@TOME V2.2
(Nov 2016)
Ref.
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : NCKX1_HUMAN: (2015-12-08 )
MGKLIRMGPQERWLLRTKRLHWSRLLFLLGMLIIGSTYQHLRRPRGLSSLWAAVSSHQPIKLASRDLSSEEMMMMSSSPSKPSSEMGGKMLVPQASVGSDEATLSMTVENIPSMPKRTAKMIPTTTKNNYSPTAAGTERRKEDTPTSSRTLTYYTSTSSRQIVKKYTPTPRGEMKSYSPTQVREKVKYTPSPRGRRVGTYVPSTFMTMETSHAITPRTTVKDSDITATYKILETNSLKRIMEETTPTTLKGMFDSTPTFLTHEVEANVLTSPRSVMEKNNLFPPRRVESNSSAHPWGLVGKSNPKTPQGTVLLHTPATSEGQVTISTMTGSSPAETKAFTAAWSLRNPSPRTSVSAIKTAPAIVWRLAKKPSTAPSTSTTPTVRAKLTMQVHHCVVVKPTPAMLTTPSPSLTTALLPEELSPSPSVLPPSLPDLHPKGEYPPDLFSVEERRQGWVVLHVFGMMYVFVALAIVCDEYFVPALGVITDKLQISEDVAGATFMAAGGSAPELFTSLIGVFISHSNVGIGTIVGSAVFNILFVIGTCSLFSREILNLTWWPLFRDVSFYILDLIMLILFFLDSLIAWWESLLLLLAYAFYVFTMKWNKHIEVWVKEQLSRRPVAKVMALEDLSKPGDGAIAVDELQDNKKLKLPSLLTRGSSSTSLHNSTIRSTIYQLMLHSLDPLREVRLAKEKEEESLNQGARAQPQAKAESKPEEEEPAKLPAVTVTPAPVPDIKGDQKENPGGQEDVAEAESTGEMPGEEGETAGEGETEEKSGGETQPEGEGETETQGKGEECEDENEAEGKGDNEGEDEGEIHAEDGEMKGNEGETESQELSAENHGEAKNDEKGVEDGGGSDGGDSEEEEEEEEEQEEEEEEEEQEEEEEEEEEEEEKGNEEPLSLDWPETRQKQAIYLFLLPIVFPLWLTVPDVRRQESRKFFVFTFLGSIMWIAMFSYLMVWWAHQVGETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPVPWLLFSLINGLQPVPVSSNGLFCAIVLLFLMLLFVISSIASCKWRMNKILGFTMFLLYFVFLIISVMLEDRIISCPVSV
Atome Classification :
(20 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120......--.130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430.......440.......450.......460..--.....470.......480.......490.......500.......510.......520-----.......530.......540.......550.......560.......570.......580.......590.......600----.......610.......620.......630.......640.......---------650.......660----........670.......680.......690.......700.......710-.......720.......730.......740.......750.......760.......770.......780.......790.......800.......810.......820.......830.......840.......850.......860.......870.......880.......890.......900.......910.......920.......930.......940---.......950......--.960....---...970.......980.......990.......1000......1010......1020......1030......1040......1050.......1060.--------.....1070......1080......1090......
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MGKLIRMG
P
Q
E
R
W
L
L
R
TKR
L
H
W
S
R
L
L
F
L
L
G
M
L
I
IG
S
T
Y
Q
H
L
RRPR
G
L
S
S
L
W
A
A
V
SSHQ
P
I
K
LASRDL
S
S
E
E
M
M
M
MSSSPSKP
S
S
EMGG
K
M
L
V
P
QASVGSDE
A
T
L
S
M
T
V
E
NIPSM
P
K
R
T
A
K
MIPTTTKN--NYSPTAAGTERRKEDTPTS
S
R
T
L
T
Y
Y
TSTS
S
R
Q
I
V
K
K
YTPTPRGEMKSY
S
P
T
Q
V
R
E
K
VKYTPSPRG
R
R
V
G
T
YVP
S
T
F
M
T
METSHAITPRTTVKDSD
I
T
A
T
Y
K
I
L
E
T
N
S
L
K
R
I
M
E
ETTP
T
T
L
K
GMFDSTP
T
F
L
T
H
EVEANVLTS
P
R
S
V
M
EKNNLFPPRRVESNSSAHPWGLVGKSNPKTPQ
G
T
V
L
L
HTPATSEG
Q
V
T
I
S
T
MTGSSPAET
K
A
F
T
A
A
W
SLRNPSPRT
S
V
S
A
IKT
A
P
A
I
V
W
R
LAKKPSTAPSTSTT
P
T
V
R
A
K
L
T
M
Q
V
H
H
C
V
V
VKPTP
A
M
L
TTPSPS
L
T
T
A
LL
P
E
ELSPSPSVLPPSLPDLHPKGEYPPDLF
S
V
E
E
RRQ
G
W
V
V
L
H
V
F
G
M
M
Y
--
V
F
V
A
L
A
I
V
C
D
E
Y
F
V
P
A
L
G
V
ITDK
L
Q
ISEDVAG
A
T
F
MAAGGS
A
P
E
L
F
T
S
L
I
G
V
F
ISHSN-----V
G
I
G
T
I
V
G
S
A
V
F
N
I
L
F
V
I
G
T
C
S
L
F
S
R
E
I
L
N
L
T
W
W
P
L
F
R
D
V
S
F
Y
I
L
D
L
I
M
L
I
L
F
F
L
D
S
L
I
A
W
W
E
S
L
L
L
L
L
A
Y
A
F
Y
V
F
T
MKW----NK
H
I
E
V
W
V
K
E
Q
LSRR
P
V
A
K
V
M
A
L
E
DLSKPGDG
A
I
A
V
DELQDNKKLKL---------
P
S
L
L
TRGSSSTS-----
L
H
N
S
T
I
R
S
T
I
Y
Q
L
M
L
HSL
D
P
L
R
E
V
R
L
A
K
E
K
E
E
E
S
L
NQGARAQPQAKAESKP-EEEEPAKL
P
A
V
T
VTPAPVPDIKGDQKENPGGQ
E
D
V
A
E
A
E
STGEMPGEEGETAGEGETEEKSGGETQPEGEGETETQGKGEECEDENEAEGKGDNEGEDEG
E
I
HAEDGEMKGNEGET
E
S
Q
ELSAENHGEAKNDEKGVEDGGGSDGGDS
E
E
E
E
E
E
E
E
E
Q
E
E
E
E
E
E
E
E
Q
E
E
E
E
E
E
E
E
E
E
E
EKGNEEPLSLDWPETRQ
K
Q
A
I
Y
L
F
L
L
P
I
V
F
P
L
WLTV
P
D
V
R
R
QESR
K
F
F
V
F
T
F
L
---
G
S
I
M
W
I
A
M
F
S
Y
L
M
V
W
W
--
A
H
Q
VGETI---GISEEI
M
G
L
T
I
L
AAGTS
I
P
D
L
I
T
S
V
I
V
A
RKGLG
D
M
A
VSSSVGS
N
I
F
D
I
T
VGL
P
V
P
W
L
L
F
S
L
INGLQPVPVSSN
G
L
F
C
A
I
V
L
L
F
L
-
M
L
L
F
V
I
S
S
I
A
S
C
K
W
--------
R
M
N
K
I
L
G
F
T
M
F
L
L
Y
F
V
F
L
I
I
S
V
M
L
EDRIISCPVSV
27
Fugue
73.35
18%
-50
- C2 -
3V5U
13
Y091_METJA
A:
[1-304]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
V
I
L
G
V
G
Y
F
L
--
L
G
L
I
L
L
Y
Y
G
S
D
W
F
V
L
G
S
E
R
I
A
R
H
F
N
V
S
N
F
V
I
G
A
T
V
M
A
I
G
T
S
L
P
E
I
L
T
S
A
Y
A
S
Y
M
H
A
P
G
-----
I
S
I
G
N
A
I
G
S
C
I
C
N
I
G
L
V
L
G
L
S
A
I
I
S
P
I
I
V
D
----
K
N
L
Q
K
N
I
L
V
Y
L
L
F
V
I
F
A
A
V
I
G
I
D
G
F
S
W
I
D
G
V
V
L
L
I
L
F
I
I
Y
L
R
W
T
V
K
N
G
SA
K
N
N
P
S
V
V
F
S
L
V
L
L
I
I
G
L
I
G
V
L
V
G
A
E
L
F
V
D
G
A
K
K
I
A
L
A
L
D
I
S
D
K
V
I
G
F
T
L
V
A
F
G
T
S
L
P
E
L
M
V
S
L
A
A
A
K
R
NL
G
G
M
V
L
G
N
V
I
G
S
N
I
A
D
I
G
G
A
L
A
V
G
S
L
F
M
H
L
P
A
E
N
V
Q
M
A
V
L
V
I
M
S
L
L
L
Y
L
F
A
K
Y
S
K
I
G
R
W
Q
G
I
L
F
L
A
L
Y
I
I
A
I
A
S
L
R
M
G
G
G
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
HHSearch
64.90
15%
12
- C2 -
3JAC
-
?
A:
[-2137]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
F
F
H
D
I
L
H
T
K
Y
R
A
--
A
T
D
V
Y
A
L
M
F
L
ADI
V
D
I
I
I
I
I
F
G
F
W
A
F
G
K
H
SA
A
T
D
I
A
S
S
L
SDD
Q
V
P
Q
A
F
L
F
M
L
L
V
Q
F
G
T
M
V
I
D
R
A
L
Y
-----------
L
R
K
T
V
L
G
K
L
A
F
Q
V
V
L
V
V
A
I
H
I
W
M
F
F
I
L
P
A
V
T
E
R
M
F
S
Q
N
A
V
--
A
Q
L
W
Y
F
V
K
C
I
Y
F
A
L
S
A
Y
Q
I
R
C
G
YPTRILGN
F
L
T
K
K
Y
N
H
L
N
L
F
L
F
Q
G
F
R
L
V
P
F
L
V
E
L
R
A
V
------
17
HHSearch
47.37
26%
-70
- C2 -
3V5U
10
Y091_METJA
A:
[165-304]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
V
L
L
I
---
I
G
L
I
G
V
L
V
G
A
E
L
F
V
D
G
--
A
K
K
I
A
L
A
L
---
D
I
S
D
K
V
I
G
F
T
L
V
A
F
G
T
S
L
P
E
L
M
V
S
L
A
A
A
K
R
N
L
G
G
M
V
L
G
N
V
I
G
S
N
I
A
D
I
G
G
A
L
A
V
G
S
L
F
M
H
L
-------
P
A
E
N
----
V
Q
M
A
V
L
V
I
-
M
S
L
L
L
Y
--
L
F
A
K
Y
S
--------
K
I
G
R
W
Q
G
I
L
F
L
A
L
Y
I
I
A
I
A
S
L
R
M
G
G
G
---------
18
HHSearch
47.17
27%
-37
- C2 -
3V5U
10
Y091_METJA
A:
[170-303]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
G
L
I
G
V
L
V
G
A
E
L
F
V
D
G
A
K
K
I
A
L
A
L
D
I
S
D
K
V
I
G
F
T
L
V
A
F
G
T
S
L
P
E
L
M
V
S
L
A
A
A
K
R
N
L
G
G
-----
M
V
L
G
N
V
I
G
S
N
I
A
D
I
G
G
A
L
A
V
G
S
L
F
M
H
--
L
P
A
E
----
N
V
Q
M
A
V
L
V
I
M
S
L
L
L
Y
L
F
A
K
Y
S
K
I
G
R
W
Q
G
I
L
F
L
A
L
Y
I
I
A
I
A
S
L
R
M
----
G
G
G
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
32
Fugue
46.93
24%
293
- C2 -
5BS7
-
?
E:
[36-105]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
D
E
G
E
P
Q
E
E
I
S
K
H
I
R
E
I
F
G
Y
D
R
K
K
Y
K
D
E
S
D
Y
A
L
R
Y
M
E
S
S
W
K
E
Q
Q
K
E
E
A
K
S
L
R
L
G
M
Q
E
D
L
E
E
M
R
R
E
E
E
E
M
Q
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
44.95
21%
134
- C3 -
3LZQ
-
?
A:
[67-158]
------------------------------------------------------------------------------------------------------
T
I
A
Y
E
L
K
N
T
D
T
G
A
I
K
R
G
T
L
M
P
M
V
A
D
D
G
P
H
Y
G
A
N
I
A
M
E
K
D
K
K
G
G
F
G
V
G
N
Y
E
L
T
F
Y
I
S
N
P
E
K
Q
G
F
G
R
H
V
D
E
E
T
G
V
G
K
W
F
E
P
F
K
V
D
Y
K
F
K
Y
T
G
T
P
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
44.45
21%
140
- C3 -
3LZL
-
?
A:
[67-158]
------------------------------------------------------------------------------------------------------
T
I
A
Y
E
L
K
N
T
D
T
G
A
I
K
R
G
T
L
M
P
M
V
A
D
D
G
P
H
Y
G
A
N
I
A
M
E
K
D
K
K
G
G
F
G
V
G
N
Y
E
L
T
F
Y
I
S
N
P
E
K
Q
G
F
G
R
H
V
D
E
E
T
G
V
G
K
W
F
E
P
F
K
V
D
Y
K
F
K
Y
T
G
T
P
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
44.43
21%
140
- C3 -
3LZP
-
?
A:
[67-159]
------------------------------------------------------------------------------------------------------
T
I
A
Y
E
L
K
N
T
D
T
G
A
I
K
R
G
T
L
M
P
M
V
A
D
D
G
P
H
Y
G
A
N
I
A
M
E
K
D
K
K
G
G
F
G
V
G
N
Y
E
L
T
F
Y
I
S
N
P
E
K
Q
G
F
G
R
H
V
D
E
E
T
G
V
G
K
W
F
E
P
F
K
V
D
Y
K
F
K
Y
T
G
T
P
K
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
PsiBlast_PDB
44.39
32%
-57
- C2 -
4MT1
-
?
A:
[860-954]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
S
E
E
A
K
G
G
S
Q
T
L
I
L
Y
G
L
A
V
A
A
V
F
L
V
L
A
A
L
Y
E
S
W
S
I
P
-
L
A
V
I
---
L
V
I
P
L
G
L
I
G
A
---
A
A
G
V
T
G
R
N
L
F
E
G
L
L
G
S
V
P
S
F
A
N
D
I
Y
F
Q
V
G
F
V
T
V
M
G
L
S
A
K
N
A
I
L
I
I
E
F
A
K
D
L
Q
A
Q
G
K
S
A
V
E
A
A
L
E
A
A
R
L
R
F
R
P
I
I
M
T
S
F
A
F
I
L
G
V
V
P
L
Y
I
A
A
G
A
S
S
A
S
Q
R
A
I
G
T
T
V
F
W
----
G
M
L
V
G
T
L
L
S
V
F
L
V
P
L
F
Y
V
V
V
R
K
F
F
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
44.38
21%
134
- C3 -
3LZR
-
?
A:
[67-159]
------------------------------------------------------------------------------------------------------
T
I
A
Y
E
L
K
N
T
D
T
G
A
I
K
R
G
T
L
M
P
M
V
A
D
D
G
P
H
Y
G
A
N
I
A
M
E
K
D
K
K
G
G
F
G
V
G
N
Y
E
L
T
F
Y
I
S
N
P
E
K
Q
G
F
G
R
H
V
D
E
E
T
G
V
G
K
W
F
E
P
F
K
V
D
Y
K
F
K
Y
T
G
T
P
K
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
44.05
21%
138
- C3 -
3LZN
-
?
A:
[67-159]
------------------------------------------------------------------------------------------------------
T
I
A
Y
E
L
K
N
T
D
T
G
A
I
K
R
G
T
L
M
P
M
V
A
D
D
G
P
H
Y
G
A
N
I
A
M
E
K
D
K
K
G
G
F
G
V
G
N
Y
E
L
T
F
Y
I
S
N
P
E
K
Q
G
F
G
R
H
V
D
E
E
T
G
V
G
K
W
F
E
P
F
K
V
D
Y
K
F
K
Y
T
G
T
P
K
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
43.78
21%
140
* C3 *
3LZO
-
?
A:
[67-159]
------------------------------------------------------------------------------------------------------
T
I
A
Y
E
L
K
N
T
D
T
G
A
I
K
R
G
T
L
M
P
M
V
A
D
D
G
P
H
Y
G
A
N
I
A
M
E
K
D
K
K
G
G
F
G
V
G
N
Y
E
L
T
F
Y
I
S
N
P
E
K
Q
G
F
G
R
H
V
D
E
E
T
G
V
G
K
W
F
E
P
F
K
V
D
Y
K
F
K
Y
T
G
T
P
K
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
33
Fugue
41.28
16%
278
- C2 -
3KXE
-
PARD1_CAUCR
C:
[5-79]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
T
S
V
V
L
G
D
H
F
Q
A
F
I
D
S
Q
V
A
D
G
R
Y
G
S
A
S
E
V
I
R
A
G
L
R
L
L
E
E
N
E
A
K
L
A
A
L
R
A
A
L
I
E
G
E
E
S
G
F
I
E
D
F
D
F
D
A
F
I
E
E
R
S
R
A
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
PsiBlast_PDB
40.60
23%
260
- C2 -
4DVY
-
CAGA_HELPY
P:
[591-664]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
K
A
L
N
F
N
K
A
V
A
E
A
K
S
T
--
G
N
Y
D
E
V
K
K
A
Q
K
D
L
E
K
S
L
R
K
R
E
H
L
E
K
E
V
E
K
K
L
E
S
K
S
---
N
K
M
E
A
K
A
Q
A
N
S
Q
K
D
E
I
F
A
L
I
N
K
E
A
N
R
D
A
R
A
I
A
Y
T
Q
N
L
K
G
I
K
R
E
L
S
D
K
L
---
E
K
I
S
K
D
L
K
D
F
S
K
S
F
D
E
--
F
K
E
E
T
L
K
A
---
L
K
G
S
V
K
D
L
G
I
N
P
E
W
I
S
K
V
E
N
L
N
A
A
L
N
E
F
K
N
F
S
K
V
T
Q
A
K
S
D
L
E
N
S
V
K
D
V
I
I
N
Q
K
V
T
D
K
V
D
N
L
N
Q
A
V
S
V
A
K
A
M
G
D
F
S
R
V
E
Q
V
L
A
D
L
-
K
N
F
S
K
E
Q
L
A
------------------------------------------------
35
Fugue
40.22
33%
420
* C2 *
3A1Q
-
UIMC1_MOUSE
C:
[76-120]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
P
L
G
S
E
E
E
Q
F
A
L
A
L
K
M
S
E
Q
E
A
R
E
V
N
N
Q
E
E
K
E
E
E
L
L
R
K
A
I
A
E
S
L
N
S
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
40.02
31%
19
- C2 -
3V5U
7
Y091_METJA
A:
[181-274]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
F
V
D
G
--
A
K
K
I
A
L
A
L
---
D
I
S
D
K
V
I
G
F
T
L
V
A
F
G
T
S
L
P
E
L
M
V
S
L
A
A
A
K
R
N
L
G
G
M
V
L
G
N
V
I
G
S
N
I
A
D
I
G
G
A
L
A
V
G
S
L
F
M
H
L
-------
P
A
E
N
V
Q
M
A
V
L
V
I
M
S
L
L
-
L
Y
L
F
A
K
Y
S
K
I
G
R
W
Q
--------
G
I
L
F
L
A
L
Y
I
I
A
I
A
S
L
R
M
G
G
G
---------------
14
PsiBlast_PDB
39.57
23%
312
- C2 -
4DVZ
-
CAGA_HELPY
A:
[591-664]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
K
A
L
N
F
N
K
A
V
A
E
A
K
S
T
--
G
N
Y
D
E
V
K
K
A
Q
K
D
L
E
K
S
L
R
K
R
E
H
L
E
K
E
V
E
K
K
L
E
S
K
S
G
N
K
-----
K
A
Q
A
N
S
Q
K
D
E
I
F
A
L
I
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
39.50
31%
28
- C2 -
3V5S
-
Y091_METJA
A:
[181-274]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
F
V
D
G
--
A
K
K
I
A
L
A
L
---
D
I
S
D
K
V
I
G
F
T
L
V
A
F
G
T
S
L
P
E
L
M
V
S
L
A
A
A
K
R
N
L
G
G
M
V
L
G
N
V
I
G
S
N
I
A
D
I
G
G
A
L
A
V
G
S
L
F
M
H
L
-------
P
A
E
N
V
Q
M
A
V
L
V
I
M
S
L
L
-
L
Y
L
F
A
K
Y
S
K
I
G
R
W
Q
--------
G
I
L
F
L
A
L
Y
I
I
A
I
A
S
L
R
M
------------------
4
PsiBlast_PDB
39.30
29%
15
- C2 -
4KJS
-
CHAA_BACSU
A:
[202-280]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
G
K
V
A
T
I
V
L
F
---
A
A
T
I
V
V
A
Y
I
S
E
N
L
V
H
T
--
F
H
S
V
A
E
Q
F
---
G
W
S
E
L
F
I
G
V
I
I
V
A
I
V
G
N
A
A
E
H
A
S
A
I
I
M
A
F
K
N
K
M
D
I
A
V
E
I
A
V
G
S
T
L
Q
I
A
M
F
V
A
P
V
L
V
I
C
S
I
F
F
P
T
S
M
P
L
V
F
T
L
P
E
L
V
A
M
V
S
A
V
L
L
-
M
I
A
I
S
N
D
G
D
S
N
W
F
E
--------
G
A
T
L
L
A
A
Y
V
I
M
A
I
G
F
F
L
L
-----------------
29
Fugue
38.99
25%
433
- C2 -
2K6I
-
Y223_METJA
A:
[1-47]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
G
V
S
V
M
E
A
I
K
E
V
K
L
A
E
E
Q
A
V
K
E
I
E
E
A
K
N
R
A
E
Q
I
K
A
E
A
I
E
E
A
K
K
L
I
A
C
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------