Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MASWSHPQFEKGADDDDKS-----------EPPVSMLMQVAGAVETSKGGEKWAPVTRNK---------FLFVGTQVRTGADG--------GGKLIDQNSGMAQTIGAN---------SVVEITAAGPKAVSGSLSAPEAASGDL-----------VAGLSNRFAEAQ-------RYTTVRRSVKKEAADLKLRVASDITLSPTYPDLV-WENMGAQYGYTLVIDGTSHA------VPATSGEMVRFRVPSLTPGA----HSFGVTVTEGGQAVGQTEKGGTIVWLSATEDKALVDGVARVKAASTGDEFALGNYLDSKG------VTVAAMDAYRKHFASHKDDNDMRP--------------LLIKTYNDLKLRDLRQ--KEALVYNEQLEGN--PG-------------------FSSISAHHHHHHHHHH-- 3CM8 Chain:A ((12-471)) IEPFLKTTPRPLRLPDGPPCSQRSKFLLMDALKLSIEIPLYDAIKCMKTFFGWKEPNIVKPHEKGINPNYLLAWKQVLAELQDIENEEKIPKTKNMRKTSQLKWALGENMAPEKVDFEDCKDVSEPKPRSLASWIQSEFNKACELTDSSWIELDEIIASMRRNYFTAEVSHCRATEYIMKGVYINTALLNASCAAMDDFQLIPMISKCRTKEGRRKTNLYGFIIKGRSHLRNDTDVVNFVSMEFS-LTDPRLEPHKWEKYCVLEIGDMLLRTAIGQVSRPMFLYVRTNGTSKIKMKWGMEMRRCLLQSLQQIESMIEAESSVKEKDMTKEFFENKSETWPIGESPKGMEEGSIGKVCRTLLAKSVFNSLYASPQLEGFSAESRKLLLIVQALRDNLEPGTFDLGGLYEAIEECLINDPWVLLNASWFNSFLTHALK

General information: TITO was launched using: RESULT: Template: 3CM8.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) 20706 for 2113 contacts (9.8/contact) + 2D Compatibility (PS) -33469 + (NN) -7296 + (LL) 100 1D Compatibility (HY) -16000 + (ID) 2400 Total energy: -38359.0 ( -18.15 by residue) QMean score : 0.172

(partial model without unconserved sides chains): PDB file : Tito_3CM8.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3CM8-query.scw PDB file : Tito_Scwrl_3CM8.pdb: