@TOME V2.2
(Nov 2016)
Ref.
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : NRAM2_HUMAN: (2015-12-08 )
MVLGPEQKMSDDSVSGDHGESASLGNINPAYSNPSLSQSPGDSEEYFATYFNEKISIPEEEYSCFSFRKLWAFTGPGFLMSIAYLDPGNIESDLQSGAVAGFKLLWILLLATLVGLLLQRLAARLGVVTGLHLAEVCHRQYPKVPRVILWLMVELAIIGSDMQEVIGSAIAINLLSVGRIPLWGGVLITIADTFVFLFLDKYGLRKLEAFFGFLITIMALTFGYEYVTVKPSQSQVLKGMFVPSCSGCRTPQIEQAVGIVGAVIMPHNMYLHSALVKSRQVNRNNKQEVREANKYFFIESCIALFVSFIINVFVVSVFAEAFFGKTNEQVVEVCTNTSSPHAGLFPKDNSTLAVDIYKGGVVLGCYFGPAALYIWAVGILAAGQSSTMTGTYSGQFVMEGFLNLKWSRFARVVLTRSIAIIPTLLVAVFQDVEHLTGMNDFLNVLQSLQLPFALIPILTFTSLRPVMSDFANGLGWRIAGGILVLIICSINMYFVVVYVRDLGHVALYVVAAVVSVAYLGFVFYLGWQCLIALGMSFLDCGHTCHLGLTAQPELYLLNTMDADSLVSR
Atome Classification :
(19 SA)
--.........--10........20........30........40....--....50........60-.........70....-....80........90........100--........110----...-..-----..120...-------....130.......140......-.-150.......160.....-------..170....---.--------.--.-180.-------......190.......200-......---.------.210.......220--.........230.......240.......250....-.-...260....--...270.......280.......290--.......300.......310.......320..-.....330.......340------------------.........350..-----------...---..360.......370.......-380.......390..------.....400--.........410.......420...-....430.......--..440......---.450.......460.......470.......480.......490-.......500.......510.........520.......530.......540.......550.......560......---------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
--MVLGPEQKM--SDDSVSGDHGESASLGNINPAYSNPSLSQSPG
D
S
E
E
--
Y
F
A
T
Y
F
NEKISI
P
E
E
--
E
Y
S
C
F
S
F
R
K
L
WAFTG-P
G
F
L
M
S
I
A
YLDPGN
I
E
S
D
L
Q
S
G
A
V
A
G
---
F
K
L
L
W
I
L
L
L
A
T
----
L
V
G
-
L
L
-----
L
Q
R
L
A
A
R
L
-------
G
V
V
T
G
L
H
L
A
E
V
C
H
R
QYPK
V
P
R
V
I
-
L
-
W
L
M
V
E
L
A
I
IG
S
D
M
Q
E
V
I
G
-------
S
A
I
A
I
N
L
L
S---V--------G--R-IPLW-------G
G
V
L
I
T
I
A
D
T
F
V
F
L
F
L
D
K
--YG
L
R
K
L
---
E
------
A
F
F
G
F
L
I
T
I
M
A
L
----
T
FG
Y
E
Y
V
T
VKP
S
Q
S
Q
V
L
K
G
M
FVPSCSGCRT-P
Q
I
E
Q
-
A
-
V
G
I
V
G
A
V
IMP--H
N
M
Y
L
H
S
A
L
V
K
S
RQVNRN
N
K
Q
E
V
R
E
A
--NKY
F
F
I
E
S
C
I
A
L
F
V
S
F
I
I
N
V
F
V
V
S
V
F
A
E
A
FFG-K
T
N
E
Q
V
V
E
V
CTNTSSP--------------------HAGLFPKDN
S
T
L
A
V
-----------
D
I
Y---KG
G
V
V
L
G
C
YFG
P
A
A
L
Y
I
W
A
V
G
I
-LAAGQSS
T
M
T
GTYS
G
------
Q
F
V
M
E
G
----
F
LNL
K
W
S
R
F
A
R
V
V
L
TR
S
I
A
I
I
P
T
L
L
-
V
A
V
F
Q
--
D
V
E
H
LTG--
M
N
D
F
L
N
V
L
Q
SL---QL
P
F
A
L
I
P
I
L
T
F
T
S
L
R
P
V
M
S
D
F
ANGL
G
W
R
IAG
G
I
L
V
L
I
I
CSI
N
M
-
Y
F
V
V
V
Y
V
R
D
L
G
H
V
A
L
Y
V
V
--
A
A
V
V
S
V
A
Y
L
G
F
V
F
Y
L
G
W
Q
C
L
I
A
L
G
M
S
F
L
DCGHTCHLGLTAQ
P
E
L
Y
L
L
NTM
D
A
D
S
LVSR---------------------
12
Fugue
92.99
38%
-113
- C4 -
4WGV
-
?
A:
[5-399]
------------------------------------------------------------------------------------------
V
G
Y
M
D
P
G
N
W
I
T
S
M
Q
G
G
A
Q
Y
G
---
Y
T
L
L
F
V
I
L
I
S
S
----
L
A
A
-
M
L
-----
L
Q
S
M
T
V
R
L
-------
G
I
A
T
G
K
D
L
A
Q
M
T
R
H
F
L
S
K
P
V
A
I
I
-
F
-
W
I
I
A
E
L
A
I
I
A
T
D
I
A
E
V
I
G
-------
S
A
I
A
L
D
L
I
F
---------------
G
-
I
P
L
I
-------
V
G
A
L
I
T
V
F
D
V
F
L
L
L
F
I
M
R
--
F
G
F
R
K
I
---
E
------
A
I
V
G
T
L
I
F
T
V
L
A
----
I
F
V
F
E
V
F
I
S
S
P
Q
L
T
D
I
L
N
G
F
V
P
H
K
E
I
V
T
N
Q
-
G
I
L
Y
I
-
A
-
L
G
I
I
G
A
T
I
M
P
--
H
N
L
Y
L
H
S
S
I
V
Q
S
R
K
Y
D
R
H
D
N
E
E
K
A
Q
A
--
I
K
Y
A
T
I
D
S
N
L
Q
L
S
I
A
F
V
V
N
C
L
L
L
T
L
G
A
A
L
F
F
G
-------------
T
K
T
N
--------------------
D
L
G
G
F
Y
D
L
Y
H
A
L
K
T
-----------
E
P
--------
V
L
G
A
T
L
G
G
V
M
S
T
L
F
A
V
A
L
-
L
A
S
G
Q
N
S
T
I
T
G
T
L
A
G
------
Q
I
V
M
E
G
----
F
L
R
L
S
I
P
N
W
L
R
R
L
I
T
R
S
L
A
V
I
P
V
I
I
-
C
L
I
I
F
KG
N
S
E
K
I
E
Q
--
L
L
V
F
S
Q
V
F
L
S
I
---
A
L
P
F
S
L
I
P
L
Q
L
A
T
S
N
K
K
L
M
G
P
F
I
N
K
T
W
V
N
I
I
S
W
T
L
I
V
I
L
S
G
L
N
V
-
Y
--------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
92.14
36%
-122
- C4 -
4WGV
-
?
A:
[5-399]
------------------------------------------------------------------------------------------
V
G
Y
M
D
P
G
N
W
I
T
S
M
Q
G
G
A
Q
Y
G
---
Y
T
L
L
F
V
I
L
I
S
S
----
L
A
A
-
M
L
-----
L
Q
S
M
T
V
R
L
-------
G
I
A
T
G
K
D
L
A
Q
M
T
R
H
F
L
S
K
P
V
A
I
I
-
F
-
W
I
I
A
E
L
A
I
I
A
T
D
I
A
E
V
I
G
-------
S
A
I
A
L
D
L
-----
I
--------
F
--
G
-
I
P
L
I
-------
V
G
A
L
I
T
V
F
D
V
F
L
L
L
F
I
M
R
--
F
G
F
R
K
I
---
E
------
A
I
V
G
T
L
I
F
T
V
L
A
----
I
F
V
F
E
V
F
I
S
S
P
Q
L
T
D
I
L
N
G
-
F
V
P
H
K
E
I
V
T
N
-
Q
G
I
L
Y
I
A
-
L
G
I
I
G
A
T
I
M
P
--
H
N
L
Y
L
H
S
S
I
V
Q
S
R
K
Y
D
R
H
D
N
E
E
K
A
Q
A
--
I
K
Y
A
T
I
D
S
N
L
Q
L
S
I
A
F
V
V
N
C
L
L
L
T
L
G
A
A
L
F
F
G
T
K
T
N
D
L
--------------------------------
G
G
F
Y
--------------------
D
L
Y
H
A
L
K
T
E
P
V
L
G
A
T
L
G
G
V
M
S
T
L
F
A
V
A
L
-
L
A
S
G
Q
N
S
T
I
T
G
T
L
A
G
------
Q
I
V
M
E
G
----
F
L
R
L
S
I
P
N
W
L
R
R
L
I
T
R
S
L
A
V
I
P
V
I
I
C
L
I
I
F
K
G-
N
S
E
K
I
E
Q
--
L
L
V
F
S
Q
V
F
L
S
I
---
A
L
P
F
S
L
I
P
L
Q
L
A
T
S
N
K
K
L
M
G
P
F
I
N
K
T
W
V
N
I
I
S
W
T
L
I
V
I
L
S
G
L
N
V
-
Y
--------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
91.99
36%
-122
- C4 -
4WGW
-
?
A:
[5-399]
------------------------------------------------------------------------------------------
V
G
Y
M
D
P
G
N
W
I
T
S
M
Q
G
G
A
Q
Y
G
---
Y
T
L
L
F
V
I
L
I
S
S
----
L
A
A
-
M
L
-----
L
Q
S
M
T
V
R
L
-------
G
I
A
T
G
K
D
L
A
Q
M
T
R
H
F
L
S
K
P
V
A
I
I
-
F
-
W
I
I
A
E
L
A
I
I
A
T
D
I
A
E
V
I
G
-------
S
A
I
A
L
D
L
-----
I
--------
F
--
G
-
I
P
L
I
-------
V
G
A
L
I
T
V
F
D
V
F
L
L
L
F
I
M
R
--
F
G
F
R
K
I
---
E
------
A
I
V
G
T
L
I
F
T
V
L
A
----
I
F
V
F
E
V
F
I
S
S
P
Q
L
T
D
I
L
N
G
-
F
V
P
H
K
E
I
V
T
N
-
Q
G
I
L
Y
I
A
-
L
G
I
I
G
A
T
I
M
P
--
H
N
L
Y
L
H
S
S
I
V
Q
S
R
K
Y
D
R
H
D
N
E
E
K
A
Q
A
--
I
K
Y
A
T
I
D
S
N
L
Q
L
S
I
A
F
V
V
N
C
L
L
L
T
L
G
A
A
L
F
F
G
T
K
T
N
D
L
--------------------------------
G
G
F
Y
--------------------
D
L
Y
H
A
L
K
T
E
P
V
L
G
A
T
L
G
G
V
M
S
T
L
F
A
V
A
L
-
L
A
S
G
Q
N
S
T
I
T
G
T
L
A
G
------
Q
I
V
M
E
G
----
F
L
R
L
S
I
P
N
W
L
R
R
L
I
T
R
S
L
A
V
I
P
V
I
I
C
L
I
I
F
K
G-
N
S
E
K
I
E
Q
--
L
L
V
F
S
Q
V
F
L
S
I
---
A
L
P
F
S
L
I
P
L
Q
L
A
T
S
N
K
K
L
M
G
P
F
I
N
K
T
W
V
N
I
I
S
W
T
L
I
V
I
L
S
G
L
N
V
-
Y
--------------------------------------------------------------------------------------------------
15
Fugue
66.94
15%
-115
- C4 -
4R3Z
-
SYRC_HUMAN
B:
[17-675]
DV
L
V
S
E
C
S
A
R
L
L
Q
Q
E
E
E
I
K
S
L
T
A
E
I
D
R
L
K
N
C
G
C
L
G
A
S
P
N
L
E
Q
L
Q
E
E
N
L
K
L
K
Y
R
L
N
I
L
R
K
S
L
Q
A
E
R
N
--
K
P
T
K
N
M
I
N
I
I
S
R
L
Q
E
V
F
G
H
A
I
K
A
A
Y
P
D
L
E
N
P
P
L
L
V
T
P
S
Q
Q
A
K
FGD
Y
Q
C
N
S
A
M
G
I
S
Q
----
M
L
K
-
T
K
E
Q
K
V
N
P
R
E
I
A
E
N
I
T
K
H
LPDN
E
C
I
E
K
V
E
I
A
G
P
G
F
I
N
V
H
L
R
K
D
F
V
-
S
-
E
Q
L
T
S
L
L
V
N
G
V
Q
L
P
A
L
G
E
-------
N
K
K
V
I
V
D
F
S
SPN
I
--------
A
--
K
-
E
M
H
V
-------
G
H
L
R
S
T
I
I
G
E
S
I
S
R
L
F
E
F
A
G
Y
D
V
L
R
L
---
N
HVGDWG
T
Q
F
G
M
L
I
A
H
L
Q
D
----
K
F
P
-
D
Y
L
T
V
S
P
P
I
G
D
-
L
Q
V
F
Y
K
E
S
K
K
R
F
D
T
E
E
E
F
K
K
-
R
-
A
Y
Q
C
V
V
L
L
Q
G
--
K
N
P
D
I
T
K
A
W
K
L
I
C
D
V
S
R
Q
E
L
N
K
I
Y
D
A
--
L
D
V
S
L
I
E
R
G
E
S
F
Y
Q
D
R
M
-
N
D
I
V
K
E
F
E
D
R
G
F
V
Q
-
V
D
D
G
R
K
I
V
F
V
P
G
C
S
I
P
L
T
IVKSDGGYT
Y
D
T
S
D
L
A
A
I
K
Q
R
L
F
E
E
K
A
D
M
I
I
Y
V
V
D
NGQ
S
V
H
F
Q
T
I
F
---
A
A
A
Q
M
I
G
W
Y
-
D
P
K
V
T
R
V
F
H
A
G
F
G
V
V
L
G
E
D
K
K
K
F
K
T
R
S
G
ETVR
L
M
D
L
L
G
E
G
L
K
R
S
M
D
K
L
K
E
K
E
R
D
K
V
L
T
A
E
E
L
N
A
A
Q
T
S
V
-
A
Y
G
C
I
--
K
Y
A
D
L
S
H
NR
L
N
D
Y
I
F
S
F
D
K
M
L
DD
R
G
N
T
A
A
Y
L
L
Y
A
F
T
R
I
R
S
I
-
A
R
L
A
N
-----
I
D
E
E
M
L
Q
K
A
A
R
E
T
K
I
-
L
L
D
H
E
K
E
W
K
L
G
R
C
I
L
R
F
P
--
E
I
L
Q
K
I
L
D
D
L
F
L
H
T
L
-
C
D
Y
I
Y
E
L
A
T
A
F
T
E
F
Y
D
S
C
Y
C
V
E
K
D
R
Q
T
G
K
I
L
K
V
N
M
W
R
M
L
L
C
E
A
V
A
A
V
M
A
K
G
F
D
I
L
G
I
K
P
V
Q
RM
13
Fugue
65.68
22%
-121
- C4 -
4CI2
1
CRBN_CHICK
B:
[71-451]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
I
N
F
D
-
T
-
S
L
P
T
S
H
M
Y
L
G
S
D
M
E
E
F
H
G
R
T
L
H
D
D
D
S
C
Q
V
I
P
V
L
P
---
H
VM
V
M
L
I
PG
Q
--
T
-
L
P
L
Q
L
F
H
P
Q
E
V
S
M
V
R
N
L
I
Q
K
D
R
T
F
A
V
L
A
Y
--
S
N
V
R
E
R
---
E
------
A
H
F
G
T
T
A
E
I
Y
A
Y
R
E
E
Q
E
Y
G
I
E
T
V
K
V
K
A
I
G
R
Q
R
F
K
V
L
E
I
R
T
----
Q
S
-
D
G
I
Q
Q
-
A
K
V
Q
I
L
P
E
R
V
L
P
--
S
T
M
S
A
V
Q
L
Q
S
L
S
R
R
H
I
R
A
F
R
Q
W
W
Q
K
Y
--
Q
K
R
K
F
H
C
A
S
L
T
S
W
P
P
W
L
Y
S
L
Y
D
----
A
E
T
L
M
E
-
R
V
K
R
Q
L
H
E
W
D
E
N
L
K
D
E
--------------------
S
L
P
T
N
P
I
D
F
S
Y
R
V
A
-----------
A
------------
C
L
P
I
D
D
A
L
R
I
Q
L
L
K
I
------
G
S
A
I
Q
R
L
R
C
E
------
L
D
I
M
N
K
----
C
T
S
L
C
C
K
Q
C
Q
D
T
E
I
T
T
K
N
E
I
F
S
L
S
L
-
C
G
P
M
A
--
A
Y
V
N
P
H
G
Y-
I
H
E
T
L
T
V
Y
K
A
C
---
N
--------
L
N
L
S
G
R
P
S
T
E
H
S
W
F
P
G
Y
A
W
T
I
A
Q
C
R
----
I
C
G
N
H
M
G
W
K
F
T
A
T
K
K
D
M
S
P
Q
K
F
W
G
L
TR
S
A
L
L
P
R
-------------------------------------------------------------------------
14
Fugue
41.11
10%
-9
- C3 -
3VHX
-
KIF23_HUMAN
B:
[8-113]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
Q
N
A
P
P
I
R
L
R
H
R
R
S
R
-
S
A
G
D
R
-
W
-
V
D
H
K
P
A
S
N
M
Q
--
T
E
T
V
M
Q
P
H
V
P
H
A
I
T
V
S
V
A
N
E
K
A
L
A
K
C
--
E
K
Y
M
L
T
H
Q
E
L
A
S
D
G
E
I
E
T
K
L
I
K
G
D
I
Y
K
T
R
G
G
G
-
Q
S
V
Q
F
T
D
I
E
T
L
K
Q
E
S
P
--------------------
N
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
HHSearch
38.02
14%
-88
- C4 -
2XQ2
2
SGLT_VIBPH
A:
[58-195]
--------------------------------------------------------------------------------------
A
S
L
I
A
A
N
I
S
A
E
Q
F
I
G
M
S
G
S
G
Y
S
I
G
---
L
A
I
A
S
Y
E
W
M
S
A
I
T
L
I
I
V
G
-
K
Y
-----
F
L
P
I
F
I
E
K
----------
G
I
Y
T
I
P
E
F
V
E
K
R
F
N
K
K
L
K
T
I
-
L
A
V
F
W
I
S
L
Y
I
F
V
N
L
T
S
V
L
Y
L
-------
G
G
L
A
L
E
T
I
L
---------------
G
-
I
P
L
M
-------
Y
S
I
L
G
L
A
L
F
A
L
V
Y
S
I
Y
G
G
----
V
V
W
T
---
D
------
V
I
Q
V
F
F
L
V
L
G
G
F
----
M
T
T
Y
M
A
V
S
F
I
G
G
T
D
G
W
F
A
G
V
S
K
M
V
D
A
A
P
G
H
-
F
E
M
I
L
-
D
-
Q
S
N
P
Q
Y
M
N
L
P
--
G
I
A
V
L
I
G
G
L
W
V
A
N
L
Y
Y
W
G
F
N
Q
Y
I
I
Q
R
--
T
L
A
A
K
S
V
S
E
A
Q
K
G
I
V
F
A
A
F
L
A
L
I
V
P
F
L
V
V
L
P
G
-
I
A
A
Y
V
I
T
S
D
P
Q
L
M
A
S
L
--------------------
G
N
L
P
S
A
A
N
A
D
K
A
Y
P
-----------
W
L
T
---
Q
F
L
P
V
G
V
K
G
V
V
F
A
A
L
A
A
A
I
V
S
S
-
L
A
S
M
L
N
S
T
A
T
I
F
T
M
D
------
I
Y
K
E
Y
I
----
S
P
D
S
G
D
H
K
L
V
N
V
G
R
T
A
A
V
V
A
L
I
I
A
A
-
L
I
A
P
M
--
L
G
G
I
G
Q
C
--
F
Q
Y
I
Q
E
Y
T
G
L
V
---
S
P
G
I
L
A
V
F
L
L
G
L
F
W
K
K
T
T
S
K
G
A
I
I
G
V
V
A
S
I
P
F
A
L
F
L
K
F
M
P
L
S
M
P
-
F
M
D
Q
M
L
Y
T
L
L
F
T
M
V
V
I
A
F
--
T
S
L
S
T
S
I
N
D
D
D
P
K
G
I
S
V
T
S
S
M
F
V
T
D
R
S
F
N
I
A
A
Y
G
I
M
I
V
L
A
V
L
Y
T
L
F
W
V
N
A
D
A
E
I
T
L
I
I
---------------------
4
HHSearch
37.14
11%
-100
- C4 -
2JLN
-
?
A:
[62-179]
--------------------------------------------------------------------------------------------------------------------
I
V
A
I
A
A
G
C
----
T
I
A
-
V
I
-----
L
L
F
F
T
Q
S
A
-------
A
I
R
W
G
I
N
F
T
V
A
A
R
M
P
F
G
I
R
G
S
L
I
-
P
-
I
T
L
K
A
L
L
S
L
F
W
F
G
F
Q
T
W
L
-------
G
A
L
A
L
D
E
I
T
---
R
--------
L
L
T
G
F
T
N
L
P
-------
L
W
I
V
I
F
G
A
I
Q
V
V
T
T
---
F
--
Y
G
I
T
F
I
---
R
------
W
M
N
V
F
A
S
P
V
L
L
A
----
M
G
V
Y
M
V
Y
L
M
L
D
G
A
D
V
S
L
G
E
V
M
S
M
G
G
E
N
P
G
M
-
P
F
S
T
A
-
I
-
M
I
F
V
G
G
W
I
A
V
--
V
V
S
I
H
D
I
V
K
E
C
K
V
D
P
N
A
S
R
E
G
Q
T
K
A
D
--
A
R
Y
A
T
A
Q
W
L
G
M
V
P
A
S
I
I
F
G
F
I
G
A
A
S
M
V
L
V
G
E
W
-
N
P
V
I
A
I
T
E
V
V
G
G
V
S
I
P
--------------------
M
A
I
L
F
Q
V
F
V
L
L
A
T
W
-----------
S
T
N
---
P
A
A
N
L
L
S
P
A
Y
T
L
C
S
T
F
P
R
V
F
T
F
-
K
T
G
V
I
V
S
A
V
V
G
L
L
M
M
------
P
W
Q
F
A
G
----
V
L
N
T
F
L
N
L
L
A
S
A
L
G
P
L
A
G
I
M
I
S
D
Y
F
-
L
V
R
R
R
--
R
I
S
L
H
D
L
--
Y
R
T
K
G
I
Y
T
Y
W
R
---
G
V
N
W
V
A
L
A
V
Y
A
V
A
L
A
V
S
F
L
T
P
D
L
M
F
V
T
G
L
I
A
A
L
L
L
H
I
P
A
M
R
W
V
A
-
K
T
F
P
L
F
S
E
A
E
S
R
N
E
D
Y
L
R
--
P
I
G
P
---------------------------------------------------------------------------
16
Fugue
36.08
26%
530
- C4 -
1ETF
-
REV_HV1W2
B:
[1-23]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
T
R
Q
A
R
R
N
R
R
R
R
W
R
E
R
--
Q
R
A
A
A
A
R
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
HHSearch
36.01
14%
-90
- C4 -
3DH4
1
?
A:
[61-166]
------------------------------------------------------------------------------------
V
G
A
S
L
I
A
A
N
I
S
A
E
Q
F
I
G
M
S
G
S
G
Y
S
I
G
---
L
A
I
A
S
Y
E
W
M
S
A
----
I
T
L
I
I
V
-----
G
K
Y
F
L
P
I
F
-------
I
E
K
G
I
Y
T
I
P
E
F
V
E
K
R
F
N
K
K
L
K
T
I
L
A
-
V
F
W
I
S
L
Y
I
F
V
N
L
T
S
V
L
Y
L
-------
G
G
L
A
L
E
T
I
L
---------------
G
-
I
P
L
M
-------
Y
S
I
L
G
L
A
L
F
A
L
V
Y
S
I
----------
V
V
W
T
D
------
V
I
Q
V
F
F
L
V
L
G
G
F
----
M
T
T
Y
M
A
V
S
F
I
G
G
T
D
G
W
F
A
G
V
S
K
M
V
D
A
A
P
G
H
-
F
E
M
I
L
-
D
-
Q
S
N
P
Q
Y
M
N
L
P
--
G
I
A
V
L
I
G
G
L
W
V
A
N
L
Y
Y
W
G
F
N
Q
Y
I
I
Q
R
--
T
L
A
A
K
S
V
S
E
A
Q
K
G
I
V
F
A
A
F
L
K
L
I
V
P
F
L
V
V
L
P
G
-
I
A
A
Y
V
I
T
S
D
P
Q
L
M
A
S
L
--------------------
G
D
I
A
A
T
N
L
P
S
A
A
N
A
-----------
D
K
A
---
Y
P
W
L
T
Q
F
L
P
V
G
V
K
G
V
V
F
A
A
L
A
A
-
A
I
V
S
S
L
A
S
M
L
N
S
T
A
T
------
I
F
T
M
D
I
----
Y
K
E
Y
I
S
P
D
S
G
D
H
K
L
V
N
V
G
R
T
A
A
V
V
A
-
L
I
I
A
C
--
L
I
A
P
M
L
G
--
G
I
G
Q
A
F
Q
Y
I
Q
E
---
Y
T
G
L
V
S
P
G
I
L
A
V
F
L
L
G
L
F
W
K
K
T
T
S
K
G
A
I
I
G
V
V
A
S
I
P
F
A
L
F
L
K
F
M
-
P
L
S
M
P
F
M
D
Q
M
L
Y
T
L
L
F
T
M
--
V
V
I
A
F
T
S
L
S
T
S
I
N
D
D
D
P
K
G
I
S
V
T
S
S
M
F
V
T
D
R
S
F
N
I
A
A
Y
G
I
M
I
V
L
A
V
L
Y
T
L
F
W
V
L
Y
K
-----------------------
19
Fugue
34.84
16%
507
* C4 *
4Q5U
-
C:
[1-24]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
R
K
E
V
I
R
N
K
I
R
A
I
G
K
M
--
A
R
V
F
S
V
L
R
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
Fugue
34.61
27%
258
- C4 -
3H8D
1
DAB2_RAT
E:
[11-48]
--------------------------------------------
S
G
T
S
S
--
A
F
S
S
Y
F
N
N
K
V
G
I
P
Q
E
HV
D
H
D
D
F
D
A
N
Q
L
L
N
K
I
N
-
E
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
HHSearch
32.46
30%
1540
- C2 -
2KSS
-
CARS_MYXXA
A:
[73-82]
-----
D
P
A
T
Q
Y
--
P
D
D
P
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
HHSearch
30.23
19%
442
- C4 -
2LJW
-
?
A:
[2-17]
-------------------------------------------------------------------------------------------------------------------------------------------------------------
T
G
Q
E
L
R
Q
L
L
L
D
K
W
G
Y
S
Y
D
V
Q
-
F
-
R
R
T
Q
G
K
I
F
L
Q
V
M
W
K
Y
L
E
Q
-------
A
S
F
P
M
N
E
T
E
---
Y
--------
Q
--
E
-
H
L
D
S
-------
V
A
N
Y
L
H
A
L
G
G
A
V
Q
V
K
T
F
I
--
T
Q
T
K
E
R
---
P
------
R
L
G
K
A
V
S
I
P
L
D
L
----
G
E
R
A
S
E
W
I
I
L
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
Fugue
30.07
21%
340
- C4 -
2WWB
1
RL39_YEAST
O:
[1-37]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
A
AQ
K
S
F
R
I
K
Q
K
M
A
K
A
K
K
Q
N
R
P
L
P
Q
W
I
R
L
R
TN
N
T
I
R
Y
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
HHSearch
28.97
23%
452
- C4 -
3R12
2
DEOC_THEMA
A:
[238-259]
----------------------------------------------------------------------------------------------------------------------------------------------
G
A
D
R
I
-------
G
T
S
S
G
V
K
I
V
Q
G
G
E
E
R
Y
G
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
HHSearch
28.82
20%
55
- C4 -
3GIA
3
Y609_METJA
A:
[262-302]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
A
A
K
P
F
L
G
N
L
G
F
L
L
I
S
I
G
A
-
L
F
S
I
S
S
A
M
N
A
T
I
Y
G
G
------
A
N
V
A
Y
S
----
L
A
K
D
G
E
L
P
E
F
F
E
R
K
V
W
F
K
S
T
E
G
L
Y
I
-
T
S
A
L
G
--
V
L
F
A
L
L
F
--
N
M
E
G
V
A
S
I
T
S
A
---
V
F
M
V
I
Y
L
F
V
I
L
S
H
Y
I
L
I
D
E
V
G
G
R
K
E
I
V
I
F
S
F
I
V
V
L
G
V
F
L
L
L
L
Y
Y
-
Q
W
I
T
N
R
F
V
F
Y
G
I
I
A
T
F
I
G
--
V
L
I
F
E
I
I
Y
R
K
V
T
K
R
T
F
S
N
N
M
Y
V
K
S
-------------------------------------------------------
6
HHSearch
26.52
14%
83
- C4 -
3L1L
1
ADIC_ECO57
A:
[265-306]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
A
R
M
A
L
G
D
T
A
G
A
I
V
S
F
C
A
-
A
A
G
C
L
G
S
L
G
G
W
T
L
L
A
------
G
Q
T
A
K
A
----
A
A
D
D
G
L
F
P
P
I
F
A
R
V
N
K
A
G
T
P
V
A
G
L
I
-
I
V
G
I
L
--
M
T
I
F
Q
L
S
--
S
I
S
P
N
A
T
K
E
F
G
---
L
V
S
S
V
S
V
I
F
T
L
V
P
Y
L
Y
T
C
A
A
L
L
L
L
G
H
G
H
F
G
K
A
R
P
A
Y
L
A
V
T
T
I
A
F
-
L
Y
C
I
W
A
V
V
G
S
G
A
K
E
V
M
W
S
--
F
V
T
L
M
V
I
T
A
M
Y
A
L
N
Y
N
R
L
H
K
N
P
Y
P
L
D
A
----------------------------------------------------
8
HHSearch
2.00
11%
2932
- C1 -
2GPV
-
NCOR2_HUMAN
G:
[10-15]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
K
A
L
M
G
----------------------------------------------------------------------------------------------------------------------------