@TOME V2.2
(Nov 2016)
Ref.
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : S52A1_HUMAN: (2015-12-11 )
MAAPTLGRLVLTHLLVALFGMGSWAAVNGIWVELPVVVKDLPEGWSLPSYLSVVVALGNLGLLVVTLWRQLAPGKGEQVPIQVVQVLSVVGTALLAPLWHHVAPVAGQLHSVAFLTLALVLAMACCTSNVTFLPFLSHLPPPFLRSFFLGQGLSALLPCVLALVQGVGRLECPPAPTNGTSGPPLDFPERFPASTFFWALTALLVTSAAAFRGLLLLLPSLPSVTTGGSGPELQLGSPGAEEEEKEEEEALPLQEPPSQAAGTIPGPDPEAHQLFSAHGAFLLGLMAFTSAVTNGVLPSVQSFSCLPYGRLAYHLAVVLGSAANPLACFLAMGVLCRSLAGLVGLSLLGMLFGAYLMALAILSPCPPLVGTTAGVVLVVLSWVLCLCVFSYVKVAASSLLHGGGRPALLAAGVAIQVGSLLGAGAMFPPTSIYHVFQSRKDCVDPCGP
Atome Classification :
(16 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140........150.......160.......170.......180.......--190.......200.......210.......220.......230.......240.......250....-------------...260.......270.......280.......290....--...300.......310.......320-...--------......330------......-------..340.....-----..350.......360.......370.......380........390.......400.......410.......420....---...430.......440......-----------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MAA
P
T
L
G
R
L
V
L
T
H
L
L
V
A
L
FGMGS
W
A
A
V
N
G
I
W
V
E
L
P
V
V
V
K
DLPEGWS
L
P
S
Y
L
S
V
V
V
A
LGN
L
G
L
L
V
V
T
L
W
R
Q
LAPGKGEQ
V
P
I
Q
V
V
Q
V
L
S
V
V
G
T
A
L
L
A
P
L
W
H
H
V
A
P
V
A
G
Q
L
H
S
V
A
F
L
T
L
A
L
V
L
A
M
A
C
CTSNV
T
F
L
P
F
L
S
HLP
P
-
P
F
L
R
S
F
F
L
GQ
G
L
S
A
L
L
P
C
V
L
A
L
V
Q
G
VGRLECPPAPTNGTSGPPLD
F
P
E--RFP
A
S
T
F
F
W
A
L
T
A
L
L
V
T
S
A
A
A
F
R
G
L
L
L
LLPSLPSVTTGGSGPELQLGSPGA
E
E
E
E
K
E
E
E
EALPLQEP-------------PSQAAGTIPGP
D
P
E
A
H
Q
L
F
S
A
H
G
A
F
L
L
G
L
M
A
F
T
S
A
V
TNGV--LPSVQSFSCLP
Y
G
R
L
A
Y
H
L
A
V
V
LG---SAA--------
N
P
L
A
C
F
L
A
-------
M
G
V
L
C
R
-------
S
L
A
G
L
V
G
L
S
L
-----
L
G
M
L
F
G
A
Y
L
M
A
L
A
I
LSPCPPLVG
T
T
A
G
V
V
L
V
V
L
S
-
W
V
L
C
L
C
V
F
S
Y
V
K
V
A
A
S
S
L
LHGGG
R
P
A
L
L
AA
G
V
A
I
Q
V
G
S
L
LGAGAM---FP
P
T
S
I
Y
H
V
F
Q
SRKDCVDPCGP-----------------------
16
Fugue
84.92
17%
-97
- C3 -
4BIJ
-
TERL_BPT7
A:
[1-476]
M
S
T
Q
S
N
R
N
A
L
V
V
A
Q
L
K
G
D
F
V
----
A
F
L
F
V
L
W
K
A
L
-----
N
L
P
V
P
T
K
C
Q
I
D
M
A
K
V
L
A
N
G
D
N
K
K
F
I
L
Q
A
F
R
G
I
G
---------
K
S
F
I
T
C
A
F
V
V
W
S
L
W
R
D
P
Q
L
K
I
L
I
V
S
A
S
K
E
R
A
D
A
N
S
I
F
I
K
N
I
I
-------
D
L
L
P
F
L
S
E
L
K
P
R
P
G
Q
R
D
S
V
I
S
F
D
V
G
P
A
N
P
D
H
S
P
S
V
K
S
V
G
-----
I
T
G
Q
L
T
G
S
R
A
D
I
I
I
A
D
DV
E
I
P
S
N
S
A
T
M
G
A
R
E
K
L
W
T
L
V
Q
E
F
A
A
L
L
K
P
L
P
S
S
R
V
I
Y
L
G
T
P
Q
T
E
M
T
L
Y
K
E
L
E
D
N
R
G
Y
T
T
I
I
W
P
A
L
Y
P
R
-------------
T
R
E
E
N
L
Y
Y
S
Q
R
L
A
M
L
R
A
E
Y
D
E
N
P
E
A
L
A
G
T
P
T
D
P
V
R
F
D
R
D
D
--
L
R
E
R
E
----
L
E
Y
G
K
A
G
F
T
L
Q
F
M
L
N
P
NL
S
D
A
EKYPLRLR
D
A
I
V
A
A
L
D
L
E
KAM
H
Y
Q
W
L
P
N
R
QNIIE
D
L
P
N
V
G
L
K
G
D
D
L
HTYHD
C
S
N
N
S
G
Q
Y
Q
Q
K
I
L
V
I
D
P
S
G
R
G
K
D
E
T
G
Y
A
V
L
Y
T
L
N
G
Y
I
Y
L
M
E
A
G
G
F
R
D
G
Y
S
D
K
T
L
E
L
L
A
K
K
A
K
Q
W
G
V
Q
T
V
V
Y
E
S
N
F
G
D
G
M
F
GK
V
F
S
P
I
L
L
K
H
H
N
C
A
M
E
E
I
R
A
R
G
M
K
EM
R
I
C
D
T
L
E
P
V
M
Q
T
H
R
LVIRDEV
13
Fugue
38.20
16%
67
- C6 -
1Q0V
-
VPS27_YEAST
A:
[249-329]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
D
R
D
Y
S
T
P
E
D
E
E
E
L
I
R
K
A
I
E
L
S
L
K
E
S
RNSA
S
S
E
P
I
VPVV
E
S
K
N
E
V
K
R
Q
E
I
E
E
E
E
D
P
D
L
K
A
A
I
Q
E
S
L
R
E
A
E
E
A
K
L
R
S
E
R
Q
--
K
A
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
Fugue
36.49
10%
167
- C6 -
2K88
-
VATG_YEAST
A:
[1-60]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
V
S
Q
K
N
G
I
A
T
L
L
Q
A
E
K
E
A
H
E
I
V
S
K
A
R
K
Y
R
Q
D
K
L
K
Q
A
-------------
K
T
D
A
A
K
E
I
D
S
Y
K
I
Q
K
D
K
E
L
K
E
F
E
C
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
Fugue
35.41
16%
25
- C6 -
1YX4
-
A:
[1-112]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
M
L
G
L
G
A
S
D
F
E
F
G
V
D
P
S
A
D
P
E
L
A
L
A
L
R
V
S
M
E
E
Q
R
Q
R
Q
E
E
E
A
-------------
R
R
A
A
A
A
S
A
A
E
A
G
I
A
T
T
G
T
E
D
S
D
D
A
L
L
K
M
T
I
S
Q
Q
E
F
G
R
T
G
L
PD
L
S
S
M
T
E
E
E
Q
I
A
Y
A
M
Q
M
S
L
Q
G
A
E
F
G
---
Q
A
E
--------
S
A
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
Fugue
33.86
21%
238
* C6 *
2L5G
-
GPS2_HUMAN
A:
[53-90]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
K
E
M
E
E
R
M
S
L
E
E
T
K
E
Q
-------------
I
L
K
L
E
E
K
L
L
A
L
Q
E
E
K
H
Q
L
F
L
Q
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
Fugue
33.80
16%
207
- C6 -
2KWY
-
A:
[1-43]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
D
N
A
G
G
V
G
E
L
E
K
K
A
E
A
G
V
Q
G
E
L
-------------
A
E
I
K
K
I
A
E
K
K
K
D
D
V
V
K
I
L
I
E
T
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
Fugue
33.67
33%
306
- C6 -
1Q0W
-
A:
[1-24]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
P
E
D
E
E
E
L
I
R
K
A
I
E
L
S
L
K
E
S
-------------
R
N
S
A
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
Fugue
32.89
5%
196
- C6 -
2KHK
-
ATPF_ECOLI
A:
[1-53]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
A
A
I
E
K
R
Q
K
E
I
A
D
G
L
A
S
A
E
R
A
H
K
D
L
D
L
A
K
A
S
A
T
D
Q
L
K
K
A
-------------
K
A
E
A
Q
V
I
I
E
Q
A
N
K
R
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
Fugue
32.15
18%
74
- C6 -
2YZT
-
?
A:
[2-67]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
R
R
Y
R
V
V
V
E
R
D
E
E
G
Y
F
V
A
H
V
P
E
L
H
A
H
T
Q
A
Q
S
F
E
E
L
L
R
R
L
Q
E
A
I
A
V
S
L
E
E
E
R
A
E
V
V
G
L
E
-------------
G
A
L
E
I
E
A
A
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
HHSearch
27.16
30%
366
- C2 -
1SLU
-
?
A:
[106-125]
-----------------------
M
L
R
Y
N
S
---
K
L
P
I
V
V
-
Y
T
P
D
N
V
D
V
K
Y
R
V
W
K
A
E
E
K
I
D
N
A
V
V
R
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
HHSearch
26.53
67%
221
- C4 -
2MDW
-
?
A:
[2-27]
----------------------------------------
L
P
P
G
W
E
K
R
C
F
Y
F
N
A
S
R
A
R
I
I
L
T
T
H
G
K
R
A
R
Q
G
L
F
E
R
A
R
P
S
D
A
S
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
HHSearch
24.98
21%
494
- C6 -
3BYB
-
VKT1_PSETT
A:
[45-58]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
N
F
I
T
K
E
E
C
E
S
T
C
A
------------------------
9
HHSearch
23.24
29%
550
- C6 -
1IRH
-
A:
[46-59]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
N
F
T
S
K
Q
E
C
L
R
A
C
K
K
-----------------------
3
HHSearch
22.77
57%
1715
- C1 -
3LE4
-
DGCR8_HUMAN
A:
[302-308]
---------------------------------------
P
L
P
D
G
W
I
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
HHSearch
20.07
53%
729
- C5 -
2RFE
-
ERRFI_HUMAN
E:
[18-32]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
N
G
V
--
M
P
P
T
Q
S
F
A
P
D
P
K
Y
V
S
S
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
HHSearch
20.00
8%
-5
- C6 -
3WU2
-
PSBT_THEVL
T:
[5-28]
------------------------------------------------------------------------------
T
I
T
Y
V
F
I
F
A
C
I
I
A
L
F
F
F
A
I
F
F
R
E
P
P
R
I
T
A
N
L
W
E
R
F
C
N
W
V
T
S
T
D
N
R
L
Y
V
G
W
F
G
V
I
M
I
P
T
L
L
A
A
T
-
I
C
F
V
I
A
F
I
A
A
P
P
V
D
I
D
G
I
R
E
P
V
S
G
S
L
L
Y
G
N
N
I
I
T
G
A
V
V
P
S
S
N
A
I
G
L
H
F
--
Y
P
I
W
E
A
A
S
L
D
E
W
L
Y
N
G
G
P
Y
Q
L
I
I
F
H
F
L
L
G
A
S
C
Y
M
G
R
Q
W
E
L
S
Y
R
L
G
M
R
P
W
I
C
V
A
Y
S
A
P
L
A
S
A
F
A
V
F
L
I
-------------
Y
P
I
G
Q
G
S
F
S
D
G
M
P
L
G
I
S
G
T
F
N
F
M
I
V
F
Q
A
E
H
N
I
L
M
H
P
F
H
Q
L
--
G
V
A
G
V
F
G
G
A
L
F
C
A
M
H
G
S
L
V
T
S
S
L
I
---
R
E
T
--------
T
E
T
E
S
A
N
Y
-------
G
Y
K
F
G
Q
-------
E
E
E
T
Y
N
I
V
A
A
-----
H
G
Y
F
G
R
L
I
F
Q
Y
A
S
F
N
N
S
R
S
L
H
F
F
L
A
A
W
P
V
V
G
V
W
F
-
A
A
L
G
I
S
T
M
A
F
N
L
N
G
F
N
F
N
H
S
V
I
D
A
K
G
N
V
I
N
T
W
A
D
I
I
N
R
A
N
L
G
M
E
V
---
M
H
E
R
N
A
H
N
F
P
L
D
L
A
-------------------------------