@TOME V2.2
(Nov 2016)
Ref.
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : S26A8_HUMAN: (2015-12-10 )
MAQLERSAISGFSSKSRRNSFAYDVKREVYNEETFQQEHKRKASSSGNMNINITTFRHHVQCRCSWHRFLRCVLTIFPFLEWMCMYRLKDWLLGDLLAGISVGLVQVPQGLTLSLLARQLIPPLNIAYAAFCSSVIYVIFGSCHQMSIGSFFLVSALLINVLKVSPFNNGQLVMGSFVKNEFSAPSYLMGYNKSLSVVATTTFLTGIIQLIMGVLGLGFIATYLPESAMSAYLAAVALHIMLSQLTFIFGIMISFHAGPISFFYDIINYCVALPKANSTSILVFLTVVVALRINKCIRISFNQYPIEFPMELFLIIGFTVIANKISMATETSQTLIDMIPYSFLLPVTPDFSLLPKIILQAFSLSLVSSFLLIFLGKKIASLHNYSVNSNQDLIAIGLCNVVSSFFRSCVFTGAIARTIIQDKSGGRQQFASLVGAGVMLLLMVKMGHFFYTLPNAVLAGIILSNVIPYLETISNLPSLWRQDQYDCALWMMTFSSSIFLGLDIGLIISVVSAFFITTVRSHRAKILLLGQIPNTNIYRSINDYREIITIPGVKIFQCCSSITFVNVYYLKHKLLKEVDMVKVPLKEEEIFSLFNSSDTNLQGGKICRCFCNCDDLEPLPRILYTERFENKLDPEASSINLIHCSHFESMNTSQTASEDQVPYTVSSVSQKNQGQQYEEVEEVWLPNNSSRNSSPGLPDVAESQGRRSLIPYSDASLLPSVHTIILDFSMVHYVDSRGLVVLRQICNAFQNANILILIAGCHSSIVRAFERNDFFDAGITKTQLFLSVHDAVLFALSRKVIGSSELSIDESETVIRETYSETDKNDNSRYKMSSSFLGSQKNVSPGFIKIQQPVEEESELDLELESEQEAGLGLDLDLDRELEPEMEPKAETETKTQTEMEPQPETEPEMEPNPKSRPRAHTFPQQRYWPMYHPSMASTQSQTQTRTWSVERRRHPMDSYSPEGNSNEDV
Atome Classification :
(20 SA)
.........10........20........30........40........50........60........70........80........90.---.......100-----........110.......120.......130.......140........150.......160.......170.......180.......190.......200.......210...----....220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340........-350.......360.......370.......380..----.....390.......400.......410.......420.......430.......440...--....450.......460..-------.....470.......480.......490.......-----------500........510........520.......530.......540.......550.......560----........570.......580......----.590.......600.......610.......620.......630.......640.......650.......660.......670.......680.......690.......700.......-----710.......720.........730.......740.......750........760.......770.......780.......790.......800.......810.......820.......830.......840--.......850.......860.......870.......880.......890.......900.......910...-....920.......930.......940.......950.......960.......970
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MA
Q
L
E
R
S
A
ISGFSSKSRRNS
F
A
Y
D
V
K
R
E
VY
N
E
E
T
F
Q
Q
E
H
K
R
KASSSG
N
M
N
I
N
I
T
T
F
R
H
H
V
Q
C
R
C
S
W
H
R
F
L
R
C
V
L
T
I
F
P
F
L
E
W
M
C
M
Y
R
L
K
D
W
L
---
L
G
D
L
L
A
G
I
S
------
V
G
L
VQVPQG
L
T
L
S
L
L
A
R
QLIPP
L
N
I
A
Y
A
A
F
C
S
S
V
I
Y
V
I
F-GSCHQM
S
I
G
S
F
F
L
V
S
A
L
L
I
N
V
LKVSPFNN
G
Q
L
V
M
G
S
F
V
K
NEFSAP
S
Y
L
MGYNK
S
L
S
V
V
A
T
T
T
F
L
T
G
I
I
Q
L
I
M
G
V
L
----
G
L
G
F
I
A
T
YL
P
E
S
A
M
S
A
Y
L
A
A
V
A
L
H
I
M
L
S
Q
L
T
F
I
F
G
I
M
I
SFHA
G
P
I
S
F
F
Y
D
I
I
N
Y
C
VALPKANS
T
S
I
L
V
F
L
T
V
V
V
A
L
RIN
K
C
I
R
I
SFNQYP
I
E
F
P
M
E
L
F
L
I
I
G
F
T
V
I
A
N
K
I
SMAT
E
T
S
Q
T
L
I
D
MI
P
-
Y
S
FLLPVTP-
D
F
S
L
L
P
K
I
I
L
Q
A
F
S
L
S
L
V
S
S
F
L
L
I
F
L
G
K
K
I
A
S
L
HN----YSVNSNQ
D
L
I
A
I
G
L
C
N
V
V
S
S
F
F
R
S
C
V
F
T
G
A
I
A
R
T
I
I
QDKSG
G
R
Q
Q
F
A
S
L
V
G
A
G
V
M
L
L
L
M
V
K
--M
G
H
F
F
Y
TL
P
N
A
V
L
A
G
I
I
L
S
-------
N
V
I
P
Y
L
E
T
I
S
N
L
P
S
L
W
R
QDQY
D
C
A
L
W
M
MTFSS
S
I
F
-----------
L
-G
L
D
I
G
L
I
I
S
V
V
-
S
A
F
F
I
T
T
V
RSHR
A
K
I
L
L
L
GQIPN
T
N
I
Y
R
S
I
N
D
Y
R
E
I
ITIP
G
V
K
I
F
Q
C
C
SS-----
I
T
F
V
N
V
Y
Y
L
K
H
K
L
L
K
E
VDMVKVPL
K
E
E
----
E
I
F
S
L
FNSSDTNLQGG
K
I
C
R
C
F
CNCDDLE
P
L
P
R
I
L
Y
T
E
R
FENKLDPEAS
S
I
N
L
I
H
CSHFESMNTSQTASEDQV
P
Y
T
V
S
S
V
SQKNQG
Q
Q
Y
E
E
V
E
E
VWLPNNSSRNSSPGLP
D
V
A
E
SQGRRSL-----IPYSD
A
S
LLP
S
--
V
H
T
I
I
L
D
F
S
M
V
H
Y
VDS
R
G
L
V
V
L
R
Q
I
C
N
A
FQN-A
N
I
L
I
L
I
AGC
H
S
S
I
V
R
A
F
ERNDFFDAGI
T
K
T
Q
L
F
L
S
V
H
D
A
V
L
F
A
L
S
R
K
VIGSSELSID
E
S
E
T
V
I
R
E
T
Y
SETDKNDNS
R
Y
K
M
S
S
S
FLGSQKN--VSPG
F
I
K
I
QQPVEEESEL
D
L
E
LESEQEAGLGLDLDLDRELEPEMEPKAETETKTQTEMEPQPETEPEMEPNPK-SRPRAHTFPQQRYWPMYHPSMASTQSQTQTR
T
W
S
V
E
R
RRHPMDSYSPEGNSNEDV
21
Fugue
94.86
21%
-116
- C1 -
5DA0
2
?
A:
[14-484]
---------------------------------------------------------------------------------------
Q
R
E
W
F
AN
P
R
K
D
V
L
A
G
I
V
------
V
A
L
A
L
I
P
E
A
I
A
F
S
I
I
A
G
--
V
D
P
Q
V
G
L
Y
A
S
F
I
I
A
L
I
T
A
F
L
-
G
G
R
P
G
M
I
S
A
A
T
G
A
M
A
L
L
M
T
G
L
V
K
----------------------------
D
H
G
I
Q
Y
L
F
A
A
T
V
L
T
G
V
L
Q
V
V
F
G
W
A
----
K
L
A
R
Y
L
K
F
V
P
R
S
V
M
V
G
F
V
N
A
L
A
I
L
I
F
M
A
Q
----------------------------
L
P
Q
F
V
G
A
N
W
Q
M
Y
A
M
V
A
A
G
L
A
I
I
Y
L
L
P
L
V
F
K
A
M
P
S
A
L
V
A
I
V
V
L
T
V
V
A
V
V
T
G
A
D
V
K
T
V
G
D
M
G
-
T
L
P
T
A
L
P
-
H
F
Q
F
P
Q
V
P
L
-
T
F
E
T
L
A
I
I
F
P
V
A
L
T
L
S
L
V
G
L
L
E
S
L
L
T
A
Q
L
I
D
E
R
T
D
----
T
T
S
D
K
N
V
E
S
R
G
Q
G
V
A
N
I
V
T
G
F
F
G
G
M
A
G
C
A
M
I
G
Q
S
M
I
N
V
T
S
G
G
R
G
R
L
S
T
F
V
A
G
A
F
L
M
V
L
I
L
A
--
L
Q
P
L
L
V
Q
I
P
M
A
A
L
V
A
V
M
M
V
-------
V
A
I
S
T
F
D
W
G
S
L
R
F
P
K
G
E
T
V
V
M
L
A
T
V
A
V
T
V
F
T
H
D
L
S
-----------
L
-
G
V
L
I
G
V
V
L
S
----
A
L
F
F
A
R
K
V
S
Q
L
S
Q
V
T
P
V
D
E
V
D
G
T
R
T
Y
R
V
R
G
Q
L
F
F
V
S
T
H
D
F
L
H
Q
F
D
F
T
H
P
AR
R
V
V
I
D
L
S
D
A
H
F
W
D
G
S
A
V
G
A
L
D
K
V
M
L
K
F
M
R
Q
G
T
S
V
E
L
R
G
L
N
A
A
S
A
T
L
V
E
R
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
87.60
20%
-117
- C1 -
5DA0
2
?
A:
[24-410]
-------------------------------------------------------------------------------------------------
D
V
L
A
G
I
V
------
V
A
L
A
L
I
P
E
A
I
A
F
S
I
I
A
G
--
V
D
P
Q
V
G
L
Y
A
S
F
I
I
A
L
I
T
A
F
L
-
G
G
R
P
G
M
I
S
A
A
T
G
A
M
A
L
L
M
T
G
L
V
K
----
D
H
G
-------
I
Q
Y
L
F
A
A
-----------------
T
V
L
T
G
V
L
Q
V
V
F
G
W
A
----
K
L
A
R
Y
L
K
F
V
P
R
S
V
M
V
G
F
V
N
A
L
A
I
L
I
F
M
A
Q
L
----------------------------
P
Q
F
V
G
A
N
W
Q
M
Y
A
M
V
A
A
G
L
A
I
I
Y
L
L
P
L
V
F
K
A
M
P
S
A
L
V
A
I
V
V
L
T
V
V
A
V
V
T
G
A
D
V
K
T
V
G
D
M
G
-
T
L
P
T
A
L
P
-
H
-
F
Q
F
P
Q
V
P
L
T
F
E
T
L
A
I
I
F
P
V
A
L
T
L
S
L
V
G
L
L
E
S
L
L
T
A
Q
L
I
D
E
R
T
D
----
T
T
S
D
K
N
V
E
S
R
G
Q
G
V
A
N
I
V
T
G
F
F
G
G
M
A
G
C
A
M
I
G
Q
S
M
I
N
V
T
S
G
G
R
G
R
L
S
T
F
V
A
G
A
F
L
M
V
L
I
L
A
--
L
Q
P
L
L
V
Q
I
P
M
A
A
L
V
A
V
M
M
V
-------
V
A
I
S
T
F
D
W
-
G
S
L
R
----
F
P
K
G
E
T
V
V
M
L
A
T
V
A
V
T
V
F
-----------
T
H
D
L
S
L
G
V
L
I
G
V
V
L
S
A
L
F
F
A
R
K
V
S
Q
L
S
Q
V
T
P
V
D
E
V
D
G
T
R
T
Y
R
V
R
G
Q
L
F
F
V
S
T
H
D
F
L
H
Q
F
D
F
T
H
P
-----
A
R
R
V
V
I
D
L
S
D
A
H
F
W
D
G
S
A
V
G
A
L
D
K
V
M
L
----
K
F
M
R
Q
G
T
S
V
E
L
R
G
L
N
A
A
S
A
T
L
V
E
R
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
HHSearch
65.17
16%
-127
- C1 -
3QE7
2
URAA_ECOLI
A:
[14-410]
-------------------------------------------------------------------------------------------
L
---
L
Q
T
I
P
L
S
L
Q
H
L
F
A
M
F
G
A
T
V
L
V
P
V
L
F
H
--------
I
N
P
A
T
V
L
L
F
N
G
I
G
T
L
L
Y
L
F
I
C
K
G
K
I
P
A
Y
L
G
S
S
F
A
F
I
S
P
V
L
L
L
L
-----------------------------
P
L
G
Y
E
V
A
L
G
G
F
I
M
C
G
V
L
F
C
L
V
S
F
I
V
K
K
A
G
T
G
W
L
D
V
L
F
P
P
A
A
M
G
A
I
V
A
V
I
G
L
E
L
A
G
V
A
A
G
M
A
G
L
L
P
A
---
E
G
---------------
Q
T
P
D
S
K
T
I
I
I
S
I
T
T
L
A
V
T
V
L
G
S
V
L
---
F
R
-
G
F
L
A
I
I
P
I
L
I
G
V
L
V
G
Y
A
L
S
F
A
M
G
I
V
D
---
T
T
P
I
I
N
A
H
W
F
A
L
P
T
L
Y
T
P
-
R
F
E
--
W
F
A
I
L
T
I
L
P
A
A
L
V
V
I
A
E
H
V
G
H
L
V
V
T
A
N
I
V
K
KDLL
R
D
P
G
L
H
R
S
M
F
A
N
G
L
S
T
V
I
S
G
F
F
G
S
T
P
N
T
T
Y
G
E
N
I
G
V
M
A
I
T
R
V
Y
S
T
W
V
I
G
G
A
A
I
F
A
I
L
L
S
C
V
G
K
L
A
A
A
I
Q
M
I
P
L
P
V
M
G
G
V
S
L
L
L
Y
G
V
I
G
A
S
G
I
R
V
L
I
E
S
K
-
V
-
D
Y
N
--
K
A
Q
N
L
I
L
T
S
V
I
L
I
I
G
V
S
GAKVNIGAAEL
K
-
G
M
A
L
A
T
I
V
G
I
G
-
L
S
L
I
F
K
L
I
S
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
Fugue
57.63
31%
-55
- C2 -
3LLO
1
A:
[1-143]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
P
S
Y
T
V
L
G
Q
L
P
D
T
D
V
Y
I
D
I
D
A
Y
E
E
V
K
E
I
P
G
I
K
I
F
Q
I
NAP
I
Y
Y
A
N
S
D
L
Y
S
S
AN
I
H
T
V
I
L
D
F
T
Q
V
N
F
M
D
S
V
G
V
K
T
L
A
G
I
V
K
E
Y
G
D
-
V
G
I
Y
V
Y
L
A
G
C
S
A
Q
V
V
N
D
L
T
S
N
R
F
F
E
N
P
A
L
K
E
L
L
F
H
S
I
H
D
A
V
L
G
S
Q
V
R
E
A
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
56.11
37%
-74
- C2 -
3LLO
1
A:
[63-142]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
--
I
H
T
V
I
L
D
F
T
Q
V
N
F
M
D
S
V
G
V
K
T
L
A
G
I
V
K
E
Y
G
D
-
V
G
I
Y
V
Y
L
A
G
C
S
A
Q
V
V
N
D
L
T
S
N
R
F
F
E
N
P
A
L
K
E
L
L
F
H
S
I
H
D
A
V
L
G
S
Q
V
R
E
A
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
HHSearch
47.23
14%
-30
- C2 -
3NY7
2
?
A:
[46-118]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
R
I
V
I
L
K
W
D
A
V
P
V
L
D
A
G
G
L
D
A
F
Q
R
F
V
K
R
L
P
--
E
G
C
E
L
R
V
C
N
V
E
F
Q
P
L
R
T
M
A
R
A
G
I
Q
P
-
I
P
G
R
L
A
F
F
P
N
R
R
A
A
M
A
D
L
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
HHSearch
46.68
15%
-65
- C2 -
2KA5
-
Y1081_THEMA
A:
[52-124]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
N
K
I
F
L
V
L
S
D
V
E
S
I
D
S
F
S
L
G
V
I
V
N
I
L
K
S
I
S
S
-
S
G
G
F
F
A
L
V
S
P
N
E
K
V
E
R
V
L
S
L
T
N
L
D
R
----
I
V
K
I
Y
D
T
I
S
E
A
M
E
E
V
R
R
K
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
HHSearch
46.61
17%
-59
- C2 -
1TH8
-
SP2AA_GEOSE
B:
[43-114]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
R
H
I
V
L
N
L
G
Q
L
T
F
M
D
S
S
G
L
G
V
I
L
G
R
Y
K
Q
I
K
N
-
V
G
G
Q
M
V
V
C
A
V
S
P
A
V
K
R
L
F
D
M
S
G
L
F
K
----
I
I
R
V
E
A
D
E
Q
F
A
L
Q
A
L
G
V
A
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
HHSearch
45.63
25%
-25
- C2 -
1SBO
-
Y1442_THEMA
A:
[44-110]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
K
K
I
V
L
D
L
S
S
V
S
Y
M
D
S
A
G
L
G
T
L
V
V
I
L
K
D
A
K
I
-
N
G
K
E
F
I
L
S
S
L
K
E
S
I
S
R
I
L
K
L
T
H
L
D
K
----
I
F
K
I
T
D
T
V
E
E
A
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
HHSearch
45.15
14%
-53
- C2 -
1H4X
1
SP2AA_LYSSH
A:
[42-112]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
T
T
I
I
W
N
F
E
R
L
S
F
M
D
S
S
G
V
G
L
V
L
G
R
M
R
E
L
E
A
-
V
A
G
R
T
I
L
L
N
P
S
P
T
M
R
K
V
F
Q
F
S
G
L
G
P
----
W
M
-
M
D
A
T
E
E
E
A
I
D
R
V
R
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
HHSearch
43.22
10%
-64
- C2 -
3T6O
-
?
A:
[48-120]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
R
K
V
L
I
D
L
E
G
V
E
F
F
G
S
S
F
I
E
L
L
V
R
G
W
K
R
I
K
E
D
Q
Q
G
V
F
A
L
C
S
V
S
P
Y
C
V
E
V
L
Q
V
T
H
I
D
E
----
V
W
P
R
Y
S
T
K
Q
E
A
L
L
A
M
A
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
HHSearch
37.97
19%
23
- C2 -
2KLN
-
?
A:
[48-124]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
E
W
F
V
L
N
A
E
S
N
V
E
V
D
L
T
A
L
D
A
L
D
Q
L
R
T
E
L
L
R
-
R
G
I
V
F
A
M
A
R
V
K
Q
D
L
R
E
S
L
R
A
A
S
L
L
D
-
K
I
G
E
D
H
I
F
M
T
L
P
T
A
V
Q
A
F
R
R
R
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
29
Fugue
31.97
11%
139
- C1 -
4CPC
-
SYCP3_HUMAN
A:
[18-160]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
N
K
A
L
L
A
K
R
K
R
L
E
M
Y
T
K
A
S
L
K
T
--
S
N
Q
K
I
E
H
V
W
K
T
Q
Q
D
Q
R
Q
K
L
N
Q
E
Y
S
Q
Q
F
L
T
L
F
Q
Q
W
D
L
D
M
Q
K
A
E
E
Q
E
E
K
I
L
N
M
F
R
Q
Q
Q
K
I
L
Q
Q
S
R
I
V
Q
S
Q
R
L
K
T
I
-
K
Q
L
Y
E
Q
F
I
K
S
M
E
E
L
E
K
N
H
D
N
L
L
T
G
A
Q
N
E
F
K
K
E
M
A
M
L
Q
K
K
I
M
M
E
T
Q
Q
Q
E
-------
18
HHSearch
31.22
17%
101
- C2 -
3OIZ
-
?
A:
[431-478]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
R
V
V
I
D
V
S
R
A
H
I
W
D
I
S
S
V
Q
A
L
D
M
A
V
L
K
F
R
R
-
E
G
A
E
V
R
I
V
G
M
N
E
A
S
E
T
M
V
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
28
Fugue
30.40
8%
156
- C1 -
3OKQ
-
BUD6_YEAST
A:
[553-677]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
S
N
R
M
Y
M
E
K
S
Q
T
E
L
G
D
L
S
D
T
L
L
S
K
V
D
D
L
Q
D
V
I
E
I
M
R
K
D
V
A
E
RR
S
Q
P
A
K
K
K
L
E
T
V
S
K
D
L
E
N
A
Q
A
D
V
L
K
L
Q
E
F
I
D
T
E
K
P
H
W
K
K
T
W
E
A
E
L
D
K
V
C
E
E
Q
Q
F
L
T
L
Q
E
E
L
I
L
D
L
K
E
D
L
G
K
A
L
E
-
T
F
D
L
I
K
L
C
C
----------------------------------------------
25
Fugue
29.46
12%
128
* C1 *
4PXU
1
KL61_DROME
A:
[8-159]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
S
K
E
I
Q
T
N
L
Q
V
I
E
E
N
N
Q
R
H
K
A
M
L
D
S
M
Q
E
K
F
A
T
I
I
D
S
S
L
Q
S
V
E
E
H
A
K
Q
--
M
H
K
K
L
E
Q
L
G
A
M
S
L
P
D
A
E
E
L
Q
N
L
Q
E
E
L
A
N
E
R
A
L
A
Q
Q
E
D
A
L
L
E
S
M
M
M
Q
M
E
Q
I
K
N
L
R
S
K
N
S
I
S
M
S
V
H
L
N
K
M
E
E
S
R
L
-
T
R
N
H
R
I
D
D
I
K
S
G
I
Q
D
Y
Q
K
L
G
I
E
A
S
Q
S
A
Q
A
E
L
T
-----------------------
27
Fugue
28.97
17%
215
- C1 -
2JEE
-
ZAPB_ECOLI
A:
[3-80]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
S
L
E
V
F
E
K
L
E
A
K
V
Q
Q
A
I
D
T
I
T
L
L
Q
M
E
I
E
E
L
K
E
K
N
N
S
L
S
Q
E
V
Q
N
A
Q
H
Q
R
E
E
L
E
R
E
N
N
-
H
L
K
E
Q
Q
N
G
W
Q
E
R
L
Q
A
L
L
G
R
M
E
E
V
--------------------------------
26
Fugue
28.84
9%
202
- C1 -
3Q8T
-
BECN1_RAT
A:
[172-265]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
S
D
S
E
Q
L
Q
R
E
L
K
E
L
A
L
E
E
E
R
L
I
Q
E
L
E
D
V
E
K
N
R
K
V
V
A
E
N
L
E
K
V
Q
A
E
A
E
R
L
D
Q
E
E
A
Q
Y
Q
R
E
Y
S
E
-
F
K
R
Q
Q
L
E
L
D
D
E
L
K
S
V
E
N
Q
M
R
Y
A
Q
M
Q
L
D
K
L
K
K
K
-----------------------
19
HHSearch
26.61
13%
112
* C2 *
3AGD
-
?
A:
[402-446]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
P
--
I
R
T
V
V
L
N
L
A
R
V
D
R
I
D
D
V
G
R
R
L
I
A
E
G
V
R
R
L
Q
A
-
D
G
V
R
V
E
V
E
D
P
E
R
I
L
P
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
25.92
35%
490
- C3 -
5A1Y
-
?
C:
[770-810]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
A
E
S
L
K
E
T
-
F
D
P
E
K
E
T
I
P
D
I
D
P
N
A
K
L
L
Q
P
P
A
P
I
M
P
L
D
T
N
W
P
L
L
T
V
G
T
S
P
T
Q
I
W
C
N
N
S
Q
L
P
V
D
H
I
L
A
G
S
F
E
T
A
M
R
L
L
H
D
Q
V
G