@TOME V2.2
(Nov 2016)
Ref.
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : S39AB_HUMAN: (2015-12-10 )
MLQGHSSVFQALLGTFFTWGMTAAGAALVFVFSSGQRRILDGSLGFAAGVMLAASYWSLLAPAVEMATSSGGFGAFAFFPVAVGFTLGAAFVYLADLLMPHLGAAEDPQTTLALNFGSTLMKKKSDPEGPALLFPESELSIRIGRAGLLSDKSENGEAYQRKKAAATGLPEGPAVPVPSRGNLAQPGGSSWRRIALLILAITIHNVPEGLAVGVGFGAIEKTASATFESARNLAIGIGIQNFPEGLAVSLPLRGAGFSTWRAFWYGQLSGMVEPLAGVFGAFAVVLAEPILPYALAFAAGAMVYVVMDDIIPEAQISGNGKLASWASILGFVVMMSLDVGLG
Atome Classification :
(20 SA)
---------------------------------------------------------------------------------------------------------------.........10........20........30-.........40-------.........50...--.....60......---..70........80........90-..-.....-----.100......-----..110.......120.......130.....-----..140.......150.......160---.......-.170.......180.......190.......200----.-------.......210-----------....-.....220.......230.......240.......250.---------......260.......270.......280.......290-------.......300.......310.......320...------....330.......340--------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
---------------------------------------------------------------------------------------------------------------MLQ
G
H
S
S
V
F
Q
A
L
L
G
T
F
F
T
WGMTAA
G
A
A
L
V
F
--
V
FSSGQ
R
R
IL--------DGS
L
G
F
A
A
G
V
M
L
A
A
--
S
Y
W
S
L
L
A
P
A
V
E
M
A---TSSGGF
G
A
F
A
F
F
P
V
A
V
G
F
T
L
G
A
A
F
-
V
Y
-
L
A
D
L
L
-----
M
P
H-LGAAED-----P
Q
T
T
L
A
L
NF
G
S
T
L
M
KKKSDPEG
P
A
L
L
FPES-----
E
L
S
I
R
IGRAGLLSDKSEN
G
E
A
Y
Q
R
----
K
K
AAATG-LPEGPAVPVPSRGNLAQPGGS
S
W
R
R
I
A
L
L
I
L
A
I
-----
T
-------IHNVPE
G
L
-------------
A
VGV-G
F
G
A
I
E
K
T
A
S
A
T
F
E
SAR
N
L
A
I
G
IGIQNFPEG
L
A
V
S
LPLR---------GAGF
S
T
W
R
A
F
W
Y
G
Q
L
S
G
M
V
E
P
L
A
G
V
F
G
A
F
A
V
V
L
AE
P
I
L
P
-------
Y
A
L
A
F
AAG
A
M
V
Y
V
V
MDDIIPEAQISGNGK
L
A
S
W
------
A
S
I
L
G
F
V
V
M
M
S
LDVGLG--------------
29
Fugue
79.88
16%
-97
- C4 -
4ES8
1
?
A:
[19-320]
--------------------------------------------------------------------------------------------------------------------
E
E
L
P
D
D
L
M
N
F
K
G
T
W
E
V
S
A
D
G
S
S
G
R
F
--
F
S
K
G
A
T
D
S
Y
V
F
HLIPAKD
V
K
K
P
G
W
R
E
H
N
E
V
K
D
--
S
Y
I
K
I
D
K
Q
S
I
A
A
R
---
Y
K
T
S
T
T
A
P
Y
S
V
A
F
K
V
N
T
K
S
L
I
K
D
H
-
D
Y
-
K
I
T
F
E
-----
Q
G
Q
-
I
A
---------
S
G
I
T
V
D
Y
R
I
G
S
A
F
N
K
T
T
D
D
---------
S
F
-----
K
I
S
D
E
S
K
Y
A
S
N
V
K
I
E
G
E
E
Q
G
F
K
Q
R
E
Q
G
D
K
T
I
S
F
R
T
-
L
K
E
G
P
--------------------
M
S
L
V
L
L
S
K
-----
V
-------
E
K
K
P
Q
G
D
L
-------------
D
V
E
F
K
N
L
K
I
I
D
V
T
N
P
S
Q
L
D
K
G
V
A
---------
Y
V
G
N
K
N
V
Q
L
T
L
K
S
DDGRTNFE
G
D
E
I
S
L
F
N
S
--
R
G
E
L
L
Q
T
V
T
V
T
K
D
Q
Q
N
P
I
S
I
T
L
S
E
D
Q
A
K
-------
S
---
L
K
N
K
E
K
L
K
V
S
I
K
Q
--
K
Q
S
K
K
T
S
K
D
--------------
F
F
F
E
V
G
I
D
P
K
V
E
A
K
--------------
9
PsiBlast_CBE
60.14
31%
-91
- C6 -
3O9Z
4
?
D:
[5-124]
-----------------------------------------------------------------------------------------------------------------------------------------------------
R
F
A
L
--------
T
G
L
A
G
Y
I
A
P
R
H
L
K
A
IK
E
V
G
G
V
L
V
A
S
L
D
P
A
---
T
N
V
G
L
V
D
S
F
--
F
P
E
A
E
F
F
T
E
P
E
A
F
E
A
Y
-
L
E
D
L
R
DRGEG
V
D
Y
-
L
S
I
A
S
P
NHLHY
P
Q
I
R
M
A
L
R
L
G
A
N
A
L
S
E
K
-----
P
L
V
L
W
P
E
E
IARLK
E
L
E
A
R
T
G
R
R
V
Y
T
V
L
Q
L
R
V
H
P
S
L
L
A
----
L
K
E
R
L
G
Q
-
E
K
G
A
K
D
V
V
L
T
Y
V
T
G
R
G
K
W
Y
G
K
S
W
K
V
D
E
A
K
S
G
G
L
-----
A
-------
T
N
I
G
I
H
F
F
-------------
D
L
L
A
-
W
L
F
G
R
A
L
H
V
E
V
H
A
R
T
P
T
V
N
A
G
Y
L
E
L
E
G
A
R
V
R
W
F
L
S
I
D
P
S
---------
F
V
P
E
P
L
R
R
Q
G
K
R
T
Y
R
S
I
A
V
D
G
E
E
V
E
F
S
E
G
F
T
D
L
H
T
E
V
Y
R
-------
K
T
L
A
G
E
G
F
G
L
D
E
A
A
E
A
I
R
V
A
A
L
L
R
T
L
P
L
S
Q
P
S
P
------
E
N
R
H
P
F
L
------------------------
11
PsiBlast_CBE
60.12
31%
-88
- C6 -
3O9Z
6
?
B:
[5-124]
-----------------------------------------------------------------------------------------------------------------------------------------------------
R
F
A
L
--------
T
G
L
A
G
Y
I
A
P
R
H
L
K
A
IK
E
V
G
G
V
L
V
A
S
L
D
P
A
---
T
N
V
G
L
V
D
S
F
--
F
P
E
A
E
F
F
T
E
P
E
A
F
E
A
Y
-
L
E
D
L
R
DRGEG
V
D
Y
-
L
S
I
A
S
P
NHLHY
P
Q
I
R
M
A
L
R
L
G
A
N
A
L
S
E
K
-----
P
L
V
L
W
P
E
E
IARLK
E
L
E
A
R
T
G
R
R
V
Y
T
V
L
Q
L
R
V
H
P
S
L
L
A
----
L
K
E
R
L
G
Q
-
E
K
G
A
K
D
V
V
L
T
Y
V
T
G
R
G
K
W
Y
G
K
S
W
K
V
D
E
A
K
S
G
G
L
-----
A
-------
T
N
I
G
I
H
F
F
-------------
D
L
L
A
-
W
L
F
G
R
A
L
H
V
E
V
H
A
R
T
P
T
V
N
A
G
Y
L
E
L
E
G
A
R
V
R
W
F
L
S
I
D
P
S
---------
F
V
P
E
P
L
R
R
Q
G
K
R
T
Y
R
S
I
A
V
D
G
E
E
V
E
F
S
E
G
F
T
D
L
H
T
E
V
Y
R
-------
K
T
L
A
G
E
G
F
G
L
D
E
A
A
E
A
I
R
V
A
A
L
L
R
T
L
P
L
S
Q
P
S
P
------
E
N
R
H
P
F
L
G
-----------------------
1
PsiBlast_PDB
60.00
31%
-89
- C6 -
3O9Z
4
?
A:
[5-124]
-----------------------------------------------------------------------------------------------------------------------------------------------------
R
F
A
L
--------
T
G
L
A
G
Y
I
A
P
R
H
L
K
A
I
K
E
V
G
G
V
L
V
A
S
L
D
P
A
---
T
N
V
G
L
V
D
S
F
--
F
P
E
A
E
F
F
T
E
P
E
A
F
E
A
Y
-
L
E
D
L
R
D
R
GEG
V
D
Y
-
L
S
I
A
S
P
NHL
H
Y
P
Q
I
R
M
A
L
R
L
G
A
N
A
L
S
E
K
-----
P
L
V
L
W
P
E
E
I
A
R
L
K
E
L
E
A
R
T
G
R
R
V
Y
T
V
L
Q
L
R
V
H
P
S
L
L
A
----
L
K
E
R
L
G
Q
-
E
K
G
A
K
D
V
V
L
T
Y
V
T
G
R
G
K
W
Y
G
K
S
W
K
V
D
E
A
K
S
G
G
L
-----
A
-------
T
N
I
G
I
H
F
F
-------------
D
L
L
A
-
W
L
F
G
R
A
L
H
V
E
V
H
A
R
T
P
T
V
N
A
G
Y
L
E
L
E
G
A
R
V
R
W
F
L
S
I
D
P
S
---------
F
V
P
E
P
L
R
R
Q
G
K
R
T
Y
R
S
I
A
V
D
G
E
E
V
E
F
S
E
G
F
T
D
L
H
T
E
V
Y
R
-------
K
T
L
A
G
E
G
F
G
L
D
E
A
A
E
A
I
R
V
A
A
L
L
R
T
L
P
L
S
Q
P
S
P
------
E
N
R
H
P
F
L
G
-----------------------
7
PsiBlast_CBE
59.95
31%
-90
- C6 -
3OA0
5
?
C:
[5-124]
-----------------------------------------------------------------------------------------------------------------------------------------------------
R
F
A
L
--------
T
G
L
A
G
Y
I
A
P
R
H
L
K
A
IK
E
V
G
G
V
L
V
A
S
L
D
P
A
---
T
N
V
G
L
V
D
S
F
--
F
P
E
A
E
F
F
T
E
P
E
A
F
E
A
Y
-
L
E
D
L
R
DRGEG
V
D
Y
-
L
S
I
A
S
P
NHLHY
P
Q
I
R
M
A
L
R
L
G
A
N
A
L
S
E
K
-----
P
L
V
L
W
P
E
E
IARLK
E
L
E
A
R
T
G
R
R
V
Y
T
V
L
Q
L
R
V
H
P
S
L
L
A
----
L
K
E
R
L
G
Q
-
E
K
G
A
K
D
V
V
L
T
Y
V
T
G
R
G
K
W
Y
G
K
S
W
K
V
D
E
A
K
S
G
G
L
-----
A
-------
T
N
I
G
I
H
F
F
-------------
D
L
L
A
-
W
L
F
G
R
A
L
H
V
E
V
H
A
R
T
P
T
V
N
A
G
Y
L
E
L
E
G
A
R
V
R
W
F
L
S
I
D
P
S
---------
F
V
P
E
P
L
R
R
Q
G
K
R
T
Y
R
S
I
A
V
D
G
E
E
V
E
F
S
E
G
F
T
D
L
H
T
E
V
Y
R
-------
K
T
L
A
G
E
G
F
G
L
D
E
A
A
E
A
I
R
V
A
A
L
L
R
T
L
P
L
S
Q
P
S
P
------
E
N
R
H
P
F
L
G
-----------------------
6
PsiBlast_CBE
59.66
31%
-87
- C6 -
3OA0
5
?
D:
[5-124]
-----------------------------------------------------------------------------------------------------------------------------------------------------
R
F
A
L
--------
T
G
L
A
G
Y
I
A
P
R
H
L
K
A
IK
E
V
G
G
V
L
V
A
S
L
D
P
A
---
T
N
V
G
L
V
D
S
F
--
F
P
E
A
E
F
F
T
E
P
E
A
F
E
A
Y
-
L
E
D
L
R
DRGEG
V
D
Y
-
L
S
I
A
S
P
NHLHY
P
Q
I
R
M
A
L
R
L
G
A
N
A
L
S
E
K
-----
P
L
V
L
W
P
E
E
IARLK
E
L
E
A
R
T
G
R
R
V
Y
T
V
L
Q
L
R
V
H
P
S
L
L
A
----
L
K
E
R
L
G
Q
-
E
K
G
A
K
D
V
V
L
T
Y
V
T
G
R
G
K
W
Y
G
K
S
W
K
V
D
E
A
K
S
G
G
L
-----
A
-------
T
N
I
G
I
H
F
F
-------------
D
L
L
A
-
W
L
F
G
R
A
L
H
V
E
V
H
A
R
T
P
T
V
N
A
G
Y
L
E
L
E
G
A
R
V
R
W
F
L
S
I
D
P
S
---------
F
V
P
E
P
L
R
R
Q
G
K
R
T
Y
R
S
I
A
V
D
G
E
E
V
E
F
S
E
G
D
L
H
T
E
V
Y
R
K
T
-------
L
A
G
E
G
F
G
L
D
E
A
A
E
A
I
R
V
A
A
L
L
R
T
L
P
L
S
Q
P
S
P
E
N
------
R
H
P
F
L
--------------------------
8
PsiBlast_CBE
59.56
31%
-91
- C6 -
3OA0
5
?
B:
[5-124]
-----------------------------------------------------------------------------------------------------------------------------------------------------
R
F
A
L
--------
T
G
L
A
G
Y
I
A
P
R
H
L
K
A
IK
E
V
G
G
V
L
V
A
S
L
D
P
A
---
T
N
V
G
L
V
D
S
F
--
F
P
E
A
E
F
F
T
E
P
E
A
F
E
A
Y
-
L
E
D
L
R
DRGEG
V
D
Y
-
L
S
I
A
S
P
NHLHY
P
Q
I
R
M
A
L
R
L
G
A
N
A
L
S
E
K
-----
P
L
V
L
W
P
E
E
IARLK
E
L
E
A
R
T
G
R
R
V
Y
T
V
L
Q
L
R
V
H
P
S
L
L
A
----
L
K
E
R
L
G
Q
-
E
K
G
A
K
D
V
V
L
T
Y
V
T
G
R
G
K
W
Y
G
K
S
W
K
V
D
E
A
K
S
G
G
L
-----
A
-------
T
N
I
G
I
H
F
F
-------------
D
L
L
A
-
W
L
F
G
R
A
L
H
V
E
V
H
A
R
T
P
T
V
N
A
G
Y
L
E
L
E
G
A
R
V
R
W
F
L
S
I
D
P
S
---------
F
V
P
E
P
L
R
R
Q
G
K
R
T
Y
R
S
I
A
V
D
G
E
E
V
E
F
S
E
G
F
T
D
L
H
T
E
V
Y
R
-------
K
T
L
A
G
E
G
F
G
L
D
E
A
A
E
A
I
R
V
A
A
L
L
R
T
L
P
L
S
Q
P
S
P
------
E
N
R
H
P
F
L
G
-----------------------
10
PsiBlast_CBE
58.86
31%
-88
- C6 -
3O9Z
6
?
C:
[5-124]
-----------------------------------------------------------------------------------------------------------------------------------------------------
R
F
A
L
--------
T
G
L
A
G
Y
I
A
P
R
H
L
K
A
IK
E
V
G
G
V
L
V
A
S
L
D
P
A
---
T
N
V
G
L
V
D
S
F
--
F
P
E
A
E
F
F
T
E
P
E
A
F
E
A
Y
-
L
E
D
L
R
DRGEG
V
D
Y
-
L
S
I
A
S
P
NHLHY
P
Q
I
R
M
A
L
R
L
G
A
N
A
L
S
E
K
-----
P
L
V
L
W
P
E
E
IARLK
E
L
E
A
R
T
G
R
R
V
Y
T
V
L
Q
L
R
V
H
P
S
L
L
A
----
L
K
E
R
L
G
Q
-
E
K
G
A
K
D
V
V
L
T
Y
V
T
G
R
G
K
W
Y
G
K
S
W
K
V
D
E
A
K
S
G
G
L
-----
A
-------
T
N
I
G
I
H
F
F
-------------
D
L
L
A
-
W
L
F
G
R
A
L
H
V
E
V
H
A
R
T
P
T
V
N
A
G
Y
L
E
L
E
G
A
R
V
R
W
F
L
S
I
D
P
S
---------
F
V
P
E
P
L
R
R
Q
G
K
R
T
Y
R
S
I
A
V
D
G
E
E
V
E
F
S
E
G
F
T
D
L
H
T
E
V
Y
R
-------
K
T
L
A
G
E
G
F
G
L
D
E
A
A
E
A
I
R
V
A
A
L
L
R
T
L
P
L
S
Q
P
S
P
------
E
N
R
H
P
F
L
G
-----------------------
2
PsiBlast_PDB
58.73
31%
-91
- C6 -
3OA0
5
?
A:
[5-124]
-----------------------------------------------------------------------------------------------------------------------------------------------------
R
F
A
L
--------
T
G
L
A
G
Y
I
A
P
R
H
L
K
A
I
K
E
V
G
G
V
L
V
A
S
L
D
P
A
---
T
N
V
G
L
V
D
S
F
--
F
P
E
A
E
F
F
T
E
P
E
A
F
E
A
Y
-
L
E
D
L
R
D
R
GEG
V
D
Y
-
L
S
I
A
S
P
NHL
H
Y
P
Q
I
R
M
A
L
R
L
G
A
N
A
L
S
E
K
-----
P
L
V
L
W
P
E
E
I
A
R
L
K
E
L
E
A
R
T
G
R
R
V
Y
T
V
L
Q
L
R
V
H
P
S
L
L
A
----
L
K
E
R
L
G
Q
-
E
K
G
A
K
D
V
V
L
T
Y
V
T
G
R
G
K
W
Y
G
K
S
W
K
V
D
E
A
K
S
G
G
L
-----
A
-------
T
N
I
G
I
H
F
F
-------------
D
L
L
A
-
W
L
F
G
R
A
L
H
V
E
V
H
A
R
T
P
T
V
N
A
G
Y
L
E
L
E
G
A
R
V
R
W
F
L
S
I
D
P
S
---------
F
V
P
E
P
L
R
R
Q
G
K
R
T
Y
R
S
I
A
V
D
G
E
E
V
E
F
S
E
G
F
T
D
L
H
T
E
V
Y
R
-------
K
T
L
A
G
E
G
F
G
L
D
E
A
A
E
A
I
R
V
A
A
L
L
R
T
L
P
L
S
Q
P
S
P
------
E
N
R
H
P
F
L
G
-----------------------
23
Fugue
58.61
18%
-55
- C7 -
4IKW
13
?
A:
[3-494]
SID
K
Q
Q
I
A
A
S
VPQRGFFGHPK
G
L
F
T
L
F
F
T
E
F
W
E
R
F
S
Y
Y
G
M
R
A
I
LVYYMYYEVSKGGLGLD
E
H
L
A
L
A
I
M
S
I
Y
G
A
L
V
Y
M
S
G
I
I
G
G
W
L
A
D
RVFG
T
S
R
A
V
F
Y
G
G
L
L
I
M
A
G
H
I
A
L
A
I
P
G
G
V
A
A
L
F
V
S
M
A
L
I
V
L
G
T
G
L
L
K
P
N
V
S
S
I
V
G
D
M
Y
K
P
G
D
D
R
R
D
--------
A
G
F
S
I
F
Y
M
G
I
N
L
G
A
--
F
L
A
P
L
V
V
G
T
A
G
M
K
YN
F
H
L
G
F
G
L
A
A
V
G
M
F
L
G
L
V
V
F
V
A
T
R
K
K
-
N
L
G
L
A
G
T
Y
-----
V
P
N
P
L
T
P
A
E
K
-----
K
K
A
A
A
I
M
A
V
G
A
V
V
I
A
V
L
L
A
I
L
I
P
N
G
W
F
T
V
E
-----
T
F
I
S
L
V
G
I
L
G
I
I
I
P
I
I
Y
F
V
V
M
Y
R
S
----
P
K
T
T
A
E
E
-
R
S
R
V
I
A
Y
I
P
L
F
V
A
S
A
M
F
W
A
I
Q
E
Q
G
S
T
I
L
A
N
Y
A
D
KRTQL
D
-------
V
A
G
I
H
L
S
P
-------------
A
W
F
Q
-
S
L
N
P
L
F
I
I
I
L
A
P
V
F
A
W
M
W
V
K
L
G
K
R
Q
P
T
I
P
Q
K
F
A
L
G
L
L
F
A
---------
G
L
S
F
I
V
I
L
V
P
G
H
L
S
G
G
G
L
V
H
P
I
W
L
V
L
S
Y
F
I
V
V
L
G
E
L
C
L
S
PV
G
L
S
A
T
T
K
L
A
P
A
A
F
S
A
Q
T
M
S
L
W
F
L
S
N
A
A
A
Q
A
I
N
A
Q
L
V
R
F
YTPENE
T
A
Y
F
G
T
I
G
G
A
A
L
V
L
G
L
I
L
L
A
I
A
P
R
I
G
R
L
MKG
3
PsiBlast_PDB
47.54
36%
55
- C6 -
3MKV
-
?
A:
[99-141]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
R
G
F
T
T
V
R
D
A
G
G
A
G
Y
P
F
----
K
Q
A
V
E
S
G
-
L
V
E
G
P
R
L
F
V
S
G
R
A
-
L
S
Q
T
G
G
H
A
D
P
R
A
R
S
D
Y
M
P
P
-----
D
-------
S
P
C
G
C
C
V
R
-------------
V
G
A
L
-
G
R
V
A
D
G
V
D
E
V
R
R
A
V
R
E
E
L
Q
M
G
A
D
Q
I
K
C
X
I
M
A
S
G
G
V
A
S
P
T
---------
D
P
V
G
V
F
G
Y
S
E
D
E
I
R
A
I
V
A
E
A
Q
G
R
G
T
Y
V
L
A
H
A
Y
T
P
A
A
I
A
R
-------
A
V
R
C
G
V
R
T
I
E
H
G
N
L
I
D
D
E
T
A
R
L
V
A
E
H
G
A
Y
V
V
P
T
------
L
V
T
Y
D
A
L
A
S
E
G
E
K
Y
G
L
P
--------------
5
PsiBlast_PDB
40.22
24%
-8
- C3 -
3DWO
4
?
X:
[55-164]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
I
K
Y
N
G
D
A
Y
D
Y
----
Q
G
N
P
M
T
G
G
Y
Q
D
G
P
G
T
P
E
L
G
T
N
D
G
G
Q
A
G
F
G
A
W
L
P
T
G
F
L
V
V
P
I
-----
N
DRFAFGL
S
Q
V
V
P
M
G
M
RSTWDPNWKGRDF
A
V
D
T
-
K
I
E
T
I
G
L
T
G
S
L
S
F
K
V
N
D
N
F
S
L
G
A
G
V
I
I
Q
R
T
S
G
F
V
S
Q
N
L
D
---------
L
Y
A
S
A
A
N
S
P
G
M
G
G
I
P
F
P
A
S
N
S
S
A
L
M
R
V
K
V
D
N
T
S
P
G
F
F
A
G
-------
A
V
W
K
P
T
D
R
D
T
L
G
F
A
Y
H
A
K
I
R
N
K
L
K
G
H
Y
N
L
Y
D
H
D
------
G
G
L
T
E
G
A
I
E
G
G
T
P
G
L
A
Y
--------------
31
Fugue
35.04
19%
165
- C7 -
3PZD
-
B:
[1-36]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
K
P
T
-----
E
D
P
A
S
V
Y
E
Q
D
D
L
S
E
Q
M
A
S
L
E
G
L
M
K
----
Q
L
N
A
I
T
G
-
S
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26
Fugue
34.11
15%
130
- C7 -
1G2C
-
?
B:
[480-519]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
L
V
F
P
S
D
-----
E
F
D
A
S
I
S
Q
V
N
E
K
I
N
Q
S
L
A
F
I
R
K
S
D
----
E
L
L
H
N
V
N
-
A
G
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
28
Fugue
32.14
22%
140
* C7 *
1ZXA
-
KGP1_HUMAN
A:
[9-44]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
K
I
L
M
L
K
E
-----
E
R
I
K
E
L
E
K
R
--
L
S
E
K
E
E
E
I
Q
E
L
K
R
----
K
L
H
K
C
Q
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
32.06
30%
-20
- C5 -
3JYR
1
MALE_SALTY
A:
[167-206]
----------------------------------------------------------------------------------------------------------------
V
K
G
K
S
A
I
M
F
N
L
Q
E
P
Y
F
T
W
P
L
I
A
A
D
G
G
Y
A
F
--
K
F
E
N
G
K
Y
D
V
K
--------
D
V
G
V
D
N
A
G
A
K
A
G
L
T
--
F
L
I
D
M
I
K
N
K
N
M
S
A
---
D
T
D
Y
S
I
A
E
A
A
F
N
K
G
E
T
A
M
T
I
N
G
P
W
-
A
W
-
S
N
I
D
K
-----
S
K
V
-
N
Y
G
V
T
L
-----
L
P
T
F
K
G
K
P
S
K
P
F
V
G
V
L
S
A
G
I
N
A
A
S
P
N
K
E
L
A
-----
K
E
F
L
E
N
Y
L
L
T
D
Q
G
L
E
A
V
N
K
D
K
P
L
G
----
A
V
A
L
K
S
F
-
Q
E
Q
L
A
K
D
P
R
I
A
A
T
M
D
N
A
Q
K
G
E
I
M
P
N
I
P
Q
M
S
A
F
W
-----
Y
-------
A
V
R
T
A
V
I
N
-------------
A
A
S
G
-
R
Q
T
V
D
A
A
L
K
D
A
Q
S
R
I
T
K
---------------------------------------------------------------------------------------------------------------------------------------------------
25
Fugue
31.68
10%
85
- C7 -
2KZ9
-
VATE_YEAST
A:
[1-69]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
-----
A
S
A
-
I
T
A
L
T
P
-----
N
Q
V
N
D
E
L
N
K
M
Q
A
F
I
R
K
E
A
E
E
K
A
K
E
I
Q
L
K
A
D
-----
Q
E
Y
E
I
E
K
T
N
I
V
R
N
E
T
N
N
I
D
G
N
F
K
S
----
K
L
K
K
A
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
HHSearch
28.85
20%
-62
- C7 -
1S5L
-
PSBX_THEEB
X:
[15-29]
------------------------------------------------------------------------------------------------------------------
S
L
K
G
F
F
I
G
L
L
S
G
A
V
V
L
G
L
T
F
A
V
L
I
A
I
S
--
Q
I
D
K
V
Q
R
S
L
P
--------
F
S
D
I
I
T
S
V
R
Y
W
V
I
H
--
S
I
T
I
P
A
L
F
I
A
G
W
L
---
F
V
S
T
G
L
A
Y
D
V
F
G
T
P
R
P
D
S
Y
Y
A
Q
E
Q
-
R
S
-
I
P
L
V
T
-----
D
R
F
-
E
A
K
Q
Q
V
-----
E
T
F
L
E
Q
L
K
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
HHSearch
28.68
19%
-66
- C7 -
3WU2
-
PSBX_THEVL
X:
[4-19]
-----------------------------------------------------------------------------------------------------------------
P
S
L
K
G
F
F
I
G
L
L
S
G
A
V
V
L
G
L
T
F
A
V
L
I
A
I
S
--
Q
I
D
K
V
Q
R
G
E
R
--------
P
F
S
D
I
I
T
S
V
R
Y
W
V
I
--
H
S
I
T
I
P
A
L
F
I
A
G
W
---
L
F
V
S
T
G
L
A
Y
D
V
F
G
T
P
R
P
D
S
Y
Y
A
Q
E
-
Q
R
-
S
I
P
L
V
-----
T
D
R
-
F
E
A
K
Q
Q
-----
V
E
T
F
L
E
Q
L
K
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
HHSearch
20.88
13%
31
* C6 *
2L8S
-
A:
[10-33]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
W
V
I
L
L
S
A
F
A
G
L
L
L
-
L
M
-
L
L
I
L
A
-----
L
W
K
-
I
G
F
F
K
R
-----
P
L
K
K
K
M
E
K
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------