@TOME V2.2
(Nov 2016)
Ref.
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : SL9A4_HUMAN: (2015-12-12 )
MALQMFVTYSPWNCLLLLVALECSEASSDLNESANSTAQYASNAWFAAASSEPEEGISVFELDYDYVQIPYEVTLWILLASLAKIGFHLYHRLPGLMPESCLLILVGALVGGIIFGTDHKSPPVMDSSIYFLYLLPPIVLEGGYFMPTRPFFENIGSILWWAVLGALINALGIGLSLYLICQVKAFGLGDVNLLQNLLFGSLISAVDPVAVLAVFEEARVNEQLYMMIFGEALLNDGITVVLYNMLIAFTKMHKFEDIETVDILAGCARFIVVGLGGVLFGIVFGFISAFITRFTQNISAIEPLIVFMFSYLSYLAAETLYLSGILAITACAVTMKKYVEENVSQTSYTTIKYFMKMLSSVSETLIFIFMGVSTVGKNHEWNWAFICFTLAFCQIWRAISVFALFYISNQFRTFPFSIKDQCIIFYSGVRGAGSFSLAFLLPLSLFPRKKMFVTATLVVIYFTVFIQGITVGPLVRYLDVKKTNKKESINEELHIRLMDHLKAGIEDVCGHWSHYQVRDKFKKFDHRYLRKILIRKNLPKSSIVSLYKKLEMKQAIEMVETGILSSTAFSIPHQAQRIQGIKRLSPEDVESIRDILTSNMYQVRQRTLSYNKYNLKPQTSEKQAKEILIRRQNTLRESMRKGHSLPWGKPAGTKNIRYLSYPYGNPQSAGRDTRAAGFSDDDSSDPGSPSITFSACSRIGSLQKQEAQEIIPMKSLHRGRKAFSFGYQRNTSQEEYLGGVRRVALRPKPLFHAVDEEGESGGESEGKASLVEVRSRWTADHGHGRDHHRSHSPLLQKK
Atome Classification :
(20 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.....----..140.......150...---...---.160.......170.......180.......190.......200.......210.......--220.......230.......240----......----.250..------....-.260.......270....-...280......-.290.......300.......310.........320------.......330.......----340..-----.....350......-.360....-...370.......380........390....--...400.......410----.......420.....-..430.......440.......------------450.......460.......470.......480.....-..490.......500.......510.......520.......530.......540.......550.......560.--......570.......580.......590.......600.......610.......620.......630.......640.......650.......660.......670.......680.......690.......700.......710.......720.......730.......740.......750.......760.......770.......780.......790......
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
M
A
L
Q
M
F
V
TYSP
W
N
C
L
L
L
L
V
A
LECSEASS
D
L
N
E
SAN
S
T
A
Q
YASN
A
W
F
AAASSEPEEG
I
S
V
F
E
L
DY
D
Y
V
QI
P
Y
E
V
T
L
W
I
L
L
A
S
L
A
K
I
G
F
H
L
Y
H
RLPGLM
P
E
S
C
L
L
I
L
V
G
A
L
V
G
G
I
I
FGTDHKSPPVMDS
S
I
Y
F
L
Y
LL
P
P
----
I
VLEGGYFMPT
R
P
F
F
E
N
I
---
G
S
I
---
L
W
W
A
V
L
G
A
L
I
N
A
L
G
I
G
L
S
L
Y
L
I
C
Q
V
K
AFGLG
D
V
N
L
L
Q
N
L
L
F
G
S
L
I
S
AV
D
P
V
A
V
L
A
V
F
E
E
AR--VN
E
Q
L
Y
M
M
I
F
G
E
A
L
LND
G
I
T
V
V
L
----
Y
N
M
L
I
A
----
F
T
K
MHK------FED
I
-
E
T
V
D
I
L
A
G
C
A
R
F
I
V
V
G
L
G
-
G
V
L
F
G
I
V
F
G
F
I
S
-
A
F
I
T
R
F
T
Q
N
I
S
A
I
E
P
L
I
V
F
M
F
S
--
Y
L
S
Y
L
A
A
E
T
L
Y
L
------
S
G
I
L
A
I
T
A
C
A
V
T
M
K
K
Y
V
----
E
E
N
VS-----QT
S
Y
T
T
I
K
Y
F
M
K
M
L
-
S
S
V
S
E
T
L
I
-
F
I
F
M
G
V
S
TVGKNHEW-
N
W
A
F
I
C
F
T
L
A
F
C
Q
I
W
--
R
A
I
S
V
F
A
L
F
Y
ISNQFR----TFPFSIKD
Q
C
I
I
F
Y
S-GVRGAGS
F
S
L
A
F
L
L
PLSLFPRK------------
K
M
F
V
T
A
T
L
V
V
I
Y
F
T
V
F
IQGI
T
V
G
P
L
V
R
Y
LDVKKTNKKE-SI
N
E
E
L
H
I
R
L
M
D
H
L
K
A
G
I
E
D
V
CGHWS
H
Y
Q
V
R
D
K
F
K
K
F
D
H
R
Y
L
R
K
I
L
I
RKNL
P
K
S
S
I
V
S
L
Y
K
K
L
E
M
K
Q
A
I
E
M
V
E
T
GI--LS
S
T
AFSI
P
H
Q
A
Q
R
I
Q
G
I
KRL
S
P
E
D
V
E
S
I
R
D
I
L
T
S
N
M
Y
Q
V
R
Q
R
TLSYNKYNLKPQT
S
E
K
Q
A
K
E
I
L
I
R
R
Q
N
T
L
R
E
S
M
R
KGHSLPWGKPAGTKN
I
R
Y
L
SYPYGNPQSAGRDTRAAGFSDDDSSDPGSP
S
I
T
F
S
A
C
S
R
I
G
S
L
Q
K
Q
E
A
Q
EII
P
M
K
S
L
HRGRK
A
F
S
FGYQRNT
S
Q
E
E
Y
L
G
G
V
R
RVALRPK
P
L
F
H
AVDEEGESGGESEG
K
A
S
L
V
E
V
R
S
R
WTADHGHGRDHHRSHSPLLQKK
37
Fugue
97.02
18%
-136
- C3 -
4CZB
-
NAH1_METJA
A:
[1-415]
-------------------------------------------------------------------------
M
E
L
M
M
A
I
G
Y
L
G
L
A
L
V
L
G
S
L
V
A
K
I
A
E
K
L
K
I
P
D
I
P
L
L
L
L
L
G
L
I
I
G
P
F
L
Q
I
I
P
S
D
S
A
M
E
I
F
E
Y
A
G
P
I
G
L
I
F
I
L
L
G
G
A
F
T
M
R
I
S
L
L
K
R
V
I
---
K
T
V
---
V
R
L
D
T
I
T
F
L
I
T
L
L
I
S
G
F
I
F
N
M
V
L
N
L
P
Y
------
T
S
P
V
G
Y
L
F
G
A
I
T
A
A
T
D
P
A
T
L
I
P
V
F
S
R
V
R
--
T
N
P
E
V
A
I
T
L
E
A
E
S
I
F
N
D
P
L
G
I
V
S
----
T
S
V
I
L
G
----
L
F
G
L
F
S
------
S
S
N
---------
P
L
I
D
L
I
T
L
A
G
G
-
A
I
V
V
G
L
L
L
A
K
I
Y
-
E
K
I
I
I
H
C
D
F
H
E
Y
V
A
P
L
V
L
G
G
A
M
--
L
L
L
Y
V
G
D
D
L
L
P
S
I
CG
Y
G
F
S
G
Y
M
A
V
A
I
M
G
L
Y
L
G
D
A
L
----
F
R
A
-
D
-----
D
I
D
Y
K
Y
I
V
S
F
C
D
D
L
-
S
L
L
A
R
V
F
I
-
F
V
F
L
G
A
C
-
I
K
L
S
M
L
E
-
N
Y
F
I
P
G
L
L
V
A
L
G
S
I
F
L
A
R
P
L
G
V
F
L
G
L
I
G
S
K
----------
H
S
F
K
E
K
L
Y
F
A
L
E
-
G
P
R
G
V
V
P
A
A
L
A
V
T
V
G
I
E
I
L
K
N
A
DKIPA
S
I
T
K
Y
IT
P
T
D
I
A
G
T
I
I
I
G
T
F
M
T
I
L
L
S
V
I
L
E
A
S
W
A
G
M
L
A
L
K
L
L
G
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
63.92
24%
-135
- C2 -
4CZA
2
?
A:
[115-320]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
F
L
L
G
F
L
F
G
A
I
I
G
A
T
D
P
A
T
L
I
P
L
F
R
Q
Y
R
--
V
K
Q
D
I
E
T
V
I
V
T
E
S
I
F
N
D
P
L
G
I
V
L
------
T
L
I
A
----
I
S
M
L
V
P
GYGGG
I
F
S
T
L
S
E
K
L
G
I
Y
A
G
G
V
I
Y
F
L
Y
N
V
S
V
S
I
S
L
G
I
F
L
G
I
L
G
Y
K
F
I
K
R
--
T
G
I
F
D
F
P
E
I
E
A
F
S
L
S
L
A
F
L
G
F
F
I
G
E
R
L
D
A
------
S
G
Y
L
V
A
T
V
T
G
I
V
L
G
N
Y
K
LLKP
R
E
N
I
R
I
L
K
R
L
Q
R
A
I
E
K
E
V
H
F
N
D
T
L
-
A
A
L
A
T
I
F
I
-
F
V
L
L
G
A
E
M
---
N
L
E
V
-
I
W
S
N
L
G
K
G
L
L
V
A
L
G
V
--
M
I
L
A
R
P
L
A
T
L
P
L
L
K
W
W
----
N
F
R
E
Y
L
F
I
A
L
E
G
P
R
G
-
V
V
P
S
A
L
A
S
L
P
L
S
L
A
L
K
Y
K
S
P
L
L
------------
T
V
H
W
G
E
I
I
M
A
T
V
V
I
T
V
L
T
S
V
I
V
E
T
L
W
I
P
I
L
K
D
K
L
D
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
63.02
24%
-135
- C2 -
4CZ8
3
?
A:
[115-320]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
F
L
L
G
F
L
F
G
A
I
I
G
A
T
D
P
A
T
L
I
P
L
F
R
Q
Y
R
--
V
K
Q
D
I
E
T
V
I
V
T
E
S
I
F
N
D
P
L
G
I
V
L
------
T
L
I
A
----
I
S
M
L
V
P
GYGGG
I
F
S
T
L
S
E
K
L
G
I
Y
A
G
G
V
I
Y
F
L
Y
N
V
S
V
S
I
S
L
G
I
F
L
G
I
L
G
Y
K
F
I
K
R
--
T
G
I
F
D
F
P
E
I
E
A
F
S
L
S
L
A
F
L
G
F
F
I
G
E
R
L
D
A
------
S
G
Y
L
V
A
T
V
T
G
I
V
L
G
N
Y
K
LLKP
R
E
N
I
R
I
L
K
R
L
Q
R
A
I
E
K
E
V
H
F
N
D
T
L
-
A
A
L
A
T
I
F
I
-
F
V
L
L
G
A
E
M
---
N
L
E
V
-
I
W
S
N
L
G
K
G
L
L
V
A
L
G
V
--
M
I
L
A
R
P
L
A
T
L
P
L
L
K
W
W
----
N
F
R
E
Y
L
F
I
A
L
E
G
P
R
G
-
V
V
P
S
A
L
A
S
L
P
L
S
L
A
L
K
Y
K
S
P
L
L
------------
T
V
H
W
G
E
I
I
M
A
T
V
V
I
T
V
L
T
S
V
I
V
E
T
L
W
I
P
I
L
K
D
K
L
D
V
G
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
60.68
24%
-112
- C2 -
4CZ9
-
?
A:
[115-320]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
F
L
L
G
F
L
F
G
A
I
I
G
A
T
D
P
A
T
L
I
P
L
F
R
Q
Y
R
--
V
K
Q
D
I
E
T
V
I
V
T
E
S
I
F
N
D
P
L
G
I
V
L
T
L
I
A
I
S
M
L
V
P
----
G
Y
G
G
G
I
------
F
S
T
L
S
E
K
L
G
I
Y
A
G
G
V
I
Y
F
L
Y
N
V
S
V
S
I
S
L
G
I
F
L
G
I
L
G
Y
K
F
I
K
R
--
T
G
I
F
D
F
P
E
I
E
A
F
S
L
S
L
A
F
L
G
F
F
I
G
E
R
L
D
A
------
S
G
Y
L
V
A
T
V
T
G
I
V
L
G
N
Y
K
LLKP
R
E
N
I
R
I
L
K
R
L
Q
R
A
I
E
K
E
V
H
F
N
D
T
L
-
A
A
L
A
T
I
F
I
-
F
V
L
L
G
A
E
M
---
N
L
E
V
-
I
W
S
N
L
G
K
G
L
L
V
A
L
G
V
--
M
I
L
A
R
P
L
A
T
L
P
L
L
K
W
W
----
N
F
R
E
Y
L
F
I
A
L
E
G
P
R
G
-
V
V
P
S
A
L
A
S
L
P
L
S
L
A
L
K
Y
K
S
P
L
L
------------
T
V
H
W
G
E
I
I
M
A
T
V
V
I
T
V
L
T
S
V
I
V
E
T
L
W
I
P
I
L
K
D
K
L
D
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
HHSearch
52.45
12%
-116
* C3 *
1ZCD
-
NHAA_ECOLI
A:
[60-352]
------------------------------------------------------------------------------------------------------------------------------
L
L
W
I
N
D
A
L
M
A
V
----
F
F
L
L
V
G
L
E
V
K
R
E
L
M
Q
G
S
L
ASL
R
Q
A
A
F
P
V
I
A
A
I
G
G
M
I
V
P
A
L
L
Y
L
A
F
N
Y
-----------
A
-
D
P
I
T
R
E
G
W
A
I
-
P
A
A
T
D
I
A
F
A
L
G
V
L
A
L
L
G
SR
V
P
L
A
L
K
I
F
L
M
A
L
A
I
I
D
D
L
G
A
I
I
I
----
I
A
L
F
Y
T
----
N
D
L
--------------
S
---
M
A
-----
S
L
---
G
--
V
A
A
V
A
I
A
V
L
A
V
L
-
N
L
----
C
G
A
R
R
-
T
-
G
V
Y
-
I
L
V
G
--
V
V
L
W
T
A
V
L
K
S
G
V
------
H
A
T
L
A
G
V
I
V
G
F
F
I
P
L
K
E
----
K
H
G
R
S
-----
P
--
A
K
R
L
E
H
V
L
H
P
W
V
A
Y
L
I
L
P
L
F
A
F
A
N
A
G
V
S
L
Q
G
V
T
L
D
G
L
T
S
I
L
P
L
G
I
I
A
G
L
L
I
G
--
K
P
L
G
I
S
L
F
C
W
L
A
L
R
L
K
LAHL
P
E
G
T
T
Y
Q
Q
I
M
V
V
G
I
L
C
G
I
G
F
T
M
S
I
F
I
A
S
L
A
F
G
S
V
D
P
E
L
------------
I
N
W
A
K
L
G
I
L
V
G
S
I
S
S
A
V
I
G
Y
S
W
L
R
V
R
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
31
Fugue
40.09
31%
202
- C2 -
2YGG
4
A:
[1-66]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
F
A
L
S
K
D
K
E
E
E
I
R
K
I
L
R
N
N
L
Q
K
T
R
Q
R
L
R
S
Y
N
R
H
T
L
V
A
D
P
Y
E
E
A
W
N
Q
M
L
L
R
R
Q
K
A
R
Q
L
E
Q
K
I
N
N
Y
L
T
--------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
39.51
31%
-27
- C2 -
4CZB
-
NAH1_METJA
A:
[123-199]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
F
G
A
I
T
A
A
T
D
P
A
T
L
I
P
V
F
S
R
V
R
--
T
N
P
E
V
A
I
T
L
E
A
E
S
I
F
N
D
P
L
G
I
V
S
----
T
S
V
I
L
G
L
F
GL
F
S
S
S
N
P
------
L
I
D
L
-
I
T
---
L
A
G
G
A
--
I
V
V
G
L
L
-
L
A
K
I
Y
E
K
I
I
I
H
C
-
D
F
H
E
Y
V
A
P
L
V
L
G
G
A
M
L
L
L
Y
V
G
D
--
D
L
L
P
S
I
C
G
Y
G
F
S
------
G
Y
M
A
V
A
I
M
G
L
Y
L
G
D
A
L
F
----
R
A
D
D
I
-----
D
Y
K
Y
I
V
S
F
C
D
D
L
S
L
-
L
A
R
V
F
I
F
V
-
F
L
G
A
C
I
K
L
S
M
L
E
N
Y
F
-
I
P
G
L
L
V
A
L
G
S
I
F
L
A
R
--
P
L
G
V
F
L
G
L
I
G
S
K
H
S
F
K
----
E
K
L
Y
F
A
L
E
G
P
R
G
V
V
P
-
A
A
L
A
V
T
V
G
I
E
I
L
K
N
A
D
K
I
P
A
S
I
------------
T
K
Y
I
T
P
T
D
I
A
G
T
I
I
I
G
T
F
M
T
I
L
L
S
V
I
L
E
A
S
W
A
G
M
L
A
L
K
-
L
L
G
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
PsiBlast_CBE
38.91
31%
-17
- C2 -
4CZB
1
NAH1_METJA
B:
[123-199]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
F
G
A
I
T
A
A
T
D
P
A
T
L
I
P
V
F
S
R
V
R
--
T
N
P
E
V
A
I
T
L
E
A
E
S
I
F
N
D
P
L
G
I
V
S
----
T
S
V
I
L
G
LFGL
F
S
S
S
N
P
------
L
I
D
L
-
I
T
---
L
A
G
G
A
--
I
V
V
G
L
L
-
L
A
K
I
Y
E
K
I
I
I
H
C
-
D
F
H
E
Y
V
A
P
L
V
L
G
G
A
M
L
L
L
Y
V
G
D
--
D
L
L
P
S
I
C
G
Y
G
F
S
------
G
Y
M
A
V
A
I
M
G
L
Y
L
G
D
A
L
F
----
R
A
D
D
I
-----
D
Y
K
Y
I
V
S
F
C
D
D
L
S
L
-
L
A
R
V
F
I
F
V
-
F
L
G
A
C
I
K
L
S
M
L
E
N
Y
F
-
I
P
G
L
L
V
A
L
G
S
I
F
L
A
R
--
P
L
G
V
F
L
G
L
I
G
S
K
H
S
F
K
----
E
K
L
Y
F
A
L
E
G
P
R
G
V
V
P
-
A
A
L
A
V
T
V
G
I
E
I
L
K
N
A
D
K
I
P
A
S
I
------------
T
K
Y
I
T
P
T
D
I
A
G
T
I
I
I
G
T
F
M
T
I
L
L
S
V
I
L
E
A
S
W
A
G
M
L
A
L
K
-
L
L
G
E
Y
K
P
K
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
HHSearch
38.07
33%
204
- C2 -
2YGG
4
A:
[2-66]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
A
L
S
K
D
K
E
E
E
I
R
K
I
L
R
N
N
L
Q
K
T
R
Q
R
L
R
S
Y
N
R
H
T
L
V
A
D
P
Y
E
E
A
W
N
Q
M
L
L
R
R
Q
K
A
R
Q
L
E
Q
K
--------------
I
N
N
Y
L
T
------------------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
36.27
31%
13
- C2 -
4D0A
-
NAH1_METJA
B:
[123-199]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
F
G
A
I
T
A
A
T
D
P
A
T
L
I
P
V
F
S
R
V
R
--
T
N
P
E
V
A
I
T
L
E
A
E
S
I
F
N
D
P
L
G
I
V
S
----
T
S
V
I
L
G
LFGL
F
S
S
S
N
P
------
L
I
D
L
-
I
T
---
L
A
G
G
A
--
I
V
V
G
L
L
-
L
A
K
I
Y
E
K
I
I
I
H
C
-
D
F
H
E
Y
V
A
P
L
V
L
G
G
A
M
L
L
L
Y
V
G
D
--
D
L
L
P
S
I
C
G
Y
G
F
S
------
G
Y
M
A
V
A
I
M
G
L
Y
L
G
D
A
L
F
----
R
A
D
D
I
-----
D
Y
K
Y
I
V
S
F
C
D
D
L
S
L
-
L
A
R
V
F
I
F
V
-
F
L
G
A
C
I
K
L
S
M
L
E
N
Y
F
-
I
P
G
L
L
V
A
L
G
S
I
F
L
A
R
--
P
L
G
V
F
L
G
L
I
G
S
K
H
S
F
K
----
E
K
L
Y
F
A
L
E
G
P
R
G
V
V
P
-
A
A
L
A
V
T
V
G
I
E
I
L
K
N
A
D
K
I
P
A
S
I
------------
T
K
Y
I
T
P
T
D
I
A
G
T
I
I
I
G
T
F
M
T
I
L
L
S
V
I
L
E
A
S
W
A
G
M
L
A
L
K
-
L
L
G
E
Y
K
P
K
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
35.20
40%
275
- C2 -
2YGG
4
A:
[4-52]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
S
K
D
K
E
E
E
I
R
K
I
L
R
N
N
L
Q
K
T
R
Q
R
L
R
S
Y
N
R
H
T
L
V
A
D
P
Y
E
E
A
W
N
Q
M
L
L
R
R
Q
K
A
R
Q
L
E
Q
K
I
N
N
Y
L
T
--------------------------------------------------------------------------------------------------------------------------------------------------------
20
PsiBlast_PDB
35.10
27%
136
- C2 -
3RQT
3
?
A:
[230-303]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
D
I
E
N
N
Q
N
L
K
V
S
K
E
S
G
F
R
T
S
L
L
M
Y
N
H
T
N
K
K
M
T
K
S
V
R
E
A
L
D
H
I
I
D
R
Q
G
-
I
A
D
H
I
Y
Q
G
Y
A
K
P
A
T
S
P
F
N
D
K
-
I
P
Y
I
K
E
P
K
L
T
K
Q
N
I
E
Q
A
K
M
L
L
A
K
D
G
Y
T
K
E
H
P
L
K
I
K
L
I
T
Y
D
G
R
P
E
L
S
K
I
A
Q
V
L
Q
S
D
A
K
K
A
N
I
E
I
D
I
K
S
V
D
D
I
E
G
Y
L
K
D
R
S
A
W
D
A
T
M
Y
S
F
G
T
I
P
R
G
D
T
G
Y
F
F
N
Q
A
Y
K
K
D
G
A
I
N
K
G
D
Y
N
N
S
N
V
D
D
L
I
N
Q
L
N
H
T
V
D
V
K
E
R
H
N
I
S
N
D
I
40
Fugue
34.90
8%
65
- C1 -
4BM5
-
?
A:
[33-348]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
N
L
I
D
F
Y
I
R
N
G
I
L
E
M
E
N
E
Q
A
V
Y
P
V
N
L
R
G
V
L
N
I
L
Q
E
M
Y
R
Q
Y
L
I
Q
S
F
A
A
K
S
R
T
E
K
E
R
L
F
N
N
L
A
H
L
G
N
I
L
G
V
N
A
I
H
S
N
I
G
S
V
I
Y
K
T
Y
A
S
Q
A
L
T
N
N
R
L
E
E
K
D
I
E
F
L
R
N
I
Q
N
M
L
S
M
D
E
A
T
C
R
T
L
L
Q
E
T
K
E
A
R
A
G
F
L
F
D
K
I
F
M
A
E
A
V
A
E
F
R
R
V
C
R
E
L
D
V
E
D
R
R
V
R
A
F
R
A
E
I
E
H
A
I
E
N
S
L
L
K
E
S
Q
E
E
L
G
I
S
A
E
K
A
R
Q
V
L
L
D
C
I
Q
D
R
C
E
A
L
I
V
Q
A
A
A
S
L
R
Q
R
R
Q
E
G
A
A
R
D
--
L
S
R
A
L
R
Q
E
L
Y
L
V
Y
Q
A
Y
A
L
G
T
A
R
S
N
A
E
N
D
Q
V
K
E
D
L
A
L
L
R
E
M
L
G
I
Q
A
A
----------------
14
PsiBlast_PDB
34.30
33%
114
- C2 -
2EJX
-
?
A:
[3-62]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
V
E
K
E
I
K
T
N
Q
D
I
D
V
V
M
T
-
I
--
F
S
D
P
A
F
T
I
P
Q
I
F
P
G
I
A
S
I
K
C
I
E
P
E
I
F
E
A
E
G
K
F
L
A
F
S
-
Y
K
V
K
G
R
V
Y
K
G
V
D
E
V
R
I
I
Y
D
S
D
R
G
N
G
I
L
Y
I
R
K
K
D
N
N
T
L
Q
I
I
L
E
H
D
N
K
L
T
A
F
L
G
K
P
Y
V
S
S
N
L
D
R
L
A
E
N
I
D
E
I
I
R
L
E
R
I
K
R
K
I
----------------------------------------------------------------------------------------------------------------------
15
PsiBlast_PDB
31.99
33%
110
- C2 -
3W9K
1
?
A:
[5-65]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
K
V
E
K
E
I
K
T
N
Q
D
I
D
V
V
M
T
-
I
--
F
S
D
P
A
F
T
I
P
Q
I
F
P
G
I
A
S
I
K
C
I
E
P
E
I
F
E
A
E
G
K
F
L
A
F
S
-
Y
K
V
K
G
R
V
Y
K
G
V
D
E
V
R
I
I
Y
D
S
D
R
G
N
G
I
L
Y
I
R
K
K
D
N
N
T
L
Q
I
I
L
E
H
D
N
K
L
T
A
F
L
G
K
P
Y
V
S
S
N
L
D
R
L
A
E
N
I
D
E
I
I
R
L
E
R
I
K
R
K
I
----------------------------------------------------------------------------------------------------------------------
17
PsiBlast_PDB
30.95
30%
116
* C5 *
2B59
-
?
A:
[96-165]
------------------------------------------------
A
D
N
D
P
E
K
G
I
L
N
F
A
L
A
Y
S
Y
I
A
G
Y
K
E
T
G
V
A
E
E
S
G
I
I
A
K
I
G
F
K
I
L
Q
K
K
S
T
A
V
K
F
Q
D
T
L
S
M
P
G
A
I
S
G
T
Q
L
F
D
W
D
G
E
V
I
T
G
Y
E
V
I
Q
P
D
V
L
S
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
33
Fugue
30.87
52%
328
- C2 -
2E30
-
B:
[1-43]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
D
L
L
A
V
K
K
K
Q
E
T
K
R
S
I
N
E
E
I
H
T
Q
F
L
D
H
L
L
T
G
I
E
D
I
C
G
H
Y
G
H
H
H
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
PsiBlast_PDB
30.42
30%
133
- C5 -
4FL4
-
?
B:
[96-165]
------------------------------------------------
A
D
N
D
P
E
K
G
I
L
N
F
A
L
A
Y
S
Y
I
A
G
Y
K
E
T
G
V
A
E
E
S
G
I
I
A
K
I
G
F
K
I
L
Q
K
K
S
T
A
V
K
F
Q
D
T
L
S
M
P
G
A
I
S
G
T
Q
L
F
D
W
D
G
E
V
I
T
G
Y
E
V
I
Q
P
D
V
L
S
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
PsiBlast_PDB
30.16
30%
126
- C5 -
2BM3
2
?
A:
[84-153]
------------------------------------------------
A
D
N
D
P
E
K
G
I
L
N
F
A
L
A
Y
S
Y
I
A
G
Y
K
E
T
G
V
A
E
E
S
G
I
I
A
K
I
G
F
K
I
L
Q
K
K
S
T
A
V
K
F
Q
D
T
L
S
M
P
G
A
I
S
G
T
Q
L
F
D
W
D
G
E
V
I
T
G
Y
E
V
I
Q
P
D
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
30.15
55%
376
- C2 -
2E30
-
B:
[8-43]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
K
Q
E
T
K
R
-
S
I
N
E
E
I
H
T
Q
F
L
D
H
L
L
T
G
I
E
D
I
C
G
H
Y
G
H
H
H
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------