@TOME V2.2
(Nov 2016)
Ref.
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : S13A5_HUMAN: (2015-12-09 )
MASALSYVSKFKSFVILFVTPLLLLPLVILMPAKFVRCAYVIILMAIYWCTEVIPLAVTSLMPVLLFPLFQILDSRQVCVQYMKDTNMLFLGGLIVAVAVERWNLHKRIALRTLLWVGAKPARLMLGFMGVTALLSMWISNTATTAMMVPIVEAILQQMEATSAATEAGLELVDKGKAKELPGSQVIFEGPTLGQQEDQERKRLCKAMTLCICYAASIGGTATLTGTGPNVVLLGQMNELFPDSKDLVNFASWFAFAFPNMLVMLLFAWLWLQFVYMRFNFKKSWGCGLESKKNEKAALKVLQEEYRKLGPLSFAEINVLICFFLLVILWFSRDPGFMPGWLTVAWVEGETKYVSDATVAIFVATLLFIVPSQKPKFNFRSQTEEERKTPFYPPPLLDWKVTQEKVPWGIVLLLGGGFALAKGSEASGLSVWMGKQMEPLHAVPPAAITLILSLLVAVFTECTSNVATTTLFLPIFASMSRSIGLNPLYIMLPCTLSASFAFMLPVATPPNAIVFTYGHLKVADMVKTGVIMNIIGVFCVFLAVNTWGRAIFDLDHFPDWANVTHIET
Atome Classification :
(19 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.....-------..130.......140.......150.......160.......170.......180---.......190.......200.......210.......220.......230......-----.240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430.....-..440.......450.......460.......470.......480.......490.......500.......510.......520.......530.......540.......550.......560......
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
M
A
S
A
L
S
Y
V
S
K
F
K
S
F
V
I
L
F
V
T
P
L
L
L
L
P
L
V
I
LM
P
A
K
F
V
R
C
A
Y
V
I
I
L
M
A
I
Y
W
C
T
E
V
I
P
L
A
V
T
S
L
M
P
V
L
L
F
P
L
F
Q
I
L
D
S
R
Q
V
C
V
Q
Y
M
KDT
N
M
L
F
L
G
G
L
I
V
A
V
A
V
E
RW
N
L
H
K
R
I
A
L
R
T
L
L
WVGA
K
P
A
R
L
M
L
G
-------
F
M
G
V
T
A
L
L
S
M
W
I
SNTA
T
T
A
M
M
V
P
I
V
E
A
I
L
Q
Q
M
E
ATS
A
A
T
E
A
G
L
E
L
VDKGKAKELP---GS
Q
V
I
FEGPTLG
Q
Q
E
D
Q
E
R
K
R
L
C
K
A
M
T
L
C
I
C
Y
AASIGG
T
A
T
L
TGTGP
N
V
V
L
LG
Q
M
N
-----
E
LFPD
S
K
D
L
V
N
F
A
S
W
F
A
F
A
F
P
N
M
L
V
M
L
L
F
A
W
L
W
L
Q
F
V
Y
M
R
FNFKKSWGCGLESKK
N
E
K
A
A
L
K
V
L
Q
E
E
Y
R
KLGPL
S
F
A
E
I
N
V
L
I
C
F
F
L
L
V
I
L
W
FSRDPGFMPG
W
L
T
V
A
W
VEGE
T
K
YVS
D
A
T
V
A
I
F
V
A
T
L
L
F
IVPSQKPKFNFRSQT
E
E
ERKTPFYPPPLLDWKVTQEKV
P
W
G
I
V
L
L
LGG
G
F
A
LAKGSEASG
L
S
V
W
MGKQM-EPLHAV
P
P
A
A
I
T
L
I
L
S
L
L
V
A
V
F
T
E
CTSNVA
T
T
T
L
F
L
P
I
F
A
S
M
S
R
SIGLN
P
L
Y
I
M
L
PCTLSA
S
F
A
F
M
L
PVATPP
N
A
I
V
F
T
YGHL
K
V
A
D
M
V
K
T
G
V
I
M
N
I
I
G
V
F
C
V
F
L
A
V
N
T
WG
R
A
I
FDLDHFPDWANVTHIET
1
PsiBlast_PDB
85.31
35%
-74
- C3 -
4F35
-
?
D:
[295-434]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
V
H
W
K
E
I
Q
K
T
A
D
W
G
V
L
L
L
F
G
G
G
L
C
L
S
N
V
L
K
Q
T
G
T
S
V
F
L
A
N
A
L
S
D
M
V
S
H
M
G
I
F
V
V
I
L
V
V
A
T
F
V
V
F
L
T
E
F
A
S
N
T
A
S
A
A
L
L
I
P
V
F
A
T
V
A
E
A
F
G
M
S
P
V
L
L
S
V
L
I
A
V
A
A
S
C
A
F
M
L
P
V
A
T
P
P
N
A
I
V
F
A
S
G
H
I
K
Q
S
E
M
M
R
V
G
L
Y
L
N
I
A
C
I
G
L
L
T
A
I
A
M
L
F
W
Q
-------------------
23
Fugue
51.44
14%
11
- C2 -
1HQM
-
RPOZ_THEAQ
E:
[1-98]
---------------------------------------------------------------------------------------------------------------------------------------------------------
M
A
E
P
G
I
D
K
L
F
G
M
V
D
-----
S
K
Y
R
L
T
V
V
V
A
K
R
A
Q
Q
L
L
RHR
F
K
N
T
V
L
E
P
E
E
R
P
K
M
R
T
L
E
G
L
Y
D
D
P
N
A
V
T
W
A
M
K
E
L
L
T
G
R
L
F
F
G
E
N
L
V
P
E
D
R
L
Q
K
E
M
E
-----
R
L
Y
P
T
E
E
E
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
Fugue
46.85
18%
117
- C3 -
2JVG
-
SBI_STAAM
A:
[195-266]
--------------------------------------------------------------------------------------------------------------------------------------------------------
G
A
M
V
S
I
E
K
A
I
V
R
H
D
E
R
V
K
S
A
N
D
A
I
S
K
L
N
E
K
D
S
I
E
N
R
R
---
L
A
Q
R
E
V
N
K
A
P
M
D
V
K
E
H
L
Q
K
Q
L
--
D
A
L
V
A
Q
K
D
A
E
K
K
V
A
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
45.96
25%
-10
- C3 -
2Z1N
-
?
A:
[99-165]
--------------------------------------------------------------------------------------------
G
R
F
M
E
L
G
V
E
D
W
D
E
S
Y
R
L
L
A
R
S
A
V
W
V
G
R
R
A
A
E
Q
M
V
E
K
G
W
G
R
M
V
Y
I
G
S
V
T
L
L
R
P
W
Q
D
L
A
L
S
N
I
M
R
L
P
V
I
G
V
V
R
T
L
A
L
E
L
A
P
H
G
V
T
V
N
A
V
L
P
S
L
I
L
T
D
R
V
---
R
R
I
P
M
G
R
V
G
K
P
E
E
L
A
S
V
V
A
F
L
A
S
E
K
A
S
F
I
T
G
A
V
I
P
V
D
G
G
A
H
I
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
38.34
41%
340
- C1 -
3UJJ
5
?
L:
[87-125]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
C
Y
S
T
N
S
G
G
T
F
F
V
F
G
T
G
T
K
V
T
V
L
G
Q
P
K
ANPTV
T
L
F
P
P
S
S
E
E
L
Q
A
N
K
A
T
L
V
C
L
I
S
D
F
Y
P
G
A
V
T
V
A
W
K
A
D
S
S
P
V
K
A
G
V
E
T
T
T
P
S
K
Q
S
N
N
K
Y
A
A
S
S
Y
L
S
L
T
P
E
Q
W
K
S
H
R
S
Y
S
C
Q
V
T
H
E
G
S
T
V
E
K
T
V
A
P
T
E
C
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
Fugue
37.57
13%
206
- C3 -
1L2P
-
ATPF_ECOLI
A:
[62-122]
----------------------------------------------------------------------------------------------------------------------------------------------------------
T
D
Q
L
K
K
A
K
A
E
A
Q
V
I
I
E
Q
A
N
K
R
R
S
Q
I
L
D
E
A
K
A
E
A
E
Q
---
E
R
T
K
I
V
A
Q
A
Q
A
E
I
E
A
E
R
K
R
A
R
E
E
L
R
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
Fugue
37.43
21%
404
* C3 *
5CWW
-
?
C:
[1-32]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
R
A
R
E
A
K
R
K
A
T
L
R
M
L
R
E
S
L
A
R
V
G
P
N
V
V
R
L
R
D
D
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
Fugue
35.90
26%
535
- C3 -
2XZE
-
CHMP3_HUMAN
Q:
[18-40]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
E
D
E
E
E
E
E
E
A
L
E
A
M
Q
S
R
L
A
T
L
R
S
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
35.03
36%
296
* C4 *
3W8R
1
URK_THET8
A:
[76-108]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
L
L
R
G
L
P
V
E
M
P
V
Y
D
F
R
A
H
T
R
S
P
R
R
T
P
V
R
P
A
P
V
V
I
L
E
G
I
L
V
L
Y
P
K
E
L
R
D
L
M
D
L
K
V
F
V
D
A
D
A
D
E
R
F
I
R
R
L
K
R
D
V
L
-
E
R
G
R
S
L
E
G
V
V
A
Q
Y
L
E
Q
V
K
P
M
H
L
H
F
V
E
P
T
K
R
Y
A
D
V
I
V
P
R
G
G
Q
N
P
V
A
L
E
M
L
A
A
K
A
L
A
R
L
A
R
M
G
A
A
--------------------------------------------------------------------
6
PsiBlast_PDB
33.11
37%
324
- C4 -
3W34
1
URK_THET8
A:
[77-108]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
L
R
G
L
P
V
E
M
P
V
Y
D
F
R
A
Y
T
R
S
P
R
R
T
P
V
R
P
A
P
V
V
I
L
E
G
I
L
V
L
Y
P
K
E
L
R
D
L
M
D
L
K
V
F
V
D
A
D
A
D
E
R
F
I
R
R
L
K
R
D
V
L
-
E
R
G
R
S
L
E
G
V
V
A
Q
Y
L
E
Q
V
K
P
M
H
L
H
F
V
E
P
T
K
R
Y
A
D
V
I
V
P
R
G
G
Q
N
P
V
A
L
E
M
L
A
A
K
A
L
A
R
L
A
R
M
G
A
A
--------------------------------------------------------------------
5
PsiBlast_PDB
32.67
37%
338
- C4 -
3ASZ
1
URK_THET8
A:
[77-108]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
L
R
G
L
P
V
E
M
P
V
Y
D
F
R
A
Y
T
R
S
P
R
R
T
P
V
R
P
A
P
V
V
I
L
E
G
I
L
V
L
Y
P
K
E
L
R
D
L
M
D
L
K
V
F
V
D
A
D
A
D
E
R
F
I
R
R
L
K
R
D
V
L
-
E
R
G
R
S
L
E
G
V
V
A
Q
Y
L
E
Q
V
K
P
M
H
L
H
F
V
E
P
T
K
R
Y
A
D
V
I
V
P
R
G
G
Q
N
P
V
A
L
E
M
L
A
A
K
A
L
A
R
L
A
R
------------------------------------------------------------------------
22
Fugue
32.14
14%
259
- C3 -
1HJ0
-
TYB10_BOVIN
A:
[1-41]
--------------------------------------------------------------------------------------------------------------------------------------------------
A
D
K
P
D
L
G
E
I
N
S
F
D
K
A
K
L
K
K
T
E
T
Q
E
K
N
T
L
P
T
K
E
T
I
E
Q
E
K
Q
A
K
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
HHSearch
28.85
17%
251
- C3 -
2WWB
-
SC61G_CANFA
B:
[31-66]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
E
F
Q
K
I
A
M
A
T
A
I
G
F
A
I
M
G
F
I
G
F
F
V
K
L
I
H
I
P
I
N
N
I
I
V
G
G
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
28.73
37%
330
- C4 -
3ASY
-
URK_THET8
A:
[77-108]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
L
R
G
L
P
V
E
M
P
V
Y
D
F
R
A
Y
T
R
S
P
R
R
T
P
V
R
P
A
P
V
V
I
L
E
G
I
L
V
L
Y
P
K
E
L
R
D
L
M
D
L
K
V
F
V
D
A
D
A
D
E
R
F
I
R
R
L
K
R
D
V
L
-
E
R
G
R
S
L
E
G
V
V
A
Q
Y
L
E
Q
V
K
P
M
H
L
H
F
V
E
P
T
K
R
Y
A
D
V
I
V
P
R
G
G
Q
N
P
V
A
L
E
M
L
A
A
K
A
L
A
R
---------------------------------------------------------------------------
9
HHSearch
26.10
19%
305
- C3 -
2WW9
-
SC61G_YEAST
B:
[46-77]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
Y
T
K
I
V
K
A
V
G
I
G
F
I
A
V
G
I
I
G
Y
A
I
K
L
I
H
I
P
I
R
Y
V
I
V
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
HHSearch
24.76
30%
366
- C3 -
3MP7
-
SECE_PYRFU
B:
[29-55]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
Y
K
R
A
A
K
I
T
G
L
G
I
I
L
I
G
L
I
G
M
L
I
R
I
V
G
I
L
I
L
G
G
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
HHSearch
14.08
29%
755
- C3 -
2K1A
-
ITA2B_HUMAN
A:
[982-995]
----------------------------------------------------------------------------------------------
I
L
V
L
A
M
W
K
V
G
F
F
K
R
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
HHSearch
8.59
14%
523
- C3 -
2L8S
-
A:
[24-44]
---------------------------------------------------------------------------------------------
M
L
L
I
L
A
L
W
K
I
G
F
F
K
R
P
L
K
K
K
M
E
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
HHSearch
7.54
19%
873
- C3 -
3HE4
-
?
B:
[1-15]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
T
V
K
E
L
K
N
Y
I
Q
E
L
E
E
R
N
A
E
L
K
N
L
K
E
H
L
K
F
A
K
A
E
L
E
F
E
L
A
A
H
K
F
E
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------