@TOME V2.2
(Nov 2016)
Ref.
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : SCMC2_HUMAN: (2015-12-12 )
MLCLCLYVPVIGEAQTEFQYFESKGLPAELKSIFKLSVFIPSQEFSTYRQWKQKIVQAGDKDLDGQLDFEEFVHYLQDHEKKLRLVFKSLDKKNDGRIDAQEIMQSLRDLGVKISEQQAEKILKSMDKNGTMTIDWNEWRDYHLLHPVENIPEIILYWKHSTIFDVGENLTVPDEFTVEERQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGAIAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKITLGVQSR
Atome Classification :
(20 SA)
.........10........20........30.....-----...40.......---------.50........60........70.----......---------.------80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210....-..------.-------220-----..-------.-----.....230.......240.......250.......260.......270----.....-----...---280.......-----290.......300.......310---....-----.....320.......330.......340.......350.......360.......370.......380.......390.......400.......410--.....--..420--.......430.......440.......450.......460.......
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
M
L
C
L
C
L
YVPVIGEAQT
E
F
Q
Y
F
ESKGL
P
A
E
L
K
S
I
F
K
L
-----
S
V
F
IP
S
Q
E
F
S
T
Y
---------
R
Q
W
K
Q
K
I
V
QAGDKDLDGQL
D
F
E
E
F
----
V
H
Y
L
Q
D
---------
H
------
E
K
K
L
R
L
V
F
K
S
LDKKNDGRI
D
A
Q
E
I
M
Q
S
L
R
D
LGVKI
S
E
Q
Q
A
E
K
I
L
K
S
MDKNG
T
M
T
I
DWNEW
R
D
Y
HLLH
P
V
ENI
P
E
I
I
L
Y
WKHS
T
I
F
DVGENLTVPDEF
T
V
E
E
R
QT
G
M
W
W
R
H
L
VAGGGAGAVSRTCTA
P
L
D
R
L
K
V
L
M
Q
V
-
H
A------S-------RS------NN-------M-----GIV
G
G
F
T
Q
M
I
R
EGGARSLWRGNG
I
N
V
L
K
IA
P
E
S
A
I
K
F
M
A
Y
E
Q
I
K
R
L
V-----GS
D
Q
E
-----
T
L
R
---
I
H
E
R
L
V
A
G
S
L
-----
A
G
A
I
A
QSSIY
P
M
E
V
L
K
T
R
M
A
L
-----
R
KTG-----QYS
G
M
L
D
C
A
R
R
I
L
A
R
E
G
V
A
A
F
Y
KGYVP
N
M
LGIIPYAG
I
D
L
A
V
Y
E
T
L
K
N
A
W
L
Q
H
YAVNSADP
G
V
F
V
L
L
ACGT
M
S
S
T
C
G
Q
L
A
SY
P
L
A
L
V
R
T
R
M
Q
A
QASIE--GAPE
V
--
T
M
S
S
L
--
F
K
H
I
L
RTEG
A
F
G
L
Y
RGLA
P
N
F
M
K
V
IPA
V
S
I
S
Y
V
V
YE
N
L
K
I
T
L
GVQSR
48
Fugue
86.13
27%
-65
* C2 *
1OKC
10
ADT1_BOVIN
A:
[2-293]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
Q
A
L
S
F
L
K
D
F
L
A
G
G
V
A
A
A
I
S
K
T
A
V
A
P
I
E
R
V
K
L
L
L
Q
V
-
Q
H
ASKQIS
A
-------
E
K
------
Q
Y
-------
K
-----
G
I
I
D
C
V
V
R
I
P
K
E
Q
G
F
L
S
F
W
R
G
N
L
A
N
V
I
R
Y
F
P
T
Q
A
L
N
F
A
F
K
D
K
Y
K
Q
I
F
L
GGVD
R
H
K
Q
F
-----
W
R
Y
---
F
A
G
N
L
A
S
G
G
A
-----
A
G
A
T
S
L
C
F
V
Y
P
L
D
F
A
R
T
R
L
A
A
DVGKG
A
A
Q
R
-----
E
F
T
G
L
G
N
C
I
T
K
I
F
K
S
D
G
L
R
G
L
Y
Q
G
F
N
V
S
V
Q
G
I
I
I
Y
R
A
A
Y
F
G
V
Y
D
T
A
K
G
M
L
P
D
-----
P
K
N
V
H
I
I
V
S
W
M
I
A
Q
T
V
T
A
V
A
G
L
V
S
Y
P
F
D
T
V
R
R
R
M
M
M
Q
S
G
R
K
--
G
A
D
I
M
YT
G
T
V
D
C
--
W
R
K
I
A
K
D
E
G
P
K
A
F
F
K
G
A
W
S
N
V
L
R
G
M
G
G
-
A
F
V
L
V
L
Y
D
E
I
---------
27
HHSearch
84.27
26%
-55
- C2 -
1OKC
10
ADT1_BOVIN
A:
[3-293]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
A
L
S
F
L
K
D
F
L
A
G
G
V
A
A
A
I
S
K
T
A
V
A
P
I
E
R
V
K
L
L
L
Q
V
-
Q
H
------
A
-------
S
K
QISAEK
Q
Y
-------
K
-----
G
I
I
D
C
V
V
R
I
P
K
E
Q
G
F
L
S
F
W
R
G
N
L
A
N
V
I
R
Y
F
P
T
Q
A
L
N
F
A
F
K
D
K
Y
K
Q
I
F
-----
L
G
G
V
D
RHKQ
F
W
R
Y
---
F
A
G
N
L
A
S
G
G
A
-----
A
G
A
T
S
L
C
F
V
Y
P
L
D
F
A
R
T
R
L
A
A
-----
D
V
G
K
GAAQR
E
F
T
G
L
G
N
C
I
T
K
I
F
K
S
D
G
L
R
G
L
Y
Q
G
F
N
V
S
V
Q
G
I
I
I
Y
R
A
A
Y
F
G
V
Y
D
T
A
K
G
M
L
P
D
P
K
-----
N
V
H
I
I
V
S
W
M
I
A
Q
T
V
T
A
V
A
G
L
V
S
Y
P
F
D
T
V
R
R
R
M
M
M
Q
S
G
R
K
GA
D
I
M
Y
T
--
G
T
V
D
C
--
W
R
K
I
A
K
D
E
G
P
K
A
F
F
K
G
A
W
S
N
V
L
R
G
M
G
-
G
A
F
V
L
V
L
Y
D
E
I
---------
7
PsiBlast_PDB
82.54
27%
-62
- C2 -
1OKC
10
ADT1_BOVIN
A:
[9-293]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
D
F
L
A
G
G
V
A
A
A
I
S
K
T
A
V
A
P
I
E
R
V
K
L
L
L
Q
V
Q
H
A
------
S
-------
K
Q
------
I
S
-------
A
EKQYK
G
I
I
D
C
V
V
R
I
P
K
E
Q
G
F
L
S
F
W
R
G
N
L
A
N
V
I
R
Y
F
P
T
Q
A
L
N
F
A
F
K
D
K
Y
K
Q
I
F
-----
L
G
G
V
D
-----
R
H
K
---
Q
F
W
R
Y
F
A
G
N
L
A
S
G
G
A
A
G
A
T
S
L
C
F
V
Y
P
L
D
F
A
R
T
R
L
A
A
DVGKG
A
A
Q
R
-----
E
F
T
G
L
G
N
C
I
T
K
I
F
K
S
D
G
L
R
G
L
Y
Q
G
F
N
V
S
V
Q
G
I
I
I
Y
R
A
A
Y
F
G
V
Y
D
T
A
K
G
M
L
P
D
P
K
N
V
H
I
----
I
V
S
W
M
I
A
Q
T
V
T
A
V
A
G
-
L
V
S
Y
P
F
D
T
V
R
R
R
M
M
M
Q
S
G
R
K
--
G
A
D
I
M
--
Y
T
G
T
V
D
C
W
R
K
I
A
K
D
E
G
P
K
A
F
F
K
G
A
W
S
N
V
L
R
G
M
G
G
A
F
V
-
L
V
L
Y
D
E
I
---------
8
PsiBlast_PDB
81.61
27%
-59
- C2 -
2C3E
4
ADT1_BOVIN
A:
[9-293]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
D
F
L
A
G
G
V
A
A
A
I
S
K
T
A
V
A
P
I
E
R
V
K
L
L
L
Q
V
Q
H
A
------
S
-------
K
Q
------
I
S
-------
A
EKQYK
G
I
I
D
C
V
V
R
I
P
K
E
Q
G
F
L
S
F
W
R
G
N
L
A
N
V
I
R
Y
F
P
T
Q
A
L
N
F
A
F
K
D
K
Y
K
Q
I
F
-----
L
G
G
V
D
-----
R
H
K
---
Q
F
W
R
Y
F
A
G
N
L
A
S
G
G
A
A
G
A
T
S
L
C
F
V
Y
P
L
D
F
A
R
T
R
L
A
A
DVGKG
A
A
Q
R
-----
E
F
T
G
L
G
N
C
I
T
K
I
F
K
S
D
G
L
R
G
L
Y
Q
G
F
N
V
S
V
Q
G
I
I
I
Y
R
A
A
Y
F
G
V
Y
D
T
A
K
G
M
L
P
D
P
K
N
V
H
I
----
I
V
S
W
M
I
A
Q
T
V
T
A
V
A
G
-
L
V
S
Y
P
F
D
T
V
R
R
R
M
M
M
Q
S
G
R
K
--
G
A
D
I
M
--
Y
T
G
T
V
D
C
W
R
K
I
A
K
D
E
G
P
K
A
F
F
K
G
A
W
S
N
V
L
R
G
M
G
G
A
F
V
-
L
V
L
Y
D
E
I
---------
5
PsiBlast_PDB
81.24
26%
-61
- C2 -
4C9Q
5
ADT3_YEAST
A:
[30-316]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
F
L
M
G
G
V
S
A
A
I
A
K
T
A
A
S
P
I
E
R
V
K
I
L
I
Q
N
-
Q
D
------
E
M
I
K
Q
GTL
D
K
------
K
Y
-------
S
-----
G
I
V
D
C
F
K
R
T
A
K
Q
E
G
L
I
S
F
W
R
G
N
T
A
N
V
I
R
Y
F
P
T
Q
A
L
N
F
A
F
K
D
K
I
K
L
M
F
-----
G
F
K
K
E
------
G
Y
G
K
W
F
A
G
N
L
A
S
G
G
A
-----
A
G
A
L
S
L
L
F
V
Y
S
L
D
F
A
R
T
R
L
A
A
DAKS-----AR---
Q
F
N
G
L
T
D
V
Y
K
K
T
L
K
S
D
G
I
A
G
L
Y
R
G
F
M
P
S
V
V
G
I
V
V
Y
R
G
L
Y
F
G
M
F
D
S
L
K
P
L
-------------
F
L
A
S
F
L
L
G
W
V
V
T
T
G
A
S
T
C
S
Y
P
L
D
T
V
R
R
R
M
M
-
M
T
S
G
Q
--
A
V
K
Y
N
--
G
A
I
D
C
--
L
K
K
I
V
A
S
E
G
V
G
S
L
F
K
G
C
G
A
N
I
L
R
S
V
A
G
A
G
V
-
I
S
M
Y
D
Q
L
Q
M
I
L
F
G
K
--
1
PsiBlast_PDB
79.04
63%
-57
- C1 -
4N5X
1
SCMC1_HUMAN
A:
[60-176]
-----------------------------------------------------------------
E
E
K
I
F
T
T
G
D
V
N
K
D
G
K
L
D
F
E
E
F
----
M
K
Y
L
K
D
---------
H
------
E
K
K
M
K
L
A
F
K
S
L
D
K
N
N
D
G
K
I
E
A
S
E
I
V
Q
S
L
Q
T
L
G
L
T
I
S
E
Q
Q
A
E
L
I
L
Q
S
I
D
V
D
G
T
M
T
V
D
W
N
E
W
R
D
Y
F
L
F
N
P
V
T
D
I
E
E
I
I
R
F
W
K
H
S
T
G
I
D
I
G
D
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
25
PsiBlast_CBE
78.66
64%
-66
- C1 -
4ZCU
1
?
B:
[51-165]
-----------------------------------------------------------------
E
E
K
I
F
T
T
G
D
V
N
K
D
G
K
L
D
F
E
E
F
----
M
K
Y
L
K
D
---------
H
------
E
K
K
M
K
L
A
F
K
S
L
D
K
N
N
D
G
K
I
E
A
S
E
I
V
Q
S
L
Q
T
L
G
L
T
I
S
E
Q
Q
A
E
L
I
L
Q
S
I
D
V
D
-
T
M
T
V
D
W
N
E
W
R
D
Y
F
L
F
N
P
V
T
D
I
E
E
I
I
R
F
W
K
H
S
T
G
I
D
I
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
78.19
64%
-57
- C1 -
4ZCU
1
?
A:
[51-165]
-----------------------------------------------------------------
E
E
K
I
F
T
T
G
D
V
N
K
D
G
K
L
D
F
E
E
F
----
M
K
Y
L
K
D
---------
H
------
E
K
K
M
K
L
A
F
K
S
L
D
K
N
N
D
G
K
I
E
A
S
E
I
V
Q
S
L
Q
T
L
G
L
T
I
S
E
Q
Q
A
E
L
I
L
Q
S
I
D
V
D
G
T
-
T
V
D
W
N
E
W
R
D
Y
F
L
F
N
P
V
T
D
I
E
E
I
I
R
F
W
K
H
S
T
G
I
D
I
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
76.67
64%
-58
- C1 -
4ZCV
-
?
A:
[51-165]
-----------------------------------------------------------------
E
E
K
I
F
T
T
G
D
V
N
K
D
G
K
L
D
F
E
E
F
----
M
K
Y
L
K
D
---------
H
------
E
K
K
M
K
L
A
F
K
S
L
D
K
N
N
D
G
K
I
E
A
S
E
I
V
Q
S
L
Q
T
L
G
L
T
I
S
E
Q
Q
A
E
L
I
L
Q
S
I
D
V
D
G
T
M
T
V
D
W
N
E
W
R
D
Y
F
L
F
N
P
V
T
D
I
E
E
I
I
R
F
W
K
H
S
T
G
I
D
I
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
74.36
27%
-59
- C2 -
4C9H
5
ADT2_YEAST
A:
[26-312]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
F
L
M
G
G
V
S
A
A
V
A
K
T
A
A
S
P
I
E
R
V
K
L
L
I
Q
N
-
Q
D
------
E
-------
M
L
------
K
Q
GTLDRKY
A
-----
G
I
L
D
C
F
K
R
T
A
T
Q
E
G
V
I
S
F
W
R
G
N
T
A
N
V
I
R
Y
F
P
T
Q
A
L
N
F
A
F
K
D
K
I
K
A
M
F
-----
G
F
K
K
E
EG
Y
--
A
K
W
---
F
A
G
N
L
A
S
G
G
A
-----
A
G
A
L
S
L
L
F
V
Y
S
L
D
Y
A
R
T
R
L
A
A
DS-------AR---
Q
F
N
G
L
I
D
V
Y
K
K
T
L
K
S
D
G
V
A
G
L
Y
R
G
F
L
P
S
V
V
G
I
V
V
Y
R
G
L
Y
F
G
M
Y
D
S
L
K
------------
L
A
S
F
L
L
G
W
V
V
T
T
G
A
S
T
C
----
S
Y
P
L
D
T
V
R
R
R
M
M
M
T
S
G
Q
A
--
V
K
Y
D
G
--
A
F
D
C
L
---
R
K
I
V
A
A
E
G
V
G
S
L
F
K
G
C
G
A
N
I
L
R
G
V
A
G
A
G
V
-
I
S
M
Y
D
Q
L
Q
M
I
L
F
G
K
K
F
4
PsiBlast_PDB
73.44
26%
-56
- C2 -
4C9J
4
ADT3_YEAST
A:
[30-316]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
F
L
M
G
G
V
S
A
A
I
A
K
T
A
A
S
P
I
E
R
V
K
I
L
I
Q
N
-
Q
D
------
E
M
I
K
Q
GTL
D
K
------
K
Y
-------
S
-----
G
I
V
D
C
F
K
R
T
A
K
Q
E
G
L
I
S
F
W
R
G
N
T
A
N
V
I
R
Y
F
P
T
Q
A
L
N
F
A
F
K
D
K
I
K
L
M
F
-----
G
F
K
K
E
-----
E
G
Y
G
K
W
F
A
G
N
L
A
S
G
G
A
-----
A
G
A
L
S
L
L
F
V
Y
S
L
D
F
A
R
T
R
L
A
A
DAKS-----AR---
Q
F
N
G
L
T
D
V
Y
K
K
T
L
K
S
D
G
I
A
G
L
Y
R
G
F
M
P
S
V
V
G
I
V
V
Y
R
G
L
Y
F
G
M
F
D
S
L
K
-------------------
F
L
L
G
W
V
V
T
T
G
A
S
T
C
S
Y
P
L
D
T
V
R
R
R
M
M
-
M
T
S
G
Q
--
A
V
K
Y
N
--
G
A
I
D
C
--
L
K
K
I
V
A
S
E
G
V
G
S
L
F
K
G
C
G
A
N
I
L
R
S
V
A
G
A
G
V
-
I
S
M
Y
D
Q
L
Q
M
I
L
F
G
K
K
F
20
PsiBlast_PDB
70.48
29%
-40
- C1 -
4TNC
-
?
A:
[7-154]
--------------
Q
A
E
A
R
A
F
L
S
E
E
M
I
A
E
F
K
A
A
F
D
M
F
DADG
G
G
D
I
S
T
K
E
L
G
T
V
M
R
M
L
G
Q
N
P
T
K
E
E
L
D
A
I
I
E
E
V
D
E
D
G
S
G
T
I
D
F
E
E
F
L
V
M
M
V
R
Q
M
K
E
---------
D
A
K
G
K
S
-
E
E
E
L
A
D
C
F
R
I
F
D
K
N
A
D
G
F
I
D
I
E
E
L
G
E
I
L
R
A
T
G
E
H
V
T
E
E
D
I
E
D
L
M
K
D
S
D
K
N
N
D
G
R
I
D
F
D
E
F
L
K
M
M
E
G
V
Q
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
PsiBlast_PDB
68.50
29%
-41
- C1 -
1NCX
-
TNNC2_CHICK
A:
[7-154]
--------------
Q
A
E
A
R
A
F
L
S
E
E
M
I
A
E
F
K
A
A
F
D
M
F
D
ADG
G
G
D
I
S
T
K
E
L
G
T
V
M
R
M
L
G
Q
N
P
T
K
E
E
L
D
A
I
I
E
E
V
D
E
D
G
S
G
T
I
D
F
E
E
F
L
V
M
M
V
R
Q
M
K
E
---------
D
A
K
G
K
S
-
E
E
E
L
A
N
C
F
R
I
F
D
K
N
A
D
G
F
I
D
I
E
E
L
G
E
I
L
R
A
T
G
E
H
V
T
E
E
D
I
E
D
L
M
K
D
S
D
K
N
N
D
G
R
I
D
F
D
E
F
L
K
M
M
E
G
V
Q
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
PsiBlast_PDB
68.43
29%
-36
- C1 -
1NCZ
-
TNNC2_CHICK
A:
[7-154]
--------------
Q
A
E
A
R
A
F
L
S
E
E
M
I
A
E
F
K
A
A
F
D
M
F
D
ADG
G
G
D
I
S
T
K
E
L
G
T
V
M
R
M
L
G
Q
N
P
T
K
E
E
L
D
A
I
I
E
E
V
D
E
D
G
S
G
T
I
D
F
E
E
F
L
V
M
M
V
R
Q
M
K
E
---------
D
A
K
G
K
S
-
E
E
E
L
A
N
C
F
R
I
F
D
K
N
A
D
G
F
I
D
I
E
E
L
G
E
I
L
R
A
T
G
E
H
V
T
E
E
D
I
E
D
L
M
K
D
S
D
K
N
N
D
G
R
I
D
F
D
E
F
L
K
M
M
E
G
V
Q
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
PsiBlast_PDB
67.95
29%
-37
* C1 *
1TOP
-
TNNC2_CHICK
A:
[7-154]
--------------
Q
A
E
A
R
A
F
L
S
E
E
M
I
A
E
F
K
A
A
F
D
M
F
D
ADG
G
G
D
I
S
T
K
E
L
G
T
V
M
R
M
L
G
Q
N
P
T
K
E
E
L
D
A
I
I
E
E
V
D
E
D
G
S
G
T
I
D
F
E
E
F
L
V
M
M
V
R
Q
M
K
E
---------
D
A
K
G
K
S
-
E
E
E
L
A
N
C
F
R
I
F
D
K
N
A
D
G
F
I
D
I
E
E
L
G
E
I
L
R
A
T
G
E
H
V
T
E
E
D
I
E
D
L
M
K
D
S
D
K
N
N
D
G
R
I
D
F
D
E
F
L
K
M
M
E
G
V
Q
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
PsiBlast_PDB
67.84
29%
-39
- C1 -
1NCY
-
TNNC2_CHICK
A:
[7-154]
--------------
Q
A
E
A
R
A
F
L
S
E
E
M
I
A
E
F
K
A
A
F
D
M
F
D
ADG
G
G
D
I
S
T
K
E
L
G
T
V
M
R
M
L
G
Q
N
P
T
K
E
E
L
D
A
I
I
E
E
V
D
E
D
G
S
G
T
I
D
F
E
E
F
L
V
M
M
V
R
Q
M
K
E
---------
D
A
K
G
K
S
-
E
E
E
L
A
N
C
F
R
I
F
D
K
N
A
D
G
F
I
D
I
E
E
L
G
E
I
L
R
A
T
G
E
H
V
T
E
E
D
I
E
D
L
M
K
D
S
D
K
N
N
D
G
R
I
D
F
D
E
F
L
K
M
M
E
G
V
Q
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
67.41
29%
-30
- C1 -
5TNC
-
TNNC2_MELGA
A:
[7-154]
--------------
Q
A
E
A
R
A
F
L
S
E
E
M
I
A
E
F
K
A
A
F
D
M
FDADG
G
G
D
I
S
T
K
E
L
G
T
V
M
R
M
L
G
Q
N
P
T
K
E
E
L
D
A
I
I
E
E
V
D
E
D
G
S
G
T
I
D
F
E
E
F
L
V
M
M
V
R
Q
M
K
E
---------
D
A
K
G
K
S
-
E
E
E
L
E
D
C
F
R
I
F
D
K
N
A
D
G
F
I
D
I
E
E
L
G
E
I
L
R
A
T
G
E
H
V
T
E
E
D
I
E
D
L
M
K
D
S
D
K
N
N
D
G
R
I
D
F
D
E
F
L
K
M
M
E
G
V
Q
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
PsiBlast_PDB
63.49
29%
-15
- C1 -
1YTZ
1
?
C:
[7-154]
--------------
Q
A
E
A
R
A
F
L
S
E
E
M
I
A
E
F
K
A
A
F
D
M
FDADG
G
G
D
I
S
T
K
E
L
G
T
V
MRMLGQNPT
K
E
E
L
D
A
I
I
E
E
V
D
E
D
G
S
G
T
I
D
F
E
E
F
LVMM
V
R
Q
M
K
E
---------
D
AKGKS-
E
E
E
L
A
N
C
F
R
I
F
D
K
N
A
D
G
F
I
D
I
E
E
L
G
E
I
L
R
A
T
G
E
H
V
T
E
E
D
I
E
D
L
M
K
D
S
D
K
N
N
D
G
R
I
D
F
D
E
F
L
K
M
M
E
G
V
Q
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
44
HHSearch
62.00
27%
-32
- C1 -
1TOP
-
TNNC2_CHICK
A:
[16-159]
-------
E
E
M
I
A
E
F
K
A
A
F
D
M
F
D
A
D
--
G
G
G
D
I
S
T
K
E
L
-----
G
T
V
M
R
M
L
G
Q
N
P
T
---------
K
E
E
L
D
A
I
I
E
E
V
D
E
D
G
S
G
T
I
D
F
E
E
F
----
L
V
M
M
V
R
Q
M
K
E
D
A
K
G
K
S
------
E
E
E
L
A
N
C
F
R
I
F
D
K
N
A
D
G
F
I
D
I
E
E
L
G
E
I
L
R
A
T
G
E
H
V
T
E
E
D
I
E
D
L
M
K
D
S
D
K
N
N
D
G
R
I
D
F
D
E
F
L
K
M
M
E
G
V
Q
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
39
HHSearch
59.11
16%
-25
- C1 -
2OBH
2
CETN2_HUMAN
A:
[3-142]
--------
E
Q
K
Q
E
I
R
E
A
F
D
L
F
D
A
D
--
G
T
G
T
I
D
V
K
E
L
-----
K
V
A
M
R
A
L
G
F
E
P
K
---------
K
E
E
I
K
K
M
I
S
E
I
D
K
E
G
T
G
K
M
N
F
G
D
F
----
L
T
V
M
T
Q
---------
K
M
S
E
K
D
T
K
E
E
I
L
K
A
F
K
L
F
D
D
D
E
T
G
K
I
S
F
K
N
L
K
R
V
A
K
E
L
G
E
N
L
T
D
E
E
L
Q
E
M
I
D
E
A
D
R
D
G
D
G
E
V
S
E
Q
E
F
L
R
I
M
K
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------