Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MADKQISLPAKLINGGIA-GLIGVTCVFPIDLAKTRLQNQQNGQRVYTSMSDCLIKTVRSEGYFGMYRGAAVNLTLVTPEKAIKLAANDFFRHQLSKDGQKLTLLKEMLAGCGAGTCQVIVTTPMEMLKIQLQDAGRIAAQRKILAAQGQLSAQGGAQPSVEAPAAPRPTATQLTRDLLRSRGIAGLYKGLGATLLRDVPFSVVYFPLFANLNQLGRPASEEKSPFYVSFLAGCVAGSAAAVAVNPCDVVKTRLQ--SLQRGVNEDTYSGILDCARKILRHEGPSAFLKGAYCRALVIAPLFGIAQVVYFLGIAESLLGLLQDPQA---- 1FWK Chain:A ((1-296)) -MKVRVKAPCTSANLGVGFDVFGLCLKEPYDVIEVEAIDDKE-------------IIIEVDDK---------NIPTDPDKNVAGIVAKKMIDDFNIGKGVKITIKKGVKAGSGLGSSAASSAGTAYAIN-ELFKLNLDKLKLVDYASYGELASSGAKHADNVAPAIFGGFTMVTNYEPLEVLHI---------PIDFKLDILIAIPNISINTKEAREILPKAVGLKDLVNNVGKACGMVYALYNKDKSLFGRYMMSDKVIEPVRGKLIPNYFKIKEE-VKDKVYGITISGSGPSIIAFPKEEFIDEVENILRDYYENTIRTEVGKGVEVV

General information: TITO was launched using: RESULT: Template: 1FWK.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -56366 for 2591 contacts (-21.8/contact) + 2D Compatibility (PS) -30607 + (NN) -6160 + (LL) 2460 1D Compatibility (HY) 2000 + (ID) 1750 Total energy: -90423.0 ( -34.90 by residue) QMean score : 0.157

(partial model without unconserved sides chains): PDB file : Tito_1FWK.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1FWK-query.scw PDB file : Tito_Scwrl_1FWK.pdb: