Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MHREPAKKKAEKRLFDASSFGKDLLAGGVAAAVSKTAVAPIERVKLLLQVQASS-KQISPEARYKGMVDCLVRIPREQGFFSFWRGNLANVIRYFPTQALNFAFKDKYKQLFMSGVNKEKQFWRWFLANLASGGAAGATSLCVVYPLDFARTRLGVDIGKGPEERQFKGLGDCIMKIAKSDGIAGLYQGFGVSVQGIIVYRASYFGAYDTVKGL-LPKPKKTPFLVSFFIAQVVTTCSGILSYPFDTVRRRMMMQSGEAKRQYKGTLDCFVKIYQHEGISSFFRGAFSNVLRGTGGALVLVLYDKIKEFFHIDIGGR 4C9Q Chain:B ((25-313)) -----------------TNFAINFLMGGVSAAIAKTAASPIERVKILIQNQDEMIKQGTLDKKYSGIVDCFKRTAKQEGLISFWRGNTANVIRYFPTQALNFAFKDKIKLMF--GFKKEEGYGKWFAGNLASGGAAGALSLLFVYSLDFARTRLAADA-----ARQFNGLTDVYKKTLKSDGIAGLYRGFMPSVVGIVVYRGLYFGMFDSLKPLV-------SFLASFLLGWVVTTGASTCSYPLDTVRRRMMMTSGQAVK-YNGAIDCLKKIVASEGVGSLFKGCGANILRSVAGAGVISMYDQLQMILFGKKF--

General information: TITO was launched using: RESULT: Template: 4C9Q.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -83968 for 2055 contacts (-40.9/contact) + 2D Compatibility (PS) -27825 + (NN) 1267 + (LL) 1800 1D Compatibility (HY) -28000 + (ID) 7800 Total energy: -144526.0 ( -70.33 by residue) QMean score : 0.219

(partial model without unconserved sides chains): PDB file : Tito_4C9Q.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4C9Q-query.scw PDB file : Tito_Scwrl_4C9Q.pdb: