@TOME V2.2
(Nov 2016)
Ref.
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
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Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : S35E3_HUMAN: (2015-12-10 )
MALLVDRVRGHWRIAAGLLFNLLVSICIVFLNKWIYVYHGFPNMSLTLVHFVVTWLGLYICQKLDIFAPKSLPPSRLLLLALSFCGFVVFTNLSLQNNTIGTYQLAKAMTTPVIIAIQTFCYQKTFSTRIQLTLIPITLGVILNSYYDVKFNFLGMVFAALGVLVTSLYQVWVGAKQHELQVNSMQLLYYQAPMSSAMLLVAVPFFEPVFGEGGIFGPWSVSALLMVLLSGVIAFMVNLSIYWIIGNTSPVTYNMFGHFKFCITLFGGYVLFKDPLSINQALGILCTLFGILAYTHFKLSEQEGSRSKLAQRP
Atome Classification :
(15 SA)
---------------------------------------------.........10-------------------------........--------.20........30........40.......-----.50......------..60......----..70..---..--....80..--....---..90.-----------.......100.-.-.....110-----....----.----------------....120----.-.......130-.......140----.......150...-------....160-----.......170.-......180...--....190.----------.--------..--...200-.....----..210...-....220.......230...---.....-240....--...250--....-----...-------------..260.......270.---..---------------.....280.---------.....--.290.....-------...300..------.....310.---------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
---------------------------------------------MALLVDRVRG--------------------------HWRIAAGL--------LFNLLVSICIVFLNKWIYVYHGFPNMSLTL-----VHFVVTWLG------LYICQKLDIF----APKSLP---PS--RLLLLALS--FCGF---VVFTN-----------LSLQNNTIGTY-Q-LAKAMT-------TPVI----I----------------AIQTFC-----Y-QKTFSTRIQL-TLIPITLGVI----LNSYYDVKFNFLG-------MVFAALG-----VLVTSLYQVWV-GAKQHELQVNSM--QLLYYQAP----------M--------SS--AMLLVA-VPFFE----PVFGEGGI-FGPWSVSALLMVLLSG-VIA---FMVNL-SIYWIIG--NTSP----VTYN-----MFG-------------HFKFCITLFGGYVL-F---KD---------------PLSINQALG---------ILCTL--FGI-LAYTH-------FKLSEQEG------SRSKLAQRP---------------------------------------------------
13
Fugue
87.05
18%
-157
- C3 -
4MUO
-
YBIB_ECOLI
A:
[1-320]
----------------------------------------MD
Y
R
K
I
I
K
E
I
G
R
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K
N
--------------------------
H
A
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---
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K
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---
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GK
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--------
A
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A
A
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---------------------------------------------------
19
Fugue
86.40
18%
-112
- C5 -
4MFL
4
?
A:
[23-345]
---------------------------------------------
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DHRAKPRGGPP
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---
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--
L
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-
A
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H
------
M
R
T
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K
L
P
---------------------------------------------------
14
Fugue
86.02
17%
-131
- C4 -
1E6Y
3
MCRB_METBF
B:
[185-432]
-----------------------------------------------
G
F
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N
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--------------------------
A
N
H
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------------------------------------------
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---
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NAN
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-----------
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-------------------
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A
A
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--
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G
-
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----------------
G
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A
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S
H
-
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P
-
G
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---
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--
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G
----------------
F
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-
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DAG
T
Q
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M
F
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T
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G
---------
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-
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V
-----------------------------------------------------------
15
Fugue
79.17
18%
-135
- C4 -
1MRO
3
MCRB_METTM
B:
[188-442]
-----------------------------------------------
G
Y
A
L
R
N
I
M
--------------------------
V
N
H
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------------------------------------------
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-
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F
F
S
----------------
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S
I
Y
G
--
G
G
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P
----
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F
N
GNHIV
T
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-------------
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K
G
F
A
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C
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A
A
A
M
A
-
L
DAG
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E
A
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---------
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A
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I
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N
E
I
---------------------------------------------------
10
Fugue
76.05
13%
-146
* C4 *
1QRR
2
SQD1_ARATH
A:
[2-391]
-------------------K
R
V
M
V
I
GGDG
Y
C
G
W
A
T
A
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K
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NYE
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C
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N
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R
--------------------------
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L
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E
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A
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G
LEPHYLS
D
S
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--
L
N
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-
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MPSVSW
K
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S
---------------------------------------------------
11
Fugue
66.13
14%
-142
* C5 *
4OL8
2
YG31B_YEAST
A:
[24-461]
---------------------------------------------
P
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TVMPFGLVN
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Y-----------------------------------------
17
Fugue
57.51
14%
-112
- C2 -
4L6Y
-
PRC1_HUMAN
A:
[6-454]
R
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N
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GIP
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L
R
E
T
K
A
-----
S
-
R
R
E
E
F
V
S
I
K
R
-
Q
I
I
L
C
M
E
E
L
D
----
H
T
P
D
T
S
F
E
R
D
V
V
C
EDEDAFC
L
S
L
E
N
I
A
-----
T
L
Q
K
L
L
R
Q
L
E
M
-
Q
K
S
Q
N
E
A
V
C
E
G
L
--
R
T
Q
I
R
E
L
W
----------
D
R
L
QIP
E
E
E
R
E
--
A
V
A
T
I
M
-
S
G
S
K
A
----
K
V
R
K
A
L
Q
L
-
E
V
D
R
L
E
E
L
K
M
Q
N
M
K
K
V
-
I
E
A
---
I
R
V
E
L
-
V
Q
Y
W
D
Q
C
--
F
Y
S
Q
----
E
Q
R
Q
-----
A
F
A
PFCAEYT
E
S
L
L
Q
L
H
D
A
E
I
V
R
L
K
N
Y
Y
E
V
-
H
---
K
E
---------------
L
F
E
G
V
Q
K
W
E
---------
E
T
W
R
L
--
F
L
E
-
F
E
R
K
A
S
DPNRRG
G
N
L
L
K
E
E
K
------
Q
R
A
K
L
Q
K
M
L
P
K
L
E
E
E
L
K
A
R
I
E
L
W
E
Q
EHSK
A
F
M
V
NGQKFM
E
Y
V
A
E
Q
W
E
M
H
R
L
E
K
E
R
A
K
Q
E
R
2
HHSearch
35.65
9%
-173
- C- -
3B5D
1
EMRE_ECOLI
A:
[30-105]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
W
P
S
V
G
T
I
-
I
C
Y
---
C
A
S
F
W
-
L
L
A
Q
T
L
A
--
Y
I
P
T
----
G
I
A
Y
A
----
I
W
S
-------------
G
V
G
I
V
L
I
S
L
L
S
W
G
F
-
F
---
G
Q
---------------
R
L
D
L
P
A
I
I
G
---------
M
M
L
I
C
--
A
G
V
-
L
I
I
N
L
-------
L
S
------------------------------------------------------------------------
3
HHSearch
28.03
9%
-74
- C- -
3B5D
1
EMRE_ECOLI
A:
[30-105]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
W
--
P
S
V
G
T
I
I
C
--
Y
C
A
S
---
F
W
L
L
A
-----------
Q
T
L
A
Y
I
P
T
G
I
A
-
Y
A
I
W
S
G
V
G
-------
I
V
L
I
----
S
----------------
L
L
S
W
G
F
-----
F
-
G
Q
R
L
D
L
P
A
I
I
-
G
M
M
L
I
C
A
G
V
L
----
I
I
N
L
L
S
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
HHSearch
22.59
21%
166
- C6 -
2JP3
-
FXYD4_RAT
A:
[23-46]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
F
G
---------
G
L
L
C
I
--
A
G
I
-
A
L
A
L
S
-------
G
K
C
K
C
R
R
N
------
H
T
P
S
S
L
P
E
K
---------------------------------------------------
9
HHSearch
20.04
14%
131
* C6 *
2JO1
-
PLM_HUMAN
A:
[22-42]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
I
A
---------
G
I
L
F
I
--
L
G
I
-
L
I
V
L
S
-------
R
R
C
R
C
K
F
N
------
Q
Q
Q
R
T
G
E
P
D
---------------------------------------------------
8
HHSearch
17.05
14%
238
- C6 -
2ZXE
-
?
G:
[25-42]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
V
A
---------
A
V
L
C
V
--
I
G
I
-
I
I
L
L
A
-------
G
K
------------------------------------------------------------------------
12
Fugue
16.18
43%
144
- C6 -
1VF5
-
PETG_MASLA
G:
[9-31]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
V
L
G
-------
L
V
F
A
T
L
G
-----
G
L
F
Y
A
A
Y
Q
Q
Y
K
-
R
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
Fugue
14.20
28%
487
- C1 -
1M5N
-
Q:
[67-94]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
-----------
L
T
Q
E
T
N
K
V
E
T
Y
-
K
-
E
Q
P
L
K
T
PGKKKKG
K
P
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
HHSearch
13.35
14%
257
- C6 -
3WGU
2
?
G:
[32-48]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
F
A
---------
A
L
A
F
I
--
V
G
L
-
I
I
I
L
S
-------
K
-------------------------------------------------------------------------