Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MADQPKPISPLKNLLAGGFGGVCLVFVGHPLDTVKVRLQTQPPSLPGQPPM---YSGTFDCFRKTLFREGITGLYRGMAAPIIGVTPMFAVCF---------FGFGLGKKLQQKHPEDVLSYPQLFA--------AGMLSGVFTTGIMTPGERIKCLLQIQASSGESKYTGTLDCAKKLYQEFGIRGIYKGTVLTLMRDVPASGMYFMTYEWLKNIFTPEGKRVSELSAPRILVAGGIAGIFNWAVAIPPDVLKSRFQ--TAPPGKYPNGFRDVLRELIRDEGVTSLYKGFNAVMIRAFPANAACFLGFEVAMKFLNWATPNL 4C9H Chain:A ((24-294)) ----------LIDFLMGGVSAAVAKTAASPIERVKLLIQNQDEMLK-QGTLDRKYAGILDCFKRTATQEGVISFWRGNTANVIRYFPTQALNFAFKDKIKAMFGF--------KKEE---GYAKWFAGNLASGGAAGALSLLFVYSLDYARTRLAADS-------ARQFNGLIDVYKKTLKSDGVAGLYRGFLPSVVGIVVYRGLYFGMYDSLK---------LASFLLGWVVTTGAS------TCSYPLDTVRRRMMMTSGQAVKYDGAF-DCLRKIVAAEGVGSLFKGCGANILRGVAGAGVISMYDQLQMILFGKKFK--

General information: TITO was launched using: RESULT: Template: 4C9H.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -62665 for 1645 contacts (-38.1/contact) + 2D Compatibility (PS) -23255 + (NN) 5191 + (LL) 2096 1D Compatibility (HY) -17600 + (ID) 3700 Total energy: -99933.0 ( -60.75 by residue) QMean score : 0.094

(partial model without unconserved sides chains): PDB file : Tito_4C9H.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4C9H-query.scw PDB file : Tito_Scwrl_4C9H.pdb: