Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MHREPAKKKAEKRLFDASSFGKDLLAGGVAAAVSKTAVAPIERVKLLLQVQASS-KQISPEARYKGMVDCLVRIPREQGFFSFWRGNLANVIRYFPTQALNFAFKDKYKQLFMSGVNKEKQFWRWFLANLASGGAAGATSLCVVYPLDFARTRLGVD-IGKGPEERQFKGLGDCIMKIAKSDGIAGLYQGFGVSVQGIIVYRASYFGAYDTVKGLLPKPKKTPFLVSFFIAQVVTTCSGILSYPFDTVRRRMMMQSGEAKRQYKGTLDCFVKIYQHEGISSFFRGAFSNVLRGTGGALVLVLYDKIKEFFHIDIGGR 4C9H Chain:A ((21-309)) -----------------SNFLIDFLMGGVSAAVAKTAASPIERVKLLIQNQDEMLKQGTLDRKYAGILDCFKRTATQEGVISFWRGNTANVIRYFPTQALNFAFKDKIKAMF--GFKKEEGYAKWFAGNLASGGAAGALSLLFVYSLDYARTRLAADS------ARQFNGLIDVYKKTLKSDGVAGLYRGFLPSVVGIVVYRGLYFGMYDSLK-----------LASFLLGWVVTTGASTCSYPLDTVRRRMMMTSGQAVK-YDGAFDCLRKIVAAEGVGSLFKGCGANILRGVAGAGVISMYDQLQMILFGKKFK-

General information: TITO was launched using: RESULT: Template: 4C9H.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -71412 for 2007 contacts (-35.6/contact) + 2D Compatibility (PS) -27210 + (NN) 2363 + (LL) 1868 1D Compatibility (HY) -27600 + (ID) 7850 Total energy: -129841.0 ( -64.69 by residue) QMean score : 0.201

(partial model without unconserved sides chains): PDB file : Tito_4C9H.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4C9H-query.scw PDB file : Tito_Scwrl_4C9H.pdb: