@TOME V2.2
(Nov 2016)
Ref.
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : S41A1_HUMAN: (2015-12-11 )
MSSKPEPKDVHQLNGTGPSASPCSSDGPGREPLAGTSEFLGPDGAGVEVVIESRANAKGVREEDALLENGSQSNESDDVSTDRGPAPPSPLKETSFSIGLQVLFPFLLAGFGTVAAGMVLDIVQHWEVFQKVTEVFILVPALLGLKGNLEMTLASRLSTAANIGHMDTPKELWRMITGNMALIQVQATVVGFLASIAAVVFGWIPDGHFSIPHAFLLCASSVATAFIASLVLGMIMIGVIIGSRKIGINPDNVATPIAASLGDLITLALLSGISWGLYLELNHWRYIYPLVCAFFVALLPVWVVLARRSPATREVLYSGWEPVIIAMAISSVGGLILDKTVSDPNFAGMAVFTPVINGVGGNLVAVQASRISTFLHMNGMPGENSEQAPRRCPSPCTTFFSPDVNSRSARVLFLLVVPGHLVFLYTISCMQGGHTTLTLIFIIFYMTAALLQVLILLYIADWMVHWMWGRGLDPDNFSIPYLTALGDLLGTGLLALSFHVLWLIGDRDTDVGD
Atome Classification :
(20 SA)
.........10........20........30........40........50........60...-.....70.........80........90........100-........110-........120......-..130--........140........150..-.....160.......170.--......----180.......190..-----.....200...-...-.210.......220.......230.......240.......---250----.......260.......270.....-----..280.....---------...290.......300.......310--.......320.......330.......340.-......350.......360.......370.......380.......390.......400.......410...------....420.......430--....-----....440...-....450......---------.460.......470.......480.....--....490....------...500.......510.--------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MSSKPEPKDVHQLNGTGPSASPCSSDGPGREPLAGTSEFLGPDGA
G
V
E
V
V
I
ESRANAKGVR
E
E
D
-
A
L
LENG-SQSNESDDVSTDRGPAPPSPLK
E
T
S
F
S
I
G
L
Q
--
V
L
F
P
F
L
L
A
G
F
--
G
T
V
A
A
G
M
V
L
D
-
I
V
Q
H
W
E
-
V
F
Q
K
---
V
T
E
V
F
I
L
V
P
-
A
L
LGLKGN
L
E
M
T
L
A
-
S
R
L
S
T
A
ANIGHMD
T
P
K
E
L
W
--
R
M
ITG
N
----
M
A
L
I
Q
V
Q
A
T
V
V
G
F
L
A
-----
S
I
A
A
V
V
F
GWIP-DGH-FS
I
P
H
A
F
L
L
C
A
S
S
V
A
T
A
F
I
A
S
L
V
L
G
M
I
M
I
G
V
IIGS
R
K
IGIN---PDN----VA
T
P
I
A
A
S
L
G
D
L
I
T
L
A
L
L
S
GIS
W
G
L
-----
Y
L
E
L-NH
W
R
Y
---------
I
Y
P
L
V
C
A
F
F
V
A
L
L
P
V
W
V
V
L
ARRSP
A
T
--
R
E
V
L
YSGW
E
P
V
I
I
A
M
A
I
S
SVG
G
L
I
L
DKTVSD-PNFAGM
A
V
F
T
P
V
I
NGVGG
N
L
V
A
V
Q
A
S
R
I
S
T
F
L
H
MNGMPGENSEQAPRRCPSP
C
T
TFFSPDVNSRS
A
R
V
L
F
L
L
------VVPG
H
L
V
F
L
Y
T
I
SCMQ---GGH
T
-----
T
L
T
L
I
F
I
I
F
Y
-
M
T
A
A
L
L
Q
V
L
I
L
L
Y
---------
I
A
D
W
M
V
H
W
M
WGRGLDPDNFS
I
P
--
Y
L
T
A
L
--
G
D
L
L
G
T
G
L
L
A
L
------
S
F
H
V
L
W
L
I
GDRDTDVGD--------
26
Fugue
84.30
19%
-109
* C7 *
4FDT
1
?
A:
[21-425]
M
Q
T
K
I
Q
K
Y
A
--------
G
T
A
M
P
Y
P
N
R
T
D
G
M
T
P
F
--
Y
I
N
H
L
G
R
H
G
A
R
F
---
P
T
S
R
---
K
A
L
D
K
V
E
-
K
V
L
V
S
A
-
Q
Q
E
N
G
L
----
T
S
E
G
M
A
L
L
S
M
I
R
R
L
S
R
L
F
D
G
Q
WG
K
L
S
K
L
G
E
T
E
Q
--
E
G
I
A
G
R
M
I
R
N
-
Y
P
Q
L
F
S
-
N
S
A
K
---
I
E
A
I
A
T
Y
V
P
R
S
I
N
S
M
D
A
F
L
S
C
M
I
R
-
H
N
P
A
L
Q
V
Q
R
S
E
G
K
Q
Y
N
H
I
L
--
R
F
F
D
L
N
----
K
S
Y
V
N
Y
K
E
K
G
-
D
W
L
P
-----
I
Y
K
A
F
V
H
K
K
I
S
---
P
-
V
P
I
M
K
K
F
L
L
N
P
E
Q
Y
L
D
K
E
A
E
E
F
V
M
A
L
F
S
V
A
A
I
L
P
D
------------------
T
S
I
P
L
N
L
E
D
L
F
T
L
D
-----
E
W
H
R
-----
Y
W
Q
T
-
Q
N
L
R
Q
---------
Y
M
S
K
S
S
A
P
V
G
K
M
L
P
V
A
I
A
-------------------
W
P
L
L
S
E
F
I
R
S
A
Q
E
V
I
S
G
K
------------------
S
D
Y
Q
A
N
F
R
F
A
H
A
E
T
V
I
P
F
V
S
L
M
G
I
E
K
T
D
V
Q
V
C
R
---
P
D
S
V
S
V
Y
W
K
----------------------------
D
Y
E
I
S
P
M
--------------
A
A
N
V
Q
W
L
F
Y
-
R
D
R
D
Q
R
I
W
V
K
I
L
L
-----------------------
N
E
E
A
A
A
L
P
--
I
S
T
A
C
--
F
P
Y
Y
S
W
E
K
T
R
I
------
F
F
N
Q
R
I
E
M
A
K
K
T
L
S
V
F
N
--------
29
Fugue
73.61
21%
-145
* C8 *
4KKI
19
TCO1_HUMAN
A:
[24-434]
--------------------
E
I
C
------------------------------
E
V
S
E
E
N
Y
I
R
L
K
-
P
L
L
N
T
M
-
I
Q
S
N
Y
N
R
G
T
S
------------------
A
V
N
--
V
V
L
S
L
K
L
V
G
I
QI
Q
T
L
M
Q
K
M
I
Q
Q
-
I
K
Y
N
V
K
-
S
R
L
S
DVS
S
G
E
L
A
L
I
I
L
-
A
L
-
G
V
C
R
N
A
E
E
N
L
I
-
Y
D
Y
H
L
I
D
K
L
-
E
N
K
F
Q
A
E
I
E
--
N
M
E
A
H
N
GTPL
T
N
Y
Y
Q
L
S
L
D
V
L
A
L
C
L
F
NGNY
S
T
A
E
V
V
N
H
F
T
P
E
N
K
N
-
Y
Y
F
G
S
Q
F
-----
S
V
D
T
G
A
M
A
V
L
A
L
T
C
V
K
K
S
L
I
N
G
Q
I
K
---
A
---
D
E
G
----
S
L
K
N
I
S
I
Y
T
K
S
L
V
E
K
I
L
S
E
K
K
E
N
G
L
--------
I
-
G
N
T
F
S
---------
T
G
E
A
M
Q
A
L
F
V
S
-----------
S
D
Y
Y
--
N
E
N
D
W
N
------
C
Q
Q
T
L
N
T
V
L
T
E
I
S
Q
G
A
F
S
N
-
P
N
A
A
A
Q
V
L
--
P
A
L
M
G
-------------
K
T
F
L
D
I
N
K
-------------
D
S
S
C
V
S
--
A
S
G
N
F
N
I
Q
S
Y
I
S
V
N
Y
------
S
V
R
I
N
E
T
Y
F
T
N
V
T
V
L
N
---
G
-
S
V
-----
F
L
S
V
M
E
K
A
Q
K
-
M
N
D
T
I
F
G
--
F
T
M
E
---------
E
R
S
W
G
P
Y
I
T
C
I
Q
G
L
C
A
N
N
N
D
R
T
--
Y
W
E
L
L
S
G
G
E
P
L
S
Q
G
A
G
S
Y
V
V
R
N
GE
N
L
E
V
R
W
S
K
Y
L
---------------
31
Fugue
71.55
15%
-85
- C5 -
4LL8
-
A:
[99-536]
------
E
R
A
A
A
Q
S
S
L
I
Q
S
H
M
Q
S
L
A
A
N
K
P
S
R
----------------------
L
S
D
E
V
K
S
M
K
Q
E
L
-
A
F
I
E
N
V
I
A
Q
A
N
K
P
K
L
V
N
V
I
R
R
E
S
G
N
P
D
L
L
E
L
L
M
D
---------------------
L
N
S
Y
T
L
E
-
V
T
E
---------------------------
G
Y
L
K
K
V
N
V
-
T
E
V
N
G
D
N
V
L
G
P
I
H
V
I
T
T
V
V
--
S
S
L
V
R
N
----
G
L
L
I
Q
S
S
K
F
I
S
K
V
L
L
-----
T
V
E
S
I
V
M
S
L
P
K
-
D
E
----------------------
T
M
L
G
G
I
F
W
L
S
N
L
S
R
L
P
A
F
A
A
N
---
Q
K
T
----
L
Y
E
A
N
G
G
D
E
K
D
-------------------
K
L
T
L
-
I
Y
L
N
D
---------
L
E
N
E
T
L
K
V
F
D
K
I
Y
S
T
W
L
V
K
F
M
K
H
A
S
A
--
H
I
E
--------
I
F
D
M
V
L
N
E
K
----
L
F
K
N
S
G
D
-
E
K
F
A
K
L
F
T
F
L
N
E
F
D
A
V
L
S
K
F
Q
V
V
D
S
M
H
T
K
I
F
N
D
T
L
K
Y
L
N
V
M
L
F
N
D
L
I
T
K
S
P
A
L
N
W
K
Y
G
Y
E
V
D
R
N
I
E
R
L
V
S
W
F
EPRIED
V
R
P
N
L
I
Q
I
I
Q
A
V
K
I
L
Q
L
KI
S
N
L
N
-----
E
F
K
L
L
F
D
F
W
Y
A
L
N
P
A
Q
I
Q
A
I
L
L
K
Y
KPANKGEAG
V
P
N
E
I
L
N
Y
L
-
A
N
V
I
K
R
E
N
L
S
L
P
G
K
M
E
I
M
L
--
S
A
Q
F
D
S
A
K
N
H
L
------
R
Y
D
T
S
A
I
T
Q
N
S
N
T
E
G
L
A
T
V
S
K
I
I
KL
28
Fugue
64.62
15%
-124
- C6 -
4OR2
9
C562_ECOLX (first)
A:
[5-372]
----
D
L
E
D
N
W
E
T
L
N
D
N
L
K
V
I
E
K
A
D
N
A
-----------------
A
Q
V
K
D
A
L
T
K
M
R
A
A
A
L
D
A
Q
K
A
T
P
P
K
L
E
D
K
-
S
----------------
P
D
S
P
E
M
K
D
F
R
H
G
F
D
--
I
L
V
G
Q
I
D
D
A
L
--
K
L
A
N
E
G
K
V
K
E
-
A
Q
A
A
A
E
-
Q
L
K
T
---
T
R
N
A
Y
I
---------------------------------------------
Q
----
K
Y
L
I
P
V
R
Y
L
-------------------------
E
-
W
S
N
I
E
S
I
I
A
I
A
F
S
C
L
G
I
L
V
T
L
F
V
T
L
I
F
V
L
-----------------
Y
----
R
D
T
P
V
V
K
S
---------------------------
S
S
R
E
L
---------
C
Y
I
I
L
A
G
I
F
L
G
Y
V
C
P
F
T
L
I
A
K
P
T
T
T
S
C
Y
L
Q
R
L
L
V
G
L
S
S
A
M
C
Y
S
A
L
V
T
K
T
N
R
I
A
R
I
L
A
R
K
-
P
R
F
M
S
----
A
W
A
Q
V
I
I
A
S
I
L
I
S
V
Q
L
T
L
V
V
T
L
I
I
M
E
P
P
M
P
I
L
S
Y
P
S
I
K
E
V
Y
L
I
C
--------
N
T
S
N
L
G
V
V
A
P
L
------
G
Y
N
G
L
L
I
M
S
C
T
Y
Y
A
F
K
---
T
R
N
V
PANFN
E
A
K
Y
I
A
F
T
M
Y
-
T
T
C
I
I
W
L
A
F
V
P
I
Y
---------
F
G
S
-------------
N
Y
K
I
I
T
--
T
C
F
A
V
--
S
L
S
V
T
V
A
L
G
C
M
------
F
T
P
K
M
Y
I
I
I
A
K
P
E
------------
2
PsiBlast_PDB
58.85
26%
-113
- C9 -
2ZY9
-
MGTE_THET8
A:
[316-459]
-----------------------------------------------------------------------------------------------------------------------
I
L
T
G
M
V
T
S
S
I
L
Q
G
F
E
S
V
L
E
A
---
V
T
A
L
A
F
Y
V
P
-
V
L
L
G
T
G
G
N
T
G
N
Q
S
A
-
T
L
I
I
R
A
L
A
T
R
D
L
D
L
R
D
--
W
--
R
R
V
F
L
K
----
E
M
G
V
G
L
L
L
G
L
T
L
S
F
L
-----
L
V
G
K
V
Y
W
-----
D
G
H
P
L
L
L
P
---
V
V
G
V
S
L
V
L
I
V
F
F
A
N
L
V
G
A
M
L
P
F
L
L
----
R
R
L
G
V
D
---
P
A
L
----
V
S
N
P
L
V
A
T
L
S
D
V
T
G
L
L
I
Y
L
S
V
A
R
L
L
-----
L
E
A
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
58.27
26%
-111
- C9 -
4U9N
4
MGTE_THET8
A:
[23-162]
-----------------------------------------------------------------------------------------------------------------------
I
L
T
G
M
V
T
S
S
I
L
Q
G
F
E
S
V
L
E
A
---
V
T
A
L
A
F
Y
V
P
-
V
L
L
G
T
G
G
N
T
G
N
Q
S
A
-
T
L
I
I
R
A
L
A
T
R
D
L
D
L
R
D
--
W
--
R
R
V
F
L
K
----
E
M
G
V
G
L
L
L
G
L
T
L
S
F
L
-----
L
V
G
K
V
Y
W
-----
D
G
H
P
L
L
L
P
---
V
V
G
V
S
L
V
L
I
V
F
F
A
N
L
V
G
A
M
L
P
F
L
L
----
R
R
L
G
V
D
---
P
A
L
----
V
S
N
P
L
V
A
T
L
S
D
V
T
G
L
L
I
Y
L
S
V
A
R
L
L
-----
L
E
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
57.92
26%
-112
- C9 -
4WIB
-
MGTE_THET8
A:
[23-162]
-----------------------------------------------------------------------------------------------------------------------
I
L
T
G
M
V
T
S
S
I
L
Q
G
F
E
S
V
L
E
A
---
V
T
A
L
A
F
Y
V
P
-
V
L
L
G
T
G
G
N
T
G
N
Q
S
A
-
T
L
I
I
R
A
L
A
T
R
D
L
D
L
R
D
--
W
--
R
R
V
F
L
K
----
E
M
G
V
G
L
L
L
G
L
T
L
S
F
L
-----
L
V
G
K
V
Y
W
-----
D
G
H
P
L
L
L
P
---
V
V
G
V
S
L
V
L
I
V
F
F
A
N
L
V
G
A
M
L
P
F
L
L
----
R
R
L
G
V
D
---
P
A
L
----
V
S
N
P
L
V
A
T
L
S
D
V
T
G
L
L
I
Y
L
S
V
A
R
L
L
-----
L
E
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
HHSearch
57.78
19%
-125
- C9 -
2ZY9
-
MGTE_THET8
A:
[300-471]
-----------------------------------------------------------------------------------------------
G
P
V
A
L
W
L
A
--
R
V
R
W
L
V
I
L
I
L
--
T
G
M
V
T
S
S
I
L
Q
-
G
F
E
--
S
-
V
L
E
A
---
V
T
A
L
A
F
Y
V
P
-
V
L
L
G
T
G
G
N
T
G
N
Q
S
A
-
T
L
I
I
R
A
L
A
T
R
D
L
D
L
R
-
D
W
R
--
R
V
F
L
K
E
----
M
G
V
G
L
L
L
G
L
T
L
S
F
L
L
-----
V
G
K
V
Y
W
D
G
H
---------
P
----
L
L
L
P
V
V
G
V
S
L
V
L
I
V
F
F
A
N
L
V
G
A
M
L
P
F
L
L
R
R
L
G
V
D
---
P
A
L
----
V
S
N
P
L
V
A
T
L
S
D
V
T
G
L
L
I
Y
L
S
V
A
R
L
L
-----
L
E
A
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
57.26
26%
-107
- C9 -
4U9L
3
MGTE_THET8
A:
[23-162]
-----------------------------------------------------------------------------------------------------------------------
I
L
T
G
M
V
T
S
S
I
L
Q
G
F
E
S
V
L
E
A
---
V
T
A
L
A
F
Y
V
P
-
V
L
L
G
T
G
G
N
T
G
N
Q
S
A
-
T
L
I
I
R
A
L
A
T
R
D
L
D
L
R
D
--
W
--
R
R
V
F
L
K
----
E
M
G
V
G
L
L
L
G
L
T
L
S
F
L
-----
L
V
G
K
V
Y
W
-----
D
G
H
P
L
L
L
P
---
V
V
G
V
S
L
V
L
I
V
F
F
A
N
L
V
G
A
M
L
P
F
L
L
----
R
R
L
G
V
D
---
P
A
L
----
V
S
N
P
L
V
A
T
L
S
D
V
T
G
L
L
I
Y
L
S
V
A
R
L
L
-----
L
E
A
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
56.75
26%
-111
- C9 -
2YVX
-
MGTE_THET8
A:
[316-459]
-----------------------------------------------------------------------------------------------------------------------
I
L
T
G
M
V
T
S
S
I
L
Q
G
F
E
S
V
L
E
A
---
V
T
A
L
A
F
Y
V
P
-
V
L
L
G
T
G
G
N
T
G
N
Q
S
A
-
T
L
I
I
R
A
L
A
T
R
D
L
D
L
R
D
--
W
--
R
R
V
F
L
K
----
E
M
G
V
G
L
L
L
G
L
T
L
S
F
L
-----
L
V
G
K
V
Y
W
-----
D
G
H
P
L
L
L
P
---
V
V
G
V
S
L
V
L
I
V
F
F
A
N
L
V
G
A
M
L
P
F
L
L
----
R
R
L
G
V
D
---
P
A
L
----
V
S
N
P
L
V
A
T
L
S
D
V
T
G
L
L
I
Y
L
S
V
A
R
L
L
-----
L
E
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
HHSearch
55.21
18%
-138
- C9 -
2ZY9
-
MGTE_THET8
A:
[302-470]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
A
L
W
L
A
R
V
R
W
L
V
I
L
I
L
T
G
M
V
T
S
S
I
L
Q
G
F
E
S
V
L
E
A
V
T
A
L
A
F
Y
V
P
V
L
L
G
T
G
G
N
T
G
N
Q
S
A
T
L
I
I
R
A
L
A
T
R
D
L
D
L
R
----
D
W
R
R
--
V
F
L
K
E
M
----------
G
V
G
L
L
L
------
G
L
T
L
S
F
L
L
V
G
K
V
Y
W
-
D
-----
G
--------
H
P
L
L
L
P
V
V
-
G
V
S
L
V
L
I
V
F
F
A
N
L
---------
V
G
A
M
L
P
F
L
L
R
R
L
G
V
D
P
A
L
V
S
N
P
--
L
V
A
T
L
--
S
D
V
T
G
L
L
I
Y
L
S
------
V
A
R
L
L
L
E
A
-----------------
8
PsiBlast_PDB
44.92
28%
-67
- C9 -
4UMV
-
?
A:
[131-200]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
I
T
L
I
V
M
M
A
I
S
W
G
L
-----
E
-
Q
F
-
N
H
P
F
G
---------
Q
L
A
F
I
A
T
T
L
V
G
L
Y
P
I
----
A
R
Q
--
A
L
--
R
L
I
K
S
G
S
Y
F
A
I
E
T
L
M
S
V
A
A
I
G
A
L
F
I
G
A
T
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
44.01
28%
-58
- C9 -
4UMW
-
?
A:
[131-200]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
I
T
L
I
V
M
M
A
I
S
W
G
L
-----
E
-
Q
F
-
N
H
P
F
G
---------
Q
L
A
F
I
A
T
T
L
V
G
L
Y
P
I
----
A
R
Q
--
A
L
--
R
L
I
K
S
G
S
Y
F
A
I
E
T
L
M
S
V
A
A
I
G
A
L
F
I
G
A
T
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
43.29
27%
43
- C9 -
2FWI
1
?
A:
[21-89]
-----------------------------
S
A
P
V
V
G
-------------
I
I
M
G
S
Q
S
D
W
E
T
M
R
H
A
D
-
A
L
L
T
E
L
-
E
I
P
H
E
T
L
I
V
S
A
D
R
T
P
D
R
L
A
D
Y
A
R
T
A
A
E
R
G
L
N
--
V
----
I
I
A
G
A
--
G
G
A
A
H
L
P
G
M
C
-
A
A
W
T
R
L
-
P
V
L
G
---
V
P
V
E
S
R
A
L
K
-
G
M
D
S
L
L
S
I
V
Q
M
P
G
G
-
V
P
V
G
T
L
A
I
G
A
S
G
A
K
N
A
A
L
L
--
A
A
S
I
L
A
----
L
Y
N
P
A
L
A
A
R
L
E
T
W
R
A
-----
L
Q
T
A
S
V
P
N
S
P
I
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
27
Fugue
37.64
30%
584
- C7 -
1PJM
-
RB_HUMAN
A:
[1-20]
------------------------------------------------------------------------------
C
G
K
R
S
A
E
G
S
N
P
P
K
P
L
K
K
L
R
G
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
37.52
25%
-38
- C9 -
1O58
-
?
A:
[101-178]
---------------------------------------------------------------------------------------------------------------------------------
V
E
R
R
K
-
V
L
K
M
---
L
G
A
E
L
V
L
T
P
-
G
E
L
G
M
K
G
A
V
E
K
A
L
E
I
S
R
E
T
G
A
H
M
L
N
Q
F
E
N
P
Y
N
V
Y
S
H
Q
F
T
T
G
P
----
E
I
L
K
Q
M
D
Y
Q
I
D
A
F
V
A
-----
G
V
G
T
G
G
T
I
S
G
V
-
G
R
V
-
L
K
G
F
F
G
N
G
V
K
I
V
A
V
E
P
A
K
S
P
V
L
S
G
G
Q
P
G
K
H
A
I
Q
G
I
G
A
G
F
V
P
---
K
I
L
----
D
R
S
V
I
D
E
V
I
T
V
E
D
E
E
A
Y
E
M
A
R
Y
L
A
K
-----
K
E
G
L
-
L
V
G
I
S
---------
S
G
A
N
V
A
A
A
L
K
V
A
Q
K
L
G
P
D
A
R
V
V
T
V
A
P
--
D
H
A
E
R
Y
L
S
I
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
37.33
40%
71
- C9 -
2I3V
1
?
A:
[208-254]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
V
G
C
N
---
L
D
S
K
G
Y
G
I
A
T
P
K
G
S
S
L
G
N
A
V
N
L
A
V
L
K
L
N
E
Q
G
L
-----
L
D
K
L
K
N
K
W
W
Y
---------
D
K
G
E
C
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
36.97
23%
-73
- C9 -
4LDS
-
?
A:
[91-201]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
S
T
N
L
A
L
L
I
I
G
R
L
I
I
G
L
A
V
G
G
S
M
S
T
V
P
V
Y
L
S
E
M
----
A
P
T
E
Y
R
G
S
L
G
S
L
N
Q
L
M
I
T
I
G
I
L
A
A
Y
L
V
N
Y
A
F
A
D
I
-
E
G
W
R
W
M
L
G
L
A
V
V
P
S
V
I
L
L
V
G
I
Y
F
M
P
E
S
P
R
W
L
L
E
N
R
N
E
E
A
A
--
R
Q
V
M
K
I
T
Y
D
D
S
E
I
D
K
E
L
K
E
M
K
E
I
N
A
I
S
E
S
T
W
-
T
V
I
K
S
P
W
L
G
R
I
L
I
V
G
C
I
F
A
I
F
Q
Q
F
I
G
I
N
A
V
I
F
Y
S
S
S
I
F
A
K
A
G
L
G
E
A
A
S
I
L
G
S
V
G
I
G
T
I
N
V
L
V
T
I
V
A
I
F
V
V
D
K
------
I
D
R
K
K
L
L
V
G
G
N
I
G
M
I
A
---
S
L
L
I
-----
M
A
I
L
I
W
T
I
G
I
-
A
S
S
A
W
I
I
I
V
C
L
S
L
---------
F
I
V
F
F
G
I
S
W
G
P
V
L
W
V
M
L
P
E
L
F
P
--
M
R
A
R
G
--
A
A
T
G
I
S
A
L
V
L
N
------
I
G
T
L
I
V
S
L
F
F
P
I
L
S
D
A
L
--------
25
Fugue
35.68
19%
63
- C9 -
4C48
-
ACRZ_ECOLI
C:
[1-46]
-----------------------------------------------------------------------------------------------------------------------------------
M
L
E
-
L
L
K
S
---
L
V
F
A
V
I
M
V
P
-
V
V
M
A
I
I
L
G
L
I
Y
G
L
G
-
E
V
F
N
I
F
S
G
V
G
K
K
D
Q
P
G
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
34.47
25%
14
- C9 -
3FCA
-
?
A:
[91-166]
---------------------------------------------------------------------------------------------------------------------------------
V
E
R
R
K
-
V
L
K
M
---
L
G
A
E
L
V
L
T
P
-
G
E
L
G
M
K
G
A
V
E
K
A
L
E
I
S
R
E
T
G
A
H
M
L
N
Q
F
E
N
P
Y
N
V
Y
S
H
Q
F
T
T
G
P
----
E
I
L
K
Q
M
D
Y
Q
I
D
A
F
V
A
-----
G
V
G
T
G
G
T
I
S
G
V
-
G
R
V
-
L
K
G
F
F
G
N
G
V
K
I
V
A
V
E
P
A
K
S
P
V
L
S
G
G
Q
P
G
K
H
A
I
Q
G
I
G
A
G
F
V
P
---
K
I
L
----
D
R
S
V
I
D
E
V
I
T
V
E
D
E
E
A
Y
E
M
A
R
Y
L
A
K
-----
K
E
G
L
-
L
V
G
I
S
---------
S
G
A
N
V
A
A
A
L
K
V
A
Q
K
L
G
P
D
A
R
V
V
T
V
A
P
--
D
H
A
E
R
Y
L
S
I
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------