@TOME V2.2
(Nov 2016)
Ref.
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : SL9A7_HUMAN: (2015-12-12 )
MEPGDAARPGSGRATGAPPPRLLLLPLLLGWGLRVAAAASASSSGAAAEDSSAMEELATEKEAEESHRQDSVSLLTFILLLTLTILTIWLFKHRRVRFLHETGLAMIYGLIVGVILRYGTPATSGRDKSLSCTQEDRAFSTLLVNVSGKFFEYTLKGEISPGKINSVEQNDMLRKVTFDPEVFFNILLPPIIFHAGYSLKKRHFFRNLGSILAYAFLGTAVSCFIIGNLMYGVVKLMKIMGQLSDKFYYTDCLFFGAIISATDPVTVLAIFNELHADVDLYALLFGESVLNDAVAIVLSSSIVAYQPAGLNTHAFDAAAFFKSVGIFLGIFSGSFTMGAVTGVNANVTKFTKLHCFPLLETALFFLMSWSTFLLAEACGFTGVVAVLFCGITQAHYTYNNLSVESRSRTKQLFEVLHFLAENFIFSYMGLALFTFQKHVFSPIFIIGAFVAIFLGRAAHIYPLSFFLNLGRRHKIGWNFQHMMMFSGLRGAMAFALAIRDTASYARQMMFTTTLLIVFFTVWIIGGGTTPMLSWLNIRVGVEEPSEEDQNEHHWQYFRVGVDPDQDPPPNNDSFQVLQGDGPDSARGNRTKQESAWIFRLWYSFDHNYLKPILTHSGPPLTTTLPAWCGLLARCLTSPQVYDNQEPLREEDSDFILTEGDLTLTYGDSTVTANGSSSSHTASTSLEGSRRTKSSSEEVLERDLGMGDQKVSSRGTRLVFPLEDNA
Atome Classification :
(20 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180........190.......200......---.210--........220.......230.......240.......250.......260.......270....--...280.......290.......300.......310.......320.......--330----........340.-......350...------....360.......370......--.--380.......390......----.400.......410......------.420..-.....430-.......440.......450.......460.......-470---........480...-.--...490.......500.......510.......520.......530.......540.......550.......560.......570.......580.......590.......600.......610.......620.......630.......640.......650.......660.......670.......680.......690.......700.......710.......720...
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MEPGDAARPGSGRATGAPP
P
R
L
L
L
L
P
L
L
L
GWGL
R
V
A
A
AASASSSGAAAE
D
S
S
A
M
E
E
L
A
T
E
K
E
A
E
E
S
HR
Q
D
S
V
S
L
L
T
F
I
L
L
L
T
L
T
I
L
T
I
W
L
F
KHR
R
V
R
F
L
H
E
T
G
L
A
M
I
Y
G
L
I
V
G
V
I
L
RYGTPATSGRDKSLSC
T
Q
EDR
A
F
S
T
L
L
V
NVSG
K
F
F
E
Y
T
L
KGEISPGKINSV
E
Q
N
D
M
L
R
KVTF
D
P
-
E
V
F
F
N
ILL
P
P
I
I
F
HAGY
S
L
K
K
R
H
F
F
R
N
L
---
G
S
I
---
L
A
Y
A
F
L
G
T
A
V
S
C
F
I
I
G
N
L
M
Y
G
V
V
K
L
M
K
I
M
G
Q
LSDK
F
Y
Y
T
D
C
L
F
F
G
A
I
ISATDP
V
T
V
L
A
I
F
N
E
L
HA--
D
V
D
L
Y
A
L
L
F
G
E
S
V
L
N
D
A
V
A
I
VLSS
S
I
V
A
YQPAGLNT
H
A
F
D
A
A
A
F
F
K
S
V
G
I
F
L
G
--IF-----SGS
F
T
M
G
A
VTGV-NANV
T
K
F
T
K
L
H
C
------
F
P
L
L
E
T
A
L
F
F
L
M
S
W
S
T
F
L
L
A
E
AC--
G
--
F
T
G
V
V
A
V
L
F
C
GIT
Q
A
H
Y
T
Y----NN
L
S
V
E
S
R
S
R
T
K
Q
L
F
E
V
L
H
F
------
L
A
E
N
F
I
-
F
S
Y
M
G
L
A
L
-
F
T
F
Q
K
H
VF
S
P
I
F
I
I
G
A
F
V
A
I
F
LGRA
A
H
I
Y
P
L
S
F
F
L
NL-GR----RHKIGW
N
F
Q
H
M
M
M
F
-S--G
L
R
G
A
M
A
F
A
L
A
IR
D
T
A
S
Y
A
R
Q
M
M
F
T
T
T
L
L
I
V
F
F
T
V
W
IIGGGTT
P
M
L
S
W
L
N
I
R
VGVEEPSEEDQNEH
H
W
Q
Y
F
RVGVDPDQDPPPNND
S
F
Q
V
L
QGDGPDSARGNRTKQE
S
A
W
I
F
R
L
W
YSFD
H
N
Y
L
K
P
I
LTHSGPPLTT
T
L
P
A
W
C
G
L
L
A
R
CLTSPQVYDNQEPLREEDS
D
F
I
L
TEG
D
L
T
L
T
YGD
S
T
V
T
ANGSSSSHTASTSLEGSRRTKS
S
S
E
E
V
L
E
R
DLGMGD
Q
K
VSSRG
T
R
L
V
F
PLEDNA
27
Fugue
90.15
19%
-104
- C2 -
4CZB
-
NAH1_METJA
A:
[1-415]
---------------------------------------------------------------------------------------------------------------------------
M
E
L
M
M
A
I
G
Y
L
G
L
A
L
V
L
G
S
L
V
A
K
I
A
E
K
L
K
I
P
D
I
P
L
L
L
L
L
G
L
I
I
G
P
F
L
Q
I
I
P
S
D
S
A
M
E
I
F
E
Y
A
G
P
I
G
L
I
F
I
L
L
G
G
A
F
T
M
R
I
S
L
L
K
R
V
I
---
K
T
V
---
V
R
L
D
T
I
T
F
L
I
T
L
L
I
S
G
F
I
F
N
M
V
L
N
L
---------
P
Y
T
S
P
V
G
Y
L
F
G
A
I
T
A
A
T
D
P
A
T
L
I
P
V
F
S
R
V
R
T
--
N
P
E
V
A
I
T
L
E
A
E
S
I
F
N
D
P
L
G
I
V
S
T
S
V
I
L
G
L
F
G
L
F
S
S
S
N
P
L
I
D
L
I
T
L
A
G
G
A
I
V
V
G
--
L
L
-----
L
A
K
I
Y
E
K
I
I
I
H
C
-
D
F
H
------
E
Y
V
------
A
P
L
V
L
G
G
A
M
L
L
L
Y
V
G
D
D
L
L
P
S
I
C
--
G
Y
G
F
S
G
Y
M
A
V
A
I
M
G
L
Y
L
G
D
A
L
F
----
R
A
D
D
I
-
D
Y
K
Y
I
V
S
F
C
D
D
L
S
L
------
L
A
R
V
F
I
-
F
V
F
L
G
A
C
I
----
K
L
S
M
L
E
N
Y
F
I
P
G
L
L
V
A
--
L
G
S
I
F
L
A
R
P
L
G
V
F
L
G
L
I
G
S
----
K
H
S
--
F
K
E
K
L
Y
F
A
L
-
E
--
G
P
R
G
V
V
P
A
A
L
A
V
T
V
G
I
E
I
L
K
N
A
D
K
I
P
A
S
I
T
K
Y
I
T
P
T
D
I
A
G
-
T
I
I
I
G
T
F
M
T
I
L
L
S
V
I
L
E
A
S
W
A
G
M
L
A
L
K
L
L
G
E
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
71.91
25%
-110
- C2 -
4CZA
2
?
A:
[69-310]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
L
F
T
E
G
H
N
L
S
W
R
L
L
K
K
N
M
---
P
T
I
---
V
T
L
D
T
I
G
L
I
L
T
A
L
I
A
G
F
I
F
K
V
V
F
N
S
S
F
L
L
G
F
L
-----------
F
G
A
I
I
G
A
T
D
P
A
T
L
I
P
L
F
R
Q
Y
R
V
--
K
Q
D
I
E
T
V
I
V
T
E
S
I
F
N
D
P
L
G
I
V
L
T
L
I
A
I
S
M
L
V
P
G
Y
G
G
G
I
F
S
T
L
S
--
E
K
L
G
I
Y
A
G
G
V
I
Y
F
L
Y
N
V
S
V
S
I
S
L
G
I
F
L
G
I
L
G
Y
K
F
I
K
R
T
G
I
F
D
------
F
P
E
I
E
-
A
F
S
L
S
L
A
F
L
G
F
F
I
G
E
R
L
--
D
--
A
S
G
Y
L
V
A
T
V
T
G
I
V
L
G
N
Y
K
L
LKPR
E
N
I
R
I
L
K
R
L
Q
R
A
I
E
K
E
V
-
H
F
N
D
T
L
A
A
L
A
T
I
F
I
-
F
V
L
L
G
A
E
M
-
N
L
E
V
I
W
S
N
L
G
K
G
L
L
V
A
L
G
V
M
I
L
A
R
P
L
A
T
L
P
L
L
K
W
W
N
F
-
R
E
----
Y
L
F
I
A
L
E
G
P
R
G
V
V
P
-
S
--
A
L
A
S
L
P
L
S
L
A
L
K
Y
K
S
P
L
L
T
V
H
W
G
E
I
I
M
A
T
V
V
I
T
V
L
T
S
V
I
V
E
T
L
W
I
P
I
L
K
D
K
L
D
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
71.56
25%
-113
- C2 -
4CZ9
-
?
A:
[69-310]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
L
F
T
E
G
H
N
L
S
W
R
L
L
K
K
N
M
---
P
T
I
---
V
T
L
D
T
I
G
L
I
L
T
A
L
I
A
G
F
I
F
K
V
V
F
N
S
S
F
L
L
G
F
L
-----------
F
G
A
I
I
G
A
T
D
P
A
T
L
I
P
L
F
R
Q
Y
R
V
--
K
Q
D
I
E
T
V
I
V
T
E
S
I
F
N
D
P
L
G
I
V
L
T
L
I
A
I
S
M
L
V
P
G
Y
G
G
G
I
F
S
T
L
S
--
E
K
L
G
I
Y
A
G
G
V
I
Y
F
L
Y
N
V
S
V
S
I
S
L
G
I
F
L
G
I
L
G
Y
K
F
I
K
R
T
G
I
F
D
------
F
P
E
I
E
-
A
F
S
L
S
L
A
F
L
G
F
F
I
G
E
R
L
--
D
--
A
S
G
Y
L
V
A
T
V
T
G
I
V
L
G
N
Y
K
L
LKPR
E
N
I
R
I
L
K
R
L
Q
R
A
I
E
K
E
V
-
H
F
N
D
T
L
A
A
L
A
T
I
F
I
-
F
V
L
L
G
A
E
M
-
N
L
E
V
I
W
S
N
L
G
K
G
L
L
V
A
L
G
V
M
I
L
A
R
P
L
A
T
L
P
L
L
K
W
W
N
F
-
R
E
----
Y
L
F
I
A
L
E
G
P
R
G
V
V
P
-
S
--
A
L
A
S
L
P
L
S
L
A
L
K
Y
K
S
P
L
L
T
V
H
W
G
E
I
I
M
A
T
V
V
I
T
V
L
T
S
V
I
V
E
T
L
W
I
P
I
L
K
D
K
L
D
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
70.31
25%
-113
- C2 -
4CZ8
3
?
A:
[69-310]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
L
F
T
E
G
H
N
L
S
W
R
L
L
K
K
N
M
---
P
T
I
---
V
T
L
D
T
I
G
L
I
L
T
A
L
I
A
G
F
I
F
K
V
V
F
N
S
S
F
L
L
G
F
L
-----------
F
G
A
I
I
G
A
T
D
P
A
T
L
I
P
L
F
R
Q
Y
R
V
--
K
Q
D
I
E
T
V
I
V
T
E
S
I
F
N
D
P
L
G
I
V
L
T
L
I
A
I
S
M
L
V
P
G
Y
G
G
G
I
F
S
T
L
S
--
E
K
L
G
I
Y
A
G
G
V
I
Y
F
L
Y
N
V
S
V
S
I
S
L
G
I
F
L
G
I
L
G
Y
K
F
I
K
R
T
G
I
F
D
------
F
P
E
I
E
-
A
F
S
L
S
L
A
F
L
G
F
F
I
G
E
R
L
--
D
--
A
S
G
Y
L
V
A
T
V
T
G
I
V
L
G
N
Y
K
L
LKPR
E
N
I
R
I
L
K
R
L
Q
R
A
I
E
K
E
V
-
H
F
N
D
T
L
A
A
L
A
T
I
F
I
-
F
V
L
L
G
A
E
M
-
N
L
E
V
I
W
S
N
L
G
K
G
L
L
V
A
L
G
V
M
I
L
A
R
P
L
A
T
L
P
L
L
K
W
W
N
F
-
R
E
----
Y
L
F
I
A
L
E
G
P
R
G
V
V
P
-
S
--
A
L
A
S
L
P
L
S
L
A
L
K
Y
K
S
P
L
L
T
V
H
W
G
E
I
I
M
A
T
V
V
I
T
V
L
T
S
V
I
V
E
T
L
W
I
P
I
L
K
D
K
L
D
V
G
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
67.06
26%
-105
- C2 -
4CZB
-
NAH1_METJA
A:
[123-356]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
F
G
A
I
T
A
A
T
D
P
A
T
L
I
P
V
F
S
R
V
R
T
--
N
P
E
V
A
I
T
L
E
A
E
S
I
F
N
D
P
L
G
I
V
S
T
S
V
I
L
G
L
F
--
G
L
F
S
S
S
N
P
L
I
D
L
I
T
L
A
G
--------------
G
A
I
V
V
G
L
L
L
----
A
K
I
Y
E
K
I
I
I
H
C
DFHEY
V
A
P
L
V
L
G
G
A
M
L
L
L
Y
V
G
D
D
L
L
P
S
I
C
G
Y
G
--
F
S
G
Y
M
A
V
A
I
M
G
L
Y
L
G
D
A
L
F
----
R
A
D
D
I
D
Y
K
-
Y
I
V
S
F
C
D
D
L
S
L
------
L
A
R
V
F
I
-
F
V
F
L
G
A
C
I
K
L
S
M
L
E
N
Y
F
I
P
G
L
L
V
-
A
L
G
S
I
F
L
A
R
-----
P
L
G
V
F
L
G
L
I
G
S
----
K
H
----
S
F
K
E
K
L
Y
F
-
A
L
E
G
P
R
G
V
V
P
A
A
L
A
V
T
V
G
I
E
I
L
K
N
A
D
K
I
P
A
S
I
T
K
Y
I
T
P
T
D
I
A
G
T
I
I
I
G
T
F
M
T
I
L
L
S
V
I
L
E
A
S
W
A
G
M
L
A
L
K
L
L
G
E
------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
65.48
26%
-103
- C2 -
4D0A
-
NAH1_METJA
B:
[123-356]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
F
G
A
I
T
A
A
T
D
P
A
T
L
I
P
V
F
S
R
V
R
T
--
N
P
E
V
A
I
T
L
E
A
E
S
I
F
N
D
P
L
G
I
V
S
T
S
V
I
L
G
L
F
--
G
L
F
S
S
S
N
P
L
I
D
L
I
T
L
A
G
--------------
G
A
I
V
V
G
L
L
L
----
A
K
I
Y
E
K
I
I
I
H
C
DFHEYV
A
P
L
V
L
G
G
A
M
L
L
L
Y
V
G
D
D
L
L
P
S
I
C
GY
G
--
F
S
G
Y
M
A
V
A
I
M
G
L
Y
L
G
D
A
L
F
----
R
A
D
D
I
D
Y
K
-
Y
I
V
S
F
C
D
D
L
S
L
------
L
A
R
V
F
I
-
F
V
F
L
G
A
C
I
K
L
S
M
L
E
N
Y
F
I
P
G
L
L
V
-
A
L
G
S
I
F
L
A
R
-----
P
L
G
V
F
L
G
L
I
G
S
----
K
H
----
S
F
K
E
K
L
Y
F
-
A
LE
G
P
R
G
V
V
P
A
A
L
A
V
T
V
G
I
E
I
L
K
N
A
D
K
I
P
A
S
I
T
K
Y
I
T
P
T
D
I
A
G
T
I
I
I
G
T
F
M
T
I
L
L
S
V
I
L
E
A
S
W
A
G
M
L
A
L
K
L
L
G
E
Y
K
P
K
--------------------------------------------------------------------------------------------------------------------------------------------------------------------
35
Fugue
64.21
12%
-91
* C3 *
1KPK
-
CLCA_ECOLI
A:
[12-461]
--------------------------------------------------
Q
A
A
R
L
R
R
R
Q
L
I
R
Q
L
L
E
R
D
K
T
P
L
A
I
L
F
M
A
A
V
V
G
T
L
V
G
L
A
A
V
A
F
D
K
G
V
A
W
L
Q
N
Q
R
M
G
A
L
V
H
T
A
D
N
Y
P
L
L
L
T
V
A
F
L
C
S
A
V
L
A
M
F
G
Y
F
L
V
R
K
Y
A
P
E
A
G
G
S
G
I
P
E
I
E
G
A
L
E
D
Q
R
P
V
R
W
W
R
V
L
P
V
K
F
F
G
G
L
G
T
L
G
G
-
G
M
V
L
G
R
E
G
P
T
V
Q
I
G
G
N
I
G
R
M
V
L
D
I
F
R
L
K
---
G
D
E
---
A
R
H
T
L
L
A
T
G
A
A
A
G
L
A
A
A
F
N
A
P
L
A
G
I
L
F
I
I
E
E
M
R
P
Q
F
R
Y
T
L
I
S
I
K
A
V
F
I
G
V
I
M
S
T
I
M
Y
R
I
F
N
H
E
V
A
-----------------------------
L
I
D
V
G
K
L
S
D
A
P
L
N
T
L
W
L
Y
L
I
L
G
I
I
F
G
--
I
F
-----
G
P
I
F
N
K
W
V
L
G
M
Q
-
D
L
L
H
R
V
H
G
G
N
I
T
------
K
W
V
L
M
G
G
A
I
G
G
L
C
G
L
L
G
F
V
A
P
A
T
--
S
--
G
G
G
--------------------
F
N
L
I
P
I
A
T
A
G
N
F
S
M
G
M
L
V
F
I
------
F
V
A
R
V
I
-
T
T
L
L
C
F
S
S
--
G
A
P
G
G
I
F
A
P
M
L
A
L
G
T
V
L
G
T
A
F
G
M
V
A
V
E
L
F
P
Q
Y
H
L
E
A
-
G
T
----
F
A
I
A
G
M
----
G
A
L
L
-
A
--
A
S
I
R
A
P
L
T
G
I
I
L
V
L
E
M
T
D
N
Y
Q
L
I
L
P
M
I
I
T
G
L
G
A
T
L
L
A
Q
F
T
G
G
K
P
L
Y
S
A
I
L
A
R
T
L
A
K
Q
E
A
E
Q
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
HHSearch
59.15
13%
-108
- C2 -
1ZCD
-
NHAA_ECOLI
A:
[60-351]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
-
L
W
I
N
D
A
L
M
A
V
F
F
L
L
V
G
L
E
V
K
R
E
L
M
Q
G
S
L
ASL
R
Q
A
A
F
P
V
I
A
A
I
G
G
M
I
V
P
A
L
L
Y
L
A
F
N
Y
--------------
A
-
D
P
I
T
R
E
G
W
A
I
-
P
A
A
T
D
I
A
F
A
L
G
V
L
A
L
L
G
S
RV
P
L
A
L
K
I
F
L
M
A
L
A
I
I
D
D
L
G
A
I
I
I
I
A
L
F
Y
T
N
D
L
--------
S
M
----------
A
S
--
L
G
-----
V
--
A
A
V
A
I
A
V
L
A
----
V
L
N
L
C
G
A
R
R
------
T
G
V
Y
-----
I
L
V
G
V
V
L
W
T
A
V
L
K
S
--
G
--
V
H
A
T
L
A
G
V
I
V
G
F
F
I
P
L
K
E
K
----
H
G
R
S
P
-
A
K
R
L
E
H
V
L
H
P
W
V
A
Y
------
L
I
L
P
L
F
A
F
A
N
A
G
V
S
L
-
Q
G
V
T
L
D
G
L
T
S
I
L
P
L
G
I
I
A
G
L
L
I
G
K
P
L
G
I
S
L
F
C
W
L
A
L
R
-
L
K
LAHL
P
E
G
T
T
Y
Q
Q
I
M
V
V
G
I
L
C
--
G
I
G
F
T
M
S
I
F
I
A
S
L
A
F
G
S
V
D
P
E
L
I
N
W
A
K
L
G
I
L
V
G
S
I
S
S
A
V
I
G
Y
S
W
L
R
V
R
L
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
33
Fugue
33.59
33%
203
- C2 -
1EHK
2
COXA_THET8
C:
[1-33]
-------------------------------------------------------------------
E
E
K
P
K
G
A
L
A
V
I
L
V
L
T
L
T
I
L
V
F
W
L
G
V
Y
A
V
F
F
A
R
G
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
PsiBlast_PDB
33.39
25%
28
* C4 *
4IKP
-
CARM1_HUMAN
A:
[226-286]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
D
----
L
H
R
I
E
I
P
F
K
F
H
M
L
H
-
S
--
G
L
V
H
G
L
A
F
--------------
W
F
D
V
A
F
I
G
S
I
M
T
V
W
L
S
T
A
P
T
E
P
L
T
H
W
Y
Q
V
R
C
L
F
Q
S
P
L
F
A
K
A
G
D
T
L
S
G
T
C
L
L
I
A
N
K
R
Q
S
Y
D
I
S
I
V
A
Q
V
D
Q
T
G
S
K
S
S
N
L
L
D
L
K
N
P
F
F
R
Y
----------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
33.27
25%
28
- C4 -
2V7E
-
CARM1_MOUSE
A:
[222-282]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
D
----
L
H
R
I
E
I
P
F
K
F
H
M
L
H
-
S
--
G
L
V
H
G
L
A
F
--------------
W
F
D
V
A
F
I
G
S
I
M
T
V
W
L
S
T
A
P
T
E
P
L
T
H
W
Y
Q
V
R
C
L
F
Q
S
P
L
F
A
K
A
G
D
T
L
S
G
T
C
L
L
I
A
N
K
R
Q
S
Y
D
I
S
I
V
A
Q
V
D
Q
T
G
S
K
S
S
N
L
L
D
L
K
N
P
F
F
R
-----------------------------------------------------------------------------------------------------------------------------------
14
PsiBlast_PDB
32.93
25%
34
- C4 -
2Y1W
1
CARM1_HUMAN
A:
[231-291]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
D
----
L
H
R
I
E
I
P
F
K
F
H
M
L
H
-
S
--
G
L
V
H
G
L
A
F
--------------
W
F
D
V
A
F
I
G
S
I
M
T
V
W
L
S
T
A
P
T
E
P
L
T
H
W
Y
Q
V
R
C
L
F
Q
S
P
L
F
A
K
A
G
D
T
L
S
G
T
C
L
L
I
A
N
K
R
Q
S
Y
D
I
S
I
V
A
Q
V
D
Q
T
G
S
K
S
S
N
L
L
D
L
K
N
P
F
F
R
Y
T
G
--------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
32.80
25%
38
- C4 -
3B3F
-
CARM1_RAT
A:
[227-287]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
D
----
L
H
R
I
E
I
P
F
K
F
H
M
L
H
-
S
--
G
L
V
H
G
L
A
F
--------------
W
F
D
V
A
F
I
G
S
I
M
T
V
W
L
S
T
A
P
T
E
P
L
T
H
W
Y
Q
V
R
C
L
F
Q
S
P
L
F
A
K
A
G
D
T
L
S
G
T
C
L
L
I
A
N
K
R
Q
S
Y
D
I
S
I
V
A
Q
V
D
Q
T
G
S
K
S
S
N
L
L
D
L
K
N
P
F
F
R
Y
T
---------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
32.78
25%
28
- C4 -
2V74
-
CARM1_MOUSE
B:
[222-282]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
D
----
L
H
R
I
E
I
P
F
K
F
H
M
L
H
-
S
--
G
L
V
H
G
L
A
F
--------------
W
F
D
V
A
F
I
G
S
I
M
T
V
W
L
S
T
A
P
T
E
P
L
T
H
W
Y
Q
V
R
C
L
F
Q
S
P
L
F
A
K
A
G
D
T
L
S
G
T
C
L
L
I
A
N
K
R
Q
S
Y
D
I
S
I
V
A
Q
V
D
Q
T
G
S
K
S
S
N
L
L
D
L
K
N
P
F
F
R
Y
----------------------------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
32.70
25%
36
- C4 -
3B3G
-
CARM1_RAT
A:
[366-426]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
D
----
L
H
R
I
E
I
P
F
K
F
H
M
L
H
-
S
--
G
L
V
H
G
L
A
F
--------------
W
F
D
V
A
F
I
G
S
I
M
T
V
W
L
S
T
A
P
T
E
P
L
T
H
W
Y
Q
V
R
C
L
F
Q
S
P
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
PsiBlast_PDB
32.65
25%
49
- C4 -
3B3J
2
CARM1_RAT
A:
[339-399]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
D
----
L
H
R
I
E
I
P
F
K
F
H
M
L
H
-
S
--
G
L
V
H
G
L
A
F
--------------
W
F
D
V
A
F
I
G
S
I
M
T
V
W
L
S
T
A
P
T
E
P
L
T
H
W
Y
Q
V
R
C
L
F
Q
S
P
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
PsiBlast_PDB
32.33
25%
37
- C4 -
2Y1X
1
CARM1_HUMAN
A:
[231-291]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
D
----
L
H
R
I
E
I
P
F
K
F
H
M
L
H
-
S
--
G
L
V
H
G
L
A
F
--------------
W
F
D
V
A
F
I
G
S
I
M
T
V
W
L
S
T
A
P
T
E
P
L
T
H
W
Y
Q
V
R
C
L
F
Q
S
P
L
F
A
K
A
G
D
T
L
S
G
T
C
L
L
I
A
N
K
R
Q
S
Y
D
I
S
I
V
A
Q
V
D
Q
T
G
S
K
S
S
N
L
L
D
L
K
N
P
F
F
R
Y
T
---------------------------------------------------------------------------------------------------------------------------------
31
Fugue
32.09
17%
364
* C2 *
4PAS
-
A:
[6-40]
---------------------------------------
E
E
E
K
S
R
L
L
E
K
E
N
R
E
L
E
K
I
I
A
E
K
E
E
R
V
S
E
L
R
H
Q
L
Q
S
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
34
Fugue
30.27
21%
434
- C2 -
2L9I
-
PTMA_HUMAN
A:
[2-29]
-------------------------------------------
S
D
A
A
V
D
T
S
S
E
I
T
T
K
D
L
K
E
K
K
E
V
V
E
E
A
E
N
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
29
Fugue
27.63
54%
298
- C2 -
2L0E
-
SL9A1_HUMAN
A:
[223-253]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
K
K
D
N
L
L
F
G
S
I
I
S
A
V
D
P
V
A
V
L
A
V
F
E
E
I
H
K
--
K
K
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------