@TOME V2.2
(Nov 2016)
Ref.
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : S4A4_HUMAN: (2015-12-11 )
MEDEAVLDRGASFLKHVCDEEEVEGHHTIYIGVHVPKSYRRRRRHKRKTGHKEKKEKERISENYSDKSDIENADESSSSILKPLISPAAERIRFILGEEDDSPAPPQLFTELDELLAVDGQEMEWKETARWIKFEEKVEQGGERWSKPHVATLSLHSLFELRTCMEKGSIMLDREASSLPQLVEMIVDHQIETGLLKPELKDKVTYTLLRKHRHQTKKSNLRSLADIGKTVSSASRMFTNPDNGSPAMTHRNLTSSSLNDISDKPEKDQLKNKFMKKLPRDAEASNVLVGEVDFLDTPFIAFVRLQQAVMLGALTEVPVPTRFLFILLGPKGKAKSYHEIGRAIATLMSDEVFHDIAYKAKDRHDLIAGIDEFLDEVIVLPPGEWDPAIRIEPPKSLPSSDKRKNMYSGGENVQMNGDTPHDGGHGGGGHGDCEELQRTGRFCGGLIKDIKRKAPFFASDFYDALNIQALSAILFIYLATVTNAITFGGLLGDATDNMQGVLESFLGTAVSGAIFCLFAGQPLTILSSTGPVLVFERLLFNFSKDNNFDYLEFRLWIGLWSAFLCLILVATDASFLVQYFTRFTEEGFSSLISFIFIYDAFKKMIKLADYYPINSNFKVGYNTLFSCTCVPPDPANISISNDTTLAPEYLPTMSSTDMYHNTTFDWAFLSKKECSKYGGNLVGNNCNFVPDITLMSFILFLGTYTSSMALKKFKTSPYFPTTARKLISDFAIILSILIFCVIDALVGVDTPKLIVPSEFKPTSPNRGWFVPPFGENPWWVCLAAAIPALLVTILIFMDQQITAVIVNRKEHKLKKGAGYHLDLFWVAILMVICSLMALPWYVAATVISIAHIDSLKMETETSAPGEQPKFLGVREQRVTGTLVFILTGLSVFMAPILKFIPMPVLYGVFLYMGVASLNGVQFMDRLKLLLMPLKHQPDFIYLRHVPLRRVHLFTFLQVLCLALLWILKSTVAAIIFPVMILALVAVRKGMDYLFSQHDLSFLDDVIPEKDKKKKEDEKKKKKKKGSLDSDNDDSDCPYSEKVPSIKIPMDIMEQQPFLSDSKPSDRERSPTFLERHTSC
Atome Classification :
(21 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.....-.-.-120.......130....------...140.......150.--......160.......-170.......180.......190.....--..200.......210........220.-----...-..---.230.......240......-.250.......260.......270.......280.......290.---.-.....300.......310.....--..320.......330......-.340.......350.......360.......370.......380.......390.......400.......410.......420.......430.......440.......450.......460.......470.......480.......490....----...500.......510......-.520.......530.......540.......550.......560.......570---........580.......590.......600.......610.......620.......630.......640.......650.......660.......670.......680.......690.......700.......710.......720.......730.-----.....--------------.740......-.750--.......760.......770.......780.......790.......800.......810.-......820.......830.......840.......850.......860.......870.......880.......890---.......900.......910.......920.......930.......940.......950.......960.......970.......980.......990.......1000......1010......1020......1030......1040......1050......1060......1070......
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
ME
D
E
A
V
L
D
R
G
A
S
F
L
K
H
VC
D
E
E
EVEGH
H
T
I
Y
I
G
V
HV
P
K
S
Y
R
R
R
R
R
H
KRKTG
H
K
E
K
K
E
K
E
R
I
SENYSDKSDIENADE
S
S
S
S
I
L
K
P
L
I
S
P
A
A
E
R
I
R
F
I
LGEEDDSPAP
P
Q
L
F
T
E
L
D
E
L
L
A-V-D-GQE
M
E
W
K
E
T
A
R
W
I
K
F
E
E
------
K
V
E
QG
G
E
RWSKP
H
V
A
T
L
--
S
L
H
S
L
F
E
L
R
T
C
M
EKG
S
-
I
M
L
D
R
E
A
S
S
L
P
Q
L
V
E
M
I
V
DHQIETGLLK--P
E
L
K
D
K
V
T
Y
T
L
L
R
K
-
H
R
H
Q
T
K
K
S
N
L
R
S
-----
L
A
D
-
I
G
---
K
T
V
S
S
A
S
RMFTNPDNGSPA
M
-
T
HRNLTSSSLNDISDKP
E
K
D
Q
L
K
N
K
F
M
K
KLPRDAEASN
V
L
V
GEVD---F-LD
T
P
F
I
A
F
V
R
L
Q
Q
A
V
M
L
G
A
LTEV--PVP
T
R
F
L
F
I
L
LGPKGK
A
K
S
Y
H
-
E
I
G
R
A
I
A
T
L
M
S
D
E
V
F
H
D
I
A
YKAK
D
R
H
D
L
I
A
G
I
D
E
F
L
D
E
V
I
V
LPPGEWDP
A
I
RIEPPKSLPS
S
D
K
RKNMYSGGE
N
V
Q
MNGDTPHDGGHGGGGHG
D
C
E
E
L
Q
R
T
G
R
F
C
G
G
L
I
K
D
I
K
R
KAPF
F
A
S
D
F
Y
D
A
L
N
I
Q
A
L
S
A
I
L
F
I
Y
L
A
T
V
T
N
A
I
T
FGGLLGDAT
D
----
N
M
Q
G
V
L
E
S
F
L
G
T
A
V
S
G
A
I
F
C
L
F-AGQ
P
L
T
I
LSST
G
P
V
L
V
F
E
R
L
L
F
NFSKDNNF
D
Y
L
E
F
R
L
W
I
G
L
W
S
A
F
L
C
L
I
L
VAT----
D
A
S
F
L
V
Q
Y
F
T
R
F
T
E
E
G
F
S
S
L
I
S
F
I
F
I
Y
D
A
F
K
K
M
I
K
L
ADYYPINSN
F
K
V
G
Y
N
T
L
F
S
C
TCVPPDPA
N
I
S
ISNDTTLA
P
E
YLPTMSSTDMYHNTTF
D
W
AFL
S
K
K
E
C
S
K
YGGNLVGNNCNFV
P
D
I
T
L
M
S
F
I
L
F
L
GTY
T
S
S
M
A
L
K
K
FKTSPYF
P
T
T
A
R
K
L
I
S
D
F
A
I
I
-----
L
S
I
L
I
--------------
F
C
V
I
D
A
L
VGV-DTP
K
--
L
IVPSEFKPTSPNR
G
W
FVPPFGENP
W
W
V
C
L
A
A
A
I
P
A
L
L
V
T
I
L
I
F
MDQQ
I
T
A
V
I
VNR
K
E
HKL-KKGAGY
H
L
D
L
F
W
V
A
I
L
M
V
I
C
S
L
M
A
L
P
W
Y
V
A
A
T
V
I
S
I
A
H
ID
S
L
K
METETSAPGEQP
K
F
L
G
V
R
EQRV
T
G
T
L
V
F
I
L
T
G
L
S
V
F
---
M
A
P
I
L
K
FI
P
M
P
V
L
Y
G
V
F
L
Y
M
G
V
A
SLN
G
V
Q
F
M
D
R
L
K
L
L
L
MPLKHQP
D
F
I
Y
L
RHVP
L
R
R
V
H
L
F
T
F
L
Q
V
L
C
L
A
L
L
W
I
L
K
S
T
V
A
A
I
I
F
P
V
M
I
L
A
L
V
A
V
R
K
G
M
D
Y
L
F
SQH
D
L
S
F
L
D
D
VIPEKDKK
K
K
E
D
E
K
K
K
K
K
KKGSLDSDNDDSDCPYSEKVPSIKI
P
M
D
I
M
EQQPFLSDSKPSDRERS
P
T
F
L
E
RHTSC
18
Fugue
94.57
34%
-43
- C2 -
1HYN
-
B3AT_HUMAN
P:
[56-348]
----------------------------------------------------------------------------------------------------------
K
V
Y
V
E
L
Q
E
L
V
M
D
E
-
K
-
N
Q
E
L
R
W
M
E
A
A
R
W
V
Q
L
E
E
------
N
L
G
E
N
G
-
A
W
G
R
P
H
L
S
H
L
--
T
F
W
S
L
L
E
L
R
R
V
F
T
K
G
T
-
V
L
L
D
L
Q
E
T
S
L
A
G
V
A
N
Q
L
L
D
R
F
I
F
E
D
Q
I
R
--
P
Q
D
R
E
E
L
L
R
A
L
L
L
K
-
H
S
H
---
A
G
E
L
E
A
-----
L
G
G
-
V
K
---
P
A
V
L
T
R
S
G
D
P
S
Q
P
L
L
P
Q
H
S
S
-
L
E
T
Q
L
F
C
E
Q
----
G
D
G
G
T
E
G
H
S
P
S
G
I
L
E
K
I
P
P
D
S
E
A
T
L
V
L
V
G
R
A
D
---
F
-
L
E
Q
P
V
L
G
F
V
R
L
Q
E
A
A
E
L
E
A
V
-
E
L
--
P
V
P
I
R
F
L
F
V
L
L
G
P
E
A
P
H
I
D
Y
T
-
Q
L
G
R
A
A
A
T
L
M
S
E
R
V
F
R
I
D
A
Y
M
A
Q
S
R
G
E
L
L
H
S
L
E
G
F
L
D
C
S
L
V
L
P
P
T
D
A
P
S
E
Q
A
L
L
S
L
V
P
V
Q
R
E
L
L
R
R
R
Y
Q
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
93.57
36%
-48
- C2 -
1HYN
-
B3AT_HUMAN
P:
[56-323]
----------------------------------------------------------------------------------------------------------
K
V
Y
V
E
L
Q
E
L
V
M
-
D
-
E
K
N
Q
E
L
R
W
M
E
A
A
R
W
V
Q
L
E
E
------
N
L
G
E
N
G
-
A
W
G
R
P
H
L
S
H
L
--
T
F
W
S
L
L
E
L
R
R
V
F
T
K
G
T
-
V
L
L
D
L
Q
E
T
S
L
A
G
V
A
N
Q
L
L
D
R
F
I
F
E
D
Q
I
R
--
P
Q
D
R
E
E
L
L
R
A
L
L
L
K
-
H
S
H
---
A
G
E
L
E
A
-----
L
G
G
-
V
K
---
P
A
V
L
T
R
S
G
-----
D
P
S
Q
P
L
L
P
Q
H
S
S
L
E
T
Q
L
F
C
E
Q
G
D
G
G
T
E
G
H
S
P
S
G
I
L
E
K
I
P
P
D
S
E
A
T
L
V
L
V
G
R
A
D
---
F
-
L
E
Q
P
V
L
G
F
V
R
L
Q
E
A
A
E
L
E
A
V
-
E
L
--
P
V
P
I
R
F
L
F
V
L
L
G
P
E
A
P
H
I
D
Y
T
-
Q
L
G
R
A
A
A
T
L
M
S
E
R
V
F
R
I
D
A
Y
M
A
Q
S
R
G
E
L
L
H
S
L
E
G
F
L
D
C
S
L
V
L
P
P
T
D
A
P
S
E
Q
A
L
L
S
L
V
P
V
Q
R
E
L
L
R
R
R
Y
Q
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
93.36
36%
-56
- C2 -
4KY9
-
B3AT_HUMAN
A:
[7-273]
-----------------------------------------------------------------------------------------------------------
V
Y
V
E
L
Q
E
L
V
M
-
D
-
E
K
N
Q
E
L
R
W
M
E
A
A
R
W
V
Q
L
E
E
------
N
L
G
E
N
G
A
-
W
G
R
P
H
L
S
H
L
--
T
F
W
S
L
L
E
L
R
R
V
F
T
K
G
T
-
V
L
L
D
L
Q
E
T
S
L
A
G
V
A
N
Q
L
L
D
R
F
I
F
E
D
Q
I
R
--
P
Q
D
R
E
E
L
L
R
A
L
L
L
K
-
H
S
H
---
A
G
E
L
E
A
-----
L
G
G
-
V
K
---
P
A
V
L
T
R
--------
P
S
Q
P
L
L
P
Q
H
S
S
L
E
T
Q
L
F
C
E
---------------
E
K
I
P
P
D
S
E
A
T
L
V
L
V
G
R
A
D
---
F
-
L
E
Q
P
V
L
G
F
V
R
L
Q
E
A
A
E
L
E
A
V
-
E
L
--
P
V
P
I
R
F
L
F
V
L
L
G
P
E
A
P
H
I
D
Y
T
-
Q
L
G
R
A
A
A
T
L
M
S
E
R
V
F
R
I
D
A
Y
M
A
Q
S
R
G
E
L
L
H
S
L
E
G
F
L
D
C
S
L
V
L
P
P
T
D
A
P
S
E
Q
A
L
L
S
L
V
P
V
Q
R
E
L
L
R
R
R
Y
Q
S
S
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
HHSearch
91.51
31%
-44
- C2 -
1HYN
-
B3AT_HUMAN
P:
[56-348]
----------------------------------------------------------------------------------------------------------
K
V
Y
V
E
L
Q
E
L
V
M
-
D
E
K
-
N
Q
E
L
R
W
M
E
A
A
R
W
V
Q
L
E
E
------
N
L
G
E
-
N
G
A
W
G
R
P
H
L
S
H
L
--
T
F
W
S
L
L
E
L
R
R
V
F
T
K
G
T
-
V
L
L
D
L
Q
E
T
S
L
A
G
V
A
N
Q
L
L
D
R
F
I
F
E
D
Q
I
R
--
P
Q
D
R
E
E
L
L
R
A
L
L
L
K
-
H
S
H
A
G
E
L
E
A
L
G
G
VKPAV
L
T
R
-
S
G
---
D
P
S
-
Q
P
L
L
---------
P
---
Q
H
S
S
L
E
T
Q
L
F
C
E
Q
G
D
G
G
T
E
G
H
S
P
S
G
I
L
E
K
I
P
P
D
S
E
A
T
L
V
L
V
G
R
A
D
---
F
-
L
E
Q
P
V
L
G
F
V
R
L
Q
E
A
A
E
L
E
A
-
V
E
L
--
P
V
P
I
R
F
L
F
V
L
L
G
P
E
A
P
H
I
D
Y
T
-
Q
L
G
R
A
A
A
T
L
M
S
E
R
V
F
R
I
D
A
Y
M
A
Q
S
R
G
E
L
L
H
S
L
E
G
F
L
D
C
S
L
V
L
P
P
T
D
A
P
S
E
Q
A
L
L
S
L
V
P
V
Q
R
E
L
L
R
R
R
Y
Q
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
HHSearch
66.28
23%
-64
- C2 -
3URR
3
?
A:
[2-152]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
M
N
R
L
A
K
I
L
P
L
E
N
-
V
V
I
G
L
S
V
T
S
K
K
R
V
F
E
Q
A
G
L
I
F
E
N
Q
N
G
I
A
-----
R
S
T
V
T
D
N
L
F
A
R
-
E
R
L
G
-------------
S
T
G
-
L
G
---
E
G
V
----------------------------------------------
A
I
P
H
---------
G
R
I
K
---
G
-
L
K
H
P
L
A
A
F
V
R
L
A
E
P
I
P
F
E
A
P
D
G
----
Q
P
V
S
L
L
I
F
L
L
V
P
E
Q
A
T
Q
A
H
L
-
E
I
L
S
E
I
A
Q
L
L
S
D
R
D
T
R
E
R
L
H
T
E
P
D
R
D
E
L
H
R
L
L
T
Q
W
Q
P
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
HHSearch
65.44
21%
-75
- C2 -
2A0J
-
?
A:
[4-147]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
G
E
I
L
P
L
S
H
-
I
V
L
D
M
E
V
G
S
K
K
R
L
F
E
E
A
G
L
L
L
E
R
E
S
S
L
S
-----
H
A
D
V
F
E
C
L
F
A
R
-
E
K
L
G
-------------
S
T
G
-
L
G
---
Q
G
V
----------------------------------------------
A
I
P
H
---------
G
R
H
A
---
G
-
V
K
Q
A
T
G
A
F
I
R
T
R
E
P
V
G
F
D
A
P
D
G
----
K
P
V
S
L
I
F
I
L
L
V
P
E
N
A
T
G
E
H
L
-
E
V
L
S
K
L
A
G
K
F
S
Q
K
S
I
R
E
S
L
M
T
V
S
S
A
E
E
V
R
A
I
L
T
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
HHSearch
61.48
15%
-120
- C2 -
3QE7
2
URAA_ECOLI
A:
[9-341]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
E
R
P
P
-
L
L
Q
T
I
P
L
S
L
Q
H
L
F
A
M
F
G
A
T
---
V
L
V
P
V
L
F
H
----------------
I
N
P
A
T
V
L
L
F
N
G
I
G
T
L
L
Y
L
F
I
C
K
G
K
I
P
A
Y
L
G
S
S
F
A
F
I
S
---
P
V
L
L
L
L
-
P
L
G
---
Y
E
V
A
L
G
G
F
I
M
C
G
V
L
F
C
L
V
S
F
I
V
K
K
A
G
T
G
W
L
D
V
L
F
P
P
A
A
M
G
A
I
V
A
V
I
G
L
E
L
A
G
V
A
A
G
M
A
-
G
L
L
---
P
A
E
--------------------
G
------------------------------------------------------
Q
T
P
D
S
K
T
I
I
I
S
I
T
T
L
A
V
T
V
L
G
S
V
L
F
R
G
-----
F
----
L
A
I
I
P
I
L
-----
I
G
V
L
V
--------------
G
Y
A
L
S
F
A
M
G
I
V
D
T
T
P
----
I
I
--------
N
A
H
W
F
A
L
P
T
L
Y
T
P
R
F
E
-
W
F
A
I
L
T
I
L
P
A
A
L
V
V
I
A
E
H
V
G
H
L
V
V
T
A
N
I
V
K
K
D
L
L
R
D
P
G
L
H
R
S
M
F
A
N
G
L
S
T
V
I
S
G
F
F
G
S
T
P
N
T
T
Y
G
E
N
I
G
V
M
A
I
T
----------
R
V
Y
--------
S
T
W
V
I
G
G
A
A
I
F
A
I
L
L
S
C
V
G
K
L
A
A
A
I
Q
M
I
P
L
P
V
M
G
G
V
S
L
L
L
Y
G
V
I
G
A
S
G
I
R
V
L
I
E
S
K
V
D
Y
N
K
A
Q
N
L
I
L
T
S
V
I
L
I
I
G
V
S
G
A
K
V
N
I
G
A
A
E
L
K
G
M
A
L
A
T
I
V
G
I
G
L
S
L
I
F
K
L
I
S
--------------------------------------------------------------------------------------------------
11
HHSearch
61.11
11%
-62
- C2 -
1A3A
-
PTM3C_ECOLI
A:
[4-146]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
F
K
L
G
A
E
N
-
I
F
L
G
R
K
A
A
T
K
E
E
A
I
R
F
A
G
E
Q
L
V
K
G
G
Y
V
E
------
P
E
Y
V
Q
A
M
L
D
R
-
E
K
L
T
-------------
P
T
Y
-
L
G
---
E
S
I
----------------------------------------------
A
V
P
H
---------
G
T
V
E
AKD
R
-
V
L
K
T
G
V
V
F
C
Q
Y
P
E
G
V
R
F
G
E
E
E
----
D
D
I
A
R
L
V
I
G
I
A
A
R
N
---
N
E
H
I
-
Q
V
I
T
S
L
T
N
A
L
D
D
E
S
V
I
E
R
L
A
H
T
T
S
V
D
E
V
L
E
L
L
A
G
R
K
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
HHSearch
60.88
15%
-79
- C2 -
3BJV
-
?
A:
[2-149]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
L
A
Q
A
F
K
E
N
H
S
I
R
L
G
L
T
A
K
D
W
K
E
A
V
K
L
S
V
T
P
L
I
E
S
G
A
V
------
K
P
E
Y
Y
N
A
I
I
E
S
T
E
S
Y
G
-------------
P
Y
Y
I
L
M
---
P
G
M
----------------------------------------------
A
M
P
H
---------
A
R
P
E
A--
G
-
V
Q
R
D
A
F
S
L
V
T
L
T
E
P
V
T
F
T
D
--
G
----
K
E
V
Q
V
L
L
A
L
A
A
T
S
S
--
K
I
H
T
S
V
A
I
P
Q
I
I
A
L
F
E
L
D
H
S
I
E
R
L
V
N
C
K
T
P
E
E
V
L
A
M
V
E
E
S
K
S
S
P
Y
L
E
G
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
HHSearch
60.80
18%
-63
- C2 -
1A6J
1
PTSN_ECOLI
A:
[8-157]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
Q
L
S
S
V
L
N
R
E
C
-
T
R
S
R
V
H
C
Q
S
K
K
R
A
L
E
I
I
S
E
L
A
A
K
Q
L
S
L
P
-----
P
Q
V
V
F
E
A
I
L
T
R
-
E
K
M
G
-------------
S
T
G
-
I
G
---
N
G
I
----------------------------------------------
A
I
P
H
---------
G
K
L
E
E--
D
-
T
L
R
A
V
G
V
F
V
Q
L
E
T
P
I
A
F
D
A
I
D
N
----
Q
P
V
D
L
L
F
A
L
L
V
P
A
D
Q
T
K
T
H
L
-
H
T
L
S
L
V
A
K
R
L
A
D
K
T
I
C
R
R
L
R
A
A
Q
S
D
E
E
L
Y
Q
I
I
T
D
T
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
HHSearch
57.77
16%
-72
- C2 -
3OXP
-
?
A:
[4-150]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
L
K
T
L
L
T
S
D
V
-
I
Q
V
V
S
Q
A
K
D
W
R
D
A
I
A
I
S
C
Q
P
L
I
D
N
G
A
V
------
E
A
R
Y
V
E
A
I
Y
R
S
H
E
A
I
G
-------------
P
Y
Y
V
V
G
---
P
G
I
----------------------------------------------
A
M
P
H
---------
A
R
P
E
D--
G
-
V
N
R
L
S
L
A
L
T
V
I
T
E
G
V
T
F
N
A
E
G
N
----
D
P
V
K
L
L
I
V
L
A
A
T
D
S
--
N
S
H
I
-
E
A
I
S
Q
L
A
Q
L
F
D
T
A
S
D
V
Q
A
L
L
N
A
K
T
P
Q
D
I
L
S
V
I
A
R
Y
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
HHSearch
56.09
15%
-73
- C2 -
3T43
-
?
A:
[3-141]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
Q
N
D
I
I
K
A
L
A
S
P
L
I
N
D
G
M
V
------
V
S
D
F
A
D
H
V
I
T
R
-
E
Q
N
A
-------------
P
T
G
-
L
P
VEP
V
G
V
----------------------------------------------
A
I
P
H
---------
T
D
S
K
---
Y
-
V
R
Q
N
A
I
S
V
G
I
L
A
E
P
V
N
F
E
D
A
G
G
E
PD
P
V
P
V
R
V
V
F
M
L
A
L
G
N
W
--
F
D
I
T
-
N
V
L
W
W
I
M
D
V
I
Q
D
A
D
F
M
Q
Q
L
L
V
M
N
D
D
-
E
I
Y
Q
S
I
Y
T
R
I
S
E
A
A
G
M
A
G
I
H
F
R
R
H
Y
V
R
H
L
P
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
HHSearch
54.43
13%
-63
- C2 -
2OQ3
-
PTMA_ECOLI
A:
[2-146]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
L
S
D
Y
F
P
E
S
S
-
I
S
V
I
H
S
A
K
D
W
Q
E
A
I
D
F
S
M
V
S
L
L
D
K
N
Y
I
------
S
E
N
Y
I
Q
A
I
K
D
S
-
T
I
N
N
G
P
-----------
Y
Y
I
-
L
A
---
P
G
V
----------------------------------------------
A
M
P
H
---------
A
R
P
E
---
C
G
A
L
K
T
G
M
S
L
T
L
L
E
Q
G
V
Y
F
P
G
N
-----
D
E
P
I
K
L
L
I
G
L
S
A
A
D
A
--
D
S
H
I
-
G
A
I
Q
A
L
S
E
L
L
C
E
E
E
I
L
E
Q
L
L
T
A
S
S
E
K
Q
L
A
D
I
I
S
R
G
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
HHSearch
49.71
13%
7
- C2 -
2OQT
-
?
A:
[7-151]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
I
D
N
N
S
-
I
R
L
G
L
S
A
D
T
W
Q
E
A
V
R
L
A
V
Q
P
L
I
D
S
K
A
V
------
T
S
A
Y
Y
D
A
I
I
A
S
T
E
K
Y
G
-------------
P
Y
Y
V
L
M
---
P
G
M
----------------------------------------------
A
M
P
H
---------
A
E
A
-L--
G
-
V
N
R
N
A
F
A
L
I
T
L
T
K
P
V
T
F
S
D
--
G
----
K
E
V
S
V
L
L
T
L
A
A
T
D
P
--
S
I
H
T
T
V
A
I
P
Q
I
V
A
L
F
E
L
D
N
A
I
E
R
L
V
A
C
Q
S
P
K
E
V
L
E
M
V
E
E
S
K
D
S
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
Fugue
41.70
11%
28
- C2 -
3WUQ
-
A:
[3-265]
--------------------------------------------------------------
T
V
D
Q
V
E
E
L
R
R
D
L
R
I
K
S
Q
E
L
E
V
K
N
A
A
A
N
D
K
L
K
K
M
V
K
D
Q
Q
E
A
E
K
K
K
V
M
S
Q
E
I
Q
E
Q
L
H
-
K
-
Q
-
Q
E
V
I
A
D
K
Q
M
S
V
K
E
D
L
D
K
V
E
P
A
V
I
E
A
Q
N
A
V
K
S
I
K
K
Q
H
L
V
E
V
R
S
M
A
N
P
P
A
A
V
K
L
A
L
E
S
I
C
-
L
L
L
G
E
S
T
T
D
W
K
Q
I
R
S
I
I
M
R
E
N
F
I
P
T
I
V
N
FS
A
E
E
I
S
D
A
I
R
E
K
M
K
K
-
N
Y
M
S
N
P
S
Y
N
Y
E
I
-----
V
N
R
-
A
S
---
L
A
C
G
P
M
V
K
W
A
I
A
Q
L
N
Y
A
D
M
L
-
K
R
V
E
P
L
R
N
E
L
Q
K
L
E
D
D
A
K
D
N
Q
Q
K
A
N
E
V
E
Q
M
I
R
D
L
E
A
S
I
A
R
Y
K
E
E
Y
---
A
-
V
L
I
S
E
A
Q
A
I
K
A
D
L
A
A
V
E
A
K
V
N
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
38.53
25%
9
- C1 -
2NYG
1
YOKD_BACSU
A:
[2-100]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
K
K
I
V
E
S
T
T
F
P
R
T
K
Q
S
I
T
E
D
L
K
A
L
G
L
K
K
G
M
T
V
L
V
H
S
S
LSSIGWVNGG
A
V
A
V
I
Q
A
L
I
D
V
-
V
T
E
E
G
T
I
V
M
P
S
Q
S
V
E
L
S
D
P
K
E
W
G
N
P
P
V
P
E
E
-
W
W
D
I
I
R
E
S
M
P
A
Y
N
S
N
Y
T
P
T
T
R
G
M
G
Q
I
V
E
L
F
R
S
Y
P
E
V
-
K
R
S
N
H
P
N
Y
S
F
V
A
W
G
K
H
K
N
K
I
L
N
Q
H
P
L
E
F
G
L
G
E
Q
S
P
L
G
K
L
Y
I
R
E
S
Y
V
L
L
L
G
A
D
F
D
S
S
T
C
F
H
L
A
E
Y
R
I
P
Y
Q
K
I
I
N
R
G
A
P
I
I
---
V
E
G
K
R
V
W
K
E
Y
K
E
L
E
F
R
E
E
L
F
Q
E
V
G
Q
A
F
E
A
E
H
N
M
K
V
G
K
V
G
S
A
N
C
R
L
F
S
L
T
E
A
V
D
F
A
E
K
W
F
I
N
N
D
S
K
N
I
------------------------------------------------------------------------------------------------------------------------
25
Fugue
33.82
12%
371
- C2 -
1DEB
-
APC_HUMAN
A:
[1-54]
----------------------------------
A
A
A
S
Y
D
Q
L
L
K
Q
V
E
A
L
K
M
E
N
S
N
L
R
Q
E
L
E
D
N
S
N
H
L
T
K
L
E
T
E
A
S
N
M
K
E
V
L
K
Q
L
Q
G
S
I
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26
Fugue
33.22
24%
485
- C2 -
1HF9
-
B:
[1-41]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
L
K
K
H
H
E
N
E
I
S
H
H
A
K
E
I
E
R
L
Q
K
E
I
E
R
H
K
Q
S
I
K
K
L
K
Q
S
E
D
D
D
----------------------------------------------
27
Fugue
33.15
24%
485
- C2 -
1HF9
-
ATIF1_BOVIN
A:
[1-41]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
L
K
K
H
H
E
N
E
I
S
H
H
A
K
E
I
E
R
L
Q
K
E
I
E
R
H
K
Q
S
I
K
K
L
K
Q
S
E
D
D
D
----------------------------------------------
17
HHSearch
31.11
17%
44
* C2 *
3QE7
2
URAA_ECOLI
A:
[226-341]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
A
I
L
T
I
L
P
A
A
L
V
V
I
A
E
H
V
G
H
L
V
V
T
A
N
I
V
K
KDLL
R
D
P
G
L
H
R
S
M
F
A
N
G
L
S
T
V
I
S
G
F
F
-
G
S
T
P
N
T
T
Y
G
E
N
I
--
G
V
--------
M
A
I
T
R
V
---
Y
-
S
T
W
V
I
G
G
A
A
I
F
A
I
L
L
S
C
V
G
---
K
L
A
A
A
I
Q
M
I
P
L
P
V
M
G
G
V
S
L
L
L
Y
G
V
I
G
A
S
G
I
R
V
L
I
E
S
K
V
D
Y
N
K
A
Q
N
L
I
L
T
S
V
I
L
I
I
G
V
S
G
A
K
V
N
I
G
A
A
E
L
K
G
M
A
L
A
T
I
V
G
I
G
L
S
L
I
F
K
L
I
S
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
Fugue
22.43
50%
307
- C2 -
1BZK
1
?
?:
[1-42]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
Y
P
Y
Y
L
S
D
I
T
D
A
F
S
P
Q
V
L
A
A
V
I
F
I
Y
F
A
A
L
S
P
A
I
T
F
G
G
L
L
G
E
K
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------