@TOME V2.2
(Nov 2016)
Ref.
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : S29A1_HUMAN: (2015-12-10 )
MTTSHQPQDRYKAVWLIFFMLGLGTLLPWNFFMTATQYFTNRLDMSQNVSLVTAELSKDAQASAAPAAPLPERNSLSAIFNNVMTLCAMLPLLLFTYLNSFLHQRIPQSVRILGSLVAILLVFLITAILVKVQLDALPFFVITMIKIVLINSFGAILQGSLFGLAGLLPASYTAPIMSGQGLAGFFASVAMICAIASGSELSESAFGYFITACAVIILTIICYLGLPRLEFYRYYQQLKLEGPGEQETKLDLISKGEEPRAGKEESGVSVSNSQPTNESHSIKAILKNISVLAFSVCFIFTITIGMFPAVTVEVKSSIAGSSTWERYFIPVSCFLTFNIFDWLGRSLTAVFMWPGKDSRWLPSLVLARLVFVPLLLLCNIKPRRYLTVVFEHDAWFIFFMAAFAFSNGYLASLCMCFGPKKVKPAEAETAGAIMAFFLCLGLALGAVFSFLFRAIV
Atome Classification :
(20 SA)
----------------.........10.....-----...20......--..30........40..--.-.....50........60........70...-----------------------------.....80---.........90...-...--..100.--------......110-.......120--------------------------....-----------...130..-------.....140...----------....150.....-------------------...160-...-....-.170--.----......-..180.......190.....-..200......--.210---........220.......230....-..-------.240...-....250.......260------.........270..-----.....280..-.....-290.......300...--....310.......320--........330.......340..-----.....350--.......---360.-......370.......380......------------.390.......400-----------.........-410.----......420...-....430-...-......440.-.....--------.450....-------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
----------------MTTSHQ
P
Q
D
R
Y
K
A
V
W
L
-----
I
F
F
M
L
G
L
G
T
LL--
P
W
N
F
F
M
T
A
T
Q
Y
F
T
N
RL--D-MSQN
V
S
L
V
T
A
E
LSKDAQASAAPAAPLPERN-----------------------------
S
L
S
A
I
F
----
N
N
V
M
T
L
C
A
M
L
P
L
L
L
-
F
T
Y
--
L
N
S
F
L
H
--------
Q
R
I
P
Q
S
V
R
I
-
L
G
S
L
V
A
I
L
L
V
--------------------------
F
L
I
T
-----------
A
I
L
V
K
VQL-------DA
L
P
F
F
V
I
T
M
I
----------
K
I
V
L
I
N
-
S
F
G
A
I
-------------------
L
Q
G
S
L
--
F
G
L
-
A
G
LL-PA----S----YTAPIM-SGQ
G
L
A
G
F
F
A
S
V
A
M
I
C
AIAS-GSEL
S
E
S
A
F
G
Y
--
F
I
T
----
A
C
A
V
I
I
L
T
I
I
C
Y
LGL
P
R
L
E
F
Y
R
Y
Y
Q
-
Q
L-------KLEGPGE-QE
T
K
L
D
L
ISKGEEPR--------AGKEESGVSVSNSQ-----PTNE
S
H
S
I
K
A
-
I
L
K
N
I
-
S
V
L
A
F
S
V
C
F
I
F
T
I
TIG--MF
P
A
V
T
V
E
V
KSSIAGS---ST
W
E
R
Y
F
I
P
V
S
C
F
L
T
F
N
I
F
D
W
LG-----R
S
L
T
A
V
F
M
--WPGKDSR---W
L
P
S
-
L
V
L
A
R
L
V
F
V
P
L
L
L
LCNIKP
R
R
Y
L
T
V
------------
V
F
EHD
A
W
F
I
F
F
M
-------------
A
A
F
A
FSN
G
Y
-
L
A
S
L
----
C
M
CFGPKKVKPA-EAE
T
A
---
G
A
I
-
M
A
F
F
L
C
L
G
L
A
-
L
G
A
V
F
--------
S
F
L
F
R
A
IV-------------------------------------------------------
21
Fugue
84.13
16%
-111
- C4 -
4U1C
-
EIF3C_YEAST
C:
[6-549]
-------QEDFFTRLQ
T
I
I
D
S
R
G
K
K
T
V
N
Q
Q
S
L
-----
I
S
T
L
E
E
L
L
T
V
A
EK
P
Y
E
F
I
M
A
Y
L
T
L
I
P
S
R
F
--
D
-
A
S
A
N
L
S
Y
Q
P
I
D
Q
W
K
S
S
F
N
D
I
S
K
L
L
S
I
L
D
Q
T
IDTYQVNEFADPIDFIEDEPKEDSDGVKR
I
L
G
S
I
F
----
S
F
V
E
R
L
D
D
E
F
M
K
S
L
-
L
N
I
DP
H
S
S
D
Y
L
--------
I
R
L
R
D
E
Q
S
I
-
Y
N
L
I
L
R
T
Q
L
Y
--------------------------
F
E
A
T
LKDEHDLERAL
T
R
P
F
V
K
R
L
-------
D
H
I
Y
Y
K
S
E
N
L
I
----------
K
I
M
E
T
A
-
A
W
N
I
I
PAQFKSKFTSKDQLDSADY
V
D
N
L
I
--
D
G
L
-
S
T
I
L
-
S
K
----
Q
----
N
N
I
A
V
Q
-
K
R
A
I
L
Y
N
I
Y
Y
T
A
L
N
K
D
F
Q
T
A
-
K
D
M
L
L
T
S
Q
V
Q
T
--
N
I
N
QFDS
S
L
Q
I
L
F
N
R
V
V
V
Q
L
G
L
S
A
F
K
L
C
L
I
E
E
C
H
Q
-------
I
L
N
D
L
L
S
-
S
S
H
L
R
E
I
L
G
Q
Q
S
L
H
R
--------
I
S
L
N
S
S
----
N
N
A
S
-----
A
D
E
R
A
R
Q
C
L
P
-
Y
H
Q
H
I
-
N
L
D
L
I
D
V
V
F
L
T
C
S
L
L
I
--
E
I
P
R
M
T
A
F
Y
S
----
G
I
---
K
V
K
R
I
P
Y
S
P
K
S
I
R
R
S
L
E
H
Y
D
K
L
S
FQGPP
E
T
L
R
D
Y
V
L
--
F
A
A
K
S
M
Q
KGN
W
R
D
S
-
V
K
Y
L
R
E
I
K
S
W
A
L
L
P
N
M
E
T
V
L
N
S
L
T
E
------------
R
V
Q
V
E
S
L
K
T
Y
F
F
-------------
S
F
K
R
F
Y
S
S
F
S
V
A
K
L
----
A
E
L
F
D
L
P
E
N
K
V
V
-
E
V
L
Q
S
---
V
I
A
-
E
L
E
I
P
A
K
L
N
D
-
E
K
T
I
F
VVEKGDEI
T
K
L
E
E
A
M
V
KL-----------------------------------------------------
25
Fugue
79.51
14%
-142
- C2 -
4OFZ
-
GOB1_BRUMA
A:
[85-513]
----------QT
V
D
D
F
K
N
L
M
Y
K
M
Q
E
T
R
R
A
I
V
F
-----
A
L
L
N
E
K
D
L
T
K
D
--
D
V
E
I
L
K
R
A
Y
E
K
L
T
D
N
F
Q
R
E
-
M
C
T
L
T
T
K
L
S
V
N
I
G
D
E
T
R
G
L
E
K
D
L
K
Y
L
D
A
L
M
-----------------------------
N
I
R
R
E
E
----
P
N
L
L
W
P
I
I
M
S
R
V
D
L
-
F
S
I
--
L
A
N
Y
H
P
--------
K
G
K
E
T
F
L
K
E
-
Y
E
D
T
V
K
F
L
K
T
--------------------------
F
I
S
S
-----------
E
A
I
T
-----------
G
K
K
P
I
F
I
T
D
W
-------------------------------------------
D
G
T
M
--
K
D
Y
-
C
S
Q
Y
-
A
-----
T
----
N
L
Q
P
V
Y
-
S
A
V
G
M
T
R
F
A
A
S
F
T
R
I
S
A
V
L
T
-
A
G
P
L
R
G
P
G
-----
I
L
D
----
L
T
A
M
P
I
D
G
P
V
M
F
S
G
S
W
G
R
E
W
W
L
S
G
K
-
R
V
-------
V
H
Q
D
G
I
T
-
D
E
G
F
N
A
L
Q
R
L
D
D
E
M
K
--------
D
L
L
H
T
S
P
F
A
L
V
G
S
------------
G
V
Q
R
-
K
V
D
R
L
-
T
L
G
V
Q
T
V
C
H
--
H
V
T
S
E
--
L
S
N
R
Y
Q
M
A
V
K
E
R
M
H
N
S
-------------------
Q
I
L
V
F
D
P
-----
S
T
E
L
E
V
E
V
--
V
A
H
N
S
G
I
I--
W
N
K
G
-
N
G
V
E
R
L
I
K
S
---
L
G
D
S
L
Q
S
P
G
K
I
L
I
------------
C
G
D
T
L
S
D
I
P
M
V
R
-------------
Q
A
V
K
Q
N
P
D
G
-
V
--
L
----
A
I
F
V
G
A
K
M
S
L
R
E
-
E
V
K
Q
V
I
GD
E
S
R
-
C
C
F
V
S
C
P
D
V
I
-
H
A
A
M
S
--------
Q
I
L
N
E
H
C
I
G------------------------------------------------------
19
Fugue
74.95
17%
-106
- C4 -
4KQA
2
FA20C_CAEEL
A:
[3-428]
-------------------
P
H
Q
P
--------------
I
P
P
S
L
G
E
K
D
L
S
D-
P
F
N
F
L
F
S
S
N
K
I
T
L
R
K
L
--
Y
D
L
T
K
N
V
D
F
D
Q
L
R
Q
N
E
C
K
K
N
I
T
L
S
K
F
W
E
P
E
D
D
-----------------------------
N
W
E
R
F
Y
----
S
N
I
G
S
-
C
S
V
Y
S
D
D
Q
M
I
D
N
--
L
L
H
D
L
N
--------
T
S
P
I
K
H
V
H
I
M
D
G
T
Q
V
K
F
V
F
T
--------------------------
F
K
------------------------------------
N
D
K
----------
Q
A
V
F
K
P
M
R
F
G
R
D
-------------------
Y
E
S
D
P
NH
F
Y
F
-
S
D
F
E
-
R
H
----
H
----
A
E
I
A
T
F
-
H
L
D
R
V
L
G
F
R
R
A
I
P
T
V
G
R
V
L
N
M
T
T
E
L
F
E
K
A
E
K
K
--
L
K
K
----
T
F
F
F
S
P
A
K
N
F
C
F
V
S
--
R
C
D
Y
Y
C
D
-
T
-
T
H
-------
A
I
C
G
L
P
D
M
K
E
G
S
V
Q
V
F
L
----
P
D
--------
E
S
A
V
P
R
K
H
N
R
S
P
Y
R
-----
R
T
Y
S
K
K
N
Q
V
A
-
E
W
Q
S
S
M
N
Y
C
T
D
K
V
K
T
K
R
Q
Y
A
H
G
R
R
L
L
D
L
V
D
I
H
I
L
D
Y
L
I
G
N
QDR
H
H
F
E
S
F
N
V
F
-
N
D
L
P
S
Y
A
I
H
L
D
H
G
-----
R
A
----
F
G
--
R
S
D
F
D
D
D
---
D
----------
I
I
L
P
L
R
Q
C
C
I
L
R
P
S
T
F
Q
T
L
M
-----------
N
F
--------
Y
S
-------------
T
P
K
S
L
T
K
A
L
-
H
E
S
L
S
K
DP
A
H
P
I
L
A
Y
K
H
Y
P
A
M
E
-
R
R
L
---
A
K
I
M
S
H
I
L
E
C
F
E
S
R
G
V
A
E
V
L
--------
V
A
E
Y
N
N
P
D
-------------------------------------------------------
24
Fugue
59.69
13%
-126
- C2 -
1OLZ
-
SEM4D_HUMAN
A:
[3-627]
FAPIPR
I
T
W
E
HRE
V
H
L
V
Q
F
H
E
P
D
I
Y
N
Y
S
A
L
L
L
S
EDKD
T
L
Y
I
G
A
R
E
A
V
F
--
A
V
N
A
L
N
I
S
E
K
Q
H
E
V
Y
W
--
K
-
V
S
E
D
K
K
A
K
C
A
E
K
G
K
S
K
Q
T
E
C
L
N
Y
I
R
V
L
Q
P
L
-----------------------------
S
A
T
S
L
Y
V
C
G
T
N
A
F
Q
P
A
C
D
H
L
N
L
T
S
-
F
K
F
--
L
G
K
N
E
D
GKGRCPFD
P
A
H
S
Y
T
S
V
M
-
V
D
G
E
L
Y
S
G
T
S
YNFLGSE
P
I
I
S
R
N
S
S
H
S
P
L
R
T
E
YAIP
W
L
N
E
-----------
P
S
F
V
F
A
D
V
IRKSPG
E
D
D
R
V
Y
F
F
F
T
E
V
SVE
Y
E
F
V
F
R
V
L
I
P
R
I
A
-
R
V
C
K
G
-------------------
D
Q
G
G
L
--
R
T
L
-
Q
K
K
W
-
T
S
----
F
----
L
K
A
R
L
I
C
S
R
P
D
S
G
L
V
F
N
V
L
R
D
V
F
V
L
R
S
-
P
G
L
K
V
P
V
F
Y
A
L
--
F
T
P
----
Q
L
N
N
V
G
L
S
A
V
C
A
Y
N
L
S
T
A
E
E
V
F
S
H
G
-
K
Y
-------
M
Q
S
T
T
V
E
-
Q
S
H
T
K
W
V
R
Y
N
G
P
V
P
K
PRPGACID
S
E
A
R
A
A
N
Y
T
S
S
L
N
L
-----
P
D
K
T
L
Q
F
V
K
D
H
P
L
M
D
D
-
S
V
T
P
I
D
N
R
P
R
L
I
K
K
D
V
--
N
Y
T
Q
I
V
V
D
R
T
Q
A
L
D
G
T
----
V
Y
D
V
M
F
V
S
T
D
R
G
A
L
H
K
A
I
S
L
E
H
-----
A
V
H
I
I
E
E
T
--
Q
L
F
Q
D
F
E
---
P
V
Q
T
-
L
L
L
S
S
K
K
G
N
R
F
V
Y
A
G
S
N
S
G
V
V
Q
A
P
L
AFCGKHGT
C
E
D
C
V
L
A
R
D
P
Y
C
A
W
S
P
PTATCVALHQTES
P
S
R
G
L
I
Q
E
M
-
S
G
D
A
----
S
V
C
P
D
K
S
K
G
S
Y
R
-
Q
H
F
F
K
---
H
G
G
-
T
A
E
L
K
C
S
Q
K
S
-
N
L
A
R
V
--------
F
W
K
F
Q
N
G
V
LKAESPK
Y
G
L
MGRK
N
L
L
I
F
NLSEGD
S
G
V
Y
Q
C
L
S
E
E
R
V
KN
K
T
V
F
Q
VV
A
K
H
V
L
E
V
K
V
13
HHSearch
48.77
9%
-158
- C3 -
3WDO
-
?
A:
[12-154]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
-
W
G
L
G
T
V
F
S
L
R
M
L
G
M
F
M
--
V
L
P
V
L
T
T
Y
G
M
A
L
Q
G
------
A
-
S
E
A
L
I
G
-
I
A
I
G
I
Y
G
L
T
Q
A
V
F
-----
Q
I
P
F
G
L
L
S
D
R
I
G
R
K
--
P
---
L
I
V
G
-
G
L
A
V
F
A
A
G
---
S
V
I
A
A
L
---------------------
S
D
S
I
W
G
I
I
L
G
R
-------------
A
L
Q
G
S
G
A
---
I
A
A
A
----
V
M
A
L
L
S
D
L
T
R
E
Q
-
N
R
T
K
A
---
M
A
F
-
I
G
V
S
F
G
I
T
F
A
-
I
A
M
V
L
--------
G
P
I
I
T
H
K
L
-------------------------------------------------------
8
HHSearch
42.40
10%
-166
- C3 -
3O7Q
1
FUCP_ECOLI
A:
[64-170]
--------------------------------------------------------------------------------------------------------------------------------------------
G
L
I
Q
S
A
F
Y
F
G
Y
F
I
-
I
P
I
--
P
A
G
I
L
M
--------
K
K
L
S
Y
K
A
G
I
-
I
T
G
L
F
L
Y
A
L
G
--------------------------
A
A
L
F
-----------
W
P
A
A
------------
E
I
M
N
Y
T
L
F
L
V
----------
G
L
F
I
I
A
-
A
G
L
G
C
-------------------
L
E
T
A
A
--
N
P
F
-
V
T
V
L
G
P
E
----
S
S
G
H
F
R
L
N
L
A
Q
-
T
F
N
S
F
G
A
I
I
A
V
V
F
G
Q
S
L
I
L
S
-
N
V
P
H
Q
S
Q
D
V
L
D
--
K
M
S
----
P
E
Q
L
S
A
Y
K
H
S
L
V
L
S
V
Q
T
P
Y
M
I
I
V
A
I
-
V
L
-------
L
V
A
L
L
I
M
-
L
T
K
F
P
A
L
Q
S
D
N
H
S
D
A
--------
K
Q
G
S
F
S
A
S
L
S
R
L
A
R
-----
I
R
H
W
R
W
A
V
L
A
-
Q
F
C
Y
V
-
G
A
Q
T
A
C
W
S
Y
L
I
R
Y
A
V
E
--
E
I
P
G
M
T
A
G
F
A
A
N
Y
L
T
G
---
T
M
V
C
F
F
I
G
R
F
T
G
T
W
L
I
S
R
F
A
P
H
K
-----
V
L
A
A
Y
A
L
I
--
A
M
A
L
C
L
I
---
S
A
F
A
-
G
G
H
V
G
L
I
A
L
T
L
C
S
A
F
M
S
I
Q
Y
P
T
I
F
S
------------
L
G
I
K
N
L
G
Q
D
T
K
Y
-------------
G
S
S
F
I
V
M
T
I
-
I
G
G
G
----
I
V
T
P
V
M
G
F
V
S
D
A
-
A
G
N
I
P
---
T
A
E
-
L
I
P
A
L
C
F
A
V
I
-
F
I
F
A
R
--------
F
R
S
Q
T
----------------------------------------------------------
15
HHSearch
40.96
12%
-120
- C3 -
3O7Q
1
FUCP_ECOLI
A:
[65-173]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
I
Q
S
A
F
Y
F
G
Y
F
I
I
-----
P
I
P
A
G
I
L
M
--
K
-
K
L
S
Y
K
---
A
G
I
I
-
T
G
L
F
--
L
Y
A
L
G
A
A
L
F
W
P
A
A
------------------
E
I
M
N
Y
T
L
F
L
V
G
L
-------------
F
I
I
A
A
G
L
G
C
-
L
E
T
A
----
A
N
P
F
V
T
V
L
G
P
E
S
-
S
G
H
F
R
---
L
N
L
-
A
Q
T
F
N
S
F
G
A
I
-
I
A
V
V
F
--------
G
Q
S
L
I
L
S
N
-------------------------------------------------------
12
HHSearch
38.77
7%
-109
- C3 -
1PW4
-
GLPT_ECOLI
A:
[67-175]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
A
L
S
G
I
S
I
A
Y
G
F
S
-----
K
F
I
M
G
S
V
S
--
D
R
-
S
N
P
R
---
V
F
L
P
A
G
L
I
L
A
A
A
V
M
L
---
F
M
G
F
V
P
W
-----------------
A
T
S
S
I
A
V
M
F
V
L
L
-------------
F
L
C
G
W
F
Q
G
M
-
G
W
P
P
----
C
G
R
T
M
V
H
W
W
S
Q
K
-
E
R
G
G
I
---
V
S
V
-
W
N
C
A
H
N
V
G
G
G
-
I
P
P
L
L
--------
F
L
L
G
M
A
W
F
-------------------------------------------------------
4
PsiBlast_PDB
36.17
37%
-60
- C3 -
3WFD
5
NORB_PSEAE
B:
[321-372]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
A
G
V
W
G
F
M
H
T
L
A
P
V
N
Y
Y
T
H
-
G
T
Q
L
T
-
A
A
H
G
H
MA
F
Y
G
----
A
Y
A
M
I
V
M
T
I
I
S
Y
-
A
M
P
R
L
R
G
I
G
E
A
M
-
D
N
-------
R
S
Q
V
L
E
M
-
W
G
F
W
L
M
T
V
A
M
V
F
I
T
L
--------
F
L
S
A
A
G
V
L
Q
V
W
L
Q
R
-----
M
P
A
D
G
A
A
M
T
F
-
M
A
T
Q
D
-
Q
L
A
I
F
Y
W
L
R
E
G
A
G
V
V
F
--
L
I
G
L
V
A
Y
L
L
S
F
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
35.23
37%
-60
- C3 -
3O0R
2
NORB_PSEAE
B:
[321-372]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
A
G
V
W
G
F
M
H
T
L
A
P
V
N
Y
Y
T
H
-
G
T
Q
L
T
-
A
A
H
G
H
MA
F
Y
G
----
A
Y
A
M
I
V
M
T
I
I
S
Y
-
A
M
P
R
L
R
G
I
G
E
A
M
-
D
N
-------
R
S
Q
V
L
E
M
-
W
G
F
W
L
M
T
V
A
M
V
F
I
T
L
--------
F
L
S
A
A
G
V
L
Q
V
W
L
Q
R
-----
M
P
A
D
G
A
A
M
T
F
-
M
A
T
Q
D
-
Q
L
A
I
F
Y
W
L
R
E
G
A
G
V
V
F
--
L
I
G
L
V
A
Y
L
L
S
F
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
HHSearch
34.36
8%
-123
- C3 -
1PW4
-
GLPT_ECOLI
A:
[66-174]
--------------------------------------------------------------------------------------------------------------------------------------------
G
F
A
L
S
G
I
S
I
A
Y
G
F
-
S
K
F
--
I
M
G
S
V
S
--------
D
R
S
N
P
R
V
F
L
-
P
A
G
L
I
L
A
A
A
V
--------------------------
M
L
F
M
-----------
G
F
V
P
W
--
A
---------
T
S
S
I
A
V
M
F
V
----------
L
L
F
L
C
G
-
W
F
Q
G
M
-------------------
G
W
P
P
C
--
G
R
T
M
V
H
W
W
-
S
Q
K
E
R
G
G
----
I
V
S
V
W
N
-
C
A
H
N
V
G
G
G
I
P
P
L
L
F
L
L
G
M
A
W
-
F
N
D
W
H
A
A
L
Y
M
P
--
A
F
C
----
A
I
L
V
A
L
F
A
F
A
M
M
R
D
T
P
Q
S
C
G
L
P
P
I
E
-
E
Y
-------
K
N
D
T
A
K
Q
-
I
F
M
Q
Y
V
L
P
N
K
L
L
W
Y
I
--------
A
I
A
N
V
F
V
Y
L
L
R
Y
G
I
-----
L
D
W
S
P
T
Y
L
K
E
-
V
K
H
F
A
-
L
D
K
S
S
W
A
Y
F
L
Y
E
Y
A
G
I
--
P
G
T
L
L
C
G
W
M
S
D
K
V
F
R
G
---
N
R
G
A
T
G
V
F
F
M
T
L
V
T
I
A
T
I
V
Y
W
M
N
-----
P
A
G
N
P
T
V
D
--
M
I
C
M
I
V
I
---
G
F
L
I
-
Y
G
P
V
M
L
I
G
L
H
A
L
E
L
A
P
K
K
A
A
G
T
A
A
G
------------
F
T
G
L
F
G
Y
L
G
G
S
V
-------------
A
A
S
A
I
V
G
Y
T
-
V
D
F
F
----
G
W
D
G
G
F
M
V
M
I
G
G
-
S
I
L
A
V
---
I
L
L
-
I
V
V
M
I
G
E
K
R
R
-
H
E
Q
L
L
--------
Q
E
L
V
P
----------------------------------------------------------
2
PsiBlast_PDB
34.01
37%
-59
- C3 -
3WFB
2
NORB_PSEAE
B:
[321-372]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
A
G
V
W
G
F
M
H
T
L
A
P
V
N
Y
Y
T
H
-
G
T
Q
L
T
-
A
A
H
G
H
MA
F
Y
G
----
A
Y
A
M
I
V
M
T
I
I
S
Y
-
A
M
P
R
L
R
G
I
G
E
A
M
-
D
N
-------
R
S
Q
V
L
E
M
-
W
G
F
W
L
M
T
V
A
M
V
F
I
T
L
--------
F
L
S
A
A
G
V
L
Q
V
W
L
Q
R
-----
M
P
A
D
G
A
A
M
T
F
-
M
A
T
Q
D
-
Q
L
A
I
F
Y
W
L
R
E
G
A
G
V
V
F
--
L
I
G
L
V
A
Y
L
L
S
F
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
30.83
37%
-57
- C3 -
3WFC
5
NORB_PSEAE
B:
[321-372]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
A
G
V
W
G
F
M
H
T
L
A
P
V
N
Y
Y
T
H
-
G
T
Q
L
T
-
A
A
H
G
H
MA
F
Y
G
----
A
Y
A
M
I
V
M
T
I
I
S
Y
-
A
M
P
R
L
R
G
I
G
E
A
M
-
D
N
-------
R
S
Q
V
L
E
M
-
W
G
F
W
L
M
T
V
A
M
V
F
I
T
L
--------
F
L
S
A
A
G
V
L
Q
V
W
L
Q
R
-----
M
P
A
D
G
A
A
M
T
F
-
M
A
T
Q
D
-
Q
L
A
I
F
Y
W
L
R
E
G
A
G
V
V
F
--
L
I
G
L
V
A
Y
L
L
S
F
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
HHSearch
30.82
8%
-91
- C3 -
2GFP
-
EMRD_ECOLI
A:
[47-153]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
V
M
G
A
Y
L
L
T
Y
G
V
S
-----
Q
L
F
Y
G
P
I
S
--
D
R
-
V
G
R
R
---
P
V
I
L
V
G
M
S
I
F
M
L
A
---
T
L
V
A
V
T
---------------------
T
S
S
L
T
V
L
I
A
A
S
-------------
A
M
Q
G
M
G
T
G
V
-
G
G
V
M
----
A
R
T
L
P
R
D
L
Y
E
R
T
-
Q
L
R
H
A
---
N
S
L
-
L
N
M
G
I
L
V
S
P
L
-
L
A
P
L
I
--------
G
G
L
L
D
T
M
W
-------------------------------------------------------
5
PsiBlast_PDB
29.81
37%
-61
- C3 -
3WFE
4
NORB_PSEAE
B:
[321-372]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
A
G
V
W
G
F
M
H
T
L
A
P
V
N
Y
Y
T
H
-
G
T
Q
L
T
-
A
A
H
G
H
MA
F
Y
G
----
A
Y
A
M
I
V
M
T
I
I
S
Y
-
A
M
P
R
L
R
G
I
G
E
A
M
-
D
N
-------
R
S
Q
V
L
E
M
-
W
G
F
W
L
M
T
V
A
M
V
F
I
T
L
--------
F
L
S
A
A
G
V
L
Q
V
W
L
Q
R
-----
M
P
A
D
G
A
A
M
T
F
-
M
A
T
Q
D
-
Q
L
A
I
F
Y
W
L
R
E
G
A
G
V
V
F
--
L
I
G
L
V
A
Y
L
L
S
F
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26
Fugue
29.27
15%
123
* C2 *
1RP3
-
?
B:
[2-88]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
N
R
I
E
L
S
R
L
I
G
-
L
L
L
E
TSGTN
K
I
E
D
K
V
T
-
L
S
K
I
A
Q
E
L
S
K
N
D
V
E
E
--------
K
D
L
E
K
K
V
K
E
L
K
E
K
I
E
K
GE
Y
E
V
S
D
E
K
V
V
K
G
-
L
I
E
F
F
-
T
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
HHSearch
26.99
16%
-18
- C3 -
3WDO
-
?
A:
[301-356]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
W
Q
L
V
V
G
V
-------------
Q
L
F
F
V
A
F
N
L
-
M
E
A
L
----
L
P
S
L
I
S
K
E
S
P
A
G
-
Y
K
G
T
A
---
M
G
V
-
Y
S
T
S
Q
F
L
G
V
A
-
I
G
G
S
L
--------
G
G
W
I
D
G
M
F
-------------------------------------------------------
20
Fugue
26.86
21%
264
* C3 *
2FYZ
-
?
B:
[448-479]
--------------------------------------------------------------------
D
-
I
S
T
E
L
S
K
V
N
A
S
L
Q
N
T
V
K
Y
I
K
E
S
N
H
Q
L
Q
S
V
I
-----------------------------
V
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
Fugue
26.32
21%
287
* C4 *
1HJ0
-
TYB10_BOVIN
A:
[1-41]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
D
K
P
D
L
G
E
I
N
S
F
D
K
--------
A
K
L
K
K
T
E
T
Q
E
K
N
T
L
-----
P
T
K
E
T
I
E
Q
E
K
-
Q
A
K
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17
Fugue
25.48
28%
218
- C3 -
1SVF
-
?
B:
[1-38]
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Q
I
L
S
I
D
P
L
--
D
-
I
S
Q
N
L
A
A
V
N
K
S
L
S
D
A
L
Q
H
L
A
Q
S
D
T
Y
L
S
A
I
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