@TOME V2.2
(Nov 2016)
Ref.
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : SL9A2_HUMAN: (2015-12-12 )
MEPLGNWRSLRAPLPPMLLLLLLQVAGPVGALAETLLNAPRAMGTSSSPPSPASVVAPGTTLFEESRLPVFTLDYPHVQIPFEITLWILLASLAKIGFHLYHKLPTIVPESCLLIMVGLLLGGIIFGVDEKSPPAMKTDVFFLYLLPPIVLDAGYFMPTRPFFENIGTIFWYAVVGTLWNSIGIGVSLFGICQIEAFGLSDITLLQNLLFGSLISAVDPVAVLAVFENIHVNEQLYILVFGESLLNDAVTVVLYNLFKSFCQMKTIETIDVFAGIANFFVVGIGGVLIGIFLGFIAAFTTRFTHNIRVIEPLFVFLYSYLSYITAEMFHLSGIMAITACAMTMNKYVEENVSQKSYTTIKYFMKMLSSVSETLIFIFMGVSTVGKNHEWNWAFVCFTLAFCLMWRALGVFVLTQVINRFRTIPLTFKDQFIIAYGGLRGAICFALVFLLPAAVFPRKKLFITAAIVVIFFTVFILGITIRPLVEFLDVKRSNKKQQAVSEEIYCRLFDHVKTGIEDVCGHWGHNFWRDKFKKFDDKYLRKLLIRENQPKSSIVSLYKKLEIKHAIEMAETGMISTVPTFASLNDCREEKIRKVTSSETDEIRELLSRNLYQIRQRTLSYNRHSLTADTSERQAKEILIRRRHSLRESIRKDSSLNREHRASTSTSRYLSLPKNTKLPEKLQKRRTISIADGNSSDSDADAGTTVLNLQPRARRFLPEQFSKKSPQSYKMEWKNEVDVDSGRDMPSTPPTPHSREKGTQTSGLLQQPLLSKDQSGSEREDSLTEGIPPKPPPRLVWRASEPGSRKARFGSEKP
Atome Classification :
(20 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140......----.150.......160....---...---170.......180.......190.......200.....-----..210.......220.......230.........240.......----250.......----------260.......270.......280..-.....290.......300.......310--.........320.....------..330.......340.....----..350-----.......360--........370..-.....380.......-390.--......400.......410.......420--....----.....430...-....440.......450.....------------..460.......470.......480.......490.......500.......510.......520.......530.......540.......550.......560.......570.......580.......590.......600.......610.......620.......630.......640.......650.......660.......670.......680.......690.......700.......710.......720.......730.......740.......750-.........760.......770.......780.......790.......800.......810
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MEPLGN
W
R
SLRAP
L
P
P
M
L
L
L
L
L
L
Q
VAG
P
V
G
A
L
A
E
T
L
LNAPRAMGTSSSPPSPASVVAPGTTLFEESRL
P
V
F
T
LDYP
H
V
Q
I
P
F
E
I
T
L
W
I
L
L
A
S
L
A
K
I
G
F
H
L
Y
H
K
L
P
TIV
P
E
S
C
L
L
I
M
V
G
L
L
L
G
G
I
I
F
GVDEKSPPAMK
T
D
V
F
F
L
Y
LL
P
P
----
I
VLDAGYFMPT
R
P
F
F
E
N
I
---
G
T
I
---
F
W
Y
A
V
V
G
T
L
W
N
S
IGI
G
V
S
L
F
G
I
C
Q
I
E
AFGL
S
D
I
T
L
L
Q
N
-----
L
L
F
G
S
L
I
S
AV
D
P
V
A
V
L
A
V
F
E
NIH--VN
E
Q
L
Y
I
L
V
F
G
E
S
L
L
N
D
A
V
----
T
V
V
L
Y
N
L
F
K
S
----------
F
CQMKT
I
E
T
I
D
V
F
A
G
I
A
N
F
F
V
V
G
I
G
-
G
V
L
I
G
I
F
L
G
F
I
A
A
F
T
T
RFTHN
I
R
V
I
E
----
P
L
F
V
F
L
Y
S
Y
L
S
Y
I
T
A
E
M
------
F
H
L
S
G
I
M
A
I
T
A
C
A
M
T
M
N
K
Y
V
----
E
E
NVS-----QKS
Y
T
T
I
K
Y
---
F
M
K
M
L
S
S
V
S
E
T
L
I
-
F
I
F
M
G
V
S
TVGKNHEW-N
W
A
F
--
V
C
F
T
L
A
F
C
L
M
W
R
A
L
G
V
F
V
L
T
Q
V
I
N
R
FR----TI
P
L
----
T
FKD
Q
F
I
I
A
YG-G
L
R
G
A
I
C
F
A
L
V
F
L
L
P
A
A
VFPRK------------K
L
F
I
T
A
A
I
V
V
I
F
F
T
V
F
I
L
G
I
T
I
R
P
L
V
E
F
L
D
VKRSN
K
K
Q
Q
A
V
S
E
E
I
Y
C
R
L
F
D
H
V
K
T
G
I
E
D
V
C
G
HWG
H
N
F
W
R
D
K
F
K
KF
D
D
K
Y
L
R
K
L
L
IRENQP
K
S
S
I
V
S
L
Y
K
K
L
E
I
K
H
A
I
E
M
A
ETGMISTV
P
T
F
A
S
L
N
D
C
R
E
E
K
I
R
K
VTSS
E
T
D
E
I
R
E
L
L
S
R
N
L
Y
Q
I
R
Q
R
T
LSYNRHSLTAD
T
S
E
R
Q
A
K
E
I
L
I
R
R
R
H
S
L
R
E
S
I
R
KDSSL
N
R
E
HRASTSTS
R
Y
LSLPKNTK
L
P
E
K
L
Q
KR
R
T
I
S
IADGNSSDSDADAG
T
T
V
L
NL
Q
P
R
A
R
R
F
L
P
E
Q
F
SKKS
P
Q
SYKMEWKNEVDVDSGRDMPSTPPTP---HSREKGTQTS
G
L
L
QQPLLSKDQSGSERED
S
L
TEGIPPKPPP
R
L
V
W
RASEPGSRKARFGSEKP
32
Fugue
90.88
18%
-158
- C2 -
4CZB
-
NAH1_METJA
A:
[1-415]
------------------------------------------------------------------------------------
M
E
L
M
M
A
I
G
Y
L
G
L
A
L
V
L
G
S
L
V
A
K
I
A
E
K
L
K
I
P
D
I
P
L
L
L
L
L
G
L
I
I
G
P
F
L
Q
I
I
P
S
D
S
A
M
E
I
F
E
Y
A
G
P
I
G
L
I
F
I
L
L
G
G
A
F
T
M
R
I
S
L
L
K
R
V
I
---
K
T
V
---
V
R
L
D
T
-----------
I
T
F
L
I
T
L
L
I
S
G
F
I
F
N
M
V
L
N
L
P
Y
TS
P
V
G
Y
L
F
G
A
I
T
A
A
T
D
P
A
T
L
I
P
V
F
S
R
V
R
--
T
N
P
E
V
A
I
T
L
E
A
E
S
I
F
N
D
P
L
----
G
I
V
S
T
S
V
I
L
G
----------
L
F
G
L
F
S
S
S
N
P
L
I
D
L
I
T
L
A
G
G
A
I
V
V
G
-
L
L
L
A
K
I
Y
E
K
I
I
I
H
C
D
F
H
E
Y
V
A
P
L
V
L
G
----
G
A
M
L
L
L
Y
V
G
D
D
L
L
P
S
I
C
G-----
Y
G
F
S
G
Y
M
A
V
A
I
M
G
L
Y
L
G
D
A
L
----
F
R
A
-
D
-----
D
I
D
Y
K
Y
I
V
S
---
F
C
D
D
L
S
L
L
A
R
V
F
I
-
F
V
F
L
G
A
C
-
I
K
L
S
M
L
E
-
N
Y
F
I
--
P
G
L
L
V
A
L
G
S
I
F
L
A
R
P
L
G
V
F
L
G
L
I
G
S
--------
K
H
----
S
F
K
E
K
L
Y
F
A
L
E
-
G
P
R
G
V
V
P
A
A
L
A
V
T
V
G
I
E
I
L
K
N
A
DKIPA
S
I
T
K
Y
IT
P
T
D
I
A
G
T
I
I
I
G
T
F
M
T
I
L
L
S
V
I
L
E
A
S
W
A
G
M
L
A
L
K
L
L
G
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
79.38
23%
-115
- C2 -
4CZA
2
?
A:
[115-365]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
F
L
L
G
-----
F
L
F
G
A
I
I
G
A
T
D
P
A
T
L
I
P
L
F
R
Q
Y
R
--
V
K
Q
D
I
E
T
V
I
V
T
E
S
I
F
N
D
P
L
----
G
I
V
L
T
L
I
A
I
S
M
L
VPGYGGG
I
F
S
T
L
S
--
E
K
L
G
I
Y
A
G
G
V
I
Y
F
L
Y
N
V
S
V
S
I
S
L
G
I
F
L
G
I
L
G
---
Y
K
F
I
K
R
T
G
I
F
D
FP
E
I
E
A
F
S
L
S
L
A
F
L
G
F
F
I
G
E
R
------
L
D
A
S
G
Y
L
V
A
T
V
T
G
I
V
L
G
N
Y
K
LLKP
R
E
N
I
R
I
L
K
R
L
Q
R
A
I
E
K
E
V
H
---
F
N
D
T
L
A
A
L
A
T
I
F
I
-
F
V
L
L
G
A
E
M
---
N
L
E
V
-
I
W
S
------
N
L
G
K
G
L
L
-
V
A
L
G
V
M
I
L
A
R
---
P
L
A
----
T
L
P
L
LKWW
N
F
R
E
Y
L
F
I
A
L
E
-
G
P
R
G
V
V
P
S
A
L
A
S
L
P
L
S
L
A
L
K
Y
K
------------
S
P
L
L
T
V
H
W
G
E
I
I
M
A
T
V
V
I
T
V
L
T
S
V
I
V
E
T
L
W
I
P
I
L
K
D
K
L
D
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
78.30
23%
-117
- C2 -
4CZ9
-
?
A:
[115-365]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
F
L
L
G
-----
F
L
F
G
A
I
I
G
A
T
D
P
A
T
L
I
P
L
F
R
Q
Y
R
--
V
K
Q
D
I
E
T
V
I
V
T
E
S
I
F
N
D
P
L
----
G
I
V
L
T
L
I
A
I
S
M
L
VPGYGGG
I
F
S
T
L
S
--
E
K
L
G
I
Y
A
G
G
V
I
Y
F
L
Y
N
V
S
V
S
I
S
L
G
I
F
L
G
I
L
G
---
Y
K
F
I
K
R
T
G
I
F
D
F
P
E
I
E
A
F
S
L
S
L
A
F
L
G
F
F
I
G
E
R
------
L
D
A
S
G
Y
L
V
A
T
V
T
G
I
V
L
G
N
Y
K
LLKP
R
E
N
I
R
I
L
K
R
L
Q
R
A
I
E
K
E
V
H
---
F
N
D
T
L
A
A
L
A
T
I
F
I
-
F
V
L
L
G
A
E
M
---
N
L
E
V
-
I
W
S
------
N
L
G
K
G
L
L
-
V
A
L
G
V
M
I
L
A
R
---
P
L
A
----
T
L
P
L
LKWW
N
F
R
E
Y
L
F
I
A
L
E
-
G
P
R
G
V
V
P
S
A
L
A
S
L
P
L
S
L
A
L
K
Y
K
------------
S
P
L
L
T
V
H
W
G
E
I
I
M
A
T
V
V
I
T
V
L
T
S
V
I
V
E
T
L
W
I
P
I
L
K
D
K
L
D
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
77.90
23%
-115
- C2 -
4CZ8
3
?
A:
[115-365]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
F
L
L
G
-----
F
L
F
G
A
I
I
G
A
T
D
P
A
T
L
I
P
L
F
R
Q
Y
R
--
V
K
Q
D
I
E
T
V
I
V
T
E
S
I
F
N
D
P
L
----
G
I
V
L
T
L
I
A
I
S
M
L
V
PGYGGG
I
F
S
T
L
S
--
E
K
L
G
I
Y
A
G
G
V
I
Y
F
L
Y
N
V
S
V
S
I
S
L
G
I
F
L
G
I
L
G
---
Y
K
F
I
K
R
T
G
I
F
D
FP
E
I
E
A
F
S
L
S
L
A
F
L
G
F
F
I
G
E
R
------
L
D
A
S
G
Y
L
V
A
T
V
T
G
I
V
L
G
N
Y
K
LLKP
R
E
N
I
R
I
L
K
R
L
Q
R
A
I
E
K
E
V
H
---
F
N
D
T
L
A
A
L
A
T
I
F
I
-
F
V
L
L
G
A
E
M
---
N
L
E
V
-
I
W
S
------
N
L
G
K
G
L
L
-
V
A
L
G
V
M
I
L
A
R
---
P
L
A
----
T
L
P
L
LKWW
N
F
R
E
Y
L
F
I
A
L
E
-
G
P
R
G
V
V
P
S
A
L
A
S
L
P
L
S
L
A
L
K
Y
K
------------
S
P
L
L
T
V
H
W
G
E
I
I
M
A
T
V
V
I
T
V
L
T
S
V
I
V
E
T
L
W
I
P
I
L
K
D
K
L
D
V
G
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
68.15
23%
-110
- C2 -
4CZB
-
NAH1_METJA
A:
[123-354]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
F
G
A
I
T
A
A
T
D
P
A
T
L
I
P
V
F
S
R
V
R
--
T
N
P
E
V
A
I
T
L
E
A
E
S
I
F
N
D
P
L
G
I
V
S
T
S
V
I
L
G
L
F
G
L
----------
F
S
S
S
N
P
L
I
D
L
I
T
L
A
G
---------
G
-
A
I
V
V
G
L
L
L
A
K
I
Y
E
K
I
I
I
H
C
D
F
H
E
Y
V
A
----
P
L
V
L
G
G
A
M
L
L
L
Y
V
G
D
D
L
L
P
S
I
CG
Y
G
F
S
G
Y
M
A
V
A
----
I
M
G
L
Y
L
----
G
D
A
L
F
-----
R
A
D
D
I
D
Y
K
Y
I
V
S
F
C
D
D
L
S
L
L
A
R
V
F
I
-
F
V
F
L
G
-
A
C
I
K
L
S
M
L
E
-
N
Y
F
I
P
G
L
L
V
A
L
G
S
I
F
L
A
R
P
L
G
V
F
L
--
G
L
I
G
S
K
H
------------
S
F
K
E
K
L
Y
F
A
L
E
-
G
P
R
G
V
V
P
A
A
L
A
V
T
V
G
I
E
I
L
K
N
A
------------
D
K
I
P
A
S
I
T
K
Y
I
T
P
T
D
I
A
G
T
I
I
I
G
T
F
M
T
I
L
L
S
V
I
L
E
A
S
W
A
G
M
L
A
L
K
L
L
G
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
63.27
23%
-95
- C2 -
4D0A
-
NAH1_METJA
B:
[123-354]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
F
G
A
I
T
A
A
T
D
P
A
T
L
I
P
V
F
S
R
V
R
--
T
N
P
E
V
A
I
T
L
E
A
E
S
I
F
N
D
P
L
GIVS
T
S
V
I
L
G
L
F
G
L
----------
F
S
S
S
N
P
L
I
D
L
I
T
L
A
G
---------
G
-
A
I
V
V
G
L
L
L
A
K
I
Y
E
K
I
I
I
H
C
D
F
H
E
Y
V
A
----
P
L
V
L
G
G
A
M
L
L
L
Y
V
G
D
D
L
LPSICG
Y
G
F
S
G
Y
M
A
V
A
----
I
M
G
L
Y
L
----
G
D
A
L
F
-----
R
A
D
D
I
D
Y
K
Y
IVS
F
C
D
D
L
S
L
L
A
R
V
F
I
-
F
V
F
L
G
-
A
C
I
K
L
S
M
L
E
-
N
Y
F
I
PG
L
L
V
A
L
G
S
I
F
L
A
R
P
L
G
V
F
L
--
G
L
I
G
S
K
H
------------
S
F
K
E
K
L
Y
F
A
L
E
-
G
P
R
G
V
V
P
A
A
L
A
V
T
V
G
I
E
I
L
K
N
A
------------
D
K
I
P
A
S
I
T
K
Y
I
T
P
T
D
I
A
G
T
I
I
I
G
T
F
M
T
I
L
L
S
V
I
L
E
A
S
W
A
G
M
L
A
L
K
L
L
G
E
Y
K
P
K
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
HHSearch
53.99
13%
-115
- C2 -
1ZCD
-
NHAA_ECOLI
A:
[60-351]
-----------------------------------------------------------------------------------------------------------------------------------------
L
L
W
I
N
D
A
L
M
A
V
----
F
F
L
L
V
G
L
E
V
K
R
E
L
M
Q
G
S
L
ASL
R
Q
A
A
F
P
V
I
A
A
I
G
G
M
I
V
P
A
L
L
Y
L
A
F
N
Y
-----------
A
-
D
P
I
T
R
-----
E
G
W
A
I
-
P
A
A
T
D
I
A
F
A
L
G
V
L
A
L
L
G
SR
V
P
L
A
L
K
I
F
L
M
A
L
A
I
I
D
D
L
G
----
A
I
I
I
I
A
L
F
Y
T
----------
N
D
L
-------
S
M
----
A
S
L
----
G
--
V
A
A
V
A
I
A
V
L
A
V
L
N
---
L
-
C
G
A
R
R
--
T
----
G
V
Y
-
I
L
V
G
V
V
L
W
T
A
V
L
K
------
S
G
V
H
A
T
L
A
G
V
I
V
G
F
F
I
P
L
K
E
----
K
H
G
R
S
-----
P
-
A
K
R
L
E
H
V
---
L
H
P
W
V
A
Y
L
I
L
P
L
F
A
F
A
N
A
G
V
S
L
Q
G
V
T
L
D
G
L
T
S
I
L
--
P
L
G
I
I
A
G
L
L
I
G
K
P
L
G
I
S
L
F
C
W
L
A
L
R
L
K
LAHL
P
E
G
T
----
T
Y
Q
Q
I
M
V
V
G
I
L
C
G
I
G
F
T
M
S
I
F
I
A
S
L
A
F
G
S
V
D
P
E
L
------------
I
N
W
A
K
L
G
I
L
V
G
S
I
S
S
A
V
I
G
Y
S
W
L
R
V
R
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
31
Fugue
39.97
33%
190
- C2 -
2YGG
4
A:
[1-66]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
F
A
L
S
K
D
K
E
E
E
I
R
K
I
L
R
N
N
L
Q
K
T
R
Q
R
L
R
S
Y
N
R
H
T
L
V
A
D
P
Y
E
E
A
W
N
Q
M
L
L
R
R
Q
K
A
R
Q
L
E
Q
K
I
N
N
Y
L
T
----------------------------------------------------------------------------------------------------------------------------------------------------------------
21
HHSearch
38.58
35%
195
- C2 -
2YGG
4
A:
[3-66]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
L
S
K
D
K
E
E
E
I
R
K
I
L
R
N
N
L
Q
K
T
R
Q
R
L
R
S
Y
N
R
H
T
L
V
A
D
P
Y
E
E
A
W
N
Q
M
L
L
R
R
Q
K
A
R
Q
L
E
Q
K
--------------
I
N
N
Y
L
T
--------------------------------------------------------------------------------------------------------------------------------------------------
40
Fugue
38.44
13%
84
- C1 -
4GKW
-
SAS6_CAEEL
A:
[250-407]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
D
K
E
D
E
V
A
D
L
K
Q
D
T
E
S
L
Q
K
Q
L
E
E
N
Q
E
E
L
E
I
V
G
N
M
L
R
E
E
Q
G
K
V
D
Q
L
Q
K
R
N
V
A
H
Q
K
E
I
G
K
L
--
R
A
E
L
G
T
A
Q
R
N
L
E
K
A
D
Q
L
L
K
R
N
S
Q
Q
Q
N
Q
Q
S
L
D
M
R
K
L
G
E
L
E
A
D
L
K
E
K
D
S
M
V
E
S
L
T
E
T
I
G
I
L
R
K
E
L
E
N
E
K
L
K
A
A
E
N
M
D
S
F
E
K
L
S
M
E
N
E
N
L
K
E
K
I
A
H
Y
R
A
Q
R
F
--------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
36.74
41%
248
- C2 -
2YGG
4
A:
[4-54]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
S
K
D
K
E
E
E
I
R
K
I
L
R
N
N
L
Q
K
T
R
Q
R
L
R
S
Y
N
R
H
T
L
V
A
D
P
Y
E
E
A
W
N
Q
M
L
L
R
R
Q
K
A
R
Q
L
E
Q
K
I
N
N
Y
L
T
----------------------------------------------------------------------------------------------------------------------------------------------------------------
17
PsiBlast_PDB
36.57
27%
238
- C2 -
3KGF
8
AROG_MYCTU
A:
[4-78]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
W
T
V
D
I
P
I
D
--------
P
P
L
P
T
D
L
R
T
R
L
D
A
A
L
A
K
P
A
A
Q
Q
P
T
W
P
A
D
Q
A
L
A
M
R
--
T
V
L
E
S
V
P
P
V
T
V
P
S
E
I
V
R
L
Q
E
Q
L
A
Q
V
A
K
G
E
A
F
L
L
15
PsiBlast_PDB
36.48
27%
210
- C2 -
2W19
3
AROG_MYCTU
A:
[13-86]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
W
T
V
D
I
P
I
D
Q
---
L
P
S
L
P
P
L
P
T
D
L
R
T
R
L
D
A
A
L
A
K
P
A
A
Q
Q
P
T
W
P
A
D
Q
A
L
A
M
R
--
T
V
L
E
S
V
P
P
V
T
V
P
S
E
I
V
R
L
Q
E
Q
L
A
Q
V
A
K
G
E
A
F
L
L
19
PsiBlast_PDB
36.04
27%
213
- C2 -
3NUE
3
AROG_MYCTU
A:
[3-78]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
N
W
T
V
D
I
P
I
D
Q
---
L
P
S
L
P
P
L
P
T
D
L
R
T
R
L
D
A
A
L
A
K
P
A
A
Q
Q
P
T
W
P
A
D
Q
A
L
A
M
R
--
T
V
L
E
S
V
P
P
V
T
V
P
S
E
I
V
R
L
Q
E
Q
L
A
Q
V
A
K
G
E
A
F
L
L
16
PsiBlast_PDB
35.83
27%
227
- C2 -
2W1A
-
AROG_MYCTU
A:
[13-86]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
W
T
V
D
I
P
I
D
Q
---
L
P
S
L
P
P
L
P
T
D
L
R
T
R
L
D
A
A
L
A
K
P
A
A
Q
Q
P
T
W
P
A
D
Q
A
L
A
M
R
--
T
V
L
E
S
V
P
P
V
T
V
P
S
E
I
V
R
L
Q
E
Q
L
A
Q
V
A
K
G
E
A
F
L
L
20
PsiBlast_PDB
35.42
27%
220
- C2 -
3NV8
-
AROG_MYCTU
A:
[3-78]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
N
W
T
V
D
I
P
I
D
Q
---
L
P
S
L
P
P
L
P
T
D
L
R
T
R
L
D
A
A
L
A
K
P
A
A
Q
Q
P
T
W
P
A
D
Q
A
L
A
M
R
--
T
V
L
E
S
V
P
P
V
T
V
P
S
E
I
V
R
L
Q
E
Q
L
A
Q
V
A
K
G
E
A
F
L
L
18
PsiBlast_PDB
34.37
27%
230
- C2 -
3NUD
1
AROG_MYCTU
A:
[5-78]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
W
T
V
D
I
P
I
------
P
S
L
P
P
L
P
T
D
L
R
T
R
L
D
A
A
L
A
K
P
A
A
Q
Q
P
T
W
P
A
D
Q
A
L
A
M
R
--
T
V
L
E
S
V
P
P
V
T
V
P
S
E
I
V
R
L
Q
E
Q
L
A
Q
V
A
K
G
E
A
F
L
L
2
PsiBlast_PDB
27.31
45%
323
- C2 -
2E30
-
B:
[1-42]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
D
L
L
A
V
K
K
K
Q
E
T
K
R
S
I
N
E
E
I
H
T
Q
F
L
D
H
L
L
T
G
I
E
D
I
C
G
H
Y
G
H
H
H
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
37
Fugue
27.09
44%
318
* C2 *
2E30
-
B:
[1-43]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
D
L
L
A
V
K
K
K
Q
E
T
K
R
S
I
N
E
E
I
H
T
Q
F
L
D
H
L
L
T
G
I
E
D
I
C
G
H
Y
G
H
H
H
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
PsiBlast_PDB
21.84
32%
119
- C- -
3J32
-
?
A:
[2912-2966]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
L
I
R
K
E
V
D
L
L
S
L
K
E
A
N
----
A
I
K
D
A
L
Y
K
L
Q
N
D
H
S
K
G
G
F
E
E
I
A
G
Y
--
H
G
Y
P
N
K
C
P
E
K
G
D
D
K
Y
P
C
C
V
H
G
M
P
I
F
P
H
W
R
R
L
H
T
I
Q
M
E
R
A
L
K
N
H
G
S
Q
I
G
I
P
Y
W
N
W
T
K
R
M
S
S
I
P
A
F
F
G
D
D
S
N
N
N
P
F
Y
K
Y
H
I
R
A
V
N
Q
Y
T
T
R
D
V
D
V
E
L
F
N
Q
T
K
F
G
E
Y
D
Y
L
Y
Y
S
T
L
Q
V
L
E
E
N
S
F
C
G
F
E
V
Q
Y
E
I
L
H
S
A
V
H
A
W
L
G
G
A
G
K
Y
S
M
S
T
L
E
Y
S
A
Y
D
P
V
F
M
I
H
H
S
S
L
D
R
I
W
I
L
W
Q
Q
L
Q
K
R
R
M
K
L
Y
Y
A
A
D
C
A
G
D
L
M
K
F
P
M
H
P
F
S
Y
K
S
E
N
E
D
E
F
T
R
V
N
S
V
P
N
I
V
F
D
H
Y
K
F
N
Y
D
---
Y
D
N
M
R
I
R
G
H
D
I
N
E
L
E
A
I
I
N
E
L
R
N
K
D
R
I
F
A
G
F
V
L
S
G
I
R
I
T
A
T
V
K
V
F
I
H
G
T
G
A
T
D
H
E
E
F
A
G
K
F
A