@TOME V2.2
(Nov 2016)
Ref.
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : SL9B1_HUMAN: (2015-12-12 )
MHTTESKNEHLEDENFQTSTTPQSLIDPNNTAQEETKTVLSDTEEIKPQTKKETYISCPLRGVLNVIITNGVILFVIWCMTWSILGSEALPGGNLFGLFIIFYSAIIGGKILQLIRIPLVPPLPPLLGMLLAGFTIRNVPFINEHVHVPNTWSSILRSIALTIILIRAGLGLDPQALRHLKVVCFRLAVGPCLMEASAAAVFSHFIMKFPWQWAFLLGFVLGAVSPAVVVPYMMVLQENGYGVEEGIPTLLMAASSMDDILAITGFNTCLSIVFSSGGILNNAIASIRNVCISLLAGIVLGFFVRYFPSEDQKKLTLKRGFLVLTMCVSAVLGSQRIGLHGSGGLCTLVLSFIAGTKWSQEKMKVQKIITTVWDIFQPLLFGLVGAEVSVSSLESNIVGISVATLSLALCVRILTTYLLMCFAGFSFKEKIFIALAWMPKATVQAVLGPLALETARVSAPHLEPYAKDVMTVAFLAILITAPNGALLMGILGPKMLTRHYDPSKIKLQLSTLEHH
Atome Classification :
(20 SA)
------.........10.....------...20........30........40....-....50....---....------60..---......70........80........90........100.......110.....-..120.......130.-..--.....140----........150....-.---..160..--...-..170......-.180--.---------------------------------..---.....190.......200.......210-..--...--...220..----.....230..---.....240.......250.....--..260.....---------..270--..--.---------....280-----------.......290.--....----..300----....------------...310......-.320.......330.......340.-......350.....---..360..----.......-----------370...----.....380.---.......390......-.400....----------...410.......420---..-------.....430.......440.......450.......460.......470.......480....--...490.......500.......510...-------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
------MHTTESKNEHLEDENF------QTSTT
P
Q
SLIDPNNT
A
Q
E
E
T
K
T
V
LS
D
T
E
E-IKPQTKKE
T
Y
---ISC
P
------
L
R
G
V
---
L
N
V
I
ITNG
V
I
L
F
V
I
W
C
M
T
W
S
I
LGSEALPGG
N
L
F
G
L
F
I
I
F
Y
S
A
I
I
G
G
K
I
L
Q
L
IRI-PLVPP
L
P
P
L
L
G
M
L
L
-
A
-
G
F
--
T
IRNVPF-----INEHVHVP
N
T
W
S
S
I
L
-
R
---
S
I
A
L
T
I
I
--
L
I
R-AGLGL
D
P
Q
A
L
R
-
H
L
K
---
V
---------------------------------
V
C
---
F
R
LAV
G
P
C
L
M
E
A
S
A
A
A
V
F
S
H
F
I
M
KFP
W
--
Q
W
--
A
F
L
--
L
G
F
V
L
GAV----
S
P
A
V
V
V
P
Y
M
M
---
V
L
QENGYGVEEG
I
P
T
L
L
M
A
ASSM--D
D
I
L
A
IT
G
F
N
---------
T
C
L
S
I
--
V
F--S---------SGG
I
L
N
N
-----------
A
I
A
S
I
R
N
V
C
I
S
--
L
L
A
G
----
I
V
L
G
F
----
F
V
R
Y------------FPSEDQ
K
K
L
T
LK-R
G
F
L
V
L
T
M
C
V
S
A
V
LGS
Q
R
IGLHGS
G
-
G
L
C
T
L
V
L
S
F
I
AGTK---W
S
Q
--
E
K
----
M
K
V
Q
K
I
I
-----------
T
-
T
V
W
D
----
I
F
Q
P
L
L
-
F
G
---
L
VGA
E
V
S
V
S
S
LESN
I
V
-
G
I
S
V
A
T
L
S
----------
L
A
L
C
V
R
I
L
T
T
Y
L
L
M
C
F---AG-------FSF
K
E
K
I
F
I
A
L
AWMP
K
A
T
V
Q
A
V
L
G
P
L
A
L
E
TARVSAPHL
E
P
Y
A
K
D
V
M
T
V
A
F
L
A
I
L
I
TAPN
G
A
L
--
L
M
GIL
G
P
K
M
L
T
RHYDP
S
K
I
K
L
Q
L
S
TLEHH-------
17
Fugue
97.00
19%
-140
- C2 -
4CZB
-
NAH1_METJA
A:
[1-415]
--------------------------------------------------------------------------------------------------------------------
M
E
L
M
M
A
I
G
Y
L
G
L
A
L
V
L
G
S
L
V
A
K
I
A
E
K
-
L
K
I
P
D
I
P
L
L
L
L
L
G
L
-
I
I
G
P
--
F
L
Q
I
I
P
-------------
S
D
S
A
M
E
I
F
-
E
Y
A
G
P
I
G
L
I
F
I
--
L
L
G
-
G
A
F
T
M
R
I
S
L
L
K
-
R
V
I
---
K
---------------------------------
T
V
---
V
R
L
D
T
I
T
F
L
I
T
L
L
I
S
G
F
I
F
N
M
V
L
N
L
P
Y
TS
P
V
--
G
Y
L
--
F
G
A
I
T
A
A
T
----
D
P
A
T
L
I
P
V
F
--------
S
R
V
R
T
N
P
E
V
A
I
T
L
E
A
E
S
I
F
--
N
D
P
L
G
I
V
S
T
S
---------
V
I
L
G
L
F
G
L
F
--
S
---------
S
S
N
P
L
I
D
-----------
L
I
T
L
A
G
G
A
I
V
V
G
L
L
L
A
K
----
I
Y
E
K
I
----
I
I
H
C
------------
D
F
H
E
Y
V
A
P
L
V
L
G
-
G
A
M
L
L
L
Y
V
G
D
D
L
L
P
S
I
C
G
Y
G
F
--
S
G
-
Y
M
A
V
A
I
M
G
L
Y
L
G
D
A
---
L
F
R
--
A
D
DID
Y
K
Y
I
V
S
F
C
-----------
D
-
D
L
S
L
----
L
A
R
V
F
I
-
F
V
---
F
L
G
A
C
I
K
L
S
M
L
E
N
Y
F
I
-
P
G
L
L
V
A
L
G
----------
S
I
F
L
A
R
P
L
G
V
F
L
G
L
I
G
---
S
K
-------
H
S
F
K
E
K
L
Y
F
A
L
E
G
-
P
R
G
V
V
P
A
A
L
A
V
T
V
G
I
E
I
L
K
N
A
D
K
I
P
A
S
I
T
K
Y
I
T
P
T
D
I
A
G
T
I
I
I
---
G
T
--
F
M
T
I
L
L
S
V
I
L
E
A
S
W
A
G
M
L
A
L
K
L
L
G
E
-----------
16
Fugue
89.24
20%
-140
- C2 -
4BWZ
-
?
A:
[3-386]
-------------------------------------------------------------------------------------------------------------------
G
A
E
H
L
L
E
I
F
Y
L
L
L
A
A
Q
V
C
A
F
I
F
K
R
L
-------
N
Q
P
V
V
I
G
E
V
L
-
A
-
G
V
--
L
V
G
--
P
A
-----
L
L
G
L
V
H
-
E
G
E
I
L
E
F
L
-
A
---
E
L
G
A
V
F
L
--
L
F
M
-
V
G
L
E
T
R
L
K
D
I
L
-
A
V
G
---
K
---------------------------------
E
A
---
F
L
V
A
V
L
G
V
A
L
P
F
L
G
G
Y
L
Y
G
L
E
I
-
G
F
E
T
--
L
P
--
A
L
F
--
L
G
T
A
L
V
A
T
----
S
V
G
I
T
A
---
R
---
V
L
Q
E
L
G
V
-
L
S
R
P
Y
S
R
I
I
L
G
A
A
V
I
--
D
D
V
L
G
L
I
V
L
A
----------
C
V
N
G
--
V
A
--
E
---------
T
G
Q
V
E
V
G
-----------
A
I
T
R
L
I
V
L
S
V
V
--
F
V
G
L
----
A
V
F
L
S
----
T
L
I
-------------------
A
R
L
P
L
E
-
R
L
P
V
G
S
P
L
G
F
A
L
A
L
G
V
G
M
A
A
L
A
A
S
I
-
G
L
A
P
I
V
G
A
F
L
G
G
M
L
---
L
S
E
VR
E
K
----
Y
R
L
E
E
P
I
-----------
F
-
A
I
E
S
----
F
L
A
P
I
F
-
F
A
---
M
V
G
V
R
L
E
L
S
A
L
A
S
P
V
V
-
L
V
A
G
T
V
V
T
----------
V
I
A
I
L
G
K
V
L
G
G
F
L
G
A
L
---
T
Q
--------
G
V
R
S
A
L
T
V
G
C
G
M
A
P
R
G
E
V
G
L
I
V
A
A
L
G
L
K
A
---
G
A
V
N
E
E
E
Y
A
I
V
L
F
M
V
V
F
T
T
L
F
A
P
F
A
L
K
P
L
--
I
A
W
T
E
R
E
R
A
A
K
E
------------------------
5
PsiBlast_PDB
84.37
23%
-144
- C2 -
4CZB
-
NAH1_METJA
A:
[64-354]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
G
L
I
F
I
--
L
L
G
-
G
A
F
T
M
R
I
S
L
L
K
-
R
V
I
---
K
---------------------------------
T
V
---
V
R
L
D
T
I
T
F
L
I
T
L
L
I
S
G
F
I
F
N
M
V
L
N
L
P
Y
--
T
S
P
V
G
Y
L
--
F
G
A
I
T
A
A
T
----
D
P
A
T
L
I
P
V
F
S
---
R
V
R
T
N
-----
P
E
V
A
I
T
L
E
A
E
S
I
F
--
N
D
P
L
G
I
V
S
T
S
---------
V
I
L
G
L
F
G
L
F
--
S
---------
S
S
N
P
L
I
D
-----------
L
I
T
L
A
G
G
A
I
V
V
G
L
L
L
A
K
----
I
Y
E
K
I
----
I
I
H
C
------------
D
F
H
E
Y
V
A
P
L
V
L
---
G
G
A
M
L
L
L
Y
V
G
D
D
L
L
P
S
I
C
G
Y
G
F
S
G
-
Y
M
A
V
A
I
M
G
L
Y
L
G
D
A
---
L
F
R
--
A
D
----
D
I
D
Y
K
Y
I
-----------
V
-
S
F
C
D
D
L
S
L
L
A
R
V
F
I
-
F
V
---
F
L
G
A
C
I
K
L
S
M
L
E
N
Y
F
I
P
G
L
L
V
A
L
G
S
----------
I
F
L
A
-
R
P
L
G
V
F
L
G
L
I
G
---
S
K
-------
H
S
F
K
E
K
L
Y
F
A
L
E
G
-
P
R
G
V
V
P
A
A
L
A
V
T
V
G
I
E
I
L
K
N
A
D
K
I
P
A
S
I
T
K
Y
I
T
P
T
D
I
A
G
T
I
I
I
G
T
F
M
T
--
I
L
L
S
V
I
L
E
A
S
W
A
G
M
L
A
L
K
L
L
G
E
--------------
18
Fugue
82.07
18%
-98
- C2 -
4QLA
1
HYEP_BOMMO
A:
[19-442]
------
L
D
L
E
E
W
W
G
P
P
E
L
K
Q
K
Q
------
D
T
S
I
K
P
F
E
-
I
T
F
S
E
T
M
V
K
E
L
K
E
R
I
K
K
R
R
P
-
F
A
P
-------------
P
------
L
E
G
V
GFK
Y
G
F
N
S
K
Q
L
D
S
W
L
K
Y
W
A
E
E
Y
P
F
A
E
R
Q
K
F
L
N
Q
Y
P
------
H
F
K
T
N
I
Q
G
L
N
I
H
F
M
R
I
T
P
K
V
P
K
G
V
E
I
V
P
L
L
L
L
H
-
G
W
PG
S
V
R
E
F
Y
E
-----
A
I
P
H
L
----
T
A
V
S
K
D
-
R
---
N
F
A
L
E
I
I
--
A
P
S
L
P
G
Y
G
F
S
D
A
A
V
R
----------------------------------------------------
P
G
L
A
A
A
E
V
A
V
I
F
K
N
L
M
A
R
L
G
Y
--
K
Q
--
Y
Y
V
--
Q
G
G
D
W
G
A
L
----
I
G
S
A
M
A
T
F
F
-----------------
P
K
--------------
E
I
I
G
F
H
---------
S
N
M
A
L
--
T
L
--
S
---------
P
A
A
T
F
L
E
-----------
F
V
G
A
L
F
---
P
S
--
L
I
V
E
----
P
E
L
A
N
----
R
L
-
Y
------------
P
L
S
E
K
Y
S
T
L
L
E
E
-
L
G
Y
M
H
I
Q
A
T
K
P
D
T
V
G
I
G
L
T
D
--
S
P
A
-
G
L
L
A
Y
I
L
E
K
F
S
T
-----
W
T
N
--
P
D
----
L
R
S
K
E
D
------------------------------
G
---
G
L
S
Y
R
W
T
K
D
Q
L
I
D
N
L
M
-
L
Y
W
-
S
T
K
S
----------
I
V
T
S
M
R
L
Y
A
E
S
F
S
S
R
H
---
F
D
-------
L
K
L
D
E
I
Q
V
Q
V
P
T
W
V
L
Q
A
K
H
E
L
A
Y
Q
P
P
C
I
L
K
M
K
--------
Y
P
K
-------
L
V
N
A
S
V
I
E
D
G
G
H
--
F
L
A
F
E
L
P
E
I
F
A
K
D
V
L
K
A
I
G
E
F
R
K
L
K
N
----------
6
PsiBlast_PDB
80.41
23%
-131
- C2 -
4D0A
-
NAH1_METJA
B:
[64-354]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
G
L
I
F
I
--
L
L
G
-
G
A
F
T
M
R
I
S
L
L
K
-
R
V
I
---
K
---------------------------------
T
V
---
V
R
L
D
T
I
T
F
L
I
T
L
L
I
S
G
F
I
F
N
M
V
L
N
L
P
Y
--
T
S
PV
G
Y
L
--
F
G
A
I
T
A
A
T
----
D
P
A
T
L
I
P
V
F
S
---
R
V
R
T
N
-----
P
E
V
A
I
T
L
E
A
E
S
I
F
--
N
D
P
L
G
I
V
S
T
S
---------
V
I
L
G
L
FG
L
F
--
S
---------
S
S
N
P
L
I
D
-----------
L
I
T
L
A
G
G
A
I
V
V
GL
L
L
A
K
----
I
Y
E
K
I
----
I
I
H
C
------------
D
F
H
E
Y
V
A
P
L
V
L
---
G
G
A
M
L
L
L
Y
V
G
D
D
L
L
P
S
I
C
G
Y
G
F
S
G
-
Y
M
A
V
A
I
M
G
L
Y
L
G
D
A
---
L
F
R
--
A
D
----
D
I
D
Y
K
Y
I
-----------
V
-
S
F
C
D
DLSL
L
A
R
V
F
I
-
F
V
---
F
L
G
A
C
I
K
L
S
M
L
E
N
Y
F
I
P
G
L
L
V
A
L
G
S
----------
I
F
L
A
-
R
P
L
G
V
F
L
G
L
I
G
---
S
K
-------
H
S
F
K
E
K
L
Y
F
A
L
E
G
-
P
R
G
V
V
P
A
A
L
A
V
T
V
G
I
E
I
L
K
N
A
D
K
I
P
A
S
I
T
K
Y
I
T
P
T
D
I
A
G
T
I
I
I
G
T
F
M
T
--
I
L
L
S
V
I
L
E
A
S
W
A
G
M
L
A
L
K
L
L
G
E
Y
K
P
K
----------
1
PsiBlast_PDB
77.02
24%
-141
- C2 -
4CZ9
-
?
A:
[59-358]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
F
V
-
R
---
V
F
G
L
V
I
I
--
L
F
T
-
E
G
H
N
L
S
W
R
L
L
K
K
N
M
P
---
T
---------------------------------
I
V
---
T
L
D
T
I
G
L
I
L
-----
T
A
L
I
A
G
F
I
F
K
V
V
F
--
N
S
--
S
F
L
--
L
G
F
L
F
G
A
I
I
GAT
D
P
A
T
L
I
P
L
F
--------
R
Q
Y
R
V
K
Q
D
I
E
T
V
I
V
T
E
S
I
F
--
N
D
P
L
G
I
V
L
T
L
---------
I
A
I
S
M
--
L
V
PG
Y
---------
G
G
G
I
F
S
T
L
S
E
K
LGI
Y
A
G
G
V
I
Y
F
L
Y
N
V
S
V
S
--
I
S
L
G
----
I
F
L
G
I
L
G
Y
K
F
I
K
R
T
GIFD-------
F
P
E
I
E
A
F
S
L
S
L
A
F
L
G
F
F
I
----------
G
E
R
--
L
D
A
S
G
-
Y
L
V
A
T
V
T
G
I
V
L
G
N
Y
KLL
K
P
R
--
E
N
----
I
R
I
L
K
R
L
Q
R
A
I
E
K
E
V
H
F
N
D
-
T
L
A
A
----
L
A
T
I
F
I
-
F
V
---
L
L
G
A
E
M
N
L
E
V
I
W
S
N
L
G
-
K
G
L
L
V
A
L
G
----------
V
M
I
L
A
R
P
L
A
T
L
P
L
L
K
W
------------
W
N
F
R
E
Y
L
F
I
A
L
E
G
P
R
G
V
V
P
S
A
L
A
S
L
P
L
S
L
A
L
K
Y
K
S
P
L
L
T
V
H
W
G
E
I
I
M
A
T
V
V
I
T
V
L
T
S
V
I
V
E
T
--
L
W
I
P
I
L
K
D
K
L
D
-------------------------
25
Fugue
67.91
11%
-110
- C1 -
3VMN
-
DEXT_STRMU
A:
[5-637]
NGNMIN
L
T
T
D
K
A
V
Y
Q
A
G
E
A
V
H
L
N
L
T
L
N
N
T
T
S
L
A
Q
N
I
T
A
T
A
E
V
Y
S
L
E
N
K
L
K
T
L
Q
Y
T
K
Y
-
L
L
P
N
E
S
Y
T
T
Q
KGE
F
V
I
P
ANSLAN
N
R
G
Y
---
L
L
K
V
N
I
S
D
S
Q
N
N
I
L
E
Q
G
N
R
A
I
A
V
E
D
D
W
R
T
F
P
R
Y
A
A
I
G
G
S
Q
K
D
--
N
N
S
V
L
T
K
N
L
P
-
D
Y
Y
R
E
L
E
Q
M
K
N
M
N
I
-
N
-
S
Y
--
F
F
Y
D
V
Y
K
SATNP
F
P
N
V
P
K
F
D
Q
S
W
N
W
W
S
H
S
---
Q
V
E
T
D
A
V
K
A
L
V
N
-
R
V
H
Q
T
G
A
V
A
M
L
-
Y
N
M
---
I
LAQNANETAVLPDTE
Y
I
Y
N
YETGGYGQNGQVM
T
Y
S
---
I
D
D
K
P
L
Q
Y
Y
Y
N
P
L
S
K
S
W
Q
N
Y
I
S
N
A
M
A
Q
--
A
M
--
K
N
G
GF
D
G
W
Q
G
D
T
I
----
G
D
N
R
V
L
S
H
N
Q
KDS
R
D
I
A
H
S
F
M
L
S
D
V
Y
A
E
F
L
N
K
M
K
E
K
L
P
Q
Y
Y
L
T
L
N
D
V
N
GENISKLAN
S
K
Q
D
V
--
I
Y
--
N
ELWPFGTSA
L
G
N
R
P
Q
E
-----------
S
Y
G
D
L
K
A
R
V
D
Q
--
V
R
Q
A
TG
K
S
L
I
V
G
A
----
Y
M
E
E
P
K
F
D
DNRIPLN
G
A
A
R
D
V
L
A
S
A
T
Y
Q
-
T
D
A
V
L
L
T
T
A
A
I
A
A
A
G
G
Y
H
M
S
L
A
A
L
A
N
P
N
D
G
G
G
V
G
V
L
E
T
A
Y
---
Y
P
T
--
Q
S
----
L
K
V
S
K
E
L
-----------
N
-
R
K
N
Y
----
H
Y
Q
Q
F
I
-
T
A
Y
E
N
L
L
R
D
K
V
E
N
D
S
A
E
P
Q
T
F
-
T
A
N
G
R
Q
L
S
QDALGINGDQ
V
W
T
Y
A
K
K
G
N
D
F
R
T
I
Q
L
---
L
N
-------
L
M
G
-----
I
T
S
D
W
K
N
E
D
G
Y
E
N
N
K
T
P
D
E
Q
T
N
L
L
V
T
Y
P
L
T
G
V
S
M
A
E
A
D
R
I
A
-
K
Q
V
Y
L
T
S
P
D
D
W
L
QS
S
M
I
S
L
A
T
Q
V
K
T
N
E
N
G
D
P
V
L
Y
I
Q
V
P
R
L
T
L
W
D
M
I
Y
I
L
E
2
PsiBlast_PDB
64.75
24%
-123
- C2 -
4CZA
2
?
A:
[101-358]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
L
I
A
G
F
I
F
K
V
V
F
--
N
S
--
S
F
L
--
L
G
F
L
F
G
A
I
I
GAT
D
P
A
T
L
I
P
L
F
--------
R
Q
Y
R
V
K
Q
D
I
E
T
V
I
V
T
E
S
I
F
--
N
D
P
L
G
I
V
L
T
L
---------
I
A
I
S
M
--
L
V
PG
Y
---------
G
G
G
I
F
S
T
L
S
E
K
LGI
Y
A
G
G
V
I
Y
F
L
Y
N
V
S
V
S
--
I
S
L
G
----
I
F
L
G
I
L
G
Y
K
F
I
K
R
TGIFD-------
F
P
E
I
E
A
F
S
L
S
L
A
F
L
G
F
F
I
----------
G
E
R
--
L
D
A
S
G
-
Y
L
V
A
T
V
T
G
I
V
L
G
N
Y
KLL
K
P
R
--
E
N
----
I
R
I
L
K
R
L
Q
R
A
I
E
K
E
V
H
F
N
D
-
T
L
A
A
----
L
A
T
I
F
I
-
F
V
---
L
L
G
A
E
M
N
L
E
V
I
W
S
N
L
G
-
K
G
L
L
V
A
L
G
----------
V
M
I
L
A
R
P
L
A
T
L
P
L
L
K
W
------------
W
N
F
R
E
Y
L
F
I
A
L
E
G
P
R
G
V
V
P
S
A
L
A
S
L
P
L
S
L
A
L
K
Y
K
S
P
L
L
T
V
H
W
G
E
I
I
M
A
T
V
V
I
T
V
L
T
S
V
I
V
E
T
--
L
W
I
P
I
L
K
D
K
L
D
-------------------------
3
PsiBlast_PDB
63.72
24%
-122
- C2 -
4CZ8
3
?
A:
[101-358]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
L
I
A
G
F
I
F
K
V
V
F
--
N
S
--
S
F
L
--
L
G
F
L
F
G
A
I
I
G
A
T
D
P
A
T
L
I
P
L
F
--------
R
Q
Y
R
V
K
Q
D
I
E
T
V
I
V
T
E
S
I
F
--
N
D
P
L
G
I
V
L
T
L
---------
I
A
I
S
M
--
L
V
PG
Y
---------
G
G
G
I
F
S
T
L
S
E
K
LGIY
A
G
G
V
I
Y
F
L
Y
N
V
S
V
S
--
I
S
L
G
----
I
F
L
G
I
L
G
Y
K
F
I
K
R
T
GIFD-------
F
P
E
I
E
A
F
S
L
S
L
A
F
L
G
F
F
I
----------
G
E
R
--
L
D
A
S
G
-
Y
L
V
A
T
V
T
G
I
V
L
G
N
Y
KLL
K
P
R
--
E
N
----
I
R
I
L
K
R
L
Q
R
A
I
E
K
E
V
H
F
N
D
-
T
L
A
A
----
L
A
T
I
F
I
-
F
V
---
L
L
G
A
E
M
N
L
E
V
I
W
S
N
L
G
-
K
G
L
L
V
A
L
G
----------
V
M
I
L
A
R
P
L
A
T
L
P
L
L
K
W
------------
W
N
F
R
E
Y
L
F
I
A
L
E
G
P
R
G
V
V
P
S
A
L
A
S
L
P
L
S
L
A
L
K
Y
K
S
P
L
L
T
V
H
W
G
E
I
I
M
A
T
V
V
I
T
V
L
T
S
V
I
V
E
T
--
L
W
I
P
I
L
K
D
K
L
D
V
G
-----------------------
4
PsiBlast_PDB
61.43
23%
-99
- C2 -
4BWZ
-
?
A:
[134-362]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
L
Q
E
L
G
V
-
L
S
R
P
Y
S
R
I
I
L
G
A
A
V
I
--
D
D
V
L
G
L
I
-
V
L
---------
A
C
V
N
G
--
V
A
--
E
---------
T
G
Q
V
E
V
G
-----------
A
I
T
--
R
L
I
V
L
S
--
V
-------
V
F
V
G
L
----
A
V
--------------
F
L
S
T
L
I
A
R
L
P
L
E
-
R
L
P
V
G
S
P
L
G
F
A
L
A
L
G
V
G
M
A
A
L
A
A
S
I
-
G
L
A
P
I
V
G
A
F
L
G
G
M
L
---
L
S
E
VR
E
K
----
Y
R
L
E
E
P
I
-----------
F
-
A
I
E
S
----
F
L
A
P
I
F
-
F
A
---
M
V
G
V
R
L
E
L
S
A
L
A
S
P
V
V
-
L
V
A
G
T
V
V
T
V
---------
I
A
I
L
G
K
V
L
G
G
F
L
G
A
L
T
---
Q
G
---------
V
R
S
A
L
T
V
G
C
G
M
A
P
R
G
E
V
G
L
I
V
A
A
L
G
L
K
A
G
A
V
N
E
---
E
E
Y
A
I
V
L
F
M
V
V
F
T
T
L
F
A
P
F
A
L
K
P
L
--
I
A
W
T
E
R
E
R
A
A
K
E
------------------------
7
HHSearch
58.98
13%
-124
- C2 -
1ZCD
-
NHAA_ECOLI
A:
[57-383]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
N
M
L
L
W
I
-
N
---
D
A
L
M
A
V
F
--
F
L
L
-
V
G
L
E
V
K
R
E
L
M
Q
-
G
S
L
ASL
R
---------------------------------
Q
A
A
F
P
V
I
A
A
I
G
G
M
I
V
P
A
L
L
Y
L
A
F
N
Y
---
A
-
D
P
--
I
T
--
R
E
G
--
W
A
I
-
P
A
A
T
----
D
I
A
F
A
L
G
V
L
A
---
L
L
G
---
S
R
V
P
L
A
L
K
I
F
L
M
A
L
A
I
I
--
D
D
L
G
A
I
I
I
I
A
---------
L
F
Y
T
N
--
D
L
--
S
------------
M
-------------------
A
S
L
G
-
V
--
A
A
V
A
----
I
A
V
L
A
----
V
L
N
L
------------
C
--
G
A
-
R
R
T
----
G
V
Y
I
--
L
V
G
V
V
L
W
T
A
V
L
K
S
G
V
H
A
---
T
L
A
G
V
I
V
G
F
F
I
P
L
K
---
E
K
H
--
G
R
S
P
A
-
K
R
L
E
H
V
L
-----------
H
P
W
V
A
Y
----
L
I
L
P
L
F
A
F
A
---
N
A
G
V
S
L
Q
G
V
T
L
D
G
L
T
S
-
I
L
P
L
G
I
I
A
----------
G
L
L
I
G
K
P
L
G
I
S
L
F
C
W
L
ALR
L
K
LAHLPEG
T
T
Y
Q
Q
I
M
V
V
G
I
L
C
G
I
G
F
T
M
S
I
F
I
A
S
L
A
F
G
S
V
D
------
P
E
L
I
N
W
A
K
L
G
I
L
V
G
S
I
S
S
A
V
I
G
Y
S
--
W
L
R
V
R
L
------------------------------
19
Fugue
38.57
15%
267
- C2 -
4JZP
1
BAP31_HUMAN
A:
[4-55]
--------
D
V
G
N
A
E
V
K
L
E
E
E
N
R
------
S
L
K
A
D
L
Q
K
L
K
D
E
L
A
S
T
K
Q
K
L
E
K
A
E
N
Q
V
L
A
M
R
K
Q
S
E
G
L
T
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
Fugue
35.10
17%
353
* C2 *
4PAS
-
A:
[6-40]
---------
E
E
E
K
S
R
L
L
E
K
E
N
R
------
E
L
E
K
I
I
A
E
K
E
E
R
V
S
E
L
R
H
Q
L
Q
S
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
Fugue
34.90
9%
235
- C2 -
2KK7
-
VATE_METJA
A:
[1-52]
------
M
A
V
K
L
M
G
V
D
K
I
K
S
K
I
L
------
D
D
A
K
A
E
A
N
K
I
I
S
E
A
E
A
E
K
A
K
I
L
E
K
A
K
E
E
A
-
E
K
R
K
A
E
I
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
Fugue
29.96
14%
270
- C2 -
2HEP
-
YNZC_BACSU
A:
[1-42]
------------------------------
M
I
S
N
A
K
I
A
R
I
N
E
L
A
A
K
A
K
A
G
V
I
T
E
E
E
K
-
A
E
Q
Q
K
L
R
Q
E
Y
---
L
K
G
F
------
R
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
HHSearch
20.65
29%
333
- C2 -
1SPF
-
PSPC_PIG
A:
[11-34]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
R
L
L
V
V
V
V
V
V
V
L
V
V
V
V
I
V
G
A
L
--
L
M
G
L
--------------------------------
15
HHSearch
20.29
30%
544
- C2 -
2KVO
-
PSB28_SYNY3
A:
[97-116]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
E
R
Y
G
A
E
N
G
L
G
F
S
K
S
E
L
E
H
H
-------
12
HHSearch
17.54
21%
290
- C2 -
2K3C
-
?
A:
[338-366]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
Y
M
A
Y
L
S
A
E
L
--
F
H
L
S
G
-
I
M
A
L
I
A
S
G
V
V
M
R
P
K
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
HHSearch
16.97
24%
293
* C3 *
2L0E
-
SL9A1_HUMAN
A:
[223-247]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
K
--
K
D
--
N
L
L
--
F
G
S
I
I
S
A
V
----
D
P
V
A
V
L
A
V
F
E
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
HHSearch
16.72
24%
218
- C2 -
3S8F
5
COXA_THET8
C:
[5-29]
---------------------------------------------------------------------------------
P
K
G
A
---
L
A
V
I
L
V
L
T
L
T
I
L
V
F
W
L
G
V
Y
A
V
F
F
A
R
G
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------