@TOME V2.2
(Nov 2016)
Ref.
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : SC5AA_HUMAN: (2015-12-11 )
MAANSTSDLHTPGTQLSVADIIVITVYFALNVAVGIWSSCRASRNTVNGYFLAGRDMTWWPIGASLFASSEGSGLFIGLAGSGAAGGLAVAGFEWNATYVLLALAWVFVPIYISSEIVTLPEYIQKRYGGQRIRMYLSVLSLLLSVFTKISLDLYAGALFVHICLGWNFYLSTILTLGITALYTIAGGLAAVIYTDALQTLIMVVGAVILTIKAFDQIGGYGQLEAAYAQAIPSRTIANTTCHLPRTDAMHMFRDPHTGDLPWTGMTFGLTIMATWYWCTDQVIVQRSLSARDLNHAKAGSILASYLKMLPMGLIIMPGMISRALFPDDVGCVVPSECLRACGAEVGCSNIAYPKLVMELMPIGLRGLMIAVMLAALMSSLTSIFNSSSTLFTMDIWRRLRPRSGERELLLVGRLVIVALIGVSVAWIPVLQDSNSGQLFIYMQSVTSSLAPPVTAVFVLGVFWRRANEQGAFWGLIAGLVVGATRLVLEFLNPAPPCGEPDTRPAVLGSIHYLHFAVALFALSGAVVVAGSLLTPPPQSVQIENLTWWTLAQDVPLGTKAGDGQTPQKHAFWARVCGFNAILLMCVNIFFYAYFA
Atome Classification :
(20 SA)
------------------------------------------........--.10........20........30........40......-----..--50........60..---------....------..70........80...-...--..90.....-....100...------....110--.---..-------------------.-.-....120.-----.......130.......140.......150.......160.....-----.----.170-.--......------.180-.......190.......200.......210.......220.---------.......230......-----.240.......250........---.260......-.270.......280.......290------......---...300....-----..---------.310--...---....320....---..-----.330...------------....340.....-------..350.......360..--.....370.......380........390-........-400-----------------------.........410.......420......-.430.......440.......450.......460.--------.....---------.-------470---........480.----------......490..-....-----------------.500.......510..---....-.520..-----------------------.--...-.530.......540..----.....550.......560----.......-570.......580.......590......---------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
------------------------------------------MAANSTSD--LHTPGTQ
L
S
V
A
D
I
I
V
I
T
V
Y
F
A
L
N
V
A
V
G
I
W
S
S
C
RASRNTV-----
N
G
--
Y
F
L
AGRD
M
T
W
W
PI
G
---------
A
S
L
F------ASSEG
S
G
L
F
I
G
LAGSGA-AG
G
--
L
A
V
-
A
G
FEW-
N
A
T
Y
V
L
L
A
L
A
------
W
V
F
V
P
----
I
---
Y
I-------------------S-S-
E
I
V
T
L
-
P
E
-----
Y
I
Q
K
RYG
G
Q
R
I
R
M
Y
L
S
V
L
S
L
L
L
S
V
F
T
K
I
S
L
D
L
Y
A
G
A
L
F
V
H
I
CLG
W
-----
N
----
F
Y
L
--
S
--
T
I
L
T
L
G
------
I
T
A
L
-
Y
T
I
A
G
G
L
A
A
V
I
Y
T
D
A
L
Q
T
L
I
M
V
V
G
A
V
I
L
T
I
K
A
F
D
QIGG-Y
G
---------
Q
L
E
A
A
Y
A
Q
AIPSRTIA-----NTTCHLPRT
D
A
M
--
H
MFRDPHT---GDLPWTG
M
T
F
-
G
L
T
I
M
A
T
W
Y
WC
T
D
Q
V
I
V
Q
RSLS--------ARDL
N
H
---
A
K
A
G
S
I
L
A
S
Y
-----
L
K
---------MLPM--
G
L
I
---IM
P
G
M
I
S
RALF---PD-----DVGCV
V
P
------------
S
E
C
L
R
ACGAEVG-------CSNI
A
Y
P
K
L
V
M
E
L
M
P
I
G
--
L
R
G
L
M
I
A
V
M
L
A
A
L
M
S
S
L
-
T
S
I
FNSSS
T
L
--
F
T
M
D
I
W
R
R-L-------------------------RPRSGER
E
L
L
L
V
G
R
L
V
I
V
A
L
I
GV
S
V
A
W
I
-
P
V
LQDSNS
G
Q
L
F
I
Y
M
Q
S
V
T
S
SLAP
P
V
T
A
V
F
V
L
G
V
F
--------
W
R
RAN---------E-------QG----
A
F
W
G
L
I
A
G
L
V
V
G
----------
A
T
R
L
V
L
E
F
LNP-APPC-----------------GEPDTR
P
A
V
L
G
S
I
H
Y
L
---
H
F
A
V
-
A
L
F
A
LS-----------------------G--
A
V
V
-
V
AGSLLTPPPQS
V
Q
I
E----N
L
T
W
W
T
L
AQDVPLGTKAG----DGQTP
Q
K
-
H
A
F
W
A
R
V
C
G
F
N
A
I
L
L
M
C
V
N
I
F
--
F
Y
A
YFA---------------------------
7
HHSearch
99.92
30%
-134
- C8 -
2XQ2
3
SGLT_VIBPH
A:
[9-543]
------------------------------------------------------------
S
F
I
D
I
M
V
F
A
I
Y
V
A
I
I
I
G
V
G
L
W
V
S
------------------------
L
P
W
W
A
V
G
---------
A
S
L
I
------
A
A
N
I
S
A
E
Q
F
I
G
M
S
G
S
G
Y
-
S
I
G
--
L
A
I
-
A
S
Y
E
W
-
M
S
A
I
T
L
I
I
V
G
------
K
Y
F
L
P
----
I
---
F
I
-------------------
E
-
K
-
G
I
Y
T
I
-
P
E
-----
F
V
E
K
R
F
N
K
K
-
L
K
T
I
L
A
V
F
W
I
S
L
Y
I
F
V
N
L
T
S
V
L
Y
L
G
G
L
A
L
E
T
I
L
G
I
-----
P
----
L
M
Y
--
S
--
I
L
G
L
A
L
------
F
A
L
V
-
Y
S
I
Y
G
G
---
V
V
W
T
D
V
I
Q
V
F
F
L
V
L
G
G
F
M
T
T
Y
M
A
V
S
F
I
G
G
-
T
D
---------
G
W
F
A
G
V
S
K
M
V
D
A
----------------
A
P
G
H
F
--
E
M
I
L
D
Q
S
N
PQY
M
N
L
P
G
I
A
V
L
I
G
G
L
W
V
A
N
L
Y
Y
W
G
F
N
Q
Y
I
I
Q
R
T
L
A
--------
A
K
S
V
S
E
---
A
Q
K
G
I
V
F
A
A
F
-----
L
A
---------
L
I
V
P
--
F
L
V
---
V
L
P
G
I
A
A
Y
V
I
T
---
S
D
-----
P
Q
L
M
A
S
L
------------
G
-----
N
L
P
S
A
A
-------
N
A
D
K
A
Y
P
W
L
T
-
Q
F
L
P
V
G
--
V
K
G
V
V
F
A
A
L
A
A
A
I
V
S
S
L
-
A
S
M
L
N
S
T
A
T
I
--
F
T
M
D
I
Y
K
E
Y
I
-------------------------
S
P
D
S
G
D
H
K
L
V
N
V
G
R
T
A
A
V
V
A
L
I
I
A
A
L
I
A
-
P
M
L
G
G
I
--
G
Q
C
F
Q
Y
I
Q
E
Y
T
G
L
V
S
P
G
I
L
A
V
F
L
L
G
L
F
--------
W
K
K
T
T
---------
S
-------
K
G
----
A
I
I
G
V
V
A
S
I
P
F
A
----------
L
F
L
K
F
M
P
------------------------------------
L
S
M
P
F
M
---
D
Q
M
L
-
Y
T
L
L
F
T
-----------------------
M
--
V
V
I
-
A
F
T
S
L
S
T
S
I
N
D
D
D
-
P
K
----
G
I
S
V
T
S
S
M
F
-----------------------
V
T
D
R
S
F
N
I
A
A
Y
G
I
M
I
V
L
A
V
--
L
Y
T
L
F
W
---------------------------
1
PsiBlast_PDB
90.95
32%
-140
- C8 -
2XQ2
3
SGLT_VIBPH
A:
[9-464]
------------------------------------------------------------
S
F
I
D
I
M
V
F
A
I
Y
V
A
I
I
I
G
V
G
L
W
V
S
------------------------
L
P
W
W
A
V
G
---------
A
S
L
I
------
A
A
N
I
S
A
E
Q
F
I
G
M
S
G
S
G
Y
-
S
I
G
--
L
A
I
-
A
S
Y
E
W
-
M
S
A
I
T
L
I
I
V
G
------
K
Y
F
L
P
----
I
---
F
I
-------------------
E
-
K
-
G
I
Y
T
I
-
P
E
-----
F
V
E
K
R
F
-
N
K
K
L
K
T
I
L
A
V
F
W
I
S
L
Y
I
F
V
N
L
T
S
V
L
Y
L
G
G
L
A
L
E
T
I
L
G
I
-----
P
----
L
-
M
--
Y
--
S
I
L
G
L
A
------
L
F
A
L
V
Y
S
I
Y
G
G
---
V
V
W
T
D
V
I
Q
V
F
F
L
V
L
G
G
F
M
T
T
Y
M
A
V
S
F
I
G
G
-
T
D
---------
G
W
F
A
G
V
S
K
M
V
D
A
A
P
-
G
-----
H
F
E
M
I
L
D
Q
S
N
P
Q
--
Y
M
----------
N
L
P
G
I
A
V
L
I
G
G
L
W
V
A
N
L
Y
Y
W
G
F
N
Q
Y
I
I
Q
R
T
L
A
--------
A
K
S
V
S
E
---
A
Q
K
G
I
V
F
A
A
F
-----
L
A
---------
L
I
V
P
--
F
L
V
---
V
L
P
G
I
A
A
Y
V
I
T
---
S
D
P
Q
L
M
A
S
L
G
-----------------
N
L
P
S
A
A
N
A
D
K
------------
A
Y
P
W
L
T
-
Q
F
L
P
V
G
--
V
K
G
V
V
F
A
A
L
A
A
A
I
V
S
S
L
-
A
S
M
L
N
S
T
A
T
I
--
F
T
M
D
I
Y
K
E
Y
I
-------------------------
S
P
D
S
G
D
H
K
L
V
N
V
G
R
T
A
A
V
V
A
L
I
I
A
A
L
I
A
-
P
M
L
--
G
G
I
G
Q
C
F
Q
Y
I
Q
E
Y
T
G
L
V
S
P
G
I
L
A
V
F
L
L
G
L
F
--------
W
K
K
T
T
---------
S
-------
K
G
----
A
I
I
G
V
V
A
S
I
P
F
A
----------
L
F
L
K
F
M
P
L
S
M
P
-
F
M
D
Q
-----------------
M
L
Y
T
L
L
F
T
M
V
V
I
A
F
T
S
---
L
S
T
S
-
I
N
D
D
D
P
-----------------------
K
--
G
I
S
-
V
T
S
S
M
F
V
T
D
R
S
F
N
I
A
A
----
Y
G
I
M
I
V
L
A
V
L
Y
T
L
F
W
V
N
A
----
D
A
E
I
T
L
I
-
I
F
G
V
M
A
G
V
I
G
T
I
L
L
I
S
Y
G
I
K
------------------------------------
17
Fugue
81.89
27%
-81
- C8 -
3DH4
1
?
A:
[52-518]
-------------------------------------------------------------------------------------------------------
A
G
K
S
L
P
W
W
A
V
G
---------
A
S
L
I
------
A
A
N
I
S
A
E
Q
F
I
G
M
S
G
S
G
Y
-
S
I
G
--
L
A
I
-
A
S
Y
E
W
-
M
S
A
I
T
L
I
I
V
G
------
K
Y
F
L
P
----
I
---
F
I
-------------------
E
-
K
-
G
I
Y
T
I
-
P
E
-----
F
V
E
K
R
F
N
-
K
K
L
K
T
I
L
A
V
F
W
I
S
L
Y
I
F
V
N
L
T
S
V
L
Y
L
G
G
L
A
L
E
T
I
L
G
I
-----
P
----
L
M
Y
--
S
--
I
L
G
L
A
L
------
F
A
L
V
-
Y
S
------
I
V
V
W
T
D
V
I
Q
V
F
F
L
V
L
G
G
F
M
T
T
Y
M
A
V
S
F
I
G
G
-
T
D
---------
G
W
F
A
G
V
S
K
M
V
D
A
-------------
A
P
G
H
F
E
M
I
--
L
D
Q
S
N
P
Q
Y
---
M
N
L
P
G
I
A
V
L
I
G
G
L
W
V
A
N
L
Y
Y
W
G
F
N
Q
Y
I
I
Q
R
T
L
A
--------
A
K
S
V
S
E
---
A
Q
K
G
I
V
F
A
A
F
-----
L
K
---------
L
I
V
P
--
F
L
V
---
V
L
P
G
I
A
A
Y
V
I
T
---
S
D
-----
P
Q
L
M
A
S
L
------------
G
D
I
A
A
T
N
L
P
S
A
A
-------
N
A
D
K
A
Y
P
W
L
T
-
Q
F
L
P
V
G
--
V
K
G
V
V
F
A
A
L
A
A
A
I
V
S
S
L
-
A
S
M
L
N
S
T
A
T
I
--
F
T
M
D
I
Y
K
E
-
Y
I------------------------
S
P
D
S
G
D
H
K
L
V
N
V
G
R
T
A
A
V
V
A
L
I
I
A
C
L
I
A
-
P
M
L
G
G
I
--
G
Q
A
F
Q
Y
I
Q
E
Y
T
G
L
V
S
P
G
I
L
A
V
F
L
L
G
L
F
--------
W
K
K
T
T
---------
S
-------
K
G
----
A
I
I
G
V
V
A
S
I
P
F
A
----------
L
F
L
K
F
M
P
L
------------------------------------
S
M
P
F
M
---
D
Q
M
L
-
Y
T
L
L
F
T
-----------------------
M
--
V
V
I
-
A
F
T
S
L
S
T
S
I
N
D
D
D
P
K
G
----
I
S
V
T
S
S
-------------------
M
F
V
T
-
D
R
S
F
N
I
A
A
Y
G
I
M
I
V
L
A
V
L
Y
T
L
--
F
W
V
L
Y
K
---------------------------
2
PsiBlast_PDB
76.29
32%
-82
- C8 -
3DH4
1
?
A:
[52-435]
-------------------------------------------------------------------------------------------------------
A
G
K
S
L
P
W
W
A
V
G
---------
A
S
L
I
------
A
A
N
I
S
A
E
Q
F
I
G
M
S
G
S
G
Y
-
S
I
G
--
L
A
I
-
A
S
Y
E
W
-
M
S
A
I
T
L
I
I
V
G
------
K
Y
F
L
P
----
I
---
F
I
-------------------
E
-
K
-
G
I
Y
T
I
-
P
E
-----
F
V
E
K
R
F
-
N
K
K
L
K
T
I
L
A
V
F
W
I
S
L
Y
I
F
V
N
L
T
S
V
L
Y
L
G
G
L
A
L
E
T
I
L
G
I
-----
P
----
L
-
M
--
Y
--
S
I
L
G
L
A
------
L
F
A
L
V
Y
S
I
------
V
V
W
T
D
V
I
Q
V
F
F
L
V
L
G
G
F
M
T
T
Y
M
A
V
S
F
I
G
G
-
T
D
---------
G
W
F
A
G
V
-----
S
K
M
V
D
-----
A
A
P
G
H
F
---
E
M
I
--
L
D
Q
S
N
P
Q
Y
---
M
N
L
P
G
I
A
V
L
I
G
G
L
W
V
A
N
L
Y
Y
W
G
F
N
Q
Y
I
I
Q
R
T
L
A
--------
A
K
S
V
S
E
---
A
Q
K
G
I
V
F
A
A
F
-----
L
K
---------
L
I
V
P
--
F
L
V
---
V
L
P
G
I
A
A
Y
V
I
T
---
S
D
P
Q
L
M
A
S
L
G
D
I
A
A
------------
T
N
L
P
S
A
A
N
A
D
K
------------
A
Y
P
W
L
T
-
Q
F
L
P
V
G
--
V
K
G
V
V
F
A
A
L
A
A
A
I
V
S
S
L
-
A
S
M
L
N
S
T
A
T
I
--
F
T
M
D
I
Y
K
E
Y
I
-------------------------
S
P
D
S
G
D
H
K
L
V
N
V
G
R
T
A
A
V
V
A
L
I
I
A
C
L
I
A
-
P
M
L
--
G
G
I
G
Q
A
F
Q
Y
I
Q
E
Y
T
G
L
V
S
P
G
I
L
A
V
F
L
L
G
L
F
--------
W
K
K
T
T
---------
S
-------
K
G
----
A
I
I
G
V
V
A
S
I
P
F
A
----------
L
F
L
K
F
M
P
L
S
M
P
-
F
M
D
Q
-----------------
M
L
Y
T
L
L
F
T
M
V
V
I
A
F
T
S
---
L
S
T
S
-
I
N
D
D
D
P
-----------------------
K
--
G
I
S
-
V
T
S
S
M
F
V
T
D
R
S
F
N
I
A
A
----
Y
G
I
M
I
V
L
A
V
L
Y
T
L
F
W
V
L
Y
----
K
---------------------------------------------------------------
5
PsiBlast_CBE
75.66
32%
-82
- C8 -
3DH4
1
?
C:
[52-435]
-------------------------------------------------------------------------------------------------------
A
G
K
S
L
P
W
W
A
V
G
---------
A
S
L
I
------
A
A
N
I
S
A
E
Q
F
I
G
M
S
G
S
G
Y
-
S
I
G
--
L
A
I
-
A
S
Y
E
W
-
M
S
A
I
T
L
I
I
V
G
------
K
Y
F
L
P
----
I
---
F
I
-------------------
E
-
K
-
G
I
Y
T
I
-
P
E
-----
F
V
E
K
R
F
-
N
K
K
L
K
T
I
L
A
V
F
W
I
S
L
Y
I
F
V
N
L
T
S
V
L
Y
L
G
G
L
A
L
E
T
I
L
G
I
-----
P
----
L
-
M
--
Y
--
S
I
L
G
L
A
------
L
F
A
L
V
Y
S
I
------
V
V
W
T
D
V
I
Q
V
F
F
L
V
L
G
G
F
M
T
T
Y
M
A
V
S
F
I
G
G
-
T
D
---------
G
W
F
A
G
V
-----
S
K
M
V
D
-----
A
A
P
G
H
F
---
E
M
I
--
L
D
Q
S
N
P
Q
Y
---
M
N
L
P
G
I
A
V
L
I
G
G
L
W
V
A
N
L
Y
Y
W
G
F
N
Q
Y
I
I
Q
R
T
L
A
--------
A
K
S
V
S
E
---
A
Q
K
G
I
V
F
A
A
F
-----
L
K
---------
L
I
V
P
--
F
L
V
---
V
L
P
G
I
A
A
Y
V
I
T
---
S
D
PQLMA
S
L
G
D
I
A
A
------------
T
N
L
P
S
A
A
N
A
D
K
------------
A
Y
P
W
L
T
-
Q
F
L
P
V
G
--
V
K
G
V
V
F
A
A
L
A
A
A
I
V
S
S
L
-
A
S
M
L
N
S
T
A
T
I
--
F
T
M
D
I
Y
K
E
Y
I
-------------------------
S
P
D
S
G
D
H
K
L
V
N
V
G
R
T
A
A
V
V
A
L
I
I
A
C
L
I
A
-
P
M
L
--
G
G
I
G
Q
A
F
Q
Y
I
Q
E
Y
T
G
L
V
S
P
G
I
L
A
V
F
L
L
G
L
F
--------
W
K
K
T
T
---------
S
-------
K
G
----
A
I
I
G
V
V
A
S
I
P
F
A
----------
L
F
L
K
F
M
P
L
S
M
P
-
F
M
D
Q
-----------------
M
L
Y
T
L
L
F
T
M
V
V
I
A
F
T
S
---
L
S
T
S
-
I
N
D
D
D
P
-----------------------
K
--
G
I
S
-
V
T
S
S
M
F
V
T
D
R
S
F
N
I
A
A
----
Y
G
I
M
I
V
L
A
V
L
Y
T
L
F
W
V
L
Y
----
K
---------------------------------------------------------------
6
PsiBlast_CBE
75.63
32%
-82
- C8 -
3DH4
1
?
B:
[52-435]
-------------------------------------------------------------------------------------------------------
A
G
K
S
L
P
W
W
A
V
G
---------
A
S
L
I
------
A
A
N
I
S
A
E
Q
F
I
G
M
S
G
S
G
Y
-
S
I
G
--
L
A
I
-
A
S
Y
E
W
-
M
S
A
I
T
L
I
I
V
G
------
K
Y
F
L
P
----
I
---
F
I
-------------------
E
-
K
-
G
I
Y
T
I
-
P
E
-----
F
V
E
K
R
F
-
N
K
K
L
K
T
I
L
A
V
F
W
I
S
L
Y
I
F
V
N
L
T
S
V
L
Y
L
G
G
L
A
L
E
T
I
L
G
I
-----
P
----
L
-
M
--
Y
--
S
I
L
G
L
A
------
L
F
A
L
V
Y
S
I
------
V
V
W
T
D
V
I
Q
V
F
F
L
V
L
G
G
F
M
T
T
Y
M
A
V
S
F
I
G
G
-
T
D
---------
G
W
F
A
G
V
-----
S
K
M
V
D
-----
A
A
P
G
H
F
---
E
M
I
--
L
D
Q
S
N
P
Q
Y
---
M
N
L
P
G
I
A
V
L
I
G
G
L
W
V
A
N
L
Y
Y
W
G
F
N
Q
Y
I
I
Q
R
T
L
A
--------
A
K
S
V
S
E
---
A
Q
K
G
I
V
F
A
A
F
-----
L
K
---------
L
I
V
P
--
F
L
V
---
V
L
P
G
I
A
A
Y
V
I
T
---
S
D
PQLMA
S
L
G
D
I
A
A
------------
T
N
L
P
S
A
A
N
A
D
K
------------
A
Y
P
W
L
T
-
Q
F
L
P
V
G
--
V
K
G
V
V
F
A
A
L
A
A
A
I
V
S
S
L
-
A
S
M
L
N
S
T
A
T
I
--
F
T
M
D
I
Y
K
E
Y
I
-------------------------
S
P
D
S
G
D
H
K
L
V
N
V
G
R
T
A
A
V
V
A
L
I
I
A
C
L
I
A
-
P
M
L
--
G
G
I
G
Q
A
F
Q
Y
I
Q
E
Y
T
G
L
V
S
P
G
I
L
A
V
F
L
L
G
L
F
--------
W
K
K
T
T
---------
S
-------
K
G
----
A
I
I
G
V
V
A
S
I
P
F
A
----------
L
F
L
K
F
M
P
L
S
M
P
-
F
M
D
Q
-----------------
M
L
Y
T
L
L
F
T
M
V
V
I
A
F
T
S
---
L
S
T
S
-
I
N
D
D
D
P
-----------------------
K
--
G
I
S
-
V
T
S
S
M
F
V
T
D
R
S
F
N
I
A
A
----
Y
G
I
M
I
V
L
A
V
L
Y
T
L
F
W
V
L
Y
----
K
---------------------------------------------------------------
4
PsiBlast_CBE
75.57
32%
-82
- C8 -
3DH4
1
?
D:
[52-435]
-------------------------------------------------------------------------------------------------------
A
G
K
S
L
P
W
W
A
V
G
---------
A
S
L
I
------
A
A
N
I
S
A
E
Q
F
I
G
M
S
G
S
G
Y
-
S
I
G
--
L
A
I
-
A
S
Y
E
W
-
M
S
A
I
T
L
I
I
V
G
------
K
Y
F
L
P
----
I
---
F
I
-------------------
E
-
K
-
G
I
Y
T
I
-
P
E
-----
F
V
E
K
R
F
-
N
K
K
L
K
T
I
L
A
V
F
W
I
S
L
Y
I
F
V
N
L
T
S
V
L
Y
L
G
G
L
A
L
E
T
I
L
G
I
-----
P
----
L
-
M
--
Y
--
S
I
L
G
L
A
------
L
F
A
L
V
Y
S
I
------
V
V
W
T
D
V
I
Q
V
F
F
L
V
L
G
G
F
M
T
T
Y
M
A
V
S
F
I
G
G
-
T
D
---------
G
W
F
A
G
V
-----
S
K
M
V
D
-----
A
A
P
G
H
F
---
E
M
I
--
L
D
Q
S
N
P
Q
Y
---
M
N
L
P
G
I
A
V
L
I
G
G
L
W
V
A
N
L
Y
Y
W
G
F
N
Q
Y
I
I
Q
R
T
L
A
--------
A
K
S
V
S
E
---
A
Q
K
G
I
V
F
A
A
F
-----
L
K
---------
L
I
V
P
--
F
L
V
---
V
L
P
G
I
A
A
Y
V
I
T
---
S
D
PQLMA
S
L
G
D
I
A
A
------------
T
N
L
P
S
A
A
N
A
D
K
------------
A
Y
P
W
L
T
-
Q
F
L
P
V
G
--
V
K
G
V
V
F
A
A
L
A
A
A
I
V
S
S
L
-
A
S
M
L
N
S
T
A
T
I
--
F
T
M
D
I
Y
K
E
Y
I
-------------------------
S
P
D
S
G
D
H
K
L
V
N
V
G
R
T
A
A
V
V
A
L
I
I
A
C
L
I
A
-
P
M
L
--
G
G
I
G
Q
A
F
Q
Y
I
Q
E
Y
T
G
L
V
S
P
G
I
L
A
V
F
L
L
G
L
F
--------
W
K
K
T
T
---------
S
-------
K
G
----
A
I
I
G
V
V
A
S
I
P
F
A
----------
L
F
L
K
F
M
P
L
S
M
P
-
F
M
D
Q
-----------------
M
L
Y
T
L
L
F
T
M
V
V
I
A
F
T
S
---
L
S
T
S
-
I
N
D
D
D
P
-----------------------
K
--
G
I
S
-
V
T
S
S
M
F
V
T
D
R
S
F
N
I
A
A
----
Y
G
I
M
I
V
L
A
V
L
Y
T
L
F
W
V
L
Y
----
K
---------------------------------------------------------------
19
Fugue
67.41
16%
-123
- C5 -
4J5T
4
CWH41_YEAST
A:
[1-811]
A
E
F
M
E
E
Y
Q
K
F
T
N
E
S
L
LWAPYRSNCY
F
G
M
R
P
R
YVHESPL
I
M
G
I
M
W
F
N
S
L
S
Q
DG
L
H
S
L
R
H
F
A
T
P
Q
D
K
L
Q
K
Y
G
W
E
V
Y
D
P
R
I
G
G
K
E
V
F
I
D
E
K
N
N
L
-----
N
L
T
V
Y
F
V
K
S
K
N
G
E
N
W
S
V
R
---------
V
Q
G
E
P
LDPKR
P
S
T
A
S
V
V
L
Y
F
S
Q
N
G
G
E
I
-
D
G
K
S
S
L
A
M
-
I
G
H
D
G
-
P
N
D
M
K
F
F
G
Y
S
KEL
G
E
Y
H
L
T
V
K
----
D
---
N
F
G
H
Y
F
KNPEYETMEVAPGSD
C
-
S
-
K
T
S
H
L
-
S
L
-----
Q
I
P
D
K
E
V
W
K
A
R
D
V
F
Q
S
L
V
S
D
S
I
R
D
I
L
E
R
P
A
D
L
I
P
S
V
L
T
I
R
N
L
Y
N
F
-----
N
PGN
F
H
Y
I
--
Q
--
K
T
F
D
L
T
KKD
G
F
Q
F
D
I
T
-
Y
N
K
L
G
T
T
Q
S
I
--
S
T
R
E
Q
V
T
E
L
I
T
W
S
L
N
E
I
N
A
R
F
D
K
Q
F
S
-
F
G
EGPDSIES
V
E
V
K
R
R
F
A
L
E
T
L
S
N
L
L
G
G
I
G
Y
F
Y
G
N
Q
L
I
D
R
E
T
E
F
DE
S
Q
F
T
E
I
K
L
---
L
N
A
K
E
E
G
P
F
E
-
L
F
T
S
V
P
S
R
G
F
F
P
R
G
F
Y
W
D
E
G
F
H
--------
L
L
Q
I
M
E
Y
D
F
D
L
A
F
E
I
L
A
S
W
-----
F
E
---------
M
I
E
D
DS
G
W
I
AR
E
I
I
L
G
N
E
A
R
S
K
V
---
P
Q
-----
E
F
Q
V
Q
N
P
NIANPP
T
L
L
L
A
F
S
E
M
L
S
R
A
I
E
N
I
G
DFM----
T
N
N
L
E
A
N
P
G
L
L
T
E
Y
A
K
K
--
I
Y
P
K
L
L
K
H
Y
N
W
F
R
K
S
Q
T
-
G
L
I
D
E
Y
E
E
I
L
--
E
D
E
G
I
W
D
K
-
I
HKNEVYRWVGRTFTHCLPSGMDDYP
R
A
Q
P
P
D
V
A
E
L
N
V
D
A
L
A
W
V
G
V
M
T
R
S
M
K
Q
I
A
H
V
L
K
L
T
Q
D
E
Q
R
Y
A
Q
I
E
Q
E
V
V
E
N
L
D
L
L
H
W
S
E
N
D
N
C
Y
C
D
I
S
I
DPE
D
D
E
I
R
---------
E
-------
F
V
----
C
H
E
G
Y
V
S
V
L
P
F
A
L
KLIPKNS
P
K
L
E
K
V
V
A
L
M
S
D
P
-
E
K
I
F
SDYGLLSLSRQDDYFGK
D
E
N
Y
W
R
G
P
I
W
M
N
I
N
Y
L
---
C
L
D
A
-
M
R
Y
Y
Y
P
-----------------------
E
--
V
I
L
D
V
A
G
----
E
A
S
N
A
K
K
L
Y
----
Q
S
L
K
I
N
L
S
N
N
I
Y
K
V
W
E
E
Q
GYCY
E
N
Y
S
P
I
D
G
H
G
T
G
A
E
--
H
F
T
G
W
T
A
L
V
V
N
I
L
G
R
F
R
S
H
H
H
H
HH------------------------
25
Fugue
66.65
19%
-118
- C6 -
3ACP
-
RPN14_YEAST
A:
[1-417]
------------------------------------------
M
T
-------------
K
T
I
T
V
A
H
I
Q
--------------------------------------------
Y
D
F
K
---------
A
V
L
E
------
E
N
D
E
N
D
D
E
F
Y
I
N
V
D
K
N
L
-
N
E
-------------------------------------------
I
-------------------
K
-
E
-
H
K
I
V
V
-
L
G
-----
N
S
R
G
V
D
A
G
K
G
------------
N
T
F
E
K
V
G
S
H
L
Y
K
A
R
L
D
-----
G
H
-----
D
----
F
L
F
--
N
--
T
I
I
R
D
G
------
S
K
M
L
-
K
R
---
A
D
Y
T
A
V
D
T
A
K
L
Q
M
R
R
F
I
L
G
T
T
E
G
D
I
K
V
L
D
S
N
F
N
----------------------
L
Q
R
E
I
D
-----
Q
--
A
H
V
S
E
I
T
K
L
--
K
F
F
--
P
S
G
---
E
A
L
I
S
S
S
Q
D
M
-
Q
L
K
I
W
S
V
K
D
G
S
N
P
R
T
L
I
G
H
R
A
T
--------
V
T
D
I
A
I
---
I
D
R
G
R
N
V
L
S
A
S
LDGT
I
R
---------
L
W
E
C
--
G
T
G
---
T
T
I
H
T
F
N
R
K
E
N
---
P
H
-----
D
G
--------------------------------------------------------------------
V
N
S
I
-
A
L
F
V
G
T
D
R
Q
L
--
H
E
I
S
-------------------------------
T
S
K
K
N
N
L
E
F
G
T
Y
G
K
Y
V
I
A
G
H
V
S
G
V
I
T
V
H
-
N
V
F
S
K
E
Q
T
I
Q
L
-------
P
S
K
F
T
C
S
C
N
S
L
T
V
D
G
-------------
N
N
---------
A
-------
N
Y
----
I
Y
A
G
Y
E
N
G
M
L
A
Q
----------
W
D
-----
L
R
S
P
-
E
C
P
V
-----------------
G
E
F
L
I
N
E
G
T
--
P
I
N
N
V
---
Y
F
A
A
G
A
L
F
V
S
S
-----------------------
G
F
D
T
S
I
-
K
L
D
I
I
S
D
P
E
S
E
R
P
A
I
E
----
F
E
T
P
T
F
L
V
S
N
-------------
D
D
E
V
S
Q
-
F
C
Y
V
S
D
D
E
S
N
G
E
V
L
E
V
G
K
N
N
F
--
C
A
L
Y
N
L
SNP------------------------
9
HHSearch
63.14
13%
-115
- C8 -
2JLN
-
?
A:
[22-452]
------------------------------------------------------------------------------------------------------
Y
A
E
R
S
V
G
P
F
S
L
A
---------
A
I
W
F
------
A
M
A
I
Q
V
A
I
F
I
A
A
G
Q
--
M
-
T
S
S
--
F
Q
V
-
W
Q
V
I
V
-
A
I
A
A
G
C
T
I
A
V
------
I
L
L
F
F
----
T
Q
S
A
A
I
-------------------
R
-
W
-
G
-
I
N
F
-
T
V
-----
A
A
R
M
P
F
G
I
R
-
G
S
L
I
P
I
T
L
K
A
L
L
S
-
L
F
W
F
G
F
Q
T
W
L
G
A
L
A
L
D
E
I
T
R
L
L
TGFT
N
----
L
P
L
--
W
--
I
V
I
F
G
A
------
I
Q
V
V
-
T
T
-
F
Y
G
I
T
F
I
R
W
M
N
V
F
A
S
P
V
L
L
A
M
G
V
Y
M
V
Y
L
M
L
D
G
A
D
V
S
L
G
---------
E
V
M
S
M
G
G
E
----------------------------------
N
---
P
G
M
P
F
S
-
T
A
I
-
M
I
F
V
G
G
W
I
A
V
V
V
S
I
H
D
I
V
K
E
C
K
VDPNAS
R
E
G
Q
T
K
A
D
---
A
R
Y
A
T
A
-
Q
W
L
-----
G
M
---------
V
P
A
S
--
I
I
F
---
G
F
I
G
A
A
S
M
V
L
V
---
G
E
-----------------------------------
W
-------
N
P
V
I
A
I
T
E
V
V
G
G
-
V
S
I
P
--
M
A
I
L
F
Q
V
F
V
L
L
A
T
W
S
T
N
P
A
A
N
L
L
S
P
A
Y
T
--
L
C
S
-
T
F
P
R
-
V
-------------------------
F
T
---------
F
K
T
G
-
V
I
V
S
A
V
V
G
L
L
M
M
-
P
W
--
Q
F
--
A
G
V
L
N
T
F
L
N
L
L
A
S
A
L
G
P
L
A
G
I
M
I
S
D
Y
F
--------
L
V
R
R
R
RIS
L
H
D
L
Y
R
T
KGIYTYW
R
G
VN
W
V
A
L
A
V
Y
A
V
A
L
A
V
S
----------
F
L
T
P
D
-----------------------------------------------
L
M
F
V
-
T
G
L
I
A
A
-----------------------
L
--
L
L
H
-
I
P
A
M
R
W
V
A
K
T
F
P
L
F
S
E
----
A
E
S
R
N
E
D
Y
L
R
P
I
G
P
------------------------------------------------------------------------
20
Fugue
62.93
12%
-115
- C4 -
3RCE
1
PGLB_CAMLR
A:
[2-711]
-----------------------------------------E
L
Q
Q
N
F
T
D
N
--
N
S
I
K
Y
T
C
I
L
I
L
I
A
F
A
F
S
V
L
C
R
L
Y
W
V
A
W
A
S
E
F
Y
E
F
F
F
N
D
Q
L
M
I
T
T
N
D
--
G
Y
A
F
A
E
G
A
R
D
M
I
A
G
FHQPNDLSY
F
G
S
S
------
L
S
T
L
T
Y
W
L
Y
S
I
L
P
F
S
F
E
-
S
I
I
--
L
Y
M
-
S
T
F
F
A
-
S
L
I
V
V
P
I
I
L
I
------
A
R
E
Y
K
L
T
T
Y
G
---
F
I
-------------------
A
-
A
-
L
L
G
S
I
A
N
S
-----
Y
Y
N
R
T
M
S
G
Y
Y
D
T
D
M
L
V
L
V
L
P
M
L
I
L
L
T
F
I
R
L
T
I
N
K
D
I
F
T
L
L
L
S
P
I
F
-----
I
----
M
I
Y
--
L
--
W
W
Y
P
S
S
------
Y
S
L
N
-
F
A
M
I
G
L
F
G
L
Y
T
L
V
F
H
R
K
E
K
I
F
Y
L
A
I
A
L
M
I
I
A
L
S
M
L
A
W
Q
-
Y
K
---------
L
A
L
I
V
L
L
F
A
I
F
A
F
K
E
E
-----
K
I
N
F
Y
M
I
W
A
L
I
F
--
I
S
I
S
I
L
H
L
---
S
G
G
A
F
M
Y
F
N
V
-
N
E
T
I
M
E
V
N
T
I
D
P
E
V
F
M
Q
R
I
S
S
S
--------
V
L
V
F
I
L
---
S
F
I
G
F
I
L
L
C
K
-----
D
H
K
S
M
------
L
L
A
L
--
P
M
L
---
A
L
G
F
M
A
L
R
A
G
L
---
R
F
-----
T
I
Y
A
V
P
V
------------
M
A
L
G
F
G
Y
F
L
Y
A
F
-------
F
N
F
L
E
K
K
Q
I
K
L
S
L
R
N
K
N
--
I
L
L
I
L
I
A
F
F
S
I
S
P
A
L
M
H
-
I
Y
Y
Y
K
S
S
T
V
F
T
S
Y
E
A
S
I
L
N
D
-
L
-------------------------
K
N
K
A
Q
R
E
D
Y
V
V
A
W
W
D
Y
G
Y
P
I
R
Y
Y
S
D
V
K
T
-
L
I
D
G
G
K
H
L
G
K
D
N
F
F
S
S
F
V
L
S
K
E
Q
I
P
A
A
N
M
A
R
L
S
V
E
--------
Y
T
E
K
S
---------
F
-------
K
E
----
N
Y
P
D
V
L
K
A
M
V
K
D
Y
NQTS-----
A
K
D
F
L
E
S
L
N
D
K
-
N
F
K
F
-----------------
D
T
N
K
T
R
D
V
Y
I
Y
M
P
Y
R
M
LRI
M
P
V
V
-
A
Q
F
A
N
T
NPDNGEQEKS
L
F
F
S
Q
A
N
A
I
A
QDG
S
--
V
M
L
-
D
N
G
V
E
I
I
N
D
F
R
A
L
K
V
E
G
A
S
I
P
L
K
A
F
V
D
I
E
S
I
T
N
G
K
F
Y
Y
----
N
E
I
D
S
K
A
-
Q
I
Y
L
L
F
L
R
E
Y
K
S
F
V
I
L
D
E
S
L
Y
--
N
S
A
Y
I
Q
M
F
L
LNQYDQDLFEQVTNDTR
A
K
I
Y
R
L
K
22
Fugue
51.43
16%
-104
- C3 -
4P6V
2
NQRB_VIBCH
B:
[38-409]
---------------------------------------------------------------------------------------------------------------------------
G
L
V
T
------
K
R
S
S
H
V
R
D
S
V
D
L
K
R
I
M
I
-
M
V
W
--
L
A
V
F
P
A
M
F
W
-
G
M
Y
N
A
G
G
Q
A
I
------
A
A
L
N
H
----
L
---
Y
S
-------------------
G
-
D
-
Q
L
A
A
I
-
V
A
G
N
W
H
Y
W
L
T
E
M
L
G
G
T
M
G
S
K
M
L
L
G
A
T
Y
F
L
P
I
Y
A
T
V
F
I
V
G
G
F
W
E
V
L
F
C
M
V
R
K
H
-----
E
V
N
E
G
F
F
V
--
T
--
S
I
L
F
A
L
------
I
V
P
P
--
T
L
P
L
W
Q
A
A
L
G
I
T
F
G
V
V
V
A
K
E
V
F
G
G
T
G
R
N
F
L
N
-
P
A
L
A
G
-
R
A
---------
F
L
F
F
A
Y
P
A
Q
I
S
G
D
L
V
W
-----
T
A
A
D
G
Y
S
G
A
T
A
L
--
S
Q
W
A
Q
G
G
A
---
G
A
L
I
N
I
P
G
S
I
-
G
E
V
S
T
L
A
L
M
I
G
A
A
F
I
V
Y
M
G
I
A
S
--------
W
R
I
I
G
G
---
V
M
I
G
M
I
L
L
S
T
-----
L
F
N
V
IGSDTNA
M
F
N
M
--
P
W
H
---
L
V
L
G
G
F
A
F
G
M
F
FMA
T
D
-----
P
V
S
A
S
F
T
------------
N
S
G
K
W
A
Y
G
I
L
I
G
--------
V
M
C
V
L
I
R
V
V
N
P
A
Y
P
E
G
M
-
M
L
A
I
L
F
A
N
L
F
A
P
L
F
D
H
V
-
V
V
E
R
N
I
K
R
R
L
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
HHSearch
39.00
16%
-82
- C8 -
3GIA
3
Y609_METJA
A:
[5-166]
--------------------------------------------------------------------------------------------------------
N
K
K
L
S
L
W
E
A
V
---------
S
M
A
V
------
G
V
M
I
G
A
S
I
F
S
I
-
F
G
V
G
A
K
I
A
G
--
R
N
L
--
P
E
T
F
I
L
S
G
I
Y
A
L
L
V
A
------
Y
S
Y
T
K
----
L
---
G
A
-------------------
K
I
V
-
S
N
A
G
P
-
I
A
-----
F
I
H
K
A
I
G
D
N
I
I
T
G
A
L
S
I
L
L
W
M
S
Y
V
-
I
S
I
A
L
F
A
K
G
F
A
G
Y
F
L
P
L
I
N
A
-----
P
IN--
T
F
N
I
A
I
--
T
E
I
G
I
V
------
A
F
F
T
-
A
L
N
F
F
G
S
K
A
V
G
R
A
E
F
F
I
V
L
V
K
L
L
I
L
G
L
F
I
F
A
G
L
I
T
I
H
P
-
S
Y
---------
V
I
P
D
L
A
P
S
A
V
S
G
M
I
F
A
-----
S
A
I
F
F
L
S
Y
M
G
F
G
--
V
I
T
N
A
S
E
H
---
I
E
N
P
K
K
N
V
P
R
-
A
I
F
I
S
I
L
I
V
M
F
V
Y
V
G
V
A
I
S
A
I
G
--------
N
L
P
I
D
E
---
L
I
K
A
S
E
N
A
L
A
-----
V
A
---------
A
K
P
F
--
L
G
N
---
L
G
F
L
L
I
S
I
G
A
L
---
F
S
-----
I
S
S
A
M
N
A
------------
T
I
Y
G
G
A
N
V
A
Y
S
L
-------
A
K
D
G
E
L
P
E
F
F
E
R
K
V
W
F
K
--
S
T
E
G
L
Y
I
T
S
A
L
G
V
L
F
A
L
-
L
F
N
M
E
G
V
A
S
I
--
T
S
A
V
F
M
V
I
-
Y
-------------------------
L
F
V
I
L
S
H
Y
I
L
I
D
E
V
G
G
R
K
E
I
V
I
F
S
F
I
V
V
-
L
G
V
F
L
L
L
L
Y
Y
Q
W
I
T
N
R
F
V
F
Y
G
I
I
A
T
F
I
G
V
L
I
F
E
I
I
--------
Y
R
K
V
T
---------
K
-------
R
T
----
F
S
N
N
M
Y
V
K
S
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
HHSearch
38.13
13%
-88
- C8 -
3L1L
2
ADIC_ECO57
A:
[7-168]
--------------------------------------------------------------------------------------------------------
A
H
K
V
G
L
I
P
V
T
---------
L
M
V
S
------
G
A
I
M
G
S
G
V
F
L
L
-
P
A
N
L
A
-
S
T
G
--
G
I
A
-
I
Y
G
W
L
-
V
T
I
I
G
A
L
G
L
S
------
M
V
Y
A
K
----
M
---
S
F
-------------------
L
-
D
P
S
P
G
G
S
-
Y
A
-----
Y
A
R
R
C
F
G
P
F
-
L
G
Y
Q
T
N
V
L
Y
W
L
A
C
W
-
I
G
N
I
A
M
V
V
I
G
V
G
Y
L
S
Y
F
F
P
I
-----
L
KD--
P
W
V
--
L
T
I
T
C
V
V
V
L
------
W
I
F
V
-
L
L
N
I
V
G
P
K
M
I
T
R
V
Q
A
V
A
T
V
L
A
L
I
P
I
V
G
I
A
V
F
G
W
F
W
F
R
G
-
E
T
---------
Y
M
A
A
I
Q
S
T
L
N
V
T
L
W
S
F
-----
I
G
V
E
S
A
S
V
A
A
G
V
--
V
K
N
P
K
R
N
V
---
P
I
A
T
I
G
G
V
L
I
-
A
A
V
C
Y
V
L
S
T
T
A
I
M
G
M
I
P
N
A
A
L
R
--------
V
S
A
S
P
F
---
G
D
A
A
R
M
A
L
G
D
-----
T
A
---------
G
A
I
V
--
S
F
C
---
A
A
A
G
C
L
G
S
L
G
G
---
W
T
-----
L
L
A
G
Q
T
A
------------
K
A
A
A
D
D
G
L
F
P
P
I
-------
F
A
R
V
N
K
A
G
T
P
V
A
G
L
I
I
V
--
G
I
L
M
T
I
F
Q
L
S
S
I
S
P
N
A
T
-
K
E
F
G
L
V
S
S
V
S
--
V
I
F
T
L
V
P
Y
-
L
-------------------------
Y
T
C
A
A
L
L
L
L
G
H
G
H
F
G
K
A
R
P
A
Y
L
A
V
T
T
I
A
-
F
L
Y
C
I
W
A
V
V
G
S
G
A
K
E
V
M
W
S
F
V
T
L
M
V
I
T
A
M
Y
A
L
N
Y
N
--------
R
L
H
K
N
---------
P
-------
Y
P
----
L
D
A
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
37.14
28%
-23
* C7 *
3LEX
1
?
H:
[68-144]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
-
S
I
T
R
D
T
S
E
N
Q
F
F
L
Q
L
H
S
V
T
----
P
E
D
T
A
T
Y
----
F
--------
C
A
Y
G
N
---------
Y
-------
L
P
----
A
Y
W
G
Q
G
T
L
V
T
V
S
----------
A
A
K
T
T
A
P
S
V
Y
P
L
A
P
V
----------------------
G
S
S
V
T
L
G
C
L
V
K
G
---
Y
F
P
E
-
P
V
T
L
T
W
-----------------------
N
--
S
G
S
-
L
S
S
G
V
H
T
F
P
A
V
L
Q
S
D
L
----
Y
T
L
S
S
S
V
T
V
T
S
S
T
W
P
S
Q
S
----
I
T
C
N
V
A
H
-
P
A
S
S
T
K
V
D
K
K
I
E
P
R
G
-----------------------------------------
18
Fugue
30.77
34%
159
- C8 -
1M2S
-
KA162_MESMA
A:
[1-37]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
G
---
L
I
-----
D
V
K
C
F
A
S
------------
S
E
C
W
T
A
C
K
K
V
T
G
SGQ
G
K
--
C
Q
N
N
Q
C
R
C
Y
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
HHSearch
30.18
8%
-38
- C8 -
2WSW
1
?
A:
[338-443]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
F
L
A
R
I
S
K
--------
G
R
T
V
R
E
---
L
C
L
G
M
V
S
G
L
T
-----
A
G
---------
T
W
L
I
----
W
---
T
I
L
G
G
N
T
L
Q
L
I
---
D
Q
-------
N
I
L
N
I
-----------------
P
Q
L
I
D
Q
Y
-------
G
V
P
R
A
I
I
E
T
W
-
A
A
L
P
L
S
T
A
T
M
W
G
F
F
I
L
C
F
I
A
T
V
T
L
I
-
N
A
C
S
Y
T
L
A
M
S
--
T
C
R
S
M
K
E
G
-
A
-------------------------
D
P
P
L
L
V
R
I
G
W
S
V
L
V
G
I
I
G
I
I
L
L
A
L
G
G
L
K
-
P
I
Q
T
A
I
I
A
G
G
C
P
L
F
F
V
N
I
M
V
T
L
S
F
I
K
D
A
K
V
H
W
K
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
Fugue
26.31
50%
506
- C8 -
2FQC
1
A:
[1-25]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
---
P
R
-----------
P
------------
R
I
C
N
L
A
C
R
A
G
I
G
HKYPFCH
C
R
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26
Fugue
24.99
23%
227
* C8 *
1Q90
3
PETG_CHLRE
G:
[1-30]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
V
E
P
L
L
C
G
I
V
L
G
L
V
P
V
T
--
I
A
G
L
F
V
T
A
Y
L
Q
Y
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
HHSearch
21.32
4%
341
- C8 -
1WAZ
-
?
A:
[41-65]
------------------------------------------------------------
G
Y
L
D
Y
V
L
L
P
A
L
A
I
F
I
G
L
T
I
Y
A
I
Q
R
K
R
Q
A
D
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------