@TOME V2.2
(Nov 2016)
Ref.
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : S26A5_HUMAN: (2015-12-10 )
MDHAEENEILAATQRYYVERPIFSHPVLQERLHTKDKVPDSIADKLKQAFTCTPKKIRNIIYMFLPITKWLPAYKFKEYVLGDLVSGISTGVLQLPQGLAFAMLAAVPPIFGLYSSFYPVIMYCFLGTSRHISIGPFAVISLMIGGVAVRLVPDDIVIPGGVNATNGTEARDALRVKVAMSVTLLSGIIQFCLGVCRFGFVAIYLTEPLVRGFTTAAAVHVFTSMLKYLFGVKTKRYSGIFSVVYSTVAVLQNVKNLNVCSLGVGLMVFGLLLGGKEFNERFKEKLPAPIPLEFFAVVMGTGISAGFNLKESYNVDVVGTLPLGLLPPANPDTSLFHLVYVDAIAIAIVGFSVTISMAKTLANKHGYQVDGNQELIALGLCNSIGSLFQTFSISCSLSRSLVQEGTGGKTQLAGCLASLMILLVILATGFLFESLPQAVLSAIVIVNLKGMFMQFSDLPFFWRTSKIELTIWLTTFVSSLFLGLDYGLITAVIIALLTVIYRTQSPSYKVLGKLPETDVYIDIDAYEEVKEIPGIKIFQINAPIYYANSDLYSNALKRKTGVNPAVIMGARRKAMRKYAKEVGNANMANATVVKADAEVDGEDATKPEEEDGEVKYPPIVIKSTFPEEMQRFMPPGDNVHTVILDFTQVNFIDSVGVKTLAGIVKEYGDVGIYVYLAGCSAQVVNDLTRNRFFENPALWELLFHSIHDAVLGSQLREALAEQEASAPPSQEDLEPNATPATPEA
Atome Classification :
(20 SA)
.........10........20........30........40........50........60........70........80........------90........100.......110.......120....-...130.......140.......150.......160.......170.......180.......190....----...200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320-...----....330...----....340.......350.......360....----...370.......380.......390.......400.......410.......420.....--..430.......440...-------....450--.......460.......--470.......480----------..-......490.......500.......510.......520.......530.......540---.......550.......560...----..------------..570....----...580---.........590.......600.......610-........620.......630....--...640.......-650......--.660.....-.-.-670-.......680.......690.....-..700.......710........720.......730.......740..
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MDHA
E
E
N
E
I
L
A
A
T
Q
R
Y
YVERPIFS
H
P
V
L
Q
E
R
LHTKDKV
P
D
S
I
A
D
K
L
K
Q
A
FTC
T
P
K
K
I
R
N
I
I
Y
M
FL
P
I
T
KW
L
P
A
Y
K
F
K
E
Y
V
L
G
D
L
V
S
G
I
S
------
T
G
V
L
QLP
Q
G
L
A
F
A
M
L
A
AV
P
P
I
F
G
L
Y
S
S
F
Y
P
V
I
M
Y
C
FL-GTSRHISI
G
P
F
A
V
I
S
L
M
IG
G
V
A
V
R
LVPD
D
I
VIPGGVNATNGTEA
R
D
A
L
R
V
K
V
A
M
S
V
T
L
L
S
G
I
I
Q
F
C
L
G
V
C
----
R
F
G
F
V
A
I
Y
LT
E
P
L
VRG
F
T
T
A
A
A
V
H
V
F
T
S
M
L
K
Y
L
FGVKTK
R
Y
S
G
I
F
S
V
V
Y
S
T
V
A
V
L
Q
NVKNL
N
V
C
S
L
G
V
G
L
M
V
F
G
L
LLG
G
K
E
F
N
E
R
F
K
E
KLPAPI
P
L
E
F
F
A
V
V
M
GTGISAGFNLK
E
S
YN
V
D
V
V
G
TLP-LGL----LPPANPDT
S
L
----
F
H
L
V
Y
V
D
A
I
A
I
A
I
VG
F
S
V
T
I
S
M
A
K
T
L
A
N
KHG----YQVDGN
Q
E
L
I
A
L
G
L
C
N
S
I
G
S
L
F
Q
T
F
SI
S
C
S
L
S
R
S
L
V
Q
EGTG
G
K
T
Q
L
A
G
C
L
A
S
L
M
I
L
L
V
I
L
A
--
T
G
F
L
F
E
S
L
P
Q
A
V
L
S
A
I
V
I
-------
V
NLK
G
M
F
--
M
QFSDL
P
F
F
W
R
T
S
K
I
E
L
--
T
I
W
L
T
T
F
V
S
S
L
F
-----------
L
G
-
L
D
Y
G
L
I
T
A
V
I
I
A
L
L
T
V
I
YRTQSPS
Y
K
V
LGKLPET
D
V
Y
I
DID
A
Y
E
E
V
K
EIP
G
I
K
I
F
Q
INA---
P
I
Y
Y
AN
S
D
L
Y
S
N
A
L
KRKTGV
N
P
A
----
V
I
------------
M
G
A
R
R
K
A
M
R
----
K
Y
A
K
-----EVGNANMA
N
A
T
V
V
K
ADAEVDGEDATKPEEED--GEVKYP
P
I
V
I
KST
F
P
E
E
M
Q
R
FMPPG--DN
V
H
T
V
I
L
DFT
Q
V
-
N
F
I
D
SV
G
V
K
--
T
L
A
G
I
V
K
E
Y-G-D-
V
G
I
-
Y
V
Y
L
AGC
S
A
Q
V
V
N
D
L
T
R
NRFFEN
P
A
-
L
W
E
L
L
F
H
S
I
H
D
A
V
L
-
G
S
Q
L
R
E
A
L
A
E
Q
EASAPPSQEDLEPNATPATPEA
1
PsiBlast_PDB
86.12
20%
-114
- C3 -
5DA0
2
?
A:
[24-484]
----------------------------------------------------------------------------------
D
V
L
A
G
I
V
------
V
A
L
A
L
I
P
E
A
I
A
F
S
I
I
A
G
V
D
P
Q
V
G
L
Y
A
S
F
I
I
A
L
I
T
A
F
L
-
G
-------
G
R
P
G
M
I
S
A
A
T
G
A
M
A
L
L
M
T
--------
G
L
V
K
D
H
G
--------
I
Q
Y
L
F
A
A
T
V
L
T
G
V
L
Q
V
V
F
G
W
A
----
K
L
A
R
Y
L
K
F
V
P
R
S
V
M
V
G
F
V
N
A
L
A
I
L
I
F
M
A
Q
L
P
Q
F
V
G
A
N
W
Q
M
Y
A
M
V
----------------------
A
A
G
L
A
I
I
Y
L
L
------
P
L
V
F
K
A
M
---
P
S
A
L
V
A
I
V
V
L
T
V
V
A
V
V
T
G
A
D
V
K
---
T
V
G
D
M
G
T
L
P
-
T
A
L
----
P
H
F
Q
F
P
Q
V
P
L
T
F
E
T
L
A
I
I
F
P
V
A
L
T
L
S
L
V
G
L
L
E
S
L
L
T
A
Q
L
I
D
E
R
T
D
----
T
T
S
D
K
N
V
E
S
R
G
Q
G
V
A
N
I
V
T
G
F
F
G
G
M
A
G
C
A
M
I
G
Q
S
M
I
N
V
T
S
G
G
R
G
R
L
S
T
F
V
A
G
A
F
L
M
V
L
I
L
A
--
L
Q
P
L
L
V
Q
I
P
M
A
A
L
V
A
V
M
M
-------
V
V
A
I
S
T
F
DW
G
S
L
R
----
F
P
K
G
E
T
V
V
M
L
A
T
V
A
V
T
V
F
T
H
D
L
S
-----------
L
G
-
V
L
I
G
V
V
-------
L
S
A
L
F
F
A
R
K
V
S
--------------
Q
L
S
Q
V
T
P
V
D
E
V
D
G
T
R
T
Y
R
V
R
G
---
Q
L
F
F
V
S
T
H
D
F
L
H
Q
F
D
F
T
H
P
A
R
R
V
----
V
I
D
LSD
A
H
F
WD
G
S
A
V
G
A
L
D
K
V
M
L
----
K
F
M
R
Q
G
T
S
V
E
L
R
G
L
N
A
A
S
A
T
L
V
E
R
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------
26
Fugue
82.21
91%
-117
- C3 -
3LLO
1
A:
[1-143]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
P
S
Y
T
V
L
G
Q
L
P
D
T
D
V
Y
I
D
I
D
A
Y
E
E
V
K
E
I
P
G
I
K
I
F
Q
I
N
A
---
P
I
Y
Y
A
N
S
D
L
Y
S
S
A
N
I
H
---------------------------------------------------------------------------------------------------------------
T
V
I
L
D
F
T
Q
V
-
N
F
M
D
S
V
G
V
K
--
T
L
A
G
I
V
K
E
Y
-
G
-
D
-
V
G
I
-
Y
V
Y
L
A
G
C
S
A
Q
V
V
N
D
L
T
S
N
R
F
F
E
N
P
A
-
L
K
E
L
L
F
H
S
I
H
D
A
V
L
-
G
S
Q
V
R
E
A
--------------------------
27
Fugue
78.58
21%
-99
- C3 -
5DA0
2
?
A:
[14-484]
------------------------------------------------------------------------
Q
R
E
W
F
A
N
P
R
K
D
V
L
A
G
I
V
------
V
A
L
A
L
I
P
E
A
I
A
F
S
I
I
A
G
V
D
P
Q
V
G
L
Y
A
S
F
I
I
A
L
I
T
A
F
L
-
G
G
R
P
G
M
I
S
A
A
T
G
A
M
A
L
L
M
T
G
L
V
-----------------------
K
D
H
G
I
Q
Y
L
F
A
A
T
V
L
T
G
V
L
Q
V
V
F
G
W
A
----
K
L
A
R
Y
L
K
F
V
P
R
S
V
M
V
G
F
V
N
A
L
A
I
L
I
F
M
A
Q
L
P
Q
F
V
G
--------------------
A
N
W
Q
M
Y
A
M
V
A
A
G
L
A
I
I
Y
L
L
P
L
V
-----
F
K
A
M
P
S
A
L
V
A
I
V
V
L
T
V
V
A
V
V
T
G
A
D
V
K
---------
T
V
G
D
M
G
T
L
P
-
T
A
L
PHFQ
F
P
Q
V
P
L
T
F
E
T
----
L
A
I
I
F
P
V
A
L
T
L
S
L
V
G
L
L
E
S
L
L
T
A
Q
L
I
D
E
R
T
D
----
T
T
S
D
K
N
V
E
S
R
G
Q
G
V
A
N
I
V
T
G
F
F
G
G
M
A
G
C
A
M
I
G
Q
S
M
I
N
V
T
S
G
G
R
G
R
L
S
T
F
V
A
G
A
F
L
M
V
L
I
L
A
--
L
Q
P
L
L
V
Q
I
P
M
A
A
L
V
A
V
M
M
-------
V
V
A
I
S
T
F
---
D
W
G
S
L
R
F
----
P
K
G
E
T
--
V
V
M
L
A
T
V
A
V
T
V
F
-----------
T
H
D
L
S
L
G
V
L
I
G
V
V
L
S
A
L
F
F
A
R
K
V
S
Q
-----
L
S
Q
V
T
P
V
D
E
V
D
G
T
R
T
Y
R
V
R
G
Q
L
F
F
V
S
T
H
D
F
L
H
---
Q
F
D
F
T
H
P
A
R
R
V
V
I
D
L
S
D
A
H
F
W
D
G
----
S
A
------------
V
G
A
L
D
K
V
M
L
----
K
F
M
R
Q
G
T
S
V
E
L
R
G
L
N
A
A
S
A
T
L
V
E
R
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------
15
HHSearch
53.65
15%
-77
- C3 -
2KA5
-
Y1081_THEMA
A:
[4-124]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
K
I
H
H
H
H
H
H
M
F
P
Y
K
I
V
D
D
V
V
I
L
M
P
N
K
---
E
L
N
I
E
N
A
H
L
F
K
K
W
V
F
D
E
F
L
-----------------------------------------------------------------------------------------------------
N
--
K
G
Y
N
K
I
F
L
V
L
S
D
V
-
E
S
I
D
S
F
S
L
G
--
V
I
V
N
I
L
K
S
I
-
S
-
S
-
S
G
G
-
F
F
A
L
V
S
P
N
E
K
V
E
R
V
L
S
L
T
N
L
D
R
I
-----
V
K
I
Y
D
T
I
S
E
A
M
E
-
E
V
R
R
K
----------------------------
20
HHSearch
53.02
15%
-68
- C3 -
3T6O
-
?
A:
[10-120]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
H
E
A
Q
V
T
V
I
S
F
P
A
VFQ
R
L
R
E
T
E
V
E
Q
I
A
S
T
F
L
A
A
M
Q
-----------------------------------------------------------------------------------------------------
G
--
A
Q
P
R
K
V
L
I
D
L
E
G
V
-
E
F
F
G
S
S
F
I
E
--
L
L
V
R
G
W
K
R
I
-
K
-
E
D
Q
Q
G
-
V
F
A
L
C
S
V
S
P
Y
C
V
E
V
L
Q
V
T
H
I
D
E
V
-----
W
P
R
Y
S
T
K
Q
E
A
L
L
-
A
M
A
------------------------------
12
HHSearch
52.82
11%
-106
- C3 -
3QE7
2
URAA_ECOLI
A:
[12-410]
-----------------------------------------------------------------------------
P
P
L
L
Q
T
I
P
L
S
L
Q
H
L
F
A
M
F
G
A
T
V
L
V
P
V
L
F
H
------
I
N
P
A
T
V
L
L
F
N
G
I
G
T
L
L
Y
L
F
I
C
K
G
K
I
P
A
Y
L
G
S
S
F
A
F
I
S
P
V
L
L
L
L
P
------------------------
L
G
Y
E
V
A
L
G
G
F
I
M
C
G
V
L
F
C
L
V
S
F
I
V
K
K
A
G
T
G
W
L
D
V
L
F
P
P
A
A
M
G
A
I
V
A
V
I
G
L
E
L
A
G
V
A
A
G
M
A
G
L
L
P
--
A
-
E
G
---------------
Q
T
P
D
S
K
T
I
I
I
S
I
T
T
L
A
V
T
V
L
G
S
V
L
F
R
G
-----
F
L
A
I
I
P
I
L
I
G
V
L
V
G
Y
A
L
S
F
A
M
G
I
V
---
D
T
T
P
I
I
N
A
H
W
F
A
L
----
P
T
L
Y
T
P
R
F
E
------
W
F
A
I
L
T
I
L
P
A
A
L
V
V
I
A
E
H
V
G
H
L
V
V
T
A
N
I
V
K
KDLL
R
D
P
G
L
H
R
S
M
F
A
N
G
L
S
T
V
I
S
G
F
F
G
S
T
P
N
T
T
Y
G
E
N
I
G
V
M
A
I
T
R
V
Y
S
T
W
V
I
G
G
A
A
I
F
A
I
L
L
S
C
V
G
K
L
A
A
A
I
Q
M
I
P
L
P
V
M
G
G
V
S
L
L
L
Y
G
V
I
G
A
S
G
I
R
V
L
--
I
E
--
S
K
V
D
Y
N
--
K
A
Q
N
L
--
I
L
T
S
V
I
L
I
I
G
V
S
GAKVNIGAAEL
K
G
-
M
A
L
A
T
I
V
G
I
G
L
S
L
I
F
K
L
I
S
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
HHSearch
51.37
14%
-47
- C3 -
1H4X
1
SP2AA_LYSSH
A:
[8-112]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
T
R
E
T
V
V
I
R
L
F
G
---
E
L
D
H
H
A
V
E
Q
I
R
A
K
I
S
T
A
I
F
-----------------------------------------------------------------------------------------------------
Q
--
G
A
V
T
T
I
I
W
N
F
E
R
L
-
S
F
M
D
S
S
G
V
G
--
L
V
L
G
R
M
R
E
L
-
E
-
A
-
V
A
G
-
R
T
I
L
L
N
P
S
P
T
M
R
K
V
F
Q
F
S
G
L
G
P
W
-----
M
-
M
D
A
T
E
E
E
A
I
D
-
R
V
R
------------------------------
16
HHSearch
51.12
16%
-80
- C3 -
3NY7
2
?
A:
[14-118]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
P
D
D
V
L
V
L
R
V
I
G
---
P
L
F
F
A
A
A
E
G
L
F
T
D
L
E
S
R
L
---------------------------------------------------------------------------------------------------------
E
G
K
R
I
V
I
L
K
W
D
A
V
-
P
V
L
D
A
G
G
L
D
--
A
F
Q
R
F
V
K
R
L
-
P
---
E
G
C
-
E
L
R
V
C
N
V
E
F
Q
P
L
R
T
M
A
R
A
G
I
Q
P
I
P
--
G
R
L
A
F
F
P
N
R
R
A
A
M
A
-
D
L
-------------------------------
19
HHSearch
51.04
20%
-67
- C3 -
1SBO
-
Y1442_THEMA
A:
[9-110]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
E
Q
D
D
K
A
I
V
R
V
Q
G
---
D
I
D
A
Y
N
S
S
E
L
K
E
Q
L
R
N
F
I
S
-----------------------------------------------------------------------------------------------------
T
--
T
S
K
K
K
I
V
L
D
L
S
S
V
-
S
Y
M
D
S
A
G
L
G
--
T
L
V
V
I
L
K
D
A
-
K
-
I
-
N
G
K
-
E
F
I
L
S
S
L
K
E
S
I
S
R
I
L
K
L
T
H
L
D
K
I
-----
F
K
I
T
D
T
V
E
E
A
------------------------------------
17
HHSearch
50.77
14%
-70
- C3 -
1TH8
-
SP2AA_GEOSE
B:
[8-114]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
V
K
Q
D
V
L
I
V
R
L
S
G
---
E
L
D
H
H
T
A
E
E
L
R
E
Q
V
T
D
V
L
E
-----------------------------------------------------------------------------------------------------
N
--
R
A
I
R
H
I
V
L
N
L
G
Q
L
-
T
F
M
D
S
S
G
L
G
--
V
I
L
G
R
Y
K
Q
I
-
K
-
N
-
V
G
G
-
Q
M
V
V
C
A
V
S
P
A
V
K
R
L
F
D
M
S
G
L
F
K
I
-----
I
R
V
E
A
D
E
Q
F
A
L
Q
-
A
L
G
V
A
----------------------------
14
HHSearch
43.92
19%
-9
- C3 -
2KLN
-
?
A:
[1-124]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
H
D
I
D
D
Y
P
Q
A
K
R
V
P
G
L
V
V
Y
R
Y
D
A
---
P
L
C
F
A
N
A
E
D
F
R
R
R
A
L
T
V
V
D
Q
---------------------------------------------------------------------------------------------------
D
P
--
G
Q
V
E
W
F
V
L
N
A
E
S
N
-
V
E
V
D
L
T
A
L
D
--
A
L
D
Q
L
R
T
E
L
-
L
-
R
-
R
G
I
-
V
F
A
M
A
R
V
K
Q
D
L
R
E
S
L
R
A
A
S
L
L
D
K
I
--
G
E
D
H
I
F
M
T
L
P
T
A
V
Q
-
A
F
R
R
R
----------------------------
29
Fugue
34.34
20%
72
- C3 -
2KLN
-
?
A:
[1-124]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
H
D
I
D
D
Y
P
Q
A
K
R
V
P
G
L
V
V
Y
R
Y
D
A
---
P
L
C
F
A
N
A
E
D
F
R
R
R
A
L
T
V
V
D
Q
D
P
G
Q
V
E
W
F
V
------------
L
N
A
E
S
N
V
E
V
DLTA
L
D
A
L
-----
D
Q
L
R
T
E
L
L
R
R
G
I
V
F
A
M
A
R
V
K
Q
D
L
R
E
S
L
R
A
A
S
--
L
L
D
K
I
G
E
D
H
I
F
M
T
L
P
T
A
V
Q
A
F
R
R
R
------------------------------------------------------------------------------------------------------------------------
21
HHSearch
34.22
16%
30
- C3 -
3OIZ
-
?
A:
[398-478]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
K
D
G
R
E
R
I
Y
R
V
E
G
---
Q
L
F
Y
A
S
V
E
D
F
M
A
A
F
D
F
R
E
----------------------------------------------------------------------------------------------------------
A
L
D
R
V
V
I
D
V
S
R
A
-
H
I
W
D
I
S
S
V
Q
--
A
L
D
M
A
V
L
K
F
-
R
-
R
-
E
G
A
-
E
V
R
I
V
G
M
N
E
A
S
E
T
M
V
-----------------------------------------------------------
22
HHSearch
33.10
27%
49
- C3 -
3AGD
-
?
A:
[402-446]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
P
I
R
T
V
V
L
N
L
A
R
V
-
D
R
I
D
D
V
G
R
R
--
L
I
A
E
G
V
R
R
L
-
Q
-
A
-
D
G
V
-
R
V
E
V
E
D
P
E
R
I
L
P
L
-------------------------------------------------------------
23
HHSearch
31.92
14%
-3
- C3 -
2OOK
2
?
A:
[53-126]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
V
S
L
F
L
D
A
T
E
L
-
D
G
W
D
L
R
A
A
----
W
D
D
L
K
L
G
L
K
H
-
K
-
S
E
F
E
R
V
A
I
L
G
N
K
D
W
Q
E
W
A
A
K
I
G
S
W
F
I
-
A
--
G
E
I
K
Y
F
E
D
E
D
D
A
L
K
-
W
L
R
Y
-----------------------------
25
HHSearch
30.70
13%
-7
- C3 -
2Q3L
4
?
A:
[53-126]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
I
V
A
L
I
D
I
T
E
L
-
D
G
L
S
L
H
A
A
----
W
D
D
L
K
L
G
L
-
K
H
G
-
K
E
F
K
R
V
A
I
I
G
Q
G
-
E
L
Q
E
W
A
T
R
--
V
A
N
W
F
T
P
G
E
F
K
F
F
E
D
K
R
D
A
L
D
-
W
L
C
------------------------------
34
Fugue
30.48
9%
5
- C3 -
4H9N
-
DAXX_HUMAN
C:
[5-209]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
G
S
R
R
Q
I
Q
R
L
E
Q
L
L
A
L
Y
V
A
E
----
I
R
------------
R
L
Q
E
K
E
L
D
L
----
S
E
L
D
-----
D
P
D
S
A
Y
L
Q
E
A
R
L
K
R
K
L
I
R
L
F
G
R
L
C
E
L
K
D
C
S
S
LT
G
R
V
I
E
Q
R
I
P
Y
R
G
T
R
Y
P
E
V
N
R
R
I
E
R
L
I
N
K
P
G
P
D
T
F
P
D
Y
G
D
V
L
R
A
V
E
K
A
A
A
R
--
H
S
L
G
L
P
R
Q
Q
-
L
-
Q
-
L
M
A
-
Q
D
A
F
R
D
V
G
I
R
L
Q
E
R
R
H
L
D
L
I
Y
N
F
G
C
-
H
L
T
D
D
Y
R
P
G
V
D
P
A
L
S
D
P
V
L
A
R
R
L
R
E
N
R
S
L
A
M
S
R
L
D
E
V
I
S
K
Y
A
M
L
Q
D
K
S
10
PsiBlast_PDB
29.19
27%
25
- C3 -
2B30
-
?
A:
[100-176]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
I
V
Y
--
D
Q
I
G
Y
T
L
L
D
E
T
I
E
T
D
V
Y
A
E
L
I
S
Y
L
V
E
K
N
L
V
N
Q
T
I
F
H
R
G
E
---
S
N
Y
V
T
E
D
N
K
Y
A
D
F
L
Q
K
M
Y
S
E
N
R
S
----
I
I
------------
I
--
R
H
N
E
M
L
----
K
Y
R
T
-----
M
N
K
L
M
I
V
L
D
P
S
E
S
K
T
V
I
G
N
L
K
Q
K
F
K
N
K
L
T
I
F
--
T
T
Y
N
G
H
A
E
V
T
K
L
G
H
D
K
Y
T
G
I
N
Y
L
L
K
--
H
Y
N
I
S
N
D
Q
V
L
V
V
G
-
D
A
E
N
D
I
A
M
L
--
S
N
F
K
Y
S
F
A
V
-
A
-
N
-
A
T
D
-
S
A
K
S
H
A
K
C
V
L
P
V
S
H
R
E
G
A
V
A
Y
L
L
K
K
-
V
F
D
L
K
-------------------------------------------
28
Fugue
27.38
17%
129
- C3 -
2KRU
-
A:
[1-63]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
G
E
L
S
W
T
A
E
A
E
K
M
L
G
K
V
P
F
----
F
V
------------
R
K
K
V
R
K
N
T
D
----
N
Y
A
R
-----
E
I
G
E
P
V
V
T
A
D
V
F
R
K
A
K
E
H
L
G
G
L
E
H
H
H
H
H
H
----------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
27.02
26%
59
- C4 -
2JKA
1
SUSB_BACTN
A:
[583-645]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
S
P
L
Q
M
A
A
D
I
P
E
N
Y
E
R
F
M
D
A
F
--
Q
F
I
K
D
V
A
L
D
W
D
E
T
-
N
Y
L
E
A
E
P
G
E
Y
I
T
I
A
R
K
A
K
D
T
-
D
-
D
-------
W
Y
V
G
C
T
A
G
E
N
G
H
T
S
K
L
V
F
D
F
L
T
P
-
G
K
Q
Y
I
A
T
V
Y
A
D
A
K
D
-
A
D
W
K
E
N
P
Q
A
Y
T
I
K
K
G
I
L
T
N
K
S
K
L
N
L
H
A
A
N
G
G
G
Y