Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MVGYDPKPDGRNNTKFQVAVA---------GSVSGLVTRALISPFDVIK-----IRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAFWKGHVPAQILSIGYGAVQFLSFEMLTELVHRGSVYDAREFSVHFVCGGLAACMATLTVHPVDVLRTRFAAQGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQFSCYSSLKHLYKWAIPAEGKKNENLQNLLCGSGAGVISKTLTYPLDLFKKRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTGFMFFSYEFFCNVFHCMNRTASQR 4QYX Chain:A ((2-236)) -----------APKKVLLALTSYNDVFYSDGAKTGVFVVEALHPFNTFRKEGFEVDFVSETGKFGWDEHSLAKDFLNGQDETDFKNKDS-----------------------DFNKTLAKIKTPKEVNADDYQIFFASAGHGTLFDYPKAKDLQDIASEIYANG--GVVAAVCHGPAIFDGLTDKKTGRPLIEGKSITGFTDVGETIL---------GVDSILKAKNLATVEDVAKKYGA-----KYLAPVGPWDDYSITDG-------------------------------RLVTGVNPASAHSTAVRSIVALK------------------

General information: TITO was launched using: RESULT: Template: 4QYX.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -132535 for 2014 contacts (-65.8/contact) + 2D Compatibility (PS) -23550 + (NN) -5045 + (LL) 6792 1D Compatibility (HY) -2800 + (ID) 1300 Total energy: -158438.0 ( -78.67 by residue) QMean score : 0.274

(partial model without unconserved sides chains): PDB file : Tito_4QYX.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4QYX-query.scw PDB file : Tito_Scwrl_4QYX.pdb: