Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MADKQISLPAKLINGGIAGLIGVTCVFPIDLAKTRLQNQQNG------QRVYTSMSDCLIKTVRSEGYFGMYRGAAVNLTLVTPEKAIKLAANDFFRHQL---SKDGQKLTLLKEMLAGCGAGTCQVIVTTPMEMLKIQLQDAGRIAAQRKILAAQGQLSAQGGAQPSVEAPAAPRPTATQLTRDLLRSRGIAGLYKGLGATLLRDVPFSVVYFPLFANLNQLGRPASEEKSPFYVSFLAGCVAGSAAAVAVNPCDVVKTRLQSLQRGVNEDTYSGILDCARKILRHEGPSAFLKGAYCRALVIAPLFGIAQVVYFLGIAESLLGLLQDPQA 4C9G Chain:A ((27-287)) -----------FLMGGVSAAVAKTAASPIERVKLLIQNQDEMLKQGTLDRKYAGILDCFKRTATQEGVISFWRGNTANVIRYFPTQALNFAFKDKIKAMFGFKKEEGYAKWFAGNLASGGAAGALSLLFVYSLDY-------------ARTRLAADS--------RQFNGLIDVYKKT--------LKSDGVAGLYRGFLPSVVGIVVYRGLYFGMYDSL--------------LASFLLGWVVTTGASTCSYPLDTVRRRM--MMTSGQAVKYDGAFDCLRKIVAAEGVGSLFKGCGANILRGVAGAGVISMYDQLQ--------------

General information: TITO was launched using: RESULT: Template: 4C9G.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -43779 for 1667 contacts (-26.3/contact) + 2D Compatibility (PS) -24043 + (NN) 532 + (LL) 5204 1D Compatibility (HY) -14000 + (ID) 3250 Total energy: -79336.0 ( -47.59 by residue) QMean score : 0.122

(partial model without unconserved sides chains): PDB file : Tito_4C9G.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4C9G-query.scw PDB file : Tito_Scwrl_4C9G.pdb: