@TOME V2.2
(Nov 2016)
Ref.
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : S36A3_HUMAN: (2015-12-10 )
MSLLGRDYNSELNSLDNGPQSPSESSSSITSENVHPAGEAGLSMMQTLIHLLKCNIGTGLLGLPLAIKNAGLLVGPVSLLAIGVLTVHCMVILLNCAQHLSQRLQKTFVNYGEATMYGLETCPNTWLRAHAVWGRYTVSFLLVITQLGFCSVYFMFMADNLQQMVEKAHVTSNICQPREILTLTPILDIRFYMLIILPFLILLVFIQNLKVLSVFSTLANITTLGSMALIFEYIMEGIPYPSNLPLMANWKTFLLFFGTAIFTFEGVGMVLPLKNQMKHPQQFSFVLYLGMSIVIILYILLGTLGYMKFGSDTQASITLNLPNCWLYQSVKLMYSIGIFFTYALQFHVPAEIIIPFAISQVSESWALFVDLSVRSALVCLTCVSAILIPRLDLVISLVGSVSSSALALIIPALLEIVIFYSEDMSCVTIAKDIMISIVGLLGCIFGTYQALYELPQPISHSMANSTGVHA
Atome Classification :
(17 SA)
.........10........20........30........40....--....-------50....--....60.....-....70........80........90...---.....100-.------------------.....--------.110.......120------..--.....130..-.....140..-.....150--.-......160.......----170.......180...---....190.......200..------------.....210.......220.......230..--.....240...--....250.......260-........270.......280.-..---.....290......-----.300----.......310....-------...320---..---.....330.....----------..340........350..--.....360.-----..----..---..370.......380.......390.......-----------------400.--......410..-----.....420-----....--....430-----.........440...-----------...------------.450.......460....--...470-----------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MSLLGRDYN
S
E
LNSLDNGPQSPSESSSSITSENVHPA
G
E
A
G
L
S
M
M
--
Q
T
L
I
-------
H
L
L
K
CN--IGTGL-LGL
P
L
-
A
IKNA
G
L
L
V
G
P
V
S
L
L
A
I
G
V
L
T
V
H
C
M
V
I
L
L
---
N
C
A
Q
H
L
S
Q
-
R
------------------
L
Q
K
T
F
--------VNYG
E
A
T
M
YGLETC------
P
N
--
T
W
L
R
A
H
AVW
G
-
R
Y
T
V
S
F
L
L
V
I
-
T
QL
G
F
C
S
V
--
Y
-
F
M
F
M
A
D
N
L
Q
Q
M
V
E
K
A
H
----VTSNICQP
R
E
I
L
T
LTP---
I
L
D
I
R
F
Y
M
L
I
I
L
P
F
L
I
L
L
V
------------
F
I
QN
L
K
V
L
S
V
F
S
T
L
A
N
I
T
T
L
G
S
M
A
L
I
F
E
Y
I
--
M
EGIPYPSNL
P
--
L
MAN
W
K
T
F
L
L
F
FG
T
A
I
--
F
T
FEG
V
G
M
V
LP
L
K
N
QMKH
P
-
Q
Q
-
F
S
---
F
V
L
Y
L
G
M
S
I
V
I
I
L
Y
-----
I
L
L
G
----
T
L
G
Y
M
KFGSDT
Q
A
S
-------
I
T
LNLP---
N
C
---
W
L
Y
Q
S
V
K
L
M
Y
S
I
G
----------
I
F
F
-
T
Y
A
L
Q
FHVP
A
E
I
I
I
--
P
F
A
I
S
Q
VSE-----S
W
----
A
L
---
F
V
D
L
S
V
R
S
A
L
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C
L
T
C
V
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A
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P
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D
L
V
I
S
L
V
G
-----------------
S
VS
S
--
S
A
L
A
L
I
I
P
A
L
L
-----
E
I
V
I
FYS------EDM
S
--
C
V
T
I
A
-------
K
D
I
M
I
S
I
V
G
L
L
G
C
I
F
-----------
G
T
Y
------------
Q
A
L
Y
ELPQ
P
I
S
H
S
MANST--GVHA-------------------------------------------------------------------------------------------------------
11
Fugue
84.27
14%
-126
- C3 -
2FUG
-
?
?:
[7-438]
---
S
G
L
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P
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E
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A
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-------
E
E
V
K
-----
R
S
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-
R
G
R
G
G
-
A
G
F
P
T
G
L
K
W
S
F
M
P
-----------------------
K
D
D
G
-
K
------------------
Q
H
Y
L
I
--------
C
N
A
D
E
S
E
P
G
S
F
K
D
R
------
Y
I
--
L
E
D
V
P
H
L
L
I
E
-
G
M
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A
G
Y
A
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-
A
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RG
E
-
Y
R
R
A
A
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A
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A
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GY
L
G
K
N
L
F
G
T
D
F
S
F
D
L
H
V
---
H
R
G
A
G
A
Y
I
C
G
E
E
T
A
L
M
N
S
L
E
GLRANPRLKPP
F
P
A
Q
S
G
L
W
G
K
P
T
T
I
N
N
V
E
T
L
A
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E
R
G
--
A
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F
A
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M
G
T
E
Q
--
S
K
----------
G
M
K
L
--
Y
Q
I
S
G
---------
P
V
K
R
P
-
G
---
V
---
Y
E
L
P
M
G
T
T
F
R
E
L
I
Y
-----
E
W
A
G
GPLE
P
I
Q
A
I
I
P
G
G
S
S
T
P
P
-------
L
P
F
T
E
E
---
V
L
---
D
T
P
M
S
Y
E
H
L
Q
A
K
G
----------
S
M
L
G
T
G
G
V
I
L
I
P
E
R
------
V
S
M
V
D
A
M
W
N
-----
L
T
----
R
F
---
Y
A
H
E
S
C
G
K
C
T
P
C
R
E
G
V
A
G
F
M
V
N
L
F
A
K
I
G
T
--
G
-----------------
Q
G
E
E
--
K
D
V
E
N
L
E
A
L
L
P
-----
L
I
E
-----------
G
R
S
--
F
C
P
L
A
-------
D
A
A
V
W
P
V
K
G
S
L
R
H
F
K
-----------
D
Q
Y
------------
L
A
L
A
R
E
K
R
P
V
P
R
P
S
L
W
R
S
--
G
L
D
P
-------------------------------------------------------------------------------------------------------
18
Fugue
78.62
16%
-113
- C3 -
4QLA
1
HYEP_BOMMO
A:
[19-442]
L
D
L
E
E
W
W
G
P
P
E
L
K
Q
K
Q
D
T
S
I
K
P
F
E
-----------------
I
T
F
S
--
E
T
M
V
-------
K
E
L
K
E
R
--
I
K
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R
R
-
P
F
A
P
--
P
L
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F
K
Y
G
F
N
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L
D
S
W
L
K
Y
W
A
E
E
Y
P
F
---
A
E
R
Q
K
F
L
N
-
Q
------------------
Y
P
H
F
K
--------
T
N
I
Q
G
L
N
I
H
F
M
R
I
T
------
P
K
--
V
P
K
------
G
-
V
E
I
V
P
L
L
L
L
H
-
G
W
P
G
--
S
V
--
R
E
F
Y
E
A
I
P
H
L
T
A
V
S
K
D
R
N
----
F
A
L
E
I
I
A
P
S
L
P
G
Y
G
F
S
---
D
A
A
V
R
P
G
L
A
A
A
E
V
A
V
I
F
K
N
------------
L
M
A
R
L
G
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K
Q
Y
Y
V
Q
G
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D
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S
A
M
A
T
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F
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--
K
E
I
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G
F
H
S
N
M
A
--
L
T
L
S
P
A
A
T
F
L
E
F
V
G
A
L
--
F
P
S
L
I
V
E
--
P
E
L
A
N
R
L
------------------
Y
P
L
S
E
K
Y
S
-----
T
L
L
E
----
E
L
G
Y
M
H
I
Q
A
T
K
P
D
T
-------
V
G
I
G
L
T
---
D
S
---
P
A
G
L
L
A
Y
I
L
E
K
F
S
----------
T
W
T
-
N
P
D
L
R
S
K
E
D
G
G
L
S
Y
--
R
W
T
K
D
Q
L
I
D
-----
N
L
----
M
L
---
Y
W
--
S
T
K
S
I
V
T
S
M
R
L
Y
A
E
S
F
S
S
R
H
F
D
L
K
L
D
E
I
-----------------
Q
V
Q
V
--
P
T
W
V
L
Q
A
K
H
E
L
A
Y
Q
P
P
C
I
L
K
M
K
Y
------
P
K
L
V
--
N
A
S
V
I
-------
E
D
------------------------
G
G
H
------------
F
L
A
F
E
L
P
E
I
F
A
K
D
V
L
K
A
I
--
G
E
F
R
K
L
K
N---------------------------------------------------------------------------------------------------
14
Fugue
74.55
13%
-112
- C2 -
4D10
-
CSN2_HUMAN
B:
[34-447]
V
D
L
E
N
Q
Y
Y
N
S
K
A
--
L
K
E
D
D
P
K
A
A
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S
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F
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K
V
L
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L
E
G
E
K
G
E
W
G
F
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A
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--
K
Q
M
I
-------
K
I
N
-------
F
K
L
-
T
N
F
P
E
-
M
M
N
R
Y
K
Q
L
L
---
T
Y
I
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R
N
Y
S
E
K
S
I
N
---
S
I
L
D
Y
I
S
T
S
K
------------------
Q
M
D
L
L
--------
Q
E
F
Y
E
T
T
L
E
A
L
K
D
A
------
K
N
D
R
L
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F
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T
N
T
K
L
G
-
K
L
Y
L
E
------------
R
E
--
E
-
Y
G
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Q
L
H
Q
S
C
Q
----
T
Q
L
L
E
I
Y
A
L
E
I
Q
M
Y
T
A
---
Q
K
N
N
K
K
L
K
A
L
Y
E
Q
S
L
H
I
K
S
------------
A
I
P
H
P
L
I
M
G
V
I
R
E
C
G
G
K
M
H
L
R
E
-------------------------
G
E
F
E
K
A
H
T
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F
F
E
A
F
--
K
N
Y
D
E
S
G
----------
S
P
-
R
R
-
T
T
---
C
L
K
Y
L
V
L
A
N
M
L
M
K
S
---------------
G
I
N
P
F
D
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-
Q
E
A
K
-------
P
Y
K
N
D
P
---
E
I
---
L
A
M
T
N
L
V
S
A
Y
Q
N
N
----------
D
I
T
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E
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K
T
N
H
S
N
I
M
DD
P
F
I
R
E
H
I
E
E
-----
L
L
----
R
N
---
I
R
T
Q
V
L
I
K
L
I
K
P
Y
T
R
I
H
------
I
P
F
I
S
K
E
L
N
-----------------
I
D
V
A
--
D
V
E
S
L
L
V
Q
C
I
L
-----
D
N
T
I
H
G
R
------
I
D
Q
------
V
N
-------
Q
L
L
E
L
D
H
Q
K
R
G
G
A
R
Y
-----------
T
A
L
------------
D
K
W
T
N
Q
L
N
S
L
N
Q
A
V
V
S
K
L
--
A
----------------------------------------------------------------------------------------------------------
12
Fugue
70.51
10%
-152
- C4 -
3GIA
7
Y609_METJA
A:
[3-435]
--
L
K
N
K
K
----------------------------------
L
S
L
W
--
E
A
V
S
-------
M
A
V
G
V
M
--
I
G
A
S
I
-
F
S
I
----
F
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A
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I
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R
N
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A
L
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A
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---
S
Y
T
K
L
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A
K
-------------------------------------------
I
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N
------
A
G
--
P
I
A
F
I
H
K
A
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G
-
D
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A
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L
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F
A
K
G
F
A
G
Y
F
L
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L
----------------
I
N
A
P
I
---
N
T
F
N
I
A
I
T
E
I
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I
V
A
F
F
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A
L
------------
N
F
F
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S
K
A
V
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E
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F
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I
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A
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V
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V
A
I
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A
I
G
----
N
L
P
I
D
E
L
I
K
A
S
E
N
A
-------
L
A
V
A
A
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---
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F
LG
N
L
G
F
L
L
I
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----------
I
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-
A
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F
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K
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L
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A
-----------------
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I
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M
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I
Y
L
F
V
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-----
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S
H
Y
I
L
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------
D
E
V
G
G-
R
K
E
I
V
-------
I
F
S
F
I
V
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L
G
V
F
L
L
L
L
-----------
Y
Y
Q
------------
W
I
T
N
R
F
V
F
Y
G
I
I
A
T
F
I
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--
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I
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E
I
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Y
R
K
V
TK
R
T
F
S
NNMYVKS------------------------------------------------------------------------------------
2
HHSearch
68.20
11%
-145
- C4 -
3L1L
2
ADIC_ECO57
A:
[7-380]
--------------------------------------
A
H
K
V
G
L
I
--
P
V
T
L
-------
M
V
S
G
A
I
--
M
G
S
G
V
-
F
L
L
P
A
-
N
L
A
S
T
G
G
-
I
A
I
Y
G
W
L
V
T
I
I
G
A
L
G
L
S
M
V
Y
A
---
K
M
S
F
L
D
P
S
---------------------
P
G
G
S
--------
Y
A
Y
A
R
----------------------
R
C
F
G
P
F
L
-
G
Y
Q
T
N
V
L
Y
W
L
-
A
C
W
I
G
N
I
A
--
M
-
V
V
I
G
V
G
Y
L
S
Y
F
F
P
I
L
K
----
D
------------------
P
-
W
V
L
T
I
T
C
V
V
V
L
W
I
F
V
L
L
------------
N
I
V
G
P
K
M
I
T
R
V
Q
A
V
A
T
V
L
A
L
I
P
I
V
G
I
A
V
F
G
--
W
F
W
F
R
G
E
T
Y
M
A
--------
A
I
Q
S
T
L
N
V
T
L
--
W
S
F
I
G
V
E
S
A
S
V
A
A
G
V
V
K
N
P
K
R
N
-
V
P
---
I
A
T
I
G
G
V
L
I
A
A
V
C
Y
-----
V
L
S
T
----
T
A
I
M
G
M
I
P
N
A
A
L
R
V
SASP
F
G
D
A
A
R
M
A
L
---
G
D
---
T
A
G
A
I
V
S
F
C
A
A
A
G
----------
C
L
G
-
S
L
G
G
W
T
L
L
A
G
Q
T
A
K
--
A
A
A
D
D
G
L
F
P
-----
P
I
FARV
N
K
AGT
P
V
A
G
L
I
I
V
G
I
L
M
T
I
F
Q
L
S
S
I
S
P
N
A
T
K
E
F
G
L
V
S
-----------------
S
V
S
V
I
F
T
L
V
P
Y
L
Y
T
C
A
A
-----
L
L
L
L
G
H
G
------
H
F
G
K
--
A
R
P
A
Y
-------
L
A
V
T
T
I
A
F
L
Y
C
I
W
A
V
-----------
V
G
S
------------
G
A
K
E
V
M
W
S
F
V
T
L
M
V
I
T
A
M
--
Y
A
L
N
-------------------------------------------------------------------------------------------------------
17
Fugue
64.48
16%
-130
- C3 -
4IUW
2
?
A:
[4-633]
L
P
R
I
Q
D
D
L
Y
L
A
V
N
G
E
W
Q
A
K
-
T
P
I
P
P
D
K
S
V
V
S
A
D
S
N
L
T
D
D
I
R
Q
K
L
V
--
A
D
L
S
-------
T
M
T
K
-----
T
A
K
T
-
L
P
L
Q
Y
-
A
A
R
L
F
A
K
A
N
D
Q
T
R
R
Q
Q
L
G
I
E
P
V
R
D
R
I
S
F
L
M
A
L
T
T
L
D
Q
F
R
S
-
A
------------------
M
P
K
L
V
A
D
QYVLP
I
S
P
Y
V
D
A
D
M
H
D
A
E
H
N
I
L
N
L
G
G
P
D
--
T
I
L
P
D
A
A
M
Y
N
-
Q
E
D
A
E
N
A
A
D
L
-
A
A
W
S
Q
M
A
A
--
A
-
M
L
A
A
V
-
G
F
S
Q
T
D
Q
T
A
Y
----
V
E
A
A
K
R
F
D
R
R
L
A
D
Y
V
P
A
N
V
D
L
A
V
D
S
T
Y
D
N
P
L
S
W
Q
A
F
E
D
------------
A
A
G
Y
L
G
I
P
Q
A
F
A
T
Y
M
P
Q
T
P
A
K
V
N
A
V
V
P
A
Y
L
PH
L
S
K
L
L
T
P
D
N
Y
S
--
E
W
H
A
W
M
V
I
N
E
L
L
T
C
A
T
--
Y
L
S
D
D
L
R
Q
L
A
G
Q
Y
D
R
F
L
A
G
-
Q
P
-
E
A
SS
W
T
K
H
A
F
G
I
A
N
E
Y
F
D
D
-----
V
I
G
Q
----
Y
Y
G
Q
T
Y
F
G
A
D
A
K
A
D
-------
V
T
A
------------
M
V
K
Q
I
L
A
Q
Y
R
V
Q
----------
L
E
N
-
N
T
W
L
S
P
A
T
K
Q
K
A
M
R
--
K
L
A
T
M
Q
V
K
M
GYPAR
L
F
----
S
L
---
Y
D
H
L
S
V
D
V
D
D
D
L
L
T
A
I
L
K
L
S
A
Q
T
Q
A
F
W
F
K
Q
L
G
QTVDRNQWNMPGHLV
N
A
S
Y
D
P
--
L
K
N
D
I
T
F
P
A
G
I
-----
L
Q
P
P
Y
Y
S
LKWT
R
A
E
N
L
G
G
T
G
A
T
I
G
-------
H
E
I
S
H
S
F
D
N
N
-
G
A
L
Y
-----------
D
E
Y
GNLHNWWT
P
A
D
K
Q
A
F
D
Q
L
V
K
A
M
A
A
Q
F
D
G
R
D
YE
G
V
K
V
N
GTLT
V
S
E
N
M
A
D
N
A
G
M
D
V
A
L
A
L
L
GDQPD
V
K
D
L
Q
A
F
F
I
T
Y
A
R
S
W
A
T
K
M
R
P
E
R
A
K
T
V
L
R
QDVHAP
A
T
L
R
V
N
V
P
V
Q
N
F
P
A
W
Y
Q
A
F
NVQPQDGMYRQPQK
R
L
T
I
WHQ
3
HHSearch
58.77
10%
-143
* C4 *
3GIA
5
Y609_METJA
A:
[3-306]
------------------------------------
L
K
N
K
K
L
S
L
W
--
E
A
V
S
-------
M
A
V
G
V
M
--
I
G
A
S
I
-
F
S
I
F
G
V
G
A
K
I
A
G
R
-
N
L
P
E
T
F
I
L
S
G
I
Y
A
L
L
V
A
Y
S
Y
T
---
K
L
G
A
K
I
V
S
---------------------
N
A
G
P
--------
I
A
F
I
H
----------------------
K
A
I
G
D
N
I
I
T
G
A
L
S
I
L
L
W
M
-
S
Y
V
I
S
I
A
L
--
F
-
A
K
G
F
A
G
Y
F
L
P
L
I
N
A
P
I
----
N
------------------
T
-
F
N
I
A
I
T
E
I
G
I
V
A
F
F
T
A
L
------------
N
F
F
G
S
K
A
V
G
R
A
E
F
F
I
V
L
V
K
L
L
I
L
G
L
F
I
F
A
G
--
L
I
T
I
H
P
S
Y
V
I
P
DL
A
P
S
A
V
S
G
M
I
F
A
S
A
I
F
F
--
L
S
Y
M
G
F
G
V
I
T
N
A
S
E
H
I
E
N
P
K
K
N
-
V
P
---
R
A
I
F
I
S
I
L
I
V
M
F
V
Y
-----
V
G
V
A
----
I
S
A
I
G
N
L
P
I
D
E
L
I
K
A
SEN
A
--
L
A
V
A
A
K
PFL
G
N
---
L
G
F
L
L
I
S
I
G
A
L
F
S
----------
I
S
S
-
A
M
N
A
T
I
Y
G
G
A
N
V
A
Y
--
S
L
A
K
D
G
E
L
P
-----
E
F
----
F
E
---
R
K
V
W
F
K
S
T
E
G
L
Y
I
T
S
A
L
G
V
L
F
A
L
L
F
N
M
E
G
V
A
S
-----------------
I
T
S
A
--
V
F
M
V
I
Y
L
F
V
I
L
-----
S
H
Y
I
L
I
D
------
E
V
G
G
--
R
K
E
I
V
-------
I
F
S
F
I
V
V
L
G
V
F
L
L
L
L
-----------
Y
Y
Q
------------
W
I
T
N
R
F
V
F
Y
G
I
I
A
T
F
I
G
V
--
L
I
F
E
-------------------------------------------------------------------------------------------------------
15
Fugue
52.17
9%
-144
- C3 -
1H83
3
PAO_MAIZE
A:
[5-463]
-------------------------
P
R
V
I
V
V
G
----
A
G
M
S
G
I
S
A
A
--
K
R
L
S
E
A
GITD
L
L
I
L
E
A
T
DH
I
G
G
R
M
-
H
K
T
N
F
-
A
--
G
I
N
V
E
L
G
A
N
W
V
E
G
V
N
G
G
K
M
N
P
I
W
P
I
V
---
N
S
T
L
K
L
R
N
-
F
R
S
D
FDYLAQNVYKED
G
G
V
Y
D
E
D
Y
--------
V
Q
---
K
R
I
E
------------------
L
A
D
S
V
E
E
-
M
G
E
K
L
S
A
T
L
H
-----------
A
-
S
G
R
D
D
M
S
I
L
A
M
Q
R
L
N
E
----
H
Q
P
N
G
-
P
A
T
P
V
D
M
V
V
D
---
Y
Y
K
F
D
Y
E
F
A
E
P
P
R
V
T
S
L
Q
N
------------
T
V
P
L
A
T
F
S
D
F
G
D
D
V
Y
F
V
A
D
Q
R
G
Y
E
A
V
V
Y
Y
L
--
A
G
Q
Y
L
K
T
D
D
K
S
--
G
K
I
V
D
P
R
L
Q
L
N
K
V
V
R
E
--
I
K
Y
S
P
G
G
V
T
V
K
T
E
D
----
N
-
S
V
-
Y
S
---
A
D
-----
Y
V
M
V
S
A
S
-----
L
G
V
L
----
Q
S
D
L
I
Q
F
K
P
K
L
P
T
W
-------
K
V
R
A
I
Y
---
Q
F
---
D
M
A
V
Y
T
K
I
F
L
K
F
P
RKF
W
P
E
G
KGR
E
F
F
-
L
Y
A
S
S
R
R
G
Y
Y
G
V
W
Q
--
E
F
E
K
Q
Y
P
-
D
-----
A
N
----
V
L
---
L
V
T
V
T
D
E
E
S
R
R
I
E
Q
Q
S
D
E
Q
T
K
A
E
I
M
Q
V
L
R
K
M
F
-----------------
P
G
K
D
--
V
P
D
A
T
----
D
I
-----
L
V
P
R
W
W
S
------
D
R
F
Y
--
K
G
T
F
S
N
W
P
VGVN
R
Y
E
Y
D
Q
L
R
A
P
V
G
R
V
Y
F
T
G
EHTSEHYN
G
Y
V
------------
H
G
A
Y
L
S
G
I
D
S
A
E
I
L
I
N
C
A
--
Q
K
K
M
C------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
33.60
30%
-66
- C4 -
1LDF
1
GLPF_ECOLI
A:
[15-64]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
L
G
T
G
L
--
L
I
F
F
G
V
G
C
V
A
A
L
K
V
A
G
A
S
F
-
G
Q
-
W
E
---
I
S
V
I
F
G
L
G
V
A
M
A
I
Y
-----
L
T
A
G
----
V
S
G
A
H
L
N
P
A
V
T
I
A
L
-------
W
L
F
A
C
F
---
D
K
---
R
K
V
I
P
F
I
V
S
Q
V
A
G
----------
A
F
C
-
A
A
A
L
V
Y
G
L
Y
Y
N
L
F
F
--
D
F
E
Q
T
H
H
I
V
-----
R
G
----
S
V
---
E
S
V
D
L
A
G
T
F
S
T
Y
P
N
P
H
I
N
F
V
Q
A
F
A
V
E
M
V
I
T
A
I
-----------------
L
M
G
L
--
I
L
A
L
T
D
D
G
N
G
V
-----
P
R
G
P
L
A
P
------
L
L
I
G
--
L
L
I
A
V
-------
I
G
A
S
M
G
P
L
T
G
T
A
M
N
P
-----------
A
R
D
------------
F
G
P
K
V
F
A
W
L
A
G
W
G
N
V
A
F
T
--
G
G
R
D
-------------------------------------------------------------------------------------------------------
5
HHSearch
31.26
9%
-111
- C4 -
2JLN
-
?
A:
[21-183]
-----------------------------------
R
Y
A
E
R
S
V
G
P
F
--
S
L
A
A
-------
I
W
F
A
M
A
--
I
Q
V
A
I
F
I
A
A
G
Q
-
M
T
S
S
F
Q
V
W
Q
V
I
V
A
I
A
A
G
C
T
I
A
V
I
L
L
F
F
T
Q
---
S
A
A
I
R
W
-----------------------
G
I
N
F
--------
T
V
A
A
R
----------------------
M
P
F
G
I
R
G
-
S
L
I
P
I
T
L
K
A
L
-
L
S
L
F
W
F
G
F
--
Q
-
T
W
L
G
A
L
A
L
D
E
I
T
R
L
L
T
----
G
F
------------------
T
N
L
P
L
W
I
V
I
F
G
A
I
Q
V
V
T
T
-------------
F
Y
G
I
T
F
I
R
W
M
N
V
F
A
S
P
V
L
L
A
M
G
V
Y
M
V
Y
L
M
--
L
D
G
A
D
V
S
L
G
E
V
--
M
S
M
G
G
E
N
P
G
M
P
F
S
T
A
I
--
M
I
F
V
G
G
W
I
A
V
V
V
S
I
H
D
I
V
K
-
E
C
-
K
V
---
D
P
N
A
S
R
E
G
Q
T
K
A
D
A
-----
R
Y
A
T
----
A
Q
W
L
G
M
V
P
A
S
I
I
F
G
-------
F
I
G
A
A
S
---
M
V
---
L
V
G
E
W
N
P
V
I
A
I
T
E
----------
V
V
G
-
G
V
S
I
P
M
A
I
L
F
Q
V
F
V
--
L
L
A
T
W
S
T
N
P
-----
A
A
----
N
L
---
L
S
P
A
Y
T
L
C
S
T
F
P
R
V
F
T
F
K
T
G
V
I
V
S
A
V
V
G
L
L
M
M
-----------------
P
W
Q
F
--
A
G
V
L
N
T
F
L
N
L
L
-----
A
S
A
L
G
P
L
------
A
G
I
M
--
I
S
D
Y
F
-------
L
V
R
R
R
R
I
S
L
H
D
L
Y
R
T
-----------
K
G
I
------------
Y
T
Y
W
R
G
V
N
W
V
A
L
A
V
Y
A
V
A
--
L
A
V
S
-------------------------------------------------------------------------------------------------------
4
HHSearch
27.57
9%
-90
- C4 -
3DH4
1
?
A:
[52-170]
-------------------------------------
A
G
K
S
L
P
W
W
--
A
V
G
A
-------
S
L
I
A
A
N
--
I
S
A
E
Q
F
I
G
M
S
G
-
S
G
Y
S
I
G
L
A
I
A
S
-
Y
E
W
M
S
A
I
T
L
I
I
V
G
K
Y
F
L
---
P
I
F
I
E
K
G
----------------------
I
Y
T
I
--------
P
E
F
V
E
----------------------
K
R
F
N
K
K
L
-
K
T
I
L
A
V
F
W
I
S
L
Y
I
F
V
N
L
T
S
--
V
-
L
Y
L
G
G
L
A
L
E
T
I
L
G
I
---------------------------
P
L
M
Y
S
I
L
G
L
A
L
F
A
L
V
Y
S
------------
I
------
V
V
W
T
D
V
I
Q
V
F
F
L
V
L
G
G
F
M
T
T
Y
M
A
--
V
S
F
I
G
G
T
D
G
W
F
--
A
G
V
S
K
M
V
D
A
A
P
G
H
F
E
M
--
I
L
D
Q
S
N
P
Q
Y
M
N
L
P
G
I
A
V
L
I
-
G
G
-
L
W
---
V
A
N
L
Y
Y
W
G
F
N
Q
Y
I
I
-----
Q
R
T
L
----
A
A
K
S
V
S
E
A
Q
K
G
I
V
F
-------
A
A
F
L
K
L
---
I
V
---
P
F
L
V
V
L
P
G
I
A
A
Y
V
----------
I
T
S
-
D
P
Q
L
M
A
S
L
G
D
I
A
A
T
--
N
L
P
S
A
A
N
A
D
-----
K
A
----
Y
P
---
W
L
T
Q
F
L
P
V
G
V
K
G
V
V
F
A
A
L
A
A
A
I
V
S
S
L
A
S
M
L
N
S
-----------------
T
A
T
I
--
F
T
M
D
I
Y
K
E
Y
I
S
-----
P
D
S
G
D
H
K
------
L
V
N
V
--
G
R
T
A
A
-------
V
V
A
L
I
I
A
C
L
I
A
P
M
L
G
-----------
G
I
G
------------
Q
A
F
Q
Y
I
Q
E
Y
T
G
L
V
S
P
G
I
L
--
A
V
F
L
-------------------------------------------------------------------------------------------------------
13
Fugue
26.63
16%
340
- C4 -
1J5B
1
A:
[1-37]
------
D
V
A
S
D
A
K
A
A
A
E
L
V
A
A
N
A
K
A
A
A
E
L
V
A
A
N
A
K
A
A
A
E
A
V
A
R
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
HHSearch
23.74
31%
640
- C4 -
3NKU
-
DRRA_LEGPN
A:
[13-25]
-
S
L
Y
S
D
E
R
D
K
P
L
L
S
P
T
A
Q
K
K
F
E
E
Y
Q
N
K
L
A
N
L
S
K
I
I
R
E
N
E
G
N
E
V
S
P
--
W
Q
E
W
-------
E
N
G
L
R
Q
--
I
Y
K
E
M
-
I
Y
D
A
F
-
D
A
L
G
V
E
M
P
K
D
M
E
V
H
F
A
G
S
S
D
L
D
A
F
V
I
V
K
N
---
D
E
D
I
K
K
V
K
-
P
------------------
V
F
D
A
L
--------
N
N
L
C
Q
R
I
F
T
A
S
I
N
P
------
S
R
--
L
I
G
T
P
D
D
L
F
G
-
M
L
K
D
G
M
V
A
D
V
-
E
A
T
A
M
S
I
L
--
T
-
S
K
P
V
L
P
R
Y
E
L
G
E
E
L
R
D
----
K
I
K
Q
E
P
S
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
HHSearch
20.95
8%
-112
- C4 -
2WSW
-
?
A:
[87-112]
-------------------------------------
E
K
P
E
F
S
T
A
--
S
W
I
F
-------
M
M
F
A
S
C
--
T
S
A
A
V
-
L
F
W
G
S
-
I
E
I
Y
Y
Y
I
S
S
P
P
F
G
M
E
G
Y
S
A
P
A
K
E
I
G
L
A
Y
S
---
L
F
H
W
G
P
L
P
-
W
------------------
A
T
Y
S
F
--------
L
S
V
A
F
A
Y
F
F
F
V
R
K
M
------
E
V
--
I
R
P
S
S
T
L
V
P
L
-
V
G
E
K
H
V
N
G
L
F
-
G
T
V
V
D
N
F
Y
--
L
-
V
A
L
I
L
A
M
G
T
S
L
G
L
A
T
P
----
L
V
T
E
C
I
Q
Y
L
F
G
I
P
H
T
L
---
Q
L
D
A
I
I
I
S
C
W
I
L
L
N
A
I
C
V
A
------------
F
G
L
Q
K
G
V
K
I
A
S
D
V
R
T
Y
L
S
F
L
M
L
G
W
V
F
I
V
G
G
--
A
S
F
I
V
N
Y
F
T
D
S
--
V
G
T
L
L
M
Y
M
P
R
M
L
F
Y
T
D
--
P
I
G
K
G
G
F
P
Q
A
W
T
V
F
Y
W
A
W
W
-
V
I
-
Y
A
---
I
Q
M
S
I
F
L
A
R
I
S
K
G
R
-----
T
V
R
E
----
L
C
L
G
M
V
S
G
L
T
A
G
T
W
-------
L
I
W
T
I
L
---
G
G
---
N
T
L
Q
L
I
D
Q
N
I
L
N
I
----------
P
Q
L
-
I
D
Q
Y
G
V
P
R
A
I
I
E
T
W
--
A
A
L
P
L
S
T
A
T
-----
M
W
----
G
F
---
F
I
L
C
F
I
A
T
V
T
L
I
N
A
C
S
Y
T
L
A
M
S
T
C
R
S
M
K
E
G
A
D
-----------------
P
P
L
L
--
V
R
I
G
W
S
V
L
V
G
I
-----
I
G
I
I
L
L
A
------
L
G
G
L
--
K
P
I
Q
T
-------
A
I
I
A
G
G
C
P
L
F
F
V
N
I
M
-----------
V
T
L
------------
S
F
I
K
D
A
K
V
H
W
K
--------------------------------------------------------------------------------------------------------------------
9
HHSearch
20.72
18%
434
- C4 -
2KDT
-
NEC1_MOUSE
A:
[727-748]
-----------------------------
V
F
Y
N
T
K
P
Y
K
H
R
D
D
R
L
L
--
Q
A
L
M
-------
D
I
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
HHSearch
20.38
25%
703
- C1 -
1TER
1
TERT_APIME
A:
[7-18]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
I
I
I
P
H
M
C
-----
W
K
K
C
G
K
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
Fugue
17.07
20%
296
* C3 *
1LOI
1
?
?:
[1-25]
----------------------------------------------------------------------------------------------------------------------------------------------------------
M
P
L
V
D
F
F
C
E
T
C
------
S
K
--
P
W
--
L
V
G
W
W
D
-
Q
F
K
R
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------