Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MDHSHHMGMSYMDSNSTMQPSHHHPTTSASHSHGGGDSSMMMMPMTFYFGFKNVELLFSGLVINTAGEMA-GAFVAVFLLA------MFYEGLKIARESLLRKSQVSIRYNSMPVPGPN-GTILMETHKTVGQQMLSFPHLLQTVLHIIQVV--ISYFLMLIFMTYNG-YLCIAVAAGAGTGYFLFSWKKAVVVDITEHCH 1VR8 Chain:A ((5-141)) KIHHHH----------------HHPPEAYS-----LDTAIFVLETRDYRLSDVKEI-------DSYGDVEMKGKVAVFETEYGPVFLYVYKGEEAKKIWKKLNGRVSIRSVL---DLPNMGKFSTVSN---GKKIVAWWR--KNWLFIVEGKNGVEEFVKHVYRVYEEMKQ------------------------------

General information: TITO was launched using: RESULT: Template: 1VR8.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -74851 for 828 contacts (-90.4/contact) + 2D Compatibility (PS) -13396 + (NN) -2568 + (LL) 4508 1D Compatibility (HY) -2400 + (ID) 1450 Total energy: -90157.0 ( -108.89 by residue) QMean score : 0.124

(partial model without unconserved sides chains): PDB file : Tito_1VR8.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1VR8-query.scw PDB file : Tito_Scwrl_1VR8.pdb: