Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSALNW--------------KPFVYGGLASITAECGT----------------FPIDLTKTRLQIQGQTNDAKFKEIRYRGML----HALVRIGREEGLKALYSGIAPAMLRQASYGTIKI-----GTYQSLKRLFIE---RPEDETLPINVIC-----------GILSGVISSTIANPTDVLKIRMQAQSNTIQGG----MIGNFMNIYQQEGTRGLWKGVSLTAQRAAIVVGVELPVYDI------TKKHL-----ILSGLMGDTVYTHFLSSFTCGLAGALASNPVDVVRTRMMNQRVLRDGRCSGYTG-----------TLDCLLQTWKNEGFFALYKGFWPNW------LRLGPWNI-------------------IFFVTYEQLKKLDL-------------------------------- 4QLA Chain:A ((19-442)) LDLEEWWGPPELKQKQDTSIKPFEITFSETMVKELKERIKKRRPFAPPLEGVGFKYGFNSKQLDSWLKYWAEEYPFAERQKFLNQYPHFKTNI---QGLNIHFMRITPKVPKGVEIVPLLLLHGWPGSVREFYEAIPHLTAVSKDRNFALEIIAPSLPGYGFSDAAVRPGLAAAEVAVIFKNLMARLGYKQYYVQGGDWGALIGSAMATFFPKEIIGFHSNMALTLSPAATFLEFVGALFPSLIVEPELANRLYPLSEKYSTLLEELGYMHIQATKPDTVGIGLTDSPAGLLAYILEKFSTWTNPDLRSKEDGGLSYRWTKDQLIDNLMLYWSTKSIVTSMRLYAESFSSRHFDLKLDEIQVQVPTWVLQAKHELAYQPPCILKMKYPKLVNASVIEDGGHFLAFELPEIFAKDVLKAIGEFRKLKN

General information: TITO was launched using: RESULT: Template: 4QLA.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -93398 for 1886 contacts (-49.5/contact) + 2D Compatibility (PS) -29166 + (NN) 3401 + (LL) 32 1D Compatibility (HY) -16400 + (ID) 2350 Total energy: -137881.0 ( -73.11 by residue) QMean score : 0.122

(partial model without unconserved sides chains): PDB file : Tito_4QLA.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4QLA-query.scw PDB file : Tito_Scwrl_4QLA.pdb: