@TOME V2.2
(Nov 2016)
Ref.
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : S4A10_HUMAN: (2015-12-11 )
MEIKDQGAQMEPLLPTRNDEEAVVDRGGTRSILKTHFEKEDLEGHRTLFIGVHVPLGGRKSHRRHRHRGHKHRKRDRERDSGLEDGRESPSFDTPSQRVQFILGTEDDDEEHIPHDLFTELDEICWREGEDAEWRETARWLKFEEDVEDGGERWSKPYVATLSLHSLFELRSCILNGTVLLDMHANTLEEIADMVLDQQVSSGQLNEDVRHRVHEALMKQHHHQNQKKLTNRIPIVRSFADIGKKQSEPNSMDKNAGQVVSPQSAPACVENKNDVSRENSTVDFSKGLGGQQKGHTSPCGMKQRHEKGPPHQQEREVDLHFMKKIPPGAEASNILVGELEFLDRTVVAFVRLSPAVLLQGLAEVPIPTRFLFILLGPLGKGQQYHEIGRSIATLMTDEVFHDVAYKAKDRNDLVSGIDEFLDQVTVLPPGEWDPSIRIEPPKNVPSQEKRKIPAVPNGTAAHGEAEPHGGHSGPELQRTGRIFGGLILDIKRKAPYFWSDFRDAFSLQCLASFLFLYCACMSPVITFGGLLGEATEGRISAIESLFGASMTGIAYSLFGGQPLTILGSTGPVLVFEKILFKFCKEYGLSYLSLRASIGLWTATLCIILVATDASSLVCYITRFTEEAFASLICIIFIYEALEKLFELSEAYPINMHNDLELLTQYSCNCVEPHNPSNGTLKEWRESNISASDIIWENLTVSECKSLHGEYVGRACGHDHPYVPDVLFWSVILFFSTVTLSATLKQFKTSRYFPTKVRSIVSDFAVFLTILCMVLIDYAIGIPSPKLQVPSVFKPTRDDRGWFVTPLGPNPWWTVIAAIIPALLCTILIFMDQQITAVIINRKEHKLKKGCGYHLDLLMVAVMLGVCSIMGLPWFVAATVLSITHVNSLKLESECSAPGEQPKFLGIREQRVTGLMIFILMGSSVFMTSILKFIPMPVLYGVFLYMGASSLKGIQFFDRIKLFWMPAKHQPDFIYLRHVPLRKVHLFTIIQMSCLGLLWIIKVSRAAIVFPMMVLALVFVRKLMDLLFTKRELSWLDDLMPESKKKKLEDAEKEEEQSMLAMEDEGTVQLPLEGHYRDDPSVINISDEMSKTALWRNLLITADNSKDKESSFPSKSSPS
Atome Classification :
(20 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120....-.-.-.130.......140.......150.......160.......170......-.180.......190.......200....-...210.......220........230.--......240-........250.......260.......270.......280.......290.......300.......310.......320.......330.......340-.-........350.......360..--.....370.......380...-....390.......400.......410.......420.......430.....-----..440.......450.......460.......470.......480.......490.......500.......510.......520.......530....----...540.......550......-.560.......570.......580.......590.......600.......610---.-.......620.......630.......640.......650.......660.......670.......680.......690.......700.......710.......720.......730.......740.......750.......760.......770.......780.......790.......800.......810.......820.......830.......840....-...850.......860.......870.......880.......890.......900.......910.......920....---...930.......940.......950.......960.......970.......980.......990.......1000......1010......1020......1030......1040......1050......1060......1070......1080......1090......1100......1110.....
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MEIKDQGAQMEPLLPTRND
E
E
A
V
VDRGG
T
R
S
I
L
K
T
H
F
E
K
EDLEGH
R
T
L
F
I
G
V
H
VPLGG
R
K
S
H
R
R
H
R
HRGH
K
H
R
KRDRERDSGLEDGRESPSFD
T
P
S
Q
R
V
Q
F
I
LGTEDDDEEHI
P
H
D
L
F
T
E
L
D
E
I
CW-R-E-GE
D
A
E
W
R
E
T
A
R
W
L
K
F
E
E
D
V
E
DG
G
E
RWSK
P
Y
V
A
T
L
S
L
H
S
L
F
E
L
R
S
C
ILN
G
T
-
V
L
L
DM
H
A
N
T
L
E
E
I
A
D
M
V
L
D
QQVSSGQL
N
-
E
D
V
R
H
R
V
H
E
A
L
M
K
Q
-
H
H
H
Q
N
Q
K
K
L
T
NRI--
P
I
V
R
S
F
A
-
D
-IGKKQSEPNSMDKNAGQVVSPQSAPACVENKNDVSRENS
T
V
D
FSKGLGGQQKGHTSPCGMKQRHEKGPP
H
Q
Q
E
R
E
V
D
L
H
F
M
K
KIPPGAEAS
N
I
L
V
G
E
L
E
---
F
-
L
D
R
T
V
V
A
F
V
RL
S
P
A
V
L
L
Q
G
L
A
EV--PIP
T
R
F
L
F
I
L
LGPLGKG
Q
Q
Y
H
-
E
I
G
R
S
I
A
T
L
M
T
D
E
V
F
H
D
V
A
YKAK
D
R
N
D
L
V
S
G
I
D
E
F
L
D
QVTVLPPGEWDP
S
I
R
-----IEPPKNVP
S
Q
E
KRKIPAVPNGTAAHGEAEPHGGHSG
P
E
L
Q
R
T
G
R
I
F
G
G
L
I
L
D
I
KRKAPY
F
W
S
D
F
R
D
A
F
S
L
Q
C
L
A
S
F
L
F
L
Y
C
A
C
M
S
P
V
I
T
F
G
G
LLGEATE----
G
R
I
S
A
I
E
S
L
F
GA
S
M
T
G
I
A
Y
SLF-GG
Q
P
L
T
I
LGST
G
P
V
L
V
F
E
K
I
L
F
K
F
C
K
E
Y
G
L
S
Y
L
S
L
R
ASI
G
L
W
T
A
T
L
C
I
I
L
V
AT----D-A
S
S
L
V
C
Y
I
T
R
F
T
E
E
A
F
A
S
L
I
C
I
I
F
I
Y
E
A
L
E
K
L
F
E
L
S
EAYPINMH
N
D
L
E
L
L
T
Q
YSCNCVEPHNPSNG
T
L
K
E
W
R
E
SNISA
S
D
I
I
WENL
T
V
S
E
C
K
S
L
H
G
E
Y
V
G
R
ACGHDHPYV
P
D
V
L
F
W
S
V
I
L
F
F
S
T
V
T
L
S
A
T
L
K
Q
F
KTSRY
F
P
T
K
V
R
S
I
V
S
D
F
A
V
F
L
T
I
L
C
M
V
L
I
D
Y
AIGIPSPKLQVPSVFKPTRDDR
G
W
F
VTPLGP
N
P
W
W
T
V
I
A
A
I
I
P
A
L
L
C
T
I
L
I
F
MDQQ
I
T
A
V
I
I
NR
K
E
H
K
L
-
K
KGCG
Y
H
L
D
L
L
M
V
A
V
M
L
G
V
C
S
IMG
L
P
W
F
V
A
A
T
V
L
S
I
T
H
V
N
S
L
K
LESECSAPGEQP
K
F
L
G
I
R
E
QRV
T
G
L
M
I
F
I
LMG
S
S
V
F
M
---
T
S
I
L
K
FI
P
M
P
V
L
Y
G
V
F
L
Y
MGASSLK
G
I
Q
F
F
D
R
I
K
L
F
W
MPAKHQP
D
F
I
Y
L
RHVPL
R
K
V
H
L
F
T
I
I
Q
M
S
C
L
G
L
L
W
I
IKVS
R
A
A
I
V
F
P
M
M
V
L
A
L
V
F
V
R
K
L
M
D
L
L
F
T
K
R
E
L
S
W
L
D
D
LM
P
E
S
K
K
K
K
L
E
D
A
E
K
E
E
E
Q
S
M
LAMEDEG
T
V
QLPLEGHYRDDP
S
V
I
NI
S
D
E
M
S
K
T
A
L
W
R
N
L
L
I
TADNSKDKESSFPSKSSPS
19
Fugue
91.04
31%
-42
- C3 -
1HYN
-
B3AT_HUMAN
P:
[56-348]
-------------------------------------------------------------------------------------------------------------------
K
V
Y
V
E
L
Q
E
L
V
M
D
E
-
K
-
N
Q
E
L
R
W
M
E
A
A
R
W
V
Q
L
E
E
N
L
G
E
N
G
-
A
W
G
R
P
H
L
S
H
L
T
F
W
S
L
L
E
L
R
R
V
F
T
K
G
T
-
V
L
L
D
L
Q
E
T
S
L
A
G
V
A
N
Q
L
L
D
R
F
I
F
E
D
Q
I
R
-
P
Q
D
R
E
E
L
L
R
A
L
L
L
K
-
H
S
H
A
G
E
L
E
A
L
G
G
V
--
K
P
A
V
L
T
R
-
S
-
G
D
P
S
Q
P
L
L
P
Q
H
S
S
L
E
T
Q
L
F
C
E
Q
G
---------------------------------------------
D
G
G
T
E
G
H
S
P
S
G
I
L
E
K
I
P
P
D
S
E
A
T
L
V
L
V
G
R
A
D
---
F
-
L
E
Q
P
V
L
G
F
V
R
L
Q
E
A
A
E
L
E
A
V
-
E
L
--
P
V
P
I
R
F
L
F
V
L
L
G
P
E
A
P
H
I
D
Y
T
-
Q
L
G
R
A
A
A
T
L
M
S
E
R
V
F
R
I
D
A
Y
M
A
Q
S
R
G
E
L
L
H
S
L
E
G
F
L
D
C
S
L
V
L
P
P
T
D
A
P
S
E
Q
A
-----
L
L
S
L
V
P
V
Q
R
E
L
L
R
R
R
Y
Q
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
HHSearch
90.02
29%
-43
- C3 -
1HYN
-
B3AT_HUMAN
P:
[56-348]
-------------------------------------------------------------------------------------------------------------------
K
V
Y
V
E
L
Q
E
L
V
M
-
D
E
K
-
N
Q
E
L
R
W
M
E
A
A
R
W
V
Q
L
E
E
N
L
G
E
-
N
G
A
W
G
R
P
H
L
S
H
L
T
F
W
S
L
L
E
L
R
R
V
F
T
K
G
T
-
V
L
L
D
L
Q
E
T
S
L
A
G
V
A
N
Q
L
L
D
R
F
I
F
E
D
Q
I
R
-
P
Q
D
R
E
E
L
L
R
A
L
L
L
K
-
H
S
H
A
G
E
L
E
A
L
G
G
V
--
K
-
P
A
V
L
T
-
R
-
S
G
D
P
-
S
Q
P
L
--------------
L
P
Q
H
S
S
----------------------
L
E
T
Q
L
F
C
-------
E
Q
G
D
G
G
T
E
G
H
S
P
S
G
I
L
E
K
I
P
P
D
S
E
A
T
L
V
L
V
G
R
A
D
---
F
-
L
E
Q
P
V
L
G
F
V
R
L
Q
E
A
A
E
L
E
A
-
V
E
L
--
P
V
P
I
R
F
L
F
V
L
L
G
P
E
A
P
H
I
D
Y
T
-
Q
L
G
R
A
A
A
T
L
M
S
E
R
V
F
R
I
D
A
Y
M
A
Q
S
R
G
E
L
L
H
S
L
E
G
F
L
D
C
S
L
V
L
P
P
T
D
A
P
S
E
Q
A
-----
L
L
S
L
V
P
V
Q
R
E
L
L
R
R
R
Y
Q
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
89.89
30%
-36
- C3 -
1HYN
-
B3AT_HUMAN
P:
[56-348]
-------------------------------------------------------------------------------------------------------------------
K
V
Y
V
E
L
Q
E
L
V
M
-
D
-
E
K
N
Q
E
L
R
W
M
E
A
A
R
W
V
Q
L
E
E
N
L
G
E
N
G
-
A
W
G
R
P
H
L
S
H
L
T
F
W
S
L
L
E
L
R
R
V
F
T
K
G
T
-
V
L
L
D
L
Q
E
T
S
L
A
G
V
A
N
Q
L
L
D
R
F
I
F
E
D
Q
I
R
P
Q
D
R
E
E
L
L
R
A
L
L
L
K
H
-
S
H
A
G
E
L
E
A
L
G
G
V
K
--
P
A
V
L
T
--------
R
S
G
D
P
S
-------
Q
P
L
L
P
Q
H
-----------
S
S
L
E
T
Q
L
F
C
E
Q
G
D
G
G
T
E
-
G
H
-
S
P
S
G
I
--------------------
L
E
K
I
P
P
D
S
E
A
T
L
V
L
V
G
R
A
D
---
F
-
L
E
Q
P
V
L
G
F
V
R
L
Q
E
A
A
E
L
E
A
V
-
E
L
--
P
V
P
I
R
F
L
F
V
L
L
G
P
E
A
P
H
I
D
Y
T
-
Q
L
G
R
A
A
A
T
L
M
S
E
R
V
F
R
I
D
A
Y
M
A
Q
S
R
G
E
L
L
H
S
L
E
G
F
L
D
C
S
L
V
L
P
P
T
D
A
-
P
S
E
Q
ALLSL
V
P
V
Q
R
E
L
L
R
R
R
Y
Q
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
87.67
32%
-46
- C3 -
4KY9
-
B3AT_HUMAN
A:
[7-273]
--------------------------------------------------------------------------------------------------------------------
V
Y
V
E
L
Q
E
L
V
M
-
D
-
E
K
N
Q
E
L
R
W
M
E
A
A
R
W
V
Q
L
E
E
N
L
G
E
N
G
A
-
W
G
R
P
H
L
S
H
L
T
F
W
S
L
L
E
L
R
R
V
F
T
K
G
T
-
V
L
L
D
L
Q
E
T
S
L
A
G
V
A
N
Q
L
L
D
R
F
I
F
E
D
Q
I
R
P
Q
D
R
E
E
L
L
R
A
L
L
L
K
H
-
S
H
A
G
E
L
E
A
L
G
G
V
K
--
P
A
V
L
T
--------
R
---
P
S
-------
Q
P
L
L
P
Q
H
-----------
S
S
L
E
T
Q
L
F
C
E
-------------------------------------
E
K
I
P
P
D
S
E
A
T
L
V
L
V
G
R
A
D
---
F
-
L
E
Q
P
V
L
G
F
V
R
L
Q
E
A
A
E
L
E
A
V
-
E
L
--
P
V
P
I
R
F
L
F
V
L
L
G
P
E
A
P
H
I
D
Y
T
-
Q
L
G
R
A
A
A
T
L
M
S
E
R
V
F
R
I
D
A
Y
M
A
Q
S
R
G
E
L
L
H
S
L
E
G
F
L
D
C
S
L
V
L
P
P
T
D
A
P
S
E
Q
A
-----
L
L
S
L
V
P
V
Q
R
E
L
L
R
R
R
Y
Q
S
S
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
HHSearch
59.71
21%
-48
- C3 -
1A6J
1
PTSN_ECOLI
A:
[8-157]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
Q
L
S
S
V
L
N
R
E
C
-
T
R
S
R
V
H
C
Q
S
K
K
R
A
L
E
I
I
S
E
L
A
A
K
Q
L
S
L
P
----
P
Q
V
V
F
E
A
I
L
T
R
-
E
-----
K
M
-----------
G
S
T
-
G
-
I
G
N
G
-----------------------------------------------------------------------------
I
A
I
P
H
---------
G
K
L
E
E--
D
-
T
L
R
A
V
G
V
F
V
Q
L
E
T
P
I
A
F
D
A
I
D
N
----
Q
P
V
D
L
L
F
A
L
L
V
P
A
D
Q
T
K
T
H
L
-
H
T
L
S
L
V
A
K
R
L
A
D
K
T
I
C
R
R
L
R
A
A
Q
S
D
E
E
L
Y
Q
I
I
T
D
T
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
HHSearch
57.06
21%
-59
- C3 -
3URR
3
?
A:
[2-152]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
M
N
R
L
A
K
I
L
P
L
E
N
-
V
V
I
G
L
S
V
T
S
K
K
R
V
F
E
Q
A
G
L
I
F
E
N
Q
N
G
I
A
----
R
S
T
V
T
D
N
L
F
A
R
-
E
R
L
----------------
G
S
T
-
G
-
L
G
E
G
-----------------------------------------------------------------------------
V
A
I
P
H
---------
G
R
I
K
---
G
-
L
K
H
P
L
A
A
F
V
R
L
A
E
P
I
P
F
E
A
P
D
G
----
Q
P
V
S
L
L
I
F
L
L
V
P
E
Q
A
T
Q
A
H
L
-
E
I
L
S
E
I
A
Q
L
L
S
D
R
D
T
R
E
R
L
H
T
E
P
D
R
D
E
L
H
R
L
L
T
Q
W
Q
P
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
HHSearch
53.72
17%
-56
- C3 -
2A0J
-
?
A:
[4-147]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
G
E
I
L
P
L
S
H
-
I
V
L
D
M
E
V
G
S
K
K
R
L
F
E
E
A
G
L
L
L
E
R
E
S
S
L
S
----
H
A
D
V
F
E
C
L
F
A
R
-
E
-----
K
L
-----------
G
S
T
-
G
-
L
G
Q
G
-----------------------------------------------------------------------------
V
A
I
P
H
---------
G
R
H
A
---
G
-
V
K
Q
A
T
G
A
F
I
R
T
R
E
P
V
G
F
D
A
P
D
G
----
K
P
V
S
L
I
F
I
L
L
V
P
E
N
A
T
G
E
H
L
-
E
V
L
S
K
L
A
G
K
F
S
Q
K
S
I
R
E
S
L
M
T
V
S
S
A
E
E
V
R
A
I
L
T
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
HHSearch
53.37
15%
-51
- C3 -
1A3A
-
PTM3C_ECOLI
A:
[4-147]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
F
K
L
G
A
E
N
-
I
F
L
G
R
K
A
A
T
K
E
E
A
I
R
F
A
G
E
Q
L
V
K
G
G
Y
V
E
-----
P
E
Y
V
Q
A
M
L
D
R
-
E
-----
K
L
-----------
T
P
T
-
Y
-
L
G
E
S
-----------------------------------------------------------------------------
I
A
V
P
H
---------
G
T
V
E
AKD
R
-
V
L
K
T
G
V
V
F
C
Q
Y
P
E
G
V
R
F
G
E
E
E
----
D
D
I
A
R
L
V
I
G
I
A
A
R
N
N
---
E
H
I
-
Q
V
I
T
S
L
T
N
A
L
D
D
E
S
V
I
E
R
L
A
H
T
T
S
V
D
E
V
L
E
L
L
A
G
R
K
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
HHSearch
53.07
17%
-48
- C3 -
3OXP
-
?
A:
[4-150]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
L
K
T
L
L
T
S
D
V
-
I
Q
V
V
S
Q
A
K
D
W
R
D
A
I
A
I
S
C
Q
P
L
I
D
N
G
A
V
E
-----
A
R
Y
V
E
A
I
Y
R
S
-
H
E
----
A
I
-----------
G
P
Y
Y
V
-
V
G
P
G
-----------------------------------------------------------------------------
I
A
M
P
H
---------
A
R
P
E
D--
G
-
V
N
R
L
S
L
A
L
T
V
I
T
E
G
V
T
F
N
A
E
G
N
----
D
P
V
K
L
L
I
V
L
A
A
T
D
S
--
N
S
H
I
-
E
A
I
S
Q
L
A
Q
L
F
D
T
A
S
D
V
Q
A
L
L
N
A
K
T
P
Q
D
I
L
S
V
I
A
R
Y
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
HHSearch
52.44
13%
-130
- C3 -
3QE7
2
URAA_ECOLI
A:
[9-341]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
E
R
P
P
-
L
L
Q
T
I
P
L
S
L
Q
H
L
F
A
M
F
G
---
A
T
V
L
V
P
V
L
F
H
----------------
I
N
P
A
T
V
L
L
F
N
G
I
G
T
L
L
Y
L
F
I
C
K
G
K
I
P
A
Y
L
G
S
S
F
A
F
I
S
P
---
V
L
L
L
L
-
P
L
G
Y
E
V
A
---
L
G
G
F
I
M
C
G
V
L
F
C
L
V
S
F
I
V
K
K
A
G
-
T
G
W
L
D
V
L
F
P
P
A
A
M
G
A
I
V
A
V
I
G
L
E
L
A
G
V
A
A
G
M
A
G
L
-
L
---
P
A
E
G
-------------------------------------------------------------------
Q
T
P
D
S
K
T
I
I
I
S
I
T
T
L
A
V
T
V
L
G
S
V
L
F
R
-
G
--------
F
L
A
I
I
P
I
L
I
G
V
L
V
G
Y
A
L
S
F
A
M
G
I
V
D
T
T
-
P
I
I
--------
N
A
H
W
F
A
L
P
T
L
Y
T
P
R
F
E
-
W
F
A
I
L
T
I
L
P
A
A
L
V
V
I
A
E
H
V
G
H
L
V
V
T
A
N
I
V
K
K
D
L
L
R
D
P
G
L
H
R
S
M
F
A
N
G
L
S
T
V
I
S
G
F
F
G
S
T
P
N
T
T
Y
G
E
N
I
G
V
M
A
I
T
----------
R
V
--------
Y
S
T
W
V
I
G
G
A
A
I
F
A
I
L
L
S
C
V
G
K
L
A
A
A
I
Q
M
I
P
L
P
V
M
G
G
V
S
L
L
L
Y
G
V
I
G
A
S
G
I
R
V
L
I
E
S
K
V
D
Y
N
K
A
Q
N
L
I
L
T
S
V
I
L
I
I
G
V
S
G
A
K
V
N
I
G
A
A
E
L
K
G
M
A
L
A
T
I
V
G
I
G
L
S
L
I
F
K
L
I
S
--------------------------------------------------------------------------------------------------------
16
HHSearch
51.63
13%
-52
- C3 -
3BJV
-
?
A:
[3-150]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
A
Q
A
F
K
E
N
H
S
I
R
L
G
L
T
A
K
D
W
K
E
A
V
K
L
S
V
T
P
L
I
E
S
G
A
V
K
-----
P
E
Y
Y
N
A
I
I
E
S
T
E
-----
S
Y
-----------
G
P
Y
-
Y
I
L
M
P
G
-----------------------------------------------------------------------------
M
A
M
P
H
---------
A
R
P
E
A--
G
-
V
Q
R
D
A
F
S
L
V
T
L
T
E
P
V
T
F
T
D
--
G
----
K
E
V
Q
V
L
L
A
L
A
A
T
S
S
--
K
I
H
T
S
V
A
I
P
Q
I
I
A
L
F
E
L
D
H
S
I
E
R
L
V
N
C
K
T
P
E
E
V
L
A
M
V
E
E
S
K
S
S
P
Y
L
E
G
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
HHSearch
47.73
15%
29
- C3 -
2OQT
-
?
A:
[7-151]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
I
D
N
N
S
-
I
R
L
G
L
S
A
D
T
W
Q
E
A
V
R
L
A
V
Q
P
L
I
D
S
K
A
V
T
-----
S
A
Y
Y
D
A
I
I
A
S
T
E
-----
K
Y
-----------
G
P
Y
Y
V
-
L
M
P
G
-----------------------------------------------------------------------------
M
A
M
P
H
---------
A
E
A
-L--
G
-
V
N
R
N
A
F
A
L
I
T
L
T
K
P
V
T
F
S
D
--
G
----
K
E
V
S
V
L
L
T
L
A
A
T
D
P
--
S
I
H
T
T
V
A
I
P
Q
I
V
A
L
F
E
L
D
N
A
I
E
R
L
V
A
C
Q
S
P
K
E
V
L
E
M
V
E
E
S
K
D
S
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
HHSearch
47.69
13%
-47
- C3 -
2OQ3
-
PTMA_ECOLI
A:
[2-146]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
L
S
D
Y
F
P
E
S
S
-
I
S
V
I
H
S
A
K
D
W
Q
E
A
I
D
F
S
M
V
S
L
L
D
K
N
Y
I
-----
S
E
N
Y
I
Q
A
I
K
D
S
-
T
-----
I
N
N
G
---------
P
Y
Y
-
I
-
L
A
P
G
-----------------------------------------------------------------------------
V
A
M
P
H
---------
A
R
P
E
---
C
G
A
L
K
T
G
M
S
L
T
L
L
E
Q
G
V
Y
F
P
G
N
D
-----
E
P
I
K
L
L
I
G
L
S
A
A
D
A
--
D
S
H
I
-
G
A
I
Q
A
L
S
E
L
L
C
E
E
E
I
L
E
Q
L
L
T
A
S
S
E
K
Q
L
A
D
I
I
S
R
G
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
HHSearch
42.63
15%
-1
- C3 -
3T43
-
?
A:
[48-141]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
I
P
H
---------
T
D
S
K
---
Y
-
V
R
Q
N
A
I
S
V
G
I
L
A
E
P
V
N
F
E
D
A
G
G
E
PD
P
V
P
V
R
V
V
F
M
L
A
L
G
N
W
--
F
D
I
T
-
N
V
L
W
W
I
M
D
V
I
Q
D
A
D
F
M
Q
Q
L
L
V
M
N
D
D
-
E
I
Y
Q
S
I
Y
T
R
I
S
E
A
A
G
M
A
G
I
H
F
R
R
H
Y
V
-----
R
H
L
P
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
HHSearch
32.60
12%
-4
- C3 -
3QE7
2
URAA_ECOLI
A:
[226-353]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
A
I
L
T
I
L
P
A
A
L
V
V
I
A
E
H
V
G
H
L
V
V
T
A
N
I
V
K
KDLL
R
D
P
G
L
H
R
S
M
F
A
N
G
L
S
T
V
I
S
G
F
F
-
G
S
T
P
N
T
T
Y
G
--
E
N
I
G
V
----
M
----
A
I
T
R
V
---
Y
S
T
-
W
V
I
G
G
A
A
I
F
A
I
L
L
S
C
V
----
G
K
L
A
A
A
I
Q
M
I
P
L
P
V
M
G
G
V
S
L
L
L
Y
G
V
I
G
A
S
G
I
R
V
L
I
E
S
K
V
D
Y
N
K
A
Q
N
L
I
L
T
S
V
I
L
I
I
G
V
S
G
A
K
V
N
I
G
A
A
E
L
K
G
M
A
L
A
T
I
V
G
I
G
L
S
L
I
F
K
L
I
S
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
27
Fugue
31.62
12%
237
- C3 -
3NO7
-
?
A:
[10-69]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
K
M
T
V
T
V
G
-
E
E
R
R
A
R
L
R
T
A
Y
T
L
T
-
H
L
Q
E
G
H
R
T
F
S
G
F
I
A
A
A
L
D
A
E
V
Q
-
R
-
L
E
Q
R
Y
N
E
G
R
R
F
E
N
A
E
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
28
Fugue
29.28
17%
472
- C3 -
1KIL
-
CPLX1_RAT
E:
[9-49]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
K
E
E
E
R
Q
E
A
L
R
Q
A
E
E
E
R
K
A
K
Y
A
K
M
E
A
E
R
E
V
M
R
Q
G
I
R
D
K
Y
G
I
-------------------------------------------------
3
PsiBlast_PDB
27.87
60%
297
- C3 -
1BZK
1
A:
[1-41]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
Y
P
Y
Y
L
S
D
I
T
D
A
F
S
P
Q
V
L
A
A
V
I
F
I
Y
F
A
A
L
S
P
A
I
T
F
G
G
L
L
G
E
K
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
Fugue
27.69
59%
288
- C3 -
1BZK
1
?
?:
[1-42]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
Y
P
Y
Y
L
S
D
I
T
D
A
F
S
P
Q
V
L
A
A
V
I
F
I
Y
F
A
A
L
S
P
A
I
T
F
G
G
L
L
G
E
K
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26
Fugue
22.51
21%
1247
- C1 -
3UL0
-
NCBP1_MOUSE
C:
[3-25]
--------------------------------------------------------
M
S
R
R
R
H
S
D
E
N
D
G
G
Q
P
H
K
R
R
K
T
S
D
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------