@TOME V2.2
(Nov 2016)
Ref.
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : S13A4_HUMAN: (2015-12-09 )
MGLLQGLLRVRKLLLVVCVPLLLLPLPVLHPSSEASCAYVLIVTAVYWVSEAVPLGAAALVPAFLYPFFGVLRSNEVAAEYFKNTTLLLVGVICVAAAVEKWNLHKRIALRMVLMAGAKPGMLLLCFMCCTTLLSMWLSNTSTTAMVMPIVEAVLQELVSAEDEQLVAGNSNTEEAEPISLDVKNSQPSLELIFVNEESNADLTTLMHNENLNGVPSITNPIKTANQHQGKKQHPSQEKPQVLTPSPRKQKLNRKYRSHHDQMICKCLSLSISYSATIGGLTTIIGTSTSLIFLEHFNNQYPAAEVVNFGTWFLFSFPISLIMLVVSWFWMHWLFLGCNFKETCSLSKKKKTKREQLSEKRIQEEYEKLGDISYPEMVTGFFFILMTVLWFTREPGFVPGWDSFFEKKGYRTDATVSVFLGFLLFLIPAKKPCFGKKNDGENQEHSLGTEPIITWKDFQKTMPWEIVILVGGGYALASGSKSSGLSTWIGNQMLSLSSLPPWAVTLLACILVSIVTEFVSNPATITIFLPILCSLSETLHINPLYTLIPVTMCISFAVMLPVGNPPNAIVFSYGHCQIKDMVKAGLGVNVIGLVIVMVAINTWGVSLFHLDTYPAWARVSNITDQA
Atome Classification :
(20 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150......-.160....------...170.......----180.......190.......200.......210.......220.......230.......240.......250........260.......270.......280.......290.......300....-...310.......320.......330.......340.......350.......360.......370.......380.......390...--....400.......410.......420.......430.......440.......450.......460.......470.......480.......490...-....500.......510.......520.......530.......540.......550.......560.......570.......580.......590.........600.......610.......620....
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
M
G
L
L
Q
G
L
L
R
V
R
K
L
L
L
V
V
C
V
P
L
L
LLPLPVLHPSSEA
S
C
A
Y
V
L
I
V
T
A
V
Y
W
V
S
EAVPL
G
A
A
A
L
V
P
A
F
L
Y
P
F
F
G
V
LRS
N
E
V
A
A
E
Y
FKN
T
T
L
L
L
V
G
V
I
C
V
A
A
A
V
E
K
W
N
L
H
K
R
I
A
L
R
M
V
L
MAGAK
P
G
M
L
L
L
C
F
M
C
C
T
T
L
L
S
M
W
LSNTST
T
A
M
V
M
P
I
V
E
A
V
L
Q
E
L
-VSAED
E
Q
L
------VAGNSNTEEAE
P
I
----
S
L
D
VKNSQP
S
L
E
L
I
F
VNEESNA
D
L
T
T
L
MHNENLNGVPSITNPIKT
A
N
QHQGKKQHPSQEKPQVLTP
S
P
R
K
Q
K
-
L
N
R
K
Y
R
S
H
H
D
Q
M
I
C
K
C
L
S
L
S
I
S
Y
S
ATIGG
L
T
T
I
IGTS
T
S
L
I
F
L
EHFNNQY
P
A
A
E
V
-VNF
G
T
W
F
L
F
S
F
P
I
S
L
I
M
L
V
V
S
W
F
W
M
H
W
L
F
LGC
N
F
K
E
T
CS
L
S
K
K
K
K
T
K
R
E
Q
L
S
E
K
R
I
Q
E
E
Y
E
KLGDIS
Y
P
E
M
V
T
G
F
F
F
I
L
M
T
V
L
W
FTREP--GFVP
G
W
D
S
F
F
E
KKGYRT
D
A
T
V
S
V
F
L
G
F
L
L
F
L
IPAKKPCFGKKNDGENQEHSLGTE
P
I
I
T
W
K
D
F
QKTM
P
W
E
I
V
I
L
VGG
G
Y
A
LASGSKSSG
L
S
T
W
IGN
Q
M
L
S-LSSL
P
P
W
A
V
T
L
L
A
C
I
L
V
S
I
V
T
E
F
VSNP
A
T
I
T
I
F
L
P
I
L
CSLSE
T
L
HINP
L
Y
T
L
I
P
V
T
M
C
I
S
F
A
V
M
LPVGNPP
N
A
I
V
F
SYGH
C
Q
I
K
D
M
V
K
AGL
G
V
N
V
--
I
G
L
V
I
V
M
V
A
I
NTW
G
V
S
L
F
H
LDTYP
A
W
A
R
VSNITDQA
1
PsiBlast_PDB
83.43
26%
-119
- C4 -
4F35
-
?
D:
[170-440]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
G
V
A
Y
S
A
S
I
G
G
I
A
T
L
V
G
S
P
P
---------
N
A
I
A
A
A
E
V
G
L
S
F
T
D
W
M
K
F
G
L
P
T
A
M
M
M
L
P
M
A
I
A
I
L
Y
F
L
L
----------------------------
V
N
W
D
K
------
G
K
V
V
T
L
G
I
F
G
L
T
V
F
L
W
I
F
S
S
P
I
N
A
A
L
G
G
F
K
S
F
--------
D
T
L
V
A
--
L
G
A
I
L
M
L
S
F
A
R
---------------------
V
V
H
W
K
E
I
Q
K
T
A
D
W
G
V
L
L
L
F
G
G
G
L
C
L
S
N
V
L
K
Q
T
G
T
S
V
F
L
A
N
A
L
S
D
M
V
S
H
M
G
I
F
V
V
I
L
V
V
A
T
F
V
V
F
L
T
E
F
A
S
N
T
A
S
A
A
L
L
I
P
V
F
A
T
V
A
E
A
F
G
M
S
P
V
L
L
S
V
L
I
A
V
A
A
S
C
A
F
M
L
P
V
A
T
P
P
N
A
I
V
F
A
S
G
H
I
K
Q
S
E
M
M
R
V
G
L
Y
L
N
I
A
C
I
G
L
L
T
A
I
A
M
L
F
W
Q
-----------------------
4
PsiBlast_PDB
64.31
26%
-74
- C4 -
2OHV
1
MURI_STRP1
A:
[87-234]
--------------------------------------------------------------
A
L
D
I
P
V
L
G
V
V
L
P
G
A
S
A
A
--
I
K
S
T
T
K
G
Q
V
G
V
I
G
T
P
M
T
V
A
S
D
I
Y
R
K
K
I
Q
L
-------
L
A
P
S
I
Q
V
R
S
-
L
A
C
P
K
F
V
P
I
V
E
S
N
E
M
C
S
S
I
A
K
K
I
V
Y
D
S
L
A
P
L
-
V
G
K
I
D
-
T
L
------
V
L
G
C
T
H
Y
P
L
L
R
P
I
----
I
Q
N
V
M
G
--
P
S
V
K
L
I
D
S
G
A
E
C
V
R
D
I
S
V
L
L
N
Y
F
D
I
N
G
-----------
N
Y
H
Q
-
A
V
E
H
R
F
F
T
T
A
N
P
E
I
F
Q
E
I
A
S
I
-
W
L
K
Q
K
I
N
V
E
H
V
T
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
62.00
26%
-68
- C4 -
2OHG
-
MURI_STRP1
A:
[87-234]
--------------------------------------------------------------
A
L
D
I
P
V
L
G
V
V
L
P
G
A
S
A
A
--
I
K
S
T
T
K
G
Q
V
G
V
I
G
T
P
M
T
V
A
S
D
I
Y
R
K
K
I
Q
L
-------
L
A
P
S
I
Q
V
R
S
-
L
A
C
P
K
F
V
P
I
V
E
S
N
E
M
C
S
S
I
A
K
K
I
V
Y
D
S
L
A
P
L
-
V
G
K
I
D
-
T
L
------
V
L
G
C
T
H
Y
P
L
L
R
P
I
----
I
Q
N
V
M
G
--
P
S
V
K
L
I
D
S
G
A
E
C
V
R
D
I
S
V
L
L
N
Y
F
D
I
N
G
-----------
N
Y
H
Q
-
A
V
E
H
R
F
F
T
T
A
N
P
E
I
F
Q
E
I
A
S
I
-
W
L
K
Q
K
I
N
V
E
H
V
T
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
61.04
26%
-73
- C4 -
2OHO
-
MURI_STRP1
A:
[96-243]
--------------------------------------------------------------
A
L
D
I
P
V
L
G
V
V
L
P
G
A
S
A
A
--
I
K
S
T
T
K
G
Q
V
G
V
I
G
T
P
M
T
V
A
S
D
I
Y
R
K
K
I
Q
L
-------
L
A
P
S
I
Q
V
R
S
-
L
A
C
P
K
F
V
P
I
V
E
S
-----
S
I
A
K
K
I
V
Y
D
S
L
A
P
L
-
V
G
K
I
D
-
T
L
------
V
L
G
C
T
H
Y
P
L
L
R
P
I
----
I
Q
N
V
M
G
--
P
S
V
K
L
I
D
S
G
A
E
C
V
R
D
I
S
V
L
L
N
Y
F
D
I
N
G
-----------
N
Y
H
Q
K
A
V
E
H
R
F
F
T
T
A
N
P
E
I
F
Q
E
I
A
S
I
-
W
L
K
Q
K
I
N
V
E
H
V
T
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
Fugue
45.31
27%
138
- C4 -
2Q97
1
?
T:
[1-109]
---------------------------------------------------------------------------------------------------------------------------------------------------------
M
Q
Q
E
L
G
L
L
R
P
E
E
R
L
------
I
A
G
Q
A
K
A
A
A
L
Q
T
V
HQLG
A
V
A
L
T
P
E
Q
A
K
A
A
L
L
D
E
I
L
R
A
T
Q
N
L
D
-
L
R
K
Y
E
N
L
N
-----
T
E
Q
Q
K
A
Y
E
Q
V
Q
R
D
L
S
Q
L
S
P
E
T
K
A
L
L
I
E
N
Q
R
K
E
K
T
L
L
E
K
A
R
K
L
F
Q
R
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
40.44
27%
114
- C2 -
3RBB
1
NEF_HV1A2
A:
[72-121]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
W
I
Y
H
T
Q
--
G
Y
F
P
D
W
Q
N
Y
T
P
G
P
G
I
R
Y
P
L
T
----
F
G
W
C
F
K
L
V
P
V
E
P
E
K
V
E
E
A
N
E
G
E
N
N
S
L
L
H
P
M
S
L
H
G
M
E
D
A
E
K
E
V
L
V
W
R
F
D
S
K
L
A
F
H
H
M
A
R
E
L
H
P
E
Y
Y
K
------------------------------------------------------------------------------------------------------------------------------------------------
17
Fugue
40.03
26%
484
- C4 -
4MQV
-
SMAL1_HUMAN
B:
[1-26]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
T
E
E
Q
R
K
K
I
E
E
N
R
Q
K
A
L
A
R
R
A
E
K
L
L
A
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
Fugue
39.22
15%
525
- C4 -
1I5K
-
D:
[402-427]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
K
L
T
A
D
A
E
L
Q
R
L
K
N
E
R
H
E
E
A
E
L
E
R
L
K
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
Fugue
35.48
5%
80
- C4 -
1XQ8
-
SYUA_HUMAN
A:
[1-140]
---------------------------------------------------------------------------------------------------------------------------------
M
D
V
F
M
K
G
L
S
K
A
K
E
G
V
V
A
A
A
E
K
T
K
Q
G
V
A
E
A
-
A
G
K
T
K
E
G
V
LYVGSK
T
K
E
G
V
V
H
G
V
A
T
V
A
----
E
K
T
K
E
Q
V
T
N
V
G
G
A
V
V
T
G
V
T
A
V
A
Q
K
T
V
E
G
A
G
S
I
A
A
A
T
G
F
V
K
K
D
Q
L
G
K
N
E
E
G
A
P
Q
E
G
I
L
E
D
M
P
V
D
P
D
N
E
A
Y
E
M
P
-
S
E
E
G
Y
Q
D
Y
E
P
E
A
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
Fugue
34.69
20%
413
- C4 -
3SJD
-
GET2_YEAST
D:
[15-44]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
E
A
E
K
R
R
L
L
R
E
R
R
Q
K
K
F
S
N
G
G
A
S
S
R
L
N
K
I
T
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
32.79
34%
47
- C4 -
5A63
-
?
D:
[28-69]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
L
W
L
V
N
I
F
W
F
F
R
E
A
--
F
L
V
P
A
Y
T
E
Q
S
Q
I
K
G
Y
V
W
R
S
A
V
----
G
F
L
F
W
V
I
V
L
T
S
W
I
T
I
F
Q
I
Y
R
P
R
W
G
A
L
G
D
Y
L
S
F
T
I
P
L
G
T
P
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
HHSearch
32.20
28%
389
- C4 -
1A0R
-
PHOS_BOVIN
P:
[13-35]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
E
G
Q
A
S
H
T
G
P
K
G
V
I
N
D
W
R
K
F
K
L
E
S
E
F
S
R
K
M
S
V
Q
E
Y
E
L
I
H
K
-
D
K
E
D
E
N
C
L
R
K
Y
R
R
Q
C
M
Q
D
M
H
Q
K
L
S
F
G
P
R
Y
G
F
V
Y
E
L
E
S
G
E
Q
F
L
E
T
I
E
K
E
Q
K
I
T
T
I
V
-
V
H
I
Y
E
D
G
I
K
G
C
D
A
L
N
S
S
L
I
C
L
A
A
E
Y
P
M
V
K
F
C
K
I
K
A
S
N
T
G
A
G
D
R
F
S
S
D
V
L
P
T
L
L
V
Y
K
G
G
E
L
L
S
N
F
I
S
V
T
E
Q
L
A
E
E
F
F
T
G
D
V
E
S
F
L
N
E
Y
G
L
--
L
P
E
K
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
Fugue
30.86
9%
121
- C4 -
1SA0
-
STMN4_RAT
E:
[1-138]
-----------------------------------------------------------------------------------------------------------------------------------
A
D
M
E
V
I
E
L
N
K
C
T
S
G
Q
S
F
E
V
I
L
K
P
P
S
F
D
-
P
S
L
E
E
I
Q
---------
K
K
L
E
A
A
E
E
R
R
K
----
Y
Q
E
A
E
L
L
K
H
L
A
E
K
R
E
H
E
R
E
V
I
Q
K
A
I
E
E
N
N
N
F
I
K
M
A
K
E
K
L
A
Q
K
M
E
S
N
K
E
N
R
E
A
H
L
A
A
M
L
E
R
L
Q
E
K
D
K
H
A
E
E
V
R
-
K
N
K
E
L
K
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
Fugue
29.78
33%
590
- C4 -
2DOH
-
C:
[4-28]
---------------------------------------------------------------------------------------------------------------------------------------------------------------
L
T
A
D
A
E
L
Q
------
R
L
K
N
E
R
H
E
E
A
E
L
E
----
R
L
S
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
Fugue
28.15
34%
523
* C4 *
1I5K
-
PAM_STRPY
C:
[302-327]
------------------------------------------------------------------------------------------------------------------------------------------------------------
E
K
-
L
T
A
D
A
E
L
Q
------
R
L
K
N
E
R
H
E
E
A
E
L
E
----
R
L
K
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
25
Fugue
28.13
12%
331
- C4 -
3ZS9
-
GET2_YEAST
C:
[4-34]
-----------------------------------------------------------------------------------------------------------------------------------------------------
L
T
E
A
E
K
R
R
L
-
L
R
E
R
R
Q
K
K
------
F
S
N
G
G
A
S
S
R
L
N
K
I
----
T
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
HHSearch
23.49
27%
682
- C4 -
2K1A
-
ITA2B_HUMAN
A:
[981-995]
--------------------------------------------------------------------------------------------
T
I
L
V
L
A
M
W
K
V
G
F
F
K
R
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
HHSearch
22.15
17%
202
- C4 -
2WWB
-
SC61G_CANFA
B:
[25-66]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
C
T
K
P
D
R
K
E
F
Q
K
I
A
M
A
T
A
I
G
F
A
I
M
G
F
I
G
F
F
V
K
L
I
H
I
P
I
N
N
I
I
V
G
G
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
HHSearch
17.59
10%
737
- C3 -
2FVN
-
AFAD_ECOLX
A:
[57-77]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
D
G
R
H
E
L
R
V
R
T
G
G
D
G
W
S
P
V
K
G
E
G
G
K
G
V
S
R
P
G
Q
E
E
Q
V
F
F
D
V
M
A
D
G
N
Q
D
I
A
P
G
E
Y
R
F
S
V
G
G
A
C
V
V
P
Q
E
D
N
-
K
Q
G
F
T
P
S
G
T
T
G
T
T
K
L
T
V
T
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
HHSearch
17.12
19%
544
- C4 -
3S8F
4
COXA_THET8
C:
[17-32]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
T
I
L
V
F
W
L
G
V
Y
A
V
F
F
A
R
G
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------