Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKNLLCLLALLLCTTVFAQPQQVVVGVSGNGYVTRQQDGARITQRGVTHWTNPKSIVSIYFY-LHQPTTADLSLYAK---GHSEIKVSYGKKGFKVNLQSND----FTKVPVGSIDIRQAGYVRIDLQGVSKSGEGFGEIKQLIADNVTGKSNYVKDFSDYWGRRGPSVHLGYALPEGDTEWFYNEITVPKEGETMHSYYMAAGFGEGYFGMQYNSPTERRILFSVWSPFDTQNPKEIPDDQKIKLLRQGKDVHIGEFGNEGSGGQSYLKYPWKAGNTYKFLMQIRPDGNGNTTYTAYFYATDEKEWKLIASFLRPKTNTWYKRPHSFLENFSPEQGYLSREVFFGNQWARSKEGKWSRLTDATFTHDATASAQVRLDYQGGNTKDNRFYLKMGGFFNESVPMGTKFYCKPTGKEPEIDWEALKQL 4KMQ Chain:A ((987-1083)) ----------------------------------------------VAGFDAEKEAVEFDIDAVDGASDYTMEVRYSAGVEDATRTVYINGKKQQITLPKTANWDTWNTVEV-PVTLQ-AGNNQVVFDFEADDTA-GINFDHVVIK----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 4KMQ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -57197 for 587 contacts (-97.4/contact) + 2D Compatibility (PS) -9361 + (NN) 1611 + (LL) 16092 1D Compatibility (HY) -4800 + (ID) 500 Total energy: -54155.0 ( -92.26 by residue) QMean score : 0.112

(partial model without unconserved sides chains): PDB file : Tito_4KMQ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4KMQ-query.scw PDB file : Tito_Scwrl_4KMQ.pdb: