@TOME V2.2
(Nov 2016)
Ref.
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : S35G2_HUMAN: (2015-12-10 )
MDTSPSRKYPVKKRVKIHPNTVMVKYTSHYPQPGDDGYEEINEGYGNFMEENPKKGLLSEMKKKGRAFFGTMDTLPPPTEDPMINEIGQFQSFAEKNIFQSRKMWIVLFGSALAHGCVALITRLVSDRSKVPSLELIFIRSVFQVLSVLVVCYYQEAPFGPSGYRLRLFFYGVCNVISITCAYTSFSIVPPSNGTTMWRATTTVFSAILAFLLVDEKMAYVDMATVVCSILGVCLVMIPNIVDEDNSLLNAWKEAFGYTMTVMAGLTTALSMIVYRSIKEKISMWTALFTFGWTGTIWGISTMFILQEPIIPLDGETWSYLIAICVCSTAAFLGVYYALDKFHPALVSTVQHLEIVVAMVLQLLVLHIFPSIYDVFGGVIIMISVFVLAGYKLYWRNLRKQDYQEILDSPIK
Atome Classification :
(19 SA)
.........----------------------10.......--------------.20........30........40........50....--....60....---....--70........80.-----.......90....--....100.......110------........120..-..-...130.......140-------......-------..150.....---..160....---...170.......180..--------------.....190----.....-....-----------200.......210.......220....----....230.......240.......250.......260......--------..270...------------------------....280.......290-------...---....300.---...--....310.......320.......330.------......340.....-----.-.350.....--..360.......-----370----........380.--------------......390----..------......400-----........410------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MDTSPSRKY----------------------PVK
K
R
V
K
IH--------------P
N
T
V
M
V
K
YTSHYPQPGD
D
G
Y
E
E
I
N
E
G
Y
G
N
F
M
EENPKK--
G
L
L
S
E
M
K
K
KG---R
A
F
F--GTMDTLPPPTED
P
-----
M
I
N
E
I
G
Q
F
Q
S
F
A
E
--
K
N
I
F
QSR
K
M
W
I
V
L
F
G
S
-------
A
L
A
H
G
C
V
A
L
I
T
R
L
-VS-DRSKVPS
L
E
L
I
F
I
R
S
--------
V
F
Q
V
L
S
-------
V
L
V
V
C
Y
YQEA---PFGPSG
Y
R
L
---
R
L
F
F
YGV
C
N
V
I
S
I
T
C
A
Y
T
--------------
S
F
S
I
VP------PSNG
T
-
T
M
W
R
-----------
A
T
T
T
V
F
S
A
I
L
A
F
L
L
VDE
K
M
A
Y
-
V
D
M
A
T
----
V
V
C
S
I
L
G
V
C
L
V
MIPNIVDED
N
S
L
L
N
A
W
K
E
AFG
Y
T
M
-
T
V
M
A
G
L
T
--------
T
A
L
S
M
I
V
Y
------------------------
R
S
I
K
E
K
I
S
M
W
T
A
L
F
TFG-------WT
G
---
T
IWG
I
S
-
T
---
M
F
I
--LQEPIIPLDGE
T
W
S
Y
L
I
A
I
C
V
C
S
T
A
A
F
L
------
G
V
Y
Y
A
L
D
KF
H
P
A
L
V
-----
S
-
T
V
Q
H
L
E
I
V
V
--
A
M
V
L
Q
L
L
V
L
H
I
F
-----
P
S
-----
I
Y
D
V
F
G
G
V
I
I
M
I
--------------
S
V
F
V
L
AG
Y
-----
K
L
------
Y
W
R
NL
R
K
Q
------
D
Y
Q
E
I
LDSPIK------------------------------------------------------------------------
16
Fugue
85.21
10%
-109
- C4 -
1OJ7
2
YQHD_ECOLI
A:
[19-408]
K
A
G
L
N
N
F
N
L
----------------------
H
T
P
T
R
I
L
F
G
--------------
K
G
----
A
I
A
G
L
R
E
Q
I
P
H
D
A
R
V
L
I
T
Y
G
G
G
S
V
K
K
T
G
V
L
D
--
Q
V
L
D
A
L
K
G
M
D
---
V
L
E
F
--
G
G
I
E
--
P
N
P
A
Y
E
T
-----
L
M
N
A
V
K
L
V
R
E
Q
K
V
--
T
--------
F
L
L
A
V
G
G
-------
G
S
V
L
D
G
T
K
F
I
A
A
A
-
A
N
-
Y
P
E
N
I
D
P
W
H
I
L
Q
T
G
G
--------
K
E
I
K
S
A
-------
I
P
M
G
C
V
L
T
L
P
---
A
T
G
-----------------------
S
E
S
N
--------------
A
G
A
V
I
S
------
R
K
T
T
G
-
D
K
Q
A
-----------
F
H
S
A
H
V
--
Q
P
V
F
A
V
L
D
P
V
Y
T
Y
T
L
P
P
R
Q
----
V
A
N
G
V
V
D
A
F
V
H
T
V
E
Q
Y
V
T
K
P
V
D
A
K
I
H
D
R
F
A
E
G
I
L
L
-
T
L
I
E
D
G
P
--------
K
A
L
K
E
P
E
N
------------------------
Y
D
V
R
A
N
V
M
W
A
A
T
Q
A
L
N
G
-------
L
I
G
---
A
G
V
P
Q
D
W
A
---
T
H
M
--
L
G
H
E
L
T
A
M
H
G
L
D
H
A
Q
T
L
A
I
V
L
P
A
L
W
N
E
K
RD----
T
K
R
A
K
L
L
Q
Y
A
E
R
V
W
NITEG
S
-
D
D
E
R
I
D
A
A
I
--
A
A
T
R
N
F
F
E
Q
L
G
V
-----
P
T
-----
H
L
S
D
Y
G
L
D
G
S
S
I
--------------
P
A
L
L
K
K
L
E
-----
E
H
GMTQLG
E
N
H
D
I
T
L
D
------
V
S
R
R
I
Y
E
A
A
R
-------------------------------------------------------------------------
19
Fugue
82.68
19%
-123
- C2 -
4Y97
-
DPOA2_HUMAN
A:
[157-598]
----
P
S
Q
K
Y
N
S
R-------------------
S
N
R
G
E
V
V
T
S
FGLAQGVSWSGRGG
A
G
N
I
S
L
K
V
L
G
C
-
P
E
A
L
T
G
S
Y
K
S
M
F
Q
K
L
P
D
I
R
E
V
L
T
C
K
I
E
E
L
G
S
E
L
K
E
H
Y
---
K
--
I
--
E
A
F
T
P
L
L
A
P
A
Q
E
P
------
V
T
L
L
G
Q
I
G
C
D
S
N
--
G
K
L
N
N
K
S
---
V
I
L
E
G
D
-------
R
E
H
S
S
G
A
Q
I
P
V
D
L
-
S
E
L
K
E
Y
S
L
F
P
G
Q
V
V
I
M
E
G
--------
I
N
T
T
G
R
-------
K
L
V
A
T
K
L
Y
E
G
VPL
P
F
Y
Q
P
T
E
E
D
---
A
D
F
E
-------------
Q
--------------
S
M
V
L
V
A
------
C
G
P
Y
T
-
T
S
D
S
-----------
I
T
Y
D
P
L
L
D
L
I
A
V
I
N
H
D
R
---------
P
----
D
V
C
I
L
F
G
P
F
L
D
A
K
H
E
Q
V
E
N
-
C
L
L
T
S
P
F
E
D
I
F
K
Q
C
L
R
T
I
I
E
G
T
R
--------
S
S
G
S
H
L
V
F
V
P
S
LRDVHHEPVYPQ
P
P
F
S
Y
SDLS
R
E
D
K
K
Q
V
Q
F
V
S
E
P
C
S
L
S
-------
I
N
G
---
V
I
F
G
L
T
-
S
TD
L
L
F
H
--
L
G
A
E
E
I
S
S
S
S
G
T
S
D
R
F
S
R
I
L
--
K
H
I
L
T
Q
------
R
S
Y
Y
P
L
Y
P
P
Q
E
D
M
A
-----
I
-
D
Y
E
S
F
Y
V
Y
A
--
Q
L
P
V
T
P
D
V
L
-
I
I
-----
P
S
EL
R
Y
F
V
K
D
V
L
G
C
V
C
V
N
P
--------------
G
R
L
T
K
G
Q
V
G
G
T
F
A
R
L
------
Y
L
R
R
P
A
A
D
------
G
A
E
R
--
Q
S
P
C
I
A
V
Q
V
V
R
I-----------------------------------------------------------------
14
Fugue
74.96
19%
-101
- C4 -
4Y9J
4
?
A:
[1-592]
T
I
T
A
R
H
T
Q
Y
SHAKTGG
F
S
Q
T
G
P
TLHNPYKDD
P
I
L
D
R
T
L
R
R
L
L
------------
P
E
S
E
Y
M
R
V
A
A
D
L
S
K
F
G
D
R
I
T
S
E
V
E
H
L
G
R
Q
A
E
L
E
Q
P
R
L
--
E
H
Q
D
A
W
G
K
R
V
---
D
K
L
I
V
C
N
E
W
H
K
L
K
Q
I
C
A
E
E
-----
G
V
I
S
I
G
Y
E
D
S
V
D
P
F
V
R
R
I
H
Q
V
A
K
L
F
L
F
S
P
S
A
GLV
S
C
P
M
A
M
T
D
G
A
V
K
T
L
T
S
L
N
L
Y
-
G
K
H
K
L
A
T
E
A
V
D
R
L
R
S
RDPS
K
A
W
T
S
G
Q
W
M
T
EKKGGSD
V
A
G
G
C
D
T
Y
A
V
---
Q
I
D
K
D
T
Y
R
L
H
G
Y
K
W
F
S
S
A
V
D
A
D
V
A
L
T
L
A
R
I
V
D
SDG
N
A
L
E
G
SRG
L
S
L
F
L
L
K
IRDESG
N
L
N
G
I
-
Q
M
V
R
LKNKLGTKQ
L
P
T
A
E
L
L
L
D
G
A
I
A
E
R
I
G
D
Q
G
R
G
V
-
A
G
I
S
N
M
L
N
I
T
R
I
H
N
A
V
A
S
L
G
Y
M
R
R
I
I
S
L
A
R
D
Y
S
T
K
-
R
V
V
F
G
Q
T
Q
-
S
K
W
P
L
H
T
--------
T
T
L
A
K
M
E
V
------------------------
D
T
R
G
S
M
L
L
L
F
E
A
A
R
L
L
G
-------
L
S
E
A
GK
S
S
D
V
E
A
-
M
---
M
L
R
--
L
I
T
P
V
L
K
L
Y
A
G
--
K
Q
A
V
P
M
V
S
E
G
I
E
C
F
G
------
G
Q
G
Y
M
E
D
T
G
L
P
T
L
L
-----
R
-
D
A
Q
V
T
P
I
W
E
GT
T
N
V
L
S
L
D
V
L
R
V
F
SGK--
E
N
-----
I
L
L
A
F
G
K
R
V
E
Q
L
L
G
NTKTED
E
K
L
K
K
S
K
E
A
V
E
S
A
L
-----
K
Q
------
L
Q
K
L
L
V
K
A
------
S
D
S
A
I
Q
G
E
T
R
I
DSV
A
R
H
I
A
F
T
I
A
R
I
Y
S
G
A
L
L
I
D
H
A
S
DSSVAN
Q
S
D
I
E
V
A
Y
R
Y
C
CEQPLIDLRWEWFA
S
E
R
V
K
A
D
R
E
I
V
F
DNFT
13
Fugue
74.12
11%
-93
- C4 -
1UX5
-
BNI1_YEAST
A:
[1350-1760]
K
Y
P
R
P
H
K
K
L
----------------------
K
Q
L
H
W
E
K
L
D
--------------
C
T
D
N
S
I
W
G
T
G
---
K
A
E
K
F
A
D
D
L
Y
E
K
G
V
L
A
D
L
E
K
A
F
A
A
--
R
E
I
K
S
L
A
S
K
R
---
K
E
D
L
--
Q
K
I
T
F
L
S
R
D
I
S
Q
Q
-----
F
G
I
N
L
H
M
Y
S
S
L
S
V
--
A
D
L
V
K
K
-----
I
L
N
C
D
-------
R
D
F
L
Q
T
P
S
V
V
E
F
L
-
S
K
-
S
E
I
I
E
V
S
V
N
L
A
R
N
Y
A
--------
P
Y
S
T
D
W
-------
E
G
V
R
N
L
E
D
A
K
---
P
P
E
K
D
P
N
D
L
---
Q
----------
R
A
D
Q
I
Y
L
--------------
Q
L
M
V
N
L
------
E
S
Y
W
G
-
S
R
M
R
-----------
A
L
T
V
V
T
S
Y
E
R
E
Y
N
E
L
L
A
K
L
R
K
-
V
D
K
A
V
----
S
A
L
Q
E
S
D
N
L
R
N
V
F
N
V
I
L
A
V
G
N
F
M
N
D
T
S
K
Q
A
Q
G
F
K
L
-
S
T
L
Q
R
L
T
FIKDTTNS
M
T
F
L
N
Y
V
E
------------------------
K
I
V
R
L
N
Y
P
S
F
N
D
F
L
S
E
L
-------
E
P
V
---
L
D
V
V
K
V
-
S
---
I
E
Q
--
L
V
N
D
C
K
D
F
S
Q
S
I
V
N
V
E
R
S
V
E
I
G
N
L
S
D
S
S
KFHPLD
K
V
L
I
K
T
L
P
V
L
P
E
A
R
-----
K
-
K
G
D
L
L
E
D
E
V
--
K
L
T
I
M
E
F
E
S
L
M
H
T
Y
GED
S
G
-----
D
K
F
A
K
I
S
F
F
K
K
F
--------------
A
D
F
I
N
E
Y
K
-----
K
A
------
Q
A
Q
N
L
A
A
E
------
E
E
E
R
L
Y
I
K
H
--------------------------------------------------------------------------
17
Fugue
68.40
10%
-113
- C4 -
4C8Q
-
H:
[16-328]
-----------------------------------------------------------------
K
S
G
G
K
K
F
I
L
E
L
I
E
T
V
Y
E
E
I
L
D
L
E
A
N
L
------------------------
R
N
G
Q
Q
T
D
S
T
A
-----
M
W
E
A
L
H
I
D
D
S
S
Y
D
--
V
N
------
P
F
I
S
M
L
S
F
-------
D
K
G
I
K
I
M
P
R
I
F
N
F
-
L
D
-
K
Q
Q
K
L
K
I
L
Q
K
I
F
N
E
----------
L
S
H
L
Q
-------
I
I
I
L
S
S
Y
K
T
T
---
P
K
P
T
L
T
Q
L
K
---
K
V
D
L
F
Q
M
I
I
L
K
I
I
V
S
F
L
S
--------------
N
--------------------
N
-----------
S
N
F
I
E
I
M
G
L
L
L
Q
L
I
R
N
N
N
V
S
F
-
L
T
T
S
K
----
I
G
L
N
L
I
T
I
L
I
S
R
A
A
L
I
K
Q
D
S
S
P
E
I
S
T
W
N
E
I
Y
D
K
L
F
-
T
S
L
E
S
K
--------------------------------------------------
I
Q
L
I
F
P
------------------
P
R
E
-
Y
---
N
D
H
--
I
M
R
L
Q
N
M
D
E
A
Y
I
W
Q
F
L
A
S
L
A
L
------------------
K
L
N
H
Q
R
I
I
I
-----
D
-
E
V
R
D
E
I
F
A
T
--
I
N
E
A
E
--------------------------------------------------
T
L
Q
-----
I
I
------
Y
N
K
E
K
L
Y
Q
------
D
L
N
L
F
L
N
V
M
--------------------------------------------------------------------------
22
Fugue
52.60
12%
-75
- C3 -
2VDW
-
MCES_VACCW
B:
[1-287]
---
M
D
E
I
V
K
----------------------
N
I
R
E
G
T
H
V
L
-------------------------
L
P
F
Y
E
T
L
P
E
L
N
L
S
L
G
K
S
P
L
P
S
L
E
Y
G
A
--
N
Y
F
L
Q
I
S
R
V
N
---
D
L
N
R
--
M
P
T
D
M
L
K
L
F
T
H
D
I
-----
M
L
P
E
S
D
L
D
K
V
Y
E
I
--
L
K
I
N
S
V
K
Y
------------------
Y
G
R
S
T
K
A
D
A
V
-
V
A
-
D
L
S
A
R
N
K
L
---------------------------------
F
K
R
E
R
---
D
---------------------------------------------
A
I
K
S
------
T
E
N
N
L
-
Y
I
S
D
-----------
Y
K
M
L
T
F
D
V
F
R
P
L
F
D
F
V
N
E
-------------------
K
Y
C
I
I
K
L
P
T
-----------------------
L
F
G
R
G
--------
V
I
D
T
M
R
I
Y
------------------------
C
S
L
F
K
N
V
R
L
L
K
C
------------------------------------------
V
S
D
S
W
L
K
D
S
A
I
M
V
A
S
D
V
C
K
K
------
N
L
D
L
F
M
S
H
V
K
S
V
T
K
-----
S
-
S
S
W
K
D
V
N
S
V
--
Q
--
F
S
I
L
N
N
P
V
D
-----
T
E
-----
F
I
N
K
F
L
E
F
S
N
R
V
--------------
Y
E
A
L
Y
Y
V
H
-----
S
L
------
L
Y
S
S
M
T
S
D
SKSIEN
K
H
Q
R
R
L
V
K
L
L
L
------------------------------------------------------------------------
20
Fugue
41.46
16%
94
* C4 *
2KFV
-
FKBP3_HUMAN
A:
[20-92]
---------------------------------------------------------------
M
A
A
A
V
P
Q
R
A
W
T
V
E
Q
L
R
S
-----
E
Q
L
P
K
K
--
D
I
I
K
F
L
Q
E
H
G
---
S
D
S
F
--
L
A
E
H
K
L
L
G
N
I
K
N
V
A
K
T
AN
K
D
H
L
V
T
A
Y
N
H
L
F
E
--
T
K
R
F
K
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
40.75
30%
24
- C5 -
2GAA
-
YFH7_YEAST
A:
[48-110]
----------------------------------------------------------------------------
I
N
E
K
Y
H
T
F
L
S
E
H
P
N
V
--
I
E
V
N
D
R
L
K
P
M
---
V
N
L
V
--
D
S
L
K
T
L
Q
P
N
K
V
A
E
-----
M
I
E
N
Q
G
L
F
K
D
H
V
E
--
D
V
N
F
Q
P
V
K
Y
S
A
E
E
C
T
A
-------
V
V
A
R
G
G
T
A
N
A
I
R
I
-
A
A
-
S
I
N
I
A
Q
I
V
P
M
D
G
F
H
L
--------
S
R
R
C
L
D
-------
L
F
K
D
P
Q
T
A
H
K
---
R
R
G
S
P
S
T
F
D
---
S
N
N
F
L
Q
L
C
K
I
L
A
K
T
S
L
C
K
--------------
V
S
S
T
S
S
------
V
F
E
K
L
-
S
K
T
F
-----------
S
Q
T
I
P
D
I
F
V
P
G
F
N
H
A
L
K
D
P
T
P
-
D
Q
Y
C
I
----
S
K
F
T
R
I
V
I
L
E
G
L
Y
L
L
Y
D
Q
E
N
W
K
K
I
Y
K
T
L
A
D
T
G
A
L
L
-
V
Y
K
I
D
I
D
--------
Y
E
A
T
E
E
R
V
------------------------
A
K
R
H
L
Q
S
G
L
V
T
T
I
A
E
G
R
-------
E
K
F
---
R
S
N
D
L
L
-
N
---
G
R
D
--
I
D
N
H
L
I
K
V
D
N
I
V
H
I
R
N
D
H
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
39.98
30%
22
- C5 -
2GA8
-
YFH7_YEAST
A:
[48-110]
----------------------------------------------------------------------------
I
N
E
K
Y
H
T
F
L
S
E
H
P
N
V
--
I
E
V
N
D
R
L
K
P
M
---
V
N
L
V
--
D
S
L
K
T
L
Q
P
N
K
V
A
E
-----
M
I
E
N
Q
G
L
F
K
D
H
V
E
--
D
V
N
F
Q
P
V
K
Y
S
A
E
E
C
T
A
-------
V
V
A
R
G
G
T
A
N
A
I
R
I
-
A
A
-
D
S
I
N
I
A
Q
I
V
P
M
D
G
F
H
--------
L
S
R
R
C
L
-------
D
L
F
K
D
P
Q
T
A
H
---
K
R
R
G
S
P
S
T
F
---
D
S
N
N
F
L
Q
L
C
K
I
L
A
K
T
S
L
C
--------------
K
V
S
T
S
S
------
V
F
E
K
L
-
S
K
T
F
-----------
S
Q
T
I
P
D
I
F
V
P
G
F
N
H
A
L
K
D
P
T
P
-
D
Q
Y
C
I
----
S
K
F
T
R
I
V
I
L
E
G
L
Y
L
L
Y
D
Q
E
N
W
K
K
I
Y
K
T
L
A
D
T
G
A
L
L
-
V
Y
K
I
D
I
D
--------
Y
E
A
T
E
E
R
V
------------------------
A
K
R
H
L
Q
S
G
L
V
T
T
I
A
E
G
R
-------
E
K
F
---
R
S
N
D
L
L
-
N
---
G
R
D
--
I
D
N
H
L
I
K
V
D
N
I
V
H
I
R
N
D
H
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
Fugue
36.51
7%
62
- C4 -
2KBR
1
USH1C_HUMAN
A:
[1-80]
----------------------------------------------------------------
M
D
R
K
V
A
R
E
F
R
H
K
V
D
F
L
I
E
N
D
A
E
K
D
Y
L
Y
--
D
V
L
R
M
Y
H
Q
T
M
D
V
A
V
L
V
G
--
D
L
K
L
V
I
N
E
P
S
R
L
P
-----
L
F
D
A
I
R
P
L
I
P
L
K
H
--
Q
V
E
Y
D
Q
L
T
P
R
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
Fugue
36.33
9%
90
- C4 -
2L9Q
-
HSP12_YEAST
A:
[1-109]
M
S
D
A
G
R
K
G
F
----------------------
G
E
K
A
S
E
A
L
K
--------------
P
D
S
-----
Q
K
S
Y
A
E
Q
G
K
E
Y
I
T
D
K
A
D
K
V
A
G
K
V
Q
P
E
D
N
K
--
G
V
F
Q
G
V
H
D
S
A
---
E
K
G
K
--
D
N
A
E
G
Q
G
E
S
L
A
D
Q
-----
A
R
D
Y
M
G
A
A
K
S
K
L
N
--
D
A
V
E
Y
V
S
G
R
V
H
G
E
E
D
P
-------
T
K
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
36.23
25%
-57
- C5 -
1XRK
2
BLE_STRHI
A:
[2-68]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
K
L
T
--------
S
A
V
P
V
L
T
A
------------------------
R
D
V
A
E
A
V
E
F
W
T
D
R
L
G
F
S
RVFVEDD
F
A
G
---
V
V
R
D
D
V
-
T
---
L
F
I
S
A
V
Q
D
Q
V
V
P
D
N
T
Q
A
W
V
W
V
R
G
L
D
E
L
Y
A
E
W
S
E
------
V
V
S
T
N
F
R
D
A
S
G
P
A
M
-----
T
-
E
I
V
E
Q
P
W
G
R
--
E
F
A
L
R
D
P
A
G
N
C
V
-----
H
F
-----
V
A
E
---------------------------------------------------------------------------------------------------------------------------------------------
6
HHSearch
35.20
9%
-140
- C- -
3B5D
1
EMRE_ECOLI
A:
[30-105]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
W
---
P
S
V
G
T
I
I
C
Y
C
A
S
F
W
L
L
A
Q
--------------
T
L
A
Y
I
P
------
T
G
I
A
Y
A
I
W
-
S
-----------
G
V
G
I
V
L
I
S
L
L
S
W
G
F
F
G
Q
R
L
D
L
-
P
A
I
I
G
----
M
M
L
I
C
A
G
V
L
I
I
N
L
L
S
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
HHSearch
34.97
14%
-269
- C- -
3B5D
1
EMRE_ECOLI
A:
[34-105]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
G
T
I
I
C
Y
C
A
S
F
W
------
L
L
A
Q
T
L
A
Y
I
P
T
G
I
A
-----
Y
A
I
W
S
G
V
G
I
V
L
--
I
S
L
L
S
W
G
F
F
G
Q
R
-----
L
D
-----
L
P
A
I
I
G
M
M
L
I
C
A
--------------
G
V
L
I
I
N
L
L
-----
S
--------------------------------------------------------------------------------------------------------
15
Fugue
17.47
46%
629
- C1 -
2BTA
1
?
?:
[1-15]
-------------------------------------------------------------------------
M
E
E
L
Q
D
D
Y
E
D
M
M
E
E
N
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
HHSearch
13.46
6%
271
- C5 -
2JO1
-
PLM_HUMAN
A:
[23-40]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
A
G
I
L
F
I
L
--------------
G
I
L
I
V
L
S
R
-----
R
C
------
R
C
K
F
N
Q
Q
Q
------
R
T
G
E
P
D
E
E
E
G
T
------------------------------------------------------------------------
12
HHSearch
10.51
20%
394
* C5 *
2ZXE
-
?
G:
[26-42]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
A
A
V
L
C
V
I
--------------
G
I
I
I
L
L
A
G
-----
K
--------------------------------------------------------------------------------------------------------
10
HHSearch
9.51
20%
285
- C5 -
2JP3
-
FXYD4_RAT
A:
[24-43]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
G
G
L
L
C
I
A
--------------
G
I
A
L
A
L
S
G
-----
K
C
------
K
C
R
R
N
H
T
P
------
S
S
L
P
E
K
V
T
P
L
I
------------------------------------------------------------------------
11
HHSearch
6.11
5%
473
- C5 -
3WGU
1
?
G:
[34-48]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
A
L
A
F
I
V
--------------
G
L
I
I
I
L
S
K
--------------------------------------------------------------------------------------------------------------