@TOME V2.2
(Nov 2016)
Ref.
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : ZNT6_HUMAN: (2015-12-12 )
MGTIHLFRKPQRSFFGKLLREFRLVAADRRSWKILLFGVINLICTGFLLMWCSSTNSIALTAYTYLTIFDLFSLMTCLISYWVTLRKPSPVYSFGFERLEVLAVFASTVLAQLGALFILKESAERFLEQPEIHTGRLLVGTFVALCFNLFTMLSIRNKPFAYVSEAASTSWLQEHVADLSRSLCGIIPGLSSIFLPRMNPFVLIDLAGAFALCITYMLIEINNYFAVDTASAIAIALMTFGTMYPMSVYSGKVLLQTTPPHVIGQLDKLIREVSTLDGVLEVRNEHFWTLGFGSLAGSVHVRIRRDANEQMVLAHVTNRLYTLVSTLTVQIFKDDWIRPALLSGPVAANVLNFSDHHVIPMPLLKGTDDLNPVTSTPAKPSSPPPEFSFNTPGKNVNPVILLNTQTRPYGFGLNHGHTPYSSMLNQGLGVPGIGATQGLRTGFTNIPSRYGTNNRIGQPRP
Atome Classification :
(20 SA)
.........10........20........----30..-------------......40........50.......------------.60....-----------------------....70......-------------..80........90......-------..100....-------...----110.----......120......-.-130.-.-....-.140.......----150......--------------.160.--......170.......180.....--..-------190.......200.......210.....-------..220.---...--------.----..230.-......240.......250...-....260.......270..---.-.--...280.-....---..290........300.....---..310..---.....320---.....----..330.......340..------------.....350.......360.......370-----.......380.......390.......400------.......410..-----------.....420.......430----.........440...------....450.--......460-----------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MG
T
I
H
L
FRK
P
Q
R
S
F
F
G
K
L
L
R
E
F
R
L
V
AADR----R
S
W
K
-------------
I
L
L
F
G
V
I
N
L
I
C
T
G
F
L
L
M
WCSSTN
S
I
------------
A
L
T
A
Y
T
Y
-----------------------
L
T
I
F
D
L
F
S
L
M
T
C
-------------
L
I
S
Y
W
V
TLRKPS
P
V
Y
S
F
G
F
E
-------
R
L
E
V
L
A
V
F
A
-------
S
T
V
----
L
A
Q
L
----
G
A
L
F
I
L
K
E
S
A
E
R
F
L
E-Q-PEIH-T-
G
R
L
L
-
V
G
T
F
V
A
L
C
F
N
L
----
F
T
M
L
SIRNK--------------
P
F
A
Y
V
--
S
EAA
S
T
S
W
L
Q
E
H
V
A
D
L
S
R
S
L
C
G
I
I--P
G
-------
L
S
S
I
FLPRMN
P
F
V
L
I
DL
A
G
A
F
A
L
C
I
T
Y
M
-------
L
I
E
IN
N
---
Y
F
A--------V----D
T
A
S
A
I
-
A
I
A
L
M
T
FGTMY
P
M
SVYS
G
K
V
L
L
-QTT
P
P
H
V
I
G
Q
L
D
K
L
I
R
E
V
S
---
T
-
L
--
D
G
V
L
E
V
R-NE
H
F
---
W
T
L-GFGSLA
G
S
V
H
V
R
I
RRDA---NEQ
M
V
L
A
---
H
V
T
N
R
L
Y
T
---
L
V
S
T
L
----
T
V
Q
I
FKDDWI
R
P
A
LLSG------------P
V
A
A
N
V
LNFSDH
H
V
I
PMPLLKGTDDLNP-----VTSTPAKPSSPPPEFSFNTPGKNV
N
P
V
I
L
L
------NTQTRPYGFGLN-----------HGH
T
P
Y
S
S
M
L
NQGLGV------PGIGATQGLRTGFTN------I
P
S
RYGTN--NRIGQPRP------------------------------
30
Fugue
79.26
19%
-91
* C8 *
3VSM
1
OE66_NPVAC
A:
[27-659]
--
N
I
Q
E
L
Q
N
F
E
R
W
F
K
N
N
L
S
Y
S
F
S
Q
K
A
E
K
V
V
NPN
R
N
W
N
DNTVFDNLSPWTS
V
P
D
F
G
T
V
C
H
T
L
I
G
Y
C
V
R
Y
N
N
T
S
D
T
L
YQN
P
E
L
A
Y
N
L
I
N
G
L
R
I
I
C
S
K
LPDPPPHQQAPWGPVADWYHFT
I
T
M
P
E
V
F
M
N
I
T
I
V
L
N
ETQH
Y
D
E
A
A
S
L
T
R
Y
W
L
G
L
Y
L
P
T
A
V
N
S
M
G
W
H
R
T
A
G
N
S
M
R
M
G
V
P
Y
T
Y
S
-------
Q
M
L
R
GYS
L
A
Q
I
R
Q
E
Q
G
I
Q
E
I
L
N
T
I
A
F
P
Y
V
T
-
Q
G
N
G
L
H
-
V
-
D
S
I
Y
-
I
D
H
I
D
V
R
A
Y
G
Y
----
L
I
N
S
Y
F
T
F
A
--------------
Y
Y
T
Y
Y
FG
D
E
V
I
N
T
V
G
L
T
R
A
I
E
N
V
G
S
P
E
G
V
V
V
--
P
G
VMSRNGT
L
Y
S
N
V
I
G
N
F
I
T
Y
P
L
A
V
H
S
A
D
Y
S
K
V
L
T
K
L
S
KT
Y
Y
G
S
V
V
G
V
T
N
RLA
Y
Y
E
--------
S
----
D
P
T
N
N
I
-
Q
A
P
L
W
T
M
A
R
----
R
I
W
N
R
R
G
R
I
-
I
N
Y
N
A
N
T
V
S
F
E
S
G
I
I
L
Q
-----
S
-
L
--
N
G
I
M
R
I
P
-
S
G
T
T
---
S
T
Q
-
S
F
R
P
T
I
G
Q
T
A
I
A
K
T
D
T
A
---
G
A
I
L
V
Y
A
K
F
A
E
M
N
N
L
Q
F
K
---
S
C
T
L
F
Y
DH
G
M
F
Q
L
Y
Y
N
I
G
V
E
P
N
S
L
N
N
T
N
G
R
V
I
VLSRDT
S
V
N
T
N
D
L
S
F
E
A
Q
R
I
N
N
N
N
S
S
E
G
T
T
F
N
G
V
-----
V
C
H
R
V
P
I
T
N
I
N
V
P
S
L
T
V
R
S
P
N
S
S
V
E
L
V
E
Q
I
I
S
F
Q
T
M
Y
T
A
T
A
S
A
C
Y
K
L
N
VEGHSDS
L
R
A
F
R
V
N
S
D
E
N
I
Y
V
N
V
G
N
G
V
K
A
L
F
N
Y
P
W
V
M
V
K
E
N
N
K
V
S
F
M
S
ANEDTT
I
P
F
S
V
I
M
N
S
F
T
S
I
G
E
P
A
L
Q
Y
S
P
SNCFVYGN
G
F
K
L
NNSTF
D
L
Q
F
I
F
E
I
V
17
HHSearch
63.03
17%
-112
* C9 *
3H90
-
FIEF_ECOLI
A:
[2-282]
---------------------------------
V
S
R
A
-------------
A
I
A
A
T
A
M
A
S
L
L
L
L
I
K
I
F
A
W
W
Y
T
G
S
V
------------
S
I
L
A
A
L
V
-----------------------
D
S
L
V
D
I
G
A
S
L
T
N
-------------
L
L
V
V
R
Y
S
L
Q
P
A
D
D
N
H
S
F
G
H
G
-------
K
A
E
S
L
A
A
L
A
-------
Q
S
M
----
F
I
S
G
----
S
A
L
F
L
F
L
T
G
I
Q
H
L
I
S
-
P
-
T
P
M
T
D
P
-
G
V
G
V
-
I
V
T
I
V
A
L
I
C
T
I
----
I
L
V
S
F
Q
R
W
V
--------------
V
R
R
T
Q
--
S
Q
-------------------------
A
-------
V
R
A
D
M
L
-----
H
Y
Q
S
D
V
M
M
N
G
A
I
L
L
A
L
G
-------
L
S
W
-
Y
G
---
W
H
R
--------
A
----
D
A
L
F
A
L
-
G
I
G
I
Y
I
L
Y
S
A
L
R
M
G
Y
E
A
V
Q
S
L
L
-
D
R
A
L
P
D
E
--
E
R
Q
E
I
I
D
I
V
T
---
S
-
W
--
P
G
V
S
G
A
H
-
D
L
R
T
---
R
Q
S
-
G
P
-
T
R
F
I
Q
I
H
L
E
M
E
D
S
L
P
L
V
Q
A
H
M
V
A
D
---
Q
V
E
Q
A
I
L
R
R
F
-
P
G
S
D
V
----
I
I
H
Q
D
P
C
S
V
V
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
33
Fugue
60.89
19%
-79
- C5 -
3THI
-
THI1_PANTH
A:
[1-362]
-
I
T
L
K
V
A
I
Y
P
------
Y
V
P
D
P
A
R
F
Q
A
A
V
L
----
D
Q
W
Q
-------------
R
Q
E
P
G
V
-
K
L
E
F
T
D
----
W
D
S
Y
S
A
D
P
------------
P
D
D
------------------------------
L
D
V
F
V
L
D
S
I
-------------
F
L
S
H
F
V
D
---
A
G
Y
L
L
P
F
G
S
Q
-------
D
I
D
----------------------------
Q
A
E
D
V
L
P
F
A
L
Q
G
A
K
R
-
N
-
G
E
V
Y
---------
G
L
P
Q
I
L
C
T
N
L
----
L
F
Y
R
K
G
D
-----------------------
L
K
I
G
Q
V
D
N
I
Y
E
L
Y
K
K
I
G
T
S
H
S
E
Q
I
--
P
--------------
P
P
Q
N
K
G
L
L
I
N
M
A
G
G
T
T
K
A
S
M
Y
L
-------
E
A
L
I
D
V
T
GQ
Y
T
E
--------
Y
----
D
L
L
P
P
L
D
P
L
N
D
K
V
I
R
G
L
R
L
L
I
N
M
A
G
E
K
P
S
-
Q
Y
V
P
E
D
--
G
D
A
Y
V
R
A
S
W
F
A
---
Q
-
G
--
S
G
R
A
F
I
G
Y
S
E
S
M
---
M
R
M
-
G
--
D
Y
A
E
Q
V
R
F
K
P
I
S
S
S
---
A
G
Q
D
I
P
L
---
F
Y
S
D
V
V
S
V
---
N
S
K
T
A
----
H
P
E
L
A
K
K
--
L
A
N
V
M
A
S
A
------------
D
T
V
E
Q
A
L
R
P
Q
A
D
G
Q
Y
P
Q
Y
L
L
P
A
R
H
Q
V
Y
E
-----
A
L
M
Q
D
-
Y
P
I
Y
S
E
L
A
Q
I
V
N
K
P
S
---
N
R
V
F
R
L
------
G
P
E
V
R
T
W
L
K
D
A
K
-----------
Q
-------
V
L
P
E
A
L
G
----------------------------------------------------------------------------
29
Fugue
55.73
13%
-87
- C9 -
2QFI
-
FIEF_ECOLI
A:
[5-290]
-------------------------
Y
G
R
L
----
V
S
R
A
-------------
A
I
A
A
T
A
M
A
S
L
L
L
L
I
K
I
F
A
W
W
Y
T
G
S
V
------------
S
I
L
A
A
L
V
-----------------------
D
S
L
V
D
I
G
A
S
L
T
N
-------------
L
L
V
V
R
Y
S
L
Q
P
A
D
D
N
H
S
F
G
H
G
-------
K
A
E
S
L
A
A
L
A
-------
Q
S
M
----
F
I
S
G
----
S
A
L
F
L
F
L
T
G
I
Q
H
L
I
S
-
P
-
T
P
M
T
-
D
-
P
G
V
G
-
V
I
V
T
I
V
A
L
I
C
T
----
I
I
L
V
----
S
--------------
F
Q
R
W
V
--
V
R
R
T
Q
S
Q
A
V
R
A
D
M
L
H
Y
Q
S
D
V
M
M
N
G
--
A
I
-------
L
L
A
L
G
L
S
W
-------------------------------
Y
G
---
W
H
R
--------
A
----
D
A
L
F
A
L
-
G
I
G
I
Y
I
L
Y
S
A
L
R
M
G
Y
E
A
V
Q
S
L
L
D
R
A
L
P
D
E
E
R
Q
E
I
I
D
I
V
T
S
W
P
---
G
-
V
--
S
G
A
H
D
L
R
-
T
R
Q
S
---
G
P
T
-
R
F
I
Q
I
H
L
E
M
E
D
S
L
P
L
-
V
---
Q
A
H
M
V
A
D
---
Q
V
E
Q
A
I
L
R
---
R
F
P
G
S
----
D
V
I
I
H
Q
D
P
C
S
V
V
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
32
Fugue
55.34
12%
-93
* C7 *
3AU7
1
TIAS_ARCFU
A:
[20-402]
------
H
M
R
V
W
V
G
I
D
T
Y
L
A
V
L
A
M
E
R
V
E
R
E
----
L
G
K
V
-------------
I
G
F
P
R
L
I
R
L
---------
N
P
T
I
N
G
A
------------
V
S
F
L
V
E
V
-----------------------
D
D
V
G
E
L
V
D
V
V
N
E
-------------
V
I
I
------
E
P
G
A
V
F
V
D
E
E
L
-------
A
V
K
L
K
P
F
A
D
-------
K
A
I
----
K
D
V
L
----
Q
I
D
E
A
L
F
V
I
G
K
Y
F
I
P
-
H
-
L
R
H
K
-
K
-
G
R
G
L
-
I
G
A
L
A
A
V
G
A
E
L
E
D
F
T
L
E
L
I
A
Y
R
Y
P
--------------
E
R
F
G
T
--
E
R
E
Y
D
E
E
S
F
F
D
M
D
Y
E
L
Y
P
Q
T
F
D
N
V
DW
C
N
-------
D
V
V
V
C
I
P
N
T
P
C
P
V
L
Y
G
I
R
G
E
S
----
V
E
A
-------
L
Y
K
A
M
E
---
S
V
K
--------
T
----
E
P
V
D
R
R
-
M
I
F
V
T
N
H
A
T
D
M
H
L
I
G
E
E
E
V
H
R
L
-
E
--
N
Y
R
S
Y
R
L
R
G
R
V
T
L
E
P
Y
---
D
-
I
--
E
G
-----------------------
G
H
V
F
F
E
I
D
T
K
F
---
G
S
V
K
C
A
A
F
--
E
P
T
K
Q
F
R
N
---
V
I
R
L
L
----
R
----
K
G
D
---
V
V
E
V
Y
G
------------
S
M
K
K
D
T
I
N
L
E
K
I
Q
I
V
E
L
A
E
G
S
E
R
E
L
Q
P
G
-----
F
Y
E
V
P
P
S
A
R
--------------------------------------
R
-----------
H
L
S
K
P
L
I
R
M
N
V
E
G
R
H
I
------
F
R
-------------------------------------------------------------------
18
HHSearch
52.23
14%
-112
- C9 -
3J1Z
-
?
P:
[9-292]
---------------------------
F
W
----
V
K
L
A
-------------
S
R
A
S
V
A
T
A
L
T
L
I
T
I
K
L
L
A
W
L
Y
S
G
S
A
------------
S
M
L
A
S
L
T
-----------------------
D
S
F
A
D
T
L
A
S
I
I
N
-------------
F
I
A
I
R
Y
A
I
V
P
A
D
H
D
H
R
Y
G
H
G
-------
K
A
E
P
L
A
A
L
A
-------
Q
S
A
----
F
I
M
G
----
S
A
F
L
L
L
F
Y
G
G
E
R
L
L
N
-
P
-
S
P
V
E
-
N
A
T
L
G
V
-
V
V
S
V
V
A
I
V
L
T
L
----
A
L
V
L
L
Q
K
R
A
--------------
L
A
A
T
N
--
S
T
-------------------------
V
-------
V
E
A
D
S
L
-----
H
Y
K
S
D
L
F
L
N
A
A
V
L
L
A
L
V
-------
L
S
Q
-
Y
G
---
W
W
W
--------
A
----
D
G
L
F
A
V
-
L
I
A
C
Y
I
G
Q
Q
A
F
D
L
G
Y
R
S
I
Q
A
L
L
-
D
R
E
L
D
E
D
--
T
R
Q
R
I
K
L
I
A
K
---
E
-
D
--
P
R
V
L
G
L
H
-
D
L
R
T
---
R
Q
A
-
G
K
-
T
V
F
I
Q
F
H
L
E
L
D
G
N
L
SLN
E
A
H
S
I
T
D
---
T
T
G
L
R
V
K
A
AF-
E
D
A
E
V
----
I
I
H
Q
D
P
V
Q
V
E
P
T
T
Q
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
35
Fugue
44.05
14%
-54
- C6 -
1W5C
-
PSBD_THEEB
D:
[1-350]
-
M
T
I
A
I
G
R
A
P
A
E
R
G
W
F
D
I
L
D
D
W
L
K
R
D
-------------------------------
R
F
V
F
V
G
W
S
G
I
L
L
F
P
C
A
Y
L
------------
A
L
G
G
W
L
T
-----------------------
G
T
T
F
V
---------------------
T
S
W
Y
T
H
G
L
A
S
S
Y
L
E
G
C
N
F
L
-------
T
V
A
V
------------
S
T
P
----
A
N
S
M
----
G
H
S
L
L
L
L
W
G
P
E
A
Q
G
D
-
F
-
T
R
W
C
-
Q
-
L
G
----
G
L
W
T
F
I
A
L
H
G
----
A
F
G
L
I
G
F
M
L
--------------
R
Q
F
E
I
--
A
R
L
V
G
--------------------------------------
V
R
P
Y
N
A
I
A
F
S
A
P
I
A
V
F
V
S
V
F
-------
L
I
Y
P
L
G
---
Q
S
S
--------
W
----
F
F
A
P
S
F
-
G
V
A
----
A
I
F
R
F
L
L
F
F
Q
G
F
H
N
W
-
T
L
N
P
F
H
M
M
G
V
A
G
V
L
G
G
A
L
L
---
C
-
A
--
I
H
G
A
T
V
E
-
N
T
L
F
---
Q
D
G
-
E
G
A
S
T
F
R
A
F
N
P
T
Q
A
E
E
T
---
Y
S
M
V
T
A
N
---
R
F
W
S
Q
I
F
G
---
I
A
F
S
----------
N
K
R
W
L
H
F
F
M
L
F
V
------------
P
V
T
G
--
L
W
M
S
A
I
G
V
V
G
L
A
L
N
L
R
S
Y
D
F
I
S
-----
Q
E
I
R
A
A
E
D
P
E
F
E
T
F
Y
T
K
N
L
L
L
N
E
G
I
R
A
W
M
A
------
P
Q
D
Q
P
H
E
N
F
V
F
P
-----------
E
E
V
L
P
R
G
N
-----------------------------------------------------------------------------------
36
Fugue
42.63
15%
-93
- C7 -
4D10
-
CSN7A_HUMAN
G:
[12-219]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
G
Q
N
Q
E
--------------
Q
F
L
L
L
--
A
K
S
A
K
G
A
A
L
A
T
L
I
H
Q
V
L
E
A
P
-
G
V
Y
--
V
F
-------
G
E
L
L
D
M
P
N
V
R
E
L
A
E
S
D
F
A
S
T
F
R
L
L
T
V
F
A
-------
Y
G
T
Y
A
D
---
Y
L
A
E
ARNLPPL
T
----
E
A
Q
K
N
K
-
L
R
H
L
S
V
V
T
L
A
A
K
V
K
C
I
P
Y
A
V
L
L
-
E
A
L
A
L
R
N
V
R
Q
L
E
D
L
V
I
E
A
V
Y
A
D
V
-
L
--
R
G
S
L
D
Q
R
-
N
Q
R
L
E
V
D
Y
S
I
-
G
R
D
I
Q
R
Q
D
L
S
A
I
A
R
T
L
Q
---
E
W
C
V
G
C
E
---
V
V
L
S
G
I
E
E
---
Q
V
S
R
A
----
N
Q
H
K
E
Q
Q
L
G
L
K
Q
Q
I
E
S
E
------------
V
A
N
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
31
Fugue
41.85
9%
-120
- C8 -
3EA0
2
?
A:
[3-242]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
K
R
V
F
G
F
V
S
AKGGDG
G
S
C
I
----
A
A
N
F
----
A
F
A
L
S
Q
E
P
D
I
H
V
L
A
V
-
D
-
I
S
L
P
-
F
-
G
D
L
D
M
Y
L
S
G
N
T
H
S
Q
D
L
----
A
D
I
S
N
A
S
D
R
LD
K
S
L
L
D
T
M
VQHIS
P
S
L
D
L
--
I
P
S
P
A
T
F
E
K
I
V
N
I
E
--
P
E
R
V
S
D
L
I
--
H
I
-------
A
A
S
F
Y
-----
D
Y
I
I
V
D
F
G
A
S
I
D
H
V
G
V
W
V
-------
L
E
H
L
D
E
---
L
C
I
--------
V
T
T
PS
L
Q
S
L
R
R
-
A
G
Q
L
L
K
L
C
K
E
F
E
K
P
I
S
R
I
E
I
I
L
-
N
R
A
D
T
N
S
R
I
T
S
D
E
I
E
K
V
I
G
---
R
P
I
--
S
K
R
I
P
Q
D
-
E
D
-------
A
M
Q
E
S
L
L
S
G
Q
S
V
L
K
V
A
P
K
S
---
Q
L
S
K
T
I
V
---
D
W
A
L
H
L
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
HHSearch
36.63
10%
-101
- C9 -
3W61
-
?
A:
[8-82]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
N
R
I
V
E
A
A
E
---
R
-
V
--
P
G
V
R
G
V
I
-
H
L
R
A
---
R
Y
V
-
G
Q
-
D
I
W
A
D
M
I
I
G
V
D
P
E
N
T
V
E
Q
A
H
E
I
C
E
---
A
V
Q
A
A
V
C
G
KIR
R
I
E
S
L
----
A
V
S
A
E
A
R
E
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
HHSearch
36.59
14%
-61
- C9 -
3BYP
-
?
A:
[6-87]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
L
P
P
E
E
--
V
E
R
I
R
A
F
L
Q
---
E
-
R
I
R
G
R
A
L
E
V
H
-
D
L
K
T
---
R
R
A
-
G
P
R
-
S
F
L
E
F
H
L
V
V
R
G
D
T
P
V
E
E
A
H
R
L
C
D
---
E
L
E
R
A
L
A
Q
A
F
-
P
G
L
Q
A
----
T
I
H
V
E
P
E
G
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
HHSearch
34.07
6%
-79
- C9 -
2ZZT
-
?
A:
[12-87]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
D
D
I
F
A
V
L
E
---
R
-
F
--
P
N
V
H
N
P
H
-
R
V
R
I
---
R
R
V
-
G
T
--
Y
F
I
E
M
D
I
E
V
D
G
K
M
S
V
K
D
A
H
E
L
T
V
---
K
I
R
K
E
M
L
K
R
R
D
D
I
E
D
V
----
T
I
H
V
E
P
L
G
N
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
31.50
25%
-48
- C9 -
3H90
-
FIEF_ECOLI
A:
[27-118]
-----------------------------------------------------------------------
T
G
S
V
------------
S
I
L
A
A
L
V
-----------------------
D
S
L
V
D
I
G
A
S
L
T
N
-------------
L
L
V
V
R
Y
S
L
Q
P
A
D
D
N
H
S
F
G
H
G
-------
K
A
E
S
L
A
A
L
A
-------
Q
S
M
----
F
I
S
G
----
S
A
L
F
L
F
L
T
G
I
Q
H
L
I
S
P
T
-
P
M
T
D
-
P
-
G
V
G
V
-
I
V
T
I
V
A
L
I
C
T
I
----
I
L
V
S
F
Q
R
W
V
--------------
V
R
R
T
Q
--
S
Q
A
V
R
A
D
M
L
H
Y
Q
S
D
V
M
M
N
G
A
I
L
L
A
--
L
G
-------
L
S
W
Y
G
W
H
R
A
D
A
L
F
A
L
G
I
G
I
Y
I
L
Y
S
A
L
R
M
-------
G
Y
E
A
V
Q
---
S
L
L
--------
D
----
R
A
L
P
D
E
-
E
R
Q
E
I
I
D
I
V
T
S
W
P
G
V
S
G
A
H
D
L
R
-
T
R
Q
S
G
P
T
R
F
I
Q
I
H
L
E
M
E
D
S
---
L
-
P
--
L
V
Q
A
H
M
V
-
A
D
Q
V
---
E
Q
A
-
I
L
R
R
F
P
G
S
D
V
I
I
H
Q
D
P
C
---
S
V
V
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
PsiBlast_CBE
31.25
37%
119
- C10 -
3NG9
3
?
E:
[610-663]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
D
V
Y
L
Q
G
------------
P
I
W
A
K
I
P
H
-
T
D
G
H
F
H
P
S
P
L
M
G
G
F
G
L
K
N
P
PPQIL
I
K
N
T
P
V
-
P
A
N
P
P
A
E
F
S
--------------------------------------------------------------------------------------------------------------------------------------
14
PsiBlast_CBE
31.17
37%
119
- C10 -
3NG9
3
?
D:
[610-663]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
D
V
Y
L
Q
G
------------
P
I
W
A
K
I
P
H
-
T
D
G
H
F
H
P
S
P
L
M
G
G
F
G
L
K
N
P
PPQIL
I
K
N
T
P
V
-
P
A
N
P
P
A
E
F
S
--------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_CBE
31.17
37%
119
- C10 -
3NG9
3
?
H:
[610-663]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
D
V
Y
L
Q
G
------------
P
I
W
A
K
I
P
H
-
T
D
G
H
F
H
P
S
P
L
M
G
G
F
G
L
K
N
P
PPQIL
I
K
N
T
P
V
-
P
A
N
P
P
A
E
F
S
--------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_CBE
31.15
37%
119
- C10 -
3NG9
4
?
J:
[610-663]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
D
V
Y
L
Q
G
------------
P
I
W
A
K
I
P
H
-
T
D
G
H
F
H
P
S
P
L
M
G
G
F
G
L
K
N
P
PPQIL
I
K
N
T
P
V
-
P
A
N
P
P
A
E
F
S
--------------------------------------------------------------------------------------------------------------------------------------
15
PsiBlast_CBE
31.11
37%
119
- C10 -
3NG9
3
?
C:
[610-663]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
D
V
Y
L
Q
G
------------
P
I
W
A
K
I
P
H
-
T
D
G
H
F
H
P
S
P
L
M
G
G
F
G
L
K
N
P
PPQIL
I
K
N
T
P
V
-
P
A
N
P
P
A
E
F
S
--------------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_CBE
31.10
37%
119
- C10 -
3NG9
3
?
G:
[610-663]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
D
V
Y
L
Q
G
------------
P
I
W
A
K
I
P
H
-
T
D
G
H
F
H
P
S
P
L
M
G
G
F
G
L
K
N
P
PPQIL
I
K
N
T
P
V
-
P
A
N
P
P
A
E
F
S
--------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
31.10
37%
119
- C10 -
3NG9
3
?
A:
[610-663]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
D
V
Y
L
Q
G
------------
P
I
W
A
K
I
P
H
-
T
D
G
H
F
H
P
S
P
L
M
G
G
F
G
L
K
N
P
P
P
Q
I
L
I
K
N
T
P
V
-
P
A
N
P
P
A
E
F
S
--------------------------------------------------------------------------------------------------------------------------------------