@TOME V2.2
(Nov 2016)
Ref.
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : NCKX2_HUMAN: (2015-12-08 )
MDLQQSTTITSLEKWCLDESLSGCRRHYSVKKKLKLIRVLGLFMGLVAISTVSFSISAFSETDTQSTGEASVVSGPRVAQGYHQRTLLDLNDKILDYTPQPPLSKEGESENSTDHAQGDYPKDIFSLEERRKGAIILHVIGMIYMFIALAIVCDEFFVPSLTVITEKLGISDDVAGATFMAAGGSAPELFTSLIGVFIAHSNVGIGTIVGSAVFNILFVIGMCALFSREILNLTWWPLFRDVSFYIVDLIMLIIFFLDNVIMWWESLLLLTAYFCYVVFMKFNVQVEKWVKQMINRNKVVKVTAPEAQAKPSAARDKDEPTLPAKPRLQRGGSSASLHNSLMRNSIFQLMIHTLDPLAEELGSYGKLKYYDTMTEEGRFREKASILHKIAKKKCHVDENERQNGAANHVEKIELPNSTSTDVEMTPSSDASEPVQNGNLSHNIEGAEAQTADEEEDQPLSLAWPSETRKQVTFLIVFPIVFPLWITLPDVRKPSSRKFFPITFFGSITWIAVFSYLMVWWAHQVGETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPLPWLLYTVIHRFQPVAVSSNGLFCAIVLLFIMLLFVILSIALCKWRMNKILGFIMFGLYFVFLVVSVLLEDRILTCPVSI
Atome Classification :
(20 SA)
.........10........20..-......-30........40........50........60........70........80........90........100.......110.......120.......130..--.....140.......150.......160.......170.......180......--------.190.......200-----.......210.......220.......230.......240.......250.......260.......270.......280-------.......290.......300.......310......-.320.......330.......340..-------.....350.......360.......370.......380.......390...-....400.......410.......420.......430.......440.......450.......460.......470.......480.......490.......500.......510.......520.......530.......540.......550.......560.......570.......580.......590.......600.......610.......620.......630.......640.......650.......660
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MDLQQS
T
T
I
T
S
L
E
K
W
C
L
D
E
S
L
S
G
-
C
R
R
H
Y
S
-
V
K
K
K
L
K
L
I
R
V
L
G
L
F
M
G
L
V
A
I
S
T
V
S
F
S
I
S
AFSETDTQSTGEASVVSGPRVAQGYHQ
R
T
L
LDLNDKILDYTPQPPLSKEGESENSTDHAQGDY
P
K
D
I
F
S
L
E
E
RRK
G
A
--
I
I
L
H
V
I
G
M
I
Y
M
F
I
A
L
A
I
V
C
D
E
FFV
P
S
L
T
V
I
T
E
KLGISDDVAG
A
T
F
MAAGGS
A
P
E
--------
L
F
T
S
L
I
G
V
F
I
AHSN-----V
G
I
G
T
I
V
G
S
A
V
F
N
I
L
F
V
I
G
M
C
A
L
F
S
R
E
I
L
N
L
T
W
W
P
L
F
R
D
V
S
F
Y
I
V
D
L
I
M
L
I
I
F
F
L
D
N
V
I
M
W
W
E
S
L
L
L
L
T
A
Y
F
C
Y
V
V
F
M
KF-------N
V
Q
V
E
K
W
V
K
Q
M
INRN
K
V
V
K
V
TAPEAQAKPSAARDKD-EPTLPAKP
R
L
QRGGSS
A
S
L
H
N
S
L
M
R
N
-------
S
I
F
Q
L
M
I
H
T
L
D
P
L
A
E
E
L
GSYGK
L
K
Y
Y
DTMTEEGR
F
R
E
K
A
S
I
L
H
K
I
A
K
K
KCH-VDENERQNGAANH
V
E
K
I
ELPNSTST
D
V
E
MTPSSDASEPVQNGNLSHNIEGAEAQTADEEEDQ
P
L
S
L
AWPSETR
K
Q
V
T
F
L
I
V
F
P
I
V
F
P
L
WITLPDVRKPSSR
K
F
F
P
I
T
FFG
S
I
T
W
I
A
V
F
S
Y
L
M
V
W
W
A
H
Q
VGETIGISEEI
M
G
L
T
I
L
AAGTS
I
P
D
L
I
T
S
V
I
V
A
RKGLG
D
M
A
VSSSVGS
N
I
F
D
I
T
VGLP
L
P
W
L
L
Y
T
V
I
H
RFQ
P
V
A
VSSN
G
L
F
C
A
I
V
L
L
F
I
M
L
L
F
V
I
L
S
I
A
L
C
K
W
R
M
N
K
I
L
G
F
I
M
F
G
L
Y
F
V
F
L
V
V
S
V
L
LEDRILTCPVSI
10
HHSearch
86.04
25%
-141
- C2 -
3V5U
13
Y091_METJA
A:
[16-304]
---------------------------------------------------------------------------------------------------------------------------------------------------------
L
Y
Y
G
S
D
W
F
V
L
G
S
E
R
I
A
R
H
F
N
V
S
N
F
V
I
G
A
T
V
M
A
I
G
T
S
L
P
E
--------
I
L
T
S
A
Y
A
S
Y
M
H
A
P
G
-----
I
S
I
G
N
A
I
G
S
C
I
C
N
I
G
L
V
L
G
L
S
A
I
I
S
P
--
I
I
V
D
K
-
N
L
Q
K
N
I
L
V
Y
L
L
F
V
I
F
A
A
-
V
I
G
I
D
G
F
S
W
I
D
G
V
V
L
L
I
L
F
I
I
Y
L
R
W
T
V
K
-------
N
G
S
A
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
N
N
P
-------
S
V
-----------------------------
V
F
S
L
V
L
L
I
I
G
L
I
G
V
L
V
G
A
E
L
F
V
D
G
A
K
K
I
A
L
A
L
D
I
S
D
K
V
I
G
F
T
L
V
A
F
G
T
S
L
P
E
L
M
V
S
L
A
A
A
K
R
N
L
G
G
M
V
L
G
N
V
I
G
S
N
I
A
D
I
G
G
A
L
A
V
G
S
L
F
M
H
-------
L
P
A
E
N
V
Q
---
M
A
V
L
V
-
I
M
S
L
L
L
-
Y
-
L
F
A
K
Y
S
K
I
G
R
W
Q
G
I
L
F
L
A
L
Y
I
I
A
I
A
S
L
R
M
G
G
G
---------
16
Fugue
81.11
17%
-61
- C2 -
3V5U
13
Y091_METJA
A:
[1-304]
------------------------------------------------------------------------------------------------------------------------------------------
M
V
I
L
G
V
G
Y
F
L
L
G
L
I
L
L
Y
Y
G
S
D
W
F
V
L
G
S
E
R
I
A
R
H
F
N
V
S
N
F
V
I
G
A
T
V
M
A
I
G
T
S
L
P
E
--------
I
L
T
S
A
Y
A
S
Y
M
H
A
P
G
-----
I
S
I
G
N
A
I
G
S
C
I
C
N
I
G
L
V
L
G
L
S
A
I
I
S
P
I
I
V
D
----
K
N
L
Q
K
N
I
L
V
Y
L
L
F
V
I
F
A
A
V
I
G
I
D
G
F
S
W
I
D
G
V
V
L
L
I
L
F
I
I
Y
L
R
W
T
V
K
N
G
SAKNN
P
S
V
V
F
S
L
V
L
L
I
I
G
L
I
G
V
L
V
G
A
E
L
F
V
D
G
A
K
K
I
A
L
A
L
D
I
S
D
K
V
I
G
F
T
L
V
A
F
G
T
S
L
P
E
L
M
V
S
L
A
A
A
K
R
NL
G
G
M
V
L
G
N
V
I
G
S
N
I
A
D
I
G
G
A
L
A
V
G
S
L
F
M
H
L
P
A
E
N
V
Q
M
A
V
L
V
I
M
S
L
L
L
Y
L
F
A
K
Y
S
K
-
I
G
R
W
Q
G
I
L
F
L
A
L
Y
I
I
A
I
A
S
L
R
M
G
G
G
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
Fugue
51.18
12%
80
- C2 -
3THF
-
SHRM_DROME
A:
[1396-1570]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
-------
N
L
I
K
Q
K
M
D
E
L
I
K
H
L
N
Q
K
I
V
S
L
K
R
E
Q
Q
T
I
S
E
E
C
S
A
N
D
-
R
L
G
Q
D
L
F
A
K
L
A
E
K
V
R
P
S
E
A
S
K
F
R
T
H
V
-------
D
A
V
G
N
I
T
S
L
L
L
S
L
S
E
R
L
A
Q
T
E
S
S
L
E
T
R
Q
Q
E
R
G
A
L
E
S
K
R
D
L
L
Y
E
Q
M
E
E
A
Q
R
L
-
K
S
D
I
E
R
R
G
V
S
I
A
G
L
L
A
K
N
L
S
A
D
M
C
A
D
Y
D
Y
F
I
N
M
K
A
K
L
I
A
D
A
R
D
L
A
V
R
I
K
G
S
E
E
Q
L
S
S
L
S
D
A
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
HHSearch
47.63
26%
-65
- C2 -
3V5U
10
Y091_METJA
A:
[175-303]
---------------------------------------------------------------------------------------------------------------------------------------------------------
V
L
V
G
A
E
L
F
V
D
G
A
K
K
I
A
L
A
L
D
I
S
D
K
V
I
G
F
T
L
V
A
F
G
T
S
L
P
E
--------
L
M
V
S
L
A
A
A
K
R
N
L
G
G
-----
M
V
L
G
N
V
I
G
S
N
I
A
D
I
G
G
A
L
A
V
G
S
L
F
M
H
--
L
P
A
E
----
N
V
Q
M
A
V
L
V
I
M
S
L
L
L
Y
L
F
A
K
Y
S
K
I
G
R
W
Q
G
I
L
F
L
A
L
Y
I
I
A
I
A
S
L
R
M
-------
G
G
G
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
44.58
25%
-52
- C3 -
4MT1
-
?
A:
[860-954]
-------------------------------------------------------------------------------------------------------------------------------
S
S
E
E
A
K
G
G
S
Q
T
L
I
L
Y
G
L
A
V
A
A
V
F
L
V
L
A
A
L
Y
E
S
W
S
I
P
L
A
V
I
L
V
I
P
L
G
L
I
G
A
A
A
G
V
T
-------
G
R
N
--------
L
F
E
G
L
L
G
S
V
P
S
F
A
N
D
I
Y
F
Q
V
G
F
V
T
V
M
G
L
S
A
K
N
A
I
L
I
I
E
F
A
K
D
L
Q
A
Q
G
K
S
A
V
E
A
A
L
E
A
A
R
L
R
F
R
P
I
I
M
T
S
F
A
F
I
L
G
V
V
P
L
Y
I
A
A
G
A
S
S
A
S
Q
R
A
I
G
T
T
V
F
W
-------
G
M
L
V
G
T
L
L
S
V
F
L
V
P
L
F
Y
V
V
V
R
K
F
F
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
44.48
31%
-19
- C3 -
4KJS
-
CHAA_BACSU
A:
[202-280]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
G
K
V
A
T
I
V
L
F
A
A
T
I
V
V
A
Y
I
S
E
N
L
V
H
T
F
H
S
V
A
E
Q
F
G
W
S
E
L
F
I
G
V
I
I
V
A
I
V
G
N
A
A
E
H
A
S
A
I
I
M
A
F
K
N
K
M
D
I
A
V
E
I
A
V
G
S
T
L
Q
I
A
M
F
V
A
P
V
L
V
I
C
S
I
F
F
P
T
S
M
P
L
V
F
T
L
P
E
L
V
A
M
V
S
A
V
L
L
M
I
A
I
S
N
D
G
D
S
N
W
F
E
G
A
T
L
L
A
A
Y
V
I
M
A
I
G
F
F
L
L
-----------------
25
Fugue
42.77
12%
83
- C2 -
1EZJ
-
A:
[2-115]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
N
T
S
S
M
-
K
E
M
A
T
L
L
T
S
L
G
V
I
Q
S
A
Q
E
F
E
S
S
R
D
A
S
-------
Y
V
F
A
R
R
A
L
K
S
A
N
Y
A
E
M
T
F
N
V
C
G
L
I
L
S
A
E
K
S
S
A
R
K
V
D
E
N
K
Q
L
L
K
Q
I
Q
E
S
V
E
S
-
F
R
D
I
Y
K
R
F
S
E
Y
Q
K
E
Q
N
S
L
L
M
S
N
L
S
T
L
H
I
I
T
D
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
Fugue
42.27
8%
170
- C2 -
2QA7
-
HIP1_HUMAN
A:
[371-469]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
E
K
D
H
L
I
E
R
L
Y
R
E
I
S
G
L
K
A
Q
-
L
E
N
M
K
T
E
S
Q
R
V
V
L
Q
L
K
G
H
V
S
E
L
E
A
D
L
A
E
Q
Q
H
L
R
Q
Q
A
A
D
D
C
E
F
L
R
A
E
L
D
E
L
R
R
Q
R
E
D
T
E
K
A
Q
R
S
L
S
E
I
E
R
K
A
Q
A
N
E
Q
R
Y
S
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
Fugue
42.12
11%
127
* C2 *
2JEE
-
ZAPB_ECOLI
A:
[3-80]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
S
L
E
V
-------
F
E
K
L
E
A
K
V
Q
Q
A
I
D
T
I
T
L
L
Q
M
E
I
E
E
L
K
E
K
N
N
S
L
S
Q
E
V
-
Q
N
A
Q
H
Q
R
E
E
L
E
R
E
N
N
H
L
K
E
Q
Q
N
G
W
Q
E
-------
R
L
Q
A
L
L
G
R
M
E
E
V
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
41.64
31%
-4
- C3 -
4KJR
-
CHAA_BACSU
A:
[202-280]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
G
K
V
A
T
I
V
L
F
A
A
T
I
V
V
A
Y
I
S
E
N
L
V
H
T
F
H
S
V
A
E
Q
F
G
W
S
E
L
F
I
G
V
I
I
V
A
I
V
G
N
A
A
E
H
A
S
A
I
I
M
A
F
K
N
K
M
D
I
A
V
E
I
A
V
G
S
T
L
Q
I
A
M
F
V
A
P
V
L
V
I
C
S
I
F
F
P
T
S
M
P
L
V
F
T
L
P
E
L
V
A
M
V
S
A
V
L
L
M
I
A
I
S
N
D
G
D
S
N
W
F
E
G
A
T
L
L
A
A
Y
V
I
M
A
I
G
F
F
L
L
-----------------
20
Fugue
41.22
10%
77
- C2 -
2K21
-
KCNE1_HUMAN
A:
[1-129]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
I
L
S
N
T
T
A
V
T
P
F
L
T
K
L
W
Q
E
T
V
Q
Q
G
G
N
-
M
S
G
L
A
R
R
S
P
R
S
G
D
G
K
L
E
A
L
Y
V
L
M
V
L
G
-------
F
F
G
F
F
T
L
G
I
M
L
S
Y
I
R
S
K
K
L
E
H
S
N
D
P
F
N
V
Y
I
E
S
D
A
W
Q
E
K
D
K
A
Y
V
Q
A
R
V
L
E
S
Y
-
K
S
C
Y
V
V
E
N
H
L
A
I
E
Q
P
N
T
H
L
P
E
T
K
P
S
P
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
Fugue
40.20
6%
160
- C2 -
2CLY
-
AT5F1_BOVIN
A:
[79-183]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
E
F
A
D
K
L
N
E
Q
K
I
A
Q
L
E
E
V
K
Q
A
S
I
K
Q
I
Q
D
A
-
I
D
M
E
K
S
Q
Q
A
L
V
Q
K
R
H
Y
L
F
D
V
Q
R
N
N
I
A
M
A
L
E
V
T
Y
R
E
R
L
H
R
V
Y
R
E
V
K
N
R
L
D
Y
H
I
S
V
Q
N
M
M
R
Q
K
E
Q
E
H
M
I
N
W
V
E
K
R
V
V
Q
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
Fugue
39.89
7%
99
- C2 -
4CPC
-
SYCP3_HUMAN
A:
[18-160]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
N
-
K
A
L
L
A
K
R
K
R
L
E
M
Y
T
K
A
S
L
K
T
S
N
Q
K
I
E
-------
H
V
W
K
T
Q
Q
D
Q
R
Q
K
L
N
Q
E
Y
S
Q
Q
F
L
T
L
F
Q
Q
W
D
L
D
M
Q
K
A
E
E
Q
E
E
K
I
L
N
M
F
R
Q
Q
Q
K
I
L
Q
Q
S
R
I
V
Q
S
Q
R
L
K
T
I
K
Q
L
Y
E
Q
F
I
K
S
M
E
E
L
E
K
N
H
D
N
L
L
T
G
A
Q
N
E
F
K
K
E
M
A
M
L
Q
K
K
I
M
M
E
T
Q
Q
Q
E
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
HHSearch
37.82
21%
401
- C3 -
2YKR
-
RS18_ECOLI
R:
[42-67]
-------------------
R
I
T
G
T
R
A
K
Y
Q
R
Q
L
A
R
A
I
K
R
A
R
Y
L
S
L
L
P
Y
T
D
R
H
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
37.49
26%
-3
- C3 -
4K1C
1
VCX1_YEAST
A:
[260-332]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
I
L
L
G
T
T
V
I
I
S
F
C
A
D
F
L
V
G
T
I
D
N
V
V
E
S
T
G
L
S
K
T
F
I
G
L
I
V
I
P
I
V
G
N
A
A
E
H
V
T
S
V
L
V
A
M
K
D
K
M
D
L
A
L
G
V
A
I
G
S
S
L
Q
V
A
L
F
V
T
P
F
M
V
L
V
G
W
M
I
D
V
P
M
T
L
N
F
S
T
F
E
T
A
T
L
F
I
A
V
F
L
S
N
Y
L
I
L
D
G
E
S
N
W
L
E
G
V
M
S
L
A
M
Y
I
L
I
A
M
A
F
F
Y
Y
P
D
E
--------------
2
PsiBlast_PDB
36.13
39%
52
- C3 -
3V5U
4
Y091_METJA
A:
[181-241]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
F
V
D
G
A
K
K
I
A
L
A
L
D
I
S
D
K
V
I
G
F
T
L
V
A
F
G
T
S
L
P
E
L
M
V
S
L
A
A
A
K
R
N
L
G
G
M
V
L
G
N
V
I
G
S
N
I
A
D
I
G
G
A
L
A
V
G
S
L
F
M
H
L
P
A
E
N
V
Q
M
A
V
L
V
I
M
S
L
L
L
Y
L
F
A
K
Y
S
K
I
G
R
W
Q
G
I
L
F
L
A
L
Y
I
I
A
I
A
S
L
R
M
G
G
G
----------------------
1
PsiBlast_PDB
34.99
39%
51
- C3 -
3V5S
-
Y091_METJA
A:
[181-241]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
F
V
D
G
A
K
K
I
A
L
A
L
D
I
S
D
K
V
I
G
F
T
L
V
A
F
G
T
S
L
P
E
L
M
V
S
L
A
A
A
K
R
N
L
G
G
M
V
L
G
N
V
I
G
S
N
I
A
D
I
G
G
A
L
A
V
G
S
L
F
M
H
L
P
A
E
N
V
Q
M
A
V
L
V
I
M
S
L
L
L
Y
L
F
A
K
Y
S
K
I
G
R
W
Q
G
I
L
F
L
A
L
Y
I
I
A
I
A
S
L
R
M
-------------------------
9
PsiBlast_PDB
31.89
28%
-50
* C4 *
2Y4F
-
EFEB_ECOLI
A:
[69-133]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
L
T
Q
G
G
A
A
P
E
TPNPRLPP
L
D
S
G
I
L
G
G
Y
I
A
P
D
N
-----
L
T
I
T
L
S
V
G
H
S
L
F
D
E
R
F
--
G
L
A
P
Q
M
P
K
K
L
Q
K
M
T
R
F
P
N
D
S
L
D
A
A
L
C
H
G
D
V
L
L
Q
I
C
A
N
T
Q
D
T
V
I
H
A
L
R
D
I
I
K
H
T
P
D
L
L
S
V
R
W
K
-------
R
E
G
F
I
S
D
H
A
A
R
S
K
G
K
E
T
P
I
N
L
L
G
F
K
D
G
T
A
N
P
D
S
Q
N
D
-
K
L
M
Q
K
V
V
W
V
T
A
D
Q
Q
E
P
A
W
T
I
G
G
S
Y
Q
A
-------
V
R
L
I
Q
F
R
V
E
F
W
D
R
T
P
L
K
E
Q
Q
T
I
F
G
R
D
K
Q
T
G
A
P
L
G
M
Q
H
E
H
D
V
P
D
Y
A
S
D
P
E
G
K
-
V
I
A
L
D
S
H
I
R
L
A
N
P
R
T
A
E
S
E
S
S
L
M
L
R
R
G
Y
S
Y
S
L
G
V
T
N
S
G
Q
L
D
M
G
L
L
F
V
C
Y
Q
H
D
L
E
K
G
F
L
T
V
Q
K
R
L
N
G
E
A
L
E
E
Y
V
K
P
I
G
G
G
Y
F
F
A
L
P
G
V
K
D
A
N
D
Y
F
G
S
A
L
L
R
V
---------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
31.25
28%
-53
- C4 -
2Y4E
1
EFEB_ECOLI
A:
[80-144]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
L
T
Q
G
G
A
A
P
E
TPNPRLPP
L
D
S
G
I
L
G
G
Y
I
A
P
D
N
-----
L
T
I
T
L
S
V
G
H
S
L
F
D
E
R
F
--
G
L
A
P
Q
M
P
K
K
L
Q
K
M
T
R
F
P
N
D
S
L
D
A
A
L
C
H
G
D
V
L
L
Q
I
C
A
N
T
Q
D
T
V
I
H
A
L
R
D
I
I
K
H
T
P
D
L
L
S
V
R
W
K
-------
R
E
G
F
I
S
D
H
A
A
R
S
K
G
K
E
T
P
I
N
L
L
G
F
K
D
G
T
A
N
P
D
S
Q
N
D
-
K
L
M
Q
K
V
V
W
V
T
A
D
Q
Q
E
P
A
W
T
I
G
G
S
Y
Q
A
-------
V
R
L
I
Q
F
R
V
E
F
W
D
R
T
P
L
K
E
Q
Q
T
I
F
G
R
D
K
Q
T
G
A
P
L
G
M
Q
H
E
H
D
V
P
D
Y
A
S
D
P
E
G
K
-
V
I
A
L
D
S
H
I
R
L
A
N
P
R
T
A
E
S
E
S
S
L
M
L
R
R
G
Y
S
Y
S
L
G
V
T
N
S
G
Q
L
D
M
G
L
L
F
V
C
Y
Q
H
D
L
E
K
G
F
L
T
V
Q
K
R
L
N
G
E
A
L
E
E
Y
V
K
P
I
G
G
G
Y
F
F
A
L
P
G
V
K
D
A
N
D
Y
F
G
S
A
L
L
R
V
---------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
31.06
28%
-52
- C4 -
2Y4D
3
EFEB_ECOLI
A:
[80-144]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
L
T
Q
G
G
A
A
P
E
TPNPRLPP
L
D
S
G
I
L
G
G
Y
I
A
P
D
N
-----
L
T
I
T
L
S
V
G
H
S
L
F
D
E
R
F
--
G
L
A
P
Q
M
P
K
K
L
Q
K
M
T
R
F
P
N
D
S
L
D
A
A
L
C
H
G
D
V
L
L
Q
I
C
A
N
T
Q
D
T
V
I
H
A
L
R
D
I
I
K
H
T
P
D
L
L
S
V
R
W
K
-------
R
E
G
F
I
S
D
H
A
A
R
S
K
G
K
E
T
P
I
N
L
L
G
F
K
D
G
T
A
N
P
D
S
Q
N
D
-
K
L
M
Q
K
V
V
W
V
T
A
D
Q
Q
E
P
A
W
T
I
G
G
S
Y
Q
A
-------
V
R
L
I
Q
F
R
V
E
F
W
D
R
T
P
L
K
E
Q
Q
T
I
F
G
R
D
K
Q
T
G
A
P
L
G
M
Q
H
E
H
D
V
P
D
Y
A
S
D
P
E
G
K
-
V
I
A
L
D
S
H
I
R
L
A
N
P
S
E
S
S
L
M
L
R
R
G
Y
S
Y
S
L
G
V
T
N
S
G
Q
L
D
M
G
L
L
F
V
C
Y
Q
H
D
L
E
K
G
F
L
T
V
Q
K
R
L
N
G
E
A
L
E
E
Y
V
K
P
I
G
G
G
Y
F
F
A
L
P
G
V
K
D
A
N
D
Y
F
G
S
A
L
L
R
V
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------