@TOME V2.2
(Nov 2016)
Ref.
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : S36A2_HUMAN: (2015-12-10 )
MSVTKSTEGPQGAVAIKLDLMSPPESAKKLENKDSTFLDESPSESAGLKKTKGITVFQALIHLVKGNMGTGILGLPLAVKNAGILMGPLSLLVMGFIACHCMHILVKCAQRFCKRLNKPFMDYGDTVMHGLEANPNAWLQNHAHWGRHIVSFFLIITQLGFCCVYIVFLADNLKQVVEAVNSTTNNCYSNETVILTPTMDSRLYMLSFLPFLVLLVLIRNLRILTIFSMLANISMLVSLVIIIQYITQEIPDPSRLPLVASWKTYPLFFGTAIFSFESIGVVLPLENKMKNARHFPAILSLGMSIVTSLYIGMAALGYLRFGDDIKASISLNLPNCWLYQSVKLLYIAGILCTYALQFYVPAEIIIPFAISRVSTRWALPLDLSIRLVMVCLTCLLAILIPRLDLVISLVGSVSGTALALIIPPLLEVTTFYSEGMSPLTIFKDALISILGFVGFVVGTYQALDELLKSEDSHPFSNSTTFVR
Atome Classification :
(17 SA)
-.........10.........20........30...----------.-....40......-..50---------...----------.....60....------------....70.-.......-80--------..------------------------..-----------------------....90......---..100-.......------110--.....-...---------120.......130.......140....-.--.---------------------------.150....---..-.160---.....----....170.......180.......190.......200.......210..---------------.....220.......230-.--......240...-------....---250.....--..260...-....270...------------....280.....-..290-.-----..-....300----......-.310---.........320......-------.330..---.------------------------....340.------------......350.......--------360.......370...-.-------...380.......390--..-......400.......-410...-----.--....420.......-430-........440.......450.......460.......470---........480.--------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-MSVTKSTEGP-Q
G
A
V
A
I
K
L
D
LMSP
P
E
S
A
K
K
LENKD----------S-TFLDESPSESAG-LKKT---------K
G
I
----------
T
V
F
Q
A
L
I
H
L
VK------------GNMGTGI-LGL
P
L
A
V-KN--------A
G
------------------------
I
L
-----------------------
M
G
P
L
S
L
L
V
M
G
F
I
---
A
C
H
C
M
-
H
I
L
V
K
C
A
------
Q
R
---
F
C
K
R
L-N
K
P
---------
F
MDY
G
D
T
V
M
HGLEAN
P
N
A
W
L
Q
N
H
A
H
W
G
-
R
--
H
---------------------------
I
V
S
F
F
L
I
I
---
T
Q
-
L
G
-----
F
C
C
V
Y
----
I
V
F
L
A
D
N
L
K
Q
V
V
E
A
V
NSTTNNCYSN
E
T
V
I
L
TPTMDS
R
L
Y
M
L
S
F
L
P
F
L
V
L
---------------
L
V
L
I
RN
L
R
I
L
T
I
F
S
M
L
A
N
-
I
--
S
M
L
V
S
L
V
I
I
I
Q
Y
-------
I
T
Q
E---IPDPSR
L
P
--
L
V
ASWKT
Y
-
P
L
F
F
G
T
A
IF
S
------------
F
E
S
I
G
V
V
LPL
E
N
-KMKNA-R-----H
F
-
P
A
I
L
S
L
G
----
M
S
I
V
T
S
-
L
Y
-----
I
G
M
A
A
L
G
Y
L
RFGDD
I
K
A
S
-------
I
S
LNLP---
N
------------------------
C
W
L
Y
Q
S
V
K
------------
L
L
Y
I
A
G
I
L
C
T
Y
A
L
Q
F
Y--------VP
A
E
I
I
I
P
F
A
ISRVST-R-------WALPL
D
L
S
I
R
L
V
M
V
C
---
L
T
-
C
L
L
A
I
L
I
P
R
L
D
L
V
I
S
L
-
V
G-SVS-----G--
T
A
L
A
L
IIP
P
L
L
E
V
T
-
T
F
--
Y
SEGM
S
P
L
T
I
F
K
D
A
L
I
S
I
L
G
F
V
G
F
V
V
G
T
Y
Q
A
L
D
E
L
L
K
SED----SHPFSNSTTFVR--------------------------------------------------------------------------------
13
Fugue
96.22
14%
-140
- C2 -
1QI9
-
PRXV_ASCNO
A:
[2-556]
T
C
S
T
S
D
D
A
D
D
P
-
T
P
P
N
E
R
D
D
E
A
F
A
S
R
V
A
A
A
K
R
E
L
E
G
T
G
T
V
C
Q
I
N
NG
E
-
T
------
D
L
A
A
K
-
F
H
K
S
LPHDDLGQV-
D
A
----------
D
A
F
A
A
L
E
D
C
I
L
N
GD
L
S
I
C
E
D
VPV
G
N
S
E
-----------------------
G
DPVGRLVNPTAAFAIDISGPAFSA
T
T
-----------------------
I
P
P
V
P
T
L
P
S
P
E
L
---
A
A
Q
L
A
-
E
V
Y
W
M
A
L
A
RDVPF
M
Q
---
Y
G
----
T
D
D
---------
I
T
V
T
A
A
A
N
L
A
G
M
E
G
F
P
N
---------
L
-
D
--
A
V
S
I
G
SDGTVDPLSQLFRATFVGVETGP
F
I
S
Q
L
L
V
N
---
S
F
-
T
I
-----
D
---------------------------
S
I
T
V
E
P
K
Q
E
T
F
A
P
D
V
N
---
Y
M
V
D
F
D
E
W
L
N
I
Q
N
GGPPAGPELLDD
E
L
R
F
V
R
N
A
R
D
L
A
R
V
T
F
T
D
N
-
I
N
T
E
A
Y
R
G
A
L
I
L
L
G
L
DAFNRAG
V
N
G
P
---
F
I
D
I
D
-----
R
Q
A
G
F
V
N
F
G
I
S
H
Y
F
R
L
I
G
A
------------
A
E
-
L
A
Q
R
S
S
W
Y
Q
-
K
W
Q
V
H
-
R
-----
F
A
R
P
E
A
L
G
G
T
----
L
H
L
T
I
K
-
G
-ELNAD
F
D
L
S
L
L
E
N
A
E
L
L
K
R
V
A
A
I
-------
N
A
A
Q
N
P
---
N
NEVTYLLPQAIQEGSPTHPSYPS
G
H
A
T
Q
N
G
A
F
------------
A
T
V
L
K
A
L
I
G
L
D
R
G
G
D
C
--------
Y
P
D
P
V
Y
P
D
D
D
G
L
K
L
I
D
F
R
--------
G
S
C
L
T
F
E
G
E
I
N
K
L
A
---
V
N
-
V
A
F
G
R
Q
M
L
G
I
H
Y
R
F
D
G
-
I
Q
-
G
L
L
-----
L
--
G
E
T
I
T
V
R
T
L
H
Q
E
L
M
-
T
F
--
A
E
E
S
T
F
E
F
R
L
F
T
G
E
V
I
K
L
F
Q
D
G
T
F
T
I
D
G
F
K
C
--------
P
----
G
L
V
Y
T
G
V
E
N
C
V
---------------------------------------------------------------------------------
11
Fugue
83.16
14%
-120
- C2 -
4C0E
-
?
A:
[9-528]
-
L
E
A
A
H
L
L
E
-
Q
M
E
Y
V
F
D
E
W
I
H
L
C
N
N
P
H
A
----
T
E
R
A
----------
A
M
I
F
V
H
Q
L
H
S
V
Q
L
V
-
T
N
R
D
---------
E
F
L
----------
L
F
L
R
H
A
L
D
K
S
V
------------
E
R
F
E
Q
G
I
-
H
S
G
A
S
I
A
-
E
S
--------
F
Q
------------------------
A
V
-----------------------
E
A
L
V
K
L
I
I
I
F
V
K
SHS
A
A
V
A
F
M
D
S
I
L
A
L
G
------
V
L
---
V
A
N
S
H
-
H
V
K
RGENFN
Q
R
V
F
Y
R
F
F
A
L
L
L
H
E
V
G
L
L
A
G
H
F
--
S
K
S
H
Y
E
-
Q
--
I
---------------------------
I
L
N
F
A
A
R
L
---
F
D
M
R
-------------------
P
N
L
L
P
G
F
A
C
A
W
A
G
L
V
S
H
R
A
F
L
P
V
I
L
G
L
P
D
E
K
G
W
A
P
F
T
K
L
L
E
Q
F
-
L
---------------
G
C
V
G
E
L
V
K
T
F
T
V
S
S
L
G
K
E
M
Y
--
H
A
A
L
K
I
L
I
V
L
Q
H
-------
D
F
P
I
---
Y
L
D
K
F
R
V
Q
--
L
C
Q
S
L
P
L
H
-
A
T
Q
L
V
N
L
I
L
A
AIPPNCNSLADP
F
Q
A
G
L
K
V
D
K
I
P
D
M
K
E
R
P
P
-
T
-----
A
F
-
D
S
A
G
L
L
R
E
A
GL
L
D
I
L
E
R
M
L
Q
-----
N
G
P
S
E
D
G
V
A
Q
I
N
H
A
I
N
K
S
-------
T
S
F
G
Y
V
---
P
---------------------------------------------------
L
G
V
N
R
R
L
I
D
--------
A
V
V
A
R
F
A
E
F
A
I
N
R
A
S
S
-
R
-------
S
D
S
A
I
F
V
A
G
A
N
D
I
K
T
---
L
Q
M
L
V
T
E
V
S
P
E
A
R
Y
Y
L
V
S
S
M
V
N
-
E
L
R
YPN
A
Y
T
--
N
Y
F
S
Q
A
L
L
D
I
F
G
H
D
M
S
D
--
P
E
E
N
L
V
R
E
Q
I
V
R
V
L
L
E
R
V
L
G
Y
W
P
Q
P
W
G
L
I
I
T
I
L
E
L
L
K
N
D
K
YLFF
E
L
P
F
I
K
A
T
P
E
V
A
E
R
F
T
A
L
A
R
S
AA---------------------------------------------------------------------
1
HHSearch
82.04
12%
-151
- C2 -
3L1L
2
ADIC_ECO57
A:
[7-380]
----------------------------------------------------------------
A
---------
H
K
V
----------
G
L
I
P
V
T
L
M
V
S
G
------------
A
I
M
G
S
G
V
-
F
L
L
P
A
N
L
-
A
S
--------
T
G
------------------------
G
------------------------
I
A
I
Y
G
W
L
V
T
I
I
G
---
A
L
G
L
S
-
M
V
Y
A
K
M
S
------
F
L
---
D
P
S
---
P
G
G
---------
S
Y
A
Y
---
A
R
-----------
R
C
F
G
P
F
L
-
G
--
Y
---------------------------
Q
T
N
V
L
Y
W
L
---
A
C
-
W
I
-----
G
N
I
A
M
----
V
V
I
G
V
G
Y
L
S
Y
F
F
P
I
L
K
D
---------------
P
-
W
V
L
T
I
T
C
V
V
V
L
W
I
F
V
---------------
L
L
N
I
V
G
P
K
M
I
T
R
V
Q
A
V
A
T
-
V
--
L
A
L
I
P
I
V
G
I
A
V
F
-------
G
W
F
W
---
F
R
G
E
T
Y
M
A
--------
A
I
-
Q
S
T
L
N
V
T
L
W
S
------------
F
I
G
V
E
S
A
S
V
A
A
G
-
V
V
K
N
P
K
R
-----
N
V
-
P
I
A
T
I
G
G
----
V
L
I
A
A
V
-
C
Y
-----
V
L
S
T
T
A
I
M
G
M
I
P
N
A
A
L
R
V
SASP
F
G
D
A
A
R
M
A
L
---
G
------------------------
D
T
A
G
A
I
V
S
------------
F
C
A
A
A
G
C
L
G
S
L
G
G
W
T
L
--------
L
A
G
Q
T
A
K
A
A
A
D
D
G
L
F
P
-
P
IFARVNK
A
G
T
P
V
A
G
L
I
I
V
G
I
L
M
---
T
I
-
F
Q
L
S
S
I
S
P
N
A
T
K
E
F
G
L
-
V
S
-
S
V
S
-----
V
I
F
T
L
V
P
Y
L
Y
T
C
A
A
L
L
L
-
L
G
--
H
G
H
F
G
K
A
R
P
A
Y
L
A
V
T
T
I
A
F
L
Y
C
I
W
A
V
V
G
S
G
A
K
E
V
M
W
S
F
V
T
----
L
M
V
I
T
A
M
Y
A
L
N
Y
--------------------------------------------------------------------------------
18
Fugue
81.75
11%
-137
- C2 -
1QI9
-
PRXV_ASCNO
A:
[2-556]
T
C
S
T
S
D
D
A
D
D
P
-
T
P
P
N
E
R
D
D
E
A
F
A
S
R
V
A
A
A
K
R
E
L
E
G
T
G
--------
T
-
V
C
Q
I
N
N
G
E
T
D
L
A
-
A
K
F
H
---------
K
S
L
PHDDLGQVD
A
D
A
F
A
A
L
E
D
C
I
L
------------
N
G
D
L
S
I
C
-
E
D
V
P
V
G
N
-
S
E
--------
G
D
------------------------
P
V
GRLVNPTAAFAIDISGPAFSA
T
T
I
P
P
V
P
T
L
P
S
P
E
L
---
A
A
Q
L
A
-
E
V
Y
W
M
A
L
------
A
R
DVP
F
M
Q
Y
G
-
T
D
D
---------
I
T
V
T
A
A
A
N
L
A
G
M
E
G
F
P
N
L
D
A
V
S
I
G
S
D
G
-
T
VD
P
---------------------------
L
S
Q
L
F
R
A
T
FVG
V
E
-
T
G
PFISQ
L
L
V
N
S
----
F
T
I
D
S
I
T
V
E
P
K
Q
E
T
F
A
P
D
V
N
Y
M
V
D
F
D
E
W
L
N
I
Q
N
G
G
P
P
A
G
P
E
L
L
D
D
E
L
R
F
---------------
V
R
N
A
R
D
L
A
R
V
T
F
T
D
N
I
N
T
-
E
--
A
Y
R
G
A
L
I
L
L
G
L
D
-------
A
F
N
R
AGV
N
G
P
F
I
D
I
D
--
R
Q
A
G
F
V
N
F
-
G
I
S
H
Y
F
R
L
I
G
------------
A
A
E
L
A
Q
R
S
S
W
Y
Q
-
K
W
Q
V
H
-
R
FAR
P
E
A
L
-
G
G
T
L
H
L
T
----
I
K
G
E
L
N
-
A
D
-----
F
D
L
S
L
L
E
N
A
E
L
L
K
R
V
A
A
I
-------
N
A
A
Q
N
P
---
N
NEVT--------------------
Y
L
L
P
Q
A
I
Q
EGSPTHPSYPS
G
H
A
T
Q
N
G
A
F
A
T
V
L
K
A
L
I
G
L
D
R
G
G
DC
Y
P
D
P
V
Y
P
D
D
D
G
L
K
L
I
D
-
F
-------
R
G
S
C
L
T
F
E
G
E
I
N
K
L
A
---
V
N
-
V
A
F
G
R
Q
M
L
G
I
H
Y
R
F
D
G
-
I
Q
-
G
L
L
-----
L
--
G
E
T
I
T
V
R
T
L
H
Q
E
L
M
-
T
F
--
A
E
E
S
T
F
E
F
R
L
F
T
G
E
V
I
K
L
F
Q
D
G
T
F
T
I
D
G
F
K
C
--------
P
----
G
L
V
Y
T
G
V
E
N
C
V
---------------------------------------------------------------------------------
2
HHSearch
74.75
13%
-146
- C2 -
3GIA
5
Y609_METJA
A:
[3-306]
--------------------------------------------------------------
L
K
N
---------
K
K
L
----------
S
L
W
E
A
V
S
M
A
V
G
------------
V
M
I
G
A
S
I
-
F
S
I
F
G
V
G
A
K
I
--------
A
G
-------------------------
R
-----------------------
N
L
P
E
T
F
I
L
S
G
I
Y
---
A
L
L
V
A
-
Y
S
Y
T
K
L
G
------
A
K
---
I
V
S
---
N
A
G
---------
P
I
A
F
---
I
-----------
H
K
A
I
G
D
N
I
I
T
--
G
---------------------------
A
L
S
I
L
L
W
M
---
S
Y
-
V
I
-----
S
I
A
L
F
----
A
K
G
F
A
G
Y
F
L
P
L
I
N
A
P
I
N
---------------
T
-
F
N
I
A
I
T
E
I
G
I
V
A
F
F
T
---------------
A
L
N
F
F
G
S
K
A
V
G
R
A
E
F
F
I
V
-
L
--
V
K
L
L
I
L
G
L
F
I
F
A
-------
G
L
I
T
---
I
H
P
S
Y
V
I
P
DL
A
P
S
A
V
S
G
M
-
I
F
A
S
A
I
F
F
L
S
------------
Y
M
G
F
G
V
I
T
N
A
S
E
-
H
I
E
N
P
K
K
-----
N
V
-
P
R
A
I
F
I
S
----
I
L
I
V
M
F
-
V
Y
-----
V
G
V
A
I
S
A
I
G
N
L
P
I
D
E
L
I
K
A
SEN
A
--
L
A
V
A
A
K
PFL
G
------------------------
N
L
G
F
L
L
I
S
------------
I
G
A
L
F
S
I
S
S
A
M
N
A
T
I
Y
--------
G
G
A
N
V
A
Y
S
L
A
K
D
G
E
L
P
-
E
-------
F
F
E
R
K
V
W
F
K
S
T
E
G
L
Y
---
I
T
-
S
A
L
G
V
L
F
A
L
L
F
N
M
E
G
V
-
A
S
-
I
T
S
-----
A
--
V
F
M
V
I
Y
L
F
V
I
L
S
H
Y
-
I
L
--
I
D
E
V
G
G
R
K
E
I
V
I
F
S
F
I
V
V
L
G
V
F
L
L
L
L
Y
Y
Q
W
I
T
N
R
F
V
F
Y
G
I
----
I
A
T
F
I
G
V
L
I
F
E
I
--------------------------------------------------------------------------------
12
Fugue
63.83
10%
-145
- C2 -
1MIO
1
NIFK_CLOPA
B:
[2-458]
--------------------------------------------------------
L
D
A
T
-
P
K
E
I
---------
V
--------------
E
R
K
------------------------------------ALRINPAK
T
C
------------------------
Q
P
-----------------------
V
G
A
M
-
Y
A
A
L
G
I
H
N--
C
L
P
H
S
-
H
G
S
Q
G
C
C
------
S
Y
---
H
R
T
V
L
S
-
R
H
---------
F
K
E
P
A
M
A
S
T
S
S
F
T
-
E
G
A
S
V
F
G
G
G
S
N
I
K
-
T
--
A
---------------------------
V
K
N
I
F
S
L
Y
---
N
--
P
D
-----
I
I
A
V
H
T
T
C
L
S
E
T
L
G
D
D
L
P
T
Y
I
S
Q
M
E
D
A
G
S
I
-
P
E
G
K
L
V
I
H
T
N
T
P
S
Y
V
G
-
S
H
V
T
G
F
A
N
M
V
---------------
Q
G
I
V
N
Y
L
S
E
N
T
G
A
------
K
--
N
G
K
I
N
V
I
P
G
F
V
--------
G
P
A
D
---
M
R
E
I
K
R
L
F
--
E
A
M
D
I
P
Y
I
-
M
F
P
D
T
S
G
V
L
D
------------
G
P
T
T
G
E
Y
K
M
Y
P
E
-
G
G
T
K
I
-
E
-----
D
L
-
K
D
T
G
N
S
D
----
L
T
L
S
L
G
-
S
Y
-----
A
S
D
L
G
A
K
T
L
E
K
K
C
K
V
P
-
F
-------
K
T
L
R
T
P
---
I
------------------------
G
V
S
A
T
D
E
F
------------
I
M
A
L
S
E
A
T
G
K
-----
E
--------
V
P
A
S
I
E
E
E
R
G
Q
L
I
D
L
M
-
I
-------
D
A
Q
Q
Y
L
Q
G
K
K
V
A
L
L
G
D
P
D
E
I
-
I
A
L
S
K
F
I
I
E
L
G
A
I
P
K
Y
-
V
V
T
G
T
P
-----
G
--
M
K
F
Q
K
E
I
D
A
M
L
A
E
A
-
G
-IE--------------------------------------
G
S
----
K
V
K
V
E
G
D
F
F
D
V
H
Q
W
I
K
N
EGVD
L
L
I
S
N
TYG
K
F
I
A
R
E
E
N
I
P
F
V
R
F
G
FPIMDRYGHYYNPKVG
Y
K
G
A
I
R
L
V
E
E
I
T
N
V
I
L
D
K
I
E
R
ECTEEDFEVVR
10
Fugue
43.50
21%
33
- C2 -
1PGY
-
A:
[1-47]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
L
V
D
-
E
V
K
D
M
-
E
------
I
-
A
R
L
M
S
L
G
----
L
S
I
E
E
A
-
T
E
-----
F
Y
E
N
D
V
T
Y
E
R
Y
L
E
I
L
K
S
K
-------
Q
K
E
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
Fugue
41.68
18%
101
- C2 -
4XO2
-
GNSA_ECOLI
A:
[1-60]
----------------------
M
N
I
E
E
L
K
K
Q
A
E
T
E
I
----------
A
-
D
F
I
A
Q
K
I
A
E
----
L
N
K
N
---------
T
G
K
----------
E
V
S
E
I
R
F
T
A
R
E
------------
K
M
T
G
L
E
S
-
Y
D
V
K
I
K
I
-
M
L
--------
E
H
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
HHSearch
39.78
10%
-114
- C2 -
2JLN
-
?
A:
[21-185]
-------------------------------------------------------------
R
Y
A
E
---------
R
S
V
----------
G
P
F
S
L
A
A
I
W
F
A
------------
M
A
I
Q
V
A
I
F
I
A
A
G
Q
M
T
-
S
S
--------
F
Q
------------------------
V
W
-----------------------
Q
V
I
V
A
I
A
A
G
C
T
I
---
A
V
I
L
L
-
F
F
T
Q
S
A
A
------
I
R
---
W
-----------------
G
I
N
F
T
V
A
A
R
-----------
M
P
F
G
I
R
G
-
S
--
L
---------------------------
I
P
I
T
L
K
A
L
---
L
S
-
L
F
-----
W
F
G
F
Q
----
T
W
L
G
A
L
A
L
D
E
I
T
R
L
L
T
G
F
---------------
T
N
L
P
L
W
I
V
I
F
G
A
I
Q
V
V
---------------
T
T
-
F
Y
G
I
T
F
I
R
W
M
N
V
F
A
S
-
P
--
V
L
L
A
M
G
V
Y
M
V
Y
L
-------
M
L
D
G
---
A
D
V
S
L
G
E
V
--
M
S
M
G
G
E
N
P
-
G
M
P
F
S
T
A
I
M
I
------------
F
V
G
G
W
I
A
V
V
V
S
I
-
H
D
I
V
K
-
E
-----
C
K
-
V
D
P
N
A
S
R
----
E
G
Q
T
K
A
-
D
A
-----
R
Y
A
T
A
Q
W
L
G
M
V
P
A
S
I
I
F
G
-------
F
I
G
A
A
S
---
M
------------------------
V
L
V
G
E
W
N
P
------------
V
I
A
I
T
E
V
V
G
G
V
S
I
P
M
A
--------
I
L
F
Q
V
F
V
L
L
A
T
W
S
T
N
P
-
A
-------
A
N
L
L
S
P
A
Y
T
L
C
S
T
F
P
---
R
V
-
F
T
F
K
T
G
V
I
V
S
A
V
V
G
L
L
-
M
M
-
P
W
Q
-----
F
--
A
G
V
L
N
T
F
L
N
L
L
A
S
A
-
L
G
--
P
L
A
G
I
M
I
S
D
Y
F
L
V
R
R
R
R
I
S
L
H
D
L
Y
R
T
K
G
I
Y
T
Y
W
R
G
V
N
W
V
A
----
L
A
V
Y
A
V
A
L
A
V
S
F
--------------------------------------------------------------------------------
14
Fugue
39.29
11%
238
- C2 -
4JZP
1
BAP31_HUMAN
A:
[4-55]
-----
D
V
G
N
A
E
-
V
K
L
E
E
E
N
R
S
L
K
A
D
L
Q
K
L
K
D
E
L
A
S
T
----------
K
-
Q
K
L
E
K
A
E
N
Q
V
L
A
M
R
K
Q
S
---------
E
G
L
----------
T
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
Fugue
35.85
13%
209
- C2 -
2KHK
-
ATPF_ECOLI
A:
[1-53]
----
M
A
A
I
E
K
R
-
Q
K
E
I
A
D
G
L
A
S
A
E
R
A
H
K
D
L
D
L
A
K
A
S
----------
A
-
T
D
Q
L
K
K
A
K
A
E
A
Q
-
V
I
I
E
---------
Q
A
N
----------
K
R
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
Fugue
35.50
16%
340
* C2 *
1WFB
1
ANPA_PSEAM
A:
[1-37]
--------------------
D
T
A
S
D
A
A
A
A
A
A
L
T
A
A
N
----------
A
-
K
A
A
A
E
L
T
A
A
N
A
A
-
A
A
A
A
---------
A
T
A
----------
R
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
HHSearch
31.39
9%
-71
- C2 -
3DH4
1
?
A:
[52-173]
---------------------------------------------------------------
A
G
---------
K
S
L
----------
P
W
W
A
V
G
A
S
L
I
A
------------
A
N
I
S
A
E
Q
F
I
G
M
S
G
S
G
-
Y
S
--------
I
G
------------------------
L
A
-----------------------
I
A
S
-
Y
E
W
M
S
A
I
T
---
L
I
I
V
G
-
K
Y
F
L
P
I
F
------
I
E
----------
K
G
---------
I
Y
T
I
P
E
F
V
E
-----------
K
R
F
N
K
K
L
-
K
--
T
---------------------------
I
L
A
V
F
W
I
S
L
--
Y
I
-
F
V
-----
N
L
T
S
V
----
L
Y
L
G
G
L
A
L
E
T
I
L
G
I
--------------------
P
L
M
Y
S
I
L
G
L
A
L
F
A
L
V
---------------
Y
S
I
------
V
V
W
T
D
V
I
Q
V
-
F
--
F
L
V
L
G
G
F
M
T
T
Y
M
-------
A
V
S
F
---
I
G
G
T
D
G
W
F
--
A
G
V
S
K
M
V
D
-
A
A
P
G
H
F
E
M
I
L
------------
D
Q
S
N
P
Q
Y
M
N
L
P
G
-
I
A
V
L
I
-
G
-----
G
L
-
W
V
A
N
L
Y
Y
----
W
G
F
N
Q
Y
-
I
I
-----
Q
R
T
L
A
A
K
S
V
S
E
A
Q
K
G
I
V
F
-------
A
A
F
L
K
L
---
I
------------------------
V
P
F
L
V
V
L
P
------------
G
I
A
A
Y
V
I
T
S
D
P
Q
L
M
A
S
--------
L
G
D
I
A
A
T
N
L
P
S
A
A
N
A
D
-
K
-------
A
Y
P
W
L
T
Q
F
L
P
V
G
V
K
G
---
V
V
-
F
A
A
L
A
A
A
I
V
S
S
L
A
S
M
L
-
N
S
-
T
A
T
-----
I
--
F
T
M
D
I
Y
K
E
Y
I
S
P
D
S
-
G
D
--
H
K
L
V
N
V
G
R
T
A
A
V
V
A
L
I
I
A
C
L
I
A
P
M
L
G
G
I
G
Q
A
F
Q
Y
I
Q
E
Y
T
G
----
L
V
S
P
G
I
L
A
V
F
L
L
--------------------------------------------------------------------------------
7
HHSearch
26.38
15%
581
* C3 *
2XNS
1
RGS14_HUMAN
C:
[11-30]
--
R
V
Q
S
S
G
A
H
D
-
Q
R
G
L
L
S
N
E
E
V
F
R
A
L
R
D
F
D
R
W
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
HHSearch
23.19
21%
578
- C1 -
1TER
1
TERT_APIME
A:
[7-20]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
I
I
I
P
H
M
C
W
K
K
-
C
G
--
K
K
--------------------------------------------------------------------------------------------------------------------------------------
9
HHSearch
20.14
25%
946
- C3 -
2OM2
1
RGS14_HUMAN
B:
[11-26]
--
R
V
Q
S
S
G
A
H
D
-
Q
R
G
L
L
R
K
E
D
L
V
L
P
E
F
L
Q
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
Fugue
19.25
20%
202
- C2 -
2JXF
-
?
A:
[1-30]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
T
N
W
Q
K
L
E
V
F
W
A
-
K
--
H
---------------------------
M
W
N
F
I
S
G
I
---
Q
Y
-
L
A
-----
G
L
S
T
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------