@TOME V2.2
(Nov 2016)
Ref.
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : SL9B2_HUMAN: (2015-12-12 )
MGDEDKRITYEDSEPSTGMNYTPSMHQEAQEETVMKLKGIDANEPTEGSILLKSSEKKLQETPTEANHVQRLRQMLACPPHGLLDRVITNVTIIVLLWAVVWSITGSECLPGGNLFGIIILFYCAIIGGKLLGLIKLPTLPPLPSLLGMLLAGFLIRNIPVINDNVQIKHKWSSSLRSIALSIILVRAGLGLDSKALKKLKGVCVRLSMGPCIVEACTSALLAHYLLGLPWQWGFILGFVLGAVSPAVVVPSMLLLQGGGYGVEKGVPTLLMAAGSFDDILAITGFNTCLGIAFSTGSTVFNVLRGVLEVVIGVATGSVLGFFIQYFPSRDQDKLVCKRTFLVLGLSVLAVFSSVHFGFPGSGGLCTLVMAFLAGMGWTSEKAEVEKIIAVAWDIFQPLLFGLIGAEVSIASLRPETVGLCVATVGIAVLIRILTTFLMVCFAGFNLKEKIFISFAWLPKATVQAAIGSVALDTARSHGEKQLEDYGMDVLTVAFLSILITAPIGSLLIGLLGPRLLQKVEHQNKDEEVQGETSVQV
Atome Classification :
(20 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......--140.......150.......160.......170.......180.......190.......200--...---.....210.......220.......230-..--..--....240........250.......260.......270.......280.......290--.......300.......-310.......320.......330.......340-----........350-------.......360.---......370.....--...380----.......390...---.....400........410.-.....-.420...--....430.......440---..-------.....450.......460......-.470.......480----.---------..--......490.......500--.........510.......520.......530.....
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MGDED
K
R
I
T
YEDSEPSTGMNYT
P
S
M
H
Q
E
A
Q
E
E
T
V
M
K
L
KGIDANEPTE
G
S
I
L
L
KSS
E
K
K
L
QETPT
E
A
N
H
V
Q
R
L
R
Q
M
LACPP
H
G
L
L
D
R
V
I
T
N
V
T
I
I
V
L
L
W
A
V
V
W
SITGSECLPGG
N
L
F
G
I
I
I
L
F
Y
C
A
I
IGG
K
L
L
G
L
I
KLPT--LP
P
L
P
S
L
L
G
M
L
L
A
G
F
L
I
RNIPVIND
N
V
Q
I
K
H
K
W
S
S
S
L
R
S
I
A
L
S
I
I
L
V
RAGLGL
D
S
K
A
L
K
K
L
K
---
G
V
C
---
V
R
LSMG
P
C
I
V
E
A
C
T
S
A
L
L
A
H
Y
L
LGLP
W
--
Q
W
--
G
F
--
I
L
G
F
V
L
-GAV
S
P
A
V
V
V
P
S
M
L
L
LQGGGYGVEKGV
P
T
L
L
M
AAGSFD
D
I
L
A
ITGFNT
C
L
G
I
--
A
FST
G
S
T
V
F
N
V
L
R
G
V
L
E
-
V
V
I
G
VA
T
G
S
V
L
G
F
F
I
Q
YFPSRDQ
D
K
L
V
C
K
R
T
F
------
L
V
L
G
L
S
V
L
A
V
F
-------
S
S
VHFGFPGSG---
G
L
C
T
L
V
M
A
-
F
L
AGM--GWT
S
E
K
----
A
E
V
E
K
I
I
A
V
-
A
W
D
---
I
F
Q
P
L
L
-
F
G
L
IGA
E
V
S
I
A
SL-RP
E
T
V
-
G
L
C
V
A
T
V
--
G
I
A
V
L
I
R
I
L
T
T
F
L
M
V
C
F---AG-------FNL
K
E
K
I
F
I
S
F
AWL
P
K
A
T
V
Q
A
A
I
G
-
S
V
A
L
D
T
A
R
SH
G
E
------
K
---------
Q
L
--
E
D
YG
M
D
V
L
T
V
A
F
L
S
I
L
I
----TA
P
I
G
S
L
L
I
G
LL
G
P
R
L
L
Q
K
V
EHQNK
D
E
EVQGETSVQV
30
Fugue
95.48
19%
-110
- C3 -
4CZB
-
NAH1_METJA
A:
[1-415]
-------------------------------
M
E
L
M
M
A
I
G
Y
L
G
L
A
L
V
L
G
S
L
V
A
K
I
A
E
K
-----------------------------------------------------------------------------
L
K
I
P
D
--
I
P
L
L
--
L
L
L
G
L
I
I
G
P
F
L
Q
I
I
P
-----
S
D
S
A
M
E
I
F
E
Y
A
G
P
I
G
L
I
F
I
L
L
G
G
A
F
T
M
R
I
S
L
L
K
R
V
I
---
K
T
V
---
V
R
L
D
T
I
T
F
L
I
T
L
L
I
S
G
F
I
F
N
M
V
L
N
L
P
Y
TS
P
V
--
G
Y
--
L
F
G
A
I
T
-
A
A
T
D
P
A
T
L
I
P
V
F
-----
S
R
V
R
T
N
P
E
V
A
I
T
L
E
A
E
S
I
F
N
D
P
L
G
I
V
S
T
S
V
I
L
G
L
F
G
L
F
S
S
S
N
P
L
I
D
L
I
T
L
A
G
G
A
I
V
V
G
L
L
L
A
K
I
Y
E
K
I
I
I
H
C
D
F
H
E
Y
V
A
P
L
V
L
G
G
A
------
M
L
L
L
Y
V
G
D
D
L
L
-------
P
S
I
C
-
G
Y
G
F
S
G
---
Y
M
A
V
A
I
M
G
-
L
Y
L
G
D
--
A
L
F
R
A
D
DID
Y
K
Y
I
V
S
F
C
D
D
-
L
S
L
---
L
A
R
V
F
I
-
F
V
F
L
G
A
C
I
K
L
S
M
L
-
E
N
Y
F
I
-
P
G
L
L
V
A
L
--
G
S
I
F
L
A
R
P
L
G
V
F
L
G
L
I
G
---
S
K
-------
H
S
F
K
E
K
L
Y
F
A
L
E
G
-
P
R
G
V
V
P
A
A
L
A
-
V
T
V
G
I
E
I
L
K
N
A
D
------
K
---------
I
P
--
A
S
I
T
K
Y
I
T
P
T
D
I
A
G
T
I
I
----
I
G
T
F
M
T
I
L
L
S
V
I
L
E
A
S
W
A
G
M
L
A
L
K
L
L
G
E
---------
28
Fugue
89.01
20%
-114
- C3 -
4BWZ
-
?
A:
[3-386]
---------------------------------------------------------------
G
A
E
H
L
L
E
I
F
Y
L
L
L
A
A
Q
V
C
A
F
I
F
K
R
L
N
Q
P
V
V
I
G
E
V
L
A
G
V
L
V
---
G
P
A
L
L
G
L
V
H
E
G
E
I
L
E
F
L
A
E
L
G
A
V
F
L
L
F
M
V
G
L
E
T
R
L
K
D
I
L
A
V
G
K
E
A
F
L
V
A
V
L
G
V
A
L
P
F
L
G
G
Y
L
Y
G
L
E
I
G
F
E
T
L
P
A
L
F
L
G
T
A
L
V
A
T
S
V
G
I
T
A
R
V
L
Q
E
L
----
G
V
---------------------------------------------------------------------
L
S
R
P
Y
S
R
I
I
L
G
A
A
V
I
D
D
V
L
G
L
I
V
L
A
C
V
N
G
V
--
A
E
T
G
Q
V
E
V
G
A
I
T
R
L
I
V
L
-
S
V
V
F
V
G
L
A
V
F
L
S
T
L
I
A
R
L
P
L
E
R
L
P
V
G
S
P
L
G
F
A
------
L
A
L
G
V
G
M
A
A
L
A
-------
A
S
I
-----------
G
L
A
P
I
V
G
A
-
F
L
G
G
M
L
L
S
E
V
R
E
K
----
Y
R
L
E
E
P
I
F
A
-
I
E
S
---
F
L
A
P
I
F
-
F
A
M
V
G
V
R
L
E
L
S
A
L
A
S
P
V
V
L
-
V
A
G
T
V
V
T
--
V
I
A
I
L
G
K
V
L
G
G
F
L
G
A
L
T
---
Q
G
---------
V
R
S
A
L
T
V
G
C
G
M
A
P
R
G
E
V
G
L
I
V
A
-
A
L
G
L
K
A
----
G
A
------
V
---------
N
E
--
E
E
Y
A
I
V
L
F
M
V
V
F
T
T
L
F
A
----
P
F
A
L
K
P
L
I
A
W
T
E
R
E
R
A
A
K
E
------------------
4
PsiBlast_PDB
85.26
21%
-133
- C3 -
4CZB
-
NAH1_METJA
C:
[64-404]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
G
L
I
F
I
L
L
G
G
A
F
T
M
R
I
S
L
L
K
R
V
I
---
K
T
V
---
V
R
L
D
T
I
T
F
L
I
T
L
L
I
S
G
F
I
F
N
M
V
L
N
L
P
Y
--
T
S
PV
G
Y
--
L
F
G
A
I
T
-
A
A
T
D
P
A
T
L
I
P
V
F
S
R
V
R
-----
T
N
P
E
V
A
I
T
L
E
A
E
S
I
F
N
D
P
L
G
I
V
S
T
S
V
I
L
G
L
FG
L
F
S
S
S
N
P
L
I
D
---------
L
I
T
L
A
G
G
A
I
V
---
V
G
L
L
L
A
K
I
Y
E
K
I
I
I
H
C
D
F
HEYVAP
L
V
L
G
G
A
M
L
L
L
Y
VGDDLLP
S
I
C
G
Y
G
F
--
S
G
---
Y
M
A
V
A
I
M
G
L
Y
L
G
D
A
--
L
F
R
A
D
D
----
I
D
Y
K
Y
I
V
S
F
-
C
D
D
LSL
L
A
R
V
F
I
-
F
V
F
L
G
A
C
I
K
L
S
M
L
-
E
N
Y
F
I
P
G
L
L
V
A
-
L
--
G
S
I
F
L
A
R
P
L
G
V
F
L
G
L
I
G
---
S
K
-------
H
S
F
K
E
K
L
Y
F
A
L
E
G
-
P
R
G
V
V
P
A
A
L
A
-
V
T
V
G
I
E
I
L
K
N
A
E
------
K
IPASITKYI
T
P
--
T
D
I
A
G
T
I
I
I
G
T
F
M
T
I
L
L
----
S
V
I
L
E
A
S
W
-----------------------------
5
PsiBlast_PDB
85.03
21%
-126
- C3 -
4D0A
-
NAH1_METJA
B:
[64-419]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
G
L
I
F
I
L
L
G
G
A
F
T
M
R
I
S
L
L
K
R
V
I
---
K
T
V
---
V
R
L
D
T
I
T
F
L
I
T
L
L
I
S
G
F
I
F
N
M
V
L
N
L
P
Y
--
T
S
PV
G
Y
--
L
F
G
A
I
T
-
A
A
T
D
P
A
T
L
I
P
V
F
S
R
V
R
-----
T
N
P
E
V
A
I
T
L
E
A
E
S
I
F
N
D
P
L
G
I
V
S
T
S
V
I
L
G
L
FG
L
F
S
S
S
N
P
L
I
D
---------
L
I
T
L
A
G
G
A
I
V
---
V
G
L
L
L
A
K
I
Y
E
K
I
I
I
H
C
D
F
HEYVAP
L
V
L
G
G
A
M
L
L
L
Y
VGDDLLP
S
I
C
G
Y
G
F
--
S
G
---
Y
M
A
V
A
I
M
G
L
Y
L
G
D
A
--
L
F
R
A
D
D
----
I
D
Y
K
Y
I
V
S
F
-
C
D
D
LSL
L
A
R
V
F
I
-
F
V
F
L
G
A
C
I
K
L
S
M
L
-
E
N
Y
F
I
P
G
L
L
V
A
-
L
--
G
S
I
F
L
A
R
P
L
G
V
F
L
G
L
I
G
---
S
K
-------
H
S
F
K
E
K
L
Y
F
A
L
E
G
-
P
R
G
V
V
P
A
A
L
A
V
T
V
G
I
E
I
L
K
N
A
D
K
IPASIT
K
---------
Y
I
TP
T
D
I
A
G
T
I
I
I
G
T
F
M
T
I
L
L
----
S
V
I
L
E
A
S
W
A
G
M
L
A
L
K
L
L
G
E
Y
K
P
K
--------------
32
Fugue
69.89
15%
-88
- C1 -
4CWU
-
CAPSP_ADE05
N:
[52-569]
----
R
N
S
I
R
Y
S
E
L
A
P
L
F
D
T
T
R
V
Y
L
V
D
N
K
S
T
D
V
A
S
L
N
Y
Q
N
D
H
S
N
F
L
T
---
T
V
I
Q
N
N
D
Y
S
P
G
E
A
S
T
Q
T
I
N
L
D
D
R
S
H
W
------------------------------------
G
G
D
L
K
T
I
L
--------------
H
T
N
M
P
N
--
V
N
E
F
M
-
F
T
N
K
F
K
A
R
V
M
V
S
R
L
P
T
K
D
N
Q
V
E
L
K
Y
E
W
V
E
---------
F
T
L
P
E
G
N
Y
S
E
T
M
T
I
D
L
M
N
---
N
A
I
---
V
E
H
Y
L
K
V
G
R
Q
N
G
V
L
E
S
D
I
G
V
K
F
D
T
R
N
F
--
R
L
--
G
F
DP
V
T
G
L
V
M
P
G
V
Y
T
N
E
A
F
H
P
D
I
I
L
L
P
G
C
G
V
D
F
T
H
S
R
L
S
N
L
L
------
G
I
R
K
R
Q
P
F
Q
E
G
F
R
I
--
T
Y
D
------
D
L
E
G
G
N
I
P
-
A
L
L
D
V
D
A
Y
Q
A
S
L
K
K
P
V
I
K
P
L
T
E
D
S
K
---
K
R
S
Y
N-----
L
I
S
N
D
S
T
F
T
Q
Y
-------
R
S
W
Y
L
A
Y
N
Y
G
D
PQT
G
I
R
S
W
T
L
L
-
C
T
P
D
V
--
T
C
G
S
E
Q
----
V
Y
----
W
S
L
-
P
D
M
---
M
Q
D
P
V
T
-
F
R
S
T
R
Q
I
S
N
F
P
V
V
-
G
A
E
L
L
-
P
V
H
S
K
S
F
YN
D
Q
A
V
Y
S
Q
L
I
R
Q
F
T
S
L
T
H
---
V
F
-------
N
R
F
P
E
N
Q
I
L
A
R
P
P
A
P
T
I
T
T
V
S
E
-----
N
V
P
A
L
T
D
H
G
T
------
L
---------
P
L
--
R
N
---
S
I
G
G
V
Q
R
V
T
I
T
D
ARRR
T
C
P
Y
V
Y
K
A
L
G
I
V
S
P
R
V
L
S
S
R
-----------------
18
HHSearch
57.15
13%
-112
- C3 -
1ZCD
-
NHAA_ECOLI
A:
[57-384]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
N
M
L
L
W
I
N
D
A
L
M
A
V
F
F
L
L
V
G
L
E
V
K
R
E
L
M
Q
G
S
L
ASL
R
Q
A
A
F
P
V
I
A
A
I
G
G
M
I
V
P
A
L
L
Y
L
A
F
N
Y
---
A
-
D
P
--
I
T
--
R
E
--
G
W
A
I
-
P
-
A
A
T
D
I
A
F
A
L
G
V
L
---
A
L
L
G
S
R
V
P
L
A
L
K
I
F
L
M
A
L
A
I
I
D
D
L
G
A
I
I
I
I
A
L
F
Y
T
N
--
D
L
S
----
M
-------
A
S
-
L
G
-
V
A
A
V
A
I
A
V
L
A
V
L
N
L
C
G
--
A
R
---
R
T
G
V
Y
-------
I
--
L
V
G
V
V
L
W
T
-------
A
V
L
K
S
G
V
--
H
A
---
T
L
A
G
V
I
V
G
-
F
F
I
P
L
--
K
E
K
H
G
R
S
P
A
-
K
R
L
E
H
V
L
H
P
W
V
A
Y
---
L
I
L
P
L
F
A
F
A
N
A
G
V
S
L
Q
G
V
T
L
-
D
G
L
T
S
-
I
L
P
L
G
I
I
--
A
G
L
L
I
G
K
P
L
G
I
S
L
F
C
W
L
ALR
L
K
LAHLPEG
T
T
Y
Q
Q
I
M
V
V
G
I
L
C
G
I
G
F
T
M
S
I
F
I
A
-
S
L
A
F
G
S
V
----------------------
D
--
P
E
L
I
N
W
A
K
L
G
I
L
V
G
S
I
S
----
S
A
V
I
G
Y
S
W
L
R
V
R
L
------------------------
2
PsiBlast_PDB
48.82
27%
-124
- C3 -
4CZA
1
?
A:
[52-163]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
L
A
H
E
I
F
D
F
V
R
V
F
G
L
V
I
I
L
F
T
E
G
H
N
L
S
W
R
L
L
K
K
N
M
---
P
T
I
---
V
T
L
D
T
I
G
L
I
L
T
A
L
I
A
G
F
I
F
K
V
V
F
N
S
S
F
--
L
L
--
G
F
--
L
F
G
A
I
I
-
G
A
T
D
P
A
T
L
I
P
--
L
F
R
Q
---
Y
R
V
K
Q
D
I
E
T
V
I
V
T
E
S
I
F
N
D
P
L
G
I
V
L
T
L
I
A
I
S
M
--
L
V
P
G
Y
G
G
G
I
F
S
T
L
S
E
K
L
-
G
I
Y
A
G
G
V
I
Y
F
L
Y
N
V
S
V
S
I
S
L
G
I
F
L
G
I
L
G
Y
K
F
I
------
K
R
T
G
I
F
D
F
P
E
I
-------
E
A
F
S
L
S
L
A
F
L
G
---
F
F
I
G
E
R
L
D
-
A
S
G
Y
L
--
V
A
T
V
T
G
----
I
V
L
G
N
Y
K
L
L
-
K
P
R
---
E
N
I
R
I
L
-
K
R
L
Q
R
A
I
E
K
E
V
H
F
-
N
D
T
L
A
-
A
L
A
T
I
F
I
--
F
V
L
L
G
A
E
M
N
L
E
V
I
W
S
N
L
---
G
K
-------
G
L
L
V
A
L
G
V
M
I
L
A
R
P
L
A
T
L
P
L
L
K
W
W
-
N
F
R
E
Y
L
F
I
A
L
E
G
------
P
---------
R
G
--
V
V
P
S
A
L
A
S
L
P
L
S
L
A
L
K
Y
----
K
S
P
L
L
T
V
H
W
G
E
I
I
M
A
T
V
V
I
T
V
L
T
S
V
I
V
E
T
L
W
I
P
I
L
K
D
1
PsiBlast_PDB
48.64
27%
-123
- C3 -
4CZ8
2
?
A:
[52-163]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
L
A
H
E
I
F
D
F
V
R
V
F
G
L
V
I
I
L
F
T
E
G
H
N
L
S
W
R
L
L
K
K
N
M
---
P
T
I
---
V
T
L
D
T
I
G
L
I
L
T
A
L
I
A
G
F
I
F
K
V
V
F
N
S
S
F
--
L
L
--
G
F
--
L
F
G
A
I
I
-
G
A
T
D
P
A
T
L
I
P
--
L
F
R
Q
---
Y
R
V
K
Q
D
I
E
T
V
I
V
T
E
S
I
F
N
D
P
L
G
I
V
L
T
L
I
A
I
S
M
--
L
V
P
G
Y
G
G
G
I
F
S
T
L
S
E
K
L
-
G
I
Y
A
G
G
V
I
Y
F
L
Y
N
V
S
V
S
I
S
L
G
I
F
L
G
I
L
G
Y
K
F
I
------
K
R
T
G
I
F
D
F
P
E
I
-------
E
A
F
S
L
S
L
A
F
L
G
---
F
F
I
G
E
R
L
D
-
A
S
G
Y
L
--
V
A
T
V
T
G
----
I
V
L
G
N
Y
K
L
L
-
K
P
R
---
E
N
I
R
I
L
-
K
R
L
Q
R
A
I
E
K
E
V
H
F
-
N
D
T
L
A
-
A
L
A
T
I
F
I
--
F
V
L
L
G
A
E
M
N
L
E
V
I
W
S
N
L
---
G
K
-------
G
L
L
V
A
L
G
V
M
I
L
A
R
P
L
A
T
L
P
L
L
K
W
W
-
N
F
R
E
Y
L
F
I
A
L
E
G
------
P
---------
R
G
--
V
V
P
S
A
L
A
S
L
P
L
S
L
A
L
K
Y
----
K
S
P
L
L
T
V
H
W
G
E
I
I
M
A
T
V
V
I
T
V
L
T
S
V
I
V
E
T
L
W
I
P
I
L
K
D
3
PsiBlast_PDB
47.25
27%
-123
- C3 -
4CZ9
-
?
A:
[52-163]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
L
A
H
E
I
F
D
F
V
R
V
F
G
L
V
I
I
L
F
T
E
G
H
N
L
S
W
R
L
L
K
K
N
M
---
P
T
I
---
V
T
L
D
T
I
G
L
I
L
T
A
L
I
A
G
F
I
F
K
V
V
F
N
S
S
F
--
L
L
--
G
F
--
L
F
G
A
I
I
-
G
A
T
D
P
A
T
L
I
P
--
L
F
R
Q
---
Y
R
V
K
Q
D
I
E
T
V
I
V
T
E
S
I
F
N
D
P
L
G
I
V
L
T
L
I
A
I
S
M
--
L
V
P
G
Y
G
G
G
I
F
S
T
L
S
E
K
L
-
G
I
Y
A
G
G
V
I
Y
F
L
Y
N
V
S
V
S
I
S
L
G
I
F
L
G
I
L
G
Y
K
F
I
------
K
R
T
G
I
F
D
F
P
E
I
-------
E
A
F
S
L
S
L
A
F
L
G
---
F
F
I
G
E
R
L
D
-
A
S
G
Y
L
--
V
A
T
V
T
G
----
I
V
L
G
N
Y
K
L
L
-
K
P
R
---
E
N
I
R
I
L
-
K
R
L
Q
R
A
I
E
K
E
V
H
F
-
N
D
T
L
A
-
A
L
A
T
I
F
I
--
F
V
L
L
G
A
E
M
N
L
E
V
I
W
S
N
L
---
G
K
-------
G
L
L
V
A
L
G
V
M
I
L
A
R
P
L
A
T
L
P
L
L
K
W
W
-
N
F
R
E
Y
L
F
I
A
L
E
G
------
P
---------
R
G
--
V
V
P
S
A
L
A
S
L
P
L
S
L
A
L
K
Y
----
K
S
P
L
L
T
V
H
W
G
E
I
I
M
A
T
V
V
I
T
V
L
T
S
V
I
V
E
T
L
W
I
P
I
L
K
D
16
PsiBlast_CBE
39.16
32%
-24
- C3 -
3PZR
1
DHAS1_VIBCH
B:
[217-282]
----------------------------------------------------------------------------------------------------------------------------------------------------
F
G
V
P
L
A
G
S
L
I
P
W
I
D
V
K
R
D
N
G
Q
S
K
E
E
W
K
A
G
V
E
A
N
K
I
--------
L
G
L
Q
D
S
P
V
-
P
I
D
---
G
T
C
---
V
R
I
G
A
M
R
C
H
S
Q
A
L
T
I
K
L
K
Q
N
I
P
L
D
E
I
E
--
E
M
--
I
A
--
T
H
N
D
W
V
-
K
V
I
P
N
E
R
D
I
T
A
R
E
L
T
P
A
K
V
T
G
T
L
S
V
P
V
G
R
L
R
K
M
A
M
G
D
D
F
L
N
A
F
T
V
G
D
Q
L
L
W
--
G
A
A
E
P
L
R
R
T
L
R
I
I
L
A
E
K
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
39.01
32%
-27
- C3 -
3PZR
1
DHAS1_VIBCH
A:
[217-282]
----------------------------------------------------------------------------------------------------------------------------------------------------
F
G
V
P
L
A
G
S
L
I
P
W
I
D
V
K
R
D
N
G
Q
S
K
E
E
W
K
A
G
V
E
A
N
K
I
--------
L
G
L
Q
D
S
P
V
-
P
I
D
---
G
T
C
---
V
R
I
G
A
M
R
C
H
S
Q
A
L
T
I
K
L
K
Q
N
I
P
L
D
E
I
E
--
E
M
--
I
A
--
T
H
N
D
W
V
-
K
V
I
P
N
E
R
D
I
T
A
R
E
L
T
P
A
K
V
T
G
T
L
S
V
P
V
G
R
L
R
K
M
A
M
G
D
D
F
L
N
A
F
T
V
G
D
Q
L
L
W
--
G
A
A
E
P
L
R
R
T
L
R
I
I
L
A
E
K
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
PsiBlast_CBE
38.17
32%
-19
- C3 -
1MB4
1
DHAS1_VIBCH
B:
[217-282]
----------------------------------------------------------------------------------------------------------------------------------------------------
F
G
V
P
L
A
G
S
L
I
P
W
I
D
V
K
R
D
N
G
Q
S
K
E
E
W
K
A
G
V
E
A
N
K
I
--------
L
G
L
Q
D
S
P
V
-
P
I
D
---
G
T
C
---
V
R
I
G
A
M
R
C
H
S
Q
A
L
T
I
K
L
K
Q
N
I
P
L
D
E
I
E
--
E
M
--
I
A
--
T
H
N
D
W
V
-
K
V
I
P
N
E
R
D
I
T
A
R
E
L
T
P
A
K
V
T
G
T
L
S
V
P
V
G
R
L
R
K
M
A
M
G
D
D
F
L
N
A
F
T
V
G
D
Q
L
L
W
--
G
A
A
E
P
L
R
R
T
L
R
I
I
L
A
E
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
PsiBlast_CBE
37.66
32%
-26
- C3 -
3Q0E
1
DHAS1_VIBCH
B:
[217-282]
----------------------------------------------------------------------------------------------------------------------------------------------------
F
G
V
P
L
A
G
S
L
I
P
W
I
D
V
K
R
D
N
G
Q
S
K
E
E
W
K
A
G
V
E
A
N
K
I
--------
L
G
L
Q
D
S
P
V
-
P
I
D
---
G
T
C
---
V
R
I
G
A
M
R
C
H
S
Q
A
L
T
I
K
L
K
Q
N
I
P
L
D
E
I
E
--
E
M
--
I
A
--
T
H
N
D
W
V
-
K
V
I
P
N
E
R
D
I
T
A
R
E
L
T
P
A
K
V
T
G
T
L
S
V
P
V
G
R
L
R
K
M
A
M
G
D
D
F
L
N
A
F
T
V
G
D
Q
L
L
W
--
G
A
A
E
P
L
R
R
T
L
R
I
I
L
A
E
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
37.34
32%
-23
- C3 -
1MB4
1
DHAS1_VIBCH
A:
[217-282]
----------------------------------------------------------------------------------------------------------------------------------------------------
F
G
V
P
L
A
G
S
L
I
P
W
I
D
V
K
R
D
N
G
Q
S
K
E
E
W
K
A
G
V
E
A
N
K
I
--------
L
G
L
Q
D
S
P
V
-
P
I
D
---
G
T
C
---
V
R
I
G
A
M
R
C
H
S
Q
A
L
T
I
K
L
K
Q
N
I
P
L
D
E
I
E
--
E
M
--
I
A
--
T
H
N
D
W
V
-
K
V
I
P
N
E
R
D
I
T
A
R
E
L
T
P
A
K
V
T
G
T
L
S
V
P
V
G
R
L
R
K
M
A
M
G
D
D
F
L
N
A
F
T
V
G
D
Q
L
L
W
--
G
A
A
E
P
L
R
R
T
L
R
I
I
L
A
E
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
31
Fugue
37.30
16%
180
- C3 -
1DEB
-
APC_HUMAN
A:
[1-54]
--------------------------
A
A
A
S
Y
D
Q
L
L
K
Q
V
E
A
L
K
M
E
N
S
N
L
R
Q
E
L
E
D
N
S
N
H
L
T
K
L
E
T
E
A
S
N
M
K
E
V
L
K
Q
L
Q
G
S
I
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
37.28
32%
-25
- C3 -
3Q0E
1
DHAS1_VIBCH
A:
[217-282]
----------------------------------------------------------------------------------------------------------------------------------------------------
F
G
V
P
L
A
G
S
L
I
P
W
I
D
V
K
R
D
N
G
Q
S
K
E
E
W
K
A
G
V
E
A
N
K
I
--------
L
G
L
Q
D
S
P
V
-
P
I
D
---
G
T
C
---
V
R
I
G
A
M
R
C
H
S
Q
A
L
T
I
K
L
K
Q
N
I
P
L
D
E
I
E
--
E
M
--
I
A
--
T
H
N
D
W
V
-
K
V
I
P
N
E
R
D
I
T
A
R
E
L
T
P
A
K
V
T
G
T
L
S
V
P
V
G
R
L
R
K
M
A
M
G
D
D
F
L
N
A
F
T
V
G
D
Q
L
L
W
--
G
A
A
E
P
L
R
R
T
L
R
I
I
L
A
E
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
37.17
32%
-15
- C3 -
1MC4
-
DHAS1_VIBCH
A:
[217-282]
----------------------------------------------------------------------------------------------------------------------------------------------------
F
G
V
P
L
A
G
S
L
I
P
W
I
D
V
K
R
D
N
G
Q
S
K
E
E
W
K
A
G
V
E
A
N
K
I
--------
L
G
L
Q
D
S
P
V
-
P
I
D
---
G
T
C
---
V
R
I
G
A
M
R
C
H
S
Q
A
L
T
I
K
L
K
Q
N
I
P
L
D
E
I
E
--
E
M
--
I
A
--
T
H
N
D
W
V
-
K
V
I
P
N
E
R
D
I
T
A
R
E
L
T
P
A
K
V
T
G
T
L
S
V
P
V
G
R
L
R
K
M
A
M
G
D
D
F
L
N
A
F
T
V
G
D
Q
L
L
W
--
G
A
A
E
P
L
R
R
T
L
R
I
I
L
A
E
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
37
Fugue
36.44
13%
213
- C3 -
1FE6
-
?
A:
[1-52]
----------------------
G
S
I
I
N
E
T
A
D
D
I
V
Y
R
L
T
V
I
I
D
D
R
Y
E
S
L
K
N
L
I
T
L
R
A
D
R
L
E
M
I
I
N
D
N
V
S
T
I
L
A
S
G
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
36.39
32%
-18
- C3 -
4R5M
1
DHAS1_VIBCH
A:
[217-282]
----------------------------------------------------------------------------------------------------------------------------------------------------
F
G
V
P
L
A
G
S
L
I
P
W
I
D
V
K
R
D
N
G
Q
S
K
E
E
W
K
A
G
V
E
A
N
K
I
--------
L
G
L
Q
D
S
P
V
-
P
I
D
---
G
T
C
---
V
R
I
G
A
M
R
C
H
S
Q
A
L
T
I
K
L
K
Q
N
I
P
L
D
E
I
E
--
E
M
--
I
A
--
T
H
N
D
W
V
-
K
V
I
P
N
E
R
D
I
T
A
R
E
L
T
P
A
K
V
T
G
T
L
S
V
P
V
G
R
L
R
K
M
A
M
G
D
D
F
L
N
A
F
T
V
G
D
Q
L
L
W
--
G
A
A
E
P
L
R
R
T
L
R
I
I
L
A
E
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
36
Fugue
33.55
19%
292
- C3 -
2Z5I
-
?
I:
[5-40]
----------------------------------------
M
D
A
I
K
K
K
M
Q
M
L
K
L
D
K
E
N
A
L
D
R
A
E
Q
L
E
N
E
V
A
R
L
K
K
L
V
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------