Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MADKQISLPAKLINGGIAGLIGVTCVFPIDLAKTRLQNQQNG------QRVYTSMSDCLIKTVRSEGYFGMYRGAAVNLTLVTPEKAIKLAANDFFRHQL---SKDGQKLTLLKEMLAGCGAGTCQVIVTTPMEMLKIQLQDAGRIAAQRKILAAQGQLSAQGGAQPSVEAPAAPRPTATQLTRDLLRSRGIAGLYKGLGATLLRDVPFSVVYFPLFANLNQLGRPASEEKSPFYVSFLAGCVAGSAAAVAVNPCDVVKTRLQSLQRGVNEDTYSGILDCARKILRHEGPSAFLKGAYCRALVIAPLFGIAQVVYFLGIAESLLGLLQDPQA 4C9H Chain:A ((27-287)) -----------FLMGGVSAAVAKTAASPIERVKLLIQNQDEMLKQGTLDRKYAGILDCFKRTATQEGVISFWRGNTANVIRYFPTQALNFAFKDKIKAMFGFKKEEGYAKWFAGNLASGGAAGALSLLFVYSLDY-------------ARTRLAADS-------ARQFNGLIDVYKKT--------LKSDGVAGLYRGFLPSVVGIVVYRGLYFGMYDSLK-------------LASFLLGWVVTTGASTCSYPLDTVRRRM--MMTSGQAVKYDGAFDCLRKIVAAEGVGSLFKGCGANILRGVAGAGVISMYDQLQMILFGKKFK-----

General information: TITO was launched using: RESULT: Template: 4C9H.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -42018 for 1672 contacts (-25.1/contact) + 2D Compatibility (PS) -24196 + (NN) 382 + (LL) 4224 1D Compatibility (HY) -14000 + (ID) 3300 Total energy: -78908.0 ( -47.19 by residue) QMean score : 0.147

(partial model without unconserved sides chains): PDB file : Tito_4C9H.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4C9H-query.scw PDB file : Tito_Scwrl_4C9H.pdb: