Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MAVSSNGGAIKAVIYDCDGVMFDSFEANLAFYQRIMEMMGRPR-LSRDNEEQMRILHTYANREVLAHFFP------------------------SPGDWEEAVRCAGAIDYRELVPLMIMEEGFREALDTLKG-RVGLGVCTNRSTS-MDMVLRLFSLDSYFSIVMTASRVTNPKPHPEPLLKVLEHFGIGPREALFVGDSEVDRLSAEAAGVPFVAYKAP------L---PAAYRMEHHREIIDLLG 2HI0 Chain:A ((2-237)) -------MKYKAAIFDMDGTILDTSADLTSALNYAFEQTGHRHDFTV---EDIKNFFGSGVVVAVTRALAYEAGSSRESLVAFGTKDEQIPEAVTQTEVNRVLEVFKPYYADHCQIKTGPFPGILDLMKNLRQKGVKLAVVSNKPNEAVQVLVEELFP-GSFDFALGEKSGIRRKPAPDMTSECVKVLGVPRDKCVYIGDSEIDIQTARNSEMDEIAVNWGFRSVPFLQKHGATVIVDTAEKLEEAI-

General information: TITO was launched using: RESULT: Template: 2HI0.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -165289 for 1706 contacts (-96.9/contact) + 2D Compatibility (PS) -22045 + (NN) -14757 + (LL) -64 1D Compatibility (HY) -8000 + (ID) 1500 Total energy: -211655.0 ( -124.07 by residue) QMean score : 0.418

(partial model without unconserved sides chains): PDB file : Tito_2HI0.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2HI0-query.scw PDB file : Tito_Scwrl_2HI0.pdb: