Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence METVPPAVDLVLGASACC---------LACVFTNPLEVVKTRLQLQGELQARGTYPRPYHGFIASVAAVARADGLWGLQKGLAAGLLYQGLMNGVRFYCYSLACQAGLTQQPGGTVVAGAVAGALGAFVGSPAYLIKTQLQAQTVAAVAVGHQHNHQTVLGALETIWRQQGLLGLWQGVGGAVPRVMVGSAAQLATFASAKAWVQKQQWLPEDSWLVALAGGMISSIAVVVVMTPFDVVSTRLYNQPVDTAGRGQLYGGLTDCMVKIWRQEGPLALYKGLGPAYLRLGPHTILSMLFWDELRKLAGRAQHKGT 1DK4 Chain:A ((1-252)) MKWDEIGKNIAKEIEKEILPYFGRKDKSYVVGTSPSGDETEIFDKISEDIALKYLKSLNVNIVSEELGVIDNSSEWTVVIDPIDG--SFNFINGIPFFAFCFGVFKN-NEPYYGLTYEFLTKSFYEAYKGKGAYLNGRKIKVKD----------FNPNNIVISYYPSKKIDLEKLRNKVKR--VRIFGAFGLEMCYVAK---------------------GTLDAVFDVRPKVRAVDIASSYIICKEAG--------ALITDENGDELKFDLNATDRLNIIVANSKEMLDIILDLL-----------------

General information: TITO was launched using: RESULT: Template: 1DK4.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -148387 for 2156 contacts (-68.8/contact) + 2D Compatibility (PS) -24922 + (NN) 6092 + (LL) 5708 1D Compatibility (HY) -1600 + (ID) 1650 Total energy: -164759.0 ( -76.42 by residue) QMean score : 0.160

(partial model without unconserved sides chains): PDB file : Tito_1DK4.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1DK4-query.scw PDB file : Tito_Scwrl_1DK4.pdb: