Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MASVLSY-------------ESLVHAVAGAV------GSVTAMTV--FFPLDTARL-----RLQVDEKRKSKTTHMVLLEIIKEEGLLAPYRGWFPVISSLCCSNFVYFYTFNSLK----------------ALWVKGQHSTT------GKDLVVGFVAGVVNVLLTTP------------LWVVNT----RLKLQGAKFRNEDI---VPTNYKGIIDAFHQIIRDEGISALWNGTFPSLLLVFNPAIQFMFYEGLKRQLLKKRMKLS-----SLDVFI---------IGAVAKAIATTVTYPLQTVQSILRFGRHRLNPE--NRTLGSLRNILYLLHQRVRR------------FGIMGLYKGLEAKLL---QTVLTAALMFLVYEKLTAATFTVMGLKRAHQH------------------------ 4XR7 Chain:B ((1-456)) MHSLLQYRSADQLFIPNNIREDLTKKNLSILQVFPSSGKVIPSIVQDYFNLVPLNFNNKTTLFKVFSNYDGKAYVLKRLPNIDKSMNPNKISKIYQIWSKINCTNLIKFRDIFQTTKFGDLSICLVFDYYPNSLSLYDYHFVNFPKFPITNNYLWIYLVQLTNVINSIHSQNLSIGNTLNWRKVLITGDPGRIKLSHCNFMDLLFNDDTDTVVSSTIEGQQQLDYKYLGELLFNLSINIENSNNNTAPKEYRLEEITPQSIDDMRQIDDKFKDVLKYLISDNGDSKKSIHDLTSHFYDKMFMVLESSQTYTEYMESVLSRELENGRLFRLVNKLNCIFGRIESRIDINWSESGTKFPIILFYDYVFHQVDSNGKPIMDLTHVLRCLNKLDAGIQEKLMLVTPDELNCIIISYKELKDLIESTFRSITQH

General information: TITO was launched using: RESULT: Template: 4XR7.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -112432 for 1699 contacts (-66.2/contact) + 2D Compatibility (PS) -30956 + (NN) 5608 + (LL) 0 1D Compatibility (HY) -19600 + (ID) 2900 Total energy: -160280.0 ( -94.34 by residue) QMean score : 0.128

(partial model without unconserved sides chains): PDB file : Tito_4XR7.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4XR7-query.scw PDB file : Tito_Scwrl_4XR7.pdb: