@TOME V2.2
(Nov 2016)
Ref.
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : S20A2_HUMAN: (2015-12-09 )
MAMDEYLWMVILGFIIAFILAFSVGANDVANSFGTAVGSGVVTLRQACILASIFETTGSVLLGAKVGETIRKGIIDVNLYNETVETLMAGEVSAMVGSAVWQLIASFLRLPISGTHCIVGSTIGFSLVAIGTKGVQWMELVKIVASWFISPLLSGFMSGLLFVLIRIFILKKEDPVPNGLRALPVFYAATIAINVFSIMYTGAPVLGLVLPMWAIALISFGVALLFAFFVWLFVCPWMRRKITGKLQKEGALSRVSDESLSKVQEAESPVFKELPGAKANDDSTIPLTGAAGETLGTSEGTSAGSHPRAAYGRALSMTHGSVKSPISNGTFGFDGHTRSDGHVYHTVHKDSGLYKDLLHKIHIDRGPEEKPAQESNYRLLRRNNSYTCYTAAICGLPVHATFRAADSSAPEDSEKLVGDTVSYSKKRLRYDSYSSYCNAVAEAEIEAEEGGVEMKLASELADPDQPREDPAEEEKEEKDAPEVHLLFHFLQVLTACFGSFAHGGNDVSNAIGPLVALWLIYKQGGVTQEAATPVWLLFYGGVGICTGLWVWGRRVIQTMGKDLTPITPSSGFTIELASAFTVVIASNIGLPVSTTHCKVGSVVAVGWIRSRKAVDWRLFRNIFVAWFVTVPVAGLFSAAVMALLMYGILPYV
Atome Classification :
(20 SA)
.........10........20........30..------......40........50........60........70....--....80........90........100......-----.110.......120.......----130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430.......440.......450.......460.......470.......480.......490.......500.......510.......520.......530.......540.......550.......560.......570.......580.......590.......600.......610.......620.......630.......640.......650
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
M
A
M
D
E
Y
L
W
M
V
I
L
G
F
I
I
A
F
I
L
A
F
SVG
A
N
D
V
A
N
S
F
------
G
T
A
V
G
S
G
V
V
T
L
R
Q
A
C
I
L
A
S
I
F
E
TTG
S
V
L
LG
A
K
V
G
E
T
I
R
KG
I
I
--
D
V
N
L
Y
N
E
T
V
E
T
L
M
A
G
E
V
S
A
M
V
G
S
A
V
W
Q
L
I
A
S
F
L
-----RLPISGT
H
C
I
VGSTI
G
F
S
L
V
A
----IGTK
G
V
Q
W
M
E
L
V
K
I
V
A
S
W
F
I
S
P
L
L
S
G
F
M
S
G
L
L
F
V
L
I
R
I
F
I
LKKEDPVPNG
L
R
A
L
P
V
F
Y
A
A
T
I
A
I
N
V
F
S
I
M
YTGA
P
V
L
G
L
V
L
P
M
W
A
I
A
L
I
S
F
G
V
A
L
L
F
A
F
F
V
W
L
F
V
C
P
W
M
R
R
K
I
T
G
K
L
Q
KEGALSRV
S
D
E
S
L
S
K
V
Q
E
AES
P
V
F
K
ELPGAKANDDS
T
I
P
LTGAAGETLGTSEGTSAGSHP
R
A
AYG
R
A
L
SMTHGSVKSPISNGTFGFDGHTRSDG
H
V
Y
H
T
VHKDS
G
L
Y
K
D
L
L
H
K
I
HIDRGPEEKPAQES
N
Y
R
L
L
RRNNS
Y
T
C
Y
T
A
A
ICGLPV
H
A
T
F
RAADSSAPE
D
S
E
K
L
VGD
T
V
S
Y
S
K
K
RLRYD
S
Y
S
S
Y
C
N
A
V
A
E
A
E
I
EAEEG
G
V
E
M
K
L
A
S
ELADPDQPREDP
A
E
E
E
K
E
EKDAP
E
V
H
L
L
F
H
F
L
Q
V
L
T
A
C
F
G
S
FAHGGN
D
V
S
N
A
I
G
P
L
V
A
L
W
L
I
Y
KQGGVTQEAAT
P
V
W
L
L
F
YG
G
V
G
I
C
T
G
L
W
V
W
G
R
R
V
I
Q
T
MGKDLTPITPSS
G
F
T
I
E
LA
S
A
F
T
V
V
I
ASNIGLPVST
T
H
C
KV
G
S
V
V
A
V
G
W
IRSRKA
V
D
W
R
L
F
R
N
I
F
V
A
W
F
V
TV
P
V
A
G
L
F
S
A
A
V
M
A
L
L
M
Y
G
ILPYV
13
PsiBlast_PDB
79.34
25%
-110
- C4 -
4BWZ
-
?
A:
[95-252]
---------
V
A
L
P
F
L
G
G
Y
L
Y
G
L
E
I
G
F
E
T
L
P
A
L
F
L
G
T
A
L
V
A
T
S
V
G
I
T
A
R
V
L
Q
E
L
G
V
L
S
R
P
Y
S
---
R
I
I
L
G
A
A
V
I
D
D
V
L
G
L
I
V
L
A
C
V
N
G
V
A
E
T
G
Q
V
E
V
G
A
I
T
R
L
I
V
L
S
V
V
F
V
G
L
A
V
F
L
S
T
L
IA
R
L
P
L
E
--
R
L
P
V
G
S
P
L
G
F
A
L
-
A
----
L
G
------
V
G
M
A
A
L
A
A
S
I
G
L
A
P
I
V
G
A
F
L
G
G
M
L
L
S
E
V
R
E
K
Y
R
L
E
E
P
I
F
A
I
E
S
F
L
A
P
I
F
F
A
M
V
G
V
R
L
E
L
S
A
L
A
S
P
V
V
L
V
A
G
T
V
V
T
V
I
A
I
L
G
K
V
L
G
G
F
L
G
A
L
T
Q
G
V
R
S
A
L
T
V
G
C
G
M
A
P
R
G
E
V
G
L
I
V
A
A
L
G
L
K
A
G
A
V
N
E
E
E
Y
A
I
V
L
F
M
V
V
F
T
T
L
F
A
P
F
A
L
K
P
L
I
A
W
T
E
R
E
R
A
A
K
E
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
68.61
25%
54
- C4 -
3KL3
-
XYNC_BACSU
A:
[59-146]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
R
N
N
W
Y
K
E
V
E
T
A
K
S
A
V
K
H
G
A
I
V
F
A
S
P
W
N
P
P
S
D
M
V
E
T
F
N
R
N
G
D
T
S
A
K
R
L
K
Y
N
K
Y
A
A
Y
A
Q
H
L
N
D
F
V
T
F
M
K
N
N
G
V
N
L
Y
A
I
S
V
Q
N
E
P
D
Y
A
H
E
W
T
W
W
T
P
Q
E
I
L
R
F
M
R
E
N
A
G
S
I
N
A
R
V
I
A
P
E
S
F
Q
Y
L
K
N
L
S
D
P
I
L
N
D
P
Q
A
L
A
N
M
D
I
L
G
T
H
L
Y
G
T
Q
V
S
Q
F
P
Y
P
L
F
K
Q
K
G
A
G
K
D
L
W
M
T
E
V
Y
Y
P
N
S
D
T
N
S
A
D
R
W
P
E
A
L
D
V
S
Q
H
I
H
N
A
M
V
E
G
D
F
Q
A
Y
V
W
W
Y
I
R
R
S
Y
G
P
M
K
E
D
G
T
I
S
K
R
G
Y
N
M
A
H
F
S
K
F
V
R
P
G
Y
V
R
I
D
A
T
K
N
P
N
A
N
V
Y
V
S
A
Y
K
G
D
N
K
V
V
I
V
A
I
1
PsiBlast_PDB
68.37
25%
49
- C4 -
3GTN
-
XYNC_BACSU
A:
[59-146]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
R
N
N
W
Y
K
E
V
E
T
A
K
S
A
V
K
H
G
A
I
V
F
A
S
P
W
N
P
P
S
D
M
V
E
T
F
N
R
N
G
D
T
S
A
K
R
L
K
Y
N
K
Y
A
A
Y
A
Q
H
L
N
D
F
V
T
F
M
K
N
N
G
V
N
L
Y
A
I
S
V
Q
N
E
P
D
Y
A
H
E
W
T
W
W
T
P
Q
E
I
L
R
F
M
R
E
N
A
G
S
I
N
A
R
V
I
A
P
E
S
F
Q
Y
L
K
N
L
S
D
P
I
L
N
D
P
Q
A
L
A
N
M
D
I
L
G
T
H
L
Y
G
T
Q
V
S
Q
F
P
Y
P
L
F
K
Q
K
G
A
G
K
D
L
W
M
T
E
V
Y
Y
P
N
S
D
T
N
S
A
D
R
W
P
E
A
L
D
V
S
Q
H
I
H
N
A
M
V
E
G
D
F
Q
A
Y
V
W
W
Y
I
R
R
S
Y
G
P
M
K
E
D
G
T
I
S
K
R
G
Y
N
M
A
H
F
S
K
F
V
R
P
G
Y
V
R
I
D
A
T
K
N
P
N
A
N
V
Y
V
S
A
Y
K
G
D
N
K
V
V
I
V
A
I
4
PsiBlast_PDB
68.23
25%
51
- C4 -
3KL5
1
XYNC_BACSU
A:
[59-146]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
R
N
N
W
Y
K
E
V
E
T
A
K
S
A
V
K
H
G
A
I
V
F
A
S
P
W
N
P
P
S
D
M
V
E
T
F
N
R
N
G
D
T
S
A
K
R
L
K
Y
N
K
Y
A
A
Y
A
Q
H
L
N
D
F
V
T
F
M
K
N
N
G
V
N
L
Y
A
I
S
V
Q
N
E
P
D
Y
A
H
E
W
T
W
W
T
P
Q
E
I
L
R
F
M
R
E
N
A
G
S
I
N
A
R
V
I
A
P
E
S
F
Q
Y
L
K
N
L
S
D
P
I
L
N
D
P
Q
A
L
A
N
M
D
I
L
G
T
H
L
Y
G
T
Q
V
S
Q
F
P
Y
P
L
F
K
Q
K
G
A
G
K
D
L
W
M
T
E
V
Y
Y
P
N
S
D
T
N
S
A
D
R
W
P
E
A
L
D
V
S
Q
H
I
H
N
A
M
V
E
G
D
F
Q
A
Y
V
W
W
Y
I
R
R
S
Y
G
P
M
K
E
D
G
T
I
S
K
R
G
Y
N
M
A
H
F
S
K
F
V
R
P
G
Y
V
R
I
D
A
T
K
N
P
N
A
N
V
Y
V
S
A
Y
K
G
D
N
K
V
V
I
V
A
I
2
PsiBlast_PDB
68.08
25%
51
- C4 -
3KL0
1
XYNC_BACSU
A:
[59-146]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
R
N
N
W
Y
K
E
V
E
T
A
K
S
A
V
K
H
G
A
I
V
F
A
S
P
W
N
P
P
S
D
M
V
E
T
F
N
R
N
G
D
T
S
A
K
R
L
K
Y
N
K
Y
A
A
Y
A
Q
H
L
N
D
F
V
T
F
M
K
N
N
G
V
N
L
Y
A
I
S
V
Q
N
E
P
D
Y
A
H
E
W
T
W
W
T
P
Q
E
I
L
R
F
M
R
E
N
A
G
S
I
N
A
R
V
I
A
P
E
S
F
Q
Y
L
K
N
L
S
D
P
I
L
N
D
P
Q
A
L
A
N
M
D
I
L
G
T
H
L
Y
G
T
Q
V
S
Q
F
P
Y
P
L
F
K
Q
K
G
A
G
K
D
L
W
M
T
E
V
Y
Y
P
N
S
D
T
N
S
A
D
R
W
P
E
A
L
D
V
S
Q
H
I
H
N
A
M
V
E
G
D
F
Q
A
Y
V
W
W
Y
I
R
R
S
Y
G
P
M
K
E
D
G
T
I
S
K
R
G
Y
N
M
A
H
F
S
K
F
V
R
P
G
Y
V
R
I
D
A
T
K
N
P
N
A
N
V
Y
V
S
A
Y
K
G
D
N
K
V
V
I
V
A
I
5
PsiBlast_PDB
67.37
30%
204
- C4 -
1Q0V
-
VPS27_YEAST
A:
[252-321]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
Y
S
T
P
E
D
E
E
E
L
I
R
K
A
I
E
L
S
L
K
E
S
R
N
S
A
S
S
E
P
I
V
P
V
V
E
S
K
N
E
V
K
R
Q
E
I
E
E
E
E
D
P
D
L
K
A
A
I
Q
E
S
L
R
E
A
E
E
A
K
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
36
Fugue
63.93
12%
63
- C4 -
1W9R
-
?
A:
[1-119]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
S
H
M
P
E
K
K
V
A
E
A
E
K
K
V
E
E
A
K
K
K
A
E
D
Q
K
E
E
D
R
R
N
Y
P
T
N
T
Y
K
T
L
E
L
E
I
A
E
S
D
V
E
V
K
K
A
E
L
E
L
V
K
E
E
A
K
E
P
R
N
E
E
K
V
K
Q
A
K
A
E
V
E
S
K
K
A
E
A
T
R
L
E
K
I
K
T
D
R
K
K
A
E
E
E
A
K
--
R
K
A
A
E
E
D
K
V
K
E
K
P
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
62.07
31%
136
- C4 -
4UQB
1
?
A:
[121-165]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
Q
K
R
L
R
Y
D
K
Y
G
D
Y
V
Q
H
L
N
D
F
V
A
Y
M
K
S
N
G
V
D
L
Y
A
I
S
V
Q
N
E
P
D
Y
A
H
E
W
T
W
W
T
P
Q
E
M
L
R
F
M
R
D
Y
A
G
Q
I
N
C
R
V
M
A
P
E
S
F
Q
Y
L
K
N
M
S
D
P
I
L
N
D
P
Q
A
L
A
N
L
D
I
L
G
A
H
F
Y
G
T
T
V
N
N
M
P
Y
P
L
F
E
Q
K
G
A
G
K
E
L
W
M
T
E
V
Y
V
P
N
S
D
S
N
S
A
D
R
W
P
E
A
L
E
V
A
H
N
M
H
N
A
L
V
E
G
N
F
Q
A
Y
V
W
W
Y
I
R
R
S
Y
G
P
M
K
E
D
G
T
I
S
K
R
G
Y
M
M
A
H
Y
S
K
F
V
R
P
G
Y
V
R
V
D
A
T
K
N
P
T
Y
N
V
Y
L
S
A
C
K
N
K
K
D
N
S
V
V
A
V
6
PsiBlast_PDB
61.66
31%
134
- C4 -
4UQA
1
?
A:
[121-165]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
Q
K
R
L
R
Y
D
K
Y
G
D
Y
V
Q
H
L
N
D
F
V
A
Y
M
K
S
N
G
V
D
L
Y
A
I
S
V
Q
N
E
P
D
Y
A
H
E
W
T
W
W
T
P
Q
E
M
L
R
F
M
R
D
Y
A
G
Q
I
R
C
R
V
M
A
P
E
S
F
Q
Y
L
K
N
M
S
D
P
I
L
N
D
P
Q
A
L
A
N
L
D
I
L
G
A
H
F
Y
G
T
T
V
N
N
M
P
Y
P
L
F
E
Q
K
G
A
G
K
E
L
W
M
T
E
V
Y
V
P
N
S
D
S
N
S
A
D
R
W
P
E
A
L
E
V
A
H
N
M
H
N
A
L
V
E
G
N
F
Q
A
Y
V
W
W
Y
I
R
R
S
Y
G
P
M
K
E
D
G
T
I
S
K
R
G
Y
M
M
A
H
Y
S
K
F
V
R
P
G
Y
V
R
V
D
A
T
K
N
P
T
Y
N
V
Y
L
S
A
C
K
N
K
K
D
N
S
V
V
A
V
10
PsiBlast_PDB
61.58
31%
140
- C4 -
4UQC
1
?
A:
[121-165]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
Q
K
R
L
R
Y
D
K
Y
G
D
Y
V
Q
H
L
N
D
F
V
A
Y
M
K
S
N
G
V
D
L
Y
A
I
S
V
Q
N
E
P
D
Y
A
H
E
W
T
W
W
T
P
Q
E
M
L
R
F
M
R
D
Y
A
G
Q
I
N
C
R
V
M
A
P
E
S
F
Q
Y
L
K
N
M
S
D
P
I
L
N
D
P
Q
A
L
A
N
L
D
I
L
G
A
H
F
Y
G
T
T
V
N
N
M
P
Y
P
L
F
E
Q
K
G
A
G
K
E
L
W
M
T
E
V
Y
V
P
N
S
D
S
N
S
A
D
R
W
P
E
A
L
E
V
A
H
N
M
H
N
A
L
V
E
G
N
F
Q
A
Y
V
W
W
Y
I
R
R
S
Y
G
P
M
K
E
D
G
T
I
S
K
R
G
Y
M
M
A
H
Y
S
K
F
V
R
P
G
Y
V
R
V
D
A
T
K
N
P
T
Y
N
V
Y
L
S
A
C
K
N
K
K
D
N
S
V
V
A
V
11
PsiBlast_PDB
61.31
31%
134
- C4 -
4UQD
1
?
A:
[121-165]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
Q
K
R
L
R
Y
D
K
Y
G
D
Y
V
Q
H
L
N
D
F
V
A
Y
M
K
S
N
G
V
D
L
Y
A
I
S
V
Q
N
E
P
D
Y
A
H
E
W
T
W
W
T
P
Q
E
M
L
R
F
M
R
D
Y
A
G
Q
I
N
C
R
V
M
A
P
E
S
F
Q
Y
L
K
N
M
S
D
P
I
L
N
D
P
Q
A
L
A
N
L
D
I
L
G
A
H
F
Y
G
T
T
V
N
N
M
P
Y
P
L
F
E
Q
K
G
A
G
K
E
L
W
M
T
E
V
Y
V
P
N
S
D
S
N
S
A
D
R
W
P
E
A
L
E
V
A
H
N
M
H
N
A
L
V
E
G
N
F
Q
A
Y
V
W
W
Y
I
R
R
S
Y
G
P
M
K
E
D
G
T
I
S
K
R
G
Y
M
M
A
H
Y
S
K
F
V
R
P
G
Y
V
R
V
D
A
T
K
N
P
T
Y
N
V
Y
L
S
A
C
K
N
K
K
D
N
S
V
V
A
V
15
PsiBlast_PDB
61.14
37%
60
- C4 -
3V8F
1
?
A:
[302-355]
---------------------------------------------------------------------------------------------
T
L
P
L
G
A
T
I
N
M
D
G
T
A
L
Y
Q
G
V
A
T
F
F
-----
I
A
N
A
L
G
S
H
L
T
V
G
Q
Q
L
T
I
V
L
T
A
V
L
A
S
I
G
T
A
G
V
P
G
A
G
A
I
M
L
A
M
V
L
H
S
V
G
L
P
L
T
D
P
N
V
A
A
A
Y
A
C
I
L
G
I
D
A
I
L
D
M
G
R
T
M
V
N
V
T
G
D
L
T
G
T
A
I
V
A
K
T
E
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
60.96
31%
133
- C4 -
4UQ9
-
?
A:
[121-165]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
Q
K
R
L
R
Y
D
K
Y
G
D
Y
V
Q
H
L
N
D
F
V
A
Y
M
K
S
N
G
V
D
L
Y
A
I
S
V
Q
N
E
P
D
Y
A
H
E
W
T
W
W
T
P
Q
E
M
L
R
F
M
R
D
Y
A
G
Q
I
N
C
R
V
M
A
P
E
S
F
Q
Y
L
K
N
M
S
D
P
I
L
N
D
P
Q
A
L
A
N
L
D
I
L
G
A
H
F
Y
G
T
T
V
N
N
M
P
Y
P
L
F
E
Q
K
G
A
G
K
E
L
W
M
T
E
V
Y
V
P
N
S
D
S
N
S
A
D
R
W
P
E
A
L
E
V
A
H
N
M
H
N
A
L
V
E
G
N
F
Q
A
Y
V
W
W
Y
I
R
R
S
Y
G
P
M
K
E
D
G
T
I
S
K
R
G
Y
M
M
A
H
Y
S
K
F
V
R
P
G
Y
V
R
V
D
A
T
K
N
P
T
Y
N
V
Y
L
S
A
C
K
N
K
K
D
N
S
V
V
A
V
12
PsiBlast_PDB
60.91
31%
133
- C4 -
4UQE
1
?
A:
[121-165]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
Q
K
R
L
R
Y
D
K
Y
G
D
Y
V
Q
H
L
N
D
F
V
A
Y
M
K
S
N
G
V
D
L
Y
A
I
S
V
Q
N
E
P
D
Y
A
H
E
W
T
W
W
T
P
Q
E
M
L
R
F
M
R
D
Y
A
G
Q
I
N
C
R
V
M
A
P
E
S
F
Q
Y
L
K
N
M
S
D
P
I
L
N
D
P
Q
A
L
A
N
L
D
I
L
G
A
H
F
Y
G
T
T
V
N
N
M
P
Y
P
L
F
E
Q
K
G
A
G
K
E
L
W
M
T
E
V
Y
V
P
N
S
D
S
N
S
A
D
R
W
P
E
A
L
E
V
A
H
N
M
H
N
A
L
V
E
G
N
F
Q
A
Y
V
W
W
Y
I
R
R
S
Y
G
P
M
K
E
D
G
T
I
S
K
R
G
Y
M
M
A
H
Y
S
K
F
V
R
P
G
Y
V
R
V
D
A
T
K
N
P
T
Y
N
V
Y
L
S
A
C
K
N
K
K
D
N
S
V
V
A
V
16
PsiBlast_PDB
60.52
37%
51
- C4 -
3V8G
1
?
A:
[302-355]
---------------------------------------------------------------------------------------------
T
L
P
L
G
A
T
I
N
M
D
G
T
A
L
Y
Q
G
V
A
T
F
F
-----
I
A
N
A
L
G
S
H
L
T
V
G
Q
Q
L
T
I
V
L
T
A
V
L
A
S
I
G
T
A
G
V
P
G
A
G
A
I
M
L
A
M
V
L
H
S
V
G
L
P
L
T
D
P
N
V
C
A
A
Y
A
M
I
L
G
I
D
A
I
L
D
M
G
R
T
M
V
N
V
T
G
D
L
T
G
T
A
I
V
A
K
T
E
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
PsiBlast_PDB
60.43
37%
54
- C4 -
3KBC
1
?
A:
[302-355]
---------------------------------------------------------------------------------------------
T
L
P
L
G
A
T
I
N
M
D
G
T
A
L
Y
Q
G
V
A
T
F
F
-----
I
A
N
A
L
G
S
H
L
T
V
G
Q
Q
L
T
I
V
L
T
A
V
L
A
S
I
G
T
A
G
V
P
G
A
G
A
I
M
L
C
M
V
L
H
S
V
G
L
P
L
T
D
P
N
V
A
A
A
Y
A
M
I
L
G
I
D
A
I
L
D
M
G
R
T
M
V
N
V
T
G
D
L
T
G
T
A
I
V
A
K
T
E
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
60.41
31%
138
- C4 -
4CKQ
1
?
A:
[121-165]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
Q
K
R
L
R
Y
D
K
Y
G
D
Y
V
Q
H
L
N
D
F
V
A
Y
M
K
S
N
G
V
D
L
Y
A
I
S
V
Q
N
E
P
D
Y
A
H
E
W
T
W
W
T
P
Q
E
M
L
R
F
M
R
D
Y
A
G
Q
I
N
C
R
V
M
A
P
E
S
F
Q
Y
L
K
N
M
S
D
P
I
L
N
D
P
Q
A
L
A
N
L
D
I
L
G
A
H
F
Y
G
T
T
V
N
N
M
P
Y
P
L
F
E
Q
K
G
A
G
K
E
L
W
M
T
E
V
Y
V
P
N
S
D
S
N
S
A
D
R
W
P
E
A
L
E
V
A
H
N
M
H
N
A
L
V
E
G
N
F
Q
A
Y
V
W
W
Y
I
R
R
S
Y
G
P
M
K
E
D
G
T
I
S
K
R
G
Y
M
M
A
H
Y
S
K
F
V
R
P
G
Y
V
R
V
D
A
T
K
N
P
T
Y
N
V
Y
L
S
A
C
K
N
K
K
D
N
S
V
V
A
V
17
PsiBlast_PDB
59.53
37%
57
- C4 -
4IZM
1
?
A:
[302-355]
---------------------------------------------------------------------------------------------
T
L
P
L
G
A
T
I
N
M
D
G
T
A
L
Y
Q
G
V
A
T
F
F
-----
I
A
N
A
L
G
S
H
L
T
V
G
Q
Q
L
T
I
V
L
T
A
V
L
A
S
I
G
T
A
G
V
P
G
A
G
A
I
M
L
A
M
V
L
H
S
V
G
L
P
L
T
D
P
N
V
A
A
A
Y
A
M
I
L
G
I
D
A
I
L
D
M
G
R
T
M
V
N
V
T
G
D
L
T
G
T
A
I
V
A
K
T
E
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
PsiBlast_PDB
57.84
37%
53
- C4 -
4P3J
-
?
A:
[302-355]
---------------------------------------------------------------------------------------------
T
L
P
L
G
A
T
I
N
M
D
G
T
A
L
Y
Q
G
V
A
T
F
F
-----
I
A
N
A
L
G
S
H
L
T
V
G
Q
Q
L
T
I
V
L
T
A
V
L
A
S
I
G
T
A
G
V
P
G
A
G
A
I
M
L
C
M
V
L
H
S
V
G
L
P
L
T
D
P
N
V
A
A
A
Y
A
M
I
L
G
I
D
A
I
L
D
M
G
R
T
M
V
N
V
T
G
D
L
T
G
T
A
I
V
A
K
T
E
G
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
PsiBlast_PDB
56.34
37%
63
- C4 -
4P1A
-
?
A:
[302-355]
---------------------------------------------------------------------------------------------
T
L
P
L
G
A
T
I
N
M
D
G
T
A
L
Y
Q
G
V
A
T
F
F
-----
I
A
N
A
L
G
S
H
L
T
V
G
Q
Q
L
T
I
V
L
T
A
V
L
A
S
I
G
T
A
G
V
P
G
A
G
A
I
M
L
C
M
V
L
H
S
V
G
L
P
L
T
D
P
N
V
A
A
A
Y
A
M
I
L
G
I
D
A
I
L
D
M
G
R
T
M
V
N
V
T
G
D
L
T
G
T
A
I
V
A
K
T
E
G
T
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------