@TOME V2.2
(Nov 2016)
Ref.
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : SL9A9_HUMAN: (2015-12-12 )
MERQSRVMSEKDEYQFQHQGAVELLVFNFLLILTILTIWLFKNHRFRFLHETGGAMVYGLIMGLILRYATAPTDIESGTVYDCVKLTFSPSTLLVNITDQVYEYKYKREISQHNINPHQGNAILEKMTFDPEIFFNVLLPPIIFHAGYSLKKRHFFQNLGSILTYAFLGTAISCIVIGLIMYGFVKAMIHAGQLKNGDFHFTDCLFFGSLMSATDPVTVLAIFHELHVDPDLYTLLFGESVLNDAVAIVLTYSISIYSPKENPNAFDAAAFFQSVGNFLGIFAGSFAMGSAYAIITALLTKFTKLCEFPMLETGLFFLLSWSAFLSAEAAGLTGIVAVLFCGVTQAHYTYNNLSSDSKIRTKQLFEFMNFLAENVIFCYMGLALFTFQNHIFNALFILGAFLAIFVARACNIYPLSFLLNLGRKQKIPWNFQHMMMFSGLRGAIAFALAIRNTESQPKQMMFTTTLLLVFFTVWVFGGGTTPMLTWLQIRVGVDLDENLKEDPSSQHQEANNLDKNMTKAESARLFRMWYSFDHKYLKPILTHSGPPLTTTLPEWCGPISRLLTSPQAYGEQLKEDDVECIVNQDELAINYQEQASSPCSPPARLGLDQKASPQTPGKENIYEGDLGLGGYELKLEQTLGQSQLN
Atome Classification :
(20 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.....---..130---.........140.......150.......---160---.......----------170..----------.....180.......190.......200.----......210.......220....----.--..230-...-.....240.......250...----.....260.......270.......280..-----------.....290.......300.....-.-----.310......-.320...--....-330.......340.--......350.......360..-..-.---..370....-...380-........390.......400.......410.......420.----......430.....-.--.440.......450-----.........460.......470.......480.......490.....--..500.......510.......520.......530.......540.......550.......560.......570---.........580.......590.......600.......610.......620.......630.......640...
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
M
E
R
Q
S
R
V
MSE
K
D
E
Y
Q
F
Q
HQG
A
V
E
L
L
V
F
N
F
L
L
I
L
T
I
L
T
I
W
L
FKNH
R
F
R
F
L
HETG
G
A
M
V
Y
G
L
I
M
G
L
I
L
R
YATAPTDIESG
T
V
Y
D
C
V
K
L
T
FSP
S
T
L
L
V
NI
T
D
Q
V
Y
E
Y
K
Y
K
R
E
I
S
QHNINPHQG
N
A
I
L
E
KM---TF
D
-----
P
E
I
F
F
N
VLL
P
P
I
I
F
HAGY
S
L
K
K
R
H
F
F
Q
N
L
---
G
S
I
---
L
T
Y
A
F
L
G
----------
T
A
I
S
C
----------
I
V
I
G
L
I
M
Y
G
F
V
K
A
M
I
H
AGQLKNG
D
F
H
F
T
D
----
C
L
F
F
G
S
L
MSATD
P
V
T
V
L
A
I
F
H
E
L----H--VDP
D
--
L
Y
T
-
L
L
F
G
E
S
V
L
ND
A
V
A
I
V
L
T
-
Y
S
I
----
S
I
YSPKENPN
A
F
D
A
A
A
F
F
Q
S
V
G
N
F
L
G
I
F
AG-----------SFAM
G
S
A
Y
A
I
I
T
A
L
L
T
K
F
T
K
L
CE-F-----
P
M
L
E
T
G
L
F
F
L
-
L
S
W
S
A
F
L
--
S
A
E
A-A
G
L
T
G
I
V
A
V
L
F
CGV--T
Q
A
H
Y
T
YNNLSSDSK
I
R
T
K
Q
L
-
F
E
-
F
---
M
N
F
L
A
E
N
V
I
-
F
C
Y
M
G
--
L
A
L
F
T
F
Q
N
H
I
F
N
A
L
F
I
L
G
A
F
L
A
I
F
V
A
RACNI
Y
P
L
S
F
L
L
NLGR----KQKIPW
N
F
Q
H
M
M
M
F
-S--G
L
R
G
A
I
A
F
A
L
A
I-------RNTESQP
K
Q
M
M
F
T
T
T
L
L
L
V
F
F
T
V
W
V
FGGGT
T
P
M
L
T
W
L
Q
I
R
VGVDL
D
E
--
N
LKEDPS
S
Q
H
Q
E
A
NNLDK
N
M
T
K
A
E
S
A
R
L
F
R
M
W
Y
S
F
D
H
K
Y
L
K
P
I
LTHSGPPLTTT
L
P
E
W
C
G
P
I
S
R
L
LTS
P
Q
A
Y
G
-----
E
Q
L
K
ED
D
V
E
C
I
V
N
Q
D
E
L
A
I
N
Y
Q
E
QASSPCS
P
P
A
RLGLDQKASPQTPGKENIYEGDLGLG
G
Y
E
L
K
L
E
Q
TLGQSQLN
25
Fugue
92.02
17%
-123
- C2 -
4BWZ
-
?
A:
[3-386]
------------------------------------------------------------------------------------------------------
G
A
E
H
L
L
E
I
F
Y
L
L
L
A
A
Q
V
C
A
F
I
F
K
R
L
NQP
V
V
I
-----
G
E
V
L
A
G
V
L
V
G
P
A
L
L
G
L
V
H
E
G
E
I
L
E
F
L
A
E
L
---
G
A
V
---
F
L
L
F
M
V
G
L
E
TR
L
K
D
I
L
A
V
G
K
E
A
----------
F
L
V
A
V
L
G
V
A
L
P
F
L
G
G
Y
L
Y
G
L
E
I
G
-
F
E
T
L
P
----
A
L
F
L
G
T
A
L
V
A
T
S
V
G
I
T
A
R
V
L
Q
E
L
----
G
--
V
L
S
R
--
P
Y
S
R
I
I
L
G
A
A
V
I
D
D
V
L
G
L
I
V
L
-
A
C
V
----
N
G
V
A
E
T
G
Q
V
E
----------
V
G
A
I
T
R
L
I
V
L
-----------
S
V
V
F
V
G
L
A
V
F
L
S
T
L
I
A
R
L
P
L
E
R
L
-
P
-----
V
G
S
P
L
G
F
A
L
A
-
L
G
V
G
M
A
A
--
L
A
A
S
-
I
G
L
A
P
I
V
G
A
F
L
G
G
M
L
L
S
E
V
R
E
K
Y
R
L
--------
E
E
P
I
-
F
A
-
I
---
E
S
F
L
A
-
P
I
F
-
F
A
M
V
G
--
V
R
L
---
E
L
S
A
L
A
S
P
V
V
L
V
A
G
T
V
V
T
V
I
A
I
L
G
K
V
L
G
G
F
L
G
A
L
T
Q
----
G
V
R
S
A
L
T
V
G
C
G
M
A
P
-
R
--
G
E
V
G
L
I
V
A
A
L
G
L
-------
K
A
--
G
A
V
N
E
E
E
Y
A
I
V
L
F
M
V
V
F
T
T
L
F
A
P
F
A
L
K
P
L
I
A
W
T
E
R
E
R
A
A
K
E
-------------------------------------------------------------------------------------------------------------------------------------------------------------
20
Fugue
87.39
19%
-106
- C2 -
4CZB
-
NAH1_METJA
A:
[1-415]
-------------------------------------------------------------------------------------------------------
M
E
L
M
M
A
I
G
Y
L
G
L
A
L
V
L
G
S
L
V
A
K
I
A
---
E
K
L
KIPD
I
P
L
L
L
L
L
G
L
I
I
G
P
F
L
Q
I
I
P
S
D
S
A
M
E
I
F
E
Y
A
---
G
P
I
G
--
L
I
F
I
L
L
G
----------
G
A
F
T
M
RISLLKRV
I
K
T
V
V
R
L
D
T
I
T
F
L
I
T
L
L
I
S
G
F
I
F
N
M
V
L
N
L
P
Y
TS
P
V
G
Y
L
F
G
A
I
T
A
A
T
D
P
A
T
L
I
P
V
F
S
R
V
----
R
--
T
N
P
E
--
V
A
I
-
T
L
E
A
E
S
I
F
N
D
P
L
G
I
V
S
T
-
S
V
I
L
---
G
L
F
G
L
F
S
S
S
N
P
L
I
D
L
I
T
L
A
G
G
A
I
V
V
G
L
L
L
A
-----------
K
I
Y
E
K
I
I
I
H
------
C
D
F
H
E
Y
V
A
-
P
-----
L
V
L
G
G
A
M
L
L
L
-
Y
V
G
D
D
L
L
--
P
S
I
C
G
Y
G
F
S
G
Y
M
A
V
A
I
M
G
L
--
Y
L
G
D
A
L
F
R
A
D
D
I
D
Y
K
-
Y
I
V
S
F
-
C
D
-
D
---
L
S
L
L
A
R
V
F
I
-
F
V
F
L
G
--
A
C
I
---
K
L
S
M
L
E
N
Y
F
I
P
G
L
L
V
A
L
--
G
S
I
F
L
A
R
P
L
G
V
F
L
G
L
-
I
----
G
S
K
H
S
F
K
E
K
L
Y
F
A
L
-
E
--
G
P
R
G
V
V
P
A
A
L
A
V
-------
T
V
G
I
E
I
L
K
N
A
D
K
I
P
A
S
I
T
K
Y
I
T
P
T
D
I
A
G
-
T
I
I
I
G
T
F
M
T
I
L
L
S
V
I
L
E
A
--
S
W
A
G
M
L
A
L
K
L
L
G
E
--------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
75.14
25%
-129
- C2 -
4CZB
-
NAH1_METJA
C:
[123-373]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
F
G
A
I
T
A
A
T
D
P
A
T
L
I
P
V
F
S
R
V
----
R
--
T
N
P
E
--
V
A
I
-
T
L
E
A
E
S
I
F
N
D
P
L
G
I
V
S
T
-
S
V
I
LGLF
G
L
F
S
-
S
S
N
P
-----------
L
I
D
L
I
T
L
A
G
G
-----------
A
I
V
V
G
---
L
L
L
A
K
I
Y
E
K
I
I
I
H
C
D
-
F
HEYVA
P
L
V
L
G
G
A
M
L
L
-
L
Y
V
G
D
D
L
LP
S
I
C
G
-
Y
G
F
S
G
Y
M
A
V
A
I
M
G
L
------
Y
L
G
D
A
L
F
R
A
D
D
I
D
Y
K
Y
I
-
V
S
-
F
CDD
L
S
L
L
A
R
V
F
I
-
F
V
F
L
G
AC
I
K
L
S
M
L
E
N
Y
F
I
P
G
L
L
V
--
A
L
G
S
I
F
L
A
R
P
L
G
V
----
F
L
G
L
I
G
S
----
K
H
----
S
F
K
E
K
L
Y
F
-
A
LE
G
P
R
G
V
V
P
A
A
L
A
V
TVGIEIL
K
N
A
E
K
I
P
A
S
I
T
K
Y
I
T
P
T
D
I
A
G
T
I
I
I
G
T
F
M
T
I
L
L
S
V
I
L
E
A
S
W
-----------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
72.14
25%
-138
- C2 -
4CZA
1
?
A:
[69-268]
-----------------------------------------------------------------------------------------------------------------------------------------------------
I
L
F
T
E
G
H
N
L
S
W
R
L
L
K
K
N
M
---
P
T
I
---
V
T
L
D
T
I
G
----------
L
I
L
T
A
----------
L
I
A
G
F
I
F
----
K
V
V
F
N
S
--------
S
F
L
L
----
G
F
L
F
G
A
I
I
G
A
T
D
P
A
T
L
I
P
L
F
R
Q
Y
----
R
--
V
K
Q
D
--
I
E
T
-
V
I
V
T
E
S
I
F
N
D
P
L
G
I
V
L
T
L
I
A
I
----
S
M
L
V
P
G
Y
------
G
G
G
I
F
S
T
L
S
E
K
L
G
I
Y
A
G
G
V
I
Y
F
L
Y
N
V
S
V
S
I
S
L
G
I
F
L
G
I
L
G
Y
K
F
I
K
R
T
G
I
F
D
-
F
-----
P
E
I
E
A
--
F
S
L
S
L
A
F
L
G
F
F
--
I
G
E
R
-
L
D
A
S
G
Y
L
V
A
T
V
T
G
I
--
V
L
G
N
Y
K
L
L
K
P
R
E
N
I
R
I
L
K
R
L
Q
-
R
A
-
I
---
E
K
E
V
H
F
N
D
T
-
L
A
A
L
A
--
T
I
F
I
F
V
L
L
G
A
E
M
N
L
E
V
I
W
S
N
L
G
K
G
L
L
V
A
L
G
V
M
I
L
A
R
P
L
A
T
L
P
----
L
L
K
W
W
N
F
R
E
Y
L
F
I
A
-
L
--
E
G
P
R
G
V
V
P
S
A
L
A
-------
S
L
P
L
S
L
A
L
K
Y
K
S
P
L
L
T
V
H
W
G
E
I
I
M
A
T
V
V
I
T
V
L
T
S
V
I
V
E
T
L
W
I
P
I
L
K
D
--
K
L
D
------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
70.84
24%
-125
- C2 -
4D0A
-
NAH1_METJA
B:
[123-373]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
F
G
A
I
T
A
A
T
D
P
A
T
L
I
P
V
F
S
R
V
----
R
--
T
N
P
E
--
V
A
I
-
T
L
E
A
E
S
I
F
N
D
P
L
G
I
V
S
T
-
S
V
I
LGLF
G
L
F
S
-
S
S
N
P
-----------
L
I
D
L
I
T
L
A
G
G
-----------
A
I
V
V
G
---
L
L
L
A
K
I
Y
E
K
I
I
I
H
C
D
-
F
HEYVA
P
L
V
L
G
G
A
M
L
L
-
L
Y
V
G
D
D
L
LP
S
I
C
G
-
Y
G
F
S
G
Y
M
A
V
A
I
M
G
L
------
Y
L
G
D
A
L
F
R
A
D
D
I
D
Y
K
Y
I
-
V
S
-
F
CDD
L
S
L
L
A
R
V
F
I
-
F
V
F
L
G
AC
I
K
L
S
M
L
E
N
Y
F
I
P
G
L
L
V
--
A
L
G
S
I
F
L
A
R
P
L
G
V
----
F
L
G
L
I
G
S
----
K
H
----
S
F
K
E
K
L
Y
F
-
A
LE
G
P
R
G
V
V
P
A
A
L
A
V
TVGIEIL
K
N
A
D
K
I
P
A
S
I
T
K
Y
I
T
P
T
D
I
A
G
T
I
I
I
G
T
F
M
T
I
L
L
S
V
I
L
E
A
S
W
A
G
M
L
A
L
--
K
L
L
G
E
Y
K
P
K
------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
70.16
25%
-135
- C2 -
4CZ8
1
?
A:
[69-268]
-----------------------------------------------------------------------------------------------------------------------------------------------------
I
L
F
T
E
G
H
N
L
S
W
R
L
L
K
K
N
M
---
P
T
I
---
V
T
L
D
T
I
G
----------
L
I
L
T
A
----------
L
I
A
G
F
I
F
----
K
V
V
F
N
S
--------
S
F
L
L
----
G
F
L
F
G
A
I
I
G
A
T
D
P
A
T
L
I
P
L
F
R
Q
Y
----
R
--
V
K
Q
D
--
I
E
T
-
V
I
V
T
E
S
I
F
N
D
P
L
G
I
V
L
T
L
I
A
I
----
S
M
L
V
P
G
Y
------
G
G
G
I
F
S
T
L
S
E
K
L
G
I
Y
A
G
G
V
I
Y
F
L
Y
N
V
S
V
S
I
S
L
G
I
F
L
G
I
L
G
Y
K
F
I
K
R
T
G
I
F
D
-
F
-----
P
E
I
E
A
--
F
S
L
S
L
A
F
L
G
F
F
--
I
G
E
R
-
L
D
A
S
G
Y
L
V
A
T
V
T
G
I
--
V
L
G
N
Y
K
L
L
K
P
R
E
N
I
R
I
L
K
R
L
Q
-
R
A
-
I
---
E
K
E
V
H
F
N
D
T
-
L
A
A
L
A
--
T
I
F
I
F
V
L
L
G
A
E
M
N
L
E
V
I
W
S
N
L
G
K
G
L
L
V
A
L
G
V
M
I
L
A
R
P
L
A
T
L
P
----
L
L
K
W
W
N
F
R
E
Y
L
F
I
A
-
L
--
E
G
P
R
G
V
V
P
S
A
L
A
-------
S
L
P
L
S
L
A
L
K
Y
K
S
P
L
L
T
V
H
W
G
E
I
I
M
A
T
V
V
I
T
V
L
T
S
V
I
V
E
T
L
W
I
P
I
L
K
D
--
K
L
D
V
G
----------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
70.16
25%
-134
- C2 -
4CZ9
-
?
A:
[69-268]
-----------------------------------------------------------------------------------------------------------------------------------------------------
I
L
F
T
E
G
H
N
L
S
W
R
L
L
K
K
N
M
---
P
T
I
---
V
T
L
D
T
I
G
----------
L
I
L
T
A
----------
L
I
A
G
F
I
F
----
K
V
V
F
N
S
--------
S
F
L
L
----
G
F
L
F
G
A
I
I
G
A
T
D
P
A
T
L
I
P
L
F
R
Q
Y
----
R
--
V
K
Q
D
--
I
E
T
-
V
I
V
T
E
S
I
F
N
D
P
L
G
I
V
L
T
L
I
A
I
----
S
M
L
V
P
G
Y
------
G
G
G
I
F
S
T
L
S
E
K
L
G
I
Y
A
G
G
V
I
Y
F
L
Y
N
V
S
V
S
I
S
L
G
I
F
L
G
I
L
G
Y
K
F
I
K
R
T
G
I
F
D
-
F
-----
P
E
I
E
A
--
F
S
L
S
L
A
F
L
G
F
F
--
I
G
E
R
-
L
D
A
S
G
Y
L
V
A
T
V
T
G
I
--
V
L
G
N
Y
K
L
L
K
P
R
E
N
I
R
I
L
K
R
L
Q
-
R
A
-
I
---
E
K
E
V
H
F
N
D
T
-
L
A
A
L
A
--
T
I
F
I
F
V
L
L
G
A
E
M
N
L
E
V
I
W
S
N
L
G
K
G
L
L
V
A
L
G
V
M
I
L
A
R
P
L
A
T
L
P
----
L
L
K
W
W
N
F
R
E
Y
L
F
I
A
-
L
--
E
G
P
R
G
V
V
P
S
A
L
A
-------
S
L
P
L
S
L
A
L
K
Y
K
S
P
L
L
T
V
H
W
G
E
I
I
M
A
T
V
V
I
T
V
L
T
S
V
I
V
E
T
L
W
I
P
I
L
K
D
--
K
L
D
------------------------------------------------------------------------------------------------------------------------------------------------------
29
Fugue
59.18
13%
-105
- C2 -
3ZUY
8
?
A:
[2-309]
------------------------------------------------------------------------------------------------------------------------
N
I
L
S
K
I
S
---
S
F
I
-----
G
K
T
F
S
L
W
A
A
L
F
A
A
A
A
F
F
A
P
D
T
F
K
W
A
G
P
Y
I
---
P
W
L
---
L
G
I
I
M
F
G
----------
M
G
L
T
L
----------
K
P
S
D
F
D
I
L
F
K
H
P
K
V
V
I
I
G
V
I
A
Q
F
A
I
M
P
A
T
----
A
W
L
L
S
K
L
L
N
L
P
A
E
I
A
V
G
V
I
L
V
G
C
CPGG
T
--
A
S
N
V
--
M
T
Y
-
L
A
R
G
N
V
A
L
S
V
A
V
T
S
V
S
T
-
L
I
S
----
P
L
L
T
P
A
I
F
L
M
L
A
G
E
M
L
E
I
Q
A
A
G
M
L
M
S
I
V
K
M
-----------
V
L
L
P
I
V
L
G
L
I
V
H
K
V
L
G
S
K
T
E
K
L
T
-
D
-----
A
L
P
L
V
S
V
A
A
I
-
V
L
I
I
G
A
V
--
V
G
A
S
-
K
G
K
I
M
E
S
G
L
L
I
F
A
V
--
V
V
L
H
N
G
I
G
Y
L
L
G
F
F
A
A
K
W
T
G
L
P
Y
D
-
A
---
Q
K
T
L
T
I
E
V
G
-
M
Q
N
S
G
--
L
A
A
A
L
A
A
A
H
F
A
A
A
--
P
V
V
A
V
P
G
A
L
F
S
V
W
H
N
I
S
G
S
L
L
A
T
Y
W
A
A
----
K
A
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
HHSearch
58.40
13%
-115
- C2 -
1ZCD
-
NHAA_ECOLI
A:
[61-349]
-------------------------------------------------------------------------------------------------------------------------------------------
L
W
I
N
D
A
L
M
A
V
F
F
L
L
V
G
L
E
V
K
R
E
L
M
Q
G
S
L
ASL
R
Q
A
A
F
P
V
I
A
A
I
G
G
----------
M
I
V
P
A
----------
L
L
Y
L
A
F
N
Y
---------------
A
-
D
P
I
T
----
R
E
G
W
A
I
-
P
A
A
T
D
I
A
F
A
L
G
V
L
A
L
L
----
G
SR
V
P
L
A
--
L
K
I
-
F
L
M
A
L
A
I
I
D
D
L
G
A
I
I
I
I
-
A
L
F
----
Y
T
N
D
L
-------
S
---
M
-------
A
S
L
G
V
-------------
A
A
V
A
I
A
V
L
A
V
L
N
---
L
-
C
G
A
R
R
-
T
-----
G
V
Y
-----
I
L
-
V
G
V
V
L
W
T
--
A
V
L
K
-
S
G
V
H
A
T
L
A
G
V
I
V
G
F
--
F
I
P
L
K
E
K
H
G
R
S
P
--
A
K
R
L
E
H
V
-
L
H
P
W
---
V
A
Y
L
I
L
P
L
F
A
F
A
N
A
G
--
V
S
L
Q
G
V
T
L
D
G
L
T
S
I
L
P
L
G
I
I
A
G
L
L
I
G
K
P
L
G
I
S
L
F
C
W
L
A
L
R
L
K
LAHL
P
E
G
T
T
Y
Q
Q
I
M
V
V
G
I
L
C
--
G
I
G
F
T
M
S
I
F
I
A
S
-------
L
A
F
G
S
V
D
P
E
L
I
N
W
A
K
L
G
I
L
V
G
S
I
S
S
A
V
I
G
Y
S
W
L
R
V
R
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
50.89
23%
-33
- C2 -
3ZYV
1
AOXC_MOUSE
A:
[1152-1272]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
D
I
---
F
P
Y
F
V
F
G
----------
A
A
C
S
E
----------
V
E
I
D
C
L
T
G
A
H
K
N
--
I
R
T
D
I
V
M
D
G
S
F
S
I
N
P
----
A
V
D
I
G
Q
I
E
G
A
F
V
Q
G
L
G
L
Y
T
L
E
E
L
----
K
--
Y
S
P
E
GV
L
Y
T
-
R
G
P
H
Q
Y
K
I
A
S
V
T
D
I
P
E
E
-
F
H
V
----
S
L
L
T
P
T
P
N
P
K
A
I
Y
S
S
K
G
L
G
E
A
G
T
F
L
G
C
S
V
F
-----------
F
A
I
A
A
A
V
A
A
A
R
E
E
R
W
A
I
N
S
P
A
T
A
-
E
-----
V
I
R
M
A
C
E
D
Q
F
-
T
N
L
V
P
Q
P
--
W
S
I
P
-
V
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
27
Fugue
42.86
20%
149
- C2 -
1DIP
1
T22D3_PIG
A:
[1-77]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
D
L
V
K
N
H
L
M
Y
A
VREEV
E
I
L
K
E
Q
I
R
E
L
V
E
K
N
S
Q
L
E
R
E
N
T
L
L
K
T
L
A
-
S
P
E
Q
L
E
K
F
Q
S
R
L
S
P
E
E
P
A
P
E
T
P
E
A
P
E
A
P
G
G
S
A
V
-------------
8
PsiBlast_PDB
38.44
27%
-62
- C2 -
4PYP
-
GTR1_HUMAN
A:
[52-129]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
G
E
S
I
L
P
T
T
L
T
T
L
W
S
-
L
S
V
----
A
I
F
S
V
G
G
M
I
G
S
F
S
V
G
L
F
V
N
R
F
G
R
-----
R
N
-----------
S
M
L
M
M
N
L
L
A
F
V
S
A
V
L
M
G
F
S
K
L
G
K
S
F
-----
E
M
L
I
L
G
R
F
I
I
-
G
V
Y
C
G
L
T
--
T
G
F
V
-
P
M
Y
V
G
E
V
S
P
T
A
L
R
G
--
A
L
G
T
L
H
Q
L
G
I
V
V
G
I
L
I
A
Q
V
F
G
-
L
D
-
S
---
I
M
G
N
K
D
L
W
P
-
L
L
L
S
I
--
I
F
I
P
A
L
L
Q
C
I
V
L
P
F
C
P
E
S
P
R
F
L
L
I
N
R
N
E
E
N
R
A
K
S
V
L
K
K
L
R
G
T
----
A
D
V
T
H
D
L
Q
E
M
K
E
E
S
-
R
--
Q
M
M
R
E
K
K
V
T
I
L
E
-------
L
F
R
S
P
A
Y
R
Q
P
I
L
I
A
V
V
L
Q
L
S
Q
Q
L
S
G
I
N
A
V
F
Y
Y
S
T
S
I
F
E
K
A
G
V
Q
Q
P
V
Y
--
A
T
I
G
S
G
I
V
N
T
A
F
T
V
V
S
L
F
V
V
Q
R
A
G
R
R
T
L
H
L
I
G
L
A
G
M
A
G
C
A
I
L
M
T
I
A
L
A
L
L
E
Q
L
P
W
M
S
Y
L
S
I
V
A
I
F
G
F
V
A
F
F
E
V
-----
G
P
G
P
I
P
W
F
I
V
A
E
L
F
S
Q
G
P
R
P
A
A
I
A
V
A
G
F
S
N
W
T
S
N
F
I
V
G
M
C
F
Q
Y
V
E
Q
L
C
G
P
Y
V
F
I
I
F
T
V
L
L
V
L
F
F
I
F
T
Y
F
K
V
P
E
T
-
24
Fugue
30.93
17%
340
- C2 -
2RMY
-
BIN1_HUMAN
A:
[1-34]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
A
--
E
M
G
S
K
G
V
T
A
G
K
I
A
S
N
V
Q
K
K
L
T
R
A
Q
E
K
V
L
Q
K
L
Y
-------------------------------------------------------------------------------------------------------------------------
19
HHSearch
28.41
9%
285
- C2 -
1NKZ
6
LHB5_RHOAC
B:
[4-35]
--------
T
A
E
Q
S
E
E
L
H
K
Y
V
I
D
G
T
R
V
F
L
G
L
A
L
V
A
H
F
L
A
F
S
A
T
P
W
L
H
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
Fugue
21.60
50%
321
- C3 -
1Y4E
-
SL9A1_HUMAN
A:
[155-180]
----------------------------------------------------------------------------------------------------------------------------------
F
L
Q
-----
S
D
V
F
F
L
F
L
L
P
P
I
I
L
D
A
G
Y
F
L
P
L
R
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
HHSearch
21.46
5%
594
- C2 -
2BEC
-
B:
[14-38]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
S
I
N
E
E
I
H
T
Q
F
L
D
H
L
L
T
G
I
E
D
I
C
G
H
-----------------------------------------------------------------------------------------------------------------------------------
28
Fugue
21.38
21%
476
- C2 -
1TXP
-
HNRPC_HUMAN
C:
[180-207]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
Q
--
A
I
K
K
E
L
T
Q
I
K
Q
K
V
D
S
L
L
E
N
L
E
K
I
E
K
E
-------------------------------------------------------------------------------------------------------------------------------
13
HHSearch
20.39
39%
286
- C1 -
2K3C
-
?
A:
[337-367]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
S
Y
M
A
Y
L
--
S
A
E
L
-
F
H
L
S
G
I
M
A
L
I
A
S
G
V
--
V
M
R
P
K
K
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
HHSearch
19.68
52%
275
- C2 -
2L0E
-
SL9A1_HUMAN
A:
[223-253]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
K
K
D
----
N
L
L
F
G
S
I
I
S
A
V
D
P
V
A
V
L
A
V
F
E
E
I
----
H
--
K
K
K
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
Fugue
19.60
51%
275
- C2 -
2L0E
-
SL9A1_HUMAN
A:
[223-253]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
K
K
D
----
N
L
L
F
G
S
I
I
S
A
V
D
P
V
A
V
L
A
V
F
E
E
I
----
H
--
K
K
K
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------