@TOME V2.2
(Nov 2016)
Ref.
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : SL9A1_HUMAN: (2015-12-12 )
MVLRSGICGLSPHRIFPSLLVVVALVGLLPVLRSHGLQLSPTASTIRSSEPPRERSIGDVTTAPPEVTPESRPVNHSVTDHGMKPRKAFPVLGIDYTHVRTPFEISLWILLACLMKIGFHVIPTISSIVPESCLLIVVGLLVGGLIKGVGETPPFLQSDVFFLFLLPPIILDAGYFLPLRQFTENLGTILIFAVVGTLWNAFFLGGLMYAVCLVGGEQINNIGLLDNLLFGSIISAVDPVAVLAVFEEIHINELLHILVFGESLLNDAVTVVLYHLFEEFANYEHVGIVDIFLGFLSFFVVALGGVLVGVVYGVIAAFTSRFTSHIRVIEPLFVFLYSYMAYLSAELFHLSGIMALIASGVVMRPYVEANISHKSHTTIKYFLKMWSSVSETLIFIFLGVSTVAGSHHWNWTFVISTLLFCLIARVLGVLGLTWFINKFRIVKLTPKDQFIIAYGGLRGAIAFSLGYLLDKKHFPMCDLFLTAIITVIFFTVFVQGMTIRPLVDLLAVKKKQETKRSINEEIHTQFLDHLLTGIEDICGHYGHHHWKDKLNRFNKKYVKKCLIAGERSKEPQLIAFYHKMEMKQAIELVESGGMGKIPSAVSTVSMQNIHPKSLPSERILPALSKDKEEEIRKILRNNLQKTRQRLRSYNRHTLVADPYEEAWNQMLLRRQKARQLEQKINNYLTVPAHKLDSPTMSRARIGSDPLAYEPKEDLPVITIDPASPQSPESVDLVNEELKGKVLGLSRDPAKVAEEDEDDDGGIMMRSKETSSPGTDDVFTPAPSDSPSSQRIQRCLSDPGPHPEPGEGEPFFPKGQ
Atome Classification :
(20 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120......--.130.......140.......150.......160.......170.......180....---...---190.......200.......210.......220.....-----..230.......240.......250.........260.......----270.......280.......290.......300.......310.......320....---...330.......340.....------..350-----.......360.......370.......380.......390..-.....400.......-410.......420----.......-430.......440---........450...-....----460.......470---------.......-------------.480.......490.......500.......510.......520.......530.......540.......550.......560.......570.......580.......590.......600.......610.---......620.......630...-----....640.......650........660.......670.......680.......690.....------..700.......710.......720.-.....-.-730.......740.......750.......760.......770.......780.......790.......800.......810...
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MVLRSGICGL
S
P
H
R
I
F
P
S
L
L
V
V
V
A
L
V
G
L
L
P
V
L
R
SHG
L
Q
LSP
T
A
S
TIRSSEPPRERSIGDVTTAPPEVTPESRPVNHSVTDHGMKPRKAF
P
V
LGI
D
Y
T
HVRTP
F
E
I
S
L
W
I
L
L
A
C
L
M
K
IG
F
H
V
I
P
T
I
S
S
I--V
P
E
S
C
L
L
I
V
V
G
L
L
V
G
G
L
I
KGVGETPPFLQS
D
V
F
F
L
F
LL
P
P
I
ILDAGY
F
L
P
L
R
Q
F
T
E
N
L
---
G
T
I
---
L
I
F
A
V
V
G
T
L
W
N
A
F
F
L
G
G
L
M
Y
A
V
C
LVGGEQINN
I
G
L
L
D
N
-----
L
L
F
G
S
I
I
S
AV
D
P
V
A
V
L
A
V
F
E
E
I
H
--
I
N
E
L
L
H
I
L
V
F
G
E
S
L
L
N
D
A
V
----
T
V
V
L
Y
H
L
F
E
E
FANYEH
V
G
I
V
D
I
F
L
G
F
L
S
F
F
V
V
A
L
G
G
V
L
V
G
V
V
Y
G
V
I
A
A
F
T
S
R
F
T
S
H
I
---
R
V
I
E
P
L
F
V
F
L
Y
S
Y
M
A
Y
L
S
A
E
L
------
F
H
L
S
G
-----
I
M
A
L
I
ASG
V
V
MRP
Y
V
E
ANISHKS
H
T
T
I
K
Y
F
L
K
M
W
S
S
V
S
E
T
L
I
-
F
I
F
L
G
V
S
TVAGSHHW-
N
W
T
F
V
I
S
T
L
L
F
C
L
----
I
A
R
V
L
G
V
-
L
G
L
T
W
F
IN
K
F
R
I
----
V
K
LTPKD
Q
F
I
I
A
YG-GL
R
G
----
A
I
A
F
S
L
G
Y
L
LDK----------KHF
P
M
C
D
-------------
L
F
L
T
A
I
I
T
V
I
F
F
T
V
F
VQGM
T
I
R
P
L
V
D
L
L
A
V
K
K
K
Q
E
T
K
R
S
I
N
E
E
I
H
T
Q
F
L
D
H
L
L
T
G
I
E
D
I
C
G
HYG
H
H
H
W
K
D
K
L
N
R
F
N
K
K
Y
V
K
K
C
L
IAGERSKEP
Q
L
I
A
F
Y
H
K
M
E
M
K
Q
A
I
E
L
V
ESGGMGKIP
S
A
V
S
T
V
S
MQNIHPKS---L
P
S
E
RILPALSKD
K
E
E
E
I
R
K
I
L
-----
R
N
N
L
Q
K
T
R
Q
R
L
R
SYNR-H
T
L
VAD
P
Y
E
E
A
W
N
Q
M
L
L
R
R
Q
K
A
R
Q
L
E
Q
K
I
N
N
Y
L
TVPAHKLDSP
T
M
S
------RARIGSDPLAYEPKEDL
P
V
I
T
IDPAS-PQSPE-
S
-
V
D
L
V
N
E
ELK
G
K
V
LGLSR
D
P
A
K
VAEEDEDDDG
G
I
M
M
RSKETSSPGTDDVFTPAPSDS
P
S
S
Q
R
I
Q
R
C
LSDPGPHPEPGEGEPFFPKGQ
40
Fugue
95.11
20%
-149
- C4 -
4CZB
-
NAH1_METJA
A:
[1-415]
------------------------------------------------------------------------------------------------------
M
E
L
M
M
A
I
G
Y
L
G
L
A
L
V
L
G
S
L
V
A
K
I
A
E
K
L
K
I
P
D
I
P
L
L
L
L
L
G
L
I
I
G
P
F
L
Q
I
I
P
S
D
S
A
M
E
I
F
E
Y
A
G
P
I
G
L
I
F
I
L
L
G
G
A
F
T
M
R
I
S
L
L
K
R
V
I
---
K
T
V
---
V
R
L
D
T
-----------
I
T
F
L
I
T
L
L
I
S
G
F
I
F
N
M
V
L
N
L
P
Y
TS
P
V
G
Y
L
F
G
A
I
T
A
A
T
D
P
A
T
L
I
P
V
F
S
R
V
R
--
T
N
P
E
V
A
I
T
L
E
A
E
S
I
F
N
D
P
L
----
G
I
V
S
T
S
V
I
L
G
L
F
G
L
F
S
S
S
N
P
L
I
D
L
I
T
L
A
G
G
A
I
V
V
G
L
L
L
A
K
I
Y
E
K
I
I
I
H
C
D
F
H
E
Y
V
A
P
---
L
V
L
G
G
A
M
L
L
L
Y
V
G
D
D
L
L
P
S
I
C
G-----
Y
G
F
S
G
-----
Y
M
A
V
A
I
M
G
L
Y
L
G
D
A
L
F
R
A
D
D
-
I
D
Y
K
Y
I
V
S
F
C
D
D
L
S
L
L
A
R
V
F
I
-
F
V
F
L
G
A
C
I
---
K
L
S
M
-
L
E
N
Y
F
I
P
G
L
L
V
A
L
----
G
S
I
F
L
-
A
-
R
P
L
G
V
F
L
G
-
L
I
G
----
S
K
H
S
F
K
E
K
L
Y
F
A
L
E
-
G
P
R
G
----
V
V
P
A
A
L
A
V
T
V
G
I
----------
E
I
L
K
N
A
D
KIPA
S
I
T
K
Y
IT
P
T
D
I
A
G
T
I
I
I
G
T
F
M
T
I
L
L
S
V
I
L
E
A
S
W
A
G
M
L
A
L
K
L
L
G
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
74.65
25%
-136
- C4 -
4CZB
-
NAH1_METJA
A:
[123-415]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
F
G
A
I
T
A
A
T
D
P
A
T
L
I
P
V
F
S
R
V
R
--
T
N
P
E
V
A
I
T
L
E
A
E
S
I
F
N
D
P
L
G
I
V
S
T
S
V
I
L
G
L
F
G
L
F
S
S
S
N
P
L
---------
I
D
L
I
T
L
A
G
G
A
I
V
V
G
L
L
---
L
A
K
I
Y
E
K
I
I
I
H
C
DFH
E
Y
V
A
P
L
V
L
G
G
A
M
L
L
L
Y
V
G
D
D
L
L
P
S
I
CG
Y
G
F
S
G
Y
M
A
V
A
I
M
G
L
Y
L
G
D
A
L
F
R
---
A
D
D
I
D
Y
K
Y
---
I
V
S
F
C
D
D
L
S
L
L
A
R
V
F
I
-
F
V
F
L
G
-
A
C
I
K
L
S
M
L
E
-
N
Y
--
F
I
P
G
L
L
V
A
L
G
S
I
F
L
A
R
P
L
G
V
F
L
G
L
I
G
S
K
H
S
F
-----------
K
E
K
L
Y
F
A
L
E
-
G
P
R
G
V
V
P
A
A
L
A
V
T
V
G
I
E
I
L
K
N
ADKIPA
S
I
T
K
Y
I
T
P
T
D
-------------
I
A
G
T
I
I
I
G
T
-
F
M
T
I
L
L
S
V
I
L
E
A
S
W
A
G
M
L
A
L
K
L
L
G
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
PsiBlast_PDB
74.19
25%
-127
- C4 -
4D0A
-
NAH1_METJA
B:
[123-419]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
F
G
A
I
T
A
A
T
D
P
A
T
L
I
P
V
F
S
R
V
R
--
T
N
P
E
V
A
I
T
L
E
A
E
S
I
F
N
D
P
L
GIVS
T
S
V
I
L
G
L
F
G
L
F
S
S
S
N
P
L
---------
I
D
L
I
T
L
A
G
G
A
I
V
V
G
L
L
---
L
A
K
I
Y
E
K
I
I
I
H
C
DFH
E
Y
V
A
P
L
V
L
G
G
A
M
L
L
L
Y
V
G
D
D
L
LPSICG
Y
G
F
S
G
YMAVA
I
M
G
L
Y
L
G
D
A
L
F
R
---
A
D
D
I
D
Y
K
Y
---
I
V
S
F
C
D
D
L
S
L
L
A
R
V
F
I
-
F
V
F
L
G
-
A
C
I
K
L
S
M
L
E
-
N
Y
--
F
I
P
G
L
L
V
A
L
GSIF
L
A
R
P
L
G
V
F
L
G
L
I
G
S
K
H
S
F
-----------
K
E
K
L
Y
F
A
L
E
-
G
P
R
G
VVPA
A
L
A
V
T
V
G
I
E
I
L
K
NADKIPASIT
K
Y
I
T
P
T
D
-------------
I
A
G
T
I
I
I
G
T
-
F
M
T
I
L
L
S
V
I
L
E
A
S
W
A
G
M
L
A
L
K
L
L
G
E
Y
K
P
K
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
HHSearch
55.10
100%
162
- C4 -
2YGG
4
A:
[3-66]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
L
S
K
D
K
E
E
E
I
R
K
I
L
-----
R
N
N
L
Q
K
T
R
Q
R
L
R
S
Y
N
R
-
H
T
L
V
A
D
P
Y
E
E
A
W
N
Q
M
L
L
R
R
Q
K
A
R
Q
L
E
Q
K
I
N
N
Y
L
T
-------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
55.10
100%
162
- C4 -
2YGG
4
A:
[3-66]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
L
S
K
D
K
E
E
E
I
R
K
I
L
-----
R
N
N
L
Q
K
T
R
Q
R
L
R
S
Y
N
R
-
H
T
L
V
A
D
P
Y
E
E
A
W
N
Q
M
L
L
R
R
Q
K
A
R
Q
L
E
Q
K
I
N
N
Y
L
T
-------------------------------------------------------------------------------------------------------------------------------------------
32
Fugue
54.96
96%
161
- C4 -
2YGG
4
A:
[1-66]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
F
A
L
S
K
D
K
E
E
E
I
R
K
I
L
-----
R
N
N
L
Q
K
T
R
Q
R
L
R
S
Y
N
R
-
H
T
L
V
A
D
P
Y
E
E
A
W
N
Q
M
L
L
R
R
Q
K
A
R
Q
L
E
Q
K
I
N
N
Y
L
T
-------------------------------------------------------------------------------------------------------------------------------------------
22
HHSearch
52.70
13%
-126
- C4 -
1ZCD
-
NHAA_ECOLI
A:
[61-351]
----------------------------------------------------------------------------------------------------------------------------------------------------------------
L
W
I
N
D
A
L
M
A
V
F
F
L
L
V
G
L
E
V
K
R
E
L
M
Q
G
S
L
ASL
R
Q
A
A
F
P
V
I
A
A
I
G
G
M
I
V
P
A
L
L
Y
L
A
F
N
Y
-----------
A
-
D
P
I
T
R
-----
E
G
W
A
I
-
P
A
A
T
D
I
A
F
A
L
G
V
L
A
L
L
G
SR
V
P
L
A
L
K
I
F
L
M
A
L
A
I
I
D
D
L
G
----
A
I
I
I
I
A
L
F
Y
T
N
D
L
S
-------
M
A
-------
S
L
-
G
V
-
A
A
V
A
I
A
V
L
A
V
L
N
----
L
C
G
A
----
R
R
T
G
V
Y
--
I
L
V
G
V
V
L
W
T
A
V
L
K
------
S
G
V
H
A
-----
T
L
A
G
V
I
V
G
F
F
I
P
L
K
E
K
H
G
R
S
-
P
A
K
R
L
E
H
V
L
H
P
W
V
A
Y
L
I
L
P
L
F
A
F
A
N
A
G
V
S
L
Q
G
V
T
L
D
G
L
T
S
I
L
P
L
G
I
I
A
G
L
L
----
I
G
K
P
L
G
I
-
S
L
F
C
W
L
A
L
R
L
K
L
AHLP
E
G
T
T
Y
Q
Q
I
M
V
V
G
I
L
C
G
I
G
F
----
T
M
S
I
F
I
A
S
L
A
F
G
----------
S
V
D
P
E
L
I
-------------
N
W
A
K
L
G
I
L
V
G
S
I
S
S
A
V
I
G
Y
S
W
L
R
V
R
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
44.26
26%
-96
- C4 -
4CZ8
2
?
A:
[34-165]
---------------------------------------------------------------------------------------------------------------------------------------
I
F
I
L
T
G
L
V
I
G
P
L
L
K
L
I
P
R
D
L
A
H
E
I
F
D
F
V
R
V
F
G
L
V
I
I
L
F
T
E
G
H
N
L
S
W
R
L
L
K
K
N
M
---
P
T
I
---
V
T
L
D
T
I
G
L
I
L
T
A
L
-
I
A
G
F
I
F
K
V
V
F
-------
N
S
S
F
L
L
G
-----
F
L
F
G
A
I
I
G
A
T
D
P
A
T
L
I
P
L
F
R
Q
Y
R
--
V
K
Q
D
I
E
T
V
I
V
T
E
S
I
F
N
D
P
L
----
G
I
V
L
T
L
I
A
I
S
M
L
V
P
G
Y
G
G
G
I
F
S
T
L
S
E
K
L
G
I
Y
A
G
G
V
I
Y
F
L
Y
N
V
S
V
S
I
S
L
G
I
F
L
G
I
L
G
Y
---
K
F
I
K
R
T
G
I
F
D
F
P
E
I
E
A
F
S
L
S
L
------
A
F
L
G
F
-----
F
I
G
E
R
L
D
A
S
G
Y
L
V
A
T
V
T
G
I
V
L
G
N
Y
K
L
L
K
P
R
E
N
I
R
I
L
K
R
L
Q
R
A
-
I
E
K
E
V
H
F
N
D
T
L
A
A
L
A
-
T
I
F
I
F
V
L
L
G
A
E
M
N
----
L
E
V
I
W
S
N
-
L
G
K
G
L
L
V
A
L
G
V
M
----
I
L
A
R
P
L
A
T
L
P
L
L
K
W
-
W
N
F
R
----
E
Y
L
F
I
A
L
E
G
P
R
G
----------
V
V
P
S
A
L
A
-------------
S
L
P
L
S
L
A
L
K
Y
K
S
P
L
L
T
V
H
W
G
E
I
I
M
A
T
V
V
I
T
V
L
T
S
V
I
V
E
T
L
W
I
P
I
L
K
D
K
L
D
V
G
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
44.06
26%
-87
- C4 -
4CZ9
-
?
A:
[34-165]
---------------------------------------------------------------------------------------------------------------------------------------
I
F
I
L
T
G
L
V
I
G
P
L
L
K
L
I
P
R
D
L
A
H
E
I
F
D
F
V
R
V
F
G
L
V
I
I
L
F
T
E
G
H
N
L
S
W
R
L
L
K
K
N
M
---
P
T
I
---
V
T
L
D
T
I
G
L
I
L
T
A
L
-
I
A
G
F
I
F
K
V
V
F
-------
N
S
S
F
L
L
G
-----
F
L
F
G
A
I
I
G
A
T
D
P
A
T
L
I
P
L
F
R
Q
Y
R
--
V
K
Q
D
I
E
T
V
I
V
T
E
S
I
F
N
D
P
L
----
G
I
V
L
T
L
I
A
I
S
M
L
V
P
G
Y
G
G
G
I
F
S
T
L
S
E
K
L
G
I
Y
A
G
G
V
I
Y
F
L
Y
N
V
S
V
S
I
S
L
G
I
F
L
G
I
L
G
Y
---
K
F
I
K
R
T
G
I
F
D
F
P
E
I
E
A
F
S
L
S
L
------
A
F
L
G
F
-----
F
I
G
E
R
L
D
A
S
G
Y
L
V
A
T
V
T
G
I
V
L
G
N
Y
K
L
L
K
P
R
E
N
I
R
I
L
K
R
L
Q
R
A
-
I
E
K
E
V
H
F
N
D
T
L
A
A
L
A
-
T
I
F
I
F
V
L
L
G
A
E
M
N
----
L
E
V
I
W
S
N
-
L
G
K
G
L
L
V
A
L
G
V
M
----
I
L
A
R
P
L
A
T
L
P
L
L
K
W
-
W
N
F
R
----
E
Y
L
F
I
A
L
E
G
P
R
G
----------
V
V
P
S
A
L
A
-------------
S
L
P
L
S
L
A
L
K
Y
K
S
P
L
L
T
V
H
W
G
E
I
I
M
A
T
V
V
I
T
V
L
T
S
V
I
V
E
T
L
W
I
P
I
L
K
D
K
L
D
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
43.85
26%
-94
- C4 -
4CZA
1
?
A:
[34-165]
---------------------------------------------------------------------------------------------------------------------------------------
I
F
I
L
T
G
L
V
I
G
P
L
L
K
L
I
P
R
D
L
A
H
E
I
F
D
F
V
R
V
F
G
L
V
I
I
L
F
T
E
G
H
N
L
S
W
R
L
L
K
K
N
M
---
P
T
I
---
V
T
L
D
T
I
G
L
I
L
T
A
L
-
I
A
G
F
I
F
K
V
V
F
-------
N
S
S
F
L
L
G
-----
F
L
F
G
A
I
I
G
A
T
D
P
A
T
L
I
P
L
F
R
Q
Y
R
--
V
K
Q
D
I
E
T
V
I
V
T
E
S
I
F
N
D
P
L
----
G
I
V
L
T
L
I
A
I
S
M
L
V
P
G
Y
G
G
G
I
F
S
T
L
S
E
K
L
G
I
Y
A
G
G
V
I
Y
F
L
Y
N
V
S
V
S
I
S
L
G
I
F
L
G
I
L
G
Y
---
K
F
I
K
R
T
G
I
F
D
F
P
E
I
E
A
F
S
L
S
L
------
A
F
L
G
F
-----
F
I
G
E
R
L
D
A
S
G
Y
L
V
A
T
V
T
G
I
V
L
G
N
Y
K
L
L
K
P
R
E
N
I
R
I
L
K
R
L
Q
R
A
-
I
E
K
E
V
H
F
N
D
T
L
A
A
L
A
-
T
I
F
I
F
V
L
L
G
A
E
M
N
----
L
E
V
I
W
S
N
-
L
G
K
G
L
L
V
A
L
G
V
M
----
I
L
A
R
P
L
A
T
L
P
L
L
K
W
-
W
N
F
R
----
E
Y
L
F
I
A
L
E
G
P
R
G
----------
V
V
P
S
A
L
A
-------------
S
L
P
L
S
L
A
L
K
Y
K
S
P
L
L
T
V
H
W
G
E
I
I
M
A
T
V
V
I
T
V
L
T
S
V
I
V
E
T
L
W
I
P
I
L
K
D
K
L
D
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
41
Fugue
38.45
13%
49
- C1 -
4KQT
4
?
A:
[15-183]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
Y
F
Q
G
T
H
G
P
A
L
P
G
V
C
I
F
S
S
P
R
A
V
G
S
S
---
L
V
G
K
A
V
D
A
R
L
K
T
I
I
Q
Q
V
N
A
E
L
T
-----
G
E
R
T
A
L
D
N
E
A
K
A
L
D
A
K
K
T
T
I
A
Q
D
A
L
E
Q
Q
A
A
T
L
Q
A
K
A
N
A
W
Q
R
K
G
Q
L
R
Q
K
E
V
E
A
T
E
Q
K
A
L
S
R
V
Y
Q
------
E
L
N
T
P
I
Q
Q
V
Y
Q
A
--
Q
K
C
S
V
L
L
D
R
E
A
V
M
L
A
N
P
A
M
D
I
T
D
A
V
V
A
A
L
D
A
R
I
K
T
L
T
F
D
R
E
R
L
D
Q
Q
-------------------------------------------------------------
14
PsiBlast_PDB
37.31
27%
93
- C2 -
3C9F
1
?
A:
[346-434]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
P
K
S
I
F
N
L
L
A
L
K
I
L
K
T
L
P
K
S
K
H
E
E
R
I
T
I
I
N
TGSI
R
Y
D
L
Y
K
G
P
Y
T
I
D
S
-----
K
F
I
V
S
P
F
E
N
I
W
V
N
I
T
V
P
K
S
V
A
T
K
V
A
A
K
L
N
--
D
Y
I
S
A
S
R
L
K
P
P
H
Q
Y
------
D
L
Q
V
Q
Q
E
K
L
P
K
G
Y
V
T
H
D
D
F
G
A
D
G
D
D
T
-
L
H
R
A
V
-
V
-
N
F
P
V
P
N
V
I
Q
S
V
E
I
N
D
E
V
D
S
P
V
N
L
V
F
Y
S
F
I
T
P
N
I
I
W
A
L
K
E
L
N
F
S
T
E
Q
V
P
T
P
Y
S
D
I
Y
L
G
T
L
L
N
E
F
V
A
N
N
E
------------------
33
Fugue
36.10
100%
299
- C4 -
2E30
-
B:
[1-43]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
D
L
L
A
V
K
K
K
Q
E
T
K
R
S
I
N
E
E
I
H
T
Q
F
L
D
H
L
L
T
G
I
E
D
I
C
G
H
Y
G
H
H
H
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
36.10
100%
299
- C4 -
2E30
-
B:
[1-43]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
D
L
L
A
V
K
K
K
Q
E
T
K
R
S
I
N
E
E
I
H
T
Q
F
L
D
H
L
L
T
G
I
E
D
I
C
G
H
Y
G
H
H
H
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
PsiBlast_PDB
32.13
28%
229
- C3 -
3T5T
-
?
A:
[230-297]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
P
D
A
R
I
D
R
E
A
M
T
V
E
W
RG
H
R
T
R
L
R
T
M
P
L
G
Y
S
P
------
L
T
L
-----
P
Q
L
P
E
-
G
-
I
E
E
W
A
D
G
H
R
L
V
V
H
S
G
R
T
D
P
I
K
N
A
E
R
A
V
R
A
F
V
L
A
A
R
G
G
G
L
E
K
T
R
M
L
V
R
M
N
P
N
R
L
Y
V
P
A
N
A
D
Y
V
H
R
V
E
T
A
V
A
E
A
N
A
E
L
G
S
D
T
V
R
I
D
N
D
18
PsiBlast_PDB
29.61
34%
276
- C6 -
1NTH
1
MTMB1_METBA
A:
[93-142]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
A
I
N
N
V
Q
K
E
F
V
L
G
T
G
R
D
A
V
N
V
R
K
R
S
V
G
D
K
A
K
P
I
V
Q
G
G
P
T
G
S
P
I
S
E
D
V
F
M
P
V
H
M
S
Y
A
L
E
K
E
V
D
T
I
V
N
G
V
M
T
S
V
R
G
K
S
P
I
P
K
S
P
Y
E
V
16
PsiBlast_PDB
29.15
34%
277
- C6 -
1TV3
1
MTMB1_METBA
A:
[93-142]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
A
I
N
N
V
Q
K
E
F
V
L
G
T
G
R
D
A
V
N
V
R
K
R
S
V
G
D
K
A
K
P
I
V
Q
G
G
P
T
G
S
P
I
S
E
D
V
F
M
P
V
H
M
S
Y
A
L
E
K
E
V
D
T
I
V
N
G
V
M
T
S
V
R
G
K
S
P
I
P
K
S
P
Y
E
V
17
PsiBlast_PDB
29.14
34%
280
* C6 *
1TV4
1
MTMB1_METBA
A:
[93-142]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
A
I
N
N
V
Q
K
E
F
V
L
G
T
G
R
D
A
V
N
V
R
K
R
S
V
G
D
K
A
K
P
I
V
Q
G
G
P
T
G
S
P
I
S
E
D
V
F
M
P
V
H
M
S
Y
A
L
E
K
E
V
D
T
I
V
N
G
V
M
T
S
V
R
G
K
S
P
I
P
K
S
P
Y
E
V
19
PsiBlast_PDB
28.68
34%
287
- C6 -
1L2Q
1
MTMB1_METBA
A:
[93-142]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
A
I
N
N
V
Q
K
E
F
V
L
G
T
G
R
D
A
V
N
V
R
K
R
S
V
G
D
K
A
K
P
I
V
Q
G
G
P
T
G
S
P
I
S
E
D
V
F
M
P
V
H
M
S
Y
A
L
E
K
E
V
D
T
I
V
N
G
V
M
T
S
V
R
G
K
S
P
I
P
K
S
P
Y
E
V
15
PsiBlast_PDB
28.26
34%
276
- C6 -
1TV2
1
MTMB1_METBA
A:
[93-142]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
A
I
N
N
V
Q
K
E
F
V
L
G
T
G
R
D
A
V
N
V
R
K
R
S
V
G
D
K
A
K
P
I
V
Q
G
G
P
T
G
S
P
I
S
E
D
V
F
M
P
V
H
M
S
Y
A
L
E
K
E
V
D
T
I
V
N
G
V
M
T
S
V
R
G
K
S
P
I
P
K
S
P
Y
E
V