G
V
D
E
Q
R
F
R
I
E
V
I
D
D
D
V
F
E
E
D
E
C
F
Y
I
R
L
F
N
--------------------
P
S
E
G
------
V
K
----
L
A
V
P
M
I
A
T
V
M
I
L
D
D
D
H
A
G
I
F
A
F
T
D
S
V
F
E
I
T
E
S
V
G
R
F
E
L
K
V
M
R
Y
S
G
A
R
G
T
V
I
V
P
Y
W
T
E
N
D
-----
K
-
D
Y
E
G
A
R
G
E
L
V
F
E
N
N
E
S
E
K
F
I
D
L
F
---------
D
V
S
F
K
V
H
I
G
E
P
R
L
A
----
P
D
D
E
L
A
--
A
K
I
K
E
--
V
E
K
K
P
V
Q
D
L
T
E
L
D
R
I
L
L
L
S
K
P
R
N
G
E
L
T
T
A
Y
V
R
I
R
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
84.66
47%
-40
- C2 -
2QVM
-
A:
[4-188]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
A
G
I
F
T
F
E
E
P
V
T
H
V
S
E
S
I
G
I
M
E
V
K
V
L
R
T
S
G
A
R
G
N
V
I
V
P
Y
K
T
I
E
G
T
A
R
G
G
G
E
D
F
E
D
T
C
G
E
L
E
F
Q
N
D
E
I
V
K
T
I
S
V
K
V
I
D
D
E
E
Y
E
K
N
K
T
F
F
L
E
I
G
E
P
R
L
V
-------------------------------------
G
R
P
I
L
G
E
H
T
K
L
E
V
I
I
E
E
S
Y
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
81.74
56%
-35
- C2 -
2KLS
-
?
A:
[502-657]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
G
I
F
T
F
E
E
P
V
T
H
V
S
E
S
I
G
I
M
E
V
K
V
L
R
T
S
G
A
R
G
N
V
I
V
P
Y
K
T
I
E
G
T
A
R
G
G
G
E
D
F
E
D
T
C
G
E
L
E
F
Q
N
D
E
I
V
K
T
I
S
V
K
V
I
D
D
E
E
Y
E
K
N
K
T
F
F
L
E
I
G
E
P
R
L
V
EMSE
K
K
G
-
G
F
--
T
I
T
E
E
Y
D
D
K
Q
P
L
T
S
K
E
E
E
E
R
R
I
A
E
M
G
R
P
I
L
G
E
H
T
K
L
E
V
I
I
E
E
S
Y
E
F
K
S
T
V
D
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
31
HHSearch
80.44
68%
-35
- C2 -
2LT9
-
?
A:
[528-675]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
A
G
I
F
T
F
E
C
D
T
I
H
V
S
E
S
I
G
V
M
E
V
K
V
L
R
T
S
G
A
R
G
T
V
I
V
P
F
R
T
V
E
G
T
A
K
G
G
G
E
D
F
E
D
A
Y
G
E
L
E
F
K
N
D
E
T
V
K
T
I
R
V
K
I
V
D
E
E
E
Y
E
R
Q
E
N
F
F
I
A
L
G
E
P
K
W
M
----
E
R
G
I
S
E
--
V
T
------
D
R
K
L
T
V
E
E
E
E
A
K
R
I
A
E
M
G
K
P
V
L
G
E
H
P
K
L
E
V
I
I
E
E
S
Y
E
F
K
S
T
V
D
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
29
HHSearch
80.10
56%
-26
- C2 -
2QVK
-
NAC1_CANFA
A:
[501-654]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
A
G
I
F
T
F
E
E
P
V
T
H
V
S
E
S
I
G
I
M
E
V
K
V
L
R
T
S
G
A
R
G
N
V
I
V
P
Y
K
T
I
E
G
T
A
R
G
G
G
E
D
F
E
D
T
C
G
E
L
E
F
Q
N
D
E
I
V
K
T
I
S
V
K
V
I
D
D
E
E
Y
E
K
N
K
T
F
F
L
E
I
G
E
P
R
L
V
----
E
--------------------------------
G
R
P
I
L
G
E
H
T
K
L
E
V
I
I
E
E
S
Y
E
F
K
S
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
79.77
54%
-36
- C2 -
2KLT
-
?
A:
[502-656]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
G
I
F
T
F
E
E
P
V
T
H
V
S
E
S
I
G
I
M
E
V
K
V
L
R
T
S
G
A
R
G
N
V
I
V
P
Y
K
T
I
E
G
T
A
R
G
G
G
E
D
F
E
D
T
C
G
E
L
E
F
Q
N
D
E
I
V
K
I
I
T
I
R
I
F
D
R
E
E
Y
E
K
E
C
S
F
S
L
V
L
E
E
P
K
W
I
----
R
R
G
M
K
G
GF
T
I
T
E
E
Y
D
D
K
Q
P
L
T
S
K
E
E
E
E
R
R
I
A
E
M
G
R
P
I
L
G
E
H
T
K
L
E
V
I
I
E
E
S
Y
E
F
K
S
T
V
D
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
79.03
65%
-35
- C2 -
2LT9
-
?
A:
[529-675]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
G
I
F
T
F
E
C
D
T
I
H
V
S
E
S
I
G
V
M
E
V
K
V
L
R
T
S
G
A
R
G
T
V
I
V
P
F
R
T
V
E
G
T
A
K
G
G
G
E
D
F
E
D
A
Y
G
E
L
E
F
K
N
D
E
T
V
K
T
I
R
V
K
I
V
D
E
E
E
Y
E
R
Q
E
N
F
F
I
A
L
G
E
P
K
W
M
----
E
R
G
I
S
E
--
V
T
------
D
R
K
L
T
V
E
E
E
E
A
K
R
I
A
E
M
G
K
P
V
L
G
E
H
P
K
L
E
V
I
I
E
E
S
Y
E
F
K
S
T
V
D
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
77.84
56%
-51
- C2 -
3GIN
-
NAC1_CANFA
A:
[23-152]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
K
I
F
F
E
Q
G
T
Y
Q
C
L
E
N
C
G
T
V
A
L
T
I
I
R
R
G
G
D
L
T
N
T
V
F
V
D
F
R
T
E
D
G
T
A
N
A
-
G
S
D
Y
E
F
T
E
G
T
V
V
F
K
P
G
E
T
Q
K
E
I
R
V
G
I
I
D
D
D
I
F
E
E
D
K
N
F
L
V
H
L
S
N
V
K
V
-----------------------------
A
L
A
C
L
G
S
P
S
T
A
T
V
T
I
F
D
D
D
H
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
34
HHSearch
77.73
55%
-49
- C2 -
3GIN
-
NAC1_CANFA
A:
[21-152]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
V
S
K
I
F
F
E
Q
G
T
Y
Q
C
L
E
N
C
G
T
V
A
L
T
I
I
R
R
G
G
D
L
T
N
T
V
F
V
D
F
R
T
E
D
G
T
A
N
A
-
G
S
D
Y
E
F
T
E
G
T
V
V
F
K
P
G
E
T
Q
K
E
I
R
V
G
I
I
D
D
D
I
F
E
E
D
K
N
F
L
V
H
L
S
N
V
K
V
-----------------------------
A
L
A
C
L
G
S
P
S
T
A
T
V
T
I
F
D
D
D
H
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
77.31
47%
-26
- C2 -
2QVK
-
NAC1_CANFA
A:
[501-654]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
A
G
I
F
T
F
E
E
P
V
T
H
V
S
E
S
I
G
I
M
E
V
K
V
L
R
T
S
G
A
R
G
N
V
I
V
P
Y
K
T
I
E
G
T
A
R
G
G
G
E
D
F
E
D
T
C
G
E
L
E
F
Q
N
D
E
I
V
K
T
I
S
V
K
V
I
D
D
E
E
Y
E
K
N
K
T
F
F
L
E
I
G
E
P
R
L
V
----
E
--------------------------------
G
R
P
I
L
G
E
H
T
K
L
E
V
I
I
E
E
S
Y
E
F
K
S
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
77.02
57%
-52
- C2 -
2DPK
2
A:
[15-145]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
K
I
F
F
E
Q
G
T
Y
Q
C
L
E
N
C
G
T
V
A
L
T
I
I
R
R
G
G
D
L
T
N
T
V
F
V
D
F
R
T
E
D
G
T
A
N
A
-
G
S
D
Y
E
F
T
E
G
T
V
V
F
K
P
G
E
T
Q
K
E
I
R
V
G
I
I
D
D
D
I
F
E
E
D
E
N
F
L
V
H
L
S
N
V
K
V
S
S
E-------------------------
S
A
L
A
C
L
G
S
P
S
T
A
T
V
T
I
F
D
D
D
H
A
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
32
HHSearch
72.88
28%
-44
- C2 -
2LT9
-
?
A:
[528-669]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
A
G
I
F
T
F
E
C
D
T
I
H
V
S
E
S
I
G
V
M
E
V
K
V
L
R
T
S
G
A
-
R
G
T
V
I
V
P
F
R
T
V
E
G
T
A
K
G
G
G
E
D
F
E
D
A
Y
G
E
L
E
F
K
N
D
E
T
V
K
T
I
R
V
K
I
V
D
E
E
E
Y
E
R
Q
E
N
F
F
I
A
L
G
E
P
K
W
---
M
E
R
G
ISEVTD
R
K
L
T
V
E
E
E
E
A
K
R
I
A
E
M
G
K
P
V
L
G
E
H
P
K
L
E
V
I
I
E
E
S
Y
E
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
35
HHSearch
70.08
44%
-44
- C2 -
3EAD
1
?
A:
[5-115]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
R
M
Y
F
E
P
G
H
Y
T
V
M
E
N
C
G
E
F
E
V
R
V
V
R
R
G
D
I
-
S
T
Y
A
S
V
E
Y
E
T
Q
D
G
T
A
S
A
-
G
T
D
F
V
G
R
K
G
L
L
S
F
P
P
G
V
D
E
Q
R
F
R
I
E
V
I
D
D
D
V
F
E
E
D
E
C
F
Y
I
R
L
F
N
P
S
------------------------------
E
G
V
K
L
A
V
P
M
I
A
T
V
M
I
L
D
D
D
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
69.83
37%
-17
- C2 -
3E9U
-
?
A:
[555-708]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
I
F
A
F
T
D
S
V
F
E
I
T
E
S
V
G
R
F
E
L
K
V
M
R
Y
S
G
A
R
G
T
V
I
V
P
Y
W
T
E
N
D
T
A
T
E
S
K
-
D
Y
E
G
A
R
G
E
L
V
F
E
N
N
E
S
E
K
F
I
D
L
F
I
L
E
E
S
S
Y
E
K
D
V
S
F
K
V
H
I
G
E
P
R
L
A
P---
D
D
G
L
A
A
--
K
I
---
K
E
V
E
K
K
P
V
Q
D
L
T
E
L
D
R
I
L
L
L
S
K
P
R
N
G
E
L
T
T
A
Y
V
R
I
R
E
S
Q
E
F
K
A
T
V
D
K
L
V
A
K
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
44
Fugue
69.72
35%
-11
- C2 -
3E9U
-
?
A:
[548-709]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
G
R
G
S
E
F
G
I
F
A
F
T
D
S
V
F
E
I
T
E
S
V
G
R
F
E
L
K
V
M
R
Y
S
G
A
R
G
T
V
I
V
P
Y
W
T
E
N
D
T
A
T
E
S
K
-
D
Y
E
G
A
R
G
E
L
V
F
E
N
N
E
S
E
K
F
I
D
L
F
I
L
E
E
S
S
Y
E
K
D
V
S
F
K
V
H
I
G
E
P
R
L
A
----
P
D
D
G
L
A
--
A
K
I
K
E
V
E
--
K
K
P
V
Q
D
L
T
E
L
D
R
I
L
L
L
S
K
P
R
N
G
E
L
T
T
A
Y
V
R
I
R
E
S
Q
E
F
K
A
T
V
D
K
L
V
A
K
A
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
38
HHSearch
69.34
45%
-44
* C2 *
3E9T
-
?
A:
[3-112]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
R
M
Y
F
E
P
G
H
Y
T
V
M
E
N
C
G
E
F
E
V
R
V
V
R
R
G
D
I
-
S
T
Y
A
S
V
E
Y
E
T
Q
D
G
T
A
S
A
-
G
T
D
F
V
G
R
K
G
L
L
S
F
P
P
G
V
D
E
Q
R
F
R
I
E
V
I
D
D
D
V
F
E
E
D
E
C
F
Y
I
R
L
F
N
P
S
------------------------------
E
G
V
K
L
A
V
P
M
I
A
T
V
M
I
L
D
D
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
67.56
40%
-41
- C2 -
3EAD
1
?
A:
[5-115]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
R
M
Y
F
E
P
G
H
Y
T
V
M
E
N
C
G
E
F
E
V
R
V
V
-
R
R
G
D
I
S
T
Y
A
S
V
E
Y
E
T
Q
D
G
T
A
S
A
-
G
T
D
F
V
G
R
K
G
L
L
S
F
P
P
G
V
D
E
Q
R
F
R
I
E
V
I
D
D
D
V
F
E
E
D
E
C
F
Y
I
R
L
F
N
P
S
E
---
G
---------------------------
V
K
L
A
V
P
M
I
A
T
V
M
I
L
D
D
D
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26
PsiBlast_CBE
67.32
40%
-31
- C2 -
3EAD
1
?
C:
[5-116]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
R
M
Y
F
E
P
G
H
Y
T
V
M
E
N
C
G
E
F
E
V
R
V
V
-
R
R
G
D
I
S
T
Y
A
S
V
E
Y
E
T
Q
D
G
T
A
S
A
-
G
T
D
F
V
G
R
K
G
L
L
S
F
P
P
G
V
D
E
Q
R
F
R
I
E
V
I
D
D
D
V
F
E
E
D
E
C
F
Y
I
R
L
F
N
P
S
E
---
G
---------------------------
V
K
L
A
V
P
M
I
A
T
V
M
I
L
D
D
D
H
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------